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Global Mechanical Ventilator Industry

  • March 2016
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  • Global Industry Analysts
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  • 273 pages

This report analyzes the worldwide markets for Mechanical Ventilators in US$ Thousand by the following Product Segments: Critical Care, Neonatal, and Portable & Transport Ventilators. The report provides separate comprehensive analytics for the US, Canada, Japan, Europe, Asia-Pacific, Middle East & Africa, and Latin America. Annual estimates and forecasts are provided for the period 2015 through 2022. Also, a six-year historic analysis is provided for these markets. Market data and analytics are derived from primary and secondary research. Company profiles are primarily based on public domain information including company URLs. The report profiles 61 companies including many key and niche players such as -

CareFusion Corp. A BD Company
Medtronic Plc
Dräger Medical, Inc.
Fisher & Paykel Healthcare Corp. Limited
GE Healthcare

Table Of Contents

Global Mechanical Ventilator Industry


I. INTRODUCTION, METHODOLOGY and PRODUCT DEFINITIONS

Study Reliability and Reporting Limitations I-1 Disclaimers.............. I-2 Data Interpretation and Reporting Level I-2 Quantitative Techniques and Analytics I-3 Product Definitions and Scope of Study I-3 Critical Care Ventilators..............I-3 Neonatal Ventilators..............I-3 Portable and Transport Ventilators I-3

II.EXECUTIVE SUMMARY

1. INDUSTRY OVERVIEW.............. II-1 A Prelude to Mechanical Ventilators II-1 Rising Incidence of COPD to Drive Growth II-2 Quick COPD Facts:..............II-3 Table 1: Global Prevalence of COPD by Age Group (2015): Percentage of Men and Women Affected by the Condition (includes corresponding Graph/Chart) II-3

Table 2: Mortality Rates of COPD ('000s) by Select Geographic Region (includes corresponding Graph/Chart) II-4 US Leads the Global Mechanical Ventilators Market II-4 High Unmet Medical Needs Drive Developing Nations II-4 Developing Regions: Promising Markets for Infant/Neonatal Ventilation.............. II-5 Table 3: Global Population of Children between 0-4 years (2015P and 2020P) (includes corresponding Graph/Chart) II-6

Table 4: Population of Infants and Children (0-4 years) in Select Countries: 2013 (includes corresponding Graph/Chart) II-6 Non-Invasive Ventilators - The New Standard of Care II-7 Cost Benefits to Surge Growth of Non-Invasive Ventilators II-7 Neonatal Non-Invasive Ventilation - On the Rise II-7 HomeCare Ventilation Cuts Down on Rising Healthcare Costs II-8 Table 5: Healthcare Spending as % of GDP by Region (2016E) (includes corresponding Graph/Chart) II-8

Table 6: Worldwide Home Healthcare Services Market by Type of Service (2015and 2020P): Percentage Breakdown of Service Revenues for Infusion Therapy Services, Rehabilitation Services, Respiratory Therapy Services, Telemetry, and Unskilled Homecare (includes corresponding Graph/Chart) II-9 Increasing Popularity of Portable Ventilators II-9 Aging Population to Spur Demand for Mechanical Ventilators II-10 Table 7: 60+ Years Individuals as a Percentage of Total Population in Major Countries Worldwide: 2015, 2050, and 2100 (includes corresponding Graph/Chart) II-10 Competitive Landscape..............II-10 Table 8: Global Mechanical Ventilators Market by Leading Player (2015): Percentage Market Share Breakdown of Value Sales for Maquet (Getinge), Dräger Medical, Medtronic (Covidien), CareFusion/BD, and Others (includes corresponding Graph/Chart).............. II-11 Ways to Leverage Market Potential II-11 Key Market Challenges..............II-12

2. MARKET TRENDS, DRIVERS AND ISSUES II-13 Improved Patient Outcomes - The Force behind Mechanical Ventilator Innovations..............II-13 Automation-Enabled Innovation Continues in Mechanical Ventilators Market.............. II-14 The Changing Face of Ventilator Design II-15 Ventilator Associated Pneumonia (VAP): A Major Menace II-15 Innovations in Endotracheal Tube Design to Address VAP II-15 Manufacturers Introduce New Features to Tackle Enduring Issue of Alarm Fatigue.............. II-16 Advances in Information Technology Enhance Monitoring Multiple Patients on Ventilation..............II-17 Mechanical Ventilators Market Witnesses Increasing Patent Filings II-17 Table 9: Worldwide Mechanical Ventilators Patent Filings: 2008-2013 (includes corresponding Graph/Chart) II-18

Table 10: Mechanical Ventilator Patent Filings by Leading Companies (includes corresponding Graph/Chart) II-18 Emerging Markets Experience Low-Cost Ventilator Boom II-18 Non-Invasive Positive Pressure Ventilation (NIPPV) Market: Going Strong.............. II-19 Disposable Ventilator Masks to Record Strong Growth II-19 Western Markets Lead in Combined Ventilator Uptake II-19 H1N1: A Boon and Bane for Ventilator Market II-20 ECCO2R - An Ideal Replacement for Non-Invasive Ventilation Failure.............. II-20 High Potential for Automatic Transport Ventilators II-20 Neurally-Adjusted Ventilatory Assist (NAVA) - A Novel Ventilation Technique..............II-21 Respiratory Dialysis - An Alternative to Mechanical Ventilation? II-21 Adaptive Support Ventilation: At the Forefront of Innovation II-22

3. TECHNOLOGICAL INNOVATIONS..............II-23 Synchrony.............. II-23 INTELLiVENT-ASV Software of Hamilton Medical II-23 Dräger Medical's APRV AutoRelease II-23 Philips VentAssist.............. II-24 Medtronic PAV+ Plus Software..............II-24 Software for Reducing Leakage Amount II-24 Dräger Medical's Pressure Support Concept II-24 Hamilton Medical's Transport Ventilators with Advanced Modes II-24 Information Management..............II-25 New Alarm Systems.............. II-25 Automation.............. II-25 Simple User Interface..............II-26 Significance of Humidification in Mechanical Ventilation II-26

4. RESPIRATORY CONDITIONS REQUIRING MECHANICAL VENTILATORS: A REVIEW II-27 Acute Respiratory Distress Syndrome II-27 ARDS Fact Sheet.............. II-27 ARDS Treatment.............. II-27 Chronic Obstructive Pulmonary Disease II-28 Chronic Obstructive Pulmonary Disease (COPD) Fact Sheet: II-28 COPD Treatment.............. II-29 Muscular Degenerative Disease..............II-29 Spinal Cord Injury..............II-29 Spinal Cord Injury Treatment..............II-30 Pneumonia.............. II-30 Pneumonia Fact Sheet..............II-30 Cystic Fibrosis.............. II-30 Cystic Fibrosis Fact Sheet..............II-31 Cystic Fibrosis Treatment..............II-32 Asthma.............. II-32 Asthma Treatment.............. II-32

5. PRODUCT OVERVIEW.............. II-33 Lung Mechanics.............. II-33 Parameters Used in Monitoring Lung Mechanics II-34 Breathing Frequency..............II-34 Lung Volume and Airflow..............II-34 Airway and Esophageal Pressures II-34 Adequacy of Ventilation..............II-34 Mechanical Ventilator Segments II-35 Critical Care Ventilators..............II-35 Acute Care Ventilators..............II-35 Sub-acute Care Ventilators..............II-35 Neonatal Ventilators..............II-36 Conventional Neonatal Ventilators II-36 High Frequency Neonatal Ventilators II-36 Portable and Transport Ventilators II-37 The End-user Classification..............II-37 Modes of Ventilation..............II-38 Assist Control Ventilation..............II-38 Controlled Mechanical Ventilation II-38 Synchronized Intermittent Mandatory Ventilation II-38 Pressure Support Ventilation..............II-39 Adaptive Support Ventilation..............II-39 Continuous Positive Airway Pressure II-39 Positive End Expiratory Pressure II-39 Methods and Devices Used in Ventilatory Monitoring II-39 Impedance Pneumography..............II-39 Practical and Technical Considerations in Blood Gas Analysis II-40 Alarms.............. II-40 Inhalators.............. II-40 Optrode Technology.............. II-41 The History of Mechanical Ventilators II-41 Evolution of Mechanical Ventilators: A Historical Fact File II-41 The Development of Tank Respirator and the Cuirass Ventilator II-42 Tank Respirator.............. II-42 Cuirass Ventilator..............II-42 Conventional Mechanical Ventilation II-42

6. PRODUCT INTRODUCTIONS/APPROVALS II-44 Maquet Medical Systems Introduces Intensive Care and Neonatal Ventilators.............. II-44 Philips Launches Respironics V680 Ventilator II-44 Maquet Critical Care to Launch Turbine Ventilator SERVO-air II-44 Hamilton Medical Launches Pressure Controller for Mechanical Ventilators.............. II-44 GE Healthcare Launches Carescape R860 Ventilator with Simple Interface.............. II-44 Royal Philips Announces European Launch of V680 Ventilator II-44 OneBreath Reinvents Mechanical Ventilation II-45 SLE Introduces New Software for SLE4000 and SLE5000 Neonatal Ventilators.............. II-45 Hamilton Medical Offers HAMILTON-H900 with Intelligent Humidification.............. II-45 Hamilton Medical Unveils HAMILTON-T1 with Neonatal Option II-45 Covidien Receives FDA 510(k) Approval for Puritan Bennett™ 980 Ventilator.............. II-45 Covidien Receives CE Mark Approval for Puritan Bennett™ 980 Ventilator.............. II-45 Breas Medical Unveils Vivo 60 for Homecare Ventilation II-45 Smiths Medical Introduces Pneupac ParaPAC Plus in North America II-46 ResMed Launches Astral™ 100 and Astral™ 150 II-46 Dräger Showcases Novel Intensive Care Ventilator, Evita V300 II-46

7. RECENT INDUSTRY ACTIVITY..............II-47 FDA Designates CareFusion's Recall of AVEA Ventilator Units as Class I Recall.............. II-47 Becton, Dickinson and Company Acquires CareFusion II-47 CareFusion Signs Distribution Agreement with Breas Medical II-47 Medtronic Acquires Covidien..............II-47 ZOLL Medical Acquires Impact Instrumentation II-47 MAQUET and Swisstom Enter Into Distribution Partnership II-47 Breas Medical Takes Over BandD Electromedical, Ltd. II-48 Getinge Acquires CETREA..............II-48 PBM Capital Group Takes Over Breas II-48 Philips Respironics Recalls Trilogy Ventilators II-48 Philips Respironics Bags 3-Year Contract from US Department of HHS.............. II-48

8. FOCUS ON SELECT MAJOR PLAYERS..............II-49 CareFusion Corp. - A BD Company (US) II-49 Medtronic Plc. (Ireland)..............II-49 Dräger Medical, Inc. (US)..............II-50 Fisher and Paykel Healthcare Corp. Limited (New Zealand) II-50 GE Healthcare (UK)..............II-51 Breas Medical AB (Sweden)..............II-51 HAMILTON MEDICAL AG (Switzerland) II-52 MAQUET GmbH and Co. KG (Germany) II-52 Philips Respironics, Inc. (US) II-52 ResMed (US).............. II-53 Smiths Medical (UK).............. II-53

9. GLOBAL MARKET PERSPECTIVE..............II-54 Table 11: World Recent Past, Current and Future Analysis for Mechanical Ventilators by Geographic Region/Country - US, Canada, Japan, Europe, Asia-Pacific, Middle East and Africa, and Latin America Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart)..............II-54

Table 12: World Historic Review for Mechanical Ventilators by Geographic Region/Country - US, Canada, Japan, Europe, Asia-Pacific, Middle East and Africa, and Latin America Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart).............. II-55

Table 13: World 14-Year Perspective for Mechanical Ventilators by Geographic Region/Country - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific, Middle East and Africa, and Latin America Markets for Years 2009, 2016 and 2022 (includes corresponding Graph/Chart) II-56 Analytics by Segment..............II-57 Table 14: World Recent Past, Current and Future Analysis for Critical Care Ventilators by Geographic Region/Country - US, Canada, Japan, Europe, Asia-Pacific, Middle East and Africa, and Latin America Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart)..............II-57

Table 15: World Historic Review for Critical Care Ventilators by Geographic Region/Country - US, Canada, Japan, Europe, Asia-Pacific, Middle East and Africa, and Latin America Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart).............. II-58

Table 16: World 14-Year Perspective for Critical Care Ventilators by Geographic Region/Country - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific, Middle East and Africa, and Latin America Markets for Years 2009, 2016 and 2022 (includes corresponding Graph/Chart).............. II-59

Table 17: World Recent Past, Current and Future Analysis for Neonatal Ventilators by Geographic Region/Country - US, Canada, Japan, Europe, Asia-Pacific, Middle East and Africa, and Latin America Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart)..............II-60

Table 18: World Historic Review for Neonatal Ventilators by Geographic Region/ Country - US, Canada, Japan, Europe, Asia-Pacific, Middle East and Africa, and Latin America Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart).............. II-61

Table 19: World 14-Year Perspective for Neonatal Ventilators by Geographic Region/Country - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific, Middle East and Africa, and Latin America Markets for Years 2009, 2016 and 2022 (includes corresponding Graph/Chart) II-62

Table 20: World Recent Past, Current and Future Analysis for Portable and Transport Mechanical Ventilators by Geographic Region/Country - US, Canada, Japan, Europe, Asia-Pacific, Middle East and Africa, and Latin America Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart) II-63

Table 21: World Historic Review for Portable and Transport Mechanical Ventilators by Geographic Region/ Country - US, Canada, Japan, Europe, Asia-Pacific, Middle East and Africa, and Latin America Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart)..............II-64

Table 22: World 14-Year Perspective for Portable and Transport Mechanical Ventilators by Geographic Region/Country - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific, Middle East and Africa, and Latin America Markets for Years 2009, 2016 and 2022 (includes corresponding Graph/Chart).............. II-65

III. MARKET

1. THE UNITED STATES.............. III-1 A.Market Analysis.............. III-1 Current and Future Analysis..............III-1 Increasing Respiratory Disorders Drive Demand for Mechanical Ventilators.............. III-1 Table 23: COPD Associated Fatality Rate in the US by Gender (In %): 1999-2010 (includes corresponding Graph/Chart) III-2

Table 24: Chronic Bronchitis Prevalence in the US by Age Group (In Percentage per 1000 Population): 2011 for Ages 18-44, 45-64, and 65+ years (includes corresponding Graph/Chart).............. III-2

Table 25: Emphysema Prevalence in the US by Age Group (In Percentage per 1000 Population): 2011 for Ages 18-44, 45-64 and 65+ years (includes corresponding Graph/Chart) III-3

Table 26: COPD Prevalence In the US by State (In Percentage): 2011 statistics for Kentucky, Alabama, Tennessee, West Virginia, Mississippi, Oklahoma, Indiana, Michigan, Arkansas, and Florida (includes corresponding Graph/Chart).............. III-3 Aging Demographics Increase the Need for Ventilation III-4 Table 27: North American Elderly Population by Age Group: 1975-2050 (includes corresponding Graph/Chart) III-4 Technology Driving Ventilator Design, Features, etc III-4 Regulations - A Major Factor Influencing the Mechanical Ventilators Market..............III-5 Reimbursements for Ventilation III-5 Table 28: Medicare Reimbursement for Portable Ventilators: 2014.............. III-6 Product Launches..............III-7 Strategic Corporate Developments III-8 Select Key Players..............III-9 B.Market Analytics..............III-13 Table 29: The US Recent Past, Current and Future Analysis for Mechanical Ventilators by Product Segment - Critical Care, Neonatal, and Portable and Transport Ventilators Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart) III-13

Table 30: The US Historic Review for Mechanical Ventilators by Product Segment - Critical Care, Neonatal, and Portable and Transport Ventilators Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart) III-14

Table 31: The US 14-Year Perspective for Mechanical Ventilators by Product Segment - Percentage Breakdown of Dollar Sales for Critical Care, Neonatal, and Portable and Transport Ventilators for Years 2009, 2016 and 2022 (includes corresponding Graph/Chart) III-15

2. CANADA.............. III-16 A.Market Analysis.............. III-16 Product Launch.............. III-16 B.Market Analytics..............III-17 Table 32: Canadian Recent Past, Current and Future Analysis for Mechanical Ventilators by Product Segment - Critical Care, Neonatal, and Portable and Transport Ventilators Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart).............. III-17

Table 33: Canadian Historic Review for Mechanical Ventilators by Product Segment - Critical Care, Neonatal, and Portable and Transport Ventilators Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart) III-18

Table 34: Canadian 14-Year Perspective for Mechanical Ventilators by Product Segment - Percentage Breakdown of Dollar Sales for Critical Care, Neonatal, and Portable and Transport Ventilators for Years 2009, 2016 and 2022 (includes corresponding Graph/Chart) III-19

3. JAPAN.............. III-20 A.Market Analysis.............. III-20 Graying Population Spurs Growth of Mechanical Ventilators III-20 Table 35: Japanese Elderly (65+ Years) Population: 2000-2020 (includes corresponding Graph/Chart) III-20 Acoma Medical Industry Co., Ltd. - A Key Regional Player III-20 B.Market Analytics..............III-21 Table 36: Japanese Recent Past, Current and Future Analysis for Mechanical Ventilators by Product Segment - Critical Care, Neonatal, and Portable and Transport Ventilators Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart).............. III-21

Table 37: Japanese Historic Review for Mechanical Ventilators by Product Segment - Critical Care, Neonatal, and Portable and Transport Ventilators Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart) III-22

Table 38: Japanese 14-Year Perspective for Mechanical Ventilators by Product Segment - Percentage Breakdown of Dollar Sales for Critical Care, Neonatal, and Portable and Transport Ventilators for Years 2009, 2016 and 2022 (includes corresponding Graph/Chart) III-23

4. EUROPE.............. III-24 A.Market Analysis.............. III-24 Current and Future Market Perspective III-24 Ageing Demography - An Opportunity Indicator III-24 Table 39: European Country-wise Statistics of 60+ Population as % of Total Population: 2013 (includes corresponding Graph/Chart)..............III-25 Increasing Online Sales of Non-Invasive Ventilators III-26 Product Launches..............III-26 B.Market Analytics..............III-27 Table 40: European Recent Past, Current and Future Analysis for Mechanical Ventilators by Geographic Region/Country - France, Germany, Italy, UK, Spain, Russia and Rest of Europe Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart)..............III-27

Table 41: European Historic Review for Mechanical Ventilators by Geographic Region/Country - France, Germany, Italy, UK, Spain, Russia and Rest of Europe Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart).............. III-28

Table 42: European 14-Year Perspective for Mechanical Ventilators by Geographic Region/ Country - Percentage Breakdown of Dollar Sales for France, Germany, Italy, UK, Spain, Russia and Rest of Europe Markets for Years 2009, 2016 and 2022 (includes corresponding Graph/Chart) III-29

Table 43: European Recent Past, Current and Future Analysis for Mechanical Ventilators by Product Segment - Critical Care, Neonatal, and Portable and Transport Ventilators Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart).............. III-30

Table 44: European Historic Review for Mechanical Ventilators by Product Segment - Critical Care, Neonatal, and Portable and Transport Ventilators Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart) III-31

Table 45: European 14-Year Perspective for Mechanical Ventilators by Product Segment - Percentage Breakdown of Dollar Sales for Critical Care, Neonatal, and Portable and Transport Ventilators for Years 2009, 2016 and 2022 (includes corresponding Graph/Chart) III-32

4a. FRANCE.............. III-33 Market Analysis.............. III-33 Table 46: French Recent Past, Current and Future Analysis for Mechanical Ventilators by Product Segment - Critical Care, Neonatal, and Portable and Transport Ventilators Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart) III-33

Table 47: French Historic Review for Mechanical Ventilators by Product Segment - Critical Care, Neonatal, and Portable and Transport Ventilators Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart) III-34

Table 48: French 14-Year Perspective for Mechanical Ventilators by Product Segment - Percentage Breakdown of Dollar Sales for Critical Care, Neonatal, and Portable and Transport Ventilators for Years 2009, 2016 and 2022 (includes corresponding Graph/Chart) III-35

4b. GERMANY.............. III-36 A.Market Analysis.............. III-36 Product Launch.............. III-36 Select Key Players..............III-36 B.Market Analytics..............III-37 Table 49: German Recent Past, Current and Future Analysis for Mechanical Ventilators by Product Segment - Critical Care, Neonatal, and Portable and Transport Ventilators Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart) III-37

Table 50: German Historic Review for Mechanical Ventilators by Product Segment - Critical Care, Neonatal, and Portable and Transport Ventilators Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart) III-38

Table 51: German 14-Year Perspective for Mechanical Ventilators by Product Segment - Percentage Breakdown of Dollar Sales for Critical Care, Neonatal, and Portable and Transport Ventilators for Years 2009, 2016 and 2022 (includes corresponding Graph/Chart) III-39

4c. ITALY.............. III-40 A.Market Analysis.............. III-40 Dima Italia S.R.L. - A Key Italian Player III-40 B.Market Analytics..............III-41 Table 52: Italian Recent Past, Current and Future Analysis for Mechanical Ventilators by Product Segment - Critical Care, Neonatal, and Portable and Transport Ventilators Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart) III-41

Table 53: Italian Historic Review for Mechanical Ventilators by Product Segment - Critical Care, Neonatal, and Portable and Transport Ventilators Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart) III-42

Table 54: Italian 14-Year Perspective for Mechanical Ventilators by Product Segment - Percentage Breakdown of Dollar Sales for Critical Care, Neonatal, and Portable and Transport Ventilators for Years 2009, 2016 and 2022 (includes corresponding Graph/Chart) III-43

4d. THE UNITED KINGDOM..............III-44 A.Market Analysis.............. III-44 Product Launch.............. III-44 Strategic Corporate Development III-44 Select Key Players..............III-44 B.Market Analytics..............III-47 Table 55: The UK Recent Past, Current and Future Analysis for Mechanical Ventilators by Product Segment - Critical Care, Neonatal, and Portable and Transport Ventilators Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart) III-47

Table 56: The UK Historic Review for Mechanical Ventilators by Product Segment - Critical Care, Neonatal, and Portable and Transport Ventilators Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart) III-48

Table 57: The UK 14-Year Perspective for Mechanical Ventilators by Product Segment - Percentage Breakdown of Dollar Sales for Critical Care, Neonatal, and Portable and Transport Ventilators for Years 2009, 2016 and 2022 (includes corresponding Graph/Chart) III-49

4e. SPAIN.............. III-50 Market Analysis.............. III-50 Table 58: Spanish Recent Past, Current and Future Analysis for Mechanical Ventilators by Product Segment - Critical Care, Neonatal, and Portable and Transport Ventilators Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart) III-50

Table 59: Spanish Historic Review for Mechanical Ventilators by Product Segment - Critical Care, Neonatal, and Portable and Transport Ventilators Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart) III-51

Table 60: Spanish 14-Year Perspective for Mechanical Ventilators by Product Segment - Percentage Breakdown of Dollar Sales for Critical Care, Neonatal, and Portable and Transport Ventilators for Years 2009, 2016 and 2022 (includes corresponding Graph/Chart) III-52

4f. RUSSIA.............. III-53 Market Analysis.............. III-53 Table 61: Russian Recent Past, Current and Future Analysis for Mechanical Ventilators by Product Segment - Critical Care, Neonatal, and Portable and Transport Ventilators Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart) III-53

Table 62: Russian Historic Review for Mechanical Ventilators by Product Segment - Critical Care, Neonatal, and Portable and Transport Ventilators Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart) III-54

Table 63: Russian 14-Year Perspective for Mechanical Ventilators by Product Segment - Percentage Breakdown of Dollar Sales for Critical Care, Neonatal, and Portable and Transport Ventilators for Years 2009, 2016 and 2022 (includes corresponding Graph/Chart) III-55

4g. REST OF EUROPE.............. III-56 A.Market Analysis.............. III-56 Competitive Landscape..............III-56 Table 64: East European Mechanical Ventilators Market by Leading Player (2015): Percentage Market Share Breakdown of Value Sales for Medtronic, Drägerwerk AG and Co. KGaA, GE Healthcare, and Others (includes corresponding Graph/Chart) III-56 Poland - A Growing Market..............III-57 Product Launches..............III-57 Strategic Corporate Developments III-57 Select Key Players..............III-58 B.Market Analytics..............III-60 Table 65: Rest of European Recent Past, Current and Future Analysis for Mechanical Ventilators by Product Segment - Critical Care, Neonatal, and Portable and Transport Ventilators Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart)..............III-60

Table 66: Rest of European Historic Review for Mechanical Ventilators by Product Segment - Critical Care, Neonatal, and Portable and Transport Ventilators Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart) III-61

Table 67: Rest of European 14-Year Perspective for Mechanical Ventilators by Product Segment - Percentage Breakdown of Dollar Sales for Critical Care, Neonatal, and Portable and Transport Ventilators for Years 2009, 2016 and 2022 (includes corresponding Graph/Chart) III-62

5. ASIA-PACIFIC.............. III-63 A.Market Analysis.............. III-63 Current and Future Analysis..............III-63 Aging Populace - Potential Opportunities III-63 Table 68: Over 65 Years Individuals as % of the Total Population in Select Asian Countries (includes corresponding Graph/Chart)..............III-63 Healthcare Spending on the Rise III-64 India and China Offer Significant Growth Opportunities III-64 Table 69: Age-wise Breakup of China and India's Population: As of July 2013 (includes corresponding Graph/Chart) III-65 An Insight into the Asia-Pacific Healthcare Sector III-65 B.Market Analytics..............III-66 Table 70: Asia-Pacific Recent Past, Current and Future Analysis for Mechanical Ventilators by Geographic Region/Country - China, India and Rest of Asia-Pacific Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart)..............III-66

Table 71: Asia-Pacific Historic Review for Mechanical Ventilators by Geographic Region/ Country - China, India and Rest of Asia-Pacific Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart) III-67

Table 72: Asia-Pacific 14-Year Perspective for Mechanical Ventilators by Geographic Region/ Country - Percentage Breakdown of Dollar Sales for China, India and Rest of Asia-Pacific Markets for Years 2009, 2016 and 2022 (includes corresponding Graph/Chart)..............III-68

Table 73: Asia-Pacific Recent Past, Current and Future Analysis for Mechanical Ventilators by Product Segment - Critical Care, Neonatal, and Portable and Transport Ventilators Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart)..............III-69

Table 74: Asia-Pacific Historic Review for Mechanical Ventilators by Product Segment - Critical Care, Neonatal, and Portable and Transport Ventilators Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart) III-70

Table 75: Asia-Pacific 14-Year Perspective for Mechanical Ventilators by Product Segment - Percentage Breakdown of Dollar Sales for Critical Care, Neonatal, and Portable and Transport Ventilators for Years 2009, 2016 and 2022 (includes corresponding Graph/Chart) III-71

5a. CHINA.............. III-72 A.Market Analysis.............. III-72 Current and Future Analysis..............III-72 Increasing Expenditure on Healthcare Sector III-72 Mindray Medical International Ltd. - A Key Player III-72 B.Market Analytics..............III-73 Table 76: Chinese Recent Past, Current and Future Analysis for Mechanical Ventilators by Product Segment - Critical Care, Neonatal, and Portable and Transport Ventilators Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart) III-73

Table 77: Chinese Historic Review for Mechanical Ventilators by Product Segment - Critical Care, Neonatal, and Portable and Transport Ventilators Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart) III-74

Table 78: Chinese 14-Year Perspective for Mechanical Ventilators by Product Segment - Percentage Breakdown of Dollar Sales for Critical Care, Neonatal, and Portable and Transport Ventilators for Years 2009, 2016 and 2022 (includes corresponding Graph/Chart) III-75

5b. INDIA.............. III-76 A.Market Analysis.............. III-76 A High Potential Market..............III-76 Indian Ventilators Market - An Overview III-76 Indian Ventilator Market to Witness Steady Growth in Future III-76 After-Sales Services and Cost Considerations Significant III-77 Non-Invasive Ventilation: The Preferred Choice III-77 Neonatal Ventilators Market Exhibits Bright Prospects III-78 B.Market Analytics..............III-79 Table 79: Indian Recent Past, Current and Future Analysis for Mechanical Ventilators by Product Segment - Critical Care, Neonatal, and Portable and Transport Ventilators Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart) III-79

Table 80: Indian Historic Review for Mechanical Ventilators by Product Segment - Critical Care, Neonatal, and Portable and Transport Ventilators Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart) III-80

Table 81: Indian 14-Year Perspective for Mechanical Ventilators by Product Segment - Percentage Breakdown of Dollar Sales for Critical Care, Neonatal, and Portable and Transport Ventilators for Years 2009, 2016 and 2022 (includes corresponding Graph/Chart) III-81

5c. REST OF ASIA-PACIFIC..............III-82 A.Market Analysis.............. III-82 Product Launch.............. III-82 Fisher and Paykel Healthcare Corp. Limited - Key New Zealand- Based Player.............. III-82 B.Market Analytics..............III-83 Table 82: Rest of Asia-Pacific Recent Past, Current and Future Analysis for Mechanical Ventilators by Product Segment - Critical Care, Neonatal, and Portable and Transport Ventilators Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart)..............III-83

Table 83: Rest of Asia-Pacific Historic Review for Mechanical Ventilators by Product Segment - Critical Care, Neonatal, and Portable and Transport Ventilators Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart) III-84

Table 84: Rest of Asia-Pacific 14-Year Perspective for Mechanical Ventilators by Product Segment - Percentage Breakdown of Dollar Sales for Critical Care, Neonatal, and Portable and Transport Ventilators for Years 2009, 2016 and 2022 (includes corresponding Graph/Chart) III-85

6. THE MIDDLE EAST and AFRICA..............III-86 A.Market Analysis.............. III-86 Product Launch.............. III-86 B.Market Analytics..............III-87 Table 85: The Middle East and Africa Recent Past, Current and Future Analysis for Mechanical Ventilators by Product Segment - Critical Care, Neonatal, and Portable and Transport Ventilators Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart)..............III-87

Table 86: The Middle East and Africa Historic Review for Mechanical Ventilators by Product Segment - Critical Care, Neonatal, and Portable and Transport Ventilators Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart) III-88

Table 87: The Middle East and Africa 14-Year Perspective for Mechanical Ventilators by Product Segment - Percentage Breakdown of Dollar Sales for Critical Care, Neonatal, and Portable and Transport Ventilators for Years 2009, 2016 and 2022 (includes corresponding Graph/Chart) III-89

7. LATIN AMERICA.............. III-90 Market Analysis.............. III-90 Table 88: Latin American Recent Past, Current and Future Analysis for Mechanical Ventilators by Geographic Region/Country - Brazil and Rest of Latin America Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart).............. III-90

Table 89: Latin American Historic Review for Mechanical Ventilators by Geographic Region/ Country - Brazil and Rest of Latin America Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart) III-91

Table 90: Latin American 14-Year Perspective for Mechanical Ventilators by Geographic Region/ Country - Percentage Breakdown of Dollar Sales for Brazil and Rest of Latin America Markets for Years 2009, 2016 and 2022 (includes corresponding Graph/Chart)..............III-92

Table 91: Latin American Recent Past, Current and Future Analysis for Mechanical Ventilators by Product Segment - Critical Care, Neonatal, and Portable and Transport Ventilators Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart)..............III-93

Table 92: Latin American Historic Review for Mechanical Ventilators by Product Segment - Critical Care, Neonatal, and Portable and Transport Ventilators Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart) III-94

Table 93: Latin American 14-Year Perspective for Mechanical Ventilators by Product Segment - Percentage Breakdown of Dollar Sales for Critical Care, Neonatal, and Portable and Transport Ventilators for Years 2009, 2016 and 2022 (includes corresponding Graph/Chart) III-95

7a. BRAZIL.............. III-96 Market Analysis.............. III-96 Table 94: Brazilian Recent Past, Current and Future Analysis for Mechanical Ventilators by Product Segment - Critical Care, Neonatal, and Portable and Transport Ventilators Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart).............. III-96

Table 95: Brazilian Historic Review for Mechanical Ventilators by Product Segment - Critical Care, Neonatal, and Portable and Transport Ventilators Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart) III-97

Table 96: Brazilian 14-Year Perspective for Mechanical Ventilators by Product Segment - Percentage Breakdown of Dollar Sales for Critical Care, Neonatal, and Portable and Transport Ventilators for Years 2009, 2016 and 2022 (includes corresponding Graph/Chart) III-98

7b. REST OF LATIN AMERICA..............III-99 Market Analysis.............. III-99 Table 97: Rest of Latin American Recent Past, Current and Future Analysis for Mechanical Ventilators by Product Segment - Critical Care, Neonatal, and Portable and Transport Ventilators Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart)..............III-99

Table 98: Rest of Latin American Historic Review for Mechanical Ventilators by Product Segment - Critical Care, Neonatal, and Portable and Transport Ventilators Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart) III-100

Table 99: Rest of Latin American 14-Year Perspective for Mechanical Ventilators by Product Segment - Percentage Breakdown of Dollar Sales for Critical Care, Neonatal, and Portable and Transport Ventilators for Years 2009, 2016 and 2022 (includes corresponding Graph/Chart) III-101

IV. COMPETITIVE LANDSCAPE

Total Companies Profiled: 61 (including Divisions/Subsidiaries - 67)

The United States (21) Canada (1) Japan (1) Europe (25) - France (1) - Germany (8) - The United Kingdom (5) - Italy (3) - Rest of Europe (8) Asia-Pacific (Excluding Japan) (17) Latin America (2)

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