Skin Disease Treatment Technologies and Global Markets

  • May 2013
  • -
  • BCC Research
  • -
  • 130 pages

INTRODUCTION

STUDY GOALS AND OBJECTIVES

The aim of this report is to provide detailed market, technology and industry analyses to help readers quantify and qualify the market for drugs used in the treatment of the major skin diseases. Special emphasis is given to ongoing research into improved treatment modalities, especially those utilizing biological approaches. Important trends are identified and sales forecasts by product categories and major country markets are provided through 2018; these are based on epidemiological data and projections plus information on R&D trends and their likely effects on market potential on a country-by-country basis.

REASONS FOR DOING THE STUDY

The dermatology market is facing a period of change after several years during which it was a relatively modest and slow-growing sector within the overall pharmaceutical environment. The advent of innovative therapies for some skin diseases has been a stimulus for renewed interest in this market among major pharma companies. New contenders in this market have emerged as small to medium-size companies evolve into medium to large concerns by a process of serial acquisitions. In this environment there is a need for an up-to-date and comprehensive appraisal of the dermatology marketplace, with a review of the most important diseases, portfolios and pipelines.

SCOPE OF REPORT

This report discusses the implications of the above-mentioned trends in the context of the current size and growth of the dermatology market, discussed both in global terms and in reference to the most important national markets. Long-standing and emerging companies are discussed, with profiles of their leaders and an update on M&A activity. Five-year global sales forecasts are provided for main drug categories, and breakdowns are provided for several national markets.

MARKET ANALYSES AND FORECASTS

Market figures are based on revenues at the manufacturer level and are projected at 2012 dollar value without an attempt to predict the effect of inflation/deflation. Therapeutic categories discussed include dermatitis, psoriasis, acne, lupus, skin infections (bacterial, fungal, viral) and skin cancers.

METHODOLOGY

Primary research includes interviews with leading individuals in relevant companies and medical associations; primary sources of published data include epidemiological and economic studies, company annual reports, SEC filings and government publications. Secondary sources consist of literature searches, industry journals and other commercial publications. Data for market estimates and forecasts are pooled from a range of sources and are critically assessed by BCC. In this report, “global” is defined as the sum of the following national markets: U.S., Japan, the leading five EU markets (Germany, France, Italy, Spain and U.K., abbreviated to EU5) and the four BRIC countries: Brazil, Russia, India and China. The rest of the world is thought to represent not much more than 10% of the actual global total, and there are few or no data for most of the countries that contribute to this segment, so we have left them out of the discussion.

INTENDED AUDIENCE

This report is designed to satisfy the information needs of a wide variety of individuals involved in the dermatology marketplace, including company senior management executives seeking to base their strategic decisions on the best available information on market forces and trends. However, it is also aimed at managers and executives in marketing, research, planning and sales departments who need readable, comprehensive and up-to-date background on the marketplace in which they are operating.

INFORMATION SOURCES

Sources of information included marketing strategists, industry executives, government and professional agencies and surveys of physicians. Company annual reports and SEC filings, journal articles and data from healthcare institutions were also mined.

ANALYST CREDENTIALS

Paul Evers has been involved in analyzing pharmaceutical and medical markets for 20 years. He is the author of several previous BCC reports on diseases affecting different organ systems in addition to the skin.

Table Of Contents

TABLE OF CONTENTS

CHAPTER 1 INTRODUCTION 2
STUDY GOALS AND OBJECTIVES 2
REASONS FOR DOING THE STUDY 2
SCOPE OF REPORT 2
MARKET ANALYSES AND FORECASTS 2
METHODOLOGY 2
INTENDED AUDIENCE 3
INFORMATION SOURCES 3
ANALYST CREDENTIALS 3
RELATED BCC REPORTS 3
BCC ONLINE SERVICES 3
DISCLAIMER 4
CHAPTER 2 SUMMARY 6
SKIN DISEASE AND ITS TREATMENT 6
DISEASES INCLUDED 6
TREATMENTS 6
SUMMARY TABLE 1 DERMATOLOGICAL AGENTS 7
ABOUT THE MARKET 7
LEADING COMPANIES 8
SUMMARY TABLE 2 MAJOR GLOBAL DERMATOLOGY MARKETS, THROUGH 2018 ($
MILLIONS) 8
SUMMARY FIGURE MAJOR GLOBAL DERMATOLOGY MARKETS, 2011-2018 ($
MILLIONS) 8
CHAPTER 3 OVERVIEW 11
SKIN STRUCTURE AND FUNCTIONS 11
STRUCTURE 11
Epidermis 11
Basement Membrane 12
Dermis 12
Hypodermis 12
FUNCTIONS 12
DISEASES OF THE SKIN 13
TABLE 1 PREVALENCE AND DIRECT COSTS OF SELECTED SKIN DISEASES, U.S.,
2004 (MILLIONS) 13
CHAPTER 4 MAJOR SKIN DISEASES 15
DERMATITIS 15
SEBORRHEIC DERMATITIS 15
Available Treatments 15
ATOPIC DERMATITIS 15
Available Treatments 16
CONTACT DERMATITIS 16
Available Treatments 17
Irritant Contact Dermatitis 17
Allergic Contact Dermatitis 17
DERMATITIS PIPELINE 18
TABLE 2 DERMATITIS RESEARCH PIPELINE 18
TABLE 3 GLOBAL DERMATITIS MARKET, THROUGH 2018 ($ MILLIONS) 19
IMMUNE-RELATED CONDITIONS 20
LUPUS ERYTHEMATOSUS 20
CURRENT TREATMENT OPTIONS 21
PIPELINE 21
TABLE 4 CUTANEOUS LUPUS PIPELINE 21
IMMUNO-BULLOUS DISEASES 22
Treatment Options 22
Market 22
TABLE 5 GLOBAL MARKET FOR IMMUNE-RELATED SKIN CONDITIONS, THROUGH
2018 ($ MILLIONS) 23
LICHEN PLANUS 23
Current Treatment Options 23
ERYTHEMA MULTIFORME 24
Treatments Available 24
PSORIASIS 25
SUBTYPES 25
Plaque Psoriasis 25
Guttate Psoriasis 25
Erythrodermic Psoriasis 26
Pustular Psoriasis 26
Psoriasis of the Nails 26
TREATMENT 26
Topical Therapies Available 26
Emollients 26
Keratolytics 26
Topical Corticosteroids 27
Vitamin D3 Products 27
Tazarotene 27
Tar Preparations 27
Anthralin 27
Topical Immunomodulators 28
Intralesional Therapy 28
Phototherapy with UVB 28
Photochemotherapy (PUVA) 28
Systemic Therapy 28
Methotrexate 28
Acitretin 28
Cyclosporine 29
Hydroxyurea 29
Cytokine Antagonists and Other Immunomodulators 29
PSORIASIS TREATMENT BENEFITS AND RISKS 29
Cost of Treatment 31
TABLE 6 COST OF PSORIASIS THERAPIES FOR A TYPICAL WESTERN EUROPEAN
COUNTRY ($) 31
THE PSORIASIS PIPELINE 32
THE PSORIASIS MARKET 34
TABLE 7 PSORIASIS GLOBAL AND REGIONAL MARKET, THROUGH 2018 ($ MILLIONS) 35
SKIN INFECTIONS 35
BACTERIAL INFECTIONS 35
Impetigo/Ecthyma 36
Cellulitis 36
Treatments Available 37
Necrotizing Subcutaneous Infection 38
Available Treatment 38
FUNGAL INFECTIONS 38
Candidiasis 38
Treatments Available 39
TABLE 8 ANTIFUNGALS FOR SUPERFICIAL FUNGAL INFECTIONS 40
Tinea Versicolor 40
Treatments Available 40
VIRAL INFECTIONS 41
Herpes Simplex 41
Treatments Available 42
Herpes Zoster 42
Warts 42
TABLE 9 ANTIVIRAL DRUGS 43
SKIN INFECTION PIPELINE 44
TABLE 10 SKIN INFECTIONS PIPELINE 44
THE ANTI-INFECTIVE MARKET 47
TABLE 11 SKIN INFECTIONS: GLOBAL MARKET, THROUGH 2018 ($ MILLIONS) 47
ACNE 47
Comedonal 48
Papulopustular 48
Nodulocystic 48
Treatments Available 49
Retinoids 49
Antibiotics 49
Anti-Inflammatory Drugs 50
Hormonal Therapy 50
Treatment Failure 51
THE ACNE PIPELINE 51
TABLE 12 THE ACNE PRODUCT PIPELINE 51
THE ACNE MARKET 52
TABLE 13 GLOBAL ACNE MEDICATIONS MARKET, THROUGH 2018 ($ MILLIONS) 53
SKIN CANCERS 53
MELANOMA 53
Treatment 54
NONMELANOMA SKIN CANCERS 54
Basal Cell Carcinoma 54
Squamous Cell Carcinoma 55
SKIN CANCER PIPELINE 55
TABLE 14 SKIN CANCER THERAPEUTICS RESEARCH PIPELINE 56
SKIN CANCER MARKET 59
TABLE 15 SKIN CANCER THERAPEUTIC MARKET, THROUGH 2018 ($ MILLIONS) 59
CHAPTER 5 DERMATOLOGY PRODUCTS, BY BRAND NAME 61
ALDARA 61
ALTABAX 61
AMEVIVE 62
AVITA GEL 62
BACTROBAN CREAM 62
BENZAMYCIN 62
BETNOVATE 63
DALACIN 63
CONDYLOX 63
DAIVOBET 64
DESONATE 64
DIFFERIN 64
ELIDEL 65
ELOCON 65
ERIVEDGE 65
ESTROSTEP FE 66
EXTINA 66
FINACEA 66
FINEVIN 67
GRALISE 67
HORIZANT 67
KLARON 68
LAMISIL 68
MEDROL 68
TRI-CYCLEN 69
PROGRAF 69
PROTOPIC 69
RETIN-A MICRO 70
SOLODYN 70
STELARA 70
SYLATRON 71
TACLONEX 71
TAZORAC 71
TEFLARO 72
TYGACIL 72
VELTINGEL 72
VERDESO 73
VIBATIV 73
VIBRAMYCIN 73
YERVOY 74
ZELBORAF 74
ZOVIRAX 74
ZYCLARA 75
CHAPTER 6 CURRENT AND FORECAST MARKETS 77
DEVELOPED MARKETS 77
U.S. 77
TABLE 16 U.S. ANNUAL DIRECT COST OF PRESCRIPTION DRUGS, 2004 ($ MILLIONS) 78
TABLE 17 THE DERMATOLOGY MARKET IN THE U.S. THROUGH 2018 ($ MILLIONS/%) 78
JAPAN 79
TABLE 18 THE DERMATOLOGY MARKET IN JAPAN, THROUGH 2018 ($ MILLIONS/%) 79
GERMANY 79
TABLE 19 THE DERMATOLOGY MARKET IN GERMANY, THROUGH 2018 ($
MILLIONS/%) 80
FRANCE 80
TABLE 20 THE DERMATOLOGY MARKET IN FRANCE, THROUGH 2018 ($ MILLIONS/%) 81
ITALY 81
TABLE 21 THE DERMATOLOGY MARKET IN ITALY, THROUGH 2018 ($ MILLIONS/%) 82
SPAIN 82
TABLE 22 THE DERMATOLOGY MARKET IN SPAIN, THROUGH 2018 ($ MILLIONS) 83
UNITED KINGDOM 83
TABLE 23 THE DERMATOLOGY MARKET IN THE UNITED KINGDOM, THROUGH 2018
($ MILLIONS/%) 85
BRIC MARKETS 85
BRAZIL 85
TABLE 24 THE DERMATOLOGY MARKET IN BRAZIL, THROUGH 2018 ($ MILLIONS/%) 86
RUSSIA 86
TABLE 25 THE DERMATOLOGY MARKET IN RUSSIA, THROUGH 2018 ($ MILLIONS/%) 88
INDIA 88
TABLE 26 THE DERMATOLOGY MARKET IN INDIA, THROUGH 2018 ($ MILLIONS/%) 88
CHINA 89
TABLE 27 HEALTHCARE STATISTICS IN CHINA 2006 VERSUS 2011 ($ BILLIONS/%) 89
TABLE 28 THE DERMATOLOGY MARKET IN CHINA, THROUGH 2018 ($ MILLIONS/%) 90
CHAPTER 7 THE DERMATOLOGY INDUSTRY 92
INDUSTRY STRUCTURE AND TRENDS 92
COMPANY PROFILES 94
ABBVIE 94
AGENUS 94
AICURIS 95
ALLERGAN 96
ALMIRALL 97
AMGEN 98
ANACOR 98
ANGES MG 99
APEIRON 100
ASTELLAS 101
ASTION 101
ASTRAZENECA 103
BARRIER THERAPEUTICS 104
BASILEA 104
BRISTOL-MYERS SQUIBB 105
CELGENE 105
CIPHER PHARMACEUTICALS 106
DUSA 107
BLU-U 107
ELI LILLY 107
GALDERMA 108
GENENTECH 109
GLAXOSMITHKLINE 110
STIEFEL, A GSK COMPANY 110
The Center for Skin Biology 110
HANALL BIOPHARMA 111
IMMUNE TECHNOLOGIES and MEDICINE 111
INCYTE 112
JANSSEN BIOTECH 113
KAKEN PHARMACEUTICALS 114
LEO 115
MEDA 116
NANOBIO 117
NAVIDEA 119
NITRIC BIOTHERAPEUTICS 120
NOVARTIS 120
PFIZER 121
PHOTOCURE 122
REGENERON 123
SWITCH BIOTECH 124
VALEANT 124
CHAPTER 8 APPENDIX I: GLOSSARY 127
CHAPTER 9 APPENDIX II: THE IMMUNE SYSTEM 134
TABLE 29 IMMUNOTHERAPEUTICS IN SKIN DISEASES 138

LIST OF TABLES
SUMMARY TABLE 1 DERMATOLOGICAL AGENTS 7
SUMMARY TABLE 2 MAJOR GLOBAL DERMATOLOGY MARKETS, THROUGH 2018 ($
MILLIONS) 8
TABLE 1 PREVALENCE AND DIRECT COSTS OF SELECTED SKIN DISEASES, U.S., 2004
(MILLIONS) 13
TABLE 2 DERMATITIS RESEARCH PIPELINE 18
TABLE 3 GLOBAL DERMATITIS MARKET, THROUGH 2018 ($ MILLIONS) 19
TABLE 4 CUTANEOUS LUPUS PIPELINE 21
TABLE 5 GLOBAL MARKET FOR IMMUNE-RELATED SKIN CONDITIONS, THROUGH
2018 ($ MILLIONS) 23
TABLE 6 COST OF PSORIASIS THERAPIES FOR A TYPICAL WESTERN EUROPEAN
COUNTRY ($) 31
TABLE 7 PSORIASIS GLOBAL AND REGIONAL MARKET, THROUGH 2018 ($ MILLIONS) 35
TABLE 8 ANTIFUNGALS FOR SUPERFICIAL FUNGAL INFECTIONS 40
TABLE 9 ANTIVIRAL DRUGS 43
TABLE 10 SKIN INFECTIONS PIPELINE 44
TABLE 11 SKIN INFECTIONS: GLOBAL MARKET, THROUGH 2018 ($ MILLIONS) 47
TABLE 12 THE ACNE PRODUCT PIPELINE 51
TABLE 13 GLOBAL ACNE MEDICATIONS MARKET, THROUGH 2018 ($ MILLIONS) 53
TABLE 14 SKIN CANCER THERAPEUTICS RESEARCH PIPELINE 56
TABLE 15 SKIN CANCER THERAPEUTIC MARKET, THROUGH 2018 ($ MILLIONS) 59
TABLE 16 U.S. ANNUAL DIRECT COST OF PRESCRIPTION DRUGS, 2004 ($ MILLIONS) 78
TABLE 17 THE DERMATOLOGY MARKET IN THE U.S. THROUGH 2018 ($ MILLIONS/%) 78
TABLE 18 THE DERMATOLOGY MARKET IN JAPAN, THROUGH 2018 ($ MILLIONS/%) 79
TABLE 19 THE DERMATOLOGY MARKET IN GERMANY, THROUGH 2018 ($
MILLIONS/%) 80
TABLE 20 THE DERMATOLOGY MARKET IN FRANCE, THROUGH 2018 ($ MILLIONS/%) 81
TABLE 21 THE DERMATOLOGY MARKET IN ITALY, THROUGH 2018 ($ MILLIONS/%) 82
TABLE 22 THE DERMATOLOGY MARKET IN SPAIN, THROUGH 2018 ($ MILLIONS) 83
TABLE 23 THE DERMATOLOGY MARKET IN THE UNITED KINGDOM, THROUGH 2018
($ MILLIONS/%) 85
TABLE 24 THE DERMATOLOGY MARKET IN BRAZIL, THROUGH 2018 ($ MILLIONS/%) 86
TABLE 25 THE DERMATOLOGY MARKET IN RUSSIA, THROUGH 2018 ($ MILLIONS/%) 88
TABLE 26 THE DERMATOLOGY MARKET IN INDIA, THROUGH 2018 ($ MILLIONS/%) 88
TABLE 27 HEALTHCARE STATISTICS IN CHINA 2006 VERSUS 2011 ($ BILLIONS/%) 89
TABLE 28 THE DERMATOLOGY MARKET IN CHINA, THROUGH 2018 ($ MILLIONS/%) 90
TABLE 29 IMMUNOTHERAPEUTICS IN SKIN DISEASES 138

LIST OF FIGURES
SUMMARY FIGURE MAJOR GLOBAL DERMATOLOGY MARKETS, 2011-2018 ($
MILLIONS) 8

View This Report »

Find all the market research you need - instantly, in one place.

+1.2 Million Research Documents & Statistics +200,000 Trusted Public Sources 350 Industries With Global Coverage

24/7 Customer Support

Talk to Louis

+1 718 618 4302

Purchase Reports From Reputable Market Research Publishers

PharmaPoint: Non-Small Cell Lung Cancer - Global Drug Forecast and Market Analysis to 2022 - Event-Driven Update

PharmaPoint: Non-Small Cell Lung Cancer - Global Drug Forecast and Market Analysis to 2022 - Event-Driven Update

  • $ 9 995
  • Industry report
  • April 2014
  • by Global Data

PharmaPoint: Non-Small Cell Lung Cancer - Global Drug Forecast and Market Analysis to 2022 - Event-Driven Update Summary Non-Small Cell Lung Cancer (NSCLC) is the most common lung cancer, and the second-most ...

Multiple Sclerosis (MS) Drugs and Biologics : Technologies and Global Markets

Multiple Sclerosis (MS) Drugs and Biologics : Technologies and Global Markets

  • $ 6 650
  • Industry report
  • June 2014
  • by BCC Research

This BCC Research study offers an overview of the multiple sclerosis (MS) disease-modifying product market, including regulatory issues accompanied by detailed analyses and forecasts by product. Its main ...

Sleep Aids : Technologies and Global Markets

Sleep Aids : Technologies and Global Markets

  • $ 6 650
  • Industry report
  • June 2014
  • by BCC Research

Research on the working of the human brain in relation to sleep is a fairly new area, with many new and novel theories. The discovery of new mechanisms and chemicals in the brain has provided expanding ...

Bcc Research Bitopertin Forecast

August 2014 $ 5 500

ReportLinker is an award-winning market research solution that finds, filters and organizes the latest industry data so you get all the market research you need - quickly, in one place.