Global Spinal Surgery Industry

• Publication date: October 2011

This report analyzes the worldwide markets for Spinal Surgery in US$ Million by the following Product Segments: Spinal Fusion Devices, Spinal Fixation Devices, Artificial Discs, and Vertebral Compression Fracture Devices. The report provides separate comprehensive analytics for the US, Europe, Asia-Pacific and Rest of World. Annual estimates and forecasts are provided for the period 2008 through 2017. The report profiles 92 companies including ...

This report analyzes the worldwide markets for Spinal Surgery in US$ Million by the following Product Segments: Spinal Fusion Devices, Spinal Fixation Devices, Artificial Discs, and Vertebral Compression Fracture Devices. The report provides separate comprehensive analytics for the US, Europe, Asia-Pacific and Rest of World. Annual estimates and forecasts are provided for the period 2008 through 2017. The report profiles 92 companies including many key and niche players such as Alphatec Spine Inc., Altiva Corporation Inc., ArthroCare Corporation, Biomet, Inc., Depuy Spine Inc., Medtronic Inc., Medtronic Sofamor Danek, Inc., Kyphon, Inc., NuVasive Inc.,. Orthofix International N.V., Orthovita Inc., SCIENT'X SA, Smith & Nephew Plc, SpineVision, Stryker Corporation, Synthes Inc., and Zimmer Spine Inc. Market data and analytics are derived from primary and secondary research. Company profiles are mostly extracted from URL research and reported select online sources.

Global Orthopedic Industry

1. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS 1
Study Reliability and Reporting Limitations 1
Disclaimers 2
Data Interpretation & Reporting Level 3
Quantitative Techniques & Analytics 3
Product Definitions and Scope of Study 3
Spinal Surgery 3
Spinal Fusion Devices 3
Spinal Fixation Devices 3
Artificial Discs 4
Vertebral Compression Fracture Devices 4

2. INDUSTRY OVERVIEW 5
Regional Perspective 5
Product Segment Perspective 5
Aging Population Drives Demand 5
Table 1: Select Musculoskeletal Conditions - Percentage
Breakdown by Age Group (includes corresponding Graph/Chart) 6
Table 2: World Demographic Trends: 65+ Group as a Percentage
of Total Population by Geographic Region - US, Canada,
Europe, Japan, Asia-Pacific, and Latin America for Years
2000, 2008, 2010, and 2020 (includes corresponding
Graph/Chart) 7
Spinal Surgery Market: Primary Growth Drivers 7
Spinal Surgery: The Last Resort 8
Risks Associated with Spinal Surgery: 8
Spinal Surgery Alternatives 8
Spinal Decompression with a ‘Herniated Disc Device 9
Pain Relief Medications 9

3. MARKET DYNAMICS 10
Spinal Fusion Devices Taking Back Seat 10
Innovations to Sustain Growth in Fusion Process 10
Artificial Disc Replacement: An Ideal Alternative to Spinal
Fusion 10
Minimally Invasive Procedures Gain Prominence 10
MIS Spinal Fusion - Another Prospective Avenue 11
Microscopic Surgeries-A Key Development 11
Growing Presence of Mid-Tier Firms & Start-Ups in Spinal Segment 11

4. COMPETITION 12
Table 3: Leading Players in the Global Spinal Surgery Market
(2010): Percentage Share Breakdown of Revenues for
Medtronic/Kyphon, DePuy, Synthes, Stryker, Zimmer, Biomet,
Orthofix, and Others (includes corresponding Graph/Chart) 12

Table 4: Leading Spinal Implant Manufacturers (2010):
Percentage Share Breakdown of Revenues for Medtronic, Johnson
and Johnson, Synthes, Stryker, and Others (includes
corresponding Graph/Chart) 13
Vertebral Compression Fracture 13
Disc Replacement Devices 13
Select Artificial Discs Available in the Market or in
Development, 2008 14
Review of Select Artificial Discs 14
Bryan Cervical Artificial Disc 14
Prestige Cervical Disc 14
Cervitech PCM Disc 14
Prodisc-C Artificial Cervical Disc 15
Cervicore Artificial Cervical Disc 15
Mobi-C Artificial Cervical Disc 15
SECURE-C Artificial Cervical Disc 15
Kineflex-C Artificial Cervical Disc 16
Consolidation Moves 16
Review of Select Recent Strategic Acquisitions 16

5. ANATOMY OF THE SPINE 17
Back Pain - A Warning Signal 17
What Causes Back Pain? 17
Herniated Disc 17
Degenerative Disc Disease 18
Osteophytes or Bone Spurs 18
Lumbar Spinal Stenosis 18
Osteroprosis 18
Osteoarthritis 18
Cervical Spondylosis 18
Scoliosis 19
Strains and Sprains 19
Compression Fractures 19
Vertebral Fractures 19
Precise Cause of Pain: Still Untraceable 19
Cervical Spine Disorders 19
Disc Herniation 19
Spinal Stenosis 19
Congenital Spine Disorders 19
Kyphosis 19
Lordosis 20
Scheuermann’s Kyphosis 20
Infectious and Inflammatory Diseases of Spine 20
Discitis 20
Sacroiliitis 20
Arachnoiditis 20
Mechanical Spine Disorders 20
Myelopathy 20
Radiculopathy 20
Spondylolysis 20
Spondylolisthesis 20

6. SPINAL SURGERY - AN INSIGHT 21
Spinal Surgery 21
Lumbar Spine Surgery 21
Cervical Spine Surgery 21
Minimally invasive Spinal Surgeries 22
Recuperation After Surgery 23
Novel Innovations Aid in Reduced Pain and Faster Recovery 23
Factors Conducive to Faster Recovery 23
Classification of Spinal Surgery 23
Classification By Technology 23
Spinal Fusion 23
Solid Fusion 24
Factors Influencing Solid Fusion 24
Disadvantages of Spinal Fusion 24
Minimally Invasive Spine Fusion: An Overview 25
Minimally Invasive Frontal Approach 25
Approach to Interbody Fusion Surgery 26
Posterior Lumbar Interbody Fusion (PLIF) 26
Anterior Lumbar Interbody Fusion (ALIF or TLIF or from the
front) 26
Non-fusion/Motion Preservation Technologies 26
Total Disc Replacement (TDR) 27
Nucleus Arthroplasty Motion Preservation System 27
Select Companies with Nucleus Arthroplasty Devices Under
Development 28
Dynamic Stabilization 28
Facet Joint Replacement 29

7. A BACKDROP OF SELECT PRODUCTS AND DEVICES INVOLVED 30
Spinal Fusion Devices 30
Spinal Fixation Devices 30
Artificial Discs 30
Vertebral Compression Fracture Devices 30
Other Devices and Materials 31
Bone Grafts 31
Bone Graft Substitutes and Enhancers 32
Demineralized Bone matrix (DBM) 32
Platelet-derived Growth Factors 32
Bone Morphogenetic Proteins (BMPs) 32

8. REVIEW OF SELECT SPINAL SURGERY AND TREATMENT PROCEDURES 33
Vertebroplasty 33
Kyphoplasty 33
Intradiscal Electrothermal Annuloplasty (IDET) 34
Endoscopic Spine Surgery 34
Percutaneous Discectomy 34
Foraminotomy 35
Laminectomy 35
Facet Thermal Ablation 36
Disc Decompression 36
Video-assisted thoracic surgery (VATS) 37
Gene Therapy 37
Table 5: Global Spinal Surgery Market (2010): Percentage
Share Breakdown of Surgical Procedures - Spine Fusion, Bone
Graft Substitutes, Disc Replacements, Image Guided Surgery,
Vertebroplasty/Kyphoplasty, Nucleus Replacements, and Others
(includes corresponding Graph/Chart) 38

9. PRODUCT DEVELOPMENT / APPROVAL/ LAUNCHES 39
Medtronic Unveils CD HORIZON® 39
Medtronic Introduces CD Horizon® Solera™ 39
Exactech Launches Proliant™ Polyaxial Pedicle Screw System 39
DePuy Spine Introduces VIPER® 3D MIS Correction Set 40
Medtronic Receives FDA Clearance for TSRH® Spinal System 40
K2M Receives FDA Approval for EVEREST™ Degenerative Spinal
System 40
Medyssey Spine Receives FDA Approval for LP Cage™ 40
Lanx Introduces Durango 41
Zimmer Launches UniWallis™ System 41
CareFusion Unveils New Vertebral Balloon 41
Covidien Obtains FDA Approval for DuraSeal™ Exact Spine Sealant 41
Integra LifeSciences Receive Approvals from FDA for Three
Spinal Fixation Devices 42
Zyga Technology Receives FDA Clearance for SImmetry
Sacroiliac Joint Fusion System 42
Lanx Launches Epic Anterior Fixation Device 42
Zimmer Holdings Unveils PathFinder NXT™ 42
Lanx Introduces Concero™ Facet Screw System 43
Integra Develops Portfolio of Sophisticated Orthobiologics
for Spine Surgery 43
X-spine Systems Receives FDA Approval for X-spine Axle
Interspinous Fusion System 44
ArthroCare Obtains FDA Approval for Parallax Contour
Vertebral Augmentation Device 44
Medyssey Receives FDA Approval for Zenius Thoracolumbar
Spinal System 44
Wenzel Spine Receives FDA Approval for VariLift® Stand-Alone
Expandable Interbody Fusion System 44
Life Spine Obtains FDA Clearance for PRESIDIO™ Spinal Plating
System and DYNA-LINK® Spinal System 45
X-spine Receives FDA Approval for Spinal Facet Screw System 45
Alphatec Receives CE Mark for Spinal Treatment Systems 45
Life Spine Receives FDA Approval for FS3 Posterior MIS Screw
System 46
LDR Receives Approval for Marketing Easyspine® Posterior
Osteosynthesis System in Japan 46
Integra Introduces Atoll Occipital-Cervical-Thoracic System 46
Medtronic Launches SOVEREIGN™ Spinal System 47
Medtronic Rolls Out MASTERGRAFT® Strip 47
US Spine Unveils Javelin™ MIS Locking Facet System 47
K2M Unveils Two New Minimally Invasive Spine Surgery Solutions 48
Integra Introduces Coral™ Extended Tab Spinal Screw Series 48
Depuy Spine Rolls Out HEALOS® Fx Injectable Bone Graft
Replacement 48
Salient Surgical Technologies Introduces Aquamantys™ Epidural
Vein Sealer 49
Mikai Unveils Falena® Interspinous Decompression Device 49
X-spine Receives FDA Approval for Calix Spinal Implant System 49
FDA Approves Medtronic Sofamor’s Premarket Approval
Application for Bryan Cervical Disc 50
Pioneer Surgical Receives FDA Approval for IDE pivotal study
of NuBac Implant 50
Scient'x Introduces Novel Cage System 50
DePuy Spine Introduces EAGLE™ Plus and SWIFT™ Plus ACP Systems 51
Medtronic Rolls out Discyphor Direct™ Catheter System 51
US Spine Receives FDA Approval for Preference 2 Complex Spine
System 51
Scient’x Receives USFDA Approval for Isobar DUO™ Dynamic
Stabilization System 52
Osteotech Obtains USFDA Approval for Plexur M™ Biocomposite 52
Orthofix Receives FDA Approval for Firebird Spinal Fixation
Device 52
LDR Introduces verteBRIDGE™ Anchoring Technology 52
LDR Releases ROI-T TM 53
LDR Releases ROI-A™ 53
DePuy Spine Launches CONCORDE™ Bullet Vertebral Body Replacement 53
DePuy Spine Introduces the EXPEDIUM™ 4.5 Spine System 54
DePuy Spine Launches VIPER™2 Pedicle Screw Fixation System 54
DePuy Spine Introduces EXPEDIUM™ PEEK Rod System 54
DePuy Spine Unveils CONFIDENCE SPINAL CEMENT SYSTEM™ 55
DePuy Spine Introduces Latest Anterior Cervical Plating Systems 55
Alphatec Holdings Introduces DYNAMO Semi-Rigid Spinal System 56
Integra LifeSciences Introduces a Smaller Variant of the
Accell TBM® 56
Scient'x Introduces Tribeca™ Cage System 56
Princess Grace Releases Balloon Kyphoplasty 57
Health Canada Approves the use of FzioMed’s Oxiplex® Gel 57
Pioneer Surgical Launches Cross-Fuse™ Lateral Option System 57
Globus Introduces Niko Spacer System 57
X-spine Receives USFDA Approval for BUTREX Buttress Plating
System 57
K2M Launches Lumbar Spacer Systems 58
Medtronic Launches Image-Guided Spinal Surgery System 58
Synergetics Introduces Ultrasonic Aspirator for Spinal Surgeries 58
Integra LifeSciences Receives FDA Approval for Integra Mozaik™
Osteoconductive Scaffold 59
Medtronic Unveils CD Horizon® Longitude™ Multi-level
Percutaneous Fixation System 59
Spine Wave Receives FDA Approval for CapSure™ PS Spine System 59
Synthes Receives FDA Approval for ProDisc®-C 59
Synthes Receives FDA Approval for chronOS™ Strip 60
Theken Spine Develops Unique Spinal Pedicle Screw in
Collaboration with a Surgeon 60
DePuy Spine Launches VERTIGRAFT VG2 TLIF Allograft 60
DePuy Spine Launches EXPEDIUM™ SFX™ Cross Connector system 61
DePuy Spine Launches AEGIS Anterior Lumbar Plate System 61
DePuy Spine Launches EXPEDIUM 6.35 Screw and Rod System 61
Abbott Introduces Universal Clamp™ Spinal Fixation System 62
HydroCision Introduces New SpineJet XL® Fusion Instruments 62
Innovative Spinal Technologies Launches Paramount VBR System 62
Alphatec Holdings Launches New NOVEL-TL Spinal Spacer System 62
Biomet Orthopedics Introduces Two New Hip Stems 63
Alphatec Launches CONNECT II Cervical Structural Allograft Spacer 63
Pioneer Surgical Releases Quantum MIS Rodding System 64
Spinal Elements Rolls out Mercury™ Spinal System 64
K2M Introduces SERENGETI™ Minimally Invasive Retractor System 64
Theken Spine Secures FDA Approval for Two of its Products 65
Vertebration Receives FDA Approval for its Xycor™ Spinal Implant 65
Medtronic Launches PRESTIGE Artificial Disc 65
X-spine Secures Approval from the FDA to Market its Capless LI
™ Pedicle Screw System 65
Theken Spine to Introduce Two New Products 66
Imaging3 to Launch Dominion Real-Time 3D Imaging Device 66
US Surgical Receives USFDA Approval for Ray TFC 66
NuVasive Introduces New Spinal Surgery Devices 67
Medtronic Introduces Spine Stabilizing Rod 67
Globus Medical Launches XPand R 67
Innovative Spinal Technologies Launches Paramount Pedicle
Screw System 68
Medtronic Launches CD HORIZON SPIRETM 68
SpineVision Launches FlexPLUS 68
Abbott Introduces New Harmony Retractor Minimally Invasive
Access System 68
NuVasive Unveils Gradient Plus™ Anterior Cervical Plating System 69
Medtronic Introduces CD HORIZON® LEGACYTM 4.5 Spinal System 69
Medtronic Receives TGA Approval for Three Devices 70

10. RECENT INDUSTRY ACTIVITY 71
Stryker Takes Over Orthovita 71
DSM Biomedical Signs Licensing Agreement with FH ORTHOPEDICS 71
Integra LifeSciences Takes Over SeaSpine 71
Premia Spine Takes Over Impliant’s Assets 71
Misonix Enters into Distribution Agreement with Instrumentacion 72
Cardo Medical Takes Over Assets of Vertebron 72
Medtronic and Tissuemed Ink Collaboration Agreement 72
X-spine Systems Signs Licensing Agreement with Gamma Spine 73
Wenzel Spine Inks Global Distribution Agreement with
Orthopaedic & Spine Development 73
SpineSmith Signs Agreement with GenOsteo 73
Amedica Corporation Takes Over US Spine 73
Sparton Medical Colorado Acquires Assets of Delphi Medical
Systems 74
Alphatec Acquires Scient'x Groupe 74
Exactech Acquires Assets of VertiFlex 74
Integra LifeSciences Acquires Products of Innovative Spinal
Technologies 75
Alphatec Spine and International Spine Innovations Enter into
Agreement 75
NuVasive to Take Over Cervitech 75
Norman Noble Expands Production Facility 75
Osteotech Enters into Distribution Agreement with Harvest 76
Orthofix Purchases IP of an Advanced Spinal System from IIS 76
Integra LifeSciences Takes Over Theken 76
Exactech Acquires Altiva 77
Spineology Secures US$7.5 million for Expansion 77
Encore Medical Division Changes Name to DJO Surgical 77
Alphatec Spine Enters into Agreement with Stout Medical 77
Zimmer Takes over Abbott Spine 78
Scient’x Repurchases Isobar License from Alphatec Spine 78
Bonati Institute Starts New Spine Center in Chile 78
Mubadala Healthcare Enters into Agreement with the Wooridul
Spine Hospital 78
Interventional Spine and Dr. Rudolf Morgenstern Sign Agreement
for PNSS 79
VSCI Inks a Development and Supply Agreement with SpineView 79
NuVasive Acquires Osiris Therapeutics’ Osteocel Biologics
Business 79
Bonesupport Takes Over Ultrazonix 79
Biomet Merges with LVB Acquisition Merger Sub 80
Zimmer Holdings Acquires Endius 80
Cytovance Biologics Inks Agreement with Bone Biologics 80
Alphatec Inks Agreement with Scient'x 80
Kyphon Acquires St. Francis Medical Technologies 81
NuVasive Acquires Biologic Product Technology from Radius Medical 81
ReAble Therapeutics and DJO Complete Merger Transaction 81
Pioneer Surgical Takes Over Angstrom Medica 81
Integra LifeSciences Takes Over IsoTis 82
TriMas Takes Over DEW Technologies 82
Osteotech and Novation Sign Single Source Agreement 82
Medtronic Takes Over Kyphon 82
Biomet Sports Medicine and Marc Tec Enter into Licensing
Agreement 82
Synthes Acquires N Spine 83
Pioneer Surgical Takes Over Encelle 83
Integra LifeSciences to Take Over Physician Industries 83
TriMas Takes Over DEW Technologies 83
ASC Enters into an Agreement with PTG 84
Medtronic and Axon Systems Enter into Agreement 84
Sandvik Acquires JKB Medical Technologies 84
Alphatec Spine Acquires Exclusive Global License to Develop V
-Stent 84
Alphatec Spine Enters into Licensing Agreement with JGMG
Bengochea 85
Smith & Nephew and Teknimed Ink Distribution Agreement 85
Scient’x Opens Regional Office in Singapore 85
Medtronic and Shandong Weigao to Establish Joint Venture in China 86
DePuy Spine Inks Acquisition Agreement with Disc-O-Tech 86
Sandvik Acquires Medtronic's Medical Instrumentation Plant 86
Sandvik Takes Over Doncasters Medical Technologies 86
Kensey Nash Acquires MacroPore Biosurgery 87
Healthcor Associates Acquires Stake in Paradigm Spine 87
X-spine Receives Patent for Disk Augmentation System 87
Orthofix Acquires Blackstone Medical 88
NuVasive Receives IDE Approval for NeoDisc Clinical Trial 88
LDR Merges LDR Spine and LDR Medical to Form LDR Holding
Corporation 88
Orthofix International Enters into an Agreement with
UnitedHealthcare 89
Blackstone Medical and Regeneration Technologies Sign
Production Agreement 89
Kyphon Acquires Disc-O-Tech 89

11. FOCUS ON SELECT PLAYERS 90
Alphatec Spine Inc. (US) 90
ArthroCare Corporation (US) 90
Biomet, Inc. (US) 91
Depuy Spine Inc. (US) 91
Exactech Inc. (US) 91
Altiva Corporation Inc. (US) 92
Medtronic Inc. (US) 92
Medtronic Sofamor Danek, Inc. (US) 93
Kyphon, Inc. (US) 93
NuVasive Inc. (US) 93
Orthofix International N.V. (US) 93
Scient’x-Alphatec Spine (France) 94
Smith & Nephew Plc (UK) 94
SpineVision (France) 95
Stryker Corporation (US) 95
Orthovita Inc. (US) 95
Synthes Inc. (US) 96
Zimmer Spine Inc. (US) 96

12. GLOBAL MARKET PERSPECTIVE 98
Table 6: World Recent Past, Current & Future Market Analysis
for Spinal Surgery Devices by Geographic Region -US, Europe,
Asia-Pacific and Rest of World Independently Analyzed with
Annual Sales Figures in US$ million for Years 2008 through
2017 (includes corresponding Graph/Chart) 98

Table 7: World 10-Year Perspective for Spinal Surgery Devices
by Geographic Region - Percentage Breakdown of Dollar Sales
for US, Europe, Asia-Pacific and Rest of World Markets for
Years 2008, 2011 & 2017 (includes corresponding Graph/Chart) 99

Table 8: World Recent Past, Current & Future Market Analysis
for Spinal Fusion Devices by Geographic Region -US, Europe,
Asia-Pacific and Rest of World Independently Analyzed with
Annual Sales Figures in US$ million for Years 2008 through
2017 (includes corresponding Graph/Chart) 100

Table 9: World 10-Year Perspective for Spinal Fusion Devices
by Geographic Region - Percentage Breakdown of Dollar Sales
for US, Europe, Asia-Pacific and Rest of World Markets for
Years 2008, 2011 & 2017 (includes corresponding Graph/Chart) 101

Table 10: World Recent Past, Current & Future Market Analysis
for Spinal Fixation Devices by Geographic Region -US, Europe,
Asia-Pacific and Rest of World Independently Analyzed with
Annual Sales Figures in US$ million for Years 2008 through
2017 (includes corresponding Graph/Chart) 102

Table 11: World 10-Year Perspective for Spinal Fixation
Devices by Geographic Region - Percentage Breakdown of Dollar
Sales for US, Europe, Asia-Pacific and Rest of World Markets
for Years 2008, 2011 & 2017 (includes corresponding
Graph/Chart) 103

Table 12: World Recent Past, Current & Future Market Analysis
for Artificial Discs by Geographic Region -US, Europe,
Asia-Pacific and Rest of World Independently Analyzed with
Annual Sales Figures in US$ million for Years 2008 through
2017 (includes corresponding Graph/Chart) 104

Table 13: World 10-Year Perspective for Artificial Discs by
Geographic Region - Percentage Breakdown of Dollar Sales for
US, Europe, Asia-Pacific and Rest of World Markets for Years
2008, 2011 & 2017 (includes corresponding Graph/Chart) 105

Table 14: World Recent Past, Current & Future Market Analysis
for Vertebral Compression Fracture Devices by Geographic
Region -US, Europe, Asia-Pacific and Rest of World
Independently Analyzed with Annual Sales Figures in US$
million for Years 2008 through 2017 (includes corresponding
Graph/Chart) 106

Table 15: World 10-Year Perspective for Vertebral Compression
Fracture Devices by Geographic Region - Percentage Breakdown
of Dollar Sales for US, Europe, Asia-Pacific and Rest of World
Markets for Years 2008, 2011 & 2017 (includes corresponding
Graph/Chart) 107

13. THE UNITED STATES 108
A.Market Analysis 108
Market Statistics 108
Spinal Products Market 108
Low Back Pain Prevalent in the US 109
Table 16: Leading Players in the US Spinal Surgery Devices
Market (2008); Percentage Share Breakdown of Revenues for
Medtronic, Depuy orthopedics, Synthes, Stryker and Others
(includes corresponding Graph/Chart) 109
Spinal Procedures in US Witness Substantial Growth 110
Spinal Non-Fusion Devices Market to Grow Exponentially 110
US Market for MIVCF Treatments to Grow at a Slower Rate 110
Table 17: Kyphoplasty Procedures in the US (2006 -2010P)
(includes corresponding Graph/Chart) 111
Minimally Invasive Spinal Surgery Market: An Overview 111
Facet Fixation Market: Driven by Innovation 111
Disc Replacements: The New Buzz 112
Competition 112
Spinal Fusion Market 112
Table 18: Leading Players in the US Spinal Fusion Devices
Market (2010): Percentage Share Breakdown of Revenues for
Medtronic, DePuy Spine, Stryker Spine, Zimmer, Biomet and
Others (includes corresponding Graph/Chart) 113
Spinal Fixation Market 113
Table 19: Leading Players in the US Spinal Fixation Devices
Market (2010): Percentage Share Breakdown of Revenues for
Medtronic, DePuy Spine, Synthes, Stryker Spine, Biomet,
Zimmer and Others (includes corresponding Graph/Chart) 113
Vertebral Compression Fracture Devices Market 113
Reimbursement Scenario 114
Product Approval/Launches 115
Strategic Corporate Developments 143
Review of Major Players 158
B.Market Analytics 166
Table 20: US Recent Past, Current & Future Market Analysis
for Spinal Surgery Devices by Product Segment - Spinal
Fusion Devices, Spinal Fixation Devices, Artificial Discs
and Vertebral Compression Fracture Devices Markets
Independently Analyzed with Annual Sales Figures in US$
million for Years 2008 through 2017 (includes corresponding
Graph/Chart) 166

Table 21: US 10-Year Perspective for Spinal Surgery Devices
by Product Segment - Spinal Fusion Devices, Spinal Fixation
Devices, Artificial Discs and Vertebral Compression Fracture
Devices Markets for 2008, 2011 & 2017 (includes
corresponding Graph/Chart) 167

14. EUROPE 168
A.Market Analysis 168
Market Overview 168
Product Approval/Launches 168
Strategic Corporate Developements 169
B.Market Analytics 170
Table 22: European Recent Past, Current & Future Market
Analysis for Spinal Surgery Devices by Product Segment -
Spinal Fusion Devices, Spinal Fixation Devices, Artificial
Discs and Vertebral Compression Fracture Devices Markets
Independently Analyzed with Annual Sales Figures in US$
million for Years 2008 through 2017 (includes corresponding
Graph/Chart) 170

Table 23: European 10-Year Perspective for Spinal Surgery
Devices by Product Segment - Spinal Fusion Devices, Spinal
Fixation Devices, Artificial Discs and Vertebral Compression
Fracture Devices Markets for 2008, 2011 & 2017 (includes
corresponding Graph/Chart) 171

Table 24: European Recent Past, Current & Future Market
Analysis for Spinal Surgery Devices by Geographic Region -
France, Germany, Italy, UK and Rest of Europe Markets
Independently Analyzed with Annual Sales Figures in US$
million for Years 2008 through 2017 (includes corresponding
Graph/Chart) 172

Table 25: European 10-Year Perspective for Spinal Surgery
Devices by Geographic Region - Percentage Breakdown of
Dollar Sales for France, Germany, Italy, UK and Rest of
Europe Markets for Years 2008, 2011 & 2017 (includes
corresponding Graph/Chart) 173

14a. FRANCE 174
A.Market Analysis 174
Product Approval/Launches 174
Strategic Corporate Developments 175
Review of Major Players 175
B.Market Analytics 177
Table 26: French Recent Past, Current & Future Market
Analysis for Spinal Surgery Devices by Product Segment -
Spinal Fusion Devices, Spinal Fixation Devices and Vertebral
Compression Fracture Devices Markets Independently Analyzed
with Annual Sales Figures in US$ million for Years 2008
through 2017 (includes corresponding Graph/Chart) 177

Table 27: French 10-Year Perspective for Spinal Surgery
Devices by Product Segment - Spinal Fusion Devices, Spinal
Fixation Devices and Vertebral Compression Fracture Devices
Markets for 2008, 2011 & 2017 (includes corresponding
Graph/Chart) 178

14b. GERMANY 179
Market Analysis 179
Table 28: German Recent Past, Current & Future Market
Analysis for Spinal Surgery Devices by Product Segment -
Spinal Fusion Devices, Spinal Fixation Devices and Vertebral
Compression Fracture Devices Markets Independently Analyzed
with Annual Sales Figures in US$ million for Years 2008
through 2017 (includes corresponding Graph/Chart) 179

Table 29: German 10-Year Perspective for Spinal Surgery
Devices by Product Segment - Spinal Fusion Devices, Spinal
Fixation Devices and Vertebral Compression Fracture Devices
Markets for 2008, 2011 & 2017 (includes corresponding
Graph/Chart) 180

14c. ITALY 181
A.Market Analysis 181
Product Approval/Launches 181
B.Market Analytics 182
Table 30: Italian Recent Past, Current & Future Market
Analysis for Spinal Surgery Devices by Product Segment -
Spinal Fusion Devices, Spinal Fixation Devices and Vertebral
Compression Fracture Devices Markets Independently Analyzed
with Annual Sales Figures in US$ million for Years 2008
through 2017 (includes corresponding Graph/Chart) 182

Table 31: Italian 10-Year Perspective for Spinal Surgery
Devices by Product Segment - Spinal Fusion Devices, Spinal
Fixation Devices and Vertebral Compression Fracture Devices
Markets for 2008, 2011 & 2017 (includes corresponding
Graph/Chart) 183

14d. THE UNITED KINGDOM 184
A.Market Analysis 184
Product Approval/Launches 184
Strategic Corporate Developments 184
Smith & Nephew Plc - A Key Player 185
B.Market Analytics 186
Table 32: United kingdom Recent Past, Current & Future
Market Analysis for Spinal Surgery Devices by Product
Segment - Spinal Fusion Devices, Spinal Fixation Devices and
Vertebral Compression Fracture Devices Markets Independently
Analyzed with Annual Sales Figures in US$ million for Years
2008 through 2017 (includes corresponding Graph/Chart) 186

Table 33: United Kingdom 10-Year Perspective for Spinal
Surgery Devices by Product Segment - Spinal Fusion Devices,
Spinal Fixation Devices and Vertebral Compression Fracture
Devices Markets for 2008, 2011 & 2017 (includes
corresponding Graph/Chart) 187

14e. REST OF EUROPE 188
A.Market Analysis 188
Review of Select Regions 188
Czech Republic 188
Hungary 188
Strategic Corporate Developments 188
B.Market Analytics 189
Table 34: Rest of European Recent Past, Current & Future
Market Analysis for Spinal Surgery Devices by Product
Segment - Spinal Fusion Devices, Spinal Fixation Devices and
Vertebral Compression Fracture Devices Markets Independently
Analyzed with Annual Sales Figures in US$ million for Years
2008 through 2017 (includes corresponding Graph/Chart) 189

Table 35: Rest of European 10-Year Perspective for Spinal
Surgery Devices by Product Segment - Spinal Fusion Devices,
Spinal Fixation Devices and Vertebral Compression Fracture
Devices Markets for 2008, 2011 & 2017 (includes
corresponding Graph/Chart) 190

15. ASIA-PACIFIC 191
A.Market Analysis 191
Asia-Pacific: A Promising Market for Spinal Implants 191
Key Players Eye Asia 191
Overview of the Minimally Invasive Surgery Market 191
Competition 192
Table 36: Leading Players in the Asia-Pacific Spinal
Surgery Market (2010): Percentage Share Breakdown of
Revenues for Medtronic, Synthes, DePuy, Stryker, Zimmer and
Others (includes corresponding Graph/Chart) 192
Review of Select Regions 192
Japan 192
Market Analysis 192
Market Overview 193
Table 37: Japanese Recent Past, Current & Future Market
Analysis for Spinal Surgery Devices by Product Segment -
Spinal Fusion Devices, Spinal Fixation Devices and
Vertebral Compression Fracture Devices Markets
Independently Analyzed with Annual Sales Figures in US$
million for Years 2008 through 2017 (includes
corresponding Graph/Chart) 193

Table 38: Japanese 10-Year Perspective for Spinal Surgery
Devices by Product Segment - Spinal Fusion Devices,
Spinal Fixation Devices and Vertebral Compression
Fracture Devices Markets for 2008, 2011 & 2017 (includes
corresponding Graph/Chart) 194
China 194
Thailand 195
Product Approval / Launches 195
Strategic Corporate Developments 196
B.Market Analytics 197
Table 39: Asia-Pacific Recent Past, Current & Future Market
Analysis for Spinal Surgery Devices by Product Segment -
Spinal Fusion Devices, Spinal Fixation Devices, Artificial
Discs and Vertebral Compression Fracture Devices Markets
Independently Analyzed with Annual Sales Figures in US$
million for Years 2008 through 2017 (includes corresponding
Graph/Chart) 197

Table 40: Asia-Pacific 10-Year Perspective for Spinal
Surgery Devices by Product Segment - Spinal Fusion Devices,
Spinal Fixation Devices, Artificial Discs and Vertebral
Compression Fracture Devices Markets for 2008, 2011 & 2017
(includes corresponding Graph/Chart) 198

16. REST OF WORLD 199
A.Market Analysis 199
Spinal Implants Market to Witness Exponential Growth 199
Strategic Corporate Developments 199
B.Market Analytics 202
Table 41: Rest of World Recent Past, Current & Future Market
Analysis for Spinal Surgery Devices by Product Segment -
Spinal Fusion Devices, Spinal Fixation Devices, Artificial
Discs and Vertebral Compression Fracture Devices Markets
Independently Analyzed with Annual Sales Figures in US$
million for Years 2008 through 2017 (includes corresponding
Graph/Chart) 202

Table 42: Rest of World 10-Year Perspective for Spinal
Surgery Devices by Product Segment - Spinal Fusion Devices,
Spinal Fixation Devices, Artificial Discs and Vertebral
Compression Fracture Devices Markets for 2008, 2011 & 2017
(includes corresponding Graph/Chart) 203


COMPETITIVE LANDSCAPE

Total Companies Profiled: 92 (including Divisions/Subsidiaries - 123)

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Region/Country Players
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The United States 86
Canada 1
Europe 28
France 4
Germany 6
The United Kingdom 9
Rest of Europe 9
Asia-Pacific (Excluding Japan) 2
Latin America 1
Africa 1
Middle East 4
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