REPORT SCOPE

INTRODUCTION

STUDY OBJECTIVES

BCC’s goal in conducting this study is to provide an overview of the current and future characteristics of the global markets and technologies for molecular, nanoscale and atomic imaging. The key objective is to present the future direction and comprehensive analysis for the molecular, nanoscale and atomic imaging technologies markets, and their positions in the overall global imaging market.

This report explores present and future strategies within the global markets and technologies for molecular, nanoscale and atomic imaging, including the electron and ion microscope market, the imaging probes market, the scanning probe market and the optical and thermal imaging market. The improvisation of the market, the setbacks and the needs of the market are discussed in this report. The comparisons, usage and the advantages and disadvantages of different types of technologies related to molecular, nanoscale and atomic imaging are also portrayed in this report.

A detailed analysis based on the global markets and technologies of molecular, nanoscale and atomic imaging’s industry structure has also been conducted. Revenues are broken down by type, application and region. Sales figures are estimated for the five-year period from 2012 through 2017.

Applications for the different technologies associated with molecular, nanoscale and atomic imaging are also discussed separately in the report, with emphasis of the usage of the molecular, nanoscale and atomic imaging in various commercial and industrial fields. The report also covers significant patents and their allotments in each category.

REASONS FOR DOING THIS STUDY

Extensive research in the fields of molecular, nanoscale and atomic imaging has allowed for an overall growth in the technological advancements in the markets. This has led to the availability and accessibility of high-resolution imaging modalities.

R&D spending, along with increasing competition, patent expiries and new technologies are directing this in a new direction. The overall revenue for the market has seen a steady increase from 2010 to 2012 mainly due to new advancements, new product launches and to meet the demands of new end-user industries. This study looks at almost all of the systems affected by these factors.

Acquisition strategies and collaborations by companies are also covered in this report. This study also discusses the strengths and weaknesses of each type/ technology in light of new technologies, growing competition and changing customer needs.

CONTRIBUTIONS OF THE STUDY AND INTENDED AUDIENCE

This study contributes to the areas of market growth in the overall area of imaging modalities, including molecular, nanoscale and atomic imaging markets. It also contributes to specific areas of market growth within the imaging market including the electron and ion microscope market, the imaging probes market, the scanning probe market and the optical and thermal imaging market. Pharmaceutical biotechnical companies, research institutes and physicians will find this study to be of interest.

SCOPE OF THE STUDY

The scope of this study encompasses the global markets and technologies of the molecular, nanoscale and atomic imaging markets in pharmaceutical and biotechnology markets. BCC analyzes each market and its applications, regulatory environment, technology involved, market projections and market share. Technological issues include the latest trends and developments. The emerging market for molecular, nanoscale and atomic imaging includes countries such as India, China, Japan, Korea, Taiwan, Africa, Australia and New Zealand.

METHODOLOGY

BCC conducted a comprehensive literature search, which included technical newsletters and journals, and many other sources. Data were collected through interviews and correspondence with manufacturers and technical experts of molecular, nanoscale and atomic imaging. Projections were based on estimates such as the current number of end users, potential end users, mergers and acquisitions, and market trends.

INFORMATION SOURCES

Many companies within the industry were surveyed to obtain data for this study. Included were manufacturers and end users of molecular, nanoscale and atomic imaging. Data were gathered from various industry sources. BCC spoke with officials within the industry and consulted newsletters, company literature, product literature and a host of technical articles, journals, indexes and abstracts. Exhaustive investigations of databases by key terminology were completed. In addition, data were compiled from current financial, trade and government sources.

ABOUT THE AUTHOR

The study has been carried out by a team of professionals in the biotechnology industry. The project manager for this project was Shalini S. Dewan, who holds a master’s degree in pharmaceutical chemistry and has over 14 years of industry experience. Among the research topics she has covered are studies on compounds of potential pharmaceutical interest from ibuprofen and 2-naphthyl acetic acid. Shalini was awarded a Gold Medal by the Prime Minister of India for her work and has worked with top companies in India and in the U.S. Some of her other reports with BCC are: Reagents for Chromatography; Spectroscopy: An Enduring Market; Advanced Drug Delivery Systems: Technologies and Global Markets; Orthopedic Drugs, Implants and Devices; Medical Imaging Reagents and Analysis Equipment; Pharmaceutical Regulatory Industry; The Dynamic Media, Sera and Reagent Market in Biotechnology; Contract Pharmaceutical Manufacturing, Research and Packaging: Global Markets; Chiral Technology: Global Markets; Autacoids and Related Drugs: Technologies and Global Markets; Contraceptives: Technologies and Global Markets; Liver Disease Treatments: The Global Market; Hormone Replacement Therapies and Other Hormone Therapies: Global Markets; Cardiovascular Medicine: Diagnostics, Drugs and Devices; and Cancer Therapies: Technologies and Global Markets.

The lead consultant for this project was Dr. Kapil A. Setia, who holds a doctoral degree in life sciences. She has a number of research publications in her credit, including her thesis, which was given an award of excellence.

REPORT HIGHLIGHTS

This report provides:
• An overview of the global market for molecular, nanoscale, and atomic imaging.
• Analyses of global market trends, with data from 2010 through 2012, and projections of compound annual growth rates (CAGRs) through 2017.
• Descriptions of imaging equipment and technologies for examining materials, electronics, and biological samples.
• Coverage of technological issues, including novel molecular, nanometer, and atomic imaging capabilities.
• Examination of research activities and areas of interest related to imaging applications.
• Comprehensive company profiles of major players.

Table Of Contents

TABLE OF CONTENTS

CHAPTER 1 INTRODUCTION 2

STUDY OBJECTIVES 2
REASONS FOR DOING THIS STUDY 2
CONTRIBUTIONS OF THE STUDY AND INTENDED AUDIENCE 3
SCOPE OF THE STUDY 3
METHODOLOGY 3
INFORMATION SOURCES 3
ABOUT THE AUTHOR 3
RELATED BCC RESEARCH REPORTS 4
BCC ONLINE SERVICES 4
DISCLAIMER 5

CHAPTER 2 EXECUTIVE SUMMARY 7

SUMMARY TABLE GLOBAL REVENUE OF MOLECULAR, ATOMIC AND
NANOSCALE IMAGING, THROUGH 2017 ($ MILLIONS) 8
SUMMARY FIGURE GLOBAL REVENUE OF MOLECULAR, ATOMIC AND
NANOSCALE IMAGING, 2010-2017 ($ MILLIONS) 8

CHAPTER 3 OVERVIEW 10

DEFINITIONS 10
HISTORY AND DEVELOPMENT OF IMAGING TECHNIQUES 11
TABLE 1 HISTORY AND DEVELOPMENT OF IMAGING TECHNIQUES 12
CLASSIFICATION OF IMAGING TECHNIQUES 13
OPTICAL AND THERMAL IMAGING 13
Bioluminescent and Fluorescent Microscopy 14
Fluorescent and Bioluminescence Proteins 14
Applications of Fluorescent Proteins 15
Applications of Bioluminescence Proteins 16
Infrared Thermal Imaging 16
Applications of Infrared Thermal Imaging 16
TABLE 2 ADVANTAGES AND DISADVANTAGES OF INFRARED THERMAL
IMAGING 17
ELECTRON AND ION MICROSCOPY 17
Transmission Electron Microscope (TEM) 18
Applications of Transmission Electron Microscope 18
TABLE 3 ADVANTAGES AND DISADVANTAGES OF TRANSMISSION ELECTRON
MICROSCOPES 19
Scanning Electron Microscope (SEM) 19
Applications of Scanning Electron Microscopes 19
TABLE 4 ADVANTAGES AND DISADVANTAGES OF SCANNING ELECTRON
MICROSCOPES 20
Field Ion Microscopy 20
Applications of Field Ion Microscopy 21
TABLE 5 ADVANTAGES AND DISADVANTAGES OF FIELD ION MICROSCOPY 21
SCANNING PROBE MICROSCOPY (SPM) 21
Scanning Tunneling Microscope (STM) 22
Applications of Scanning Tunneling Microscope 22
TABLE 6 ADVANTAGES AND DISADVANTAGES OF SCANNING TUNNELING
MICROSCOPES 23
Atomic Force Microscopy (AFM) 23
Modes of Operation 23
Applications of Atomic Force Microscopy 24
TABLE 7 ADVANTAGES AND DISADVANTAGES OF ATOMIC FORCE
MICROSCOPY 25
Magnetic Force Microscopy (MFM) 25
Applications of Magnetic Force Microscopy 25
TABLE 8 ADVANTAGES AND DISADVANTAGES OF MAGNETIC FORCE
MICROSCOPY 26
Near-Field Scanning Optical Microscopy (NSOM) 26
Applications of Near-Field Scanning Optical Microscopy 26
TABLE 9 ADVANTAGES AND DISADVANTAGES OF NEAR-FIELD SCANNING
OPTICAL MICROSCOPY 27
PROBES 27
MOLECULAR PROBES 28
NANOPARTICLES 28
QUANTUM DOTS 30

CHAPTER 4 REGULATORY ASPECTS 33

TABLE 10 MEMBER AGENCIES OF NATIONAL NANOTECHNOLOGY
INITIATIVE 33
NANOTECHNOLOGY PROGRAMS AT THE FDA 36
CENTER FOR BIOLOGICS EVALUATION AND RESEARCH (CBER)
PROGRAMS 36
Center for Drug Evaluation and Research (CDER) Nanotechnology
Programs 37
Center for Devices and Radiological Health (CDRH) Nanotechnology
Programs 37
Center for Food Safety and Applied Nutrition (CFSAN)
Nanotechnology Programs 37
Center for Veterinary Medicine (CVM) Nanotechnology Programs 38
National Center for Toxicological Research (NCTR) Nanotechnology
Programs 38
EPA AND NANOTECHNOLOGY 38

CHAPTER 5 NEW DEVELOPMENTS 41

NEW DEVELOPMENTS IN IMAGING SYSTEMS 41
TABLE 11 NEW DEVELOPMENTS IN OPTICAL AND THERMAL MICROSCOPY 42
TABLE 12 NEW DEVELOPMENTS IN ELECTRON AND ION MICROSCOPY 43
TABLE 13 NEW DEVELOPMENTS IN SCANNING PROBE MICROSCOPY 46
NEW DEVELOPMENTS IN THE FIELD OF PROBES 47

CHAPTER 6 GLOBAL MARKETS AND TECHNOLOGIES FOR MOLECULAR,

NANOSCALE AND ATOMIC IMAGING 51
MARKET BY TYPE 51
MARKET OVERVIEW 52
MARKET REVENUE 55
TABLE 14 GLOBAL MARKET AND TECHNOLOGIES FOR MOLECULAR,
NANOSCALE AND ATOMIC IMAGING BY TYPE, THROUGH 2017 ($ MILLIONS) 55
FIGURE 1 GLOBAL MARKET AND TECHNOLOGIES FOR MOLECULAR,
NANOSCALE AND ATOMIC IMAGING BY TYPE, 2010-2017 ($ MILLIONS) 55
MARKET SHARE 56
TABLE 15 MARKET SHARES OF GLOBAL MARKETS AND TECHNOLOGIES FOR
MOLECULAR, NANOSCALE AND ATOMIC IMAGING BY TYPE, 2011 (%) 56
FIGURE 2 MARKET SHARES OF GLOBAL MARKETS AND TECHNOLOGIES FOR
MOLECULAR, NANOSCALE AND ATOMIC IMAGING BY TYPE, 2011 (%) 56
MARKET BY REGION 57
MARKET OVERVIEW 58
MARKET REVENUE 60
TABLE 16 GLOBAL MARKETS AND TECHNOLOGIES FOR MOLECULAR,
NANOSCALE AND ATOMIC IMAGING BY REGION, THROUGH 2017 ($
MILLIONS) 60
FIGURE 3 GLOBAL MARKETS AND TECHNOLOGIES FOR MOLECULAR,
NANOSCALE AND ATOMIC IMAGING BY REGION, 2010-2017 ($ MILLIONS) 60
MARKET SHARE 61
TABLE 17 GLOBAL MARKETS AND TECHNOLOGIES FOR MOLECULAR,
NANOSCALE AND ATOMIC IMAGING BY REGION, 2011 (%) 61
FIGURE 4 GLOBAL MARKETS AND TECHNOLOGIES FOR MOLECULAR,
NANOSCALE AND ATOMIC IMAGING BY REGION, 2011 (%) 61
MARKET FOR ELECTRON AND ION MICROSCOPY BY REGION 62
MARKET OVERVIEW 62
MARKET REVENUE 63
TABLE 18 GLOBAL MARKET FOR ELECTRON AND ION MICROSCOPY BY
REGION, THROUGH 2017 ($ MILLIONS) 64
FIGURE 5 GLOBAL MARKET FOR ELECTRON AND ION MICROSCOPY BY
REGION, 2010-2017 ($ MILLIONS) 64
MARKET SHARE 64
TABLE 19 MARKET SHARE OF ELECTRON AND ION MICROSCOPY BY REGION,
2011 (%) 65
FIGURE 6 MARKET SHARE OF ELECTRON AND ION MICROSCOPY BY REGION,
2011 (%) 65
MARKET FOR IMAGING PROBES BY REGION 65
MARKET OVERVIEW 66
MARKET REVENUE 66
TABLE 20 GLOBAL MARKET FOR IMAGING PROBES BY REGION, THROUGH
2017 ($ MILLIONS) 67
FIGURE 7 GLOBAL MARKET FOR IMAGING PROBES BY REGION, 2010-2017 ($
MILLIONS) 67
MARKET SHARE 67
TABLE 21 MARKET SHARE OF IMAGING PROBES, BY REGION, 2011 (%) 68
FIGURE 8 MARKET SHARE OF IMAGING PROBES, BY REGION, 2011 (%) 68
MARKET FOR SCANNING PROBE MICROSCOPE BY REGION 68
MARKET OVERVIEW 69
MARKET REVENUE 69
TABLE 22 GLOBAL MARKET FOR SCANNING PROBE MICROSCOPY BY
REGION, THROUGH 2017 ($ MILLIONS) 70
FIGURE 9 GLOBAL MARKET FOR SCANNING PROBE MICROSCOPY BY
REGION, 2010-2017 ($ MILLIONS) 70
MARKET SHARE 70
TABLE 23 MARKET SHARE OF SCANNING PROBE MICROSCOPY BY REGION,
2011 (%) 71
FIGURE 10 MARKET SHARE OF SCANNING PROBE MICROSCOPY BY REGION,
2011 (%) 71
MARKET FOR OPTICAL AND THERMAL IMAGING BY REGION 71
MARKET OVERVIEW 72
MARKET REVENUE 72
TABLE 24 GLOBAL MARKET FOR OPTICAL AND THERMAL IMAGING BY
REGION, THROUGH 2017 ($ MILLIONS) 72
FIGURE 11 GLOBAL MARKET FOR OPTICAL AND THERMAL IMAGING BY
REGION, 2010-2017 ($ MILLIONS) 72
MARKET SHARE 73
TABLE 25 MARKET SHARE OF OPTICAL AND THERMAL IMAGING BY REGION,
2011 (%) 73
FIGURE 12 MARKET SHARE OF OPTICAL AND THERMAL IMAGING BY
REGION, 2011 (%) 73
MARKET BY APPLICATIONS 74
MARKET OVERVIEW 74
MARKET REVENUE 76
TABLE 26 GLOBAL MARKETS AND TECHNOLOGIES FOR MOLECULAR,
NANOSCALE AND ATOMIC IMAGING BY APPLICATIONS, THROUGH 2017 ($
MILLIONS) 76
FIGURE 13 GLOBAL MARKETS AND TECHNOLOGIES FOR MOLECULAR,
NANOSCALE AND ATOMIC IMAGING BY APPLICATIONS, 2010-2017 ($
MILLIONS) 76
MARKET SHARE 77
TABLE 27 MARKET SHARE OF GLOBAL MARKETS AND TECHNOLOGIES FOR
MOLECULAR, NANOSCALE AND ATOMIC IMAGING, BY APPLICATIONS, 2011
(%) 77
FIGURE 14 MARKET SHARE OF GLOBAL MARKETS AND TECHNOLOGIES FOR
MOLECULAR, NANOSCALE AND ATOMIC IMAGING BY APPLICATIONS, 2011
(%) 77

CHAPTER 7 MARKET ANALYSIS OF OPTICAL AND THERMAL MICROSCOPY 79

MARKET BY TYPE 79
MARKET OVERVIEW 79
MARKET REVENUE 81
TABLE 28 GLOBAL MARKET FOR OPTICAL AND THERMAL IMAGING BY TYPE,
THROUGH 2017 ($ MILLIONS) 82
FIGURE 15 GLOBAL MARKET FOR OPTICAL AND THERMAL IMAGING BY TYPE,
2010-2017 ($ MILLIONS) 82
MARKET SHARE 82
TABLE 29 MARKET SHARE OF IMAGING SYSTEMS BY TYPE, 2011 (%) 83
FIGURE 16 MARKET SHARE OF IMAGING SYSTEMS BY TYPE, 2011 (%) 83
MARKET BY REGION 83
MARKET OVERVIEW 83
MARKET REVENUE 84
TABLE 30 GLOBAL MARKET FOR OPTICAL AND THERMAL IMAGING BY
REGION, THROUGH 2017 ($ MILLIONS) 85
FIGURE 17 GLOBAL MARKET FOR OPTICAL AND THERMAL IMAGING BY
REGION, 2010-2017 ($ MILLIONS) 85
MARKET SHARE 85
TABLE 31 MARKET SHARE OF OPTICAL AND THERMAL IMAGING BY REGION,
2011 (%) 86
FIGURE 18 MARKET SHARE OF OPTICAL AND THERMAL IMAGING BY
REGION, 2011 (%) 86
MARKET FOR OPTICAL IMAGING BY REGION 86
MARKET OVERVIEW 86
MARKET REVENUE 87
TABLE 32 GLOBAL MARKET FOR OPTICAL IMAGING BY REGION, THROUGH
2017 ($ MILLIONS) 87
FIGURE 19 GLOBAL MARKET FOR OPTICAL IMAGING BY REGION, 2010-2017
($ MILLIONS) 88
MARKET SHARE 88
TABLE 33 MARKET SHARE OF OPTICAL IMAGING BY REGION, 2011 (%) 88
FIGURE 20 MARKET SHARE OF OPTICAL IMAGING BY REGION, 2011 (%) 88
MARKET FOR THERMAL IMAGING BY REGION 89
MARKET OVERVIEW 89
MARKET REVENUE 90
TABLE 34 GLOBAL MARKET FOR THERMAL IMAGING BY REGION, THROUGH
2017 ($ MILLIONS) 90
FIGURE 21 GLOBAL MARKET FOR THERMAL IMAGING BY REGION, 2010-2017
($ MILLIONS) 91
MARKET SHARE 91
TABLE 35 MARKET SHARE OF THERMAL IMAGING BY REGION, 2011 (%) 91
FIGURE 22 MARKET SHARE OF THERMAL IMAGING BY REGION, 2011 (%) 91
MARKET BY APPLICATIONS 92
TABLE 36 GLOBAL REVENUE FOR OPTICAL AND THERMAL IMAGING BY
APPLICATION, THROUGH 2017 ($ MILLIONS) 92
FIGURE 23 GLOBAL REVENUE FOR OPTICAL AND THERMAL IMAGING BY
APPLICATION, 2010-2017 ($ MILLIONS) 93
OPTICAL IMAGING 93
Market Revenue 94
TABLE 37 GLOBAL REVENUE FOR OPTICAL IMAGING BY APPLICATION,
THROUGH 2017 ($ MILLIONS) 94
FIGURE 24 GLOBAL REVENUE FOR OPTICAL IMAGING BY APPLICATION,
2010-2017 ($ MILLIONS) 94
THERMAL IMAGING 95
Market Revenue 96
TABLE 38 GLOBAL REVENUE FOR THERMAL IMAGING BY APPLICATION,
THROUGH 2017 ($ MILLIONS) 96
FIGURE 25 GLOBAL REVENUE FOR THERMAL IMAGING BY APPLICATION,
2010-2017 ($ MILLIONS) 96
MARKET SHARE 97
TABLE 39 MARKET SHARES OF OPTICAL AND THERMAL IMAGING BY
APPLICATION, 2011 (%) 97
FIGURE 26 MARKET SHARES OF OPTICAL AND THERMAL IMAGING BY
APPLICATION, 2011 (%) 97
INDUSTRY STRUCTURE 98
OPTICAL IMAGING (FLUORESCENCE AND BIOLUMINESCENCE
IMAGING) 98
Market Leaders 98
TABLE 40 LEADING MANUFACTURERS OF OPTICAL IMAGING 98
Market Shares 99
TABLE 41 GLOBAL MARKET SHARES OF FLUORESCENCE AND
BIOLUMINESCENCE MICROSCOPES, 2011 (%) 100
FIGURE 27 GLOBAL MARKET SHARES OF FLUORESCENCE AND
BIOLUMINESCENCE MICROSCOPES, 2011 (%) 100
THERMAL IMAGING 101
Market Leaders 101
TABLE 42 LEADING MANUFACTURERS OF THERMAL IMAGING SYSTEMS 101
Market Shares 102
TABLE 43 GLOBAL MARKET SHARES OF THERMAL IMAGING CAMERAS, 2011
(%) 103
FIGURE 28 GLOBAL MARKET SHARES OF THERMAL IMAGING CAMERAS,
2011 (%) 103

CHAPTER 8 MARKET ANALYSIS OF ELECTRON AND ION IMAGING 105

MARKET BY TYPE 105
MARKET OVERVIEW 105
MARKET REVENUE 105
TABLE 44 GLOBAL MARKET FOR ELECTRON AND ION IMAGING BY TYPE,
THROUGH 2017 ($ MILLIONS) 106
FIGURE 29 GLOBAL MARKET FOR ELECTRON AND ION IMAGING BY TYPE,
2010-2017 ($ MILLIONS) 106
MARKET SHARE 106
TABLE 45 MARKET SHARE OF IMAGING SYSTEMS BY TYPE, 2011 (%) 107
FIGURE 30 MARKET SHARE OF IMAGING SYSTEMS BY TYPE, 2011 (%) 107
MARKET BY REGION 107
MARKET OVERVIEW 108
MARKET REVENUE 108
TABLE 46 GLOBAL MARKET FOR ELECTRON AND ION MICROSCOPY BY
REGION, THROUGH 2017 ($ MILLIONS) 109
FIGURE 31 GLOBAL MARKET FOR ELECTRON AND ION MICROSCOPY BY
REGION, 2010-2017 ($ MILLIONS) 109
MARKET SHARE 110
TABLE 47 MARKET SHARE OF ELECTRON AND ION MICROSCOPY BY REGION,
2011 (%) 110
FIGURE 32 MARKET SHARE OF ELECTRON AND ION MICROSCOPY BY
REGION, 2011 (%) 110
MARKET FOR ELECTRON MICROSCOPY BY REGION 110
MARKET OVERVIEW 111
MARKET REVENUE 112
TABLE 48 GLOBAL MARKET FOR ELECTRON MICROSCOPES BY REGION,
THROUGH 2017 ($ MILLIONS) 112
FIGURE 33 GLOBAL MARKET FOR ELECTRON MICROSCOPES BY REGION,
2010-2017 ($ MILLIONS) 112
MARKET SHARE 113
TABLE 49 MARKET SHARE OF ELECTRON MICROSCOPES BY REGION, 2011
(%) 113
FIGURE 34 MARKET SHARE OF ELECTRON MICROSCOPES BY REGION, 2011
(%) 113
MARKET FOR ION MICROSCOPY BY REGION 113
MARKET OVERVIEW 114
MARKET REVENUE 115
TABLE 50 GLOBAL MARKET FOR ION MICROSCOPY BY REGION, THROUGH
2017 ($ MILLIONS) 115
FIGURE 35 GLOBAL MARKET FOR ION MICROSCOPY BY REGION, 2010-2017
($ MILLIONS) 115
MARKET SHARE 116
TABLE 51 MARKET SHARE OF ION MICROSCOPY BY REGION, 2011 (%) 116
FIGURE 36 MARKET SHARE OF ION MICROSCOPY BY REGION, 2011 (%) 116
MARKET BY APPLICATIONS 117
MARKET REVENUE 118
TABLE 52 GLOBAL REVENUE FOR ELECTRON AND ION MICROSCOPY USED
IN VARIOUS SECTORS, THROUGH 2017 ($ MILLIONS) 119
FIGURE 37 GLOBAL REVENUE FOR ELECTRON AND ION MICROSCOPY USED
IN VARIOUS SECTORS, 2010-2017 ($ MILLIONS) 119
MARKET SHARE 119
TABLE 53 ELECTRON AND ION MARKET SHARES BY APPLICATION, 2011 (%) 120
FIGURE 38 ELECTRON AND ION MARKET SHARES BY APPLICATION, 2011 (%) 120
INDUSTRY STRUCTURE 120
MARKET LEADERS 120
TABLE 54 LEADING MANUFACTURERS OF ELECTRON AND ION
MICROSCOPES 121
MARKET SHARES OF ELECTRON MICROSCOPY 122
TABLE 55 GLOBAL MARKET SHARES OF ELECTRON MICROSCOPES, 2011 (%) 122
FIGURE 39 GLOBAL MARKET SHARES OF ELECTRON MICROSCOPES, 2011 (%) 122
MARKET SHARES OF ION MICROSCOPY 123
TABLE 56 GLOBAL MARKET SHARES OF ION MICROSCOPY, 2011 (%) 123
FIGURE 40 GLOBAL MARKET SHARES OF ION MICROSCOPY, 2011 (%) 123

CHAPTER 9 MARKET ANALYSIS OF SCANNING PROBE MICROSCOPY 126

MARKET BY TYPE 126
MARKET OVERVIEW 126
MARKET REVENUE 128
TABLE 57 GLOBAL MARKET FOR SCANNING PROBE MICROSCOPY BY TYPE,
THROUGH 2017 ($ MILLIONS) 128
FIGURE 41 GLOBAL MARKET FOR SCANNING PROBE MICROSCOPY BY TYPE,
2010-2017 ($ MILLIONS) 128
MARKET SHARE 129
TABLE 58 MARKET SHARE OF SCANNING PROBE MICROSCOPY, 2011 (%) 129
FIGURE 42 MARKET SHARE OF SCANNING PROBE MICROSCOPY, 2011 (%) 129
MARKET BY REGION 129
MARKET OVERVIEW 130
MARKET REVENUE 130
TABLE 59 GLOBAL MARKET FOR SCANNING PROBE MICROSCOPY BY
REGION, THROUGH 2017 ($ MILLIONS) 131
FIGURE 43 GLOBAL MARKET FOR SCANNING PROBE MICROSCOPY BY
REGION, 2010-2017 ($ MILLIONS) 131
MARKET SHARE 132
TABLE 60 MARKET SHARE OF SCANNING PROBE MICROSCOPY BY REGION,
2011 (%) 132
FIGURE 44 MARKET SHARE OF SCANNING PROBE MICROSCOPY BY REGION,
2011 (%) 132
MARKET FOR ATOMIC FORCE MICROSCOPY BY REGION 132
MARKET OVERVIEW 133
MARKET REVENUE 133
TABLE 61 GLOBAL MARKET FOR ATOMIC FORCE MICROSCOPES BY REGION,
THROUGH 2017 ($ MILLIONS) 134
FIGURE 45 GLOBAL MARKET FOR ATOMIC FORCE MICROSCOPES BY REGION,
2010-2017 ($ MILLIONS) 134
MARKET SHARE 134
TABLE 62 MARKET SHARE OF ATOMIC FORCE MICROSCOPES BY REGION,
2011 (%) 135
FIGURE 46 MARKET SHARE OF ATOMIC FORCE MICROSCOPES BY REGION,
2011 (%) 135
MARKET FOR OTHER SCANNING PROBE MICROSCOPES BY REGION 135
MARKET OVERVIEW 136
MARKET REVENUE 136
TABLE 63 GLOBAL MARKET FOR OTHER SCANNING PROBE MICROSCOPES
BY REGION, THROUGH 2017 ($ MILLIONS) 136
FIGURE 47 GLOBAL MARKET FOR OTHER SCANNING PROBE MICROSCOPES
BY REGION, 2010-2017 ($ MILLIONS) 137
MARKET SHARE 137
TABLE 64 MARKET SHARE OF OTHER SCANNING PROBE MICROSCOPES BY
REGION, 2011 (%) 138
FIGURE 48 MARKET SHARE OF OTHER SCANNING PROBE MICROSCOPES BY
REGION, 2011 (%) 138
MARKET BY APPLICATIONS 138
TABLE 65 GLOBAL REVENUE FOR SCANNING PROBE MICROSCOPY BY
APPLICATIONS, THROUGH 2017 ($ MILLIONS) 139
FIGURE 49 GLOBAL REVENUE FOR SCANNING PROBE MICROSCOPY BY
APPLICATIONS, 2010-2017 ($ MILLIONS) 139
ATOMIC FORCE MICROSCOPY 140
Market Revenue 141
TABLE 66 GLOBAL REVENUE FOR ATOMIC FORCE MICROSCOPES BY
APPLICATIONS, THROUGH 2017 ($ MILLIONS) 141
FIGURE 50 GLOBAL REVENUE FOR ATOMIC FORCE MICROSCOPES BY
APPLICATIONS, 2010-2017 ($ MILLIONS) 141
OTHER SCANNING PROBE MICROSCOPES 142
Market Revenue 142
TABLE 67 GLOBAL REVENUE FOR OTHER SCANNING PROBE MICROSCOPES
BY APPLICATIONS, THROUGH 2017 ($ MILLIONS) 143
FIGURE 51 GLOBAL REVENUE FOR OTHER SCANNING PROBE MICROSCOPES
BY APPLICATIONS, 2010-2017 ($ MILLIONS) 143
Market Share 144
TABLE 68 MARKET SHARE OF SCANNING PROBE MICROSCOPY BY
APPLICATION, 2011 (%) 144
FIGURE 52 MARKET SHARE OF SCANNING PROBE MICROSCOPY BY
APPLICATION, 2011 (%) 144
INDUSTRY STRUCTURE 144
MARKET LEADERS 144
TABLE 69 LEADING MANUFACTURERS OF SCANNING PROBE MICROSCOPES 144
MARKET SHARES 146
Atomic Force Microscopes 146
TABLE 70 GLOBAL MARKET SHARES OF ATOMIC FORCE MICROSCOPES,
2011 (%) 147
FIGURE 53 GLOBAL MARKET SHARES OF ATOMIC FORCE MICROSCOPES,
2011 (%) 147
Other Scanning Probe Microscopes 147
TABLE 71 GLOBAL MARKET SHARES OF OTHER SCANNING PROBE
MICROSCOPES, 2011 (%) 148
FIGURE 54 GLOBAL MARKET SHARES OF OTHER SCANNING PROBE
MICROSCOPES, 2011 (%) 148

CHAPTER 10 IMAGING PROBES 150

MARKET BY TYPE 150
MARKET OVERVIEW 150
MARKET REVENUE 151
TABLE 72 GLOBAL MARKET FOR IMAGING PROBES BY TYPE, THROUGH 2017
($ MILLIONS) 152
FIGURE 55 GLOBAL MARKET FOR IMAGING PROBES BY TYPE, 2010-2017 ($
MILLIONS) 152
MARKET SHARE 153
TABLE 73 MARKET SHARE OF IMAGING PROBES, 2011 (%) 153
FIGURE 56 MARKET SHARE OF IMAGING PROBES, 2011 (%) 153
MARKET BY REGION 153
MARKET OVERVIEW 154
MARKET REVENUE 154
TABLE 74 GLOBAL MARKET FOR IMAGING PROBES BY REGION, THROUGH
2017 ($ MILLIONS) 155
FIGURE 57 GLOBAL MARKET FOR IMAGING PROBES BY REGION, 2010-2017
($ MILLIONS) 155
MARKET SHARE 155
TABLE 75 MARKET SHARE OF IMAGING PROBES BY REGION, 2011 (%) 156
FIGURE 58 MARKET SHARE OF IMAGING PROBES BY REGION, 2011 (%) 156
MARKET FOR FLUORESCENT AND BIOLUMINESCENT PROBES BY
REGION 156
MARKET OVERVIEW 157
MARKET REVENUE 157
TABLE 76 GLOBAL MARKET FOR FLUORESCENT AND BIOLUMINESCENT
PROBES BY REGION, THROUGH 2017 ($ MILLIONS) 158
FIGURE 59 GLOBAL MARKET FOR FLUORESCENT AND BIOLUMINESCENT
PROBES BY REGION, 2010-2017 ($ MILLIONS) 158
MARKET SHARE 158
TABLE 77 MARKET SHARE OF FLUORESCENT AND BIOLUMINESCENT
PROBES BY REGION, 2011 (%) 159
FIGURE 60 MARKET SHARE OF FLUORESCENT AND BIOLUMINESCENT
PROBES BY REGION, 2011 (%) 159
MARKET FOR NANOPARTICLES AND QUANTUM DOTS BY REGION 159
MARKET OVERVIEW 160
MARKET REVENUE 160
TABLE 78 GLOBAL MARKET FOR NANOPARTICLES AND QUANTUM DOTS BY
REGION, THROUGH 2017 ($ MILLIONS) 161
FIGURE 61 GLOBAL MARKET FOR NANOPARTICLES AND QUANTUM DOTS BY
REGION, 2010-2017 ($ MILLIONS) 161
MARKET SHARE 161
TABLE 79 MARKET SHARE OF NANOPARTICLES AND QUANTUM DOTS BY
REGION, 2011 (%) 162
FIGURE 62 MARKET SHARE OF NANOPARTICLES AND QUANTUM DOTS BY
REGION, 2011 (%) 162
MARKET BY APPLICATIONS 162
TABLE 80 GLOBAL REVENUE FOR IMAGING PROBES USED IN VARIOUS
SECTORS, THROUGH 2017 ($ MILLIONS) 163
FIGURE 63 GLOBAL REVENUE FOR IMAGING PROBES USED IN VARIOUS
SECTORS, 2010-2017 ($ MILLIONS) 163
FLUORESCENT AND BIOLUMINESCENT PROBES 164
Market Revenue 164
TABLE 81 GLOBAL REVENUE FOR FLUORESCENT AND BIOLUMINESCENT
PROBES USED IN VARIOUS SECTORS, THROUGH 2017 ($ MILLIONS) 165
FIGURE 64 GLOBAL REVENUE FOR FLUORESCENT AND BIOLUMINESCENT
PROBES USED IN VARIOUS SECTORS, 2010-2017 ($ MILLIONS) 165
NANOPARTICLES AND QUANTUM DOTS BY APPLICATION 166
Market Revenue 166
TABLE 82 GLOBAL REVENUE FOR NANOPARTICLES AND QUANTUM DOTS
USED IN VARIOUS SECTORS, THROUGH 2017 ($ MILLIONS) 167
FIGURE 65 GLOBAL REVENUE FOR NANOPARTICLES AND QUANTUM DOTS
USED IN VARIOUS SECTORS, 2010-2017 ($ MILLIONS) 167
MARKET SHARE 168
TABLE 83 IMAGING PROBES MARKET SHARES BY APPLICATION, 2011 (%) 168
FIGURE 66 IMAGING PROBES MARKET SHARES BY APPLICATION, 2011 (%) 168
INDUSTRY STRUCTURE 169
FLUORESCENT AND BIOLUMINESCENCE IMAGING PROBES 169
Market Leaders 169
TABLE 84 LEADING MANUFACTURERS OF FLUORESCENCE AND
BIOLUMINESCENCE IMAGING PROBES 169
Market Shares 171
TABLE 85 GLOBAL MARKET SHARES OF FLUORESCENCE AND
BIOLUMINESCENCE IMAGING PROBES, 2011 (%) 172
FIGURE 67 GLOBAL MARKET SHARES OF FLUORESCENCE AND
BIOLUMINESCENCE IMAGING PROBES, 2011 (%) 172
NANOPARTICLES AND QUANTUM DOTS 173
Market Leaders 173
TABLE 86 LEADING MANUFACTURERS OF QUANTUM DOTS 173
Market Shares 175
TABLE 87 GLOBAL MARKET SHARES OF NANOPARTICLES AND QUANTUM
DOTS, 2011 (%) 175
FIGURE 68 GLOBAL MARKET SHARES OF NANOPARTICLES AND QUANTUM
DOTS, 2011 (%) 175

CHAPTER 11 PATENT ANALYSIS 177

PATENT ANALYSIS OF IMAGING SYSTEMS 178
PATENTS BY YEAR 178
TABLE 88 NUMBER OF PATENTS BY YEAR, 2008-2012 (NUMBER/%) 178
FIGURE 69 NUMBER OF PATENTS, BY YEAR, 2008-2012 178
FIGURE 70 NUMBER OF PATENTS, BY YEAR, 2008-2012 (%) 178
PATENTS BY TYPE 179
TABLE 89 NUMBER OF PATENTS BY TYPE, 2008-2012 179
FIGURE 71 NUMBER OF PATENTS BY TYPE, 2008-2012 (NUMBER) 179
PATENTS BY COUNTRY 180
TABLE 90 NUMBER OF PATENTS BY COUNTRY, 2008-2012 181
FIGURE 72 NUMBER OF PATENTS BY COUNTRY, 2008-2012 181
PATENTS BY COMPANY 182
TABLE 91 NUMBER OF PATENTS BY COMPANY, 2008-2012 182
PATENTS BY ASSIGNEE 183
TABLE 92 NUMBER OF PATENTS BY ASSIGNEE, 2008-2012 184
FIGURE 73 NUMBER OF PATENTS BY ASSIGNEE, 2008-2012 184
PATENT ANALYSIS OF IMAGING PROBES 184
PATENTS BY YEAR 184
TABLE 93 NUMBER OF PATENTS BY YEAR, 2008-2012 185
FIGURE 74 NUMBER OF PATENTS BY YEAR, 2008-2012 185
FIGURE 75 NUMBER OF PATENTS BY YEAR, 2008-2012 (%) 185
PATENTS BY TYPE 186
TABLE 94 NUMBER OF PATENTS BY TYPE, 2008-2012 186
FIGURE 76 NUMBER OF PATENTS BY TYPE, 2008-2012 186
PATENTS BY COUNTRY 186
TABLE 95 NUMBER OF PATENTS BY COUNTRY, 2008-2012 187
PATENTS BY COMPANY 187
TABLE 96 NUMBER OF PATENTS BY COMPANY, 2008-2012 188
PATENTS BY ASSIGNEE 188
TABLE 97 NUMBER OF PATENTS BY ASSIGNEE, 2008-2012 188

CHAPTER 12 CURRENT SITUATION 190

TRENDS IN MOLECULAR, ATOMIC AND NANOSCALE IMAGING 190
CONSIDERABLE GROWTH IN ELECTRON AND SCANNING PROBE
MICROSCOPES 190
ASIA PACIFIC REGIONS: KEY REGIONS OF GROWTH 191
FACTORS AFFECTING THE MARKET 191
PRODUCT INNOVATIONS 191
DEVELOPMENT OF HYBRID SYSTEMS 191
MINIATURIZATION OF ELECTRONIC DEVICES 192
NEED OF QUALITY CONTROL IN ELECTRONICS 192
BABY-BOOMER GENERATION 192
INCREASING INCIDENCE OF LIFE-THREATENING DISEASES 192
IMPROVING ECONOMIC CONDITIONS OF EMERGING COUNTRIES 193
GOVERNMENT SUPPORT 193

CHAPTER 13 COMPANY PROFILES 195

AFFYMETRIX 195
AGILENT TECHNOLOGIES INC. 195
ANASPEC INC. 196
A.P.E. RESEARCH 197
APPLIED NANOTECH HOLDINGS INC. 197
AXIS COMMUNICATIONS AB 198
BECTON DICKINSON COMPANY 198
BIOSEARCH TECHNOLOGIES INC. 199
BRUKER CORPORATION 199
CARL ZEISS MICROSCOPY GMBH 200
CLONTECH LABORATORIES 201
DANAHAR CORPORATION 202
FEI COMPANY 203
FLIR SYSTEMS INC. 203
FLUKE CORPORATION 204
HAMAMATSU CORPORATION 205
HITACHI HIGH-TECHNOLOGIES 205
JEOL LTD. 206
LAMBERT INSTRUMENTS 207
LIFE TECHNOLOGIES 207
NANOCO GROUP PLC 208
NANOPHASE TECHNOLOGIES CORPORATION 208
NIKON CORPORATION 209
NT-MDT COMPANY 209
OLYMPUS CORPORATION 210
OXFORD INSTRUMENTS 210
PERKIN ELMER 211
PROMEGA 212
RHK TECHNOLOGY INC. 212
SIGMA-ALDRICH 212
THERMO FISHER SCIENTIFIC 213
WITEC FOCUS INNOVATIONS 214
XENICS INFRARED SOLUTIONS 214

CHAPTER 14 APPENDIX: ABBREVIATIONS 217



LIST OF TABLES

SUMMARY TABLE GLOBAL REVENUE OF MOLECULAR, ATOMIC AND
NANOSCALE IMAGING, THROUGH 2017 ($ MILLIONS) 8
TABLE 1 HISTORY AND DEVELOPMENT OF IMAGING TECHNIQUES 12
TABLE 2 ADVANTAGES AND DISADVANTAGES OF INFRARED THERMAL
IMAGING 17
TABLE 3 ADVANTAGES AND DISADVANTAGES OF TRANSMISSION ELECTRON
MICROSCOPES 19
TABLE 4 ADVANTAGES AND DISADVANTAGES OF SCANNING ELECTRON
MICROSCOPES 20
TABLE 5 ADVANTAGES AND DISADVANTAGES OF FIELD ION MICROSCOPY 21
TABLE 6 ADVANTAGES AND DISADVANTAGES OF SCANNING TUNNELING
MICROSCOPES 23
TABLE 7 ADVANTAGES AND DISADVANTAGES OF ATOMIC FORCE
MICROSCOPY 25
TABLE 8 ADVANTAGES AND DISADVANTAGES OF MAGNETIC FORCE
MICROSCOPY 26
TABLE 9 ADVANTAGES AND DISADVANTAGES OF NEAR-FIELD SCANNING
OPTICAL MICROSCOPY 27
TABLE 10 MEMBER AGENCIES OF NATIONAL NANOTECHNOLOGY INITIATIVE 33
TABLE 11 NEW DEVELOPMENTS IN OPTICAL AND THERMAL MICROSCOPY 42
TABLE 12 NEW DEVELOPMENTS IN ELECTRON AND ION MICROSCOPY 43
TABLE 13 NEW DEVELOPMENTS IN SCANNING PROBE MICROSCOPY 46
TABLE 14 GLOBAL MARKET AND TECHNOLOGIES FOR MOLECULAR,
NANOSCALE AND ATOMIC IMAGING BY TYPE, THROUGH 2017 ($ MILLIONS) 55
TABLE 15 MARKET SHARES OF GLOBAL MARKETS AND TECHNOLOGIES FOR
MOLECULAR, NANOSCALE AND ATOMIC IMAGING BY TYPE, 2011 (%) 56
TABLE 16 GLOBAL MARKETS AND TECHNOLOGIES FOR MOLECULAR,
NANOSCALE AND ATOMIC IMAGING BY REGION, THROUGH 2017 ($ MILLIONS) 60
TABLE 17 GLOBAL MARKETS AND TECHNOLOGIES FOR MOLECULAR,
NANOSCALE AND ATOMIC IMAGING BY REGION, 2011 (%) 61
TABLE 18 GLOBAL MARKET FOR ELECTRON AND ION MICROSCOPY BY
REGION, THROUGH 2017 ($ MILLIONS) 64
TABLE 19 MARKET SHARE OF ELECTRON AND ION MICROSCOPY BY REGION,
2011 (%) 65
TABLE 20 GLOBAL MARKET FOR IMAGING PROBES BY REGION, THROUGH
2017 ($ MILLIONS) 67
TABLE 21 MARKET SHARE OF IMAGING PROBES, BY REGION, 2011 (%) 68
TABLE 22 GLOBAL MARKET FOR SCANNING PROBE MICROSCOPY BY REGION,
THROUGH 2017 ($ MILLIONS) 70
TABLE 23 MARKET SHARE OF SCANNING PROBE MICROSCOPY BY REGION,
2011 (%) 71
TABLE 24 GLOBAL MARKET FOR OPTICAL AND THERMAL IMAGING BY
REGION, THROUGH 2017 ($ MILLIONS) 72
TABLE 25 MARKET SHARE OF OPTICAL AND THERMAL IMAGING BY REGION,
2011 (%) 73
TABLE 26 GLOBAL MARKETS AND TECHNOLOGIES FOR MOLECULAR,
NANOSCALE AND ATOMIC IMAGING BY APPLICATIONS, THROUGH 2017 ($
MILLIONS) 76
TABLE 27 MARKET SHARE OF GLOBAL MARKETS AND TECHNOLOGIES FOR
MOLECULAR, NANOSCALE AND ATOMIC IMAGING, BY APPLICATIONS, 2011
(%) 77
TABLE 28 GLOBAL MARKET FOR OPTICAL AND THERMAL IMAGING BY TYPE,
THROUGH 2017 ($ MILLIONS) 82
TABLE 29 MARKET SHARE OF IMAGING SYSTEMS BY TYPE, 2011 (%) 83
TABLE 30 GLOBAL MARKET FOR OPTICAL AND THERMAL IMAGING BY
REGION, THROUGH 2017 ($ MILLIONS) 85
TABLE 31 MARKET SHARE OF OPTICAL AND THERMAL IMAGING BY REGION,
2011 (%) 86
TABLE 32 GLOBAL MARKET FOR OPTICAL IMAGING BY REGION, THROUGH
2017 ($ MILLIONS) 87
TABLE 33 MARKET SHARE OF OPTICAL IMAGING BY REGION, 2011 (%) 88
TABLE 34 GLOBAL MARKET FOR THERMAL IMAGING BY REGION, THROUGH
2017 ($ MILLIONS) 90
TABLE 35 MARKET SHARE OF THERMAL IMAGING BY REGION, 2011 (%) 91
TABLE 36 GLOBAL REVENUE FOR OPTICAL AND THERMAL IMAGING BY
APPLICATION, THROUGH 2017 ($ MILLIONS) 92
TABLE 37 GLOBAL REVENUE FOR OPTICAL IMAGING BY APPLICATION,
THROUGH 2017 ($ MILLIONS) 94
TABLE 38 GLOBAL REVENUE FOR THERMAL IMAGING BY APPLICATION,
THROUGH 2017 ($ MILLIONS) 96
TABLE 39 MARKET SHARES OF OPTICAL AND THERMAL IMAGING BY
APPLICATION, 2011 (%) 97
TABLE 40 LEADING MANUFACTURERS OF OPTICAL IMAGING 98
TABLE 41 GLOBAL MARKET SHARES OF FLUORESCENCE AND
BIOLUMINESCENCE MICROSCOPES, 2011 (%) 100
TABLE 42 LEADING MANUFACTURERS OF THERMAL IMAGING SYSTEMS 101
TABLE 43 GLOBAL MARKET SHARES OF THERMAL IMAGING CAMERAS, 2011
(%) 103
TABLE 44 GLOBAL MARKET FOR ELECTRON AND ION IMAGING BY TYPE,
THROUGH 2017 ($ MILLIONS) 106
TABLE 45 MARKET SHARE OF IMAGING SYSTEMS BY TYPE, 2011 (%) 107
TABLE 46 GLOBAL MARKET FOR ELECTRON AND ION MICROSCOPY BY
REGION, THROUGH 2017 ($ MILLIONS) 109
TABLE 47 MARKET SHARE OF ELECTRON AND ION MICROSCOPY BY REGION,
2011 (%) 110
TABLE 48 GLOBAL MARKET FOR ELECTRON MICROSCOPES BY REGION,
THROUGH 2017 ($ MILLIONS) 112
TABLE 49 MARKET SHARE OF ELECTRON MICROSCOPES BY REGION, 2011 (%) 113
TABLE 50 GLOBAL MARKET FOR ION MICROSCOPY BY REGION, THROUGH
2017 ($ MILLIONS) 115
TABLE 51 MARKET SHARE OF ION MICROSCOPY BY REGION, 2011 (%) 116
TABLE 52 GLOBAL REVENUE FOR ELECTRON AND ION MICROSCOPY USED IN
VARIOUS SECTORS, THROUGH 2017 ($ MILLIONS) 119
TABLE 53 ELECTRON AND ION MARKET SHARES BY APPLICATION, 2011 (%) 120
TABLE 54 LEADING MANUFACTURERS OF ELECTRON AND ION
MICROSCOPES 121
TABLE 55 GLOBAL MARKET SHARES OF ELECTRON MICROSCOPES, 2011 (%) 122
TABLE 56 GLOBAL MARKET SHARES OF ION MICROSCOPY, 2011 (%) 123
TABLE 57 GLOBAL MARKET FOR SCANNING PROBE MICROSCOPY BY TYPE,
THROUGH 2017 ($ MILLIONS) 128
TABLE 58 MARKET SHARE OF SCANNING PROBE MICROSCOPY, 2011 (%) 129
TABLE 59 GLOBAL MARKET FOR SCANNING PROBE MICROSCOPY BY REGION,
THROUGH 2017 ($ MILLIONS) 131
TABLE 60 MARKET SHARE OF SCANNING PROBE MICROSCOPY BY REGION,
2011 (%) 132
TABLE 61 GLOBAL MARKET FOR ATOMIC FORCE MICROSCOPES BY REGION,
THROUGH 2017 ($ MILLIONS) 134
TABLE 62 MARKET SHARE OF ATOMIC FORCE MICROSCOPES BY REGION,
2011 (%) 135
TABLE 63 GLOBAL MARKET FOR OTHER SCANNING PROBE MICROSCOPES BY
REGION, THROUGH 2017 ($ MILLIONS) 136
TABLE 64 MARKET SHARE OF OTHER SCANNING PROBE MICROSCOPES BY
REGION, 2011 (%) 138
TABLE 65 GLOBAL REVENUE FOR SCANNING PROBE MICROSCOPY BY
APPLICATIONS, THROUGH 2017 ($ MILLIONS) 139
TABLE 66 GLOBAL REVENUE FOR ATOMIC FORCE MICROSCOPES BY
APPLICATIONS, THROUGH 2017 ($ MILLIONS) 141
TABLE 67 GLOBAL REVENUE FOR OTHER SCANNING PROBE MICROSCOPES
BY APPLICATIONS, THROUGH 2017 ($ MILLIONS) 143
TABLE 68 MARKET SHARE OF SCANNING PROBE MICROSCOPY BY
APPLICATION, 2011 (%) 144
TABLE 69 LEADING MANUFACTURERS OF SCANNING PROBE MICROSCOPES 144
TABLE 70 GLOBAL MARKET SHARES OF ATOMIC FORCE MICROSCOPES, 2011
(%) 147
TABLE 71 GLOBAL MARKET SHARES OF OTHER SCANNING PROBE
MICROSCOPES, 2011 (%) 148
TABLE 72 GLOBAL MARKET FOR IMAGING PROBES BY TYPE, THROUGH 2017
($ MILLIONS) 152
TABLE 73 MARKET SHARE OF IMAGING PROBES, 2011 (%) 153
TABLE 74 GLOBAL MARKET FOR IMAGING PROBES BY REGION, THROUGH
2017 ($ MILLIONS) 155
TABLE 75 MARKET SHARE OF IMAGING PROBES BY REGION, 2011 (%) 156
TABLE 76 GLOBAL MARKET FOR FLUORESCENT AND BIOLUMINESCENT
PROBES BY REGION, THROUGH 2017 ($ MILLIONS) 158
TABLE 77 MARKET SHARE OF FLUORESCENT AND BIOLUMINESCENT PROBES
BY REGION, 2011 (%) 159
TABLE 78 GLOBAL MARKET FOR NANOPARTICLES AND QUANTUM DOTS BY
REGION, THROUGH 2017 ($ MILLIONS) 161
TABLE 79 MARKET SHARE OF NANOPARTICLES AND QUANTUM DOTS BY
REGION, 2011 (%) 162
TABLE 80 GLOBAL REVENUE FOR IMAGING PROBES USED IN VARIOUS
SECTORS, THROUGH 2017 ($ MILLIONS) 163
TABLE 81 GLOBAL REVENUE FOR FLUORESCENT AND BIOLUMINESCENT
PROBES USED IN VARIOUS SECTORS, THROUGH 2017 ($ MILLIONS) 165
TABLE 82 GLOBAL REVENUE FOR NANOPARTICLES AND QUANTUM DOTS
USED IN VARIOUS SECTORS, THROUGH 2017 ($ MILLIONS) 167
TABLE 83 IMAGING PROBES MARKET SHARES BY APPLICATION, 2011 (%) 168
TABLE 84 LEADING MANUFACTURERS OF FLUORESCENCE AND
BIOLUMINESCENCE IMAGING PROBES 169
TABLE 85 GLOBAL MARKET SHARES OF FLUORESCENCE AND
BIOLUMINESCENCE IMAGING PROBES, 2011 (%) 172
TABLE 86 LEADING MANUFACTURERS OF QUANTUM DOTS 173
TABLE 87 GLOBAL MARKET SHARES OF NANOPARTICLES AND QUANTUM
DOTS, 2011 (%) 175
TABLE 88 NUMBER OF PATENTS BY YEAR, 2008-2012 (NUMBER/%) 178
TABLE 89 NUMBER OF PATENTS BY TYPE, 2008-2012 179
TABLE 90 NUMBER OF PATENTS BY COUNTRY, 2008-2012 181
TABLE 91 NUMBER OF PATENTS BY COMPANY, 2008-2012 182
TABLE 92 NUMBER OF PATENTS BY ASSIGNEE, 2008-2012 184
TABLE 93 NUMBER OF PATENTS BY YEAR, 2008-2012 185
TABLE 94 NUMBER OF PATENTS BY TYPE, 2008-2012 186
TABLE 95 NUMBER OF PATENTS BY COUNTRY, 2008-2012 187
TABLE 96 NUMBER OF PATENTS BY COMPANY, 2008-2012 188
TABLE 97 NUMBER OF PATENTS BY ASSIGNEE, 2008-2012 188



LIST OF FIGURES

SUMMARY FIGURE GLOBAL REVENUE OF MOLECULAR, ATOMIC AND
NANOSCALE IMAGING, 2010-2017 ($ MILLIONS) 8
FIGURE 1 GLOBAL MARKET AND TECHNOLOGIES FOR MOLECULAR,
NANOSCALE AND ATOMIC IMAGING BY TYPE, 2010-2017 ($ MILLIONS) 55
FIGURE 2 MARKET SHARES OF GLOBAL MARKETS AND TECHNOLOGIES FOR
MOLECULAR, NANOSCALE AND ATOMIC IMAGING BY TYPE, 2011 (%) 56
FIGURE 3 GLOBAL MARKETS AND TECHNOLOGIES FOR MOLECULAR,
NANOSCALE AND ATOMIC IMAGING BY REGION, 2010-2017 ($ MILLIONS) 60
FIGURE 4 GLOBAL MARKETS AND TECHNOLOGIES FOR MOLECULAR,
NANOSCALE AND ATOMIC IMAGING BY REGION, 2011 (%) 61
FIGURE 5 GLOBAL MARKET FOR ELECTRON AND ION MICROSCOPY BY
REGION, 2010-2017 ($ MILLIONS) 64
FIGURE 6 MARKET SHARE OF ELECTRON AND ION MICROSCOPY BY REGION,
2011 (%) 65
FIGURE 7 GLOBAL MARKET FOR IMAGING PROBES BY REGION, 2010-2017 ($
MILLIONS) 67
FIGURE 8 MARKET SHARE OF IMAGING PROBES, BY

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