This Kalorama Information report - The World Market for Cancer Therapeutics and Biotherapeutics, 4th Edition - focuses on several segments for cancer treatment including:

  • Chemotherapy, including-subcategories Alkylating Agents, Antimetabolites, Cytotoxic Agents, Plant Derivatives -Brands such as Elotaxin, Taxotere, Gemzar, Alimta and Temodar with Market Share for each

  • Hormone Therapy: -Subcategories include Corticosteroids, Hormone Agonists/Antagonists, Aromatase Inhibitors and SERMS-Brands such as Arimidex, Casodex, Zoladex, Femara and Lupron with Market Share for each.

  • Immunotherapy and Biotherapy, including: -Monoclonal antibodies, interleukins/interferons, vaccines and other biotherapy-Brands such as Rituxan, Herceptin, Gleevec, Evastin and Erbitux


One of the most promising new approaches in modern cancer treatment is immunotherapy or biotherapy, the development of methods to augment and enhance the body’s natural tendency to defend itself against malignant tumors without damaging healthy tissue. The report devotes particular attention to these new therapies.

This report, Kalorama's fourth complete research effort into the oncology treatments market in the past ten years, provides market size information for the various types of cancers including the following:



  • Bladder

  • Breast

  • Cervical

  • Colorectal

  • Esophageal

  • Head/Neck

  • Kidney

  • Leukemia

  • Liver

  • Lung

  • Lymphoma

  • Melanoma

  • Multiple Myeloma

  • Neuroblastoma

  • Ovarian

  • Pancreatic

  • Prostate

  • Stomach


Table Of Contents

CHAPTER ONE: EXECUTIVE SUMMARY

Introduction

Scope and Methodology

Size and Growth of the Market

Issues and Trends Affecting Market

Leading Competitors

CHAPTER TWO: INTRODUCTION

What is Cancer

Biochemistry of Cancer Cells

Carcinogen Metabolism

Causes of Cancer Growth

Environmental Factors, DNA, RNA

Cellular Oncogenes

Tumor Suppressor Genes

History and Growth of the Cancer Treatment Market

Industry Structure

Product Segments and Technology

Chemotherapy: At a Glance

Hormone Therapy: At A Glance

Biotherapy: At A Glance

Radiation Therapy: At a Glance

Demographics and Statistics

Global Cancer Statistics

Demographics

Aging Population

Life Expectancy and Cancer

Life Expectancy

Birth Rates

Description of Cancers

Bladder Cancer

Brain Cancer

Glioblastoma

Neuroblastoma

Breast Cancer

Cervical Cancer

Colorectal Cancer

Esophageal Cancer

Head and Neck

Kidney

Leukemia

Liver

Lung Cancer

Lymphoma

Melanoma

Multiple Myeloma

Ovarian Cancer

Pancreas

Prostate Cancer

Stomach Cancer

CHAPTER THREE: CHEMOTHERAPY

Overview

Product Descriptions and Examples

Alkylating Agents

Antimetabolites

Cytotoxic Agents

Plant Derivatives

Market Size and Growth

Markets by Product Type

Markets by Geographical Segments

U.S. Market

European Market

Japan Market

ROW Market

Market Data by Indication

Competitive Analysis

CHAPTER FOUR: HORMONE THERAPY

Overview

Product Descriptions and Examples

Corticosteroids

Hormone Agonists and Antagonists

Aromatase Inhibitors

Selective Estrogen Receptor Modulators (SERMs)

Market Size and Growth

Markets by Product Type

Markets by Geographical Segments

U.S. Market

Europe Market

Japan Market

ROW Market

Market Data by Indication

Competitive Analysis

CHAPTER FIVE: BIOTHERAPEUTICS

Overview

Product Descriptions and Examples

Monoclonal Antibodies

Interleukins/Interferons

Tyrisoine Kinase Inhibitors

Other Biotherapeutics

Radioimmunotherapy

Market Size and Growth

Markets by Product Type

Markets by Geographical Segments

U.S. Market

Europe Market

Japan Market

ROW Market

Market Data by Indication

Competitive Analysis

CHAPTER SIX: WORLD CANCER THERAPIES: TOTAL MARKET SIZE AND FORECAST

Overview

Total Market Size and Forecast

Geographical Market Distribution

Competitive Landscape

CHAPTER SEVEN: ISSUES AND TRENDS AFFECTING THE CANCER MARKET

Introduction

Insurance and Reimbursement Issues

Cancer Drug Costs

Personalized Medicine

Targeted Cancer Therapy

Pharmacogenomics

Alliances, Acquisitions and Licensing Agreements

Patient-Reported Outcomes

Alcohol’s Affect on Cancer Incidence

Healthy Lifestyles Continue to Show Promise for Cancer Prevention

Obesity in the U.S.

U.S. Obesity Rates Differ Among Ethnic Groups

Outlook for a Healthier U.S. Population

Cancer Trends

Marketing and Distribution Trends

Geographical Trends

United States

Europe

Japan

Elderly Clinical Trial Involvement

Late-Stage Drug Development Trends

Significant Developments

Alpharadin

Afatinib

Axitinib

Bosutinib

Brentuximab

Carfilzomib

Crizotinib

Erwinaze

Exelbine

Motesanib

Omnitarg

Regorafenib

Ridaforolimus

Zaltrap

Recent NDA Activity

New Approvals

CHAPTER EIGHT: CORPORATE PROFILES

Introduction

AstraZeneca plc

Bristol-Myers Squibb Company

Eli Lilly and Company

Johnson and Johnson

Merck and Company, Inc.

Novartis AG

Pfizer, Inc.

Roche

Sanofi

APPENDIX: MAJOR COMPETITORS’ ADDRESSES




LIST OF EXHIBITS

CHAPTER ONE: EXECUTIVE SUMMARY

Table 1-1: World Cancer Market by Product Type (Chemotherapy, Hormone Therapy, Biotherapeutics), 2005-2015

Figure 1-1: World Cancer Market, Market by Product Type (Chemotherapy, Hormone Therapy, Biotherapeutics), 2005-2015

Figure 1-2: World Cancer Market, Market Share by Product Type, 2010

CHAPTER TWO: INTRODUCTION

Table 2-1: Viruses Associated with Cancer in Humans

Figure 2-1: Approved Cancer Therapies in the United States by Primary Indication

Table 2-2: World Cancer Incidence by Selected Types of Cancer, 2010 and 2020, (Lung,Breast, Colon/ Rectum, Stomach, Liver, Prostate, Cervical, Ovarian, Lymphoma, Pancreatic, Melanoma)

Figure 2-2: Estimated and Projected World Cancer Incidence by Selected Types of Cancer, 2010 and 2020

Table 2-3: Total Cancer Incidence by Sex and Country (Canada, China, France, Germany, India, Italy, Brazil, Russia, Japan, Spain United Kingdom, United States), 2010 Estimates

Figure 2-3: Total Cancer Incidence by Sex and Country(Canada, China, France, Germany, India, Italy, Brazil, Russia, Japan, Spain United Kingdom, United States), 2010 Estimates

Table 2-4: World Population by Selected Geographical Region (Africa, Asia, Europe, North America, Oceania, South America, World), 2010 - 2050

Figure 2-4: World Population by Selected Geographical Region (Africa, Asia, Europe, North America, Oceania, South America, World), 2010-2050

Table 2-5: Percent Population Over 65 by Year and Region, 2010-2050

Figure 2-5: Estimated World Population by Age, 2010 and 2050

Table 2-6: Average Life Expectancy in Years by Country 1980, 2004 and 2009

Figure 2-6: Average Life Expectancy in Years by Country 1980 and 2009

Figure 2-7: United States Average Years of Life Lost Per Person Dying of

Cancer, All Races, Both Sexes, 2006

Figure 2-8: United States Estimated Person-Years of Life Lost Due to Cancer, All Races, Both Sexes, 2006

Table 2-7: Crude Birth Rate per 1,000 Persons 2000, 2005 and 2010

Figure 2-9: Crude Birth Rate per 1,000 Persons 2000, 2005 and 2010

Table 2-9: Types of Leukemia

Table 2-9: Types of Primary Lung Cancer

Table 2-10: Classification of Non-Hodgkin’s Lymphomas

Table 2-11: Malignant Conditions of the Skin

CHAPTER THREE: CHEMOTHERAPY

Table 3-1: Leading Products, 2010

Table 3-2: World Chemotherapy Market, 2005-2015

Figure 3-1: World Chemotherapy Market, 2005-2015

Table 3-3: World Chemotherapy Market, Sales by Drug Classification, (Alkylating Agents, Antimetabolites, Cytotoxic agents, Plant Derivatives) 2010

Figure 3-2: World Chemotherapy Market by Drug Classification, (Alkylating Agents, Antimetabolites, Cytotoxic agents, Plant Derivatives)

Table 3-4: World Chemotherapy Market, Sales by Drug Classification (Alkylating Agents, Antimetabolites, Cytotoxic agents, Plant Derivatives), Estimated 2015

Figure 3-3: World Chemotherapy Market by Drug Classification (Alkylating Agents, Antimetabolites, Cytotoxic agents, Plant Derivatives), Estimated 2015

Figure 3-4: World Chemotherapy Current Market by Region (US, EU, Japan, ROW)

Figure 3-5: World Chemotherapy Market by Region 2015 (US, EU, Japan, ROW)

Table 3-5: World Chemotherapy Market Type by Cancer Type (Lung, Breast, Colon, Brain, Ovarian, Other Total)

Figure 3-6: World Chemotherapy Market by Cancer Type (Lung, Breast, Colon, Brain, Ovarian, Other Total)

Table 3-6: World Chemotherapy Market, Leading Suppliers Shares, 2010

Figure 3-7: World Chemotherapy Market, Leading Suppliers Shares, 2010

CHAPTER FOUR: HORMONE THERAPY

Table 4-1: Leading Products, 2010

Table 4-2: World Hormone Therapy Market, 2005-2015

Figure 4-1: World Hormone Therapy Market, 2005-2015

Table 4-3: World Hormone Therapy Market, Sales by Drug Classification (Corticosteroids, Hormone agonists/ Antagonists, Aromatase Inhibitors, SERMs), 2010

Figure 4-2: World Hormone Therapy Market, Market by Drug Classification (Corticosteroids, Hormone agonists/ antagonists, Aromatase inhibitors, SERMs) and Percent Market Share, 2010

Table 4-4: World Hormone Therapy Market, Sales by Drug Classification (Corticosteroids, Hormone agonists/ antagonists, Aromatase inhibitors , SERMs), Estimated 2015

Figure 4-3: World Hormone Therapy Market, Market by Drug Classification (Corticosteroids, Hormone agonists/ antagonists, Aromatase inhibitors, SERMs) and Percent Market Share, 2015

Figure 4-4: World Hormone Therapy Current Market by Region (US, EU, Japan, ROW)

Figure 4-5: World Hormone Therapy Market by Region 2015 (US, EU, Japan, ROW)

Table 4-5: World Hormone Therapy Market by Cancer Type (Breast, Prostate, Other)

Figure 4-6: World Hormone Therapy Market by Cancer Type (Breast, Prostate, Other)

Table 4-6: World Hormone Therapy Market, Leading Suppliers Shares by Market Revenues, 2010

Figure 4-7: World Hormone Therapy Market, Leading Suppliers Market Share, 2010

CHAPTER FIVE: BIOTHERAPEUTICS

Table 5-1: Leading Biopharmaceutical Cancer Treatment Products (Brand Name, Generic Name, Manufacturer/ Marketer, Common Uses, Annual Sales ), 2010

Table 5-2: World Cancer Biotherapeutics Market, 2005-2015

Figure 5-1: World Cancer Biotherapeutics Market, 2005-2015

Table 5-3: World Biotherapeutics Market, Sales by Drug Classification (Monoclonal Antibodies, Interleukins/Interferons, Tyrosine Kinase Inhibitors, Other Biotherapeutics), 2010

Figure 5-2: World Biotherapeutics Market by Drug Classification (Monoclonal Antibodies, Interleukins/Interferons, Tyrosine Kinase Inhibitors, Other Biotherapeutics)

Table 5-4: World Biotherapeutics Market, Drug Classification (Monoclonal Antibodies, Interleukins/Interferons, Tyrosine Kinase Inhibitors, Other Biotherapeutics), 2015

Figure 5-3: World Biotherapeutics Market by Drug Classification (Monoclonal Antibodies, Interleukins/Interferons, Tyrosine Kinase Inhibitors, Other Biotherapeutics), Estimated 2015

Figure 5-4: Cancer Biotherapeutics Market by Region (US, EU, Japan, ROW)

Figure 5-5: Cancer Biotherapeutics Market by Region (US, EU, Japan, ROW), 2015

Table 5-5: World Cancer Biotherapeutics Market by Cancer Type (Colon, Breast, Lymphoma, Leukemia, Others)

Figure 5-6: World Cancer Biotherapeutics Market by Cancer Type(Colon, Breast, Lymphoma, Leukemia, Others)

Table 5-6: World Biotherapeutics Market, Leading Suppliers Shares by Market Revenues, 2010

Figure 5-7: World Cancer Biotherapeutics Market, Leading Suppliers Market Share, 2010

CHAPTER SIX: WORLD CANCER THERAPIES: TOTAL MARKET SIZE AND FORECAST

Table 6-1: World Cancer Market, Market by Product Type, 2005-2015

Figure 6-1: World Cancer Market, Market by Product Type Revenues, 2005-2015

Figure 6-2: World Cancer Market, Market by Product Type and Percent Market Share, 2010

Figure 6-3: World Cancer Market, Market by Product Type and Percent Market Share, 2015

Table 6-2: World Cancer Market, Leading Suppliers’ Shares by Market Revenues, 2010

Figure 6-5: World Cancer Market, Leading Suppliers’ Market Share, 2010

CHAPTER SEVEN: ISSUES AND TRENDS AFFECTING THE CANCER MARKET

Table 7-1: Obesity Rates by U.S. State, 2009

Table 7-2: Select Products in Development by Development Phase

Figure 7-1: Late Stage Cancer Compounds in Development for Major Indications, Distribution Estimates

Table 7-3: Recent NDA Activity: January 2011-July 2011

Table 7-4: Select New Approvals (NCE, Indications, Dosage, Formulations) ,2010-11

CHAPTER EIGHT: CORPORATE PROFILES

Figure 8-1: Late stage Cancer Therapies in Development for Leading Companies

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