Global Enzyme-Linked Immunosorbent Assay (ELISA) Industry

  • September 2013
  • -
  • Global Industry Analysts
  • -
  • 215 pages

This report analyzes the worldwide markets for Enzyme-Linked Immunosorbent Assay (ELISA) in US$ Thousand by the following Product Segments: ELISA Kits, and ELISA Development Sets and Antibody Pairs.

The report provides separate comprehensive analytics for the US, Canada, Japan, Europe, Asia-Pacific, Latin America, and Rest of World. Annual estimates and forecasts are provided for the period 2010 through 2018. Also, a six-year historic analysis is provided for these markets.

The report profiles 110 companies including many key and niche players such as American Laboratory Products Company, BD Biosciences, BioMerieux SA, Bio-Rad Laboratories, Inc., EMD Millipore, Corp., Life Technologies Corporation, Ortho-Clinical Diagnostics, Inc., R&D Systems, Inc., Thermo Fisher Scientific, Inc., and ZEUS Scientific, Inc. Market data and analytics are derived from primary and secondary research. Company profiles are primarily based on public domain information including company URLs.

Table Of Contents




I. INTRODUCTION, METHODOLOGY and PRODUCT DEFINITIONS
Study Reliability and Reporting Limitations I-1
Disclaimers I-2
Data Interpretation and Reporting Level I-2
Quantitative Techniques and Analytics I-3
Product Definitions and Scope of Study I-3
ELISA Kits I-3
ELISA Development Sets and Antibody Pairs I-3


II. EXECUTIVE SUMMARY

1. INDUSTRY OVERVIEW II-1
ELISA - A Renowned and Proven Assay Format II-1
Factors Sustaining Market II-1
Factors Restraining Growth II-1
Current and Future Analysis II-2
ELISA amid A Challenging Environment II-2
Strategies to Counter Competition II-2
Technological Advances to buoy ELISA’s Prospects II-3
Automation of ELISA - Enabling its Sustenance II-3
Growing Popularity of Multiplexing Deters ELISA Market II-4
Commoditization: A Key Issue Facing ELISA Product Manufacturers II-4
Competitive Landscape II-5
ELISA Products of Select Manufacturers II-5

2. IMMUNOCHEMISTRY - AN INTRODUCTION II-7
Comparison of Various Immunoassay Technologies II-7

3. PRODUCT OVERVIEW II-9
Enzyme-Linked Immunosorbent Assay (ELISA) - An Introduction II-9
ELISA Technique II-9
Steps in ELISA Technique II-9
Testing for Proteins II-10
History II-10
Types of ELISA II-10
Indirect ELISA II-10
Drawbacks II-11
Sandwich ELISA II-11
Advantages II-12
Competitive ELISA II-12
Reverse ELISA II-12
Advantages II-13
Research ELISA Market II-13
ELISA Development Sets and Antibody Pairs II-13
ELISA Kits II-13
Applications of ELISA II-13
ELISA in HIV II-14

4. PRODUCT INNOVATIONS/INTRODUCTIONS II-15
Randox Unveils ELISA for Detection of Next-Generation
Synthetic Cannabinoids II-15
Romer Unveils New AgraQuant® Cashew Elisa II-15
Neogen Unveils New Spice ELISA Test II-15
Randox Unveils Three Elisa Test Kits II-15
Enzo Introduces New Hydroxycholesterol ELISA Kit II-16
Icosagen Unveils CDNF ELISA KIT II-16
Randox Launches New ELISA Tests for Detection of Bath Salts II-16
Pribo Lab Unveils New Melamine Elisa Kit II-17
Alpco Unveils New Human Osteopontin ELISA II-17
Eagle Launches New Vitamin Assay Kits II-17
Eagle Launches New Catecholamine ELISA Assays Kits II-17
Romer Unveils Two AgraQuant® ELISA Kits II-18
Alpco Unveils STELLUX Chemiluminescent ELISA II-18
AnaSpec Launches SensoLyte® ELISA Kits II-18
Alpco Diagnostics Launches New ELISA Test Kits II-18
Stellar Biotechnologies Introduces Stellar KLHâ„¢ ELISA Test Kits II-19
Alpco Diagnostics Introduces Mouse Sclerostin ELISA II-19
Neurotune Unveils NTCAF ELISA II-19
Eagle Biosciences Launches 25-OH Vitamin D ELISA II-19
Pro-Lab Diagnostics Unveils Prolisa Cryptosporidium/Giardia
EIA Kit II-20
Bioo Scientific Introduces Two MaxSignal® Aflatoxin M1 ELISA Kits II-20
Thermo Fisher Scientific Launches IL17A and ITAC ELISA Kits II-20
AnaSpec Launches a Range of Anti-MOG ELISA Assay Kits II-20
Bioo Scientific Introduces MaxSignal Benzo[a]pyrene ELISA Kit II-21
Eagle Biosciences Unveils Mouse Monoclonal Antibody Isotyping
ELISA Kit II-21
Enzo Life Sciences Introduces SMN ELISA Kit II-21
Kane Biotech Introduces DispersinB ELISA Kit II-22
Bioo Scientific Introduces MaxSignal® Melamine ELISA Kit II-22
Enzo Life Sciences Launches PEGylated Protein ELISA Kit II-22
PBL Releases VeriPlex Human Interferon Multiflex ELISA Kit II-23
Enzo Life Sciences Unveils NBR1 and p62 ELISA Kits II-23
NovaTeinBio Introduces ELISA Kits for Laboratory Testing
Applications II-23
Eagle Unveils an Apolipoprotein E ELISA Assay Kit II-23
Eagle Launches ADMA ELISA, SDMA ELISA and ADMA and Arginine ELISA II-24
Eagle Launches TPS® ELISA, TPAcyk™ ELISA and UBA™ II ELISA II-24
Eagle Introduces Two Catecholamine ELISA Kits II-24

5. RECENT INDUSTRY ACTIVITY II-25
Immuno-Biological Laboratories Inks Agreement with WILEX II-25
Argutus Medical Changes Names to EKF Diagnostics Ltd II-25
Wilex Signs Distribution Agreement with GeneDiagnostics II-25
BioTez Selects Eagle Biosciences as Exclusive Distributor in
North America II-25
Biohit Inks Distribution Agreement with Gold Standard Diagnostics II-26
Bio-Rad Acquires Antibody Manufacturer AbD Serotec II-26
Aushon BioSystems Inks Distribution Agreement with AH Diagnostics II-26
IBT Signs an Exclusive Distribution Agreement with Eagle
Biosciences II-26
Life Technologies Enters into Partnership with Sino Biological II-27
Avioq Gets FDA Approval for HTLV-I/II Microelisa System II-27
Bio-Rad Obtains FDA Premarket Application Approval for GS HIV
Combo Ag/Ab EIA II-27
Thermo Fisher Sets-Up a Molecular Biology Center of Excellence
in Lithuania II-28
ZEUS Receives FDA Clearance for ZEUS ELISATM II-28
Dynex Technologies Secures SFDA for DS2 Automated ELISA Analyzer II-28
Dynex Inks Supply Deal with Techlab™® II-28
One Lambda Complete a Supply Agreement with CellTrend II-29
Dynex Inks Supply Deal with Zeus II-29
Biomedicals Bags ANVISA Approval to Market Diagnostic Products
in Brazil II-29
Ivax Diagnostics Secures US FDA Approval for Mago 4S II-30
ORGENTEC Diagnostika Introduces ELISA Test Systems for Alegria® II-30
Stellar Biotechnologies Inks Agreement with Life Diagnostics II-30
Corgenix Medical Inks Distribution Agreement with AXA Diagnostics II-31

6. FOCUS ON SELECT PLAYERS II-32
American Laboratory Products Company (ALPCO) (US) II-32
BD Biosciences (US) II-32
BioMerieux SA (France) II-32
Bio-Rad Laboratories, Inc. (US) II-33
EMD Millipore, Corp. (US) II-34
Life Technologies Corporation (US) II-34
Ortho-Clinical Diagnostics, Inc. (US) II-35
RandD Systems, Inc. (US) II-35
Thermo Fisher Scientific, Inc. (US) II-36
ZEUS Scientific, Inc. (US) II-36

7. GLOBAL MARKET PERSPECTIVE II-38
Analysis by Region II-38
Table 1: World Recent Past, Current and Future Analysis for
Research ELISA by Geographic Region - US, Canada, Japan,
Europe, Asia-Pacific, Latin America and Rest of World Markets
Independently Analyzed with Annual Sales Figures in US$
Thousand for Years 2010 through 2018 (includes corresponding
Graph/Chart) II-38

Table 2: World Historic Review for Research ELISA by
Geographic Region - US, Canada, Japan, Europe, Asia-Pacific,
Latin America and Rest of World Markets Independently
Analyzed with Annual Sales Figures in US$ Thousand for Years
2004 through 2009 (includes corresponding Graph/Chart) II-39

Table 3: World 15-Year Perspective for Research ELISA by
Geographic Region - Percentage Breakdown of Dollar Sales for
US, Canada, Japan, Europe, Asia-Pacific, Latin America and
Rest of World Markets for Years 2004, 2013 and 2018 (includes
corresponding Graph/Chart) II-40
Analysis by Segment II-41
Table 4: World Recent Past, Current and Future Analysis for
ELISA Development Sets and Antibody Pairs by Geographic
Region - US, Canada, Japan, Europe, Asia-Pacific, Latin
America and Rest of World Markets Independently Analyzed with
Annual Sales Figures in US$ Thousand for Years 2010 through
2018 (includes corresponding Graph/Chart) II-41

Table 5: World Historic Review for ELISA Development Sets and
Antibody Pairs by Geographic Region - US, Canada, Japan,
Europe, Asia-Pacific, Latin America and Rest of World Markets
Independently Analyzed with Annual Sales Figures in US$
Thousand for Years 2004 through 2009 (includes corresponding
Graph/Chart) II-42

Table 6: World 15-Year Perspective for ELISA Development Sets
and Antibody Pairs by Geographic Region - Percentage
Breakdown of Dollar Sales for US, Canada, Japan, Europe,
Asia-Pacific, Latin America and Rest of World Markets for
Years 2004, 2013 and 2018 (includes corresponding Graph/Chart) II-43

Table 7: World Recent Past, Current and Future Analysis for
ELISA Kits by Geographic Region - US, Canada, Japan, Europe,
Asia-Pacific, Latin America and Rest of World Markets
Independently Analyzed with Annual Sales Figures in US$
Thousand for Years 2010 through 2018 (includes corresponding
Graph/Chart) II-44

Table 8: World Historic Review for ELISA Kits by Geographic
Region - US, Canada, Japan, Europe, Asia-Pacific, Latin
America and Rest of World Markets Independently Analyzed with
Annual Sales Figures in US$ Thousand for Years 2004 through
2009 (includes corresponding Graph/Chart) II-45

Table 9: World 15-Year Perspective for ELISA Kits by
Geographic Region - Percentage Breakdown of Dollar Sales for
US, Canada, Japan, Europe, Asia-Pacific, Latin America and
Rest of World Markets for Years 2004, 2013 and 2018 (includes
corresponding Graph/Chart) II-46


III. MARKET

1. THE UNITED STATES III-1
A.Market Analysis III-1
Current and Future Analysis III-1
An Overview of ELISA Usage III-1
Leading Applications of ELISA in the US III-2
Leading Analytes/Samples Analyzed using ELISA in the US III-2
Comparison of ELISA Product Offerings of Select Players:
Depicted by Presence in Product Segments - Reagents, Kits
and Assays; Plate Washers and Coated Microplates III-3
Product Launches III-3
Strategic Corporate Developments III-11
Select Major Players III-15
B.Market Analytics III-20
Table 10: The US Recent Past, Current and Future Analysis for
Research ELISA by Product Segment - ELISA Development Sets
and Antibody Pairs, and ELISA Kits Markets Independently
Analyzed with Annual Sales Figures in US$ Thousand for Years
2010 through 2018 (includes corresponding Graph/Chart) III-20

Table 11: The US Historic Review for Research ELISA by
Product Segment - ELISA Development Sets and Antibody Pairs,
and ELISA Kits Markets Independently Analyzed with Annual
Sales Figures in US$ Thousand for Years 2004 through 2009
(includes corresponding Graph/Chart) III-21

Table 12: The US 15-Year Perspective for Research ELISA by
Product Segment - Percentage Breakdown of Dollar Sales for
ELISA Development Sets and Antibody Pairs, and ELISA Kits
Markets for Years 2004, 2013 and 2018 (includes corresponding
Graph/Chart) III-22

2. CANADA III-23
A.Market Analysis III-23
Current and Future Analysis III-23
Product Launches III-23
B.Market Analytics III-24
Table 13: Canadian Recent Past, Current and Future Analysis
for Research ELISA by Product Segment - ELISA Development
Sets and Antibody Pairs, and ELISA Kits Markets
Independently Analyzed with Annual Sales Figures in US$
Thousand for Years 2010 through 2018 (includes corresponding
Graph/Chart) III-24

Table 14: Canadian Historic Review for Research ELISA by
Product Segment - ELISA Development Sets and Antibody Pairs,
and ELISA Kits Markets Independently Analyzed with Annual
Sales Figures in US$ Thousand for Years 2004 through 2009
(includes corresponding Graph/Chart) III-25

Table 15: Canadian 15-Year Perspective for Research ELISA by
Product Segment - Percentage Breakdown of Dollar Sales for
ELISA Development Sets and Antibody Pairs, and ELISA Kits
Markets for Years 2004, 2013 and 2018 (includes corresponding
Graph/Chart) III-26

3. JAPAN III-27
A.Market Analysis III-27
Current and Future Analysis III-27
B.Market Analytics III-27
Table 16: Japanese Recent Past, Current and Future Analysis
for Research ELISA by Product Segment - ELISA Development
Sets and Antibody Pairs, and ELISA Kits Markets
Independently Analyzed with Annual Sales Figures in US$
Thousand for Years 2010 through 2018 (includes corresponding
Graph/Chart) III-27

Table 17: Japanese Historic Review for Research ELISA by
Product Segment - ELISA Development Sets and Antibody Pairs,
and ELISA Kits Markets Independently Analyzed with Annual
Sales Figures in US$ Thousand for Years 2004 through 2009
(includes corresponding Graph/Chart) III-28

Table 18: Japanese 15-Year Perspective for Research ELISA by
Product Segment - Percentage Breakdown of Dollar Sales for
ELISA Development Sets and Antibody Pairs, and ELISA Kits
Markets for Years 2004, 2013 and 2018 (includes corresponding
Graph/Chart) III-29

4. EUROPE III-30
A.Market Analysis III-30
Current and Future Analysis III-30
B.Market Analytics III-30
Table 19: European Recent Past, Current and Future Analysis
for Research ELISA by Geographic Region - France, Germany,
Italy, UK, and Rest of Europe Markets Independently Analyzed
with Annual Sales Figures in US$ Thousand for Years 2010
through 2018 (includes corresponding Graph/Chart) III-30

Table 20: European Historic Review for Research ELISA by
Geographic Region - France, Germany, Italy, UK, and Rest of
Europe Markets Independently Analyzed with Annual Sales
Figures in US$ Thousand for Years 2004 through 2009
(includes corresponding Graph/Chart) III-31

Table 21: European 15-Year Perspective for Research ELISA by
Geographic Region - Percentage Breakdown of Dollar Sales for
France, Germany, Italy, UK, and Rest of Europe Markets for
Years 2004, 2013 and 2018 (includes corresponding Graph/Chart) III-32

Table 22: European Recent Past, Current and Future Analysis
for Research ELISA by Product Segment - ELISA Development
Sets and Antibody Pairs, and ELISA Kits Markets
Independently Analyzed with Annual Sales Figures in US$
Thousand for Years 2010 through 2018 (includes corresponding
Graph/Chart) III-33

Table 23: European Historic Review for Research ELISA by
Product Segment - ELISA Development Sets and Antibody Pairs,
and ELISA Kits Markets Independently Analyzed with Annual
Sales Figures in US$ Thousand for Years 2004 through 2009
(includes corresponding Graph/Chart) III-34

Table 24: European 15-Year Perspective for Research ELISA by
Product Segment - Percentage Breakdown of Dollar Sales for
ELISA Development Sets and Antibody Pairs, and ELISA Kits
Markets for Years 2004, 2013 and 2018 (includes corresponding
Graph/Chart) III-35

4a. FRANCE III-36
A.Market Analysis III-36
Current and Future Analysis III-36
BioMerieux SA - A Key Player III-36
B.Market Analytics III-37
Table 25: French Recent Past, Current and Future Analysis for
Research ELISA by Product Segment - ELISA Development Sets
and Antibody Pairs, and ELISA Kits Markets Independently
Analyzed with Annual Sales Figures in US$ Thousand for Years
2010 through 2018 (includes corresponding Graph/Chart) III-37

Table 26: French Historic Review for Research ELISA by
Product Segment - ELISA Development Sets and Antibody Pairs,
and ELISA Kits Markets Independently Analyzed with Annual
Sales Figures in US$ Thousand for Years 2004 through 2009
(includes corresponding Graph/Chart) III-38

Table 27: French 15-Year Perspective for Research ELISA by
Product Segment - Percentage Breakdown of Dollar Sales for
ELISA Development Sets and Antibody Pairs, and ELISA Kits
Markets for Years 2004, 2013 and 2018 (includes corresponding
Graph/Chart) III-39

4b. GERMANY III-40
A.Market Analysis III-40
Current and Future Analysis III-40
Strategic Corporate Developments III-40
B.Market Analytics III-41
Table 28: German Recent Past, Current and Future Analysis for
Research ELISA by Product Segment - ELISA Development Sets
and Antibody Pairs, and ELISA Kits Markets Independently
Analyzed with Annual Sales Figures in US$ Thousand for Years
2010 through 2018 (includes corresponding Graph/Chart) III-41

Table 29: German Historic Review for Research ELISA by
Product Segment - ELISA Development Sets and Antibody Pairs,
and ELISA Kits Markets Independently Analyzed with Annual
Sales Figures in US$ Thousand for Years 2004 through 2009
(includes corresponding Graph/Chart) III-42

Table 30: German 15-Year Perspective for Research ELISA by
Product Segment - Percentage Breakdown of Dollar Sales for
ELISA Development Sets and Antibody Pairs, and ELISA Kits
Markets for Years 2004, 2013 and 2018 (includes corresponding
Graph/Chart) III-43

4c. ITALY III-44
A.Market Analysis III-44
Current and Future Analysis III-44
B.Market Analytics III-44
Table 31: Italian Recent Past, Current and Future Analysis for
Research ELISA by Product Segment - ELISA Development Sets
and Antibody Pairs, and ELISA Kits Markets Independently
Analyzed with Annual Sales Figures in US$ Thousand for Years
2010 through 2018 (includes corresponding Graph/Chart) III-44

Table 32: Italian Historic Review for Research ELISA by
Product Segment - ELISA Development Sets and Antibody Pairs,
and ELISA Kits Markets Independently Analyzed with Annual
Sales Figures in US$ Thousand for Years 2004 through 2009
(includes corresponding Graph/Chart) III-45

Table 33: Italian 15-Year Perspective for Research ELISA by
Product Segment - Percentage Breakdown of Dollar Sales for
ELISA Development Sets and Antibody Pairs, and ELISA Kits
Markets for Years 2004, 2013 and 2018 (includes corresponding
Graph/Chart) III-46

4d. THE UNITED KINGDOM III-47
A.Market Analysis III-47
Current and Future Analysis III-47
Product Launches III-47
B.Market Analytics III-48
Table 34: UK Recent Past, Current and Future Analysis for
Research ELISA by Product Segment - ELISA Development Sets
and Antibody Pairs, and ELISA Kits Markets Independently
Analyzed with Annual Sales Figures in US$ Thousand for Years
2010 through 2018 (includes corresponding Graph/Chart) III-48

Table 35: UK Historic Review for Research ELISA by Product
Segment - ELISA Development Sets and Antibody Pairs, and
ELISA Kits Markets Independently Analyzed with Annual Sales
Figures in US$ Thousand for Years 2004 through 2009
(includes corresponding Graph/Chart) III-49

Table 36: UK 15-Year Perspective for Research ELISA by
Product Segment - Percentage Breakdown of Dollar Sales for
ELISA Development Sets and Antibody Pairs, and ELISA Kits
Markets for Years 2004, 2013 and 2018 (includes corresponding
Graph/Chart) III-50

4e. REST OF EUROPE III-51
A.Market Analysis III-51
Current and Future Analysis III-51
Product Launches III-51
Strategic Corporate Developments III-51
B.Market Analytics III-53
Table 37: Rest of Europe Recent Past, Current and Future
Analysis for Research ELISA by Product Segment - ELISA
Development Sets and Antibody Pairs, and ELISA Kits Markets
Independently Analyzed with Annual Sales Figures in US$
Thousand for Years 2010 through 2018 (includes corresponding
Graph/Chart) III-53

Table 38: Rest of Europe Historic Review for Research ELISA
by Product Segment - ELISA Development Sets and Antibody
Pairs, and ELISA Kits Markets Independently Analyzed with
Annual Sales Figures in US$ Thousand for Years 2004 through
2009 (includes corresponding Graph/Chart) III-54

Table 39: Rest of Europe 15-Year Perspective for Research
ELISA by Product Segment - Percentage Breakdown of Dollar
Sales for ELISA Development Sets and Antibody Pairs, and
ELISA Kits Markets for Years 2004, 2013 and 2018 (includes
corresponding Graph/Chart) III-55

5. ASIA-PACIFIC III-56
A.Market Analysis III-56
Current and Future Analysis III-56
Product Launches III-56
Strategic Corporate Developments III-57
B.Market Analytics III-58
Table 40: Asia-Pacific Recent Past, Current and Future
Analysis for Research ELISA by Product Segment - ELISA
Development Sets and Antibody Pairs, and ELISA Kits Markets
Independently Analyzed with Annual Sales Figures in US$
Thousand for Years 2010 through 2018 (includes corresponding
Graph/Chart) III-58

Table 41: Asia-Pacific Historic Review for Research ELISA by
Product Segment - ELISA Development Sets and Antibody Pairs,
and ELISA Kits Markets Independently Analyzed with Annual
Sales Figures in US$ Thousand for Years 2004 through 2009
(includes corresponding Graph/Chart) III-59

Table 42: Asia-Pacific 15-Year Perspective for Research
ELISA by Product Segment - Percentage Breakdown of Dollar
Sales for ELISA Development Sets and Antibody Pairs, and
ELISA Kits Markets for Years 2004, 2013 and 2018 (includes
corresponding Graph/Chart) III-60

6. LATIN AMERICA III-61
A.Market Analysis III-61
Current and Future Analysis III-61
Strategic Corporate Development III-61
B.Market Analytics III-62
Table 43: Latin American Recent Past, Current and Future
Analysis for Research ELISA by Product Segment - ELISA
Development Sets and Antibody Pairs, and ELISA Kits Markets
Independently Analyzed with Annual Sales Figures in US$
Thousand for Years 2010 through 2018 (includes corresponding
Graph/Chart) III-62

Table 44: Latin American Historic Review for Research ELISA
by Product Segment - ELISA Development Sets and Antibody
Pairs, and ELISA Kits Markets Independently Analyzed with
Annual Sales Figures in US$ Thousand for Years 2004 through
2009 (includes corresponding Graph/Chart) III-63

Table 45: Latin American 15-Year Perspective for Research
ELISA by Product Segment - Percentage Breakdown of Dollar
Sales for ELISA Development Sets and Antibody Pairs, and
ELISA Kits Markets for Years 2004, 2013 and 2018 (includes
corresponding Graph/Chart) III-64

7. REST OF WORLD III-65
A.Market Analysis III-65
Current and Future Analysis III-65
B.Market Analytics III-65
Table 46: Rest of World Recent Past, Current and Future
Analysis for Research ELISA by Product Segment - ELISA
Development Sets and Antibody Pairs, and ELISA Kits Markets
Independently Analyzed with Annual Sales Figures in US$
Thousand for Years 2010 through 2018 (includes corresponding
Graph/Chart) III-65

Table 47: Rest of World Historic Review for Research ELISA
by Product Segment - ELISA Development Sets and Antibody
Pairs, and ELISA Kits Markets Independently Analyzed with
Annual Sales Figures in US$ Thousand for Years 2004 through
2009 (includes corresponding Graph/Chart) III-66

Table 48: Rest of World 15-Year Perspective for Research
ELISA by Product Segment - Percentage Breakdown of Dollar
Sales for ELISA Development Sets and Antibody Pairs, and
ELISA Kits Markets for Years 2004, 2013 and 2018 (includes
corresponding Graph/Chart) III-67


IV. COMPETITIVE LANDSCAPE

Total Companies Profiled: 110 (including Divisions/Subsidiaries - 117)
The United States (76)
Canada (3)
Japan (1)
Europe (28)
- France (1)
- Germany (8)
- The United Kingdom (8)
- Spain (1)
- Rest of Europe (10)
Asia-Pacific (Excluding Japan) (9)

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