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Metastatic Prostate Cancer - Pipeline Review, H1 2015

  • January 2015
  • -
  • Global Markets Direct
  • -
  • 84 pages

Metastatic Prostate Cancer - Pipeline Review, H1 2015

Summary

Global Markets Direct’s, ‘Metastatic Prostate Cancer - Pipeline Review, H1 2015’, provides an overview of the Metastatic Prostate Cancer’s therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Metastatic Prostate Cancer, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Metastatic Prostate Cancer and special features on late-stage and discontinued projects.

Global Markets Direct’s report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct’s proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct’s team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope

- The report provides a snapshot of the global therapeutic landscape of Metastatic Prostate Cancer
- The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities
- The report reviews key players involved in the therapeutics development for Metastatic Prostate Cancer and enlists all their major and minor projects
- The report summarizes all the dormant and discontinued pipeline projects
- A review of the Metastatic Prostate Cancer products under development by companies and universities/research institutes based on information derived from company and industry-specific sources
- Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages
- A detailed assessment of monotherapy and combination therapy pipeline projects
- Coverage of the Metastatic Prostate Cancer pipeline on the basis of target, MoA, route of administration and molecule type
- Latest news and deals relating related to pipeline products

Reasons to buy

- Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies
- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
- Develop strategic initiatives by understanding the focus areas of leading companies
- Identify and understand important and diverse types of therapeutics under development for Metastatic Prostate Cancer
- Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline
- Devise corrective measures for pipeline projects by understanding Metastatic Prostate Cancer pipeline depth and focus of Indication therapeutics
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
- Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline

Table Of Contents

Metastatic Prostate Cancer - Pipeline Review, H1 2015
Table of Contents
Introduction 7
Global Markets Direct Report Coverage 7
Metastatic Prostate Cancer Overview 8
Therapeutics Development 9
Pipeline Products for Metastatic Prostate Cancer - Overview 9
Pipeline Products for Metastatic Prostate Cancer - Comparative Analysis 10
Metastatic Prostate Cancer - Therapeutics under Development by Companies 11
Metastatic Prostate Cancer - Therapeutics under Investigation by Universities/Institutes 13
Metastatic Prostate Cancer - Pipeline Products Glance 14
Late Stage Products 14
Clinical Stage Products 15
Early Stage Products 16
Metastatic Prostate Cancer - Products under Development by Companies 17
Metastatic Prostate Cancer - Products under Investigation by Universities/Institutes 18
Metastatic Prostate Cancer - Companies Involved in Therapeutics Development 19
Actinium Pharmaceuticals, Inc. 19
Camurus AB 20
Colby Pharmaceutical Company 21
Eli Lilly and Company 22
Fountain Biopharma Inc. 23
Johnson and Johnson 24
MedImmune, LLC 25
MEI Pharma, Inc. 26
OncoMax 27
OXiGENE, Inc. 28
Progenics Pharmaceuticals, Inc. 29
ValiRx Plc 30
Metastatic Prostate Cancer - Therapeutics Assessment 31
Assessment by Monotherapy Products 31
Assessment by Target 32
Assessment by Mechanism of Action 34
Assessment by Route of Administration 36
Assessment by Molecule Type 38
Drug Profiles 40
abiraterone acetate - Drug Profile 40
Product Description 40
Mechanism of Action 40
RandD Progress 40
Actimab-P - Drug Profile 43
Product Description 43
Mechanism of Action 43
RandD Progress 43
CADD-522 - Drug Profile 44
Product Description 44
Mechanism of Action 44
RandD Progress 44
Cell Therapy to Target PSMA for Metastatic Prostate Cancer - Drug Profile 45
Product Description 45
Mechanism of Action 45
RandD Progress 45
CPC-410 - Drug Profile 46
Product Description 46
Mechanism of Action 46
RandD Progress 46
FB-704A - Drug Profile 47
Product Description 47
Mechanism of Action 47
RandD Progress 47
KGP-94 - Drug Profile 48
Product Description 48
Mechanism of Action 48
RandD Progress 48
leuprolide acetate - Drug Profile 49
Product Description 49
Mechanism of Action 49
RandD Progress 49
LU-901 - Drug Profile 50
Product Description 50
Mechanism of Action 50
RandD Progress 50
LY-2495655 - Drug Profile 51
Product Description 51
Mechanism of Action 51
RandD Progress 51
MEDI-6469 - Drug Profile 52
Product Description 52
Mechanism of Action 52
RandD Progress 52
MIP-1095 - Drug Profile 54
Product Description 54
Mechanism of Action 54
RandD Progress 54
MVI-118 - Drug Profile 55
Product Description 55
Mechanism of Action 55
RandD Progress 55
OMRCA-01 - Drug Profile 56
Product Description 56
Mechanism of Action 56
RandD Progress 56
pracinostat - Drug Profile 58
Product Description 58
Mechanism of Action 58
RandD Progress 58
Recombinant Protein for Oncology - Drug Profile 60
Product Description 60
Mechanism of Action 60
RandD Progress 60
VAC-1 - Drug Profile 61
Product Description 61
Mechanism of Action 61
RandD Progress 61
Vaccine For Oncolytic Newcastle Disease Virus - Drug Profile 63
Product Description 63
Mechanism of Action 63
RandD Progress 63
VAL-201 - Drug Profile 64
Product Description 64
Mechanism of Action 64
RandD Progress 64
Metastatic Prostate Cancer - Recent Pipeline Updates 65
Metastatic Prostate Cancer - Dormant Projects 75
Metastatic Prostate Cancer - Discontinued Products 76
Metastatic Prostate Cancer - Product Development Milestones 77
Featured News and Press Releases 77
Mar 27, 2014: OXiGENE Announces Presentation of Preclinical Abstracts at 2014 AACR Conference 77
Feb 06, 2014: ZYTIGA Now Reimbursed in Quebec for Use Prior to Chemotherapy in Men with Metastatic Prostate Cancer 77
Nov 21, 2013: ZYTIGA Now Available for Men with Metastatic Prostate Cancer in British Columbia Prior to Chemotherapy 78
May 29, 2013: Janssen's Zytiga Receives New Indication Approval From Health Canada For Treatment Of Metastatic Prostate Cancer 78
Jun 02, 2012: Zytiga's Phase III Results Show Significant Improvement In Radiographic Progression-Free Survival And Trend For Increased Overall Survival In Metastatic Prostate Cancer Patients 80
May 16, 2012: JandJ's ZYTIGA Now Available For Eligible Patients In Nova Scotia, Newfoundland And Labrador For Prostate Cancer 81
Mar 04, 2005: Geron Announces Publication Of Phase 1-2 Telomerase Vaccine Study Results In Patients With Metastatic Prostate Cancer 81
Appendix 83
Methodology 83
Coverage 83
Secondary Research 83
Primary Research 83
Expert Panel Validation 83
Contact Us 84
Disclaimer 84

List of Tables

Number of Products under Development for Metastatic Prostate Cancer, H1 2015 9
Number of Products under Development for Metastatic Prostate Cancer - Comparative Analysis, H1 2015 10
Number of Products under Development by Companies, H1 2015 12
Number of Products under Investigation by Universities/Institutes, H1 2015 13
Comparative Analysis by Late Stage Development, H1 2015 14
Comparative Analysis by Clinical Stage Development, H1 2015 15
Comparative Analysis by Early Stage Development, H1 2015 16
Products under Development by Companies, H1 2015 17
Products under Investigation by Universities/Institutes, H1 2015 18
Metastatic Prostate Cancer - Pipeline by Actinium Pharmaceuticals, Inc., H1 2015 19
Metastatic Prostate Cancer - Pipeline by Camurus AB, H1 2015 20
Metastatic Prostate Cancer - Pipeline by Colby Pharmaceutical Company, H1 2015 21
Metastatic Prostate Cancer - Pipeline by Eli Lilly and Company, H1 2015 22
Metastatic Prostate Cancer - Pipeline by Fountain Biopharma Inc., H1 2015 23
Metastatic Prostate Cancer - Pipeline by Johnson and Johnson, H1 2015 24
Metastatic Prostate Cancer - Pipeline by MedImmune, LLC, H1 2015 25
Metastatic Prostate Cancer - Pipeline by MEI Pharma, Inc., H1 2015 26
Metastatic Prostate Cancer - Pipeline by OncoMax, H1 2015 27
Metastatic Prostate Cancer - Pipeline by OXiGENE, Inc., H1 2015 28
Metastatic Prostate Cancer - Pipeline by Progenics Pharmaceuticals, Inc., H1 2015 29
Metastatic Prostate Cancer - Pipeline by ValiRx Plc, H1 2015 30
Assessment by Monotherapy Products, H1 2015 31
Number of Products by Stage and Target, H1 2015 33
Number of Products by Stage and Mechanism of Action, H1 2015 35
Number of Products by Stage and Route of Administration, H1 2015 37
Number of Products by Stage and Molecule Type, H1 2015 39
Metastatic Prostate Cancer Therapeutics - Recent Pipeline Updates, H1 2015 65
Metastatic Prostate Cancer - Dormant Projects, H1 2015 75
Metastatic Prostate Cancer - Discontinued Products, H1 2015 76

List of Figures

Number of Products under Development for Metastatic Prostate Cancer, H1 2015 9
Number of Products under Development for Metastatic Prostate Cancer - Comparative Analysis, H1 2015 10
Number of Products under Development by Companies, H1 2015 11
Number of Products under Investigation by Universities/Institutes, H1 2015 13
Comparative Analysis by Clinical Stage Development, H1 2015 15
Comparative Analysis by Early Stage Products, H1 2015 16
Assessment by Monotherapy Products, H1 2015 31
Number of Products by Top 10 Targets, H1 2015 32
Number of Products by Stage and Top 10 Targets, H1 2015 32
Number of Products by Top 10 Mechanism of Actions, H1 2015 34
Number of Products by Stage and Top 10 Mechanism of Actions, H1 2015 35
Number of Products by Top 10 Routes of Administration, H1 2015 36
Number of Products by Stage and Top 10 Routes of Administration, H1 2015 36
Number of Products by Top 10 Molecule Types, H1 2015 38
Number of Products by Stage and Top 10 Molecule Types, H1 2015 38

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