Global Cardiac Rhythm Management (CRM) Devices Industry

• Publication date: October 2011

This report analyzes the worldwide markets for Cardiac Rhythm Management (CRM) Devices in US$ Million by the following Product Segments: Implantable Cardioverter Defibrillators (ICD), Pacemakers, External Defibrillators, and EP Catheterization, Mapping, and Ablation (CMA) devices. The report provides separate comprehensive analytics for the US, Europe, Asia-Pacific, and Rest of World. Annual estimates and forecasts are provided for the period ...

This report analyzes the worldwide markets for Cardiac Rhythm Management (CRM) Devices in US$ Million by the following Product Segments: Implantable Cardioverter Defibrillators (ICD), Pacemakers, External Defibrillators, and EP Catheterization, Mapping, and Ablation (CMA) devices. The report provides separate comprehensive analytics for the US, Europe, Asia-Pacific, and Rest of World. Annual estimates and forecasts are provided for the period 2009 through 2017. A six-year historic analysis is also provided for these markets. The report profiles 48 companies including many key and niche players such as Bard Electrophysiology, Biosense Webster, Inc., Biotronik GMBH & Co. KG, Boston Scientific Corporation, Medtronic, Inc., Medtronic CryoCath LP, Vitatron Nederland BV, Philips Healthcare, St. Jude Medical, Inc., and Sorin Group. Market data and analytics are derived from primary and secondary research. Company profiles are mostly extracted from URL research and reported select online sources.

Global Cardiovascular Devices Industry

1. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS 1
Study Reliability and Reporting Limitations 1
Disclaimers 2
Data Interpretation & Reporting Level 2
Quantitative Techniques & Analytics 3
Product Definitions and Scope of Study 3
Implantable Cardioverter Defibrillators (ICD) 3
Pacemaker 4
External Defibrillators 4
Electrophysiology (EP) Catheterization, Mapping, and Ablation
(CMA) 4

2. INDUSTRY OVERVIEW 5
A Prelude 5
Cardiac Rhythm Management Devices - An Outlook 5
Implantable Cardioverter Defibrillators 5
Pacemakers 6
External Defibrillators 6
EP Catheterization, Mapping, & Ablation (CMA) 6
Market Structure 6
Table 1: World Market for Cardiac Rhythm Management (CRM)
Devices (2010): Percentage Breakdown of Annual Revenues by
Companies (includes corresponding Graph/Chart) 7

Table 2: World Market for High Power CRM Devices (2010):
Percentage Breakdown of Annual Revenues by Companies.
(includes corresponding Graph/Chart) 7

Table 3: World Market for Low Power CRM Devices (2010):
Percentage Breakdown of Annual Revenues by Companies(includes
corresponding Graph/Chart) 7

Table 4: World Market for Implantable Cardioverter
Defibrillator (2010): Percentage Breakdown of Annual Revenues
by Companies (includes corresponding Graph/Chart) 8

Table 5: World External Defibrillators Market (2010):
Percentage Market Share Breakdown of Leading Players -
Medtronic, Philips and Others (includes corresponding
Graph/Chart) (includes corresponding Graph/Chart) 8

Table 6: World Market for Advanced Cardiac Resynchronization
Therapy (CRT) Devices (2010): Percentage Market Share
Breakdown of Leading Players - Medtronic, Boston Scientific
(Guidant), St. Jude Medical, and Others (includes
corresponding Graph/Chart) 8

3. TRENDS & ISSUES 9
SSS and AV Block Incidence Triggers Demand for Pacemakers 9
Infamous Product Recalls Throw Growth Off-track 9
Market Shapes Up After the Recall Shock 10
Regulatory Riders Knit to Ensure Greater Device Reliability 10
Growing Proportion of Obese Population: A Major Demographic
Driver 10
Replacements to Drive the Growth of ICDs 11
Developments in Energy-Based Therapies Augur Well for Cardiac
Ablation Treatments 11
Expanding Applications Lend Traction to Growth 12
Prices of Cardiac Pacemakers Soften 12
Heart Patients Using ICD, Enjoy Satisfactory Quality Life 12
Pacemakers Ensure Effective Management of Non-Systolic Heart
Failures 13
CRT: An Effective Treatment for Bradycardia, Tachycardia &
Fibrillation 13
ICDs in Pediatric Care Shows Promise 13
Emerging Therapies for the Treatment of Atrial Fibrillation 14
New Generation CRM Devices Feature Superior Benefits 14
MRI-Compatible Pacemakers & ICDs 14
Resistance Against Electronic Interferences 15
Confusion Over the Use of CRM Devices Threaten Perceived
Effectiveness 15
Breathing Disorders in Patients Implanted with Pacemakers: A
Cause for Concern 16
Approval of Untested Pacemaker Connectors Raises Eyebrows 17
ICD Lead Failure Demands Immediate Attention 17
Pacemaker Hacking Has the Industry Up by Its Ears 17
Pacemakers Face Stiff Competition from CRT-D Devices 18
ICDs More Prone to Malfunction than Pacemakers 18
Conclusion 19
Technology Innovation: A Futuristic Rumination 19
The Heart to Power CRM Devices: The Future of CRM Therapies 19
Genetic Advances to Yield Replacement for Pacemakers 19
Ablation Technology Undergoing Innovations 20
Vein Ablation Catheter Proves Successful in Cases of
Paroxysmal Atrial Fibrillation 20
Ablation Therapy Useful in Treating Persistent/ Permanent
Atrial Fibrillation (PPAF) 20
Magnetic Navigation: An Innovation in Catheter Ablation 21
New Force-Sensing Ablation Catheter Aims to Aid Physician
Decision Making 21
Pricing & Reimbursements: Critical Determinants of Growth 22
New Guidelines Issued for Safe Management of CRM Devices in
the US and Europe 22

4. PRODUCT OVERVIEW 24
Sudden Cardiac Arrest: A Leading Cause of Death 24
Cardiac Rhythm Management (CRM): A Definition 24
Implantable Cardioverter Defibrillators (ICDs) 24
Surgical Implantation of ICDs: The Procedure 25
ICDs - The Benefits 25
Types of ICDs 26
ICDs: An Evolution Scan 26
Complications Associated With ICD Usage 26
CRT-D - A New Therapeutic Device 26
Pacemakers 27
Surgical Implantation of Pacemakers: The Procedure 27
Types of Pacemakers 27
Methods of Pacing 28
Fixed Rate Pacemakers 28
Demand Pacemakers 28
Rate-Responsive Pacemaker 28
Pacemakers: An Evolution Scan 28
Complications Associated with Pacemakers 29
Advent of CRT-P 29
Electrophysiology (EP) Catheterization, Mapping, and Ablation
(CMA) 29
The Ablation Procedure 30
External Defibrillators 30
Types of AEDs 31
Cardiac Rhythm Disorders: A Brief Review 31
Cardiac Arrhythmias 31
Classification of Cardiac Arrhythmias 32
Bradycardia 32
Tachycardia 32
Atrial Fibrillation 33
Heart Blocks 34
Syncope 34
Sick Sinus Syndrome 34
Cardiomyopathy 34

5. PRODUCT APPROVALS/INTRODUCTIONS 35
Boston Scientific Unveils CRM Connector System 35
Biosense Catheter Receives FDA Marketing Approval 35
St. Jude Medical Secures Approval for Atlas II ICD from Japan 35
Zoll Medical Defibrillators Receive FDA Clearance 35
St. Jude Medical Receives CE Mark for Integrated Irrigation
Pump and Ablation Generator 36
AtriCure Secures FDA 510(k) Approval for Coolrail Device 36
Hansen Medical Gains FDA Approval for CoHesion™ Module 37
St. Jude Medical Obtains CE Mark and FDA Approval for HIFU
Surgical Ablation Solutions 37
Biosense Releases NAVISTAR® RMT THERMOCOOL® Catheter 37
Atricure Unveils The ORLab™ 38
Cardima Receives SFDA Approval to Market INTELLITEMP® in China 38
ZOLL Obtains 510K Clearance to Sell and Market Zoll R Series
Code-Ready Defibrillator 38
ST. Jude Medical Obtains FDA and CE Mark Approval for New
Epicor LP Cardiac Ablation System 39
Cardima Obtains Approval for Marketing Surgical Ablation
System in Thailand 39
ATS Medical Introduces First CryoMaze Surgical Ablation Clamp 39
CardioNet Unveils New Reporting Package for Atrial
Fibrillation Treatment 40
Boston Scientific Defibrillator Receives CE Mark Approval 40
TyRx Introduces New Anti-bacterial Envelope, AIGISRX™ ICD 40
St. Jude Medical Receives Approval from Japanese MHLW 41
Boston Scientific Secures FDA Approval for CRM Solutions 41
Sorin Group Develops New-Generation CRT-D Implants 41
BSC Secures CE Mark Approval for ALTRUA Pacemakers 42
Medtronic Secures FDA Approval for New Vision 3D Devices 42
Medtronic Obtains FDA Approval for Software Update 43
St. Jude Medical Obtains FDA Approval for SJM Cardiac Monitor 43
Boston Scientific Obtains Approval For Cognis CRT-D And
Teligen ICD 43
FDA Approves Medtronic’s Medtronic Sprint Quattro Secure® S Lead 43
Medtronic Obtains CE Mark Approval for Pacemaker and Pacing Leads 44
St. Jude Medical Obtains Japanese Approval for Victory®
Pacemakers Family 44
Sorin Group Obtains Approval For Isoline Defibrillation Leads
In Japan 44
BSC Secures FDA Approval for New ALTRUA Pacemakers 45
St. Jude Medical Obtains Approval for Durata Defibrillation Lead 46
St. Jude Medical Obtains Japanese Approval for Durata
Defibrillation Lead 46
St. Jude Medical Obtains Japanese Approval for Victory Family
of Pacemakers 46
Sorin Group Gains FDA Approval for OVATIO™ 46
Sorin SpA Gains FDA Approval for REPLY 47
Medtronic Receives Approval for Lead Integrity Alert™ 47
Physio-Control Gains FDA Approval for LIFEPAK® 20e
Defibrillator/Monitor 47
TyRx Introduces New Anti-Bacterial Envelope, AIGISRX™ ICD 48
LifeWatch Introduces Next-Generation Monitor, LifeStar ACT III
Platinum 48
eCardio Launches eVolution, New Cardiac Monitoring System 48
Philips Introduces PageWriter TC70 Cardiograph 49
Sorin Group Announces Commercial Release and First Implant of
PARADYM™ CRT 8750 49
St. Jude Medical Introduces QuickOpt® Timing Cycle
Optimization in CRT-D 49
Cardiac Science Unveils Simple Electronic Reporting System 50
Mennen Medical Introduces VitaLogik® 4000 Line 50
BIOTRONIK Releases CRT-P in US Market 51
Vermed Releases Defibrillation Pads Series and Universal
Connector System 51
St. Jude Releases Reflexion Spiral X™ in US 52

6. RECENT INDUSTRY ACTIVITY 53
Novation Partners St. Jude Medical for CRM Products 53
Medtronic Sets Up Production Unit in Singapore 53
Novation Collaborates with BIOTRONIK 53
Boston Scientific Inks Agreement with Fukuda Denshi 53
Creganna Closes Tactx Medical Acquisition 54
Medtronic Takes Over Ablation Frontiers 54
Sorin Enters into Agreement with Orange Business Services 54
Philips Signs a Deal with Bard Electrophysiology 55
Boston Scientific Bags CRM Contract from Dept. of Veterans
Affairs 55
Medtronic and Boston Scientific Inks Agreement to End IP Disputes 55
St Jude Medical to Invest in Penang 56
Cardima Enters into a Distribution Agreement with Peerless
Medical 56
Cardiac Science Enters into an Alliance with Boy Scouts of
America 56
Cardima Enters into a New Strategic Surgical Alliance with
Biocore 57
Cardima Enters into a New Strategic Marketing Alliance with
On-X Life Technologies 57
Welch Allyn and ZOLL Medical Corporation Collaborate 58
Cardima Selects Dot Medical to Distribute Its EP Products in
the UK 58
Royal Philips to Guide ‘euHeart’ Project 59
Target Center Acquires HeartSine® Defibrillators 59
St Jude Medical Acquires EP MedSystems 59
St. Jude Takes Over Radi Medical AB 59
Medrad to Acquire Possis 60
Phoenix Acquires Stake in Possis 60
Biotronik Acquires VascoMed 60
Medtronic Takes Over CryoCath Technologies 61
Boston Scientific Takes Over CryoCor 61
St. Jude Completes Acquisition of MediGuide 61
Greatbatch Enters Into A Strategic Partnership With Issys 61
Sorin Group Inks Collaborative Agreement with Greatbatch 62
Philips Enters into MOU with King’s College London on Research
Collaboration 62
Welch Allyn Collaborates with ZOLL Medical Corporation 62
ZOLL and HealthTrust Sign Purchasing Deal 63
ZOLL Inks Multi-Year Agreement with Masimo 63
First Responder Wins Contract from Harvard School of Public
Health 63
Beijing Airport Group to Deploy ZOLL AED Plus Solutions 63
STH NHS Trust to Deploy New R Series BLS Solutions of ZOLL 64
Major EMS Centers in China Deploys ZOLL M Series Defibrillator 64
DRF to Deploy corpuls3 Heart Defibrillators 65
Riedel & Schulz and GS Elektromed Distributes 8 corpuls3
Medical Units 65
Trivitron Inks Marketing And Distribution Agreement With
Boston Scientific 65
CardioComm Signs Licensing Agreement with GE Healthcare 65
Cambridge Heart Licenses Technology for Implantable Devices 65
Synovis Life Technologies to Divest Interventional Business 66
Boston Scientific Divests Cardiac Surgery And Vascular Surgery
Businesses 66
Sorin Group Sells Its Vascular Therapy Business to CIDl 66

7. FOCUS ON SELECT PLAYERS 67
Bard Electrophysiology (US) 67
Biosense Webster, Inc. (US) 67
Biotronik GMBH & Co. KG (Germany) 67
Boston Scientific Corporation (US) 67
Medtronic, Inc. (US) 68
Medtronic CryoCath LP (US) 68
Vitatron Nederland BV (Netherlands) 68
Philips Healthcare (The Netherlands) 69
St. Jude Medical, Inc. (US) 69
Sorin Group (Italy) 69

8. GLOBAL MARKET PERSPECTIVE 70
Table 7: World Recent Past, Current & Future Analysis for
Cardiac Rhythm Management Devices by Geographic Region - US,
Europe, Asia-Pacific and Rest of World Markets Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2009 through 2017 (includes corresponding Graph/Chart) 70

Table 8: World Historic Review for Cardiac Rhythm Management
Devices by Geographic Region - US, Europe, Asia-Pacific and
Rest of World Markets Independently Analyzed with Annual Sales
Figures in US$ Million for Years 2003 through 2008 (includes
corresponding Graph/Chart) 71

Table 9: World 15-Year Perspective for Cardiac Rhythm
Management Devices by Geographic Region - Percentage Breakdown
of Dollar Sales for US, Europe, Asia-Pacific and Rest of World
Markets for Years 2003, 2010 & 2017 (includes corresponding
Graph/Chart) 72

Table 10: World Recent Past, Current & Future Analysis for
Implantable Cardioverter Defibrillators by Geographic Region -
US, Europe, Asia-Pacific and Rest of World Markets
Independently Analyzed with Annual Sales Figures in US$
Million for Years 2009 through 2017 (includes corresponding
Graph/Chart) 73

Table 11: World Historic Review for Implantable Cardioverter
Defibrillators by Geographic Region - US, Europe, Asia-Pacific
and Rest of World Markets Independently Analyzed with Annual
Sales Figures in US$ Million for Years 2003 through 2008
(includes corresponding Graph/Chart) 74

Table 12: World 15-Year Perspective for Implantable
Cardioverter Defibrillators by Geographic Region - Percentage
Breakdown of Dollar Sales for US, Europe, Asia-Pacific and
Rest of World Markets) for Years 2003, 2010 & 2017 (includes
corresponding Graph/Chart) 75

Table 13: World Recent Past, Current & Future Analysis for
Pacemakers by Geographic Region - US, Europe, Asia- Pacific
and Rest of World Markets Independently Analyzed with Annual
Sales Figures in US$ Million for Years 2009 through 2017
(includes corresponding Graph/Chart) 76

Table 14: World Historic Review for Pacemakers by Geographic
Region - US, Europe, Asia-Pacific and Rest of World Markets
Independently Analyzed with Annual Sales Figures in US$
Million for Years 2003 through 2008 (includes corresponding
Graph/Chart) 77

Table 15: World 15-Year Perspective for Pacemakers by
Geographic Region - Percentage Breakdown of Dollar Sales for
US, Europe, Asia-Pacific and Rest of World Markets) for Years
2003, 2010 & 2017 (includes corresponding Graph/Chart) 78

Table 16: World Recent Past, Current & Future Analysis for
External Defibrillators by Geographic Region - US, Europe,
Asia-Pacific and Rest of World Markets Independently Analyzed
with Annual Sales Figures in US$ Million for Years 2009
through 2017 (includes corresponding Graph/Chart) 79

Table 17: World Historic Review for External Defibrillators by
Geographic Region - US, Europe, Asia-Pacific and Rest of World
Markets Independently Analyzed with Annual Sales Figures in
US$ Million for Years 2003 through 2008 (includes
corresponding Graph/Chart) 80

Table 18: World 15-Year Perspective for External
Defibrillators by Geographic Region - Percentage Breakdown of
Dollar Sales for US, Europe, Asia-Pacific and Rest of World
Markets) for Years 2003, 2010 & 2017 (includes corresponding
Graph/Chart) 81

Table 19: World Recent Past, Current & Future Analysis for EP
Catheterization, Mapping, & Ablation (CMA) by Geographic
Region - US, Europe, Asia-Pacific and Rest of World Markets
Independently Analyzed with Annual Sales Figures in US$
Million for Years 2009 through 2017 (includes corresponding
Graph/Chart) 82

Table 20: World Historic Review for EP Catheterization,
Mapping, & Ablation (CMA)by Geographic Region - US, Europe,
Asia-Pacific and Rest of World Markets Independently Analyzed
with Annual Sales Figures in US$ Million for Years 2003
through 2008 (includes corresponding Graph/Chart) 83

Table 21: World 15-Year Perspective for EP Catheterization,
Mapping, & Ablation (CMA) by Geographic Region - Percentage
Breakdown of Dollar Sales for US, Europe, Asia-Pacific and
Rest of World Markets) for Years 2003, 2010 & 2017 (includes
corresponding Graph/Chart) 84

9. THE UNITED STATES 85
A.Market Analysis 85
Outlook 85
Market Overview 85
Demand for Automated External Defibrillators Shoots Up in
the US 85
Market Share Statistics 86
Table 22: US Market for (ICD) Implantable Cardioverter
Defibrillators (2011): Percentage Breakdown of Annual
Revenues by Companies (includes corresponding Graph/Chart) 86

Table 23: US Market for Core Pacemakers & CRT-P (2010):
Percentage Breakdown of Annual Revenues by Companies
(includes corresponding Graph/Chart) 86
Cardiovascular Disease Incidence Statistics 86
Table 24: Cardiovascular Diseases in US (2010): Percentage
Breakdown of Total Economic Cost Incurred for Treatment by
Disease Type (includes corresponding Graph/Chart) 86

Table 25: Cardiovascular Diseases in US (2010): Percentage
Breakdown of Total Economic Cost Incurred for Treatment by
Type of Expenditure (includes corresponding Graph/Chart) 87

Table 26: Cardiovascular Diseases (CvD) in US (2010):
Incidence of CvDs in Adult Population Segregated by Age
and Gender (includes corresponding Graph/Chart) 87

Table 27: Cardiovascular Diseases (CvD) in the US (2010):
Percentage Breakdown of Deaths by Type of Causal CvD
(includes corresponding Graph/Chart) 88
B.Market Analytics 89
Table 28: US Recent Past, Current & Future Analysis for
Cardiac Rhythm Management Devices by Product Segment -
Implantable Cardioverter Defibrillators, Pacemakers,
External Defibrillators, and EP Catheterization, Mapping,
and Ablation (CMA) Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2009 through
2017 (includes corresponding Graph/Chart) 89

Table 29: US Historic Review for Cardiac Rhythm Management
Devices by Product Segment - Implantable Cardioverter
Defibrillators, Pacemakers, External Defibrillators, and EP
Catheterization, Mapping, and Ablation (CMA) Markets
Independently Analyzed with Annual Sales Figures in US$
Million for Years 2003 through 2008 (includes corresponding
Graph/Chart) 90

Table 30: US 15-Year Perspective for Cardiac Rhythm
Management Devices by Product Segment - Percentage Breakdown
of Dollar Sales for Implantable Cardioverter Defibrillators,
Pacemakers, External Defibrillators, and EP Catheterization,
Mapping, and Ablation (CMA) for Years 2003, 2010 & 2017
(includes corresponding Graph/Chart) 91

10. EUROPE 92
A.Market Analysis 92
Outlook 92
Major Market Trends 92
Flourishing Market for CRM Market in Western Europe 92
Bright Future for CRM Devices Industry 92
Highly Competitive External Defibrillators Market Paves Way
for Consolidations 93
Strong Demand for Implantable Cardiac Defibrillators in UK 93
B.Market Analytics 94
Table 31: European Recent Past, Current & Future Analysis
for Cardiac Rhythm Management Devices by Product Segment -
Implantable Cardioverter Defibrillators, Pacemakers,
External Defibrillators, and EP Catheterization, Mapping,
and Ablation (CMA) Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2009 through
2017 (includes corresponding Graph/Chart) 94

Table 32: European Historic Review for Cardiac Rhythm
Management Devices by Product Segment - Implantable
Cardioverter Defibrillators, Pacemakers, External
Defibrillators, and EP Catheterization, Mapping, and
Ablation (CMA) Markets Independently Analyzed with Annual
Sales Figures in US$ Million for Years 2003 through 2008
(includes corresponding Graph/Chart) 95

Table 33: European 15-Year Perspective for Cardiac Rhythm
Management Devices by Product Segment - Percentage Breakdown
of Dollar Sales for Implantable Cardioverter Defibrillators,
Pacemakers, External Defibrillators, and EP Catheterization,
Mapping, and Ablation (CMA) for Years 2003, 2010 & 2017
(includes corresponding Graph/Chart) 96

11. ASIA PACIFIC 97
A.Market Analysis 97
Outlook 97
Major Market Trends 97
Increasing Heart Diseases Spur Demand for CRM Devices 97
Chinese CRM Market to Witness Robust Growth 97
B.Market Analytics 98
Table 34: Asia Pacific Recent Past, Current & Future
Analysis for Cardiac Rhythm Management Devices by Product
Segment - Implantable Cardioverter Defibrillators,
Pacemakers, External Defibrillators, and EP Catheterization,
Mapping, and Ablation (CMA) Markets Independently Analyzed
with Annual Sales Figures in US$ Million for Years 2009
through 2017 (includes corresponding Graph/Chart) 98

Table 35: Asia Pacific Historic Review for Cardiac Rhythm
Management Devices by Product Segment - Implantable
Cardioverter Defibrillators, Pacemakers, External
Defibrillators, and EP Catheterization, Mapping, and
Ablation (CMA) Markets Independently Analyzed with Annual
Sales Figures in US$ Million for Years 2003 through 2008
(includes corresponding Graph/Chart) 99

Table 36: Asia Pacific 15-Year Perspective for Cardiac
Rhythm Management Devices by Product Segment - Percentage
Breakdown of Dollar Sales for Implantable Cardioverter
Defibrillators, Pacemakers, External Defibrillators, and EP
Catheterization, Mapping, and Ablation (CMA) for Years 2003,
2010 & 2017 (includes corresponding Graph/Chart) 100

12. REST OF WORLD 101
A.Market Analysis 101
Outlook 101
Market Share Statistics 101
Table 37: Implantable Cardioverter Defibrillator (ICD)
Market in EMEA, Asia, & South America (2010): Percentage
Market Share Breakdown of Leading Players - Medtronic,
Boston Scientific (Guidant), St Jude Medical, and Others
(includes corresponding Graph/Chart) 101

Table 38: Core Pacemakers & CRT-P Market in EMEA, Asia, &
South America (2010): Percentage Market Share Breakdown of
Leading Players - Medtronic, St. Jude, Boston Scientific
and Others (includes corresponding Graph/Chart) 101
B.Market Analytics 102
Table 39: Rest of World Recent Past, Current & Future
Analysis for Cardiac Rhythm Management Devices by Product
Segment - Implantable Cardioverter Defibrillators,
Pacemakers, External Defibrillators, and EP Catheterization,
Mapping, and Ablation (CMA) Markets Independently Analyzed
with Annual Sales Figures in US$ Million for Years 2009
through 2017 (includes corresponding Graph/Chart) 102

Table 40: Rest of World Historic Review for Cardiac Rhythm
Management Devices by Product Segment - Implantable
Cardioverter Defibrillators, Pacemakers, External
Defibrillators, and EP Catheterization, Mapping, and
Ablation (CMA) Markets Independently Analyzed with Annual
Sales Figures in US$ Million for Years 2003 through 2008
(includes corresponding Graph/Chart) 103

Table 41: Rest of World 15-Year Perspective for Cardiac
Rhythm Management Devices by Product Segment - Percentage
Breakdown of Dollar Sales for Implantable Cardioverter
Defibrillators, Pacemakers, External Defibrillators, and EP
Catheterization, Mapping, and Ablation (CMA) for Years 2003,
2010 & 2017 (includes corresponding Graph/Chart) 104


COMPETITIVE LANDSCAPE

Total Companies Profiled: 48 (including Divisions/Subsidiaries - 125)

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Region/Country Players
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The United States 30
Canada 7
Japan 8
Europe 67
France 8
Germany 13
The United Kingdom 8
Italy 7
Spain 5
Rest of Europe 26
Asia-Pacific (Excluding Japan) 10
Latin America 2
Africa 1
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