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Mycobacterium Tuberculosis Infections - Pipeline Review, H1 2014

  • March 2014
  • -
  • Global Markets Direct
  • -
  • 70 pages

Mycobacterium Tuberculosis Infections - Pipeline Review, H1 2014

Summary

Global Markets Direct’s, ‘Mycobacterium Tuberculosis Infections - Pipeline Review, H1 2014’, provides an overview of the Mycobacterium Tuberculosis Infections’s therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Mycobacterium Tuberculosis Infections, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Mycobacterium Tuberculosis Infections and special features on late-stage and discontinued projects.

Global Markets Direct’s report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct’s proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct’s team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope

- The report provides a snapshot of the global therapeutic landscape of Mycobacterium Tuberculosis Infections
- The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities
- The report reviews key players involved in the therapeutics development for Mycobacterium Tuberculosis Infections and enlists all their major and minor projects
- The report summarizes all the dormant and discontinued pipeline projects
- A review of the Mycobacterium Tuberculosis Infections products under development by companies and universities/research institutes based on information derived from company and industry-specific sources
- Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages
- A detailed assessment of monotherapy and combination therapy pipeline projects
- Coverage of the Mycobacterium Tuberculosis Infections pipeline on the basis of target, MoA, route of administration and molecule type
- Latest news and deals relating related to pipeline products

Reasons to buy

- Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies
- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
- Develop strategic initiatives by understanding the focus areas of leading companies
- Identify and understand important and diverse types of therapeutics under development for Mycobacterium Tuberculosis Infections
- Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline
- Devise corrective measures for pipeline projects by understanding Mycobacterium Tuberculosis Infections pipeline depth and focus of Indication therapeutics
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
- Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline

Table Of Contents

Mycobacterium Tuberculosis Infections - Pipeline Review, H1 2014
Table of Contents
Table of Contents 2
List of Tables 5
List of Figures 6
Introduction 7
Global Markets Direct Report Coverage 7
Mycobacterium Tuberculosis Infections Overview 8
Therapeutics Development 9
Pipeline Products for Mycobacterium Tuberculosis Infections - Overview 9
Pipeline Products for Mycobacterium Tuberculosis Infections - Comparative Analysis 10
Mycobacterium Tuberculosis Infections - Therapeutics under Development by Companies 11
Mycobacterium Tuberculosis Infections - Therapeutics under Investigation by Universities/Institutes 13
Mycobacterium Tuberculosis Infections - Pipeline Products Glance 15
Clinical Stage Products 15
Early Stage Products 16
Mycobacterium Tuberculosis Infections - Products under Development by Companies 17
Mycobacterium Tuberculosis Infections - Products under Investigation by Universities/Institutes 18
Mycobacterium Tuberculosis Infections - Companies Involved in Therapeutics Development 19
AstraZeneca PLC 19
GlaxoSmithKline plc 20
Novartis AG 21
Oragenics, Inc. 22
Debiopharm International S.A. 23
Archivel Farma S.L. 24
Sphaera Pharma Pvt. Ltd. 25
Bioversys AG 26
Mycobacterium Tuberculosis Infections - Therapeutics Assessment 27
Assessment by Monotherapy Products 27
Assessment by Combination Products 28
Assessment by Target 29
Assessment by Mechanism of Action 31
Assessment by Route of Administration 33
Assessment by Molecule Type 35
Drug Profiles 37
RUTI Vaccine - Drug Profile 37
Product Description 37
Mechanism of Action 37
RandD Progress 37
MU-1140 - Drug Profile 38
Product Description 38
Mechanism of Action 38
RandD Progress 38
MU-1140-S - Drug Profile 40
Product Description 40
Mechanism of Action 40
RandD Progress 40
(BV-6481 + ethionamide) - Drug Profile 42
Product Description 42
Mechanism of Action 42
RandD Progress 42
Biotin Triazoles - Drug Profile 43
Product Description 43
Mechanism of Action 43
RandD Progress 43
Mycobacterial Gyrase Inhibitor Program - Drug Profile 44
Product Description 44
Mechanism of Action 44
RandD Progress 44
rAMtb-SIVgag Vaccine - Drug Profile 45
Product Description 45
Mechanism of Action 45
RandD Progress 45
HT-04 - Drug Profile 46
Product Description 46
Mechanism of Action 46
RandD Progress 46
NITD-349 - Drug Profile 47
Product Description 47
Mechanism of Action 47
RandD Progress 47
Small Molecules to Inhibit Structural Protein FtsZ for Bacterial Infections - Drug Profile 48
Product Description 48
Mechanism of Action 48
RandD Progress 48
Small Molecules for Bacterial and Viral Infections - Drug Profile 50
Product Description 50
Mechanism of Action 50
RandD Progress 50
Fabl Inhibitor Program - Drug Profile 51
Product Description 51
Mechanism of Action 51
RandD Progress 51
Aminopyrazinamides - Drug Profile 52
Product Description 52
Mechanism of Action 52
RandD Progress 52
MDR And XDR Tuberculosis Program - Drug Profile 53
Product Description 53
Mechanism of Action 53
RandD Progress 53
Small Molecules for Bacterial Infections - Drug Profile 54
Product Description 54
Mechanism of Action 54
RandD Progress 54
KKL-35 - Drug Profile 55
Product Description 55
Mechanism of Action 55
RandD Progress 55
R-12 - Drug Profile 56
Product Description 56
Mechanism of Action 56
RandD Progress 56
R-13 - Drug Profile 57
Product Description 57
Mechanism of Action 57
RandD Progress 57
Compound-87 - Drug Profile 58
Product Description 58
Mechanism of Action 58
RandD Progress 58
NC-00094221 - Drug Profile 59
Product Description 59
Mechanism of Action 59
RandD Progress 59
Cephalosporins - Drug Profile 60
Product Description 60
Mechanism of Action 60
RandD Progress 60
Mycobacterium Tuberculosis Infections - Recent Pipeline Updates 61
Mycobacterium Tuberculosis Infections - Dormant Projects 63
Mycobacterium Tuberculosis Infections - Product Development Milestones 64
Featured News and Press Releases 64
Dec 20, 2013: SIRTURO Receives Positive Opinion from the Committee for MedicinalProducts for Human Use as Part of Combination Therapy to Treat Adults with Pulmonary Multi-Drug Resistant Tuberculosis 64
Aug 01, 2013: Aradigm Awarded NIH Grant to Investigate the Treatment of Pulmonary Non-Tuberculous Mycobacterial Infections with Pulmaquin and Lipoquin 64
Jun 17, 2013: Researchers Identify New Compound Effective Against Persistent And Drug-Resistant Tuberculosis 65
Feb 12, 2013: Oragenics-Intrexon Collaboration Announces Significant Progress Towards Commercial Production of Lead Lantibiotic MU1140 67
Dec 01, 2011: Vaccine Targeting Latent Tuberculosis Enters Clinical Testing 68
Appendix 69
Methodology 69
Coverage 69
Secondary Research 69
Primary Research 69
Expert Panel Validation 69
Contact Us 70
Disclaimer 70

List of Tables

Number of Products under Development for Mycobacterium Tuberculosis Infections, H1 2014 9
Number of Products under Development for Mycobacterium Tuberculosis Infections - Comparative Analysis, H1 2014 10
Number of Products under Development by Companies, H1 2014 12
Number of Products under Investigation by Universities/Institutes, H1 2014 14
Comparative Analysis by Clinical Stage Development, H1 2014 15
Comparative Analysis by Early Stage Development, H1 2014 16
Products under Development by Companies, H1 2014 17
Products under Investigation by Universities/Institutes, H1 2014 18
Mycobacterium Tuberculosis Infections - Pipeline by AstraZeneca PLC, H1 2014 19
Mycobacterium Tuberculosis Infections - Pipeline by GlaxoSmithKline plc, H1 2014 20
Mycobacterium Tuberculosis Infections - Pipeline by Novartis AG, H1 2014 21
Mycobacterium Tuberculosis Infections - Pipeline by Oragenics, Inc., H1 2014 22
Mycobacterium Tuberculosis Infections - Pipeline by Debiopharm International S.A., H1 2014 23
Mycobacterium Tuberculosis Infections - Pipeline by Archivel Farma S.L., H1 2014 24
Mycobacterium Tuberculosis Infections - Pipeline by Sphaera Pharma Pvt. Ltd., H1 2014 25
Mycobacterium Tuberculosis Infections - Pipeline by Bioversys AG, H1 2014 26
Assessment by Monotherapy Products, H1 2014 27
Assessment by Combination Products, H1 2014 28
Number of Products by Stage and Target, H1 2014 30
Number of Products by Stage and Mechanism of Action, H1 2014 32
Number of Products by Stage and Route of Administration, H1 2014 34
Number of Products by Stage and Molecule Type, H1 2014 36
Mycobacterium Tuberculosis Infections Therapeutics - Recent Pipeline Updates, H1 2014 61
Mycobacterium Tuberculosis Infections - Dormant Projects, H1 2014 63

List of Figures

Number of Products under Development for Mycobacterium Tuberculosis Infections, H1 2014 9
Number of Products under Development for Mycobacterium Tuberculosis Infections - Comparative Analysis, H1 2014 10
Number of Products under Development by Companies, H1 2014 11
Number of Products under Investigation by Universities/Institutes, H1 2014 13
Comparative Analysis by Early Stage Products, H1 2014 16
Assessment by Monotherapy Products, H1 2014 27
Number of Products by Top 10 Target, H1 2014 29
Number of Products by Stage and Top 10 Target, H1 2014 30
Number of Products by Top 10 Mechanism of Action, H1 2014 31
Number of Products by Stage and Top 10 Mechanism of Action, H1 2014 32
Number of Products by Top 10 Route of Administration, H1 2014 33
Number of Products by Stage and Top 10 Route of Administration, H1 2014 34
Number of Products by Top 10 Molecule Type, H1 2014 35
Number of Products by Stage and Top 10 Molecule Type, H1 2014 36

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