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Colitis - Pipeline Review, H1 2016

  • February 2016
  • -
  • Global Markets Direct
  • -
  • 103 pages

Colitis - Pipeline Review, H1 2016

Summary

Global Markets Direct’s, ‘Colitis - Pipeline Review, H1 2016’, provides an overview of the Colitis pipeline landscape.

The report provides comprehensive information on the therapeutics under development for Colitis, complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The report also covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases. Additionally, the report provides an overview of key players involved in therapeutic development for Colitis and features dormant and discontinued projects.

Global Markets Direct’s report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Drug profiles featured in the report undergoes periodic review following a stringent set of processes to ensure that all the profiles are updated with the latest set of information. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.

The report helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data.

Scope

- The report provides a snapshot of the global therapeutic landscape of Colitis
- The report reviews pipeline therapeutics for Colitis by companies and universities/research institutes based on information derived from company and industry-specific sources
- The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages
- The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities
- The report reviews key players involved Colitis therapeutics and enlists all their major and minor projects
- The report assesses Colitis therapeutics based on drug target, mechanism of action (MoA), route of administration (RoA) and molecule type
- The report summarizes all the dormant and discontinued pipeline projects
- The report reviews latest news related to pipeline therapeutics for Colitis

Reasons to buy

- Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies
- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
- Identify and understand important and diverse types of therapeutics under development for Colitis
- Identify potential new clients or partners in the target demographic
- Develop strategic initiatives by understanding the focus areas of leading companies
- Plan mergers and acquisitions effectively by identifying key players and it’s most promising pipeline therapeutics
- Devise corrective measures for pipeline projects by understanding Colitis pipeline depth and focus of Indication therapeutics
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
- Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline

Table Of Contents

Colitis - Pipeline Review, H1 2016
Table of Contents
Table of Contents 2
List of Tables 7
List of Figures 8
Introduction 9
Global Markets Direct Report Coverage 9
Colitis Overview 10
Therapeutics Development 11
Pipeline Products for Colitis - Overview 11
Pipeline Products for Colitis - Comparative Analysis 12
Colitis - Therapeutics under Development by Companies 13
Colitis - Therapeutics under Investigation by Universities/Institutes 15
Colitis - Pipeline Products Glance 16
Late Stage Products 16
Clinical Stage Products 17
Early Stage Products 18
Colitis - Products under Development by Companies 19
Colitis - Products under Investigation by Universities/Institutes 20
Colitis - Companies Involved in Therapeutics Development 21
Aerpio Therapeutics, Inc. 21
Ajinomoto Pharmaceuticals Co., Ltd. 22
Akebia Therapeutics, Inc. 23
Amorepacific Corporation 24
Bayer AG 25
Bristol-Myers Squibb Company 26
Dr. Falk Pharma GmbH 27
Galapagos NV 28
Immuron Limited 29
Innate Pharma S.A. 30
Peptinov SAS 31
Pfizer Inc. 32
Prokarium Limited 33
Protalix BioTherapeutics, Inc. 34
RDD Pharma Ltd. 35
Saniona AB 36
Synovo GmbH 37
Colitis - Therapeutics Assessment 38
Assessment by Monotherapy Products 38
Assessment by Target 39
Assessment by Mechanism of Action 41
Assessment by Route of Administration 43
Assessment by Molecule Type 45
Drug Profiles 47
AcTMP-1 - Drug Profile 47
Product Description 47
Mechanism of Action 47
RandD Progress 47
AKB-4924 - Drug Profile 48
Product Description 48
Mechanism of Action 48
RandD Progress 48
AKB-6899 - Drug Profile 49
Product Description 49
Mechanism of Action 49
RandD Progress 49
AN-346 - Drug Profile 50
Product Description 50
Mechanism of Action 50
RandD Progress 50
Antibodies to Inhibit Heparanase for Cancer - Drug Profile 51
Product Description 51
Mechanism of Action 51
RandD Progress 51
Antibody for Colitis - Drug Profile 52
Product Description 52
Mechanism of Action 52
RandD Progress 52
Antisense RNAi Oligonucleotides to Inhibit TNFalpha for Inflammatory Diseases and Colitis - Drug Profile 53
Product Description 53
Mechanism of Action 53
RandD Progress 53
APY-0201 - Drug Profile 54
Product Description 54
Mechanism of Action 54
RandD Progress 54
BC-1215 - Drug Profile 55
Product Description 55
Mechanism of Action 55
RandD Progress 55
BMS-986104 - Drug Profile 56
Product Description 56
Mechanism of Action 56
RandD Progress 56
budesonide - Drug Profile 57
Product Description 57
Mechanism of Action 57
RandD Progress 57
Clostridium difficile vaccine - Drug Profile 60
Product Description 60
Mechanism of Action 60
RandD Progress 60
CSY-0073 - Drug Profile 61
Product Description 61
Mechanism of Action 61
RandD Progress 61
Drugs to Antagonize TRP Channel for Inflammatory Diseases and Colitis - Drug Profile 62
Product Description 62
Mechanism of Action 62
RandD Progress 62
etanercept biosimilar - Drug Profile 63
Product Description 63
Mechanism of Action 63
RandD Progress 63
filgotinib - Drug Profile 64
Product Description 64
Mechanism of Action 64
RandD Progress 64
IMM-124E - Drug Profile 67
Product Description 67
Mechanism of Action 67
RandD Progress 67
IPH-33 - Drug Profile 69
Product Description 69
Mechanism of Action 69
RandD Progress 69
mesalamine - Drug Profile 70
Product Description 70
Mechanism of Action 70
RandD Progress 70
NK-007 - Drug Profile 72
Product Description 72
Mechanism of Action 72
RandD Progress 72
PAC-14028 - Drug Profile 73
Product Description 73
Mechanism of Action 73
RandD Progress 73
Peptide to Inhibit NFkB for Colitis and Enteritis - Drug Profile 75
Product Description 75
Mechanism of Action 75
RandD Progress 75
PF-06425090 - Drug Profile 76
Product Description 76
Mechanism of Action 76
RandD Progress 76
PPV-06 - Drug Profile 77
Product Description 77
Mechanism of Action 77
RandD Progress 77
RDD-2007 - Drug Profile 78
Product Description 78
Mechanism of Action 78
RandD Progress 78
Recombinant Protein to Inhibit TNF-Alpha for Crohn's Disease and Colitis - Drug Profile 79
Product Description 79
Mechanism of Action 79
RandD Progress 79
Small Molecule for Colitis - Drug Profile 80
Product Description 80
Mechanism of Action 80
RandD Progress 80
Synthetic Peptides to Inhibit Panx1 for Colitis - Drug Profile 81
Product Description 81
Mechanism of Action 81
RandD Progress 81
Vaccine to Target Interleukin 12 and Interleukin 23 for Colitis - Drug Profile 82
Product Description 82
Mechanism of Action 82
RandD Progress 82
Vaccine to Target Interleukin-23 for Colitis - Drug Profile 83
Product Description 83
Mechanism of Action 83
RandD Progress 83
ZK-216348 - Drug Profile 84
Product Description 84
Mechanism of Action 84
RandD Progress 84
Colitis - Recent Pipeline Updates 85
Colitis - Dormant Projects 97
Colitis - Discontinued Products 100
Colitis - Product Development Milestones 101
Featured News and Press Releases 101
Jul 11, 2013: Mylan Confirms First-to-File Patent Challenge Relating to CANASA 101
Appendix 102
Methodology 102
Coverage 102
Secondary Research 102
Primary Research 102
Expert Panel Validation 102
Contact Us 102
Disclaimer 103

List of Tables
Number of Products under Development for Colitis, H1 2016 11
Number of Products under Development for Colitis - Comparative Analysis, H1 2016 12
Number of Products under Development by Companies, H1 2016 14
Number of Products under Investigation by Universities/Institutes, H1 2016 15
omparative Analysis by Late Stage Development, H1 2016 16
Comparative Analysis by Clinical Stage Development, H1 2016 17
Comparative Analysis by Early Stage Development, H1 2016 18
Products under Development by Companies, H1 2016 19
Products under Investigation by Universities/Institutes, H1 2016 20
Colitis - Pipeline by Aerpio Therapeutics, Inc., H1 2016 21
Colitis - Pipeline by Ajinomoto Pharmaceuticals Co., Ltd., H1 2016 22
Colitis - Pipeline by Akebia Therapeutics, Inc., H1 2016 23
Colitis - Pipeline by Amorepacific Corporation, H1 2016 24
Colitis - Pipeline by Bayer AG, H1 2016 25
Colitis - Pipeline by Bristol-Myers Squibb Company, H1 2016 26
Colitis - Pipeline by Dr. Falk Pharma GmbH, H1 2016 27
Colitis - Pipeline by Galapagos NV, H1 2016 28
Colitis - Pipeline by Immuron Limited, H1 2016 29
Colitis - Pipeline by Innate Pharma S.A., H1 2016 30
Colitis - Pipeline by Peptinov SAS, H1 2016 31
Colitis - Pipeline by Pfizer Inc., H1 2016 32
Colitis - Pipeline by Prokarium Limited, H1 2016 33
Colitis - Pipeline by Protalix BioTherapeutics, Inc., H1 2016 34
Colitis - Pipeline by RDD Pharma Ltd., H1 2016 35
Colitis - Pipeline by Saniona AB, H1 2016 36
Colitis - Pipeline by Synovo GmbH, H1 2016 37
Assessment by Monotherapy Products, H1 2016 38
Number of Products by Stage and Target, H1 2016 40
Number of Products by Stage and Mechanism of Action, H1 2016 42
Number of Products by Stage and Route of Administration, H1 2016 44
Number of Products by Stage and Molecule Type, H1 2016 46
Colitis Therapeutics - Recent Pipeline Updates, H1 2016 85
Colitis - Dormant Projects, H1 2016 97
Colitis - Dormant Projects (Contd..1), H1 2016 98
Colitis - Dormant Projects (Contd..2), H1 2016 99
Colitis - Discontinued Products, H1 2016 100

List of Figures
Number of Products under Development for Colitis, H1 2016 11
Number of Products under Development for Colitis - Comparative Analysis, H1 2016 12
Number of Products under Development by Companies, H1 2016 13
Number of Products under Investigation by Universities/Institutes, H1 2016 15
Comparative Analysis by Clinical Stage Development, H1 2016 17
Comparative Analysis by Early Stage Products, H1 2016 18
Assessment by Monotherapy Products, H1 2016 38
Number of Products by Top 10 Targets, H1 2016 39
Number of Products by Stage and Top 10 Targets, H1 2016 39
Number of Products by Top 10 Mechanism of Actions, H1 2016 41
Number of Products by Stage and Top 10 Mechanism of Actions, H1 2016 41
Number of Products by Routes of Administration, H1 2016 43
Number of Products by Stage and Routes of Administration, H1 2016 43
Number of Products by Top 10 Molecule Types, H1 2016 45
Number of Products by Stage and Top 10 Molecule Types, H1 2016 45

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