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Global Intravascular Ultrasound (IVUS) Industry

  • March 2015
  • -
  • Global Industry Analysts
  • -
  • 196 pages

This report analyzes the worldwide markets for Intravascular Ultrasound (IVUS) in US$ Thousands by the following Product Segments: Intravascular Ultrasound (IVUS) Catheters, and Intravascular Ultrasound (IVUS) Consoles. The report provides separate comprehensive analytics for the US, Canada, Japan, Europe, Asia-Pacific, Latin America, and Rest of World. Annual estimates and forecasts are provided for the period 2014 through 2020. Also, a seven-year historic analysis is provided for these markets. Market data and analytics are derived from primary and secondary research. Company profiles are primarily based on public domain information including company URLs. The report profiles 8 companies including many key and niche players such as -

Boston Scientific Corporation
InfraReDx, Inc.
Philips Healthcare
Terumo Corp.

Table Of Contents

Global Intravascular Ultrasound (IVUS) Industry


I. INTRODUCTION, METHODOLOGY and PRODUCT DEFINITIONS

Study Reliability and Reporting Limitations I-1 Disclaimers.............. I-2 Data Interpretation and Reporting Level I-2 Quantitative Techniques and Analytics I-3 Product Definitions and Scope of Study I-3 Intravascular Ultrasound (IVUS) Catheters I-3 Intravascular Ultrasound (IVUS) Consoles I-4

II. EXECUTIVE SUMMARY

1. INDUSTRY OVERVIEW.............. II-1 IVUS - The Fast Growing Segment in Interventional Cardiology II-1 Growth Drivers.............. II-1 Growth Restraints/Key Challenges II-2 US and Japan Take the Lead, Developing Countries Spearhead Growth II-2 IVUS Catheters Remain the Key Revenue Spinners II-3 Select Approved IVUS Catheters in the Market II-4 Select Approved IVUS Consoles in the Market II-4 Coronary Artery - the Leading Target Market for IVUS II-4 Stents Transform CAD Treatment, IVUS Expands Efficacy II-5 IVUS - An Apposite Supplement to Contrast Angiography II-5

2. MARKET TRENDS, DRIVERS AND ISSUES II-7 Lower Penetration Worldwide Bodes Brighter Prospects Ahead II-7 Table 1: Number of PCI Procedures in US, Europe, and Japan in Thousands: 2013 (includes corresponding Graph/Chart) II-7 Superior Capabilities over Angiography Propels IVUS Adoption II-7 Strong Clinical Evidence and Technological Improvements Support IVUS Sales.............. II-8 Providing Regional Observations to Study Predictors of Events in the Coronary Tree (PROSPECT) II-8 Clinical Studies Critical in Encouraging Physicians to Take Up IVUS.............. II-8 Emerging Economies to Power Growth of IVUS Consoles and Catheters II-9 Aging Population: A Strong Growth Driver II-9 Table 2: Global Aging Population (over the age of 60) and their Proportion of Total Population by Select Country: 2014 (includes corresponding Graph/Chart) II-10

Table 3: Elderly Population (60+ Years) as a Percentage of the Total Population (2012 and 2050) (includes corresponding Graph/Chart).............. II-11 Increasing Obesity Levels Underpin Market Growth II-11 Table 4: Obese and Overweight and Obese Population in the World (2013): Percentage Share Breakdown by Region for US, European Union, and Rest of World (includes corresponding Graph/Chart) II-12

Table 5: Global Obesity Population by Region/ Country (2013) (In Million) (includes corresponding Graph/Chart) II-12 Improving Healthcare Expenditure to Drive Demand II-13 Table 6: Per-Capita Healthcare Expenditure in Select Regions (2013) (includes corresponding Graph/Chart) II-14

Table 7: Healthcare Spending as a Percentage of GDP (2012) (includes corresponding Graph/Chart) II-14 Increasing Application of IVUS in Stent Deployment and Assessment II-15 Emergence of Multi-Modality System to Drive Increasing Usage of IVUS.............. II-15 IVUS Imaging Aids Physicians in Filing Documentation for Reimbursement Claims..............II-15 IVUS Addresses Growing Need for Minimally Invasive Procedures II-15 Staff Training Vital for Realizing True Potential of IVUS in Catheterization Labs..............II-16 Major Advances Transfigure Image Assessment in IVUS II-16 An Overview of the IVUS Catheter Transducer Technology II-17 Capacitive Micromachined Ultrasonic Transducers (cMUT) Capture Manufacturers' Attention II-17 Integrated IVUS Consoles Enhance Workflow II-17 FL-IVUS - Expanding Indications of IVUS II-18 IVUS Assumes New Role in Balloon Angioplasty II-18 Software Component Adds Further Assessment Capabilities II-18 Motorized or Manual Transducer Pullback II-19 The Road Ahead.............. II-19

3. ISSUES AND CHALLENGES..............II-21 Reimbursement - A Major Issue Affecting IVUS Adoption Worldwide II-21 Cost and Time - Key Drawbacks of IVUS Technique II-22 Facilities May Face Difficulty in Justifying Mounted Costs II-22 Technical Limitations..............II-22 Stifled Innovation - the Reason for Increasing Competition II-22 Competing Techniques Emerge with Superior Efficacy II-23 IVUS versus OCT.............. II-23 Comparison of IVUS and OCT..............II-24 FFR Gaining Rapid Adoption..............II-24 Non-Use Remains a Major Threat II-24 Other Issues.............. II-25 Are Integrated Systems the Future of IVUS? II-25

4. COMPETITIVE LANDSCAPE..............II-26 Overview.............. II-26 Key Competitors.............. II-26 Volcano's Domination in the Market II-26 Table 8: Leading Players in the Global IVUS Market (2014): Percentage Breakdown of Value Sales for Volcano, Boston Scientific, and Others (includes corresponding Graph/Chart) II-27 Volcano Gains Market Share amid Headwinds II-27 Novel Approaches Help Volcano Scale Up in Competition II-28 Will Philips' Acquisition Help Volcano Regain Momentum? II-28

5. CLINICAL STUDIES.............. II-29 The IVUSCTO Study.............. II-29 The PROSPECT Study..............II-29 The Aftermath of PROSPECT Trial II-30 The VERDICT Trial.............. II-30 Assessment of Dual AntiPlatelet Therapy with Drug-Eluting Stents (ADAPT-DES).............. II-31 Several Studies Line Up for Evaluating IVUS II-31

6. PRODUCT OVERVIEW.............. II-33 Intravascular Ultrasound - A Brief Introduction II-33 An Insight into Coronary Heart Disease II-33 Role of IVUS during Percutaneous Coronary Intervention II-33 IVUS Procedure - An Overview..............II-34 Components of IVUS System..............II-34 Intravascular Ultrasound (IVUS) Catheters II-34 Intravascular Ultrasound (IVUS) Consoles II-35 Stenting - A Prevalent Application Area of IVUS II-35 Clinical Applications of IVUS..............II-36 Ensuring Proper Measurements and Confirming CT Measurement in Placement of Stent Graft..............II-36 Balloon Angioplasty..............II-36 Acts as a Substitute in Absence of MR or CT II-37 IVUS for Assessing Treatment Results II-37 Helpful in Selecting Suitable Atherectomy Device II-37 Measurements through IVUS Enable Adequate Placement of Stent -Graft.............. II-37 IVUS Facilitates in Contrast Reduction and Dissection Procedures II-37 IVUS Filter Placements..............II-38 Vena Cava Filter.............. II-38 Other Applications.............. II-38

7. CORONARY STENTS MARKET - A BRIEF OVERVIEW II-39 Growth Revives as Drug Eluting Stents Bounce Back II-39 Drug Eluting Stents Steal the Show II-39 Drug Eluting Stent System - Safety Concerns II-40 What's Next on Cards in Coronary Stents Market? II-40 Major Market Trends.............. II-41 Restenosis - the Real Growth Driver II-41 Aging Population Propels Coronary Stent Market II-41 Direct Stenting Systems Spur Growth II-41 Drug Choice Impacts Market Entry II-41 Next Generation Stents - A Boon for Treating Coronary Diseases II-42 Threats to Coronary Stents - Alternative Therapies/Devices II-42 Coronary Stents Market Challenged by Drug Therapy II-42 Cell Transplantation - A Major Threat to Coronary Stents II-43

8. PRODUCT APPROVALS/INTRODUCTIONS II-44 Infraredx Gains Approval for TVC Imaging System™ and TVC Insight™ Catheter..............II-44 ACIST Medical Systems Introduces HDi™ High-Definition IVUS II-44 Volcano Introduces SyncVision Precision Guidance Tool II-44 Boston Scientific Introduces POLARIS™ Imaging System II-44 Volcano Commences Limited Market Release of SyncVision™ Technology System..............II-44 Volcano Obtains 510(k) Clearance for PreView® Forward-Looking IVUS System.............. II-44 SVMI Receives Special 510(k) Clearance for HD-IVUS Ultrasound Imaging System.............. II-45 Boston Scientific Receives Marketing Approval for OptiCross™ Coronary Imaging Catheter in the US, EU and Japan II-45 PIE Medical Imaging Introduces CAAS IntraVascular Software II-45 Volcano Obtains Clearance for Visions® PV.035 Digital IVUS Catheter.............. II-45 Volcano Obtains Special 510(k) Clearance for Eagle Eye Platinum ST Catheter..............II-45 Volcano Obtains Special 510(k) Clearance for Volcano s5i™ IVUS Imaging and Pressure System..............II-45

9. RECENT INDUSTRY ACTIVITY..............II-46 Royal Philips Acquires Volcano II-46 Acist Inks Commercialization Agreement with Medtronic for FFR -IVUS Technologies.............. II-46 Infraredx Inks Agreement with Philips for Sale of TVC Imaging System.............. II-46 Acist Medical Systems Enters into Strategic Alliance with Medtronic.............. II-46 Nipro Establishes Manufacturing Subsidiary for Commercial Production of Infraredx's TVC Imaging System II-46 Volcano to Acquire Pioneer Plusâ„¢ Range of Products from Medtronic II-47 Volcano Takes Over Crux..............II-47 Volcano Acquires Sync-Rx..............II-47 Nipro Invests in InfraReDx..............II-47 InfraReDx Enters into Exclusive Distribution Agreement with Nipro II-47 Medtronic and Volcano Ink Strategic Alliance II-47 Royal Philips Electronics Enters into Marketing and Distribution Deal with Boston Scientific II-48

10. FOCUS ON SELECT PLAYERS..............II-49 Boston Scientific Corporation (US) II-49 InfraReDx, Inc. (US)..............II-49 Philips Healthcare (Netherlands) II-50 Volcano Corporation (US)..............II-50 Terumo Corp. (Japan)..............II-51

11. GLOBAL MARKET PERSPECTIVE..............II-52 Table 9: World Recent Past, Current and Future Analysis for Intravascular Ultrasound (IVUS) Devices by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific, Latin America and Rest of World Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart) II-52

Table 10: World Historic Review for Intravascular Ultrasound (IVUS) Devices by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific, Latin America and Rest of World Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart).............. II-53

Table 11: World 14-Year Perspective for Intravascular Ultrasound (IVUS) Devices by Geographic Region - Percentage Breakdown of Revenues for US, Canada, Japan, Europe, Asia-Pacific, Latin America and Rest of World Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart) II-54

Table 12: World Recent Past, Current and Future Analysis for Intravascular Ultrasound (IVUS) Catheters by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific, Latin America and Rest of World Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart) II-55

Table 13: World Historic Review for Intravascular Ultrasound (IVUS) Catheters by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific, Latin America and Rest of World Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart).............. II-56

Table 14: World 14-Year Perspective for Intravascular Ultrasound (IVUS) Catheters by Geographic Region - Percentage Breakdown of Revenues for US, Canada, Japan, Europe, Asia-Pacific, Latin America and Rest of World Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart) II-57

Table 15: World Recent Past, Current and Future Analysis for Intravascular Ultrasound (IVUS) Consoles by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific, Latin America and Rest of World Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart) II-58

Table 16: World Historic Review for Intravascular Ultrasound (IVUS) Consoles by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific, Latin America and Rest of World Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart).............. II-59

Table 17: World 14-Year Perspective for Intravascular Ultrasound (IVUS) Consoles by Geographic Region - Percentage Breakdown of Revenues for US, Canada, Japan, Europe, Asia-Pacific, Latin America and Rest of World Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart) II-60

III. MARKET

1. THE UNITED STATES.............. III-1 A.Market Analysis.............. III-1 Outlook.............. III-1 Declining PCI Volumes - A Cause of Concern III-1 Penetration of IVUS Remains Low in PCI Procedures III-2 Class Ia Recommendation - A Vital Step for Universal Adoption of IVUS.............. III-2 Competition Scenario..............III-2 Boston and Volcano Vie for Market Share III-2 Table 18: US IVUS Procedure Market by Company (2010, 2012 and 2014): Percentage Breakdown of Number of Procedures for Volcano and Boston Scientific (includes corresponding Graph/Chart).............. III-3 s5 Multi-Modality System - A Major Success for Volcano III-3 Product Approvals/Launches..............III-4 Strategic Corporate Developments III-5 Key Players.............. III-7 B.Market Analytics..............III-9 Table 19: US Recent Past, Current and Future Analysis for Intravascular Ultrasound (IVUS) Devices by Product Segment - IVUS Catheters and IVUS Consoles Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart) III-9

Table 20: US Historic Review for Intravascular Ultrasound (IVUS) Devices by Product Segment - IVUS Catheters and IVUS Consoles Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-10

Table 21: US 14-Year Perspective for Intravascular Ultrasound (IVUS) Devices by Product Segment - Percentage Breakdown of Revenues for IVUS Catheters and IVUS Consoles Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart)..............III-11

2. CANADA.............. III-12 Market Analysis.............. III-12 Table 22: Canadian Recent Past, Current and Future Analysis for Intravascular Ultrasound (IVUS) Devices by Product Segment - IVUS Catheters and IVUS Consoles Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart).............. III-12

Table 23: Canadian Historic Review for Intravascular Ultrasound (IVUS) Devices by Product Segment - IVUS Catheters and IVUS Consoles Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-13

Table 24: Canadian 14-Year Perspective for Intravascular Ultrasound (IVUS) Devices by Product Segment - Percentage Breakdown of Revenues for IVUS Catheters and IVUS Consoles Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart)..............III-14

3. JAPAN.............. III-15 A.Market Analysis.............. III-15 Japan - A Mature Market for IVUS III-15 Market Trends.............. III-15 High Penetration Typifies Japanese IVUS Market III-15 Flexible Reimbursement Structure Encourages IVUS Adoption III-15 Reimbursement Cuts Affect Revenues III-16 Competitive Scenario..............III-16 Table 25: Japanese IVUS Procedure Market by Company (2014): Percentage Breakdown of Number of Procedures for Volcano, Boston Scientific and Terumo (includes corresponding Graph/Chart).............. III-16 Volcano Forays into Direct Sales in Japan, Eyes Improved Market Share.............. III-16 Product Approval..............III-17 Strategic Corporate Developments III-17 Terumo Corp. - A Major Player In The Japanese Ivus Market III-17 B.Market Analytics..............III-18 Table 26: Japanese Recent Past, Current and Future Analysis for Intravascular Ultrasound (IVUS) Devices by Product Segment - IVUS Catheters and IVUS Consoles Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart).............. III-18

Table 27: Japanese Historic Review for Intravascular Ultrasound (IVUS) Devices by Product Segment - IVUS Catheters and IVUS Consoles Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-19

Table 28: Japanese 14-Year Perspective for Intravascular Ultrasound (IVUS) Devices by Product Segment - Percentage Breakdown of Revenues for IVUS Catheters and IVUS Consoles Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart)..............III-20

4. EUROPE.............. III-21 A.Market Analysis.............. III-21 Current and Future Analysis..............III-21 Lower Penetration Rate Mars European IVUS Market III-21 Table 29: Top 15 European Countries Ranked by Number of Percutaneous Coronary Intervention (PCI) Procedures Performed per Million Inhabitants: 2012 (includes corresponding Graph/Chart)..............III-22

Table 30: Top 15 European Countries Ranked by Percentage of DES in Percutaneous Coronary Intervention (PCI) Procedures: 2012 (includes corresponding Graph/Chart) III-22 High Cost and Lack of Robust Data Restrict Widespread Adoption of IVUS.............. III-23 IVUS to Face Tough Competition from Fractional Flow Reserve III-23 Intravascular Diagnostics to Grow Despite Revenue Dip in Interventional Cardiology Market III-23 B.Market Analytics..............III-24 Table 31: European Recent Past, Current and Future Analysis for Intravascular Ultrasound (IVUS) Devices by Geographic Region - France, Germany, Italy, UK, Spain, Russia, and Rest of Europe Markets Independently Analyzed with Annual Revenue Figures In US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart) III-24

Table 32: European Historic Review for Intravascular Ultrasound (IVUS) Devices by Geographic Region - France, Germany, Italy, UK, Spain, Russia, and Rest of Europe Markets Independently Analyzed with Annual Revenue Figures In US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart)..............III-25

Table 33: European 14-Year Perspective for Intravascular Ultrasound (IVUS) Devices by Geographic Region - Percentage Breakdown of Revenues for France, Germany, Italy, UK, Spain, Russia, and Rest of Europe Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart) III-26

Table 34: European Recent Past, Current and Future Analysis for Intravascular Ultrasound (IVUS) Devices by Product Segment - IVUS Catheters and IVUS Consoles Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart).............. III-27

Table 35: European Historic Review for Intravascular Ultrasound (IVUS) Devices by Product Segment - IVUS Catheters and IVUS Consoles Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-28

Table 36: European 14-Year Perspective for Intravascular Ultrasound (IVUS) Devices by Product Segment - Percentage Breakdown of Revenues for IVUS Catheters and IVUS Consoles Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart)..............III-29

4a. FRANCE.............. III-30 Market Analysis.............. III-30 Table 37: French Recent Past, Current and Future Analysis for Intravascular Ultrasound (IVUS) Devices by Product Segment - IVUS Catheters and IVUS Consoles Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart) III-30

Table 38: French Historic Review for Intravascular Ultrasound (IVUS) Devices by Product Segment - IVUS Catheters and IVUS Consoles Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-31

Table 39: French 14-Year Perspective for Intravascular Ultrasound (IVUS) Devices by Product Segment - Percentage Breakdown of Revenues for IVUS Catheters and IVUS Consoles Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart)..............III-32

4b. GERMANY.............. III-33 Market Analysis.............. III-33 Table 40: German Recent Past, Current and Future Analysis for Intravascular Ultrasound (IVUS) Devices by Product Segment - IVUS Catheters and IVUS Consoles Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart) III-33

Table 41: German Historic Review for Intravascular Ultrasound (IVUS) Devices by Product Segment - IVUS Catheters and IVUS Consoles Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-34

Table 42: German 14-Year Perspective for Intravascular Ultrasound (IVUS) Devices by Product Segment - Percentage Breakdown of Revenues for IVUS Catheters and IVUS Consoles Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart)..............III-35

4c. ITALY.............. III-36 Market Analysis.............. III-36 Table 43: Italian Recent Past, Current and Future Analysis for Intravascular Ultrasound (IVUS) Devices by Product Segment - IVUS Catheters and IVUS Consoles Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart) III-36

Table 44: Italian Historic Review for Intravascular Ultrasound (IVUS) Devices by Product Segment - IVUS Catheters and IVUS Consoles Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-37

Table 45: Italian 14-Year Perspective for Intravascular Ultrasound (IVUS) Devices by Product Segment - Percentage Breakdown of Revenues for IVUS Catheters and IVUS Consoles Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart)..............III-38

4d. THE UNITED KINGDOM..............III-39 A.Market Analysis.............. III-39 Current and Future Analysis..............III-39 PCI Procedural Volume Rises, Growth Slows Down III-39 Table 46: Number of PCI Procedures in the UK: 2004-2013 (includes corresponding Graph/Chart) III-39

Table 47: PCI Procedures in the UK by Country: Number of PCI Procedures per Million Population for Years 2011 and 2013 (includes corresponding Graph/Chart) III-40

Table 48: PCI Procedure Mix in the UK: Percentage Breakdown of Number of Procedures for STEMI, Unstable Angina/ NSTEMI, Stable Angina and Others for Years 2007, 2010 and 2013 (includes corresponding Graph/Chart) III-40 Lower Complications Foster PCI and Stent Growth III-41 Drug Eluting Stent Use Picks Up following Momentary Drop III-41 Table 49: Share of Drug Eluting Stents in the UK Stent Procedure Market: 2004-2013 (includes corresponding Graph/Chart).............. III-41

Table 50: Penetration of Drug Eluting Stent in the UK's PCI Procedure by Country (2011 and 2013) (includes corresponding Graph/Chart)..............III-42 B.Market Analytics..............III-43 Table 51: The UK Recent Past, Current and Future Analysis for Intravascular Ultrasound (IVUS) Devices by Product Segment - IVUS Catheters and IVUS Consoles Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart) III-43

Table 52: The UK Historic Review for Intravascular Ultrasound (IVUS) Devices by Product Segment - IVUS Catheters and IVUS Consoles Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-44

Table 53: The UK 14-Year Perspective for Intravascular Ultrasound (IVUS) Devices by Product Segment - Percentage Breakdown of Revenues for IVUS Catheters and IVUS Consoles Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart)..............III-45

4e. SPAIN.............. III-46 A.Market Analysis.............. III-46 Current and Future Analysis..............III-46 PCI and IVUS Procedures in Spain III-46 Table 54: Number of Percutaneous Coronary Intervention (PCI) Procedures Performed in Spain (in Thousands): 2004-2013 (includes corresponding Graph/Chart) III-46 B.Market Analytics..............III-47 Table 55: Spanish Recent Past, Current and Future Analysis for Intravascular Ultrasound (IVUS) Devices by Product Segment - IVUS Catheters and IVUS Consoles Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart) III-47

Table 56: Spanish Historic Review for Intravascular Ultrasound (IVUS) Devices by Product Segment - IVUS Catheters and IVUS Consoles Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-48

Table 57: Spanish 14-Year Perspective for Intravascular Ultrasound (IVUS) Devices by Product Segment - Percentage Breakdown of Revenues for IVUS Catheters and IVUS Consoles Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart)..............III-49

4f. RUSSIA.............. III-50 Market Analysis.............. III-50 Table 58: Russian Recent Past, Current and Future Analysis for Intravascular Ultrasound (IVUS) Devices by Product Segment - IVUS Catheters and IVUS Consoles Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart) III-50

Table 59: Russian Historic Review for Intravascular Ultrasound (IVUS) Devices by Product Segment - IVUS Catheters and IVUS Consoles Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-51

Table 60: Russian 14-Year Perspective for Intravascular Ultrasound (IVUS) Devices by Product Segment - Percentage Breakdown of Revenues for IVUS Catheters and IVUS Consoles Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart)..............III-52

4g. REST OF EUROPE.............. III-53 A.Market Analysis.............. III-53 Current and Future Analysis..............III-53 Product Launch.............. III-53 Key Player.............. III-53 B.Market Analytics..............III-54 Table 61: Rest of European Recent Past, Current and Future Analysis for Intravascular Ultrasound (IVUS) Devices by Product Segment - IVUS Catheters and IVUS Consoles Markets Independently Analyzed with Annual Revenue Figures In US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart).............. III-54

Table 62: Rest of European Historic Review for Intravascular Ultrasound (IVUS) Devices by Product Segment - IVUS Catheters and IVUS Consoles Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-55

Table 63: Rest of European 14-Year Perspective for Intravascular Ultrasound (IVUS) Devices by Product Segment - Percentage Breakdown of Revenues for IVUS Catheters and IVUS Consoles Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart)..............III-56

5. ASIA-PACIFIC.............. III-57 Market Analysis.............. III-57 Table 64: Asia-Pacific Recent Past, Current and Future Analysis for Intravascular Ultrasound (IVUS) Devices by Geographic Region - China, India, and Rest of Asia-Pacific Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart)..............III-58

Table 65: Asia-Pacific Historic Review for Intravascular Ultrasound (IVUS) Devices by Geographic Region - China, India, and Rest of Asia-Pacific Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-59

Table 66: Asia-Pacific 14-Year Perspective for Intravascular Ultrasound (IVUS) Devices by Geographic Region - Percentage Breakdown of Revenues for China, India, and Rest of Asia-Pacific Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart)..............III-60

Table 67: Asia-Pacific Recent Past, Current and Future Analysis for Intravascular Ultrasound (IVUS) Devices by Product Segment - IVUS Catheters and IVUS Consoles Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart).............. III-61

Table 68: Asia-Pacific Historic Review for Intravascular Ultrasound (IVUS) Devices by Product Segment - IVUS Catheters and IVUS Consoles Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-62

Table 69: Asia-Pacific 14-Year Perspective for Intravascular Ultrasound (IVUS) Devices by Product Segment - Percentage Breakdown of Revenues for IVUS Catheters and IVUS Consoles Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart)..............III-63

5a. CHINA.............. III-64 A.Market Analysis.............. III-64 Current and Future Analysis..............III-64 Rising PCI Procedure Volume in China III-64 Table 70: PCI Procedural Volume in China (2006-2013) (includes corresponding Graph/Chart) III-64 B.Market Analytics..............III-65 Table 71: Chinese Recent Past, Current and Future Analysis for Intravascular Ultrasound (IVUS) Devices by Product Segment - IVUS Catheters and IVUS Consoles Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart) III-65

Table 72: Chinese Historic Review for Intravascular Ultrasound (IVUS) Devices by Product Segment - IVUS Catheters and IVUS Consoles Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-66

Table 73: Chinese 14-Year Perspective for Intravascular Ultrasound (IVUS) Devices by Product Segment - Percentage Breakdown of Revenues for IVUS Catheters and IVUS Consoles Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart)..............III-67

5b. INDIA.............. III-68 A.Market Analysis.............. III-68 Current and Future Analysis..............III-68 Absence of Reimbursement Affects IVUS Adoption in Indian Healthcare.............. III-68 B.Market Analytics..............III-69 Table 74: Indian Recent Past, Current and Future Analysis for Intravascular Ultrasound (IVUS) Devices by Product Segment - IVUS Catheters and IVUS Consoles Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart) III-69

Table 75: Indian Historic Review for Intravascular Ultrasound (IVUS) Devices by Product Segment - IVUS Catheters and IVUS Consoles Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-70

Table 76: Indian 14-Year Perspective for Intravascular Ultrasound (IVUS) Devices by Product Segment - Percentage Breakdown of Revenues for IVUS Catheters and IVUS Consoles Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart)..............III-71

5c. REST OF ASIA-PACIFIC..............III-72 Market Analysis.............. III-72 Table 77: Rest of Asia-Pacific Recent Past, Current and Future Analysis for Intravascular Ultrasound (IVUS) Devices by Product Segment - IVUS Catheters and IVUS Consoles Markets Independently Analyzed with Annual Revenue Figures In US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart).............. III-72

Table 78: Rest of Asia-Pacific Historic Review for Intravascular Ultrasound (IVUS) Devices by Product Segment - IVUS Catheters and IVUS Consoles Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-73

Table 79: Rest of Asia-Pacific 14-Year Perspective for Intravascular Ultrasound (IVUS) Devices by Product Segment - Percentage Breakdown of Revenues for IVUS Catheters and IVUS Consoles Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart)..............III-74

6. LATIN AMERICA.............. III-75 Market Analysis.............. III-75 Table 80: Latin American Recent Past, Current and Future Analysis for Intravascular Ultrasound (IVUS) Devices by Geographic Region - Brazil and Rest of Latin American Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart)..............III-75

Table 81: Latin American Historic Review for Intravascular Ultrasound (IVUS) Devices by Geographic Region - Brazil and Rest of Latin American Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-76

Table 82: Latin American 14-Year Perspective for Intravascular Ultrasound (IVUS) Devices by Geographic Region - Percentage Breakdown of Revenues for Brazil and Rest of Latin American Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart) III-77

Table 83: Latin American Recent Past, Current and Future Analysis for Intravascular Ultrasound (IVUS) Devices by Product Segment - IVUS Catheters and IVUS Consoles Markets Independently Analyzed with Annual Revenue Figures In US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart).............. III-78

Table 84: Latin American Historic Review for Intravascular Ultrasound (IVUS) Devices by Product Segment - IVUS Catheters and IVUS Consoles Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-79

Table 85: Latin American 14-Year Perspective for Intravascular Ultrasound (IVUS) Devices by Product Segment - Percentage Breakdown of Revenues for IVUS Catheters and IVUS Consoles Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart)..............III-80

6a. BRAZIL.............. III-81 A.Market Analysis.............. III-81 Current and Future Analysis..............III-81 Brazilian PCI Procedure Volume Remains Low III-81 Reimbursement for Drug Eluting Stents Lacks in Brazil III-81 B.Market Analytics..............III-82 Table 86: Brazilian Recent Past, Current and Future Analysis for Intravascular Ultrasound (IVUS) Devices by Product Segment - IVUS Catheters and IVUS Consoles Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart).............. III-82

Table 87: Brazilian Historic Review for Intravascular Ultrasound (IVUS) Devices by Product Segment - IVUS Catheters and IVUS Consoles Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-83

Table 88: Brazilian 14-Year Perspective for Intravascular Ultrasound (IVUS) Devices by Product Segment - Percentage Breakdown of Revenues for IVUS Catheters and IVUS Consoles Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart)..............III-84

6b. REST OF LATIN AMERICA..............III-85 Market Analysis.............. III-85 Table 89: Rest of Latin American Recent Past, Current and Future Analysis for Intravascular Ultrasound (IVUS) Devices by Product Segment - IVUS Catheters and IVUS Consoles Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart)..............III-85

Table 90: Rest of Latin American Historic Review for Intravascular Ultrasound (IVUS) Devices by Product Segment - IVUS Catheters and IVUS Consoles Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-86

Table 91: Rest of Latin American 14-Year Perspective for Intravascular Ultrasound (IVUS) Devices by Product Segment - Percentage Breakdown of Revenues for IVUS Catheters and IVUS Consoles Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart)..............III-87

7. REST OF WORLD.............. III-88 A.Market Analysis.............. III-88 Current and Future Analysis..............III-88 Strategic Corporate Development III-88 B.Market Analytics..............III-89 Table 92: Rest of World Recent Past, Current and Future Analysis for Intravascular Ultrasound (IVUS) Devices by Product Segment - IVUS Catheters and IVUS Consoles Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart).............. III-89

Table 93: Rest of World Historic Review for Intravascular Ultrasound (IVUS) Devices by Product Segment - IVUS Catheters and IVUS Consoles Markets Independently Analyzed with Annual Revenue Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-90

Table 94: Rest of World 14-Year Perspective for Intravascular Ultrasound (IVUS) Devices by Product Segment - Percentage Breakdown of Revenues for IVUS Catheters and IVUS Consoles Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart)..............III-91

IV. COMPETITIVE LANDSCAPE

Total Companies Profiled: 8 (including Divisions/Subsidiaries - 9)

The United States (5) Japan (2) Europe (2) - Germany (1) - Rest of Europe (1)

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