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Emerging Diagnostic Technologies in the Changing U.S. Market

  • January 2013
  • -
  • BCC Research
  • -
  • 121 pages

INTRODUCTION

STUDY BACKGROUND

The U.S. market for medical diagnostic products and services has been growing strongly in recent years, driven by favorable reimbursement policies for clinical lab testing, increasing awareness of the need for early disease detection and the health needs of an increasingly elderly population. Another factor driving the diagnostic market has been the development of new diagnostic technologies that open the way to new applications, while increasing the accuracy, reliability and relative comfort of existing applications.

GOALS AND OBJECTIVES

The overall goal of this study is to provide the reader with an up-to-date understanding of the emerging diagnostic technologies that will influence the future size and structure of the market for medical diagnostics. Specific objectives include the following:

Identifying the new diagnostic technologies with the greatest potential to influence the diagnostic market in the near to mid-term (2012 to 2017).
Analyzing the key drivers and constraints that will shape the market for these technologies over the next five years.
Estimating the current and future demand for each of these technologies through 2017.

INTENDED AUDIENCE

The report is intended especially for vendors of medical diagnostic devices and services, as well as government agencies, healthcare policy analysts and others seeking to understand the medical applications of new diagnostic technologies. Although the report focuses on specific technologies, it is largely nontechnical in nature. That is, it is concerned less with theory and jargon than with what works and how much of it the market is likely to purchase.

As such, the report’s main audience is executive management, marketing and financial analysts. It is not written specifically for scientists and technologists, although its findings concerned the market for their work, including the availability of government and corporate research funding for different technologies and applications.

SCOPE AND FORMAT

This report addresses the U.S. market for emerging diagnostic technologies. Of course, terms such as emerging or new are relative in a rapidly evolving market such as medical diagnostics. Thus, this report pragmatically defines emerging diagnostic technologies as those that are only in limited commercial use and/or in advanced development as of 2012. Also included are certain technologies, such as telemedicine, that have been in use for more than a few years, but which have the potential today to cause a fundamental or paradigm shift in the way diagnoses are performed. The technologies covered fall into the following categories:

Ultrasound.
Magnetic resonance imaging.
Nuclear medicine.
Computed tomography.
Photonics, optics and spectroscopy.
Hybrid imaging technologies.
Telediagnosis.
Laboratory information systems.
Diagnostic decision support systems.
Imaging agents.
Terahertz technology.
Wireless devices.
Other technologies.

The format of the study includes the following elements:

Summary.
Definitions.
Developments in enabling technologies.
Key end-user segments.
Market environment (legal and regulatory, standards, trends in the healthcare industry, demographic and economic trends, other market drivers and barriers to deployment).
Emerging diagnostic technologies and products.
Detailed market estimates and projections, by type of diagnostic technology and product, 2011 to 2017.
Supplier profiles.
Patent analysis.

METHODOLOGY

Both primary and secondary research methodologies were used in preparing this research report. The findings and conclusions of this report are based on information gathered from developers, vendors, integrators and users of medical diagnostic devices. Interview data were combined with information gathered through an extensive review of secondary sources such as trade publications, trade associations, company literature and online databases to produce the baseline market estimates contained in this report.

The base year for analysis and projection is 2011. With 2011 as a baseline, market projections were developed for 2012 to 2017. The projections are based on a combination of a consensus among the primary contacts combined with BCC’s understanding of the key market drivers and their impact from historical and analytical perspectives.

The specific assumptions and approach that BCC used to develop the projections (both near/mid-term and long-term) for each application are documented in detail under the various segments addressed. This way, readers can see how the market estimates were developed and, if they so desire, test the impact on the final numbers of changing assumptions regarding such matters as date of regulatory approval.

One of the approaches used by BCC deserves special mention here. Particularly in the case of diagnostic technologies that have not yet reached the market, BCC used the sales performance of existing technologies that share some of the same functions or other characteristics as emerging diagnostic technology in question as a benchmark for assessing the latter’s sales potential.

All dollar projections presented in this report are in 2011 constant U.S. dollars.

AUTHOR'S CREDENTIALS

The author of this report is Andrew McWilliams. Mr. McWilliams, a partner in the Boston-based international technology and marketing consulting firm 43rd Parallel, LLC, is the author of several other BCC Research studies of the healthcare and related industries, including HLC016D Microelectronic Medical Implants: Products, Technologies and Opportunities; HLC036D Medical Robotics and Computer-Assisted Surgery: The Global Market; HLC042A Radiation-based Therapy and Therapeutic Imaging; HLC051F The Market for Minimally Invasive Medical Devices; HLC038C Patient Monitoring; HLC054B Home Medical Equipment: Technologies and Global Markets; HLC014E Global Markets for Telemedicine Technologies; HLC048C Healthcare Information Technology; HLC066B Medical Automation Technologies, Products and Markets; HLC070A Preventive Healthcare Technologies, Products and Markets; and HLC072B Global Markets and Technologies for Medical Lasers.

Table Of Contents

Emerging Diagnostic Technologies in the Changing U.S. Market
TABLE OF CONTENTS

CHAPTER 1 INTRODUCTION 1
STUDY BACKGROUND 1
GOALS AND OBJECTIVES 1
INTENDED AUDIENCE 1
SCOPE AND FORMAT 1
METHODOLOGY 2
AUTHOR'S CREDENTIALS 3
RELATED BCC RESEARCH 3
BCC ON-LINE SERVICES 3
DISCLAIMER 4
CHAPTER 2 SUMMARY 6
SUMMARY TABLE U.S. MARKET FOR EMERGING DIAGNOSTIC TECHNOLOGIES, THROUGH
2017 ($ MILLIONS) 6
SUMMARY FIGURE U.S. MARKET FOR EMERGING DIAGNOSTIC TECHNOLOGIES, THROUGH
2017 ($ MILLIONS) 6
CHAPTER 3 OVERVIEW 9
DEFINITIONS 9
DIAGNOSTIC TECHNOLOGIES 9
EMERGING TECHNOLOGIES 9
ENABLING TECHNOLOGIES 9
AUTOMATION/ROBOTICS 10
Automated Health Assessment and Monitoring 10
Automated Imaging and Image Analysis 10
Automated Laboratory Testing and Analysis 10
WIRELESS COMMUNICATIONS AND NETWORKING 11
Improved Sensors 11
Data Access and Sharing 11
Remote Diagnostics 12
ADVANCED SENSORS 12
Parameters Measured 12
Micro- and Nanosensors 13
Sensing Fabrics and Wearable Monitors 13
ARTIFICIAL INTELLIGENCE 14
END-USER SEGMENTS 15
HOSPITALS 15
FIGURE 1 TREND IN THE NUMBER OF U.S. HOSPITALS, 1995-2010 (UNITS) 15
PHYSICIAN PRACTICES 16
FIGURE 2 TREND IN THE NUMBER OF ACTIVE U.S. PHYSICIANS, 2002-2009 (THOUSANDS) 16
TABLE 1 DISTRIBUTION OF U.S. PHYSICIANS BY PRACTICE SETTING/SIZE, 1996-2008 (%) 17
HOME CARE 17
FIGURE 3 TRENDS IN U.S. EXPENDITURES ON HOME HEALTHCARE, 2000-2010 ($ BILLIONS) 18
MILITARY 18
FIGURE 4 U.S. MILITARY HEALTH EXPENDITURES, FY 2000-FY 2011 ($ BILLIONS) 18
MEDICAL RESEARCH/CLINICAL LABORATORIES 19
EMERGING DIAGNOSTIC TECHNOLOGIES AND PRODUCTS 20
TABLE 2 EMERGING DIAGNOSTIC TECHNOLOGIES 20
ULTRASOUND 20
MAGNETIC RESONANCE IMAGING 21
NUCLEAR MEDICINE 21
COMPUTED TOMOGRAPHY 21
PHOTONICS, OPTICS AND SPECTROSCOPY 21
HYBRID IMAGING TECHNOLOGIES 22
TELEDIAGNOSIS 22
LABORATORY INFORMATION SYSTEMS 22
DIAGNOSTIC DECISION SUPPORT SYSTEMS 22
IMAGING AGENTS 22
TERAHERTZ TECHNOLOGY 23
WIRELESS DEVICES 23
OTHER TECHNOLOGIES 23
MARKET SUMMARY 23
TECHNOLOGY SEGMENTS 23
TABLE 3 U.S. MARKET FOR EMERGING DIAGNOSTIC TECHNOLOGIES, THROUGH 2017 ($
MILLIONS) 24
LEADING PRODUCTS 24
TABLE 4 NEW DIAGNOSTIC PRODUCTS EXPECTED TO SHOW LARGEST GAINS IN DOLLAR
SALES, 2011-2017 ($ MILLIONS) 25
CHAPTER 4 MARKET ENVIRONMENT 27
LEGAL/REGULATORY ENVIRONMENT 27
U.S. FOOD AND DRUG ADMINISTRATION 27
MEDICARE/MEDICAID 29
PATIENT PROTECTION AND AFFORDABLE CARE ACT 29
ECONOMIC TRENDS 30
DEMOGRAPHIC TRENDS 31
OVERALL POPULATION GROWTH 31
TABLE 5 TRENDS IN TOTAL U.S. POPULATION, THROUGH 2017 (MILLION PEOPLE) 31
INCREASE IN THE NUMBER OF ELDERLY PEOPLE 31
TABLE 6 U.S. POPULATION AGED 65 YEARS AND OLDER, THROUGH 2017 (MILLION PEOPLE) 31
EPIDEMIOLOGICAL TRENDS 31
CARDIOVASCULAR DISEASE 32
TABLE 7 HOSPITALIZATIONS, PHYSICIAN OFFICE VISITS AND DEATHS DUE TO HEART
DISEASE IN THE U.S., 2009 32
CANCER 32
TRENDS IN THE HEALTHCARE INDUSTRY 33
RISING COSTS 33
FIGURE 5 TRENDS IN U.S. PER CAPITA HEALTHCARE COSTS, 1990-2010 ($ PER PERSON) 33
DECLINING REIMBURSEMENT RATES 34
SHORTAGES OF HEALTHCARE PERSONNEL/INCREASING WORKLOADS 34
Physicians 34
Nurses 34
CHAPTER 5 INTELLECTUAL PROPERTY 36
FIGURE 6 U.S. PATENTS RELATING TO EMERGING DIAGNOSTIC TECHNOLOGIES (NUMBER
OF PATENTS /% OF TOTAL PATENTS/) 36
FIGURE 7 U.S. PATENTS RELATING TO EMERGING DIAGNOSTIC TECHNOLOGIES (% OF
TOTAL PATENTS/NUMBER OF PATENTS) 38
CHAPTER 6 EMERGING ULTRASOUND TECHNOLOGIES 40
SUMMARY 40
TECHNOLOGIES 40
AUTOMATED BREAST ULTRASOUND 40
ROBOTIC ULTRASOUND 41
REMOTE ULTRASOUND 41
CURRENT STATUS 42
MARKET ASSESSMENT 42
TABLE 8 U.S. MARKET FOR EMERGING DIAGNOSTIC ULTRASOUND TECHNOLOGIES,
THROUGH 2017 ($ MILLIONS) 43
FIGURE 8 TRENDS IN U.S. DIAGNOSTIC ULTRASOUND MARKET, 2011-2017 ($ MILLIONS) 43
AUTOMATED BREAST ULTRASOUND 43
TABLE 9 U.S. MARKET FOR AUTOMATED BREAST ULTRASOUND, THROUGH 2017 ($
MILLIONS) 44
ROBOTIC AND REMOTE ULTRASOUND 44
TABLE 10 U.S. MARKET FOR REMOTE AND ROBOTIC DIAGNOSTIC ULTRASOUND, THROUGH
2017 ($ MILLIONS) 44
CHAPTER 7 EMERGING MRI TECHNOLOGIES 46
SUMMARY 46
TECHNOLOGIES 46
COMPUTER-ASSISTED MRI DETECTION 46
ULTRA-LOW FIELD MRI 47
MAGNETOENCEPHALOGRAPHY 47
CURRENT STATUS 48
MARKET ASSESSMENT 49
TABLE 11 U.S. MARKET FOR EMERGING DIAGNOSTIC MRI TECHNOLOGIES, THROUGH 2017
($ MILLIONS) 49
FIGURE 9 TRENDS IN U.S. DIAGNOSTIC MRI MARKET, 2011-2017 ($ MILLIONS) 49
COMPUTER-ASSISTED DIAGNOSTIC MRI 50
TABLE 12 U.S. MARKET FOR COMPUTER-ASSISTED DIAGNOSTIC MRI TECHNOLOGIES,
THROUGH 2017 ($ MILLIONS) 50
ULTRA-LOW FIELD MRI AND MRI/MEG 50
TABLE 13 U.S. MARKET FOR EMERGING DIAGNOSTIC MRI TECHNOLOGIES, THROUGH 2017
($ MILLIONS) 51
CHAPTER 8 EMERGING NUCLEAR MEDICINE DIAGNOSTIC TECHNOLOGIES 53
SUMMARY 53
TECHNOLOGIES 53
PETRRA 53
HANDHELD GAMMA CAMERAS 53
CURRENT STATUS 54
MARKET ASSESSMENT 54
TABLE 14 U.S. MARKET FOR EMERGING NUCLEAR MEDICINE DIAGNOSTIC TECHNOLOGIES,
THROUGH 2017 ($ MILLIONS) 55
FIGURE 10 TRENDS IN U.S. MARKET FOR EMERGING NUCLEAR MEDICINE DIAGNOSTIC
TECHNOLOGIES, 2011-2017 ($ MILLIONS) 55
PETTRA 55
TABLE 15 U.S. MARKET FOR PETTRA DEVICES, THROUGH 2017 ($ MILLIONS) 55
HANDHELD GAMMA CAMERAS 56
TABLE 16 U.S. MARKET FOR HANDHELD GAMMA CAMERAS, THROUGH 2017 ($ MILLIONS) 56
CHAPTER 9 EMERGING TOMOGRAPHIC DIAGNOSTIC TECHNOLOGIES 58
SUMMARY 58
TECHNOLOGIES 58
VIRTUAL COLONOSCOPY 58
DIGITAL TOMOSYNTHESIS 59
CURRENT STATUS 59
MARKET ASSESSMENT 60
TABLE 17 U.S. MARKET FOR EMERGING TOMOGRAPHIC DIAGNOSTIC TECHNOLOGIES,
THROUGH 2017 ($ MILLIONS) 60
FIGURE 11 TRENDS IN U.S. MARKET FOR EMERGING TOMOGRAPHIC DIAGNOSTIC
TECHNOLOGIES, 2011-2017 ($ MILLIONS) 60
VIRTUAL COLONOSCOPY 61
TABLE 18 U.S. MARKET FOR VIRTUAL COLONOSCOPY SOFTWARE AND CAD SYSTEMS,
THROUGH 2017 ($ MILLIONS) 61
BREAST TOMOSYNTHESIS 62
TABLE 19 U.S. MARKET FOR BREAST TOMOSYNTHESIS SYSTEMS, THROUGH 2017 ($
MILLIONS) 62
CHAPTER 10 DEVELOPMENTS IN PHOTONICS, OPTICS AND SPECTROSCOPY 64
SUMMARY 64
TECHNOLOGIES 64
QUANTUM DOTS 64
NEAR-INFRARED SPECTROSCOPY 65
SPATIALLY RESOLVED SPECTROSCOPY 65
OPTICAL COHERENCE TOMOGRAPHY 65
CURRENT STATUS 66
MARKET ASSESSMENT 66
TABLE 20 U.S. MARKET FOR EMERGING PHOTONIC, OPTICAL AND SPECTROSCOPIC
DIAGNOSTIC TECHNOLOGIES, THROUGH 2017 ($ MILLIONS) 67
FIGURE 12 TRENDS IN U.S. MARKET FOR EMERGING PHOTONIC, OPTICAL AND
SPECTROSCOPIC DIAGNOSTIC TECHNOLOGIES, 2011-2017 ($ MILLIONS) 67
QUANTUM DOTS 67
TABLE 21 U.S. MARKET FOR QUANTUM DOTS USED IN DIAGNOSTIC APPLICATIONS,
THROUGH 2017 ($ MILLIONS) 68
NEAR INFRARED 68
TABLE 22 U.S. MARKET FOR NIR DIAGNOSTIC DEVICES, THROUGH 2017 ($ MILLIONS) 68
OPTICAL COHERENCE TOMOGRAPHY 68
TABLE 23 U.S. MARKET FOR OCT DIAGNOSTIC DEVICES, THROUGH 2017 ($ MILLIONS) 69
CHAPTER 11 DEVELOPMENTS IN HYBRID TECHNOLOGIES 71
SUMMARY 71
TECHNOLOGIES 71
PET/MRI 71
PHOTOACOUSTIC TOMOGRAPHY 72
CURRENT STATUS 72
MARKET ASSESSMENT 72
TABLE 24 U.S. MARKET FOR EMERGING HYBRID DIAGNOSTIC TECHNOLOGIES, THROUGH
2017 ($ MILLIONS) 73
FIGURE 13 TRENDS IN U.S. MARKET FOR EMERGING HYBRID DIAGNOSTIC TECHNOLOGIES,
2011-2017 ($ MILLIONS) 73
PET/MRI 73
TABLE 25 U.S. MARKET FOR PET/MRI SCANNERS, THROUGH 2017 ($ MILLIONS) 74
PHOTOACOUSTIC TOMOGRAPHY 74
TABLE 26 U.S. MARKET FOR PAT SCANNERS, THROUGH 2017 ($ MILLIONS) 74
CHAPTER 12 EMERGING TELEDIAGNOSTIC TECHNOLOGIES 76
SUMMARY 76
TECHNOLOGIES 76
VIDEOCONFERENCING 76
REAL-TIME, STORE-AND-FORWARD AND HYBRID TELECONFERENCING 77
IP-BASED VIDEOCONFERENCING 77
PERIPHERAL DEVICES 77
CURRENT STATUS 78
MARKET ASSESSMENT 78
TABLE 27 U.S. MARKET FOR TELEDIAGNOSTIC TECHNOLOGIES, THROUGH 2017 ($
MILLIONS) 78
FIGURE 14 TRENDS IN U.S. MARKET FOR TELEDIAGNOSTIC TECHNOLOGIES, 2011-2017 ($
MILLIONS) 78
VIDEOCONFERENCING 79
TABLE 28 U.S. MARKET FOR TELEMEDICINE VIDEOCONFERENCING EQUIPMENT,
THROUGH 2017 ($ MILLIONS) 79
PERIPHERALS 79
TABLE 29 U.S. MARKET FOR TELEMEDICINE VIDEOCONFERENCING PERIPHERAL DEVICES,
THROUGH 2017 ($ MILLIONS) 80
CHAPTER 13 DEVELOPMENTS IN LABORATORY INFORMATION SYSTEMS 82
SUMMARY 82
TECHNOLOGIES 82
INTEROPERABILITY ISSUES 82
DATA STANDARDS 83
CURRENT STATUS 83
MARKET ASSESSMENT 84
TABLE 30 U.S. MARKET FOR DIAGNOSTIC LIS, THROUGH 2017 ($ MILLIONS) 84
FIGURE 15 TRENDS IN U.S. MARKET FOR DIAGNOSTIC LIS, 2011-2017 ($ MILLIONS) 84
CHAPTER 14 DEVELOPMENTS IN DIAGNOSTIC DECISION SUPPORT SYSTEMS 87
SUMMARY 87
TECHNOLOGIES 87
KNOWLEDGE-BASED SYSTEMS 87
Expert Systems 87
Probabilistic Systems 89
Bayesian Network 89
Heuristic Systems 89
NON-KNOWLEDGE-BASED SYSTEMS 90
Artificial Neural Networks 90
Genetic Algorithms 91
CURRENT STATUS 91
MARKET ASSESSMENT 92
TABLE 31 U.S. MARKET FOR DIAGNOSTIC DECISION SUPPORT SYSTEMS, THROUGH 2017 ($
MILLIONS) 92
FIGURE 16 TRENDS IN U.S. MARKET FOR DIAGNOSTIC DECISION SUPPORT SYSTEMS,
2011-2017 ($ MILLIONS) 93
CHAPTER 15 DEVELOPMENTS IN IMAGING AGENTS 95
SUMMARY 95
TECHNOLOGIES 95
SUPERPARAMAGNETIC MRI CONTRAST AGENTS 95
APTAMERS 96
NANOPARTICLE-BASED OPTICAL IMAGING AGENTS 96
NANOSHELLS 97
CURRENT STATUS 97
MARKET ASSESSMENT 97
TABLE 32 U.S. MARKET FOR EMERGING DIAGNOSTIC IMAGING AGENTS, THROUGH 2017 ($
MILLIONS) 97
FIGURE 17 TRENDS IN U.S. MARKET FOR EMERGING DIAGNOSTIC IMAGING AGENTS,
2011â??2017 ($ MILLIONS) 98
SUPERPARAMAGNETIC MRI CONTRAST AGENTS 99
TABLE 33 U.S. MARKET FOR SUPERPARAMAGNETIC MRI CONTRAST AGENTS, THROUGH
2017 ($ MILLIONS) 99
HYPERPOLARIZED IMAGING AGENTS 99
TABLE 34 U.S. MARKET FOR HYPERPOLARIZED MRI CONTRAST AGENTS, THROUGH 2017 ($
MILLIONS) 100
APTAMERS 100
TABLE 35 U.S. MARKET FOR APTAMER-BASED IMAGING AGENTS, THROUGH 2017 ($
MILLIONS) 100
OTHER NANOPARTICLE-BASED OPTICAL IMAGING AGENTS 100
TABLE 36 U.S. MARKET FOR NANOPARTICLE-BASED OPTICAL IMAGING AGENTS, THROUGH
2017 ($ MILLIONS) 101
NANOSHELLS 101
TABLE 37 U.S. MARKET FOR NANOSHELL-BASED OPTICAL IMAGING AGENTS, THROUGH
2017 ($ MILLIONS) 101
CHAPTER 16 EMERGING DIAGNOSTIC APPLICATIONS OF THZ RADIATION 103
SUMMARY 103
TECHNOLOGIES 103
DIGITAL DERMOSCOPES 103
ENDOSCOPES 104
THZ TOMOGRAPHIC INSTRUMENTS 105
THZ BIOCHIPS 105
CURRENT STATUS 105
MARKET ASSESSMENT 106
TABLE 38 U.S. MARKET FOR DIAGNOSTIC APPLICATIONS OF THZ RADIATION, THROUGH
2017 ($ MILLIONS) 106
FIGURE 18 TRENDS IN U.S. MARKET FOR EMERGING TERAHERTZ DIAGNOSTIC
TECHNOLOGIES, 2011-2017 ($ MILLIONS) 107
DIGITAL DERMOSCOPES 107
TABLE 39 U.S. MARKET FOR TERAHERTZ SKIN CANCER IMAGING EQUIPMENT, THROUGH
2017 ($ MILLIONS) 107
ENDOSCOPES 107
TABLE 40 U.S. MARKET FOR TERAHERTZ ENDOSCOPES, THROUGH 2017 ($ MILLIONS) 108
TOMOGRAPHIC INSTRUMENTS 108
TABLE 41 U.S. MARKET FOR TERAHERTZ BURN DIAGNOSTIC INSTRUMENTS THROUGH
2017 ($ MILLIONS) 108
THZ BIOCHIPS 109
TABLE 42 U.S. MARKET FOR TERAHERTZ BIOCHIPS USED IN MEDICAL DIAGNOSTICS
APPLICATIONS, THROUGH 2017 ($ MILLIONS) 109
CHAPTER 17 DEVELOPMENTS IN WIRELESS DIAGNOSTIC DEVICES 111
SUMMARY 111
TECHNOLOGIES 111
NFC-ENABLED MOBILE DIAGNOSTIC DEVICES 111
CAPSULE ENDOSCOPY 112
CURRENT STATUS 113
MARKET ASSESSMENT 113
TABLE 43 U.S. MARKET FOR EMERGING WIRELESS DIAGNOSTIC TECHNOLOGIES,
THROUGH 2017 ($ MILLIONS) 113
FIGURE 19 TRENDS IN U.S. MARKET FOR EMERGING WIRELESS DIAGNOSTIC
TECHNOLOGIES, 2011-2017 ($ MILLIONS) 114
NFC-ENABLED MOBILE DEVICE DIAGNOSTICS 114
TABLE 44 U.S. MARKET FOR NFC-ENABLED MOBILE DEVICE DIAGNOSTICS, THROUGH 2017
($ MILLIONS) 115
CAPSULE ENDOSCOPY SYSTEMS 115
TABLE 45 U.S. MARKET FOR CAPSULE ENDOSCOPY SYSTEMS, THROUGH 2017 ($ MILLIONS) 115
CHAPTER 18 OTHER EMERGING DIAGNOSTIC TECHNOLOGIES 117
SUMMARY 117
TECHNOLOGIES 117
"ELECTRONIC NOSES" 117
DENDRIMER-BASE D DIAGNOSTIC REAGENTS 118
CURRENT STATUS 118
MARKET ASSESSMENT 118
TABLE 46 U.S. MARKET FOR OTHER EMERGING DIAGNOSTIC TECHNOLOGIES, THROUGH
2017 ($ MILLIONS) 118
FIGURE 20 TRENDS IN U.S. MARKET OTHER EMERGING DIAGNOSTIC TECHNOLOGIES,
2011-2017 ($ MILLIONS) 118
ELECTRONIC NOSES 119
TABLE 47 U.S. MARKET FOR DIAGNOSTIC ELECTRONIC NOSES, THROUGH 2017 ($
MILLIONS) 119
DENDRIMER-BASED REAGENTS 119
TABLE 48 U.S. MARKET FOR DENDRIMER-BASED DIAGNOSTIC REAGENTS, THROUGH 2017
($ MILLIONS) 120
CHAPTER 19 APPENDIX A: COMPANY PROFILES 122
ULTRASOUND TECHNOLOGIES 122
HELIX MEDICAL SYSTEMS, LTD. 122
TECHNISCAN MEDICAL SYSTEMS 122
U-SYSTEMS, INC. 122
MRI TECHNOLOGIES 123
ICAD INC. 123
INVIVO CORP. 123
MERGE HEALTHCARE 123
TOMOGRAPHIC AND NUCLEAR MEDICINE TECHNOLOGIES 124
CRYSTAL PHOTONICS GMBH 124
HOLOGIC 124
HYBRIDYNE IMAGING TECHNOLOGIES 124
INTRAMEDICAL IMAGING LLC 125
PETRRA LTD. 125
PHOTONIC, OPTICAL AND SPECTROSCOPIC TECHNOLOGIES 125
CARL ZEISS MEDITEC AG 125
EVIDENT TECHNOLOGIES 125
HEIDELBERG ENGINEERING 126
INFRAREDX, INC. 126
INFRASCAN INC. 127
LIFE TECHNOLOGIES CORP. 127
TOMOPHASE CORP. 128
HYBRID TECHNOLOGIES 128
ENDRA, INC. 128
VISUALSONICS, INC. 128
TELEDIAGNOSTIC TECHNOLOGIES 129
GLOBALMEDIA GROUP LLC 129
INTERNATIONAL BUSINESS MACHINES CORP. 129
INTOUCH TECHNOLOGIES 129
POLYCOM 130
ROCHE DIAGNOSTICS 130
SIEMENS HEALTHCARE 130
LABORATORY INFORMATION SYSTEMS 131
COMPUGROUP MEDICAL - LAB DIVISION 131
MCKESSON CORP. 131
CLINICAL DECISION SUPPORT SYSTEMS 131
ISABEL HEALTHCARE INC. 131
LIFECOM, INC. 132
LOGICAL IMAGES, INC. 132
MASSACHUSETTS GENERAL HOSPITAL 132
MEDRX 133
ONTOLOGY WORKS, INC. 133
PROBLEM-KNOWLEDGE COUPLERS 133
IMAGING AGENTS AND RADIATION PROBES 134
BAYER SCHERING PHARMA AG 134
NANOSPECTRA BIOSCIENCES, INC. 134
PERKINELMER, INC. 135
XEMED LLC 135
TERAHERTZ IMAGING APPLICATIONS 136
CANON INC. 136
M SQUARED LASERS LTD. 136
SPIRE CORP. 136
TERASENSE DEVELOPMENT LABS LLC 137
VERISANTE TECHNOLOGY INC. 137
WIRELESS AND NETWORKED DEVICES 137
GENTAG, INC. 137
GIVEN IMAGING, LTD. 138
OTHER TECHNOLOGIES 138
SIEMENS HEALTHCARE 138

LIST OF TABLES
SUMMARY TABLE U.S. MARKET FOR EMERGING DIAGNOSTIC TECHNOLOGIES, THROUGH
2017 ($ MILLIONS) 6
TABLE 1 DISTRIBUTION OF U.S. PHYSICIANS BY PRACTICE SETTING/SIZE, 1996-2008 (%) 17
TABLE 2 EMERGING DIAGNOSTIC TECHNOLOGIES 20
TABLE 3 U.S. MARKET FOR EMERGING DIAGNOSTIC TECHNOLOGIES, THROUGH 2017 ($
MILLIONS) 24
TABLE 4 NEW DIAGNOSTIC PRODUCTS EXPECTED TO SHOW LARGEST GAINS IN DOLLAR
SALES, 2011-2017 ($ MILLIONS) 25
TABLE 5 TRENDS IN TOTAL U.S. POPULATION, THROUGH 2017 (MILLION PEOPLE) 31
TABLE 6 U.S. POPULATION AGED 65 YEARS AND OLDER, THROUGH 2017 (MILLION PEOPLE) 31
TABLE 7 HOSPITALIZATIONS, PHYSICIAN OFFICE VISITS AND DEATHS DUE TO HEART
DISEASE IN THE U.S., 2009 32
TABLE 8 U.S. MARKET FOR EMERGING DIAGNOSTIC ULTRASOUND TECHNOLOGIES,
THROUGH 2017 ($ MILLIONS) 43
TABLE 9 U.S. MARKET FOR AUTOMATED BREAST ULTRASOUND, THROUGH 2017 ($
MILLIONS) 44
TABLE 10 U.S. MARKET FOR REMOTE AND ROBOTIC DIAGNOSTIC ULTRASOUND, THROUGH
2017 ($ MILLIONS) 44
TABLE 11 U.S. MARKET FOR EMERGING DIAGNOSTIC MRI TECHNOLOGIES, THROUGH 2017
($ MILLIONS) 49
TABLE 12 U.S. MARKET FOR COMPUTER-ASSISTED DIAGNOSTIC MRI TECHNOLOGIES,
THROUGH 2017 ($ MILLIONS) 50
TABLE 13 U.S. MARKET FOR EMERGING DIAGNOSTIC MRI TECHNOLOGIES, THROUGH 2017
($ MILLIONS) 51
TABLE 14 U.S. MARKET FOR EMERGING NUCLEAR MEDICINE DIAGNOSTIC TECHNOLOGIES,
THROUGH 2017 ($ MILLIONS) 55
TABLE 15 U.S. MARKET FOR PETTRA DEVICES, THROUGH 2017 ($ MILLIONS) 55
TABLE 16 U.S. MARKET FOR HANDHELD GAMMA CAMERAS, THROUGH 2017 ($ MILLIONS) 56
TABLE 17 U.S. MARKET FOR EMERGING TOMOGRAPHIC DIAGNOSTIC TECHNOLOGIES,
THROUGH 2017 ($ MILLIONS) 60
TABLE 18 U.S. MARKET FOR VIRTUAL COLONOSCOPY SOFTWARE AND CAD SYSTEMS,
THROUGH 2017 ($ MILLIONS) 61
TABLE 19 U.S. MARKET FOR BREAST TOMOSYNTHESIS SYSTEMS, THROUGH 2017 ($
MILLIONS) 62
TABLE 20 U.S. MARKET FOR EMERGING PHOTONIC, OPTICAL AND SPECTROSCOPIC
DIAGNOSTIC TECHNOLOGIES, THROUGH 2017 ($ MILLIONS) 67
TABLE 21 U.S. MARKET FOR QUANTUM DOTS USED IN DIAGNOSTIC APPLICATIONS,
THROUGH 2017 ($ MILLIONS) 68
TABLE 22 U.S. MARKET FOR NIR DIAGNOSTIC DEVICES, THROUGH 2017 ($ MILLIONS) 68
TABLE 23 U.S. MARKET FOR OCT DIAGNOSTIC DEVICES, THROUGH 2017 ($ MILLIONS) 69
TABLE 24 U.S. MARKET FOR EMERGING HYBRID DIAGNOSTIC TECHNOLOGIES, THROUGH
2017 ($ MILLIONS) 73
TABLE 25 U.S. MARKET FOR PET/MRI SCANNERS, THROUGH 2017 ($ MILLIONS) 74
TABLE 26 U.S. MARKET FOR PAT SCANNERS, THROUGH 2017 ($ MILLIONS) 74
TABLE 27 U.S. MARKET FOR TELEDIAGNOSTIC TECHNOLOGIES, THROUGH 2017 ($
MILLIONS) 78
TABLE 28 U.S. MARKET FOR TELEMEDICINE VIDEOCONFERENCING EQUIPMENT, THROUGH
2017 ($ MILLIONS) 79
TABLE 29 U.S. MARKET FOR TELEMEDICINE VIDEOCONFERENCING PERIPHERAL DEVICES,
THROUGH 2017 ($ MILLIONS) 80
TABLE 30 U.S. MARKET FOR DIAGNOSTIC LIS, THROUGH 2017 ($ MILLIONS) 84
TABLE 31 U.S. MARKET FOR DIAGNOSTIC DECISION SUPPORT SYSTEMS, THROUGH 2017 ($
MILLIONS) 92
TABLE 32 U.S. MARKET FOR EMERGING DIAGNOSTIC IMAGING AGENTS, THROUGH 2017 ($
MILLIONS) 97
TABLE 33 U.S. MARKET FOR SUPERPARAMAGNETIC MRI CONTRAST AGENTS, THROUGH
2017 ($ MILLIONS) 99
TABLE 34 U.S. MARKET FOR HYPERPOLARIZED MRI CONTRAST AGENTS, THROUGH 2017 ($
MILLIONS) 100
TABLE 35 U.S. MARKET FOR APTAMER-BASED IMAGING AGENTS, THROUGH 2017 ($
MILLIONS) 100
TABLE 36 U.S. MARKET FOR NANOPARTICLE-BASED OPTICAL IMAGING AGENTS, THROUGH
2017 ($ MILLIONS) 101
TABLE 37 U.S. MARKET FOR NANOSHELL-BASED OPTICAL IMAGING AGENTS, THROUGH
2017 ($ MILLIONS) 101
TABLE 38 U.S. MARKET FOR DIAGNOSTIC APPLICATIONS OF THZ RADIATION, THROUGH
2017 ($ MILLIONS) 106
TABLE 39 U.S. MARKET FOR TERAHERTZ SKIN CANCER IMAGING EQUIPMENT, THROUGH
2017 ($ MILLIONS) 107
TABLE 40 U.S. MARKET FOR TERAHERTZ ENDOSCOPES, THROUGH 2017 ($ MILLIONS) 108
TABLE 41 U.S. MARKET FOR TERAHERTZ BURN DIAGNOSTIC INSTRUMENTS THROUGH 2017
($ MILLIONS) 108
TABLE 42 U.S. MARKET FOR TERAHERTZ BIOCHIPS USED IN MEDICAL DIAGNOSTICS
APPLICATIONS, THROUGH 2017 ($ MILLIONS) 109
TABLE 43 U.S. MARKET FOR EMERGING WIRELESS DIAGNOSTIC TECHNOLOGIES, THROUGH
2017 ($ MILLIONS) 113
TABLE 44 U.S. MARKET FOR NFC-ENABLED MOBILE DEVICE DIAGNOSTICS, THROUGH 2017
($ MILLIONS) 115
TABLE 45 U.S. MARKET FOR CAPSULE ENDOSCOPY SYSTEMS, THROUGH 2017 ($ MILLIONS) 115
TABLE 46 U.S. MARKET FOR OTHER EMERGING DIAGNOSTIC TECHNOLOGIES, THROUGH
2017 ($ MILLIONS) 118
TABLE 47 U.S. MARKET FOR DIAGNOSTIC ELECTRONIC NOSES, THROUGH 2017 ($ MILLIONS) 119
TABLE 48 U.S. MARKET FOR DENDRIMER-BASED DIAGNOSTIC REAGENTS, THROUGH 2017 ($
MILLIONS) 120

LIST OF FIGURES
SUMMARY FIGURE U.S. MARKET FOR EMERGING DIAGNOSTIC TECHNOLOGIES, THROUGH
2017 ($ MILLIONS) 6
FIGURE 1 TREND IN THE NUMBER OF U.S. HOSPITALS, 1995-2010 (UNITS) 15
FIGURE 2 TREND IN THE NUMBER OF ACTIVE U.S. PHYSICIANS, 2002-2009 (THOUSANDS) 16
FIGURE 3 TRENDS IN U.S. EXPENDITURES ON HOME HEALTHCARE, 2000-2010 ($ BILLIONS) 18
FIGURE 4 U.S. MILITARY HEALTH EXPENDITURES, FY 2000-FY 2011 ($ BILLIONS) 18
FIGURE 5 TRENDS IN U.S. PER CAPITA HEALTHCARE COSTS, 1990-2010 ($ PER PERSON) 33
FIGURE 6 U.S. PATENTS RELATING TO EMERGING DIAGNOSTIC TECHNOLOGIES (NUMBER
OF PATENTS /% OF TOTAL PATENTS/) 36
FIGURE 7 U.S. PATENTS RELATING TO EMERGING DIAGNOSTIC TECHNOLOGIES (% OF
TOTAL PATENTS/NUMBER OF PATENTS) 38
FIGURE 8 TRENDS IN U.S. DIAGNOSTIC ULTRASOUND MARKET, 2011-2017 ($ MILLIONS) 43
FIGURE 9 TRENDS IN U.S. DIAGNOSTIC MRI MARKET, 2011-2017 ($ MILLIONS) 49
FIGURE 10 TRENDS IN U.S. MARKET FOR EMERGING NUCLEAR MEDICINE DIAGNOSTIC
TECHNOLOGIES, 2011-2017 ($ MILLIONS) 55
FIGURE 11 TRENDS IN U.S. MARKET FOR EMERGING TOMOGRAPHIC DIAGNOSTIC
TECHNOLOGIES, 2011-2017 ($ MILLIONS) 60
FIGURE 12 TRENDS IN U.S. MARKET FOR EMERGING PHOTONIC, OPTICAL AND
SPECTROSCOPIC DIAGNOSTIC TECHNOLOGIES, 2011-2017 ($ MILLIONS) 67
FIGURE 13 TRENDS IN U.S. MARKET FOR EMERGING HYBRID DIAGNOSTIC TECHNOLOGIES,
2011-2017 ($ MILLIONS) 73
FIGURE 14 TRENDS IN U.S. MARKET FOR TELEDIAGNOSTIC TECHNOLOGIES, 2011-2017 ($
MILLIONS) 78
FIGURE 15 TRENDS IN U.S. MARKET FOR DIAGNOSTIC LIS, 2011-2017 ($ MILLIONS) 84
FIGURE 16 TRENDS IN U.S. MARKET FOR DIAGNOSTIC DECISION SUPPORT SYSTEMS,
2011-2017 ($ MILLIONS) 93
FIGURE 17 TRENDS IN U.S. MARKET FOR EMERGING DIAGNOSTIC IMAGING AGENTS,
2011â??2017 ($ MILLIONS) 98
FIGURE 18 TRENDS IN U.S. MARKET FOR EMERGING TERAHERTZ DIAGNOSTIC
TECHNOLOGIES, 2011-2017 ($ MILLIONS) 107
FIGURE 19 TRENDS IN U.S. MARKET FOR EMERGING WIRELESS DIAGNOSTIC
TECHNOLOGIES, 2011-2017 ($ MILLIONS) 114
FIGURE 20 TRENDS IN U.S. MARKET OTHER EMERGING DIAGNOSTIC TECHNOLOGIES,
2011-2017 ($ MILLIONS) 118

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