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What are the most profitable therapies? Market trends and strategies explained

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Global Therapy Industry 


The global therapy industry (one large revenue center of the pharma industry) involves treatments intended to protect from, cure or manage specific illnesses. The treatment of each therapeutic area and its specific conditions varies widely.


Therapy is usually decided on once the patient has been diagnosed with a specific medical condition or disease, though therapies may also be preventive measures. Therapies applied following diagnosis are either abortive or supportive. The former is a curative measure that seeks to inhibit development of the condition, while the latter relieves the patient’s suffering due to the symptoms of the disease without treating the condition itself.


Preventive therapies are used to safeguard people against disease; for example, vaccinations are used to prevent infections such as polio, smallpox and measles.


Market Trends


The combined market for medicines and therapies used in the treatment of disease is witnessing a slower rate of spending: in the five years up to 2010, spending on medicines grew by more than 6% yearly. However, in the five years up to 2015, the rate of growth is slowing to between 3% and 6%. Global spending on medicine and therapy in 2015 is forecast to reach $1.1 trillion, reports the IMS Institute for Healthcare and Informatics.


The market is to see increased spending on generic drugs, hitting almost 40% growth in 2015 or nearly doubling in a decade. Spending on brand-name medicines should drop by $120 billion in the five-year period ending in 2015.


Increased prevalence of type 2 diabetes, particularly in emerging markets such as China, Brazil and India, will see global spending on the disease rise 4%-7% through 2015, with oral antidiabetics increasingly favored. Spending on therapeutic medicine to treat asthma and chronic obstructive lung disease will drop from 9% in the five-year period ending in 2010 to 2%-5% from 2010 to 2015.



Therapy Spending Forecasts to 2015 *In US$ Billion 



Key Market Segments


According to a report by the IMS Institute for Healthcare Informatics, oncology will continue to hold the top spot in the therapies industry, with forecast revenue between $75 billion and $80 billion in 2015, representing a jump of more than $20 billion in a five-year period. Lipid regulators will fall from second to fourth place, reaching between $29 billion and $34 billion in the same period. Meanwhile, anti-diabetics will rise to second place at between $43 billion and $48 billion.


Respiratory agents are expected to remain the third-biggest seller, with a $5 billion to $10 billion increase on 2010 sales. Drugs to treat hypertension are forecast to rise to fifth place with an up to $6.5 billion increase in revenue. Overall, auto-immune drugs should see a substantial jump to reach between $27 billion and $32 billion by 2015.


HIV antivirals are expected to jump from tenth to seventh place with sales of between $20 billion and $24 billion by 2015. A substantial drop in market share is expected for antidepressants, from more than $20 billion in 2010 to between $13 billion and $16 billion in 2015.  Treatments for multiple sclerosis should rise several places in the same period, marking revenue from under $10 billion to between $12 billion and $15 billion. Antipsychotics are forecast to see a $5 billion drop to $20 billion in 2015.


Therapy segments expected to drop out of the top-20 list include vitamins and minerals, antirheumatics, cephalosporins, combs (antibiotics) and vaccines. Categories expected to appear in the top 20 include treatments for glaucoma, Alzheimer’s, osteoporosis and attention deficit hyperactivity disorder.


Categories expected to show less substantial fluctuation include narcotic analgesics, antiepileptics and erythropoietics.



Top 20 Global Therapeutic Categories (2015) 



Regional Market Share


  • Spending on therapeutic medicine in the US is expected to show a slower growth rate, bringing its stake in global spending down by 10% to reach just over 30% in 2015. In 2010, the therapeutics class with the largest market share in the US was oncologics (radiation therapy) at almost $60 billion, followed by lipid regulators and respiratory agents at almost $36.5 billion and close to $36 billion respectively, according to IMS Health. Antidiabetics represented the fourth-largest market share, with revenue just under $35 billion.


  • Antiulcerants, angiotestin-II receptor antagonists (used to lower blood pressure), and antipsychotics all fell within the $25 billion-$28 billion range. Autoimmune agents accounted for just under $21 billion of the market, and antidepressants settled at just over $20 billion.


  • Spending in the five leading EU countries will equally slow 7% to 13% in the same period.


  • However, slowing growth is not across the board, with developing markets seeing a move in the opposite direction. China will lead these markets with spending expected to more than double in a decade to reach 28% by 2015. Spending in emerging markets will see a $150 billion rise by 2015.



Market Outlook


With cases of cancer and diabetes rising at unprecedented rates, oncology and antidiabetes therapies continue to lead the therapeutic market. The market for radiation therapy devices is expected to reach $3.5 billion by 2017, according to Global Data, representing a 10% compound annual growth rate. A sub segment of the market, electron beam radiation therapy systems, is forecast to grow at 9% annually.


With more than 365 million people diagnosed with diabetes in the world at present and an estimation of more than 4.5 million deaths from the disease in 2011, spending on research and demand for antidiabetic therapies is set to continue its steep climb. Without a radical change in lifestyle habits, it is estimated that one in three people in the US will have diabetes by 2050, representing an ever-increasing market.



Leading Associations




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