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Global Markets for Medical Imaging Reagents and Analysis Equipment

Medical Imaging

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Global Markets for Medical Imaging Reagents and Analysis Equipment

Publication date: January 2013
Report size: 195 pages

Keywords : X-Ray, Computed Tomography, Medical Imaging, tomography, Ultrasound, radiopharmaceutical, Positron Emission Tomography, magnetic resonance image, radiography, MRI contrast agent, computed tomography scanner

INTRODUCTION STUDY OBJECTIVES BCC’s goal in conducting this study is to provide an overview of the current and future characteristics of the global market for medical imaging technologies, which includes both the imaging systems and the contrast agents. The key objective is to present a comprehensive analysis and future direction of imaging techniques as an important tool for the usage in medical diagnostic procedure...

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INTRODUCTION

STUDY OBJECTIVES

BCC’s goal in conducting this study is to provide an overview of the current and future characteristics of the global market for medical imaging technologies, which includes both the imaging systems and the contrast agents. The key objective is to present a comprehensive analysis and future direction of imaging techniques as an important tool for the usage in medical diagnostic procedures.

This report explores present and future strategies within the medical imaging technology market, which includes X-ray imaging, ultrasound, computed tomography, magnetic resonance imaging and positron emission tomography. The improvisation of the market as well as the setbacks and needs of the market are discussed in this report. The classifications, comparisons, advantages and disadvantages and usage of these types of diagnostic methods are also listed in this report.

A detailed analysis of medical imaging industry structure has been conducted. Revenues are broken down by the region and sales figures are estimated for the five-year period from 2011 through 2017.

Applications for medical imaging technologies are also discussed separately in the report, with an emphasis of the usage of the inhibitors in therapeutic categories and various disease sectors. The report also covers significant patents and their allotments in each category.

REASONS FOR DOING THIS STUDY

Extensive research and new developments in the field of medical imaging technology has improved their usage in being able to be used as a prime diagnostic tool for various diseases and other medical conditions. Modern industries continue to explore the advantages of medical imaging technologies, leading to the steady market growth due to higher production of the imaging systems. This study is an update to the one published in January 2010.

R&D spending, along with increasing competition, new technologies, new advancements and new product launches have influenced the market to grow in the foreseeable future. This study looks at many of the systems affected by these factors.

Acquisition strategies and collaborations by companies are also covered in this report. This study also discusses the strength and weaknesses of each type/ technology in light of new technologies, growing competition and changing customer needs.

CONTRIBUTIONS OF THE STUDY AND INTENDED AUDIENCE

This study contributes to the areas of market growth in medical imaging (imaging systems and contrast agents) product manufacturers and users. Pharmaceutical, biotechnical companies, research institutes, hospitals and physicians will find this study to be of interest.

SCOPE OF THE STUDY

The scope of this study encompasses imaging technology in the field of medicine. BCC analyzes each imaging market and its applications, regulatory environment, technology, market projections and market shares. Technological issues include the latest trends and developments. The emerging market for enzyme inhibitors includes countries such as India, China, Japan, Korea, Taiwan, Canada, Africa, Australia and New Zealand, among others.

METHODOLOGY

Both primary and secondary research methodologies were used in preparing this study. BCC conducted a comprehensive literature search, which included technical newsletters and journals, and many other sources. Data were collected through interviews and correspondence with manufacturers of imaging systems and contrast agents technical experts. Projections were based on estimates such as the current number of end users, potential end users, mergers and acquisitions, and market trends.

INFORMATION SOURCES

Many companies were surveyed to obtain data for this study. Included were manufacturers and end users of medical imaging technologies in various types of disease sectors industries. Data were gathered from various industry sources. BCC spoke with officials within the industry, consulted newsletters, company literature, product literature and a host of technical articles, journals, indexes and abstracts. Exhaustive investigations of databases by key terminology were completed. In addition, data were compiled from current financial, trade and government sources.

ABOUT THE AUTHOR

A team of professionals in the biotechnology industry carried out this study. The project manager is Shalini S. Dewan, who holds a master’s degree in pharmaceutical chemistry and has over 14 years of industry experience. Among the research topics she has covered are studies on compounds of potential pharmaceutical interest from ibuprofen and 2-naphthyl acetic acid. Shalini was awarded a Gold Medal by the Prime Minister of India for her work and has worked with top companies in India and in the U.S. Some of her other reports with BCC are: Reagents for Chromatography; Spectroscopy: An Enduring Market; Advanced Drug Delivery Systems: Technologies and Global Markets; Orthopedic Drugs, Implants and Devices; Medical Imaging Reagents and Analysis Equipment; Pharmaceutical Regulatory Industry; The Dynamic Media, Sera and Reagent Market in Biotechnology; Contract Pharmaceutical Manufacturing, Research and Packaging: Global Markets; Chiral Technology: Global Markets; Autacoids and Related Drugs: Technologies and Global Markets; Contraceptives: Technologies and Global Markets; Liver Disease Treatments: The Global Market; Hormone Replacement Therapies and Other Hormone Therapies: Global Markets; Cardiovascular Medicine: Diagnostics, Drugs and Devices; and Cancer Therapies: Technologies and Global Markets.

The lead consultant for this project was Dr. Kapil A. Setia, who holds a doctoral degree in the life sciences. She has a number of research publications to her credit.

Global Medical Imaging Industry

TABLE OF CONTENTS

CHAPTER 1 INTRODUCTION 1
STUDY OBJECTIVES 1
REASONS FOR DOING THIS STUDY 1
CONTRIBUTIONS OF THE STUDY AND INTENDED AUDIENCE 1
SCOPE OF THE STUDY 2
METHODOLOGY 2
INFORMATION SOURCES 2
ABOUT THE AUTHOR 2
RELATED BCC RESEARCH REPORTS 3
BCC ONLINE SERVICES 3
DISCLAIMER 3
CHAPTER 2 SUMMARY 5
SUMMARY TABLE GLOBAL REVENUE OF MEDICAL IMAGING MARKET, THROUGH 2017 ($
MILLIONS) 6
SUMMARY FIGURE GLOBAL REVENUE OF MEDICAL IMAGING MARKET, 2010-2017 ($
MILLIONS) 6
CHAPTER 3 OVERVIEW 8
DEFINITIONS 8
TYPES OF MEDICAL IMAGING 8
X-RAY IMAGING 8
History and Development of X-ray Imaging 9
TABLE 1 HISTORY AND DEVELOPMENT OF X-RAY IMAGING 9
Properties of X-ray 10
Applications of X-ray in Medicine 10
Advantages and Disadvantages of X-ray 11
TABLE 2 ADVANTAGES AND DISADVANTAGES OF X-RAY 11
ULTRASOUND 11
History and Development of Ultrasound 12
TABLE 3 HISTORY AND DEVELOPMENT OF ULTRASOUND 12
Diagnostic Applications of Ultrasound 13
Therapeutic Applications of Ultrasound 13
Advantages and Disadvantages of Ultrasound 14
TABLE 4 ADVANTAGES AND DISADVANTAGES OF ULTRASOUND 14
MAGNETIC RESONANCE IMAGING 14
History and Development of Magnetic Resonance Imaging 15
TABLE 5 HISTORY AND DEVELOPMENT OF MRI 15
Applications of Magnetic Resonance Imaging 15
Advantages and Disadvantages of MRI 16
TABLE 6 ADVANTAGES AND DISADVANTAGES OF MRI 16
COMPUTED TOMOGRAPHY 16
Applications of Computed Tomography 17
Advantages and Disadvantages of Computed Tomography 18
TABLE 7 ADVANTAGES AND DISADVANTAGES OF COMPUTED TOMOGRAPHY 18
POSITRON EMISSION TOMOGRAPHY 18
History and Development of Positron Emission Technology 19
TABLE 8 HISTORY AND DEVELOPMENT OF POSITRON EMISSION TECHNOLOGY 19
Advantages and Disadvantages of PET 20
TABLE 9 ADVANTAGES AND DISADVANTAGES OF PET 20
COMPARISON OF VARIOUS IMAGING MODALITIES 21
TABLE 10 DIFFERENCES BETWEEN CT AND MRI 21
TABLE 11 DIFFERENCES BETWEEN CT AND ULTRASOUND 22
TABLE 12 DIFFERENCES BETWEEN CT AND PET 22
TABLE 13 DIFFERENCES BETWEEN MRI AND X-RAY 23
CONTRAST AGENTS 23
PROPERTIES OF AN IDEAL CONTRAST AGENT 23
UNDESIRABLE EFFECTS OF CONTRAST AGENTS 23
Allergic Reactions 23
Acute Renal Failure 24
Aspiration 24
Pulmonary Edema 24
Seizure 24
CLASSIFICATION OF CONTRAST AGENTS BASED ON THEIR PROPERTIES 24
Positive Contrast Agents 24
Negative Contrast Agents 24
CLASSIFICATION OF CONTRAST AGENTS BASED ON THE TYPE OF IMAGING
TECHNIQUE 25
Contrast Agents for X-ray 25
TABLE 14 ADVANTAGES AND DISADVANTAGES OF BARIUM AS CONTRAST MEDIUM 25
Contrast Agents for Magnetic Resonance Imaging 26
Nonspecific Extracellular Agents 26
TABLE 15 NONSPECIFIC EXTRACELLULAR CONTRAST AGENTS 26
Tissue-Specific Contrast Agents 27
TABLE 16 LIVER-SPECIFIC CONTRAST AGENTS 27
Contrast Agents for Ultrasound 27
PET Radiopharmaceuticals 28
TABLE 17 COMMONLY USED RADIOPHARMACEUTICALS 28
IMAGING EQUIPMENT 29
X-RAY IMAGING SYSTEM 29
FLUOROSCOPY EQUIPMENT 30
COMPUTED TOMOGRAPHY SCANNER 30
Types of Computed Tomography Scanning 30
Advances in CT Scanners /Types of CT Scanners 30
ULTRASOUND MACHINES 31
MAGNETIC RESONANCE IMAGING SYSTEM 32
POSITRON EMISSION TOMOGRAPHY EQUIPMENT 33
CHAPTER 4 REGULATORY ISSUES 35
APPROVALS IN THE FIELD OF MEDICAL IMAGING 35
NEW APPROVALS 35
TABLE 18 NEW APPROVAL OF IMAGING SYSTEMS, 2008-AUGUST 2012 35
510(K) APPROVALS 36
TABLE 19 510(K) APPROVALS FOR ULTRASOUND SYSTEMS, 2008–AUGUST 2012 36
TABLE 20 510(K) APPROVALS FOR MRI SYSTEMS, 2008-AUGUST 2012 42
TABLE 21 510(K) APPROVALS FOR X-RAY/CT SYSTEMS, 2008–AUGUST 2012 43
TABLE 22 510(K) APPROVALS FOR PET SYSTEMS, 2008–AUGUST 2012 46
RECALLS 46
TABLE 23 RECALLS FOR MAGNETIC RESONANCE IMAGING SYSTEMS 46
TABLE 24 RECALLS FOR X-RAY AND COMPUTED TOMOGRAPHY SYSTEMS,
2008—SEPTEMBER 2012 48
TABLE 25 RECALLS FOR ULTRASOUND SYSTEMS, 2008-SEPTEMBER 2012 52
TABLE 26 RECALLS FOR PET SYSTEMS, 2008—SEPTEMBER 2012 56
APPROVALS FOR CONTRAST AGENTS 57
TABLE 27 APPROVAL OF CONTRAST AGENTS 58
SAFETY ALERTS 59
TABLE 28 SAFETY ALERTS FOR CONTRAST AGENTS, 2008—SEPTEMBER 2012 59
CHAPTER 5 NEW DEVELOPMENTS/ TECHNOLOGICAL INNOVATIONS 62
TABLE 29 NEW DEVELOPMENTS IN CONTRAST AGENTS 62
TABLE 30 NEW DEVELOPMENTS IN COMPUTED TOMOGRAPHY 62
TABLE 31 NEW DEVELOPMENTS IN MAGNETIC RESONANCE IMAGING 63
TABLE 32 NEW DEVELOPMENTS IN POSITRON EMISSION TOMOGRAPHY 63
TABLE 33 NEW DEVELOPMENTS IN ULTRASOUND 64
TABLE 34 NEW DEVELOPMENTS IN RADIOGRAPHY (X-RAY, MAMMOGRAPHY AND
FLUOROSCOPY) 66
CHAPTER 6 GLOBAL MARKET ANALYSIS FOR IMAGING TECHNOLOGIES 68
MARKET FOR CONTRAST AGENTS BY IMAGING TECHNOLOGY 69
MARKET OVERVIEW 69
MARKET REVENUE 71
TABLE 35 GLOBAL MARKET FOR CONTRAST AGENTS, BY IMAGING TECHNOLOGY,
THROUGH 2017 ($ MILLIONS) 71
FIGURE 1 GLOBAL MARKET FOR CONTRAST AGENTS, BY IMAGING TECHNOLOGY,
2010–2017 ($ MILLIONS) 71
MARKET SHARE 72
TABLE 36 GLOBAL MARKET SHARES FOR CONTRAST AGENTS, BY IMAGING TECHNOLOGY
2011 (%) 72
FIGURE 2 GLOBAL MARKET SHARES FOR CONTRAST AGENTS, BY IMAGING TECHNOLOGY,
2011 (%) 72
MARKET FOR IMAGING SYSTEMS BY IMAGING TECHNOLOGY 73
MARKET OVERVIEW 73
MARKET REVENUE 76
TABLE 37 GLOBAL MARKET FOR IMAGING SYSTEMS, BY IMAGING TECHNOLOGY, THROUGH
2017 ($ MILLIONS) 77
FIGURE 3 GLOBAL MARKET FOR IMAGING SYSTEMS, BY IMAGING TECHNOLOGY, 2010–2017
($ MILLIONS) 77
MARKET SHARE 77
TABLE 38 MARKET SHARE FOR IMAGING SYSTEMS, BY IMAGING TECHNOLOGY, 2011 (%) 78
FIGURE 4 MARKET SHARE FOR IMAGING SYSTEMS, BY IMAGING TECHNOLOGY, 2011 (%) 78
GLOBAL MARKET FOR CONTRAST AGENTS BY REGION 78
MARKET OVERVIEW 79
MARKET REVENUE 81
TABLE 39 GLOBAL MARKET FOR CONTRAST AGENTS, BY REGION, THROUGH 2017 ($
MILLIONS) 81
FIGURE 5 GLOBAL MARKET FOR CONTRAST AGENTS, BY REGION, 2010–2017 ($ MILLIONS) 81
MARKET SHARE 82
TABLE 40 GLOBAL MARKET SHARE FOR CONTRAST AGENTS, BY REGION, 2011 (%) 82
FIGURE 6 GLOBAL MARKET SHARE FOR CONTRAST AGENTS, BY REGION, 2011 (%) 82
MARKET FOR IMAGING SYSTEMS BY REGION 82
MARKET OVERVIEW 83
MARKET REVENUE 85
TABLE 41 GLOBAL MARKET FOR IMAGING SYSTEMS, BY REGION, THROUGH 2017 ($
MILLIONS) 86
FIGURE 7 GLOBAL MARKET FOR IMAGING SYSTEMS, BY REGION, 2010–2017 ($ MILLIONS) 86
MARKET SHARE 86
TABLE 42 GLOBAL MARKET SHARES FOR IMAGING SYSTEMS, BY REGION, 2011 (%) 87
FIGURE 8 GLOBAL MARKET SHARE FOR IMAGING SYSTEMS BY REGION, 2011 (%) 87
MARKET BY APPLICATIONS 87
TABLE 43 GLOBAL REVENUE FOR IMAGING CONTRAST AGENTS AND SYSTEMS USED FOR
VARIOUS DISEASES, THROUGH 2017 ($ MILLIONS) 92
FIGURE 9 GLOBAL REVENUE FOR IMAGING CONTRAST AGENTS AND SYSTEMS USED FOR
VARIOUS DISEASES, 2010–2017 ($ MILLIONS) 92
MARKET SHARE 93
TABLE 44 GLOBAL REVENUE MARKET SHARE FOR IMAGING CONTRAST AGENTS AND
SYSTEMS USED FOR VARIOUS DISEASES, 2011 (%) 94
FIGURE 10 GLOBAL REVENUE MARKET SHARE FOR IMAGING CONTRAST AGENTS AND
SYSTEMS USED FOR VARIOUS DISEASES, 2011 (%) 94
CHAPTER 7 MARKET ANALYSIS FOR X-RAYS AND COMPUTED TOMOGRAPHY 96
MARKET FOR CONTRAST AGENTS BY REGION 96
MARKET OVERVIEW 96
MARKET REVENUE 97
TABLE 45 GLOBAL MARKET FOR X-RAY AND CT AGENTS BY REGION, THROUGH 2017 ($
MILLIONS) 98
FIGURE 11 GLOBAL MARKET FOR X-RAY AND CT AGENTS BY REGION, 2010-2017 ($
MILLIONS) 98
MARKET SHARE 98
TABLE 46 MARKET SHARE OF X-RAY AND CT REAGENTS BY REGION, 2011 (%) 99
FIGURE 12 MARKET SHARE OF X-RAY AND CT REAGENTS BY REGION, 2011 (%) 99
MARKET BY TYPE OF IMAGING SYSTEMS 99
MARKET OVERVIEW 99
MARKET REVENUE 100
TABLE 47 GLOBAL MARKET FOR IMAGING SYSTEMS, BY TYPE, THROUGH 2017 ($ MILLIONS) 100
FIGURE 13 GLOBAL MARKET FOR IMAGING SYSTEMS, BY TYPE, THROUGH 2017 ($
MILLIONS) 100
MARKET SHARE 101
TABLE 48 MARKET SHARE OF IMAGING SYSTEMS BY TYPE, 2011 (%) 101
FIGURE 14 MARKET SHARE OF IMAGING SYSTEMS BY TYPE, 2011 (%) 101
MARKET FOR X-RAY IMAGING SYSTEMS BY REGION 102
MARKET OVERVIEW 102
MARKET REVENUE 103
TABLE 49 GLOBAL MARKET FOR X-RAY SYSTEMS BY REGION, THROUGH 2017 ($ MILLIONS) 104
FIGURE 15 GLOBAL MARKET FOR X-RAY SYSTEMS BY REGION, 2010-2017 ($ MILLIONS) 104
MARKET SHARE 104
TABLE 50 MARKET SHARE OF X-RAY SYSTEMS BY REGION, 2011 (%) 105
FIGURE 16 MARKET SHARE OF X-RAY SYSTEMS BY REGION, 2011 (%) 105
MARKET FOR CT IMAGING SYSTEMS BY REGION 105
MARKET OVERVIEW 106
MARKET REVENUE 107
TABLE 51 GLOBAL MARKET FOR COMPUTED TOMOGRAPHY SYSTEMS BY REGION,
THROUGH 2017 ($ MILLIONS) 107
FIGURE 17 GLOBAL MARKET FOR COMPUTED TOMOGRAPHY SYSTEMS BY REGION,
2010-2017 ($ MILLIONS) 107
MARKET SHARE 108
TABLE 52 MARKET SHARE OF COMPUTED TOMOGRAPHY SYSTEMS BY REGION, 2011 (%) 108
FIGURE 18 MARKET SHARE OF COMPUTED TOMOGRAPHY SYSTEMS BY REGION, 2011 (%) 109
MARKET BY APPLICATIONS 109
TABLE 53 GLOBAL REVENUE FOR X-RAY AND CT REAGENTS AND SYSTEMS USED FOR
VARIOUS DISEASES, THROUGH 2017 ($ MILLIONS) 109
FIGURE 19 GLOBAL REVENUE FOR X-RAY AND CT REAGENTS AND SYSTEMS USED FOR
VARIOUS DISEASES, 2010-2017 ($ MILLIONS) 109
X-RAY 110
TABLE 54 GLOBAL REVENUE FOR X-RAY AND CT REAGENTS AND SYSTEMS USED FOR
VARIOUS DISEASES, THROUGH 2017 ($ MILLIONS) 112
FIGURE 20 GLOBAL REVENUE FOR X-RAY REAGENTS AND SYSTEMS USED FOR VARIOUS
DISEASES, 2010-2017 ($ MILLIONS) 112
Market Share 113
TABLE 55 X-RAY IMAGING MARKET SHARES, BY APPLICATION, 2011 (%) 113
FIGURE 21 X-RAY IMAGING MARKET SHARES, BY APPLICATION, 2011 (%) 113
COMPUTED TOMOGRAPHY 113
TABLE 56 GLOBAL REVENUE FOR CT REAGENTS AND SYSTEMS USED FOR VARIOUS
DISEASES, THROUGH 2017 ($ MILLIONS) 115
FIGURE 22 GLOBAL REVENUE FOR CT REAGENTS AND SYSTEMS USED FOR VARIOUS
DISEASES, 2010-2017 ($ MILLIONS) 115
Market Share 116
TABLE 57 COMPUTED TOMOGRAPHY IMAGING MARKET SHARES, BY APPLICATION, 2011 (%) 116
FIGURE 23 COMPUTED TOMOGRAPHY IMAGING MARKET SHARES, BY APPLICATION, 2011
(%) 116
INDUSTRY STRUCTURE 117
X-RAY AND COMPUTED TOMOGRAPHY CONTRAST AGENTS 117
Market Leaders 117
TABLE 58 LEADING MANUFACTURERS OF X-RAY AND COMPUTED TOMOGRAPHY
CONTRAST AGENTS 117
Market Shares 117
TABLE 59 GLOBAL MARKET SHARES OF X-RAY AND COMPUTED TOMOGRAPHY CONTRAST
AGENTS, 2011 (%) 118
FIGURE 24 GLOBAL MARKET SHARES OF X-RAY AND COMPUTED TOMOGRAPHY CONTRAST
AGENTS, 2011 (%) 118
X-RAY IMAGING SYSTEMS 118
Market Leaders 118
TABLE 60 LEADING MANUFACTURERS OF RADIOGRAPHY (X-RAY, FLUOROSCOPY AND
MAMMOGRAPHY) IMAGING SYSTEMS 119
Market Shares 122
TABLE 61 GLOBAL MARKET SHARES OF X-RAY IMAGING SYSTEMS, 2011 (%) 122
FIGURE 25 GLOBAL MARKET SHARES OF X-RAY IMAGING SYSTEMS, 2011 (%) 122
COMPUTED TOMOGRAPHY SYSTEMS 123
Market Leaders 123
TABLE 62 LEADING MANUFACTURERS OF COMPUTED TOMOGRAPHY SYSTEMS 123
Market Shares 124
TABLE 63 WORLDWIDE MARKET SHARES OF COMPUTED TOMOGRAPHY SYSTEMS, 2011 (%) 124
FIGURE 26 WORLDWIDE MARKET SHARES OF COMPUTED TOMOGRAPHY SYSTEMS, 2011 (%) 124
CHAPTER 8 MARKET ANALYSIS FOR MAGNETIC RESONANCE IMAGING 126
MARKET FOR CONTRAST AGENTS BY REGION 126
MARKET OVERVIEW 126
MARKET REVENUE 127
TABLE 64 GLOBAL MARKET FOR MRI AGENTS, BY REGION, THROUGH 2017 ($ MILLIONS) 127
FIGURE 27 GLOBAL MARKET FOR MRI AGENTS, BY REGION, 2010-2017 ($ MILLIONS) 127
MARKET SHARE 128
TABLE 65 MARKET SHARE OF MRI REAGENTS BY REGION, 2011 (%) 128
FIGURE 28 MARKET SHARE OF MRI REAGENTS BY REGION, 2011 (%) 128
MARKET FOR IMAGING SYSTEMS BY REGION 129
MARKET OVERVIEW 129
MARKET REVENUE 131
TABLE 66 GLOBAL MARKET FOR MRI SYSTEMS, BY REGION, THROUGH 2017 ($ MILLIONS) 131
FIGURE 29 GLOBAL MARKET FOR MRI SYSTEMS, BY REGION, 2010-2017 ($ MILLIONS) 132
MARKET SHARE 132
TABLE 67 MARKET SHARE OF MRI SYSTEMS, BY REGION, 2011 (%) 132
FIGURE 30 MARKET SHARE OF MRI SYSTEMS, BY REGION, 2011 (%) 132
MARKET BY MAGNETIC STRENGTH 133
MARKET REVENUE 133
TABLE 68 GLOBAL MARKET FOR MRI SYSTEMS, BY MAGNETIC STRENGTH, THROUGH 2017
($ MILLIONS) 134
FIGURE 31 GLOBAL MARKET FOR MRI SYSTEMS, BY MAGNETIC STRENGTH, 2010-2017 ($
MILLIONS) 134
MARKET BY APPLICATIONS 134
TABLE 69 GLOBAL REVENUE FOR MRI REAGENTS AND SYSTEMS USED FOR VARIOUS
DISEASES, THROUGH 2017 ($ MILLIONS) 135
FIGURE 32 GLOBAL REVENUE FOR MRI REAGENTS AND SYSTEMS USED FOR VARIOUS
DISEASES, 2010-2017 ($ MILLIONS) 135
MARKET SHARE 136
TABLE 70 MAGNETIC RESONANCE IMAGING MARKET SHARES, BY APPLICATION, 2011 (%) 137
FIGURE 33 MAGNETIC RESONANCE IMAGING MARKET SHARES, BY APPLICATION, 2011 (%) 137
INDUSTRY STRUCTURE 137
MAGNETIC RESONANCE IMAGING CONTRAST AGENTS 137
Market Leaders 137
TABLE 71 LEADING MANUFACTURERS OF MAGNETIC RESONANCE IMAGING CONTRAST
AGENTS 138
Market Share 138
TABLE 72 GLOBAL MARKET SHARES OF MRI CONTRAST AGENTS, 2011 (%) 138
FIGURE 34 GLOBAL MARKET SHARES OF MRI CONTRAST AGENTS, 2011 (%) 138
NUCLEAR MAGNETIC IMAGING SYSTEMS 139
Market Leaders 139
TABLE 73 LEADING MANUFACTURERS OF NUCLEAR MAGNETIC IMAGING SYSTEMS 139
Market Share 140
TABLE 74 GLOBAL MARKET SHARES OF MRI IMAGING SYSTEMS, 2011 (%) 141
FIGURE 35 GLOBAL MARKET SHARES OF MRI IMAGING SYSTEMS, 2011 (%) 141
CHAPTER 9 MARKET FOR ULTRASOUND IMAGING 143
MARKET FOR CONTRAST AGENTS BY REGION 143
MARKET OVERVIEW 143
MARKET REVENUE 144
TABLE 75 GLOBAL MARKET FOR ULTRASOUND REAGENTS, BY REGION, THROUGH 2017 ($
MILLIONS) 145
FIGURE 36 GLOBAL MARKET FOR ULTRASOUND REAGENTS, BY REGION, 2010-2017
(MILLIONS) 145
MARKET SHARE 145
TABLE 76 MARKET SHARE OF ULTRASOUND REAGENTS, BY REGION, 2011 (%) 146
FIGURE 37 MARKET SHARE OF ULTRASOUND REAGENTS, BY REGION, 2011 (%) 146
MARKET FOR IMAGING SYSTEMS BY REGION 146
MARKET OVERVIEW 146
MARKET REVENUE 148
TABLE 77 GLOBAL MARKET FOR ULTRASOUND SYSTEMS BY REGION, THROUGH 2017 ($
MILLIONS) 148
FIGURE 38 GLOBAL MARKET FOR ULTRASOUND SYSTEMS BY REGION, 2010-2017 ($
MILLIONS) 148
MARKET SHARE 149
TABLE 78 MARKET SHARE OF ULTRASOUND SYSTEMS, BY REGION, 2011 (%) 149
FIGURE 39 MARKET SHARE OF ULTRASOUND SYSTEMS, BY REGION, 2011 (%) 149
MARKET BY APPLICATIONS 149
TABLE 79 GLOBAL REVENUE FOR ULTRASOUND REAGENTS AND SYSTEMS USED FOR
VARIOUS DISEASES, THROUGH 2017 ($ MILLIONS) 151
FIGURE 40 GLOBAL REVENUE FOR ULTRASOUND REAGENTS AND SYSTEMS USED FOR
VARIOUS DISEASES, 2010-2017 ($ MILLIONS) 152
MARKET SHARE 152
TABLE 80 ULTRASOUND IMAGING MARKET SHARES, BY APPLICATION, 2011 (%) 152
FIGURE 41 ULTRASOUND IMAGING MARKET SHARES, BY APPLICATION, 2011 (%) 152
INDUSTRY STRUCTURE 153
ULTRASOUND CONTRAST AGENTS 153
Market Leaders 153
TABLE 81 LEADING MANUFACTURERS OF ULTRASOUND CONTRAST AGENTS 153
Market Share 153
TABLE 82 GLOBAL MARKET SHARES OF ULTRASOUND CONTRAST AGENTS, 2011 (%) 154
FIGURE 42 GLOBAL MARKET SHARES OF ULTRASOUND CONTRAST AGENTS, 2011 (%) 154
ULTRASOUND IMAGING SYSTEMS 154
Market Leaders 154
TABLE 83 LEADING MANUFACTURERS OF ULTRASOUND IMAGING SYSTEMS 155
Market Share 157
TABLE 84 GLOBAL MARKET SHARES OF ULTRASOUND SYSTEMS, 2011 (%) 157
FIGURE 43 GLOBAL MARKET SHARES OF ULTRASOUND SYSTEMS, 2011 (%) 158
CHAPTER 10 MARKET FOR POSITRON EMISSION TOMOGRAPHY 160
MARKET FOR DIAGNOSTIC RADIOPHARMACEUTICALS BY REGION 160
MARKET OVERVIEW 160
MARKET REVENUE 162
TABLE 85 GLOBAL MARKET FOR DIAGNOSTIC RADIOPHARMACEUTICALS BY REGION,
THROUGH 2017 ($ MILLIONS) 162
FIGURE 44 GLOBAL MARKET FOR DIAGNOSTIC RADIOPHARMACEUTICALS BY REGION,
2010-2017 ($ MILLIONS) 162
MARKET SHARE 163
TABLE 86 MARKET SHARES OF DIAGNOSTIC RADIOPHARMACEUTICALS BY REGION, 2011
(%) 163
FIGURE 45 MARKET SHARE OF DIAGNOSTIC RADIOPHARMACEUTICALS BY REGION, 2011
(%) 163
MARKET FOR IMAGING SYSTEMS BY REGION 164
MARKET OVERVIEW 164
MARKET REVENUE 165
TABLE 87 GLOBAL MARKET FOR PET SYSTEMS, BY REGION, THROUGH 2017 ($ MILLIONS) 165
FIGURE 46 GLOBAL MARKET FOR PET SYSTEMS, BY REGION, 2010-2017 ($ MILLIONS) 165
MARKET SHARE 166
TABLE 88 MARKET SHARE OF PET SYSTEMS BY REGION, 2011 (%) 166
FIGURE 47 MARKET SHARE OF PET SYSTEMS BY REGION, 2011 (%) 166
MARKET BY APPLICATIONS 166
TABLE 89 GLOBAL REVENUE FOR PET IMAGING USED FOR VARIOUS DISEASES, THROUGH
2017 ($ MILLIONS) 168
FIGURE 48 GLOBAL REVENUE FOR PET IMAGING USED FOR VARIOUS DISEASES, 2010-2017
($ MILLIONS) 168
MARKET SHARE 169
TABLE 90 POSITRON EMISSION TOMOGRAPHY IMAGING MARKET SHARES, BY
APPLICATION, 2011 (%) 169
FIGURE 49 POSITRON EMISSION TOMOGRAPHY IMAGING MARKET SHARES, BY
APPLICATION, 2011 (%) 169
INDUSTRY STRUCTURE 170
RADIOPHARMACEUTICALS 170
Market Leaders 170
TABLE 91 LEADING MANUFACTURERS OF DIAGNOSTIC RADIOPHARMACEUTICALS 171
Market Share 173
TABLE 92 WORLDWIDE MARKET SHARES OF DIAGNOSTIC RADIOPHARMACEUTICALS, 2011
(%) 173
FIGURE 50 WORLDWIDE MARKET SHARES OF DIAGNOSTIC RADIOPHARMACEUTICALS,
2011 (%) 173
POSITRON EMISSION TOMOGRAPHY SYSTEMS 174
Market Leaders 174
TABLE 93 LEADING MANUFACTURERS OF PET IMAGING SYSTEMS 174
Market Share 175
TABLE 94 WORLDWIDE MARKET SHARES OF PET IMAGING SYSTEMS, 2011 (%) 175
FIGURE 51 WORLDWIDE MARKET SHARES OF PET IMAGING SYSTEMS, 2011 (%) 175
CHAPTER 11 PATENT ANALYSIS 177
CONTRAST AGENTS 177
BY YEAR 177
TABLE 95 TOTAL NUMBER OF PATENTS FOR CONTRAST AGENTS, FROM 2008–JULY 2012 177
BY IMAGING MODALITY 177
TABLE 96 NUMBER OF PATENTS FOR CONTRAST AGENTS BY IMAGING MODALITY, FROM
2008–JULY 2012 178
BY COMPANY 178
TABLE 97 NUMBER OF PATENTS BY COMPANY FROM 2008–JULY 2012 178
BY COUNTRY 178
TABLE 98 NUMBER OF PATENTS BY COUNTRY FROM 2008–JULY 2012 179
BY ASSIGNEE 179
TABLE 99 NUMBER OF PATENTS BY ASSIGNEE FROM 2008–JULY 2012 179
IMAGING SYSTEMS 179
BY YEAR 179
TABLE 100 TOTAL NUMBER OF PATENTS FOR IMAGING MODALITIES FROM 2008–JULY 2012 180
FIGURE 52 TOTAL NUMBER OF PATENTS FOR IMAGING MODALITIES FROM 2008–JULY 2012 180
FIGURE 53 TOTAL NUMBER OF PATENTS FOR IMAGING MODALITIES FROM 2008–JULY 2012
(%) 180
BY IMAGING MODALITY 181
TABLE 101 NUMBER OF PATENTS BY IMAGING MODALITY FROM JANUARY 2008–JULY 2012 181
FIGURE 54 NUMBER OF PATENTS BY IMAGING MODALITY FROM JANUARY 2008-JULY 2012 181
BY COMPANY 181
TABLE 102 NUMBER OF PATENTS BY COMPANY FROM 2008–JULY 2012 182
BY COUNTRY 183
TABLE 103 NUMBER OF PATENTS BY COUNTRY FROM 2008–JULY 2012 184
FIGURE 55 NUMBER OF PATENTS BY COUNTRY FROM 2008–JULY 2012 184
BY ASSIGNEE 185
TABLE 104 NUMBER OF PATENTS BY ASSIGNEE FROM 2008–JULY 2012 185
FIGURE 56 NUMBER OF PATENTS BY ASSIGNEE FROM 2008–JULY 2012 185
CHAPTER 12 DEMAND AND USE 187
CONTRAST AGENTS MARKET 187
REGULATORY ISSUES 187
BABY BOOMER GENERATION 187
INCREASING INCIDENCE OF LIFE-THREATENING DISEASES 187
COMPETITION 188
TECHNOLOGICAL ADVANCEMENTS 188
SETBACKS IN INDUSTRY 188
TRENDS IN THE IMAGING SYSTEMS MARKET 188
CHAPTER 13 COMPANY PROFILES 192
AMAG PHARMACEUTICALS INC. 192
ANALOGIC CORPORATION 192
BAYER HEALTHCARE PHARMACEUTICALS 193
BRACCO IMAGING SPA 193
COVIDIEN 193
ECHOSON SA (PL) 194
ESAOTE S.P.A 194
FONAR CORPORATION 195
GE HEALTHCARE 195
GUERBET LLC 196
HITACHI MEDICAL CORPORATION 196
HOLOGIC INC 197
LANTHEUS MEDICAL IMAGING 197
MILLENIUM TECHNOLOGIES LTD. 197
NORDION 198
PARADIGM MEDICAL INDUSTRIES INC. 198
PARAMED MEDICAL SYSTEMS INC. 199
PHILIPS HEALTHCARE 199
POSITRON CORPORATION 199
SAMSUNG MEDISON AMERICA INC 200
SHIMADZU CORPORATION 200
SIEMENS AG 201
SONOSITE INC 201
TELEMED LTD. 202
TERASON ULTRASOUND 202
TIME MEDICAL INC. 203
TOMTEC IMAGING SYSTEMS 203
TOSHIBA MEDICAL SYSTEMS CORPORATIONS 204
TRIAD ISOTOPES INC. 204
ULTRASONIX MEDICAL CORP. 204
VOLCANO CORPORATION 205
ZONARE MEDICAL SYSTEMS INC. 205
CHAPTER 14 APPENDIX I-ABBREVIATIONS 208

LIST OF TABLES
SUMMARY TABLE GLOBAL REVENUE OF MEDICAL IMAGING MARKET, THROUGH 2017 ($
MILLIONS) 6
TABLE 1 HISTORY AND DEVELOPMENT OF X-RAY IMAGING 9
TABLE 2 ADVANTAGES AND DISADVANTAGES OF X-RAY 11
TABLE 3 HISTORY AND DEVELOPMENT OF ULTRASOUND 12
TABLE 4 ADVANTAGES AND DISADVANTAGES OF ULTRASOUND 14
TABLE 5 HISTORY AND DEVELOPMENT OF MRI 15
TABLE 6 ADVANTAGES AND DISADVANTAGES OF MRI 16
TABLE 7 ADVANTAGES AND DISADVANTAGES OF COMPUTED TOMOGRAPHY 18
TABLE 8 HISTORY AND DEVELOPMENT OF POSITRON EMISSION TECHNOLOGY 19
TABLE 9 ADVANTAGES AND DISADVANTAGES OF PET 20
TABLE 10 DIFFERENCES BETWEEN CT AND MRI 21
TABLE 11 DIFFERENCES BETWEEN CT AND ULTRASOUND 22
TABLE 12 DIFFERENCES BETWEEN CT AND PET 22
TABLE 13 DIFFERENCES BETWEEN MRI AND X-RAY 23
TABLE 14 ADVANTAGES AND DISADVANTAGES OF BARIUM AS CONTRAST MEDIUM 25
TABLE 15 NONSPECIFIC EXTRACELLULAR CONTRAST AGENTS 26
TABLE 16 LIVER-SPECIFIC CONTRAST AGENTS 27
TABLE 17 COMMONLY USED RADIOPHARMACEUTICALS 28
TABLE 18 NEW APPROVAL OF IMAGING SYSTEMS, 2008-AUGUST 2012 35
TABLE 19 510(K) APPROVALS FOR ULTRASOUND SYSTEMS, 2008–AUGUST 2012 36
TABLE 20 510(K) APPROVALS FOR MRI SYSTEMS, 2008-AUGUST 2012 42
TABLE 21 510(K) APPROVALS FOR X-RAY/CT SYSTEMS, 2008–AUGUST 2012 43
TABLE 22 510(K) APPROVALS FOR PET SYSTEMS, 2008–AUGUST 2012 46
TABLE 23 RECALLS FOR MAGNETIC RESONANCE IMAGING SYSTEMS 46
TABLE 24 RECALLS FOR X-RAY AND COMPUTED TOMOGRAPHY SYSTEMS, 2008—SEPTEMBER
2012 48
TABLE 25 RECALLS FOR ULTRASOUND SYSTEMS, 2008-SEPTEMBER 2012 52
TABLE 26 RECALLS FOR PET SYSTEMS, 2008—SEPTEMBER 2012 56
TABLE 27 APPROVAL OF CONTRAST AGENTS 58
TABLE 28 SAFETY ALERTS FOR CONTRAST AGENTS, 2008—SEPTEMBER 2012 59
TABLE 29 NEW DEVELOPMENTS IN CONTRAST AGENTS 62
TABLE 30 NEW DEVELOPMENTS IN COMPUTED TOMOGRAPHY 62
TABLE 31 NEW DEVELOPMENTS IN MAGNETIC RESONANCE IMAGING 63
TABLE 32 NEW DEVELOPMENTS IN POSITRON EMISSION TOMOGRAPHY 63
TABLE 33 NEW DEVELOPMENTS IN ULTRASOUND 64
TABLE 34 NEW DEVELOPMENTS IN RADIOGRAPHY (X-RAY, MAMMOGRAPHY AND
FLUOROSCOPY) 66
TABLE 35 GLOBAL MARKET FOR CONTRAST AGENTS, BY IMAGING TECHNOLOGY, THROUGH
2017 ($ MILLIONS) 71
TABLE 36 GLOBAL MARKET SHARES FOR CONTRAST AGENTS, BY IMAGING TECHNOLOGY
2011 (%) 72
TABLE 37 GLOBAL MARKET FOR IMAGING SYSTEMS, BY IMAGING TECHNOLOGY, THROUGH
2017 ($ MILLIONS) 77
TABLE 38 MARKET SHARE FOR IMAGING SYSTEMS, BY IMAGING TECHNOLOGY, 2011 (%) 78
TABLE 39 GLOBAL MARKET FOR CONTRAST AGENTS, BY REGION, THROUGH 2017 ($
MILLIONS) 81
TABLE 40 GLOBAL MARKET SHARE FOR CONTRAST AGENTS, BY REGION, 2011 (%) 82
TABLE 41 GLOBAL MARKET FOR IMAGING SYSTEMS, BY REGION, THROUGH 2017 ($
MILLIONS) 86
TABLE 42 GLOBAL MARKET SHARES FOR IMAGING SYSTEMS, BY REGION, 2011 (%) 87
TABLE 43 GLOBAL REVENUE FOR IMAGING CONTRAST AGENTS AND SYSTEMS USED FOR
VARIOUS DISEASES, THROUGH 2017 ($ MILLIONS) 92
TABLE 44 GLOBAL REVENUE MARKET SHARE FOR IMAGING CONTRAST AGENTS AND
SYSTEMS USED FOR VARIOUS DISEASES, 2011 (%) 94
TABLE 45 GLOBAL MARKET FOR X-RAY AND CT AGENTS BY REGION, THROUGH 2017 ($
MILLIONS) 98
TABLE 46 MARKET SHARE OF X-RAY AND CT REAGENTS BY REGION, 2011 (%) 99
TABLE 47 GLOBAL MARKET FOR IMAGING SYSTEMS, BY TYPE, THROUGH 2017 ($ MILLIONS) 100
TABLE 48 MARKET SHARE OF IMAGING SYSTEMS BY TYPE, 2011 (%) 101
TABLE 49 GLOBAL MARKET FOR X-RAY SYSTEMS BY REGION, THROUGH 2017 ($ MILLIONS) 104
TABLE 50 MARKET SHARE OF X-RAY SYSTEMS BY REGION, 2011 (%) 105
TABLE 51 GLOBAL MARKET FOR COMPUTED TOMOGRAPHY SYSTEMS BY REGION, THROUGH
2017 ($ MILLIONS) 107
TABLE 52 MARKET SHARE OF COMPUTED TOMOGRAPHY SYSTEMS BY REGION, 2011 (%) 108
TABLE 53 GLOBAL REVENUE FOR X-RAY AND CT REAGENTS AND SYSTEMS USED FOR
VARIOUS DISEASES, THROUGH 2017 ($ MILLIONS) 109
TABLE 54 GLOBAL REVENUE FOR X-RAY AND CT REAGENTS AND SYSTEMS USED FOR
VARIOUS DISEASES, THROUGH 2017 ($ MILLIONS) 112
TABLE 55 X-RAY IMAGING MARKET SHARES, BY APPLICATION, 2011 (%) 113
TABLE 56 GLOBAL REVENUE FOR CT REAGENTS AND SYSTEMS USED FOR VARIOUS
DISEASES, THROUGH 2017 ($ MILLIONS) 115
TABLE 57 COMPUTED TOMOGRAPHY IMAGING MARKET SHARES, BY APPLICATION, 2011 (%) 116
TABLE 58 LEADING MANUFACTURERS OF X-RAY AND COMPUTED TOMOGRAPHY CONTRAST
AGENTS 117
TABLE 59 GLOBAL MARKET SHARES OF X-RAY AND COMPUTED TOMOGRAPHY CONTRAST
AGENTS, 2011 (%) 118
TABLE 60 LEADING MANUFACTURERS OF RADIOGRAPHY (X-RAY, FLUOROSCOPY AND
MAMMOGRAPHY) IMAGING SYSTEMS 119
TABLE 61 GLOBAL MARKET SHARES OF X-RAY IMAGING SYSTEMS, 2011 (%) 122
TABLE 62 LEADING MANUFACTURERS OF COMPUTED TOMOGRAPHY SYSTEMS 123
TABLE 63 WORLDWIDE MARKET SHARES OF COMPUTED TOMOGRAPHY SYSTEMS, 2011 (%) 124
TABLE 64 GLOBAL MARKET FOR MRI AGENTS, BY REGION, THROUGH 2017 ($ MILLIONS) 127
TABLE 65 MARKET SHARE OF MRI REAGENTS BY REGION, 2011 (%) 128
TABLE 66 GLOBAL MARKET FOR MRI SYSTEMS, BY REGION, THROUGH 2017 ($ MILLIONS) 131
TABLE 67 MARKET SHARE OF MRI SYSTEMS, BY REGION, 2011 (%) 132
TABLE 68 GLOBAL MARKET FOR MRI SYSTEMS, BY MAGNETIC STRENGTH, THROUGH 2017 ($
MILLIONS) 134
TABLE 69 GLOBAL REVENUE FOR MRI REAGENTS AND SYSTEMS USED FOR VARIOUS
DISEASES, THROUGH 2017 ($ MILLIONS) 135
TABLE 70 MAGNETIC RESONANCE IMAGING MARKET SHARES, BY APPLICATION, 2011 (%) 137
TABLE 71 LEADING MANUFACTURERS OF MAGNETIC RESONANCE IMAGING CONTRAST
AGENTS 138
TABLE 72 GLOBAL MARKET SHARES OF MRI CONTRAST AGENTS, 2011 (%) 138
TABLE 73 LEADING MANUFACTURERS OF NUCLEAR MAGNETIC IMAGING SYSTEMS 139
TABLE 74 GLOBAL MARKET SHARES OF MRI IMAGING SYSTEMS, 2011 (%) 141
TABLE 75 GLOBAL MARKET FOR ULTRASOUND REAGENTS, BY REGION, THROUGH 2017 ($
MILLIONS) 145
TABLE 76 MARKET SHARE OF ULTRASOUND REAGENTS, BY REGION, 2011 (%) 146
TABLE 77 GLOBAL MARKET FOR ULTRASOUND SYSTEMS BY REGION, THROUGH 2017 ($
MILLIONS) 148
TABLE 78 MARKET SHARE OF ULTRASOUND SYSTEMS, BY REGION, 2011 (%) 149
TABLE 79 GLOBAL REVENUE FOR ULTRASOUND REAGENTS AND SYSTEMS USED FOR
VARIOUS DISEASES, THROUGH 2017 ($ MILLIONS) 151
TABLE 80 ULTRASOUND IMAGING MARKET SHARES, BY APPLICATION, 2011 (%) 152
TABLE 81 LEADING MANUFACTURERS OF ULTRASOUND CONTRAST AGENTS 153
TABLE 82 GLOBAL MARKET SHARES OF ULTRASOUND CONTRAST AGENTS, 2011 (%) 154
TABLE 83 LEADING MANUFACTURERS OF ULTRASOUND IMAGING SYSTEMS 155
TABLE 84 GLOBAL MARKET SHARES OF ULTRASOUND SYSTEMS, 2011 (%) 157
TABLE 85 GLOBAL MARKET FOR DIAGNOSTIC RADIOPHARMACEUTICALS BY REGION,
THROUGH 2017 ($ MILLIONS) 162
TABLE 86 MARKET SHARES OF DIAGNOSTIC RADIOPHARMACEUTICALS BY REGION, 2011 (%) 163
TABLE 87 GLOBAL MARKET FOR PET SYSTEMS, BY REGION, THROUGH 2017 ($ MILLIONS) 165
TABLE 88 MARKET SHARE OF PET SYSTEMS BY REGION, 2011 (%) 166
TABLE 89 GLOBAL REVENUE FOR PET IMAGING USED FOR VARIOUS DISEASES, THROUGH
2017 ($ MILLIONS) 168
TABLE 90 POSITRON EMISSION TOMOGRAPHY IMAGING MARKET SHARES, BY APPLICATION,
2011 (%) 169
TABLE 91 LEADING MANUFACTURERS OF DIAGNOSTIC RADIOPHARMACEUTICALS 171
TABLE 92 WORLDWIDE MARKET SHARES OF DIAGNOSTIC RADIOPHARMACEUTICALS, 2011
(%) 173
TABLE 93 LEADING MANUFACTURERS OF PET IMAGING SYSTEMS 174
TABLE 94 WORLDWIDE MARKET SHARES OF PET IMAGING SYSTEMS, 2011 (%) 175
TABLE 95 TOTAL NUMBER OF PATENTS FOR CONTRAST AGENTS, FROM 2008–JULY 2012 177
TABLE 96 NUMBER OF PATENTS FOR CONTRAST AGENTS BY IMAGING MODALITY, FROM
2008–JULY 2012 178
TABLE 97 NUMBER OF PATENTS BY COMPANY FROM 2008–JULY 2012 178
TABLE 98 NUMBER OF PATENTS BY COUNTRY FROM 2008–JULY 2012 179
TABLE 99 NUMBER OF PATENTS BY ASSIGNEE FROM 2008–JULY 2012 179
TABLE 100 TOTAL NUMBER OF PATENTS FOR IMAGING MODALITIES FROM 2008–JULY 2012 180
TABLE 101 NUMBER OF PATENTS BY IMAGING MODALITY FROM JANUARY 2008–JULY 2012 181
TABLE 102 NUMBER OF PATENTS BY COMPANY FROM 2008–JULY 2012 182
TABLE 103 NUMBER OF PATENTS BY COUNTRY FROM 2008–JULY 2012 184
TABLE 104 NUMBER OF PATENTS BY ASSIGNEE FROM 2008–JULY 2012 185

LIST OF FIGURES
SUMMARY FIGURE GLOBAL REVENUE OF MEDICAL IMAGING MARKET, 2010-2017 ($
MILLIONS) 6
FIGURE 1 GLOBAL MARKET FOR CONTRAST AGENTS, BY IMAGING TECHNOLOGY, 2010–2017
($ MILLIONS) 71
FIGURE 2 GLOBAL MARKET SHARES FOR CONTRAST AGENTS, BY IMAGING TECHNOLOGY,
2011 (%) 72
FIGURE 3 GLOBAL MARKET FOR IMAGING SYSTEMS, BY IMAGING TECHNOLOGY, 2010–2017
($ MILLIONS) 77
FIGURE 4 MARKET SHARE FOR IMAGING SYSTEMS, BY IMAGING TECHNOLOGY, 2011 (%) 78
FIGURE 5 GLOBAL MARKET FOR CONTRAST AGENTS, BY REGION, 2010–2017 ($ MILLIONS) 81
FIGURE 6 GLOBAL MARKET SHARE FOR CONTRAST AGENTS, BY REGION, 2011 (%) 82
FIGURE 7 GLOBAL MARKET FOR IMAGING SYSTEMS, BY REGION, 2010–2017 ($ MILLIONS) 86
FIGURE 8 GLOBAL MARKET SHARE FOR IMAGING SYSTEMS BY REGION, 2011 (%) 87
FIGURE 9 GLOBAL REVENUE FOR IMAGING CONTRAST AGENTS AND SYSTEMS USED FOR
VARIOUS DISEASES, 2010–2017 ($ MILLIONS) 92
FIGURE 10 GLOBAL REVENUE MARKET SHARE FOR IMAGING CONTRAST AGENTS AND
SYSTEMS USED FOR VARIOUS DISEASES, 2011 (%) 94
FIGURE 11 GLOBAL MARKET FOR X-RAY AND CT AGENTS BY REGION, 2010-2017 ($ MILLIONS) 98
FIGURE 12 MARKET SHARE OF X-RAY AND CT REAGENTS BY REGION, 2011 (%) 99
FIGURE 13 GLOBAL MARKET FOR IMAGING SYSTEMS, BY TYPE, THROUGH 2017 ($ MILLIONS) 100
FIGURE 14 MARKET SHARE OF IMAGING SYSTEMS BY TYPE, 2011 (%) 101
FIGURE 15 GLOBAL MARKET FOR X-RAY SYSTEMS BY REGION, 2010-2017 ($ MILLIONS) 104
FIGURE 16 MARKET SHARE OF X-RAY SYSTEMS BY REGION, 2011 (%) 105
FIGURE 17 GLOBAL MARKET FOR COMPUTED TOMOGRAPHY SYSTEMS BY REGION,
2010-2017 ($ MILLIONS) 107
FIGURE 18 MARKET SHARE OF COMPUTED TOMOGRAPHY SYSTEMS BY REGION, 2011 (%) 109
FIGURE 19 GLOBAL REVENUE FOR X-RAY AND CT REAGENTS AND SYSTEMS USED FOR
VARIOUS DISEASES, 2010-2017 ($ MILLIONS) 109
FIGURE 20 GLOBAL REVENUE FOR X-RAY REAGENTS AND SYSTEMS USED FOR VARIOUS
DISEASES, 2010-2017 ($ MILLIONS) 112
FIGURE 21 X-RAY IMAGING MARKET SHARES, BY APPLICATION, 2011 (%) 113
FIGURE 22 GLOBAL REVENUE FOR CT REAGENTS AND SYSTEMS USED FOR VARIOUS
DISEASES, 2010-2017 ($ MILLIONS) 115
FIGURE 23 COMPUTED TOMOGRAPHY IMAGING MARKET SHARES, BY APPLICATION, 2011 (%) 116
FIGURE 24 GLOBAL MARKET SHARES OF X-RAY AND COMPUTED TOMOGRAPHY CONTRAST
AGENTS, 2011 (%) 118
FIGURE 25 GLOBAL MARKET SHARES OF X-RAY IMAGING SYSTEMS, 2011 (%) 122
FIGURE 26 WORLDWIDE MARKET SHARES OF COMPUTED TOMOGRAPHY SYSTEMS, 2011 (%) 124
FIGURE 27 GLOBAL MARKET FOR MRI AGENTS, BY REGION, 2010-2017 ($ MILLIONS) 127
FIGURE 28 MARKET SHARE OF MRI REAGENTS BY REGION, 2011 (%) 128
FIGURE 29 GLOBAL MARKET FOR MRI SYSTEMS, BY REGION, 2010-2017 ($ MILLIONS) 132
FIGURE 30 MARKET SHARE OF MRI SYSTEMS, BY REGION, 2011 (%) 132
FIGURE 31 GLOBAL MARKET FOR MRI SYSTEMS, BY MAGNETIC STRENGTH, 2010-2017 ($
MILLIONS) 134
FIGURE 32 GLOBAL REVENUE FOR MRI REAGENTS AND SYSTEMS USED FOR VARIOUS
DISEASES, 2010-2017 ($ MILLIONS) 135
FIGURE 33 MAGNETIC RESONANCE IMAGING MARKET SHARES, BY APPLICATION, 2011 (%) 137
FIGURE 34 GLOBAL MARKET SHARES OF MRI CONTRAST AGENTS, 2011 (%) 138
FIGURE 35 GLOBAL MARKET SHARES OF MRI IMAGING SYSTEMS, 2011 (%) 141
FIGURE 36 GLOBAL MARKET FOR ULTRASOUND REAGENTS, BY REGION, 2010-2017
(MILLIONS) 145
FIGURE 37 MARKET SHARE OF ULTRASOUND REAGENTS, BY REGION, 2011 (%) 146
FIGURE 38 GLOBAL MARKET FOR ULTRASOUND SYSTEMS BY REGION, 2010-2017 ($
MILLIONS) 148
FIGURE 39 MARKET SHARE OF ULTRASOUND SYSTEMS, BY REGION, 2011 (%) 149
FIGURE 40 GLOBAL REVENUE FOR ULTRASOUND REAGENTS AND SYSTEMS USED FOR
VARIOUS DISEASES, 2010-2017 ($ MILLIONS) 152
FIGURE 41 ULTRASOUND IMAGING MARKET SHARES, BY APPLICATION, 2011 (%) 152
FIGURE 42 GLOBAL MARKET SHARES OF ULTRASOUND CONTRAST AGENTS, 2011 (%) 154
FIGURE 43 GLOBAL MARKET SHARES OF ULTRASOUND SYSTEMS, 2011 (%) 158
FIGURE 44 GLOBAL MARKET FOR DIAGNOSTIC RADIOPHARMACEUTICALS BY REGION,
2010-2017 ($ MILLIONS) 162
FIGURE 45 MARKET SHARE OF DIAGNOSTIC RADIOPHARMACEUTICALS BY REGION, 2011 (%) 163
FIGURE 46 GLOBAL MARKET FOR PET SYSTEMS, BY REGION, 2010-2017 ($ MILLIONS) 165
FIGURE 47 MARKET SHARE OF PET SYSTEMS BY REGION, 2011 (%) 166
FIGURE 48 GLOBAL REVENUE FOR PET IMAGING USED FOR VARIOUS DISEASES, 2010-2017
($ MILLIONS) 168
FIGURE 49 POSITRON EMISSION TOMOGRAPHY IMAGING MARKET SHARES, BY
APPLICATION, 2011 (%) 169
FIGURE 50 WORLDWIDE MARKET SHARES OF DIAGNOSTIC RADIOPHARMACEUTICALS, 2011
(%) 173
FIGURE 51 WORLDWIDE MARKET SHARES OF PET IMAGING SYSTEMS, 2011 (%) 175
FIGURE 52 TOTAL NUMBER OF PATENTS FOR IMAGING MOD

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