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Bioinformatics: Technologies and Global Markets

  • January 2016
  • -
  • BCC Research
  • -
  • 158 pages

This BCC Research report provides a comprehensive analysis of the bioinformatic market by reviewing the recent advances in high throughput ‘omic platforms and computer enabled tools that drive the field forward. Includes forecast through 2019.

Use this report to:

Identify the challenges and opportunities that exist in the bioinformatic market.
Analyze industry service providers and software solution developers, as well as IT and bioinformatics service providers.
Analyze recent advances in ‘omic technologies and examines their impact on the bioinformatic market.
Learn about the ways in which bioinformatics has been utilized by the pharma and biotech industry to streamline the research and development (R&D) process and improve efficiencies

Highlights

The global bioinformatic market was $3.6 billion and $4.1billion in 2013 and 2014, respectively. This market is expected to reach $8.0 billion in 2019 from $4.7 billion in 2015 at a compound annual growth rate of 14.2% for the period 2014-2019.
North American market is expected to grow from nearly $2.6 billion in 2015 to $4.5 billion in 2019 at a CAGR of 15.2% for the period 2014-2019.
European market will grow from nearly $1.1 billion in 2015 to $1.7 billion in 2019 at a CAGR of 12.0% for the period 2014-2019.

STUDY GOALS AND OBJECTIVES

BCC Research’s goal for this study is to provide a comprehensive analysis of the bioinformatic market by reviewing the recent advances in high-throughput ‘omic platforms and computer-enabled tools that drive the field forward. It examines the market trends and provides analysis regarding industry service providers and software
solution developers, as well as IT and bioinformatics service providers that support the pharma and biotech industry.

The report’s main focus is to identify the challenges and opportunities that exist in the bioinformatic market following the adoption of high-throughput technologies such as next-generation sequencing (NGS), the analysis of big data and the emergence of cloud-based solutions. It identifies innovative companies and technologies that are
moving the field forward and enabling scientists to search for elusive pieces of information that will improve diagnosis and treatment with precision medicines.

REASONS FOR DOING THE STUDY

Since scientists unraveled the blueprint of the human genome more that 10 years ago, they have been exploring new ways to utilize ‘omic data to understand more complex diseases. Researchers are keen to analyze as many different types of data as possible to gain a better understanding of that which is happening at the cellular and molecular levels. Service providers have developed new analytical tools and information technology (IT) infrastructures to enable scientists to interrogate complex data sources and quickly and efficiently disseminate information for better decision making to achieve this goal.

More recently, improvements in cloud computing capabilities and advances in data analysis software services have helped to expand the evaluation of available datasets, allowing researchers to build systems biology models of various diseases. There has recently been a massive shift in the way people do computing in part due to the
availability of cloud computing and the growth in NGS technologies, and as a result, service providers are now offering more cloud-based solutions on a pay-as-you-go or fee-for-service manner to suit the budgets of both small and larger business.

SCOPE OF REPORT

The scope of the study encompasses the global bioinformatic market based on geography, category and application. It provides a detailed analysis of recent advances in ‘omic technologies and examines their impact on the bioinformatic market. It discusses the ways in which bioinformatics has been utilized by the pharma and
biotech industry to streamline the research and development (R&D) process and improve efficiencies. It provides a detailed analysis of leading countries, companies and technologies that will drive the field forward.

Table Of Contents

Bioinformatics: Technologies and Global Markets
CHAPTER 1 INTRODUCTION 2
STUDY GOALS AND OBJECTIVES 2
REASONS FOR DOING THE STUDY 2
SCOPE OF REPORT 2
INTENDED AUDIENCE 3
INFORMATION SOURCES 3
ANALYST'S CREDENTIALS 3
RELATED BCC RESEARCH REPORTS 4
BCC RESEARCH WEBSITE 4
DISCLAIMER 4
CHAPTER 2 EXECUTIVE SUMMARY 6
SUMMARY TABLE GLOBAL BIOINFORMATIC MARKET BY REGION, THROUGH 2019 ($
MILLIONS) 6
SUMMARY FIGURE GLOBAL BIOINFORMATIC MARKET BY REGION, 2013-2019 ($
MILLIONS) 7
CHAPTER 3 BIG DATA: WHAT TO DO WITH IT? 10
GOAL OF BIOINFORMATICS 10
FIGURE 1 RELATIONSHIP OF BIOINFORMATICS WITH 'OMIC TECHNOLOGIES 10
BIOLOGICAL DATA SOURCES 10
BIOINFORMATICS IN SYSTEMS BIOLOGY 11
FIGURE 2 SCHEMATIC REPRESENTATION OF BIOLOGY SYSTEMS AND
TRANSLATIONAL BIOINFORMATICS 11
PRECISION MEDICINE 12
FIGURE 3 PRINCIPLES OF PRECISION MEDICINE 14
BIOINFORMATICS IN DRUG DEVELOPMENT 14
FIGURE 4 APPLICATIONS OF BIOINFORMATICS ON DRUG DEVELOPMENT 15
CHEMINFORMATICS 15
NEXT-GENERATION SEQUENCING 16
METAGENOMICS 16
DATA MANAGEMENT SYSTEMS 17
MARKET TRENDS 17
TABLE 1 U.S. FOOD AND DRUG ADMINISTRATION AND EUROPEAN MEDICINES
AGENCY DRUG APPROVALS, 2009-2014 17
PRECISION MEDICINE AND BIOMARKER IDENTIFICATION 18
CLOUD-BASED SOLUTIONS 18
SHIFT TOWARD VALUE-BASED CARE 19
MARKET CHALLENGES 19
DATA INTEGRATION 19
DATA RELIABILITY AND STANDARDIZATION 20
END-TO-END WORKFLOWS 20
CURRENT MARKET 21
MARKET BY REGION 21
TABLE 2 GLOBAL BIOINFORMATIC MARKET BY REGION, THROUGH 2019 ($
MILLIONS) 21
MARKET BY CATEGORY 21
PUBLIC FUNDING 22
TABLE 3 PUBLIC FUNDING PROGRAMS, 2005-2014 23
PRIVATE FUNDING 24
TABLE 4 GLOBAL BIOINFORMATIC MARKET BY CATEGORY, THROUGH 2019 ($
MILLIONS) 24
MARKET BY APPLICATION 25
TABLE 5 GLOBAL BIOINFORMATIC MARKET BY APPLICATION, THROUGH 2019 ($
MILLIONS) 26
CHAPTER 4 BIOINFORMATICS: DATA GENERATION AND DATA MANAGEMENT 28
INFORMATION OVERLOAD 28
FIGURE 5 FOUR DIMENSIONS OF BIG DATA 28
DATA VOLUME 29
DATA VARIETY 29
DATA VELOCITY 29
DATA VERACITY 30
TECHNOLOGIES BEHIND BIG DATA GENERATION 30
GENOMIC ADVANCES 30
SEQUENCING GENOMICS 30
Metagenomics 31
Exponential Growth in Next-Generation Sequencing Software Tools 31
FUNCTIONAL GENOMICS 32
Functional Genomics in Drug Discovery 32
CRISPR Cas9 System 32
PROTEOMIC ADVANCES 33
QUALITATIVE PROTEOMICS 33
QUANTITATIVE PROTEOMICS 33
STRUCTURAL PROTEOMICS 34
Protein Structure Initiative 34
Structural Genomic Consortium 34
INTERACTION PROTEOMICS 35
Application in Drug Discovery 35
Bottom-Up versus Top-Down Proteomics 36
FIGURE 6 TOP-DOWN PROTEOMIC APPROACH 36
Emergence of Glycomics 36
Human Proteome Organization and the Human Proteome Project
Initiative 37
TRANSCRIPTOMIC ADVANCES 37
RNA Sequencing 38
Co-Expression and Single-Cell RNA-Seq 38
METABOLOMIC ADVANCES 39
TABLE 6 COMMERCIALLY AVAILABLE METABOLOMIC SOFTWARE 40
TABLE 7 OPEN-ACCESS TOOLS FOR COMPLEX LIQUID CHROMATOGRAPHY-MASS
SPECTROMETRY DATA ANALYSIS 40
CHEMINFORMATIC ADVANCES 41
TABLE 8 CHEMINFORMATIC SOFTWARE SOLUTIONS FOR DRUG RESEARCH AND
DEVELOPMENT 42
EMERGING TECHNOLOGIES 43
METAGENOMIC ADVANCES 43
TABLE 9 BIOINFORMATIC TOOLS FOR METAGENOMIC STUDIES 44
EPIGENOMIC ADVANCES 46
PHARMACOGENOMIC ADVANCES 48
PHARMACOGENOMICS AND PRECISION MEDICINE 48
VALUE-BASED DECISIONS 48
PHARMACOGENOMICS AND RESEARCH AND DEVELOPMENT 49
TABLE 10 BIOINFORMATIC TOOLS FOR PHARMACOGENOMIC STUDIES 49
INTERNATIONAL SERIOUS ADVERSE EVENTS CONSORTIUM 50
PHARMACOGENOMIC SOFTWARE 50
TABLE 11 BIOINFORMATIC TOOLS FOR PHARMACOGENOMIC SOFTWARE 50
TOXICOGENOMIC ADVANCES 51
TOXCAST COMPUTATIONAL TOXICOLOGY RESEARCH PROGRAM 52
CUSTOMIZED TOXICOGENOMIC PLATFORMS 52
DATABASE MANAGEMENT SERVICES 52
TABLE 12 ARCHIVAL DATABASES 53
TABLE 13 CURATIVE DATABASES 55
TABLE 14 COMMERCIALLY AVAILABLE DATABASES 57
MARKET DYNAMICS 58
CHAPTER 5 BIOINFORMATICS: DATA ANALYSIS AND SOFTWARE 60
INTRODUCTION 60
DATA ANALYSIS SOFTWARE 60
FIGURE 7 EUROPEAN BIOINFORMATIC INSTITUTE SOFTWARE SOLUTIONS 60
TABLE 15 SOFTWARE FOR BIOLOGICAL ANALYSIS 62
TABLE 16 POPULAR COMMERCIALLY AVAILABLE BIOINFORMATIC PROGRAMS FOR
NEXT-GENERATION SEQUENCING ANALYSIS 67
BIOSIMULATION MODELS 68
MARKET ANALYSIS 69
CHAPTER 6 BIOINFORMATICS: DATA PROCESSING AND STORAGE 72
MIND THE GAP 72
FIGURE 8 EVOLUTION OF INFORMATION TECHNOLOGY INFRASTRUCTURE 73
INFORMATION TECHNOLOGY INFRASTRUCTURE 73
TABLE 17 TOP 20 HARDWARE COMPANIES, 2010 ($MM/%) 74
HIGH-PERFORMANCE COMPUTING 74
TABLE 18 TOP SUPERCOMPUTERS, AS OF 2015 75
HIGH-PERFORMANCE COMPUTER CLUSTERS 76
CLOUD COMPUTING 77
FIGURE 9 SCHEMATIC REPRESENTATION OF CLOUD COMPUTING SERVICES 77
DATA AS A SERVICE 78
INFRASTRUCTURE AS A SERVICE 79
PLATFORM AS A SERVICE 79
SOFTWARE AS A SERVICE 79
TABLE 19 SOFTWARE AS A SERVICE RESOURCE 79
SECURITY AS A SERVICE 80
CLOUD COMPUTING CHALLENGES 80
FUTURE OF CLOUD COMPUTING 81
MARKET ANALYSIS 82
CHAPTER 7 BIOINFORMATIC APPLICATIONS IN PHARMACEUTICAL RESEARCH AND
DEVELOPMENT 84
INTRODUCTION 84
TABLE 20 LEADING BIOINFORMATICS DATABASES 85
DRUG DISCOVERY AND DEVELOPMENT PROCESS 86
FIGURE 10 PHASES IN THE DRUG DISCOVERY AND DEVELOPMENT PROCESS 86
PRECLINICAL RESEARCH: DRUG DISCOVERY PHASE 87
TARGET IDENTIFICATION 88
TARGET VALIDATION 88
Role of Bioinformatics in Target Identification and Validation 89
TABLE 21 LEADING DRUG TARGET DATABASES 89
LEAD IDENTIFICATION 90
COMPUTER-AIDED DRUG DESIGN 91
FIGURE 11 BIOINFORMATIC INTERDISCIPLINARY NATURE 91
TABLE 22 COMPUTER SIMULATION PLATFORMS 92
LEAD OPTIMIZATION 93
CLINICAL RESEARCH: DRUG DEVELOPMENT 94
PRECLINICAL EXPERIMENTS 94
LABORATORY INFORMATION MANAGEMENT SYSTEMS 94
TABLE 23 LEADING LABORATORY INFORMATION MANAGEMENT SYSTEM
PROVIDERS 95
ELECTRONIC LABORATORY NOTEBOOKS 96
FIGURE 12 INFORMATION SYSTEMS WITHIN THE LABORATORY ARCHITECTURE 96
TABLE 24 ELECTRONIC NOTEBOOKS USED WITHIN THE RESEARCH AND
DEVELOPMENT ENVIRONMENT 98
TABLE 25 ELECTRONIC LABORATORY NOTEBOOKS USED WITHIN SPECIFIC AREAS
OF BIOLOGY 99
INVESTIGATIONAL NEW DRUG APPLICATION 99
CLINICAL TRIALS 100
BIOINFORMATICS IN CLINICAL TRIAL DESIGN AND DATA COLLATION 101
TABLE 26 LEADING ABSORPTION, DISTRIBUTION, METABOLISM, EXCRETION AND
TOXICITY PREDICTION TOOLS 102
NEW DRUG APPLICATION 102
NEW DRUG APPLICATION APPROVAL 103
TABLE 27 DRUG DEVELOPMENT PROCESS OVERVIEW 103
POST-LAUNCH ONGOING STUDIES AND PHASE IV CLINICAL TRIALS 104
ELECTRONIC HEALTH RECORDS 104
TABLE 28 LEADING ELECTRONIC HEALTH RECORD PROVIDERS, 2013 105
MOBILE HEALTH TECHNOLOGIES 105
TABLE 29 MEDICAL APPLICATIONS FOR HEALTHCARE PROFESSIONALS 106
RECENT PHARMACEUTICAL AND BIOINFORMATIC ALLIANCES AND
PARTNERSHIPS 106
TABLE 30 PHARMACEUTICAL AND BIOINFORMATIC PARTNERSHIPS AND ALLIANCES 107
CONCLUSIONS 109
CHAPTER 8 MARKET TRENDS AND ANALYSIS 111
NORTH AMERICA 111
TABLE 31 NORTH AMERICAN BIOINFORMATIC MARKET BY REGION, THROUGH 2019
($ MILLIONS) 111
UNITED STATES 111
TABLE 32 LEADING BIOINFORMATIC COMPANIES IN THE U.S. 112
TABLE 33 TOP 15 VENTURE CAPITAL COMPANIES MOST ACTIVE IN THE LIFE
SCIENCE SECTOR, THROUGH 2012 114
TABLE 34 U.S. BIOINFORMATIC MARKET BY APPLICATION, THROUGH 2019 ($
MILLIONS) 115
TABLE 35 U.S. BIOINFORMATIC MARKET BY CATEGORY, THROUGH 2019 ($
MILLIONS) 116
CANADA 116
TABLE 36 CANADIAN BIOINFORMATIC MARKET BY CATEGORY, THROUGH 2019 ($
MILLIONS) 117
TABLE 37 LEADING CANADIAN BIOINFORMATIC COMPANIES 117
TABLE 38 CANADIAN BIOINFORMATIC MARKET BY APPLICATION, THROUGH 2019 ($
MILLIONS) 118
EUROPE 118
TABLE 39 EUROPEAN BIOINFORMATIC MARKET BY REGION, THROUGH 2019 ($
MILLIONS) 119
TABLE 40 LEADING EUROPEAN BIOINFORMATIC COMPANIES 119
U.K. 120
TABLE 41 U.K. BIOINFORMATIC MARKET BY CATEGORY,THROUGH 2019 ($
MILLIONS) 122
TABLE 42 U.K. BIOINFORMATIC MARKET BY APPLICATION,THROUGH 2019 ($
MILLIONS) 122
GERMANY 122
TABLE 43 GERMAN BIOINFORMATIC MARKET BY CATEGORY,THROUGH 2019 ($
MILLIONS) 123
TABLE 44 GERMAN BIOINFORMATIC MARKET BY APPLICATION,THROUGH 2019 ($
MILLIONS) 124
SWITZERLAND 124
TABLE 45 SWISS BIOINFORMATIC MARKET BY CATEGORY,THROUGH 2019 ($
MILLIONS) 125
TABLE 46 SWISS BIOINFORMATIC MARKET BY APPLICATION,THROUGH 2019 ($
MILLIONS) 125
ASIA-PACIFIC 126
TABLE 47 ASIA-PACIFIC BIOINFORMATIC MARKET BY REGION,THROUGH 2019 ($
MILLIONS) 126
INDIA 126
TABLE 48 INDIAN BIOINFORMATIC MARKET BY CATEGORY,THROUGH 2019 ($
MILLIONS) 126
FIGURE 13 KEY AREAS OF RESEARCH UTILIZING BIOINFORMATICS 128
TABLE 49 LEADING INDIAN BIOINFORMATIC COMPANIES 128
TABLE 50 INDIAN BIOINFORMATIC MARKET BY APPLICATION,THROUGH 2019 ($
MILLIONS) 130
CHINA 130
TABLE 51 CHINESE BIOINFORMATIC MARKET BY CATEGORY,THROUGH 2019 ($
MILLIONS) 132
TABLE 52 CHINESE BIOINFORMATIC MARKET BY APPLICATION,THROUGH 2019 ($
MILLIONS) 133
CONCLUSIONS 133
CHAPTER 9 COMPANY PROFILES 136
3RD MILLENNIUM INC. 136
ASTRID BIOSCIENCE GMBH 136
BIOBASE GMBH 137
BIOMATTERS LTD. 138
CLC BIOINFORMATICS 138
CONEXIO GENOMICS PRIVATE LTD. 139
COMPUGEN LTD. 139
DASSAULT SYSTEMES SA 140
DNASTAR INC. 141
GEOSPIZA INC. 141
GENOMATIX SOFTWARE GMBH 142
GVK BIOSCIENCES PRIVATE LTD. 142
GENOLOGICS LIFESCIENCES SOFTWARE INC. 143
GENEDATA AG 143
GENEVA BIOFORMATICS (GENEBIO) SA 144
GNS HEALTHCARE INC. 145
ILLUMINA INC. 145
MOLECULAR CONNECTIONS PRIVATE LTD. 146
MOLECULAR NETWORKS GMBH 146
NONLINEAR DYNAMICS LTD. 147
OCIMUM BIOSOLUTIONS LTD. 148
PERKIN ELMER INFORMATICS INC. 148
PERSONALIS INC. 149
SMARTGENE SERVICES SARL 150
REAL TIME GENOMICS INC. 150
CHAPTER 10 APPENDIX ONE: ACRONYMS 153
CHAPTER 11 REFERENCES 156
ENDNOTES 168

LIST OF TABLES

SUMMARY TABLE GLOBAL BIOINFORMATIC MARKET BY REGION, THROUGH 2019 ($
MILLIONS) 6
TABLE 1 U.S. FOOD AND DRUG ADMINISTRATION AND EUROPEAN MEDICINES
AGENCY DRUG APPROVALS, 2009-2014 17
TABLE 2 GLOBAL BIOINFORMATIC MARKET BY REGION, THROUGH 2019 ($ MILLIONS) 21
TABLE 3 PUBLIC FUNDING PROGRAMS, 2005-2014 23
TABLE 4 GLOBAL BIOINFORMATIC MARKET BY CATEGORY, THROUGH 2019 ($
MILLIONS) 24
TABLE 5 GLOBAL BIOINFORMATIC MARKET BY APPLICATION, THROUGH 2019 ($
MILLIONS) 26
TABLE 6 COMMERCIALLY AVAILABLE METABOLOMIC SOFTWARE 40
TABLE 7 OPEN-ACCESS TOOLS FOR COMPLEX LIQUID CHROMATOGRAPHY-MASS
SPECTROMETRY DATA ANALYSIS 40
TABLE 8 CHEMINFORMATIC SOFTWARE SOLUTIONS FOR DRUG RESEARCH AND
DEVELOPMENT 42
TABLE 9 BIOINFORMATIC TOOLS FOR METAGENOMIC STUDIES 44
TABLE 10 BIOINFORMATIC TOOLS FOR PHARMACOGENOMIC STUDIES 49
TABLE 11 BIOINFORMATIC TOOLS FOR PHARMACOGENOMIC SOFTWARE 50
TABLE 12 ARCHIVAL DATABASES 53
TABLE 13 CURATIVE DATABASES 55
TABLE 14 COMMERCIALLY AVAILABLE DATABASES 57
TABLE 15 SOFTWARE FOR BIOLOGICAL ANALYSIS 62
TABLE 16 POPULAR COMMERCIALLY AVAILABLE BIOINFORMATIC PROGRAMS FOR
NEXT-GENERATION SEQUENCING ANALYSIS 67
TABLE 17 TOP 20 HARDWARE COMPANIES, 2010 ($MM/%) 74
TABLE 18 TOP SUPERCOMPUTERS, AS OF 2015 75
TABLE 19 SOFTWARE AS A SERVICE RESOURCE 79
TABLE 20 LEADING BIOINFORMATICS DATABASES 85
TABLE 21 LEADING DRUG TARGET DATABASES 89
TABLE 22 COMPUTER SIMULATION PLATFORMS 92
TABLE 23 LEADING LABORATORY INFORMATION MANAGEMENT SYSTEM PROVIDERS 95
TABLE 24 ELECTRONIC NOTEBOOKS USED WITHIN THE RESEARCH AND
DEVELOPMENT ENVIRONMENT 98
TABLE 25 ELECTRONIC LABORATORY NOTEBOOKS USED WITHIN SPECIFIC AREAS OF
BIOLOGY 99
TABLE 26 LEADING ABSORPTION, DISTRIBUTION, METABOLISM, EXCRETION AND
TOXICITY PREDICTION TOOLS 102
TABLE 27 DRUG DEVELOPMENT PROCESS OVERVIEW 103
TABLE 28 LEADING ELECTRONIC HEALTH RECORD PROVIDERS, 2013 105
TABLE 29 MEDICAL APPLICATIONS FOR HEALTHCARE PROFESSIONALS 106
TABLE 30 PHARMACEUTICAL AND BIOINFORMATIC PARTNERSHIPS AND ALLIANCES 107
TABLE 31 NORTH AMERICAN BIOINFORMATIC MARKET BY REGION, THROUGH 2019
($ MILLIONS) 111
TABLE 32 LEADING BIOINFORMATIC COMPANIES IN THE U.S. 112
TABLE 33 TOP 15 VENTURE CAPITAL COMPANIES MOST ACTIVE IN THE LIFE SCIENCE
SECTOR, THROUGH 2012 114
TABLE 34 U.S. BIOINFORMATIC MARKET BY APPLICATION, THROUGH 2019 ($
MILLIONS) 115
TABLE 35 U.S. BIOINFORMATIC MARKET BY CATEGORY, THROUGH 2019 ($ MILLIONS) 116
TABLE 36 CANADIAN BIOINFORMATIC MARKET BY CATEGORY, THROUGH 2019 ($
MILLIONS) 117
TABLE 37 LEADING CANADIAN BIOINFORMATIC COMPANIES 117
TABLE 38 CANADIAN BIOINFORMATIC MARKET BY APPLICATION, THROUGH 2019 ($
MILLIONS) 118
TABLE 39 EUROPEAN BIOINFORMATIC MARKET BY REGION, THROUGH 2019 ($
MILLIONS) 119
TABLE 40 LEADING EUROPEAN BIOINFORMATIC COMPANIES 119
TABLE 41 U.K. BIOINFORMATIC MARKET BY CATEGORY,THROUGH 2019 ($ MILLIONS) 122
TABLE 42 U.K. BIOINFORMATIC MARKET BY APPLICATION,THROUGH 2019 ($
MILLIONS) 122
TABLE 43 GERMAN BIOINFORMATIC MARKET BY CATEGORY,THROUGH 2019 ($
MILLIONS) 123
TABLE 44 GERMAN BIOINFORMATIC MARKET BY APPLICATION,THROUGH 2019 ($
MILLIONS) 124
TABLE 45 SWISS BIOINFORMATIC MARKET BY CATEGORY,THROUGH 2019 ($
MILLIONS) 125
TABLE 46 SWISS BIOINFORMATIC MARKET BY APPLICATION,THROUGH 2019 ($
MILLIONS) 125
TABLE 47 ASIA-PACIFIC BIOINFORMATIC MARKET BY REGION,THROUGH 2019 ($
MILLIONS) 126
TABLE 48 INDIAN BIOINFORMATIC MARKET BY CATEGORY,THROUGH 2019 ($
MILLIONS) 126
TABLE 49 LEADING INDIAN BIOINFORMATIC COMPANIES 128
TABLE 50 INDIAN BIOINFORMATIC MARKET BY APPLICATION,THROUGH 2019 ($
MILLIONS) 130
TABLE 51 CHINESE BIOINFORMATIC MARKET BY CATEGORY,THROUGH 2019 ($
MILLIONS) 132
TABLE 52 CHINESE BIOINFORMATIC MARKET BY APPLICATION,THROUGH 2019 ($
MILLIONS) 133

LIST OF FIGURES

SUMMARY FIGURE GLOBAL BIOINFORMATIC MARKET BY REGION, 2013-2019 ($
MILLIONS) 7
FIGURE 1 RELATIONSHIP OF BIOINFORMATICS WITH 'OMIC TECHNOLOGIES 10
FIGURE 2 SCHEMATIC REPRESENTATION OF BIOLOGY SYSTEMS AND
TRANSLATIONAL BIOINFORMATICS 11
FIGURE 3 PRINCIPLES OF PRECISION MEDICINE 14
FIGURE 4 APPLICATIONS OF BIOINFORMATICS ON DRUG DEVELOPMENT 15
FIGURE 5 FOUR DIMENSIONS OF BIG DATA 28
FIGURE 6 TOP-DOWN PROTEOMIC APPROACH 36
FIGURE 7 EUROPEAN BIOINFORMATIC INSTITUTE SOFTWARE SOLUTIONS 60
FIGURE 8 EVOLUTION OF INFORMATION TECHNOLOGY INFRASTRUCTURE 73
FIGURE 9 SCHEMATIC REPRESENTATION OF CLOUD COMPUTING SERVICES 77
FIGURE 10 PHASES IN THE DRUG DISCOVERY AND DEVELOPMENT PROCESS 86
FIGURE 11 BIOINFORMATIC INTERDISCIPLINARY NATURE 91
FIGURE 12 INFORMATION SYSTEMS WITHIN THE LABORATORY ARCHITECTURE 96
FIGURE 13 KEY AREAS OF RESEARCH UTILIZING BIOINFORMATICS 128

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