STUDY OBJECTIVES

BCC’s aim in conducting this study is to offer synopsis of the current and future characteristics of the global market for optical coherence tomography (OCT). The key objective is to present a comprehensive analysis and future trend and research of OCT as an important tool for the usage of this technique in imaging.

This report explores present and future different OCT techniques and their usage and developments within the OCT market. This report includes different types of OCT techniques such as time domain and large-field high-speed polarization sensitive system, Fourier domain or spectral domain and time-encoded frequency domain or swept source, full-field optical coherence and optical delay scanning. The improvisation of the market, the setbacks and the needs of the market are discussed in this report. The classification, new developments and usage of these types of techniques are also portrayed in this report.

A detailed analysis of the OCT industry has been conducted. Revenues are broken down by region. Sales figures are estimated for the five-year period from 2012 through 2017.
Applications for OCT are also discussed in this report, with an emphasis of the usage of this technique in different therapeutic categories and various other industries. This report also covers significant patents and their allotments in each category.

Acquisition strategies and collaborations by companies are also covered in this report. This study also discusses the strength and weaknesses of each type/ technology in light of the new technologies, growing competition and changing customer needs.

REASONS FOR DOING THIS STUDY

Extensive research in the OCT field has revealed its current usage in various applications and its usage in the future. The report also covers current research and developments going on in this field. This report also discusses the usage of OCT techniques over other current imaging techniques such as magnetic resonance imaging and ultrasound imaging. Researchers are exploring the advantages of OCT in newer areas, leading to the increased usage and consumption of these techniques. R&D spending, patents and research in this field are giving a new direction. The advancements, new product launches and the early disease detection awareness influenced the market to grow in the foreseeable future. This study looks at almost all of the systems affected by these factors.

CONTRIBUTIONS OF THE STUDY AND INTENDED AUDIENCE

This study contributes to the areas of market growth in OCT manufacturers and users. Pharmaceutical, biotechnical companies, research institutes and analytical/diagnostic institutes will find this study to be of interest.

SCOPE OF THE STUDY

The scope of this study embraces OCT in medical and other markets. BCC analyzed each market and its applications, regulatory environment, technology, market projections and market shares. Technological issues include the latest trends and developments. The emerging markets for OCT include countries such as India, China, Japan, Korea, Taiwan, Africa, Australia, New Zealand, etc.

METHODOLOGY

Both primary and secondary research methodologies were used in preparing this study. BCC conducted a comprehensive literature search, which included technical newsletters and journals, and many other sources. Data were collected through interviews and correspondence with manufacturers of OCT technical experts. Projections were based on estimates such as the current number of end users, potential end users, mergers and acquisitions and market trends.

INFORMATION SOURCES

Many companies were surveyed to obtain data for this study, including manufacturers and end users of OCT. Data were gathered from various industry sources. BCC spoke with officials within the industry and consulted newsletters, company literature, product literature and a host of technical articles, journals, indexes and abstracts. Exhaustive investigations of databases by key terminology were completed. In addition, data were compiled from current financial, trade and government sources.

ABOUT THE AUTHOR

A team of professionals in the biotechnology industry carried out this study. The project manager was Shalini S. Dewan, who holds a Master’s degree in pharmaceutical chemistry and has over 14 years of industry experience. Among the research topics she has covered are studies on compounds of potential pharmaceutical interest from ibuprofen and 2-naphthyl acetic acid. Shalini was awarded a Gold Medal by the Prime Minister of India for her work and has worked with top companies in India and in the U.S. Some of her other reports with BCC are: Reagents for Chromatography; Spectroscopy: An Enduring Market; Advanced Drug Delivery Systems: Technologies and Global Markets; Orthopedic Drugs, Implants and Devices; Medical Imaging Reagents and Analysis Equipment; Pharmaceutical Regulatory Industry; The Dynamic Media, Sera and Reagent Market in Biotechnology; Contract Pharmaceutical Manufacturing, Research and Packaging: Global Markets; Chiral Technology: Global Markets; Autacoids and Related Drugs: Technologies and Global Markets; Contraceptives: Technologies and Global Markets; Liver Disease Treatments: The Global Market; Hormone Replacement Therapies and Other Hormone Therapies: Global Markets; Cardiovascular Medicine: Diagnostics, Drugs and Devices; and Cancer Therapies: Technologies and Global Markets.

REPORT HIGHLIGHTS

This report provides:

• An overview of the global market for optical coherence tomography (OCT), including details on system technology segments: traditional (time domain), frequency domain, and other modes of OCT measurement.
• Analyses of global market trends, with data from 2010 to 2012, and projections of compound annual growth rates (CAGRs) through 2017.
• A breakdown of OCT formats, including office/tabletop, catheter-based, and handheld.
• Regulatory status of the devices in the U.S., EU, and other regions.
• Delineation of the major markets for the technology, including ophthalmology, cardiovascular, oncology, dermatology, and dental applications.
• Comprehensive company profiles of major players.

Table Of Contents

TABLE OF CONTENTS

CHAPTER 1 INTRODUCTION 2

STUDY OBJECTIVES 2
REASONS FOR DOING THIS STUDY 2
CONTRIBUTIONS OF THE STUDY AND INTENDED AUDIENCE 3
SCOPE OF THE STUDY 3
METHODOLOGY 3
INFORMATION SOURCES 3
ABOUT THE AUTHOR 3
RELATED BCC RESEARCH REPORTS 4
BCC ONLINE SERVICES 4
DISCLAIMER 4

CHAPTER 2 SUMMARY 6

SUMMARY TABLE GLOBAL REVENUE OF OCT MARKET, THROUGH 2017 ($ MILLIONS) 8
SUMMARY FIGURE GLOBAL REVENUE OF OCT MARKET, 2010-2017 ($ MILLIONS) 8

CHAPTER 3 OVERVIEW 10

TABLE 1 MAIN CHARACTERISTICS OF OCT 10
USES OF OPTICAL COHERENCE TOMOGRAPHY 11
TABLE 2 USES OF OPTICAL COHERENCE TOMOGRAPHY 11
ADVANTAGES AND DISADVANTAGES OF OPTICAL COHERENCE TOMOGRAPHY 11
TABLE 3 ADVANTAGES AND DISADVANTAGES OF OPTICAL COHERENCE
TOMOGRAPHY 12
APPLICATIONS OF OPTICAL COHERENCE TOMOGRAPHY 12
TABLE 4 APPLICATIONS OF OPTICAL COHERENCE TOMOGRAPHY 13
HISTORY OF OPTICAL COHERENCE TOMOGRAPHY 13
TABLE 5 HISTORICAL DEVELOPMENTS IN OPTICAL COHERENCE TOMOGRAPHY 14
CLASSIFICATION 14
TABLE 6 TYPE OF TECHNOLOGIES USED IN OPTICAL COHERENCE TOMOGRAPHY 15
TABLE 7 MODES OF IMPLEMENTATION IN OPTICAL COHERENCE TOMOGRAPHY 15
TYPES OF TECHNOLOGY 15
TRADITIONAL (TIME DOMAIN) OCT 15
POLARIZATION SENSITIVE (PS)-OCT 16
FREQUENCY DOMAIN OCT 16
Fourier or Spectral Domain OCT 17
Time-Encoded Frequency Domain OCT 17
OTHERS 18
Full-Field Optical Coherence 18
Optical Delay Scanning 18
TABLE 8 COMPARISON OF DIFFERENT OCT TECHNOLOGY 19
MODE OF IMPLEMENTATION 19
OFFICE/TABLETOP OCT 19
CATHETER-BASED OCT 20
HANDHELD OCT DEVICES 20
OCT SPECTROMETERS 21
DOPPLER OPTICAL COHERENCE TOMOGRAPHY (OCT) SYSTEM 21

CHAPTER 4 REGULATORY ASPECTS 23

NEW PRODUCTS APPROVED FROM 2008 TO 2012 24
TABLE 9 NEW OCT PRODUCTS APPROVED FROM 2008 TO 2012 24
RECALLS AND SAFETY ALERTS 27
TABLE 10 RECALLS AND SAFETY ALERTS FROM 2008 TO 2012 28

CHAPTER 5 NEW DEVELOPMENTS 30

NEW PARTNERSHIPS, MERGERS AND ACQUISITION 31
NEW PRODUCTS 32
TABLE 11 NEW OCT INNOVATIONS FROM 2008 TO 2012 33
PIPELINE PRODUCTS 34
TABLE 12 PIPELINE PRODUCTS FOR THE OCT MARKET 36

CHAPTER 6 GLOBAL MARKETS FOR OPTICAL COHERENCE TOMOGRAPHY 38

MARKET BY TYPE 39
MARKET OVERVIEW 39
MARKET REVENUE 41
TABLE 13 GLOBAL REVENUE OF OCT BY TYPE, THROUGH 2017 ($ MILLIONS) 41
FIGURE 1 GLOBAL REVENUE OF OCT BY TYPE, 2010-2017 ($ MILLIONS) 41
MARKET SHARE 42
TABLE 14 MARKET SHARES OF OCT BY TYPE, 2011 (%) 42
FIGURE 2 MARKET SHARES OF OCT BY TYPE, 2011 (%) 42
MARKET BY REGION 42
MARKET OVERVIEW 43
MARKET REVENUE 45
TABLE 15 GLOBAL REVENUE OF OCT BY REGION, THROUGH 2017 ($ MILLIONS) 45
FIGURE 3 GLOBAL REVENUE OF OCT BY REGION, 2010-2017 ($ MILLIONS) 45
MARKET SHARE 46
TABLE 16 GLOBAL MARKET SHARE OF OCT BY REGION, 2011 (%) 46
FIGURE 4 GLOBAL MARKET SHARE OF OCT BY REGION, 2011 (%) 46
MARKET FOR TIME DOMAIN OCT AND POLARIZATION SENSITIVE OCT 47
TABLE 17 GLOBAL REVENUE OF TD-OCT AND PS-OCT BY REGION, THROUGH 2017
($ MILLIONS) 47
FIGURE 5 GLOBAL REVENUE OF TD-OCT AND PS-OCT BY REGION, 2010-2017 ($
MILLIONS) 47
MARKET SHARE 48
TABLE 18 MARKET SHARE OF GLOBAL REVENUE OF TD-OCT AND PS-OCT BY
REGION, 2011 (%) 48
FIGURE 6 MARKET SHARE OF GLOBAL REVENUE OF TD-OCT AND PS-OCT BY
REGION, 2011 (%) 48
MARKET FOR FOURIER DOMAIN AND TIME-ENCODED OCT 49
TABLE 19 GLOBAL REVENUE OF FD-OCT AND TIME-ENCODED OCT BY REGION,
THROUGH 2017 ($ MILLIONS) 49
FIGURE 7 GLOBAL REVENUE OF FD-OCT AND TIME-ENCODED OCT BY REGION,
2010-2017 ($ MILLIONS) 49
MARKET SHARE 50
TABLE 20 MARKET SHARE OF FD-OCT AND TIME-ENCODED OCT BY REGION, 2011
(%) 50
FIGURE 8 MARKET SHARE OF FD-OCT AND TIME-ENCODED OCT BY REGION, 2011
(%) 50
MARKET FOR FULL-FIELD AND OPTICAL DELAY OPTICAL COHERENCE OCT 51
TABLE 21 GLOBAL REVENUE OF FF-OCT AND OD-OCT BY REGION, THROUGH 2017
($ MILLIONS) 51
FIGURE 9 GLOBAL REVENUE OF FF-OCT AND OD-OCT BY REGION, 2010-2017 ($
MILLIONS) 51
MARKET SHARE 52
TABLE 22 MARKET SHARE OF FF-OCT AND OD-OCT BY REGION, 2011 (%) 52
FIGURE 10 MARKET SHARE OF FF-OCT AND OD-OCT BY REGION, 2011 (%) 52
MARKET BY END USERS 53
MARKET OVERVIEW 54
MARKET REVENUE 59
TABLE 23 GLOBAL MARKET OF OCT BY END USERS, THROUGH 2017 ($ MILLIONS) 60
FIGURE 11 GLOBAL MARKET OF OCT BY END USERS, 2010-2017 ($ MILLIONS) 60
MARKET SHARE 61
TABLE 24 GLOBAL MARKET SHARE OF OCT BY END USERS, 2011 (%) 61
FIGURE 12 GLOBAL MARKET SHARE OF OCT BY END USERS, 2011 (%) 61

CHAPTER 7 MARKET ANALYSIS OF TIME DOMAIN AND POLARIZATION SENSITIVE

OPTICAL COHERENCE TOMOGRAPHY 63
MARKET BY TYPE 63
MARKET OVERVIEW 63
MARKET REVENUE 64
TABLE 25 GLOBAL REVENUE OF TD-OCT AND PS-OCT, THROUGH 2017 ($ MILLIONS) 64
FIGURE 13 GLOBAL REVENUE OF TD-OCT AND PS-OCT, 2010-2017 ($ MILLIONS) 64
MARKET SHARE 65
TABLE 26 MARKET SHARE OF TD-OCT AND PS-OCT BY TYPE, 2011 (%) 65
FIGURE 14 MARKET SHARE OF TD-OCT AND PS-OCT BY TYPE, 2011 (%) 65
MARKET BY REGION 66
MARKET OVERVIEW 66
MARKET REVENUE 67
Time Domain OCT 67
TABLE 27 GLOBAL REVENUE OF TD-OCT BY REGION, THROUGH 2017 ($ MILLIONS) 68
FIGURE 15 GLOBAL REVENUE OF TD-OCT BY REGION, 2010-2017 ($ MILLIONS) 68
Polarization Sensitive OCT 68
TABLE 28 GLOBAL REVENUE OF PS-OCT BY REGION, THROUGH 2017 ($ MILLIONS) 68
FIGURE 16 GLOBAL REVENUE OF PS-OCT BY REGION, 2010-2017 ($ MILLIONS) 69
MARKET SHARE 69
TABLE 29 MARKET SHARE OF PS-OCT BY REGION, 2011 (%) 70
FIGURE 17 MARKET SHARE OF PS-OCT BY REGION, 2011 (%) 70
MARKETS BY END USERS 70
TABLE 30 GLOBAL REVENUE OF PS-OCT AND TD-OCT BY END USERS, THROUGH
2017 ($ MILLIONS) 70
FIGURE 18 GLOBAL REVENUE OF PS-OCT AND TD-OCT BY END USERS, 2010-2017
($ MILLIONS) 72
PHARMACEUTICAL AND BIOTECHNOLOGY INDUSTRY 72
Market Revenue 73
TABLE 31 GLOBAL EXPENDITURE OF TD-OCT AND PS-OCT IN THE
PHARMACEUTICAL AND BIOTECHNOLOGY INDUSTRIES, THROUGH 2017 ($
MILLIONS)
73
FIGURE 19 GLOBAL EXPENDITURE OF TD-OCT AND PS-OCT IN THE
PHARMACEUTICAL AND BIOTECHNOLOGY INDUSTRIES, 2010-2017 ($ MILLIONS) 73
ENVIRONMENTAL SCIENCE INDUSTRY 74
Market Revenue 74
TABLE 32 GLOBAL EXPENDITURE OF TD-OCT AND PS-OCT IN THE ENVIRONMENTAL
SCIENCES INDUSTRY, THROUGH 2017 ($ MILLIONS) 75
FIGURE 20 GLOBAL EXPENDITURE OF TD-OCT AND PS-OCT IN THE
ENVIRONMENTAL SCIENCES INDUSTRY, 2010-2017 ($ MILLIONS) 75
FOOD AND BEVERAGE INDUSTRY 76
Market Revenue 76
TABLE 33 GLOBAL EXPENDITURE OF TD-OCT AND PS-OCT IN THE FOOD AND
BEVERAGE INDUSTRY, THROUGH 2017 ($ MILLIONS) 76
FIGURE 21 GLOBAL EXPENDITURE OF TD-OCT AND PS-OCT IN THE FOOD AND
BEVERAGE INDUSTRY, 2010-2017 ($ MILLIONS) 77
OTHER INDUSTRIES 77
Market Revenue 77
TABLE 34 GLOBAL EXPENDITURE OF TD-OCT AND PS-OCT IN OTHER INDUSTRIES,
THROUGH 2017 ($ MILLIONS) 78
FIGURE 22 GLOBAL EXPENDITURE OF TD-OCT AND PS-OCT IN OTHER INDUSTRIES,
2010-2017 ($ MILLIONS) 78
MARKET SHARE 78
TABLE 35 MARKET SHARE OF TD-OCT AND PS-OCT BY APPLICATION, 2011 (%) 79
FIGURE 23 MARKET SHARE OF TD-OCT AND PS-OCT BY APPLICATION, 2011 (%) 79
INDUSTRY STRUCTURE 79
TIME DOMAIN OPTICAL COHERENCE TOMOGRAPHY 79
Market Leaders 79
TABLE 36 MAJOR MANUFACTURERS IN TD-OCT, 2011 80
Market Share 80
TABLE 37 MARKET SHARE FOR MANUFACTURERS IN TD-OCT, 2011 (%) 80
FIGURE 24 MARKET SHARE FOR MANUFACTURERS IN TD-OCT, 2011 (%) 80
POLARIZATION SENSITIVE OPTICAL COHERENCE TOMOGRAPHY 81
Market Leaders 81
TABLE 38 MAJOR MANUFACTURERS IN PS-OCT, 2011 81
Market Share 81
TABLE 39 MARKET SHARE FOR THE MANUFACTURERS IN PS-OCT, 2011 (%) 81
FIGURE 25 MARKET SHARE FOR THE MANUFACTURERS IN PS-OCT, 2011 (%) 81

CHAPTER 8 MARKET ANALYSIS FOR FOURIER DOMAIN AND TIME-ENCODED OCT 84

MARKET BY TYPE 84
MARKET OVERVIEW 85
MARKET REVENUE 85
TABLE 40 GLOBAL REVENUE OF FD-OCT AND TIME-ENCODED OCT BY TYPE,
THROUGH 2017 ($ MILLIONS) 86
FIGURE 26 GLOBAL REVENUE OF FD-OCT AND TIME-ENCODED OCT BY TYPE,
2010-2017 ($ MILLIONS) 86
MARKET SHARE 86
TABLE 41 MARKET SHARE OF FD-OCT AND TIME-ENCODED OCT, 2011 (%) 87
FIGURE 27 MARKET SHARE OF FD-OCT AND TIME-ENCODED OCT, 2011 (%) 87
MARKET BY REGION 87
MARKET OVERVIEW 87
MARKET REVENUE 88
TABLE 42 GLOBAL REVENUE OF FD-OCT AND TIME-ENCODED OCT BY REGION,
THROUGH 2017 ($ MILLIONS) 89
FIGURE 28 GLOBAL REVENUE OF FD-OCT AND TIME-ENCODED OCT BY REGION,
2010-2017 ($ MILLIONS) 89
FOURIER DOMAIN OCT 89
TABLE 43 GLOBAL REVENUE OF FD-OCT BY REGION, THROUGH 2017 ($ MILLIONS) 90
FIGURE 29 GLOBAL REVENUE OF FD-OCT BY REGION, 2010-2017 ($ MILLIONS) 90
TIME-ENCODED OCT 90
TABLE 44 GLOBAL REVENUE OF TIME-ENCODED OCT BY REGION, THROUGH 2017
($ MILLIONS) 91
FIGURE 30 GLOBAL REVENUE OF TIME-ENCODED OCT BY REGION, 2010-2017 ($
MILLIONS) 91
MARKET SHARE 92
TABLE 45 MARKET SHARES OF FD-OCT AND TIME-ENCODED OCT BY REGION, 2011
(%) 92
FIGURE 31 MARKET SHARES OF FD-OCT AND TIME-ENCODED OCT BY REGION,
2011 (%) 92
BY END USER 92
TABLE 46 GLOBAL REVENUE OF FD-OCT AND TIME-ENCODED OCT BY END USERS,
THROUGH 2017 ($ MILLIONS) 93
FIGURE 32 GLOBAL REVENUE OF FD-OCT AND TIME-ENCODED OCT BY END USERS,
2010-2017 ($ MILLIONS) 93
CARDIOLOGY 94
Market Revenue 94
TABLE 47 GLOBAL REVENUE OF FD-OCT AND TIME-ENCODED DOMAIN OCT IN
CARDIOLOGY, THROUGH 2017 ($ MILLIONS) 95
FIGURE 33 GLOBAL REVENUE OF FD-OCT AND TIME-ENCODED DOMAIN OCT IN
CARDIOLOGY, 2010-2017 ($ MILLIONS) 95
OPHTHALMOLOGY 96
Market Revenue 97
TABLE 48 GLOBAL REVENUE OF FD-OCT AND TIME-ENCODED OCT IN
OPHTHALMOLOGY, THROUGH 2017 ($ MILLIONS) 97
FIGURE 34 GLOBAL REVENUE OF FD-OCT AND TIME-ENCODED OCT IN
OPHTHALMOLOGY, 2010-2017 ($ MILLIONS) 97
ONCOLOGY 98
Market Revenue 98
TABLE 49 GLOBAL REVENUE OF FD-OCT AND TIME-ENCODED OCT IN ONCOLOGY,
THROUGH 2017 ($ MILLIONS) 98
FIGURE 35 GLOBAL REVENUE OF FD-OCT AND TIME-ENCODED OCT IN ONCOLOGY,
2010-2017 ($ MILLIONS) 99
OTHERS 99
Market Revenue 100
TABLE 50 GLOBAL REVENUE OF FD-OCT AND TIME-ENCODED OCT IN OTHER
SECTORS, THROUGH 2017 ($ MILLIONS) 100
FIGURE 36 GLOBAL REVENUE OF FD-OCT AND TIME-ENCODED OCT IN OTHER
SECTORS, 2010-2017 ($ MILLIONS) 101
MARKET SHARE 101
TABLE 51 MARKET SHARE OF FD-OCT AND TIME-ENCODED OCT, 2011 (%) 101
FIGURE 37 MARKET SHARE OF FD-OCT AND TIME-ENCODED OCT, 2011 (%) 101
INDUSTRY STRUCTURE 102
FOURIER DOMAIN OCT 102
Market Leaders 102
TABLE 52 MAJOR MANUFACTURERS IN FOURIER OR SPECTRAL DOMAIN OCT, 2011 102
Market Shares 103
TABLE 53 MARKET SHARE OF THE MANUFACTURERS IN FOURIER OR SPECTRAL
DOMAIN OCT, 2011 (%) 103
FIGURE 38 MARKET SHARE OF THE MANUFACTURERS IN FOURIER OR SPECTRAL
DOMAIN OCT, 2011 (%) 103
TIME-ENCODED OCT 104
Market Leaders 104
TABLE 54 MAJOR MANUFACTURERS IN TIME-ENCODED OCT OR SS-OCT, 2011 104
Market Shares 104
TABLE 55 MARKET SHARE OF THE MANUFACTURERS OF TIME-ENCODED OCT OR
SS-OCT, 2011 (%) 104
FIGURE 39 MARKET SHARE OF THE MANUFACTURERS OF TIME-ENCODED OCT OR
SS-OCT, 2011 (%) 104

CHAPTER 9 MARKETS ANALYSIS FOR FULL-FIELD AND OPTICAL DELAY OPTICAL COHERENCE TOMOGRAPHY 107

MARKET BY TYPE 108
MARKET OVERVIEW 108
MARKET REVENUE 109
TABLE 56 GLOBAL REVENUE OF FF-OCT AND OD-OCT, THROUGH 2017 ($ MILLIONS) 109
FIGURE 40 GLOBAL REVENUE OF FF-OCT AND OD-OCT, 2010-2017 ($ MILLIONS) 109
MARKET SHARE 110
TABLE 57 MARKET SHARE OF FF-OCT AND OD-OCT BY TYPE, 2011 (%) 110
FIGURE 41 MARKET SHARE OF FF-OCT AND OD-OCT BY TYPE, 2011 (%) 110
MARKETS BY REGIONS 111
MARKET OVERVIEW 111
MARKET REVENUE 112
TABLE 58 GLOBAL REVENUE OF FF-OCT AND OD-OCT BY REGION, THROUGH 2017
($ MILLIONS) 112
FIGURE 42 GLOBAL REVENUE OF FF-OCT AND OD-OCT BY REGION, 2010-2017 ($
MILLIONS) 113
FULL-FIELD OPTICAL COHERENCE OCT 113
TABLE 59 GLOBAL REVENUE OF FF-OCT BY REGION, THROUGH 2017 ($ MILLIONS) 113
FIGURE 43 GLOBAL REVENUE OF FF-OCT BY REGION, THROUGH 2017 ($ MILLIONS) 114
OPTICAL DELAY OCT 114
TABLE 60 GLOBAL REVENUE OF OD-OCT BY REGION, THROUGH 2017 ($ MILLIONS) 114
FIGURE 44 GLOBAL REVENUE OF OD-OCT BY REGION, 2010-2017 ($ MILLIONS) 114
MARKET SHARE 115
TABLE 61 MARKET SHARE OF FF-OCT AND OD-OCT BY REGION, 2011 (%) 115
FIGURE 45 MARKET SHARE OF FF-OCT AND OD-OCT BY REGION, 2011 (%) 115
MARKETS BY END USERS 116
TABLE 62 GLOBAL REVENUE OF FF-OCT AND OD-OCT BY END USERS, THROUGH
2017 ($ MILLIONS) 117
FIGURE 46 GLOBAL REVENUE OF FF-OCT AND OD-OCT BY END USERS, 2010-2017
($ MILLIONS) 117
ENDOSCOPY 118
Market Revenue 118
TABLE 63 GLOBAL REVENUE OF FF-OCT AND OD-OCT IN ENDOSCOPY, THROUGH
2017 ($ MILLIONS) 119
FIGURE 47 GLOBAL REVENUE OF FF-OCT AND OD-OCT IN ENDOSCOPY, 2010-2017
($ MILLIONS) 119
ONCOLOGY 119
Market Revenue 120
TABLE 64 GLOBAL REVENUE OF FF-OCT AND OD-OCT IN ONCOLOGY, THROUGH
2017 ($ MILLIONS) 120
FIGURE 48 GLOBAL REVIEW OF FF-OCT AND OD-OCT IN ONCOLOGY, 2010-2017 ($
MILLIONS) 121
INTERSTITIAL CELL STUDIES 121
Market Revenue 122
TABLE 65 GLOBAL EXPENDITURE OF FF-OCT AND OD-OCT IN INTERSTITIAL CELL
STUDIES, THROUGH 2017 ($ MILLIONS) 122
FIGURE 49 GLOBAL EXPENDITURE OF FF-OCT AND OD-OCT IN INTERSTITIAL CELL
STUDIES, 2010-2017 ($ MILLIONS) 123
OTHERS 123
Market Revenue 124
TABLE 66 GLOBAL EXPENDITURE OF FF-OCT AND OD-OCT IN OTHER CATEGORIES,
THROUGH 2017 ($ MILLIONS) 124
FIGURE 50 GLOBAL EXPENDITURE OF FF-OCT AND OD-OCT IN OTHER CATEGORIES,
2010-2017 ($ MILLIONS) 125
MARKET SHARE 125
TABLE 67 MARKET SHARE OF FF-OCT AND OD-OCT BY END USERS, 2011 (%) 125
FIGURE 51 MARKET SHARE OF FF-OCT AND OD-OCT BY END USERS, 2011 (%) 125
INDUSTRY STRUCTURE 126
FULL-FIELD OPTICAL COHERENCE TOMOGRAPHY 126
Market Leaders 126
TABLE 68 MAJOR MANUFACTURERS IN FF-OCT, 2011 126
Market Share 126
TABLE 69 MARKET SHARE FOR MANUFACTURERS IN FF-OCT, 2011 (%) 127
FIGURE 52 MARKET SHARE FOR MANUFACTURERS IN FF-OCT, 2011 (%) 127
OPTICAL DELAY OPTICAL COHERENCE TOMOGRAPHY 127
Market Leaders 127
TABLE 70 MAJOR MANUFACTURERS IN OD-OCT, 2011 128
Market Share 128
TABLE 71 MARKET SHARE FOR MANUFACTURERS IN OD-OCT, 2011 (%) 128
FIGURE 53 MARKET SHARE FOR MANUFACTURERS IN OD-OCT, 2011 (%) 128

CHAPTER 10 PATENT ANALYSIS 130

PATENTS BY YEAR 130
TABLE 72 NUMBER OF U.S. PATENTS BY YEAR, FROM 2008 TO 2012 130
FIGURE 54 NUMBER OF U.S. PATENTS BY YEAR, FROM 2008 TO 2012 131
PATENTS BY TYPE 131
TABLE 73 NUMBER OF U.S. PATENTS BY TYPE, FROM 2008-2012 131
FIGURE 55 NUMBER OF U.S. PATENTS BY TYPE, FROM 2008-2012 131
PATENTS BY COMPANY 132
TABLE 74 NUMBER OF U.S. PATENTS BY COMPANY, FROM 2008-OCTOBER 2012 133
PATENTS BY COUNTRY 134
TABLE 75 NUMBER OF U.S. PATENTS BY COUNTRY, FROM 2008-2012 134
PATENTS BY ASSIGNEE 134
TABLE 76 NUMBER OF U.S. PATENTS BY ASSIGNEE, FROM 2008-2012 135
FIGURE 56 NUMBER OF U.S. PATENTS BY ASSIGNEE, FROM 2008-2012 135

CHAPTER 11 CURRENT SITUATION 137

CHAPTER 12 COMPANY PROFILES 141

AGFA HEALTHCARE 141
AGILTRON INCORPORATED 141
BAYSPEC, INC. 141
BIOPTIGEN 142
CARL ZEISS MEDITEC 142
HEIDELBERG ENGINEERING 143
HELIOTIS AG 144
IMALUX CORPORATION 144
LIGHTLAB IMAGING 145
MICHELSON DIAGNOSTICS 145
NIDEK CO., LTD. 146
NOVACAM TECHNOLOGIES INC. 146
NINE POINT MEDICAL 147
OPTOS 147
OPTOVUE, INC. 148
OPTOPOL TECHNOLOGY S.A. 149
PHOENIX RESEARCH LABORATORIES, INC. 149
PandP OPTICA 149
SANTEC CORPORATION 150
SHENZHEN MOPTIM IMAGING TECHNIQUE CO. 150
TOMEY 151
TOMOPHASE CORPORATION 151
TOPCON MEDICAL SYSTEMS, INC. 152
TORNADO SPECTRAL SYSTEMS 152
THORLABS INC. 153

CHAPTER 13 APPENDIX I-ABBREVIATIONS 155



LIST OF TABLES

SUMMARY TABLE GLOBAL REVENUE OF OCT MARKET, THROUGH 2017 ($ MILLIONS) 8
TABLE 1 MAIN CHARACTERISTICS OF OCT 10
TABLE 2 USES OF OPTICAL COHERENCE TOMOGRAPHY 11
TABLE 3 ADVANTAGES AND DISADVANTAGES OF OPTICAL COHERENCE
TOMOGRAPHY 12
TABLE 4 APPLICATIONS OF OPTICAL COHERENCE TOMOGRAPHY 13
TABLE 5 HISTORICAL DEVELOPMENTS IN OPTICAL COHERENCE TOMOGRAPHY 14
TABLE 6 TYPE OF TECHNOLOGIES USED IN OPTICAL COHERENCE TOMOGRAPHY 15
TABLE 7 MODES OF IMPLEMENTATION IN OPTICAL COHERENCE TOMOGRAPHY 15
TABLE 8 COMPARISON OF DIFFERENT OCT TECHNOLOGY 19
TABLE 9 NEW OCT PRODUCTS APPROVED FROM 2008 TO 2012 24
TABLE 10 RECALLS AND SAFETY ALERTS FROM 2008 TO 2012 28
TABLE 11 NEW OCT INNOVATIONS FROM 2008 TO 2012 33
TABLE 12 PIPELINE PRODUCTS FOR THE OCT MARKET 36
TABLE 13 GLOBAL REVENUE OF OCT BY TYPE, THROUGH 2017 ($ MILLIONS) 41
TABLE 14 MARKET SHARES OF OCT BY TYPE, 2011 (%) 42
TABLE 15 GLOBAL REVENUE OF OCT BY REGION, THROUGH 2017 ($ MILLIONS) 45
TABLE 16 GLOBAL MARKET SHARE OF OCT BY REGION, 2011 (%) 46
TABLE 17 GLOBAL REVENUE OF TD-OCT AND PS-OCT BY REGION, THROUGH 2017 ($
MILLIONS) 47
TABLE 18 MARKET SHARE OF GLOBAL REVENUE OF TD-OCT AND PS-OCT BY REGION,
2011 (%) 48
TABLE 19 GLOBAL REVENUE OF FD-OCT AND TIME-ENCODED OCT BY REGION,
THROUGH 2017 ($ MILLIONS) 49
TABLE 20 MARKET SHARE OF FD-OCT AND TIME-ENCODED OCT BY REGION, 2011
(%) 50
TABLE 21 GLOBAL REVENUE OF FF-OCT AND OD-OCT BY REGION, THROUGH 2017 ($
MILLIONS) 51
TABLE 22 MARKET SHARE OF FF-OCT AND OD-OCT BY REGION, 2011 (%) 52
TABLE 23 GLOBAL MARKET OF OCT BY END USERS, THROUGH 2017 ($ MILLIONS) 60
TABLE 24 GLOBAL MARKET SHARE OF OCT BY END USERS, 2011 (%) 61
TABLE 25 GLOBAL REVENUE OF TD-OCT AND PS-OCT, THROUGH 2017 ($ MILLIONS) 64
TABLE 26 MARKET SHARE OF TD-OCT AND PS-OCT BY TYPE, 2011 (%) 65
TABLE 27 GLOBAL REVENUE OF TD-OCT BY REGION, THROUGH 2017 ($ MILLIONS) 68
TABLE 28 GLOBAL REVENUE OF PS-OCT BY REGION, THROUGH 2017 ($ MILLIONS) 68
TABLE 29 MARKET SHARE OF PS-OCT BY REGION, 2011 (%) 70
TABLE 30 GLOBAL REVENUE OF PS-OCT AND TD-OCT BY END USERS, THROUGH
2017 ($ MILLIONS) 70
TABLE 31 GLOBAL EXPENDITURE OF TD-OCT AND PS-OCT IN THE PHARMACEUTICAL
AND BIOTECHNOLOGY INDUSTRIES, THROUGH 2017 ($ MILLIONS) 73
TABLE 32 GLOBAL EXPENDITURE OF TD-OCT AND PS-OCT IN THE ENVIRONMENTAL
SCIENCES INDUSTRY, THROUGH 2017 ($ MILLIONS) 75
TABLE 33 GLOBAL EXPENDITURE OF TD-OCT AND PS-OCT IN THE FOOD AND
BEVERAGE INDUSTRY, THROUGH 2017 ($ MILLIONS) 76
TABLE 34 GLOBAL EXPENDITURE OF TD-OCT AND PS-OCT IN OTHER INDUSTRIES,
THROUGH 2017 ($ MILLIONS) 78
TABLE 35 MARKET SHARE OF TD-OCT AND PS-OCT BY APPLICATION, 2011 (%) 79
TABLE 36 MAJOR MANUFACTURERS IN TD-OCT, 2011 80
TABLE 37 MARKET SHARE FOR MANUFACTURERS IN TD-OCT, 2011 (%) 80
TABLE 38 MAJOR MANUFACTURERS IN PS-OCT, 2011 81
TABLE 39 MARKET SHARE FOR THE MANUFACTURERS IN PS-OCT, 2011 (%) 81
TABLE 40 GLOBAL REVENUE OF FD-OCT AND TIME-ENCODED OCT BY TYPE,
THROUGH 2017 ($ MILLIONS) 86
TABLE 41 MARKET SHARE OF FD-OCT AND TIME-ENCODED OCT, 2011 (%) 87
TABLE 42 GLOBAL REVENUE OF FD-OCT AND TIME-ENCODED OCT BY REGION,
THROUGH 2017 ($ MILLIONS) 89
TABLE 43 GLOBAL REVENUE OF FD-OCT BY REGION, THROUGH 2017 ($ MILLIONS) 90
TABLE 44 GLOBAL REVENUE OF TIME-ENCODED OCT BY REGION, THROUGH 2017 ($
MILLIONS) 91
TABLE 45 MARKET SHARES OF FD-OCT AND TIME-ENCODED OCT BY REGION, 2011
(%) 92
TABLE 46 GLOBAL REVENUE OF FD-OCT AND TIME-ENCODED OCT BY END USERS,
THROUGH 2017 ($ MILLIONS) 93
TABLE 47 GLOBAL REVENUE OF FD-OCT AND TIME-ENCODED DOMAIN OCT IN
CARDIOLOGY, THROUGH 2017 ($ MILLIONS) 95
TABLE 48 GLOBAL REVENUE OF FD-OCT AND TIME-ENCODED OCT IN
OPHTHALMOLOGY, THROUGH 2017 ($ MILLIONS) 97
TABLE 49 GLOBAL REVENUE OF FD-OCT AND TIME-ENCODED OCT IN ONCOLOGY,
THROUGH 2017 ($ MILLIONS) 98
TABLE 50 GLOBAL REVENUE OF FD-OCT AND TIME-ENCODED OCT IN OTHER
SECTORS, THROUGH 2017 ($ MILLIONS) 100
TABLE 51 MARKET SHARE OF FD-OCT AND TIME-ENCODED OCT, 2011 (%) 101
TABLE 52 MAJOR MANUFACTURERS IN FOURIER OR SPECTRAL DOMAIN OCT, 2011 102
TABLE 53 MARKET SHARE OF THE MANUFACTURERS IN FOURIER OR SPECTRAL
DOMAIN OCT, 2011 (%) 103
TABLE 54 MAJOR MANUFACTURERS IN TIME-ENCODED OCT OR SS-OCT, 2011 104
TABLE 55 MARKET SHARE OF THE MANUFACTURERS OF TIME-ENCODED OCT OR
SS-OCT, 2011 (%) 104
TABLE 56 GLOBAL REVENUE OF FF-OCT AND OD-OCT, THROUGH 2017 ($ MILLIONS) 109
TABLE 57 MARKET SHARE OF FF-OCT AND OD-OCT BY TYPE, 2011 (%) 110
TABLE 58 GLOBAL REVENUE OF FF-OCT AND OD-OCT BY REGION, THROUGH 2017 ($
MILLIONS) 112
TABLE 59 GLOBAL REVENUE OF FF-OCT BY REGION, THROUGH 2017 ($ MILLIONS) 113
TABLE 60 GLOBAL REVENUE OF OD-OCT BY REGION, THROUGH 2017 ($ MILLIONS) 114
TABLE 61 MARKET SHARE OF FF-OCT AND OD-OCT BY REGION, 2011 (%) 115
TABLE 62 GLOBAL REVENUE OF FF-OCT AND OD-OCT BY END USERS, THROUGH
2017 ($ MILLIONS) 117
TABLE 63 GLOBAL REVENUE OF FF-OCT AND OD-OCT IN ENDOSCOPY, THROUGH
2017 ($ MILLIONS) 119
TABLE 64 GLOBAL REVENUE OF FF-OCT AND OD-OCT IN ONCOLOGY, THROUGH
2017 ($ MILLIONS) 120
TABLE 65 GLOBAL EXPENDITURE OF FF-OCT AND OD-OCT IN INTERSTITIAL CELL
STUDIES, THROUGH 2017 ($ MILLIONS) 122
TABLE 66 GLOBAL EXPENDITURE OF FF-OCT AND OD-OCT IN OTHER CATEGORIES,
THROUGH 2017 ($ MILLIONS) 124
TABLE 67 MARKET SHARE OF FF-OCT AND OD-OCT BY END USERS, 2011 (%) 125
TABLE 68 MAJOR MANUFACTURERS IN FF-OCT, 2011 126
TABLE 69 MARKET SHARE FOR MANUFACTURERS IN FF-OCT, 2011 (%) 127
TABLE 70 MAJOR MANUFACTURERS IN OD-OCT, 2011 128
TABLE 71 MARKET SHARE FOR MANUFACTURERS IN OD-OCT, 2011 (%) 128
TABLE 72 NUMBER OF U.S. PATENTS BY YEAR, FROM 2008 TO 2012 130
TABLE 73 NUMBER OF U.S. PATENTS BY TYPE, FROM 2008-2012 131
TABLE 74 NUMBER OF U.S. PATENTS BY COMPANY, FROM 2008-OCTOBER 2012 133
TABLE 75 NUMBER OF U.S. PATENTS BY COUNTRY, FROM 2008-2012 134
TABLE 76 NUMBER OF U.S. PATENTS BY ASSIGNEE, FROM 2008-2012 135



LIST OF FIGURES

SUMMARY FIGURE GLOBAL REVENUE OF OCT MARKET, 2010-2017 ($ MILLIONS) 8
FIGURE 1 GLOBAL REVENUE OF OCT BY TYPE, 2010-2017 ($ MILLIONS) 41
FIGURE 2 MARKET SHARES OF OCT BY TYPE, 2011 (%) 42
FIGURE 3 GLOBAL REVENUE OF OCT BY REGION, 2010-2017 ($ MILLIONS) 45
FIGURE 4 GLOBAL MARKET SHARE OF OCT BY REGION, 2011 (%) 46
FIGURE 5 GLOBAL REVENUE OF TD-OCT AND PS-OCT BY REGION, 2010-2017 ($
MILLIONS) 47
FIGURE 6 MARKET SHARE OF GLOBAL REVENUE OF TD-OCT AND PS-OCT BY REGION,
2011 (%) 48
FIGURE 7 GLOBAL REVENUE OF FD-OCT AND TIME-ENCODED OCT BY REGION,
2010-2017 ($ MILLIONS) 49
FIGURE 8 MARKET SHARE OF FD-OCT AND TIME-ENCODED OCT BY REGION, 2011 (%) 50
FIGURE 9 GLOBAL REVENUE OF FF-OCT AND OD-OCT BY REGION, 2010-2017 ($
MILLIONS) 51
FIGURE 10 MARKET SHARE OF FF-OCT AND OD-OCT BY REGION, 2011 (%) 52
FIGURE 11 GLOBAL MARKET OF OCT BY END USERS, 2010-2017 ($ MILLIONS) 60
FIGURE 12 GLOBAL MARKET SHARE OF OCT BY END USERS, 2011 (%) 61
FIGURE 13 GLOBAL REVENUE OF TD-OCT AND PS-OCT, 2010-2017 ($ MILLIONS) 64
FIGURE 14 MARKET SHARE OF TD-OCT AND PS-OCT BY TYPE, 2011 (%) 65
FIGURE 15 GLOBAL REVENUE OF TD-OCT BY REGION, 2010-2017 ($ MILLIONS) 68
FIGURE 16 GLOBAL REVENUE OF PS-OCT BY REGION, 2010-2017 ($ MILLIONS) 69
FIGURE 17 MARKET SHARE OF PS-OCT BY REGION, 2011 (%) 70
FIGURE 18 GLOBAL REVENUE OF PS-OCT AND TD-OCT BY END USERS, 2010-2017 ($
MILLIONS) 72
FIGURE 19 GLOBAL EXPENDITURE OF TD-OCT AND PS-OCT IN THE
PHARMACEUTICAL AND BIOTECHNOLOGY INDUSTRIES, 2010-2017 ($ MILLIONS) 73
FIGURE 20 GLOBAL EXPENDITURE OF TD-OCT AND PS-OCT IN THE ENVIRONMENTAL
SCIENCES INDUSTRY, 2010-2017 ($ MILLIONS) 75
FIGURE 21 GLOBAL EXPENDITURE OF TD-OCT AND PS-OCT IN THE FOOD AND
BEVERAGE INDUSTRY, 2010-2017 ($ MILLIONS) 77
FIGURE 22 GLOBAL EXPENDITURE OF TD-OCT AND PS-OCT IN OTHER INDUSTRIES,
2010-2017 ($ MILLIONS) 78
FIGURE 23 MARKET SHARE OF TD-OCT AND PS-OCT BY APPLICATION, 2011 (%) 79
FIGURE 24 MARKET SHARE FOR MANUFACTURERS IN TD-OCT, 2011 (%) 80
FIGURE 25 MARKET SHARE FOR THE MANUFACTURERS IN PS-OCT, 2011 (%) 81
FIGURE 26 GLOBAL REVENUE OF FD-OCT AND TIME-ENCODED OCT BY TYPE,
2010-2017 ($ MILLIONS) 86
FIGURE 27 MARKET SHARE OF FD-OCT AND TIME-ENCODED OCT, 2011 (%) 87
FIGURE 28 GLOBAL REVENUE OF FD-OCT AND TIME-ENCODED OCT BY REGION,
2010-2017 ($ MILLIONS) 89
FIGURE 29 GLOBAL REVENUE OF FD-OCT BY REGION, 2010-2017 ($ MILLIONS) 90
FIGURE 30 GLOBAL REVENUE OF TIME-ENCODED OCT BY REGION, 2010-2017 ($
MILLIONS) 91
FIGURE 31 MARKET SHARES OF FD-OCT AND TIME-ENCODED OCT BY REGION, 2011
(%) 92
FIGURE 32 GLOBAL REVENUE OF FD-OCT AND TIME-ENCODED OCT BY END USERS,
2010-2017 ($ MILLIONS) 93
FIGURE 33 GLOBAL REVENUE OF FD-OCT AND TIME-ENCODED DOMAIN OCT IN
CARDIOLOGY, 2010-2017 ($ MILLIONS) 95
FIGURE 34 GLOBAL REVENUE OF FD-OCT AND TIME-ENCODED OCT IN
OPHTHALMOLOGY, 2010-2017 ($ MILLIONS) 97
FIGURE 35 GLOBAL REVENUE OF FD-OCT AND TIME-ENCODED OCT IN ONCOLOGY,
2010-2017 ($ MILLIONS) 99
FIGURE 36 GLOBAL REVENUE OF FD-OCT AND TIME-ENCODED OCT IN OTHER
SECTORS, 2010-2017 ($ MILLIONS) 101
FIGURE 37 MARKET SHARE OF FD-OCT AND TIME-ENCODED OCT, 2011 (%) 101
FIGURE 38 MARKET SHARE OF THE MANUFACTURERS IN FOURIER OR SPECTRAL
DOMAIN OCT, 2011 (%) 103
FIGURE 39 MARKET SHARE OF THE MANUFACTURERS OF TIME-ENCODED OCT OR
SS-OCT, 2011 (%) 104
FIGURE 40 GLOBAL REVENUE OF FF-OCT AND OD-OCT, 2010-2017 ($ MILLIONS) 109
FIGURE 41 MARKET SHARE OF FF-OCT AND OD-OCT BY TYPE, 2011 (%) 110
FIGURE 42 GLOBAL REVENUE OF FF-OCT AND OD-OCT BY REGION, 2010-2017 ($
MILLIONS) 113
FIGURE 43 GLOBAL REVENUE OF FF-OCT BY REGION, THROUGH 2017 ($ MILLIONS) 114
FIGURE 44 GLOBAL REVENUE OF OD-OCT BY REGION, 2010-2017 ($ MILLIONS) 114
FIGURE 45 MARKET SHARE OF FF-OCT AND OD-OCT BY REGION, 2011 (%) 115
FIGURE 46 GLOBAL REVENUE OF FF-OCT AND OD-OCT BY END USERS, 2010-2017 ($
MILLIONS) 117
FIGURE 47 GLOBAL REVENUE OF FF-OCT AND OD-OCT IN ENDOSCOPY, 2010-2017
($ MILLIONS) 119
FIGURE 48 GLOBAL REVIEW OF FF-OCT AND OD-OCT IN ONCOLOGY, 2010-2017 ($
MILLIONS) 121
FIGURE 49 GLOBAL EXPENDITURE OF FF-OCT AND OD-OCT IN INTERSTITIAL CELL
STUDIES, 2010-2017 ($ MILLIONS) 123
FIGURE 50 GLOBAL EXPENDITURE OF FF-OCT AND OD-OCT IN OTHER CATEGORIES,
2010-2017 ($ MILLIONS) 125
FIGURE 51 MARKET SHARE OF FF-OCT AND OD-OCT BY END USERS, 2011 (%) 125
FIGURE 52 MARKET SHARE FOR MANUFACTURERS IN FF-OCT, 2011 (%) 127
FIGURE 53 MARKET SHARE FOR MANUFACTURERS IN OD-OCT, 2011 (%) 128
FIGURE 54 NUMBER OF U.S. PATENTS BY YEAR, FROM 2008 TO 2012 131
FIGURE 55 NUMBER OF U.S. PATENTS BY TYPE, FROM 2008-2012 131
FIGURE 56 NUMBER OF U.S. PATENTS BY ASSIGNEE, FROM 2008-2012 135

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