Drug and Medication Analysis & Statistics, January 2015 (p30)

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Adherens Junction Targeting in Oncology Drug Pipeline Update 2015

Adherens Junction Targeting in Oncology Drug Pipeline Update 2015

  • $ 2 249
  • Industry report
  • January 2015
  • by Bioseeker

Cell-cell adherens junctions, the most common type of intercellular adhesions, are important for maintaining tissue architecture and cell polarity and can limit cell movement and proliferation. There are ...

  • Industries : Drug and Medication
Calcium Signaling Pathway in Cancer Drug Pipeline Update 2015

Calcium Signaling Pathway in Cancer Drug Pipeline Update 2015

  • $ 2 249
  • Industry report
  • January 2015
  • by Bioseeker

There are today 183 companies plus partners developing 213 calcium signaling pathway targeting drugs in 865 developmental projects in cancer. In addition, there is 1 suspended drug and the accumulated ...

  • Industries : Drug and Medication
Targeting Cell Adhesion Molecules (CAMs) for the Treatment of Cancer Drug Pipeline Update 2015

Targeting Cell Adhesion Molecules (CAMs) for the Treatment of Cancer Drug Pipeline Update 2015

  • $ 1 499
  • Industry report
  • January 2015
  • by Bioseeker

Cell adhesion molecules are (glyco)proteins expressed on the cell surface and play a critical role in a wide array of biologic processes that include hemostasis, the immune response, inflammation, embryogenesis, ...

  • Industries : Drug and Medication
Cell Cycle Targeting in Cancer Drug Pipeline Update 2015

Cell Cycle Targeting in Cancer Drug Pipeline Update 2015

  • $ 2 249
  • Industry report
  • January 2015
  • by Bioseeker

There are today 147 companies plus partners developing 144 targeting the cell cycle drugs in 586 developmental projects in cancer. In addition, there are 2 suspended drugs and the accumulated number of ...

  • Industries : Drug and Medication
Interfering With Cytokine-Cytokine Receptor Interaction for the Treatment of Cancer Drug Pipeline Update 2015

Interfering With Cytokine-Cytokine Receptor Interaction for the Treatment of Cancer Drug Pipeline Update 2015

  • $ 2 249
  • Industry report
  • January 2015
  • by Bioseeker

Cytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell growth, ...

  • Industries : Drug and Medication
Interfering With the ECM-Receptor Interaction for the Treatment of Cancer Drug Pipeline Update 2015

Interfering With the ECM-Receptor Interaction for the Treatment of Cancer Drug Pipeline Update 2015

  • $ 749
  • Industry report
  • January 2015
  • by Bioseeker

The extracellular matrix (ECM) consists of a complex mixture of structural and functional macromolecules and serves an important role in tissue and organ morphogenesis and in the maintenance of cell and ...

  • Industries : Drug and Medication
Fc Epsilon RI Signaling Pathway in Oncology Drug Pipeline Update 2015

Fc Epsilon RI Signaling Pathway in Oncology Drug Pipeline Update 2015

  • $ 2 249
  • Industry report
  • January 2015
  • by Bioseeker

Fc epsilon RI-mediated signaling pathways in mast cells are initiated by the interaction of antigen (Ag) with IgE bound to the extracellular domain of the alpha chain of Fc epsilon RI. The activation pathways ...

  • Industries : Drug and Medication
Targeting Focal Adhesion for the Treatment of Cancer Drug Pipeline Update 2015

Targeting Focal Adhesion for the Treatment of Cancer Drug Pipeline Update 2015

  • $ 2 249
  • Industry report
  • January 2015
  • by Bioseeker

Cell-matrix adhesions play essential roles in important biological processes including cell motility, cell proliferation, cell differentiation, regulation of gene expression and cell survival. At the ...

  • Industries : Drug and Medication
Gap Junctions in Oncology Drug Pipeline Update 2015

Gap Junctions in Oncology Drug Pipeline Update 2015

  • $ 2 249
  • Industry report
  • January 2015
  • by Bioseeker

Gap junctions contain intercellular channels that allow direct communication between the cytosolic compartments of adjacent cells. Each gap junction channel is formed by docking of two 'hemichannels', ...

  • Industries : Drug and Medication
GnRH Signaling Pathway in Oncology Drug Pipeline Update 2015

GnRH Signaling Pathway in Oncology Drug Pipeline Update 2015

  • $ 2 249
  • Industry report
  • January 2015
  • by Bioseeker

Gonadotropin-releasing hormone (GnRH) secretion from the hypothalamus acts upon its receptor in the anterior pituitary to regulate the production and release of the gonadotropins, LH and FSH. There are ...

  • Industries : Drug and Medication
Jak-STAT Signaling Pathway in Oncology Drug Pipeline Update 2015

Jak-STAT Signaling Pathway in Oncology Drug Pipeline Update 2015

  • $ 2 249
  • Industry report
  • January 2015
  • by Bioseeker

The Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway is one of a handful of pleiotropic cascades used to transduce a multitude of signals for development and homeostasis ...

  • Industries : Drug and Medication
The MAPK Signaling Pathway in Oncology Drug Pipeline Update 2015

The MAPK Signaling Pathway in Oncology Drug Pipeline Update 2015

  • $ 2 249
  • Industry report
  • January 2015
  • by Bioseeker

The mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. There are today ...

  • Industries : Drug and Medication
Immunotherapy in Oncology Drug Pipeline Update 2015

Immunotherapy in Oncology Drug Pipeline Update 2015

  • $ 3 675
  • Industry report
  • January 2015
  • by Bioseeker

Cancer immunotherapy offers an attractive therapeutic addition, delivering treatment of high specificity, low toxicity and prolonged activity. In this Drug Pipeline Update BioSeeker brings together the ...

  • Industries : Drug and Medication
Angiogenesis in Oncology Drug Pipeline Update 2015

Angiogenesis in Oncology Drug Pipeline Update 2015

  • $ 2 249
  • Industry report
  • January 2015
  • by Bioseeker

There are today 317 companies plus partners developing 350 angiogenesis drugs in 1693 developmental projects in cancer. In addition, there are 8 suspended drugs and the accumulated number of ceased drugs ...

  • Industries : Drug and Medication
Antibodies in Oncology Drug Pipeline Update 2015

Antibodies in Oncology Drug Pipeline Update 2015

  • $ 2 249
  • Industry report
  • January 2015
  • by Bioseeker

The commercial and therapeutic success of antibodies like Rituxan, Avastin, and Erbitux will force the industry to look into the next generation of therapeutic antibodies, preparing themselves for the ...

  • Industries : Drug and Medication
Apoptosis in Oncology Drug Pipeline Update 2015

Apoptosis in Oncology Drug Pipeline Update 2015

  • $ 2 249
  • Industry report
  • January 2015
  • by Bioseeker

Cancer cells frequently and possibly invariably possess apoptotic defects. In this context, apoptotic pathways provide exciting molecular targets for new therapeutic agents to specifically promote apoptosis ...

  • Industries : Drug and Medication
Breast Cancer Drug Pipeline Update 2015

Breast Cancer Drug Pipeline Update 2015

  • $ 2 249
  • Industry report
  • January 2015
  • by Bioseeker

Breast cancer is the leading cause of cancer-related mortality among women worldwide. High unmet needs still persist for this tumor type. Despite recent drug approvals in the adjuvant and metastatic setting, ...

  • Industries : Drug and Medication
Cancer Vaccines Drug Pipeline Update 2015

Cancer Vaccines Drug Pipeline Update 2015

  • $ 2 249
  • Industry report
  • January 2015
  • by Bioseeker

Cancer vaccines offer an attractive therapeutic addition, delivering treatment of high specificity, low toxicity and prolonged activity. However, despite years of R&D, a reproducible survival benefit has ...

  • Industries : Drug and Medication
Cellular Therapy in Oncology Drug Pipeline Update 2015

Cellular Therapy in Oncology Drug Pipeline Update 2015

  • $ 1 499
  • Industry report
  • January 2015
  • by Bioseeker

There are today 101 companies plus partners developing 120 cellular therapy drugs in 252 developmental projects in cancer. In addition, there are 6 suspended drugs and the accumulated number of ceased ...

  • Industries : Drug and Medication
Colorectal Cancer Drug Pipeline Update 2015

Colorectal Cancer Drug Pipeline Update 2015

  • $ 2 249
  • Industry report
  • January 2015
  • by Bioseeker

Until a decade ago, 5FU/leucovorin formed the mainstay of colorectal cancer treatment but Camptosar and Eloxatin quickly established themselves as components of gold-standard therapy. The advent of Avastin ...

  • Industries : Drug and Medication
Cytokine Therapy in Oncology Drug Pipeline Update 2015

Cytokine Therapy in Oncology Drug Pipeline Update 2015

  • $ 1 499
  • Industry report
  • January 2015
  • by Bioseeker

There are today 81 companies plus partners developing 100 cytokine drugs in 214 developmental projects in cancer. In addition, there is 1 suspended drug and the accumulated number of ceased drugs ove ...

  • Industries : Drug and Medication
Gene Therapy in Oncology Drug Pipeline Update 2015

Gene Therapy in Oncology Drug Pipeline Update 2015

  • $ 2 249
  • Industry report
  • January 2015
  • by Bioseeker

There are today 122 companies plus partners developing 100 gene therapy drugs in 280 developmental projects in cancer. In addition, there are 4 suspended drugs and the accumulated number of ceased drugs ...

  • Industries : Drug and Medication
Head and Neck Cancer Drug Pipeline Update 2015

Head and Neck Cancer Drug Pipeline Update 2015

  • $ 2 249
  • Industry report
  • January 2015
  • by Bioseeker

There are today 149 companies plus partners developing 168 drugs targeting head and neck cancer in development. In addition, there are 2 suspended drugs and the accumulated number of ceased drugs ove ...

  • Industries : Drug and Medication
Hematological Cancers Drug Pipeline Update 2015

Hematological Cancers Drug Pipeline Update 2015

  • $ 2 999
  • Industry report
  • January 2015
  • by Bioseeker

Unmet needs across the hematological malignancies remain high, with most traditional therapies conferring low levels of specificity and high toxicity. There are today 485 companies plus partners developing ...

  • Industries : Drug and Medication
Lymphoma Drug Pipeline Update 2015

Lymphoma Drug Pipeline Update 2015

  • $ 2 249
  • Industry report
  • January 2015
  • by Bioseeker

Lymphoma is a broad term encompassing a variety of cancers of the lymphatic system. There are today 263 companies plus partners developing 378 lymphoma drugs in 694 developmental projects in cancer. In ...

  • Industries : Pathology, Drug and Medication
Neuroendocrine Tumors Drug Pipeline Update 2015

Neuroendocrine Tumors Drug Pipeline Update 2015

  • $ 1 499
  • Industry report
  • January 2015
  • by Bioseeker

There are today 85 companies plus partners developing 90 neuroendocrine tumor drugs in 138 developmental projects in cancer. In addition, there is 1 suspended drug and the accumulated number of ceased ...

  • Industries : Drug and Medication
Peptides in Oncology Drug Pipeline Update 2015

Peptides in Oncology Drug Pipeline Update 2015

  • $ 2 249
  • Industry report
  • January 2015
  • by Bioseeker

There are today 252 companies plus partners developing 237 peptide drugs in 622 developmental projects in cancer. In addition, there are 4 suspended drugs and the accumulated number of ceased drugs ove ...

  • Industries : Drug and Medication
Prostate Cancer Drug Pipeline Update 2015

Prostate Cancer Drug Pipeline Update 2015

  • $ 2 249
  • Industry report
  • January 2015
  • by Bioseeker

Cancer of the prostate is the second most frequently diagnosed cancer in men in the US. The prostate cancer market is reaching maturity, and major players` sales have been eroded by the launch of various ...

  • Industries : Drug and Medication
Radiation Therapy in Oncology Drug Pipeline Update 2015

Radiation Therapy in Oncology Drug Pipeline Update 2015

  • $ 2 249
  • Industry report
  • January 2015
  • by Bioseeker

This drug pipeline update is structured around radiolabeled drugs, radiosensitizers and radioprotective compounds. There are today 322 companies plus partners developing 316 radiation therapy drugs in ...

  • Industries : Drug and Medication
Proteins in Oncology Drug Pipeline Update 2015

Proteins in Oncology Drug Pipeline Update 2015

  • $ 2 249
  • Industry report
  • January 2015
  • by Bioseeker

This drug pipeline update covers proteins, excluding antibodies, as drugs for the treatment of cancer. There are today 332 companies plus partners developing 331 protein drugs in 687 developmental projects ...

  • Industries : Drug and Medication
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