Chapter- 1: INTRODUCTION -- Complimentary
REASON FOR THE STUDY1
GOALS AND OBJECTIVES1
AUDIENCE1
SCOPE OF REPORT2
METHODS AND SOURCES2
ANALYST CREDENTIALS2
RELATED BCC REPORTS3
BCC ONLINE SERVICES3
DISCLAIMER3
Chapter-2: SUMMARY
SUMMARY TABLE GLOBAL EXCIPIENT MARKET BY MATERIAL TYPE, THROUGH 2014 ($ MILLIONS)4
SUMMARY FIGURE GLOBAL EXCIPIENT MARKET, 2009 AND 2014 ($ MILLIONS)5
SUMMARY (CONTINUED)6
SUMMARY (CONTINUED)7
SUMMARY (CONTINUED)8
SUMMARY (CONTINUED)9
Chapter-3: OVERVIEW
MR. BLECHER’S LETTER10
WHAT IS AN EXCIPIENT?11
WHAT IS AN EXCIPIENT? (CONTINUED)12
THE PHARMACEUTICALS INDUSTRY IN TURMOIL: 2000 TO TODAY12
THE PHARMACEUTICALS INDUSTRY …(CONTINUED)13
THE KNOWLEDGE CRISIS14
THE KNOWLEDGE CRISIS (CONTINUED)15
THE KNOWLEDGE CRISIS (CONTINUED)16
THE NEED FOR NEW EXCIPIENTS17
THE NEED FOR NEW EXCIPIENTS (CONTINUED)18
A NOTE ABOUT DIRECT COMPRESSION19
COPROCESSING IS SPLENDID, BUT IT IS NOT ENOUGH20
QBD AND THE GLOBAL SUPPLY CHAIN CRISIS: TWO TIDAL WAVES21
HOW AND WHY THE QUALITY APPROACH CAME TO PHARMA22
HOW AND WHY THE QUALITY …(CONTINUED)23
HOW AND WHY THE QUALITY …(CONTINUED)24
HOW AND WHY THE QUALITY …(CONTINUED)25
THE BASICS OF QBD IN 1,000 WORDS26
THE BASICS OF QBD IN 1,000 WORDS (CONTINUED)27
THE BASICS OF QBD IN 1,000 WORDS (CONTINUED)28
THE GLOBAL SUPPLY CHAIN CRISIS29
THE GLOBAL SUPPLY CHAIN CRISIS (CONTINUED)30
THE GLOBAL SUPPLY CHAIN CRISIS (CONTINUED)31
CHRONOLOGY, PART II32
CHRONOLOGY, PART II (CONTINUED)33
CHRONOLOGY, PART II (CONTINUED)34
CHRONOLOGY, PART II (CONTINUED)35
CHRONOLOGY, PART II (CONTINUED)36
IS THE WORKFORCE UP TO IT?37
A NOTE ON THE RECESSION38
THE REGULATORY SCENE38
THE REGULATORY SCENE (CONTINUED)39
THE REGULATORY SCENE (CONTINUED)40
Chapter-4: GLOBAL EXCIPIENT MARKET: SEVERAL BASIC FIGURES
FIGURE 1 GLOBAL EXCIPIENT MARKET SHARE BY CATEGORY OF MATERIAL, 2009 (%)41
FIGURE 2 GLOBAL EXCIPIENT MARKET SHARE BY TYPE OF ORGANIC CHEMICAL, 2009 (%)42
FIGURE 3 GLOBAL EXCIPIENT MARKET SHARE BY TYPE OF INORGANIC CHEMICAL, 2009 (%)43
FIGURE 4 GLOBAL EXCIPIENT MARKET SHARE BY TYPE OF USP WATER, 2009 (%)44
FIGURE 5 GLOBAL EXCIPIENT MARKET SHARE BY FUNCTIONAL USE, 2009 (%)45
FIGURE 6 GLOBAL EXCIPIENT MARKET SHARE BY TYPE OF DELIVERY SYSTEM, 2009 (%)46
FIGURE 7 GLOBAL EXCIPIENT MARKET FOR FINISHED PRODUCTS BY TYPE (RX AND OTC), 2009 (%)47
Chapter-5: CHEMICAL COMPOUNDS
CHEMICAL COMPOUNDS48
MARKET SIZE49
TABLE 1 GLOBAL EXCIPIENT MARKET VALUE BY MATERIAL TYPE, THROUGH 2014 ($ MILLIONS)49
TABLE 2 GLOBAL EXCIPIENT MARKET VOLUME BY MATERIAL TYPE, THROUGH 2014 (LBS MILLIONS)50
ORGANIC CHEMICALS50
MARKET SIZE FOR ORGANIC CHEMICALS50
TABLE 3 GLOBAL ORGANIC CHEMICAL EXCIPIENT MARKET VALUE BY TYPE, THROUGH 2014 ($ MILLIONS)51
TABLE 4 GLOBAL ORGANIC CHEMICAL EXCIPIENT MARKET VOLUME BY TYPE, THROUGH 2014 (LBS MILLIONS)51
CARBOHYDRATES51
Market Size51
TABLE 5 GLOBAL CARBOHYDRATE EXCIPIENT MARKET BY TYPE, THROUGH 2014 ($ MILLIONS)52
TABLE 6 GLOBAL CARBOHYDRATE EXCIPIENT MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS)52
Celluloses52
Market Size53
TABLE 7 GLOBAL CELLULOSE EXCIPIENT MARKET BY TYPE, THROUGH 2014 ($ MILLIONS)53
TABLE 8 GLOBAL CELLULOSE EXCIPIENT MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS)53
Microcrystalline Cellulose53
Market Size54
TABLE 9 GLOBAL MCC EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)54
Cellulose Ethers54
Market Size55
TABLE 10 GLOBAL CELLULOSE ETHER EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)55
Cellulose Esters55
Market Size55
TABLE 11 GLOBAL CELLULOSE ESTER EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)56
Carboxymethyl Cellulose and Croscarmellose Sodium56
Market Size57
TABLE 12 GLOBAL CMC AND CROSCARMELLOSE EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)57
Sugars57
Market Size57
TABLE 13 GLOBAL SUGAR EXCIPIENT MARKET BY TYPE, THROUGH 2014 ($ MILLIONS)58
TABLE 14 GLOBAL SUGAR EXCIPIENT MARKET BY TYPE, THROUGH 2014 (MILLION LBS)58
Actual Sugars58
Market Size58
TABLE 15 GLOBAL ACTUAL SUGAR EXCIPIENT MARKET BY TYPE, THROUGH 2014 ($ MILLIONS)59
TABLE 16 GLOBAL ACTUAL SUGAR EXCIPIENT MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS)59
Lactose59
Market Size60
TABLE 17 GLOBAL LACTOSE EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)60
Sucrose60
Market Size60
TABLE 18 GLOBAL SUCROSE EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)61
Dextrose (Glucose)61
Market Size61
TABLE 19 GLOBAL DEXTROSE (GLUCOSE) EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)61
Sugar Alcohols61
Market Size62
TABLE 20 GLOBAL SUGAR ALCOHOL (POLYOL) EXCIPIENT MARKET BY TYPE, THROUGH 2014 ($ MILLIONS)62
TABLE 21 GLOBAL SUGAR ALCOHOL (POLYOL) EXCIPIENT MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS)62
Sorbitol62
Market Size63
TABLE 22 GLOBAL SORBITOL EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)63
Mannitol63
Market Size63
TABLE 23 GLOBAL MANNITOL EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)64
Other Sugar Alcohols64
Market Size64
TABLE 24 GLOBAL OTHER SUGAR ALCOHOL EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)64
Maltitol65
Xylitol65
Erythritol65
Isomalt65
Tagatose66
Trehalose66
Artificial Sweeteners66
Market Size66
TABLE 25 GLOBAL ARTIFICIAL SWEETENER EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)67
Aspartame67
Neotame67
Acesulfame-K68
Saccharin68
Sucralose68
Starches69
Market Size69
TABLE 26 GLOBAL STARCHES EXCIPIENT MARKET BY TYPE, THROUGH 2014 ($ MILLIONS)69
TABLE 27 GLOBAL STARCHES EXCIPIENT MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS)70
Dried Starch70
Market Size70
TABLE 28 GLOBAL DRIED STARCH EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)70
Modified Starch71
Market Size71
TABLE 29 GLOBAL MODIFIED STARCH EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)71
Converted Starch71
Market Size72
TABLE 30 GLOBAL CONVERTED STARCH EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)72
PETROCHEMICALS72
Market Size72
TABLE 31 GLOBAL PETROCHEMICAL EXCIPIENT MARKET BY TYPE, THROUGH 2014 ($ MILLIONS)73
TABLE 32 GLOBAL PETROCHEMICAL EXCIPIENT MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS)73
Glycols73
Market Size74
TABLE 33 GLOBAL GLYCOL EXCIPIENT MARKET BY TYPE, THROUGH 2014 ($ MILLIONS)74
TABLE 34 GLOBAL GLYCOL EXCIPIENT MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS)74
Polyethylene Glycol74
Market Size75
TABLE 35 GLOBAL PEG EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)75
Propylene Glycol75
Market Size75
TABLE 36 GLOBAL PG EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)76
Povidones76
Market Size76
TABLE 37 GLOBAL PVP EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)77
Mineral Hydrocarbons77
Market Size77
TABLE 38 GLOBAL MINERAL HYDROCARBON EXCIPIENT MARKET BY TYPE, THROUGH 2014 ($ MILLIONS)77
TABLE 39 GLOBAL MINERAL HYDROCARBON EXCIPIENT MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS)78
Petrolatum78
Market Size78
TABLE 40 GLOBAL PETROLATUM EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)79
Mineral Waxes79
Market Size79
TABLE 41 GLOBAL MINERAL WAX EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)79
Mineral Oils80
Market Size80
TABLE 42 GLOBAL MINERAL OIL EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)80
Acrylic Polymers80
Market Size81
TABLE 43 GLOBAL ACRYLIC EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)81
Other Petrochemical Materials81
Market Size81
TABLE 44 GLOBAL OTHER PETROCHEMICAL EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)82
Antimicrobials82
Antioxidants82
Dyes and Lakes82
TABLE 45 SYNTHETIC COLORANTS IN PHARMACEUTICALS83
EDTA84
Flavors84
Glycine and Glycylglycine84
Vinyl Polymers84
Silicones85
Miscellaneous Synthetic Petrochemicals85
OLEOCHEMICALS85
Market Size86
TABLE 46 GLOBAL OLEOCHEMICAL EXCIPIENT MARKET BY TYPE, THROUGH 2014 ($ MILLIONS)86
TABLE 47 GLOBAL OLEOCHEMICAL EXCIPIENT MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS)86
Fatty Alcohols87
Market Size87
TABLE 48 GLOBAL FATTY ALCOHOL EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)87
Glycerin87
Market Size88
TABLE 49 GLOBAL GLYCERIN EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)88
Metal Stearates88
Market Size88
TABLE 50 GLOBAL METAL STEARATE EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)89
Other Oleochemicals89
Market Size89
TABLE 51 GLOBAL OTHER OLEOCHEMICAL EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)89
Natural Waxes89
Beeswax90
Candelilla Wax90
Carnauba Wax90
Cocoa and Shea Butters90
Lanolin90
Phospholipids91
Sodium Lauryl Sulfate91
Sorbitan91
Synthetic Glyceryl Esters91
Vegetable Oils91
PROTEINS92
Gelatin92
Market Size92
TABLE 52 GLOBAL PROTEINS (GELATIN) EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)93
Albumin93
OTHER ORGANIC CHEMICALS93
TABLE 53 GLOBAL OTHER ORGANIC CHEMICAL EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)94
Alcohols94
Citric Acid94
Lactic Acid95
Polysaccharide Gums95
Shellac95
INORGANIC CHEMICALS95
MARKET SIZE95
TABLE 54 GLOBAL INORGANIC CHEMICAL EXCIPIENT MARKET BY TYPE, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)96
TABLE 55 GLOBAL INORGANIC CHEMICAL EXCIPIENT MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS)96
CALCIUM SALTS96
Market Size96
TABLE 56 GLOBAL CALCIUM SALT EXCIPIENT MARKET BY TYPE, THROUGH 2014 ($ MILLIONS)97
TABLE 57 GLOBAL CALCIUM SALT EXCIPIENT MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS)97
Calcium Phosphate97
Market Size98
TABLE 58 GLOBAL CALCIUM PHOSPHATE EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)98
Calcium Carbonate98
Market Size99
TABLE 59 GLOBAL CALCIUM CARBONATE EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)99
Calcium Sulfate99
Market Size99
TABLE 60 GLOBAL CALCIUM SULFATE EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)100
HALITES100
Market Size100
TABLE 61 GLOBAL HALITE EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)100
METAL OXIDES101
Market Size101
TABLE 62 GLOBAL METAL OXIDE EXCIPIENT MARKET BY TYPE, THROUGH 2014 ($ MILLIONS)101
TABLE 63 GLOBAL METAL OXIDE EXCIPIENT MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS)101
Titanium Dioxide101
Market Size102
TABLE 64 GLOBAL TIO2 EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)102
Iron Oxide102
Market Size102
TABLE 65 GLOBAL IRON OXIDE EXCIPIENT MARKET THROUGH 2014 ($ MILLIONS/LBS MILLIONS)103
SILICATES103
Market Size103
TABLE 66 GLOBAL SILICATES EXCIPIENT MARKET BY TYPE, THROUGH 2014 ($ MILLIONS)103
TABLE 67 GLOBAL SILICATES EXCIPIENT MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS)104
Silicon Dioxide104
Market Size104
TABLE 68 GLOBAL SILICON DIOXIDE EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)105
Talc105
Market Size105
TABLE 69 GLOBAL TALC EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)106
Clay106
Market Size106
TABLE 70 GLOBAL CLAY EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)106
OTHER INORGANIC CHEMICALS107
Market Size107
TABLE 71 GLOBAL OTHER INORGANIC CHEMICAL EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)107
USP WATER (PHARMACEUTICAL WATER)107
MARKET SIZE108
TABLE 72 GLOBAL USP WATER EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS)108
TABLE 73 GLOBAL USP WATER EXCIPIENT MARKET, THROUGH 2014 (LBS MILLIONS)108
WATER FOR INJECTIONS108
Market Size109
TABLE 74 GLOBAL USP WFI EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLLIONS)109
PURIFIED WATER109
Market Size109
TABLE 75 GLOBAL USP PURIFIED WATER EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLLIONS)110
FUNCTIONAL USES110
TABLE 76 GLOBAL EXCIPIENT FUNCTIONAL USES MARKET BY TYPE, THROUGH 2014 ($ MILLIONS)111
TABLE 77 GLOBAL EXCIPIENT FUNCTIONAL USES MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS)111
FILLERS112
MARKET SIZE112
TABLE 78 GLOBAL EXCIPIENT FILLER MARKET BY TYPE, THROUGH 2014 ($ MILLIONS)112
TABLE 79 GLOBAL EXCIPIENT FILLER MARKET VOLUME BY TYPE, THROUGH 2014 (LBS MILLIONS)113
EMOLLIENTS113
MARKET SIZE113
TABLE 80 GLOBAL EMOLLIENTS EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)114
VEHICLES114
MARKET SIZE114
TABLE 81 GLOBAL VEHICLE EXCIPIENT MARKET BY TYPE, THROUGH 2014 ($ MILLIONS)115
TABLE 82 GLOBAL VEHICLE EXCIPIENT MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS)115
COATINGS116
MARKET SIZE116
TABLE 83 GLOBAL COATINGS EXCIPIENT MARKET BY TYPE, THROUGH 2014 ($ MILLIONS)116
TABLE 84 GLOBAL COATINGS EXCIPIENT MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS)117
DISINTEGRANTS118
MARKET SIZE118
TABLE 85 GLOBAL SUPERDISINTEGRANT EXCIPIENT MARKET BY TYPE, THROUGH 2014 ($ MILLIONS)118
TABLE 86 GLOBAL SUPERDISINTEGRANT EXCIPIENT MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS)119
FLAVORS119
MARKET SIZE119
TABLE 87 GLOBAL FLAVORS EXCIPIENT MARKET VALUE BY TYPE, THROUGH 2014 ($ MILLIONS)120
TABLE 88 GLOBAL FLAVORS EXCIPIENT MARKET VOLUME BY TYPE, THROUGH 2014 (LBS MILLIONS)120
TABLE 89 COMPARISON OF SEVERAL SWEETENERS TO SUCROSE (%)121
TONICITY AGENTS121
MARKET SIZE121
TABLE 90 GLOBAL TONICITY AGENT EXCIPIENT MARKET VALUE, THROUGH 2014 ($ MILLIONS)121
TABLE 91 GLOBAL TONICITY AGENT EXCIPIENT MARKET VOLUME, THROUGH 2014 (LBS MILLIONS)122
COLORANTS122
MARKET SIZE122
TABLE 92 GLOBAL COLORANTS EXCIPIENT MARKET BY TYPE, THROUGH 2014 ($ MILLIONS)123
TABLE 93 GLOBAL COLORANTS EXCIPIENT MARKET VOLUME BY TYPE, THROUGH 2014 (LBS MILLIONS)123
OTHER FUNCTIONAL USES123
MARKET SIZE123
TABLE 94 GLOBAL MARKET FOR OTHER FUNCTIONAL USES, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)124
PERFUMES124
BINDERS124
BUFFERS125
CHELATING AGENTS125
COMPRESSION AIDS125
EMULSIFIERS125
FOAM CONTROL AGENTS126
GLIDANTS126
HUMECTANTS126
LUBRICANTS126
PLASTICIZERS127
PRESERVATIVES127
THICKENERS127
DELIVERY SYSTEMS128
MARKET SIZE128
TABLE 95 GLOBAL EXCIPIENT DELIVERY SYSTEMS MARKET BY TYPE, THROUGH 2014 ($ MILLIONS)128
TABLE 96 GLOBAL EXCIPIENT DELIVERY SYSTEMS MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS)129
FIGURE 8 GLOBAL EXCIPIENT DELIVERY SYSTEMS MARKET BY TYPE, 2009 AND 2014 (%)129
FIGURE 8 (CONTINUED)130
INJECTION130
TABLE 97 TYPICAL INJECTION COMPOSITION (%)130
MARKET SIZE131
TABLE 98 GLOBAL EXCIPIENTS FOR INJECTIONS MARKET VALUE BY FUNCTION, THROUGH 2014 ($ MILLIONS)131
TABLE 99 GLOBAL EXCIPIENTS FOR INJECTIONS MARKET VOLUME BY FUNCTION, THROUGH 2014 (LBS MILLIONS)131
ORAL132
MARKET SIZE132
TABLE 100 GLOBAL EXCIPIENTS IN ORAL DELIVERY SYSTEMS MARKET BY TYPE, THROUGH 2014 ($ MILLIONS)133
TABLE 101 GLOBAL EXCIPIENTS IN ORAL DELIVERY SYSTEMS MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS)133
SOLIDS133
MARKET SIZE133
TABLE 102 GLOBAL EXCIPIENTS IN ORAL SOLID DELIVERY SYSTEMS MARKET BY TYPE, THROUGH 2014 ($ MILLIONS)134
TABLE 103 GLOBAL EXCIPIENTS IN ORAL SOLID DELIVERY SYSTEMS MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS)134
TABLETS134
TABLE 104 TYPICAL TABLET COMPOSITION135
MARKET SIZE136
TABLE 105 GLOBAL EXCIPIENTS IN TABLETS MARKET BY FUNCTION, THROUGH 2014 ($ MILLIONS)136
TABLE 106 GLOBAL EXCIPIENTS IN TABLETS MARKET BY FUNCTION, THROUGH 2014 (LBS MILLIONS)137
Market Size (Continued)138
CAPSULES139
MARKET SIZE139
TABLE 107 GLOBAL EXCIPIENTS IN GELATIN CAPSULES MARKET BY TYPE, THROUGH 2014 ($ MILLIONS)139
TABLE 108 GLOBAL EXCIPIENTS IN GELATIN CAPSULES MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS)140
HARD GELATIN CAPSULES140
TABLE 109 TYPICAL HARD GELATIN CAPSULE COMPOSITION140
Market Size141
TABLE 110 GLOBAL EXCIPIENTS IN HARD GELATIN CAPSULES MARKET VALUE BY FUNCTION, THROUGH 2014 ($ MILLIONS)141
TABLE 111 GLOBAL EXCIPIENTS IN HARD GELATIN CAPSULES MARKET VOLUME BY FUNCTION, THROUGH 2014 (LBS MILLIONS)141
SOFT GELATIN CAPSULES142
TABLE 112 TYPICAL SOFT GELATIN CAPSULE COMPOSITION142
Market Size142
TABLE 113 GLOBAL EXCIPIENTS IN SOFT GELATIN CAPSULES MARKET VALUE BY FUNCTION, THROUGH 2014 ($ MILLIONS)143
TABLE 114 GLOBAL EXCIPIENTS IN SOFT GELATIN CAPSULES MARKET VOLUME BY FUNCTION, THROUGH 2014 (LBS MILLIONS)143
LIQUIDS144
TABLE 115 TYPICAL LIQUID COMPOSITION (%)144
MARKET SIZE144
TABLE 116 GLOBAL EXCIPIENTS IN LIQUIDS MARKET VALUE BY FUNCTION, THROUGH 2014 ($ MILLIONS)145
TABLE 117 GLOBAL EXCIPIENTS IN LIQUIDS MARKET VOLUME BY FUNCTION, THROUGH 2014 (LBS MILLIONS)145
TOPICAL DELIVERY SYSTEMS146
MARKET SIZE146
TABLE 118 GLOBAL EXCIPIENTS IN TOPICAL DELIVERY SYSTEMS BY TYPE, THROUGH 2014 ($ MILLIONS)147
TABLE 119 GLOBAL EXCIPIENTS IN TOPICAL DELIVERY SYSTEMS BY TYPE, THROUGH 2014 (LBS MILLIONS)147
TABLE 120 TYPICAL OINTMENT COMPOSITION (%)148
CREAMS AND GELS148
TABLE 121 TYPICAL CREAM COMPOSITION (%)148
LOTIONS149
TABLE 122 TYPICAL TOPICAL LOTION COMPOSITION (%)149
DERMAL POWDERS150
SOLUTIONS150
ADVANCED DELIVERY SYSTEMS150
MARKET SIZE151
TABLE 123 GLOBAL EXCIPIENT ADVANCED DELIVERY SYSTEMS VALUE BY FUNCTION, THROUGH 2014 ($ MILLIONS)151
TABLE 124 GLOBAL EXCIPIENT ADVANCED DELIVERY SYSTEMS VOLUME BY FUNCTION, THROUGH 2014 (LBS MILLIONS)151
TABLE 124 (CONTINUED)152
CYCLODEXTRINS152
HYDROGELS152
IMPLANTS152
LIPOSOMES152
MICROPARTICLES153
MICROSPHERES153
NANOTECHNOLOGY (NANOPARTICLES)153
Nanotechnology (nanoparticles) (Continued)154
Nanotechnology (nanoparticles) (Continued)155
OSMOTIC PUMPS156
TRANSDERMAL156
TRANSMUCOSAL157
Buccal157
Tablets157
Capsules158
Lozenges158
Particles159
Thin Strips159
Inhalation160
Nasal160
Pulmonary160
Ophthalmic161
Otic162
Rectal162
Vaginal163
FINISHED PRODUCTS163
Market Size163
TABLE 125 GLOBAL EXCIPIENTS IN FINISHED PRODUCTS BY TYPE, THROUGH 2014 ($ MILLIONS)164
TABLE 126 GLOBAL EXCIPIENTS IN FINISHED PRODUCTS BY TYPE, THROUGH 2014 (LBS MILLIONS)165
PRESCRIPTION PRODUCTS165
MARKET SIZE165
TABLE 127 GLOBAL EXCIPIENTS IN RX DRUGS BY DELIVERY SYSTEM, THROUGH 2014 ($ MILLIONS)166
TABLE 128 GLOBAL EXCIPIENTS IN RX DRUGS BY DELIVERY SYSTEM, THROUGH 2014 (LBS MILLIONS)166
INJECTIONS166
Market Size167
TABLE 129 GLOBAL EXCIPIENTS IN INJECTED RX DRUGS BY TYPE, THROUGH 2014 ($ MILLIONS)167
TABLE 130 GLOBAL EXCIPIENTS IN INJECTED RX DRUGS BY TYPE, THROUGH 2014 (LBS MILLIONS)167
Small Molecule Drug Injections167
TABLE 131 GLOBAL EXCIPIENTS IN INJECTED RX SMALL MOLECULE DRUGS MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)168
Biologic Drug Injections168
TABLE 132 GLOBAL EXCIPIENTS IN INJECTED RX BIOLOGIC DRUGS MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)169
Protein Drugs169
Vaccines170
ORAL170
Market Size170
TABLE 133 GLOBAL EXCIPIENTS IN ORAL RX DRUGS MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)171
TOPICAL172
TABLE 134 GLOBAL EXCIPIENTS IN TOPICAL RX DRUGS MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)172
ADVANCED DRUG DELIVERY SYSTEMS172
TABLE 135 GLOBAL EXCIPIENTS IN ADVANCED SYSTEMS FOR RX DRUGS MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS)172
OVER-THE-COUNTER PRODUCTS173
MARKET SIZE173
TABLE 136 GLOBAL EXCIPIENTS IN OTC FINISHED PRODUCTS VALUE BY DELIVERY SYSTEM, THROUGH 2014 ($ MILLIONS)174
TABLE 137 GLOBAL EXCIPIENTS IN OTC FINISHED PRODUCTS VOLUME BY DELIVERY SYSTEM, THROUGH 2014 (LBS MILLIONS)174
FINISHED PRODUCT TRENDS174
PHARMACOGENOMICS175
COUNTERFEIT/STOLEN DRUGS175
INDUSTRY STRUCTURE175
INDUSTRY ENVIRONMENT176
MARKET INFLUENCES176
Pharmaceutical Industry Pressures176
General Health Trends177
Healthcare Industry177
Consumer Demographics178
IMPORTANT STRATEGIES178
R&D SPENDING178
CONSUMER ADVERTISING178
LEGISLATIVE LOBBYING179
CONSOLIDATION179
MULTIPLICITY OF DELIVERY SYSTEMS179
SUPPLIER LISTS179
QUALITY BY DESIGN180
MATERIAL CHOICE DECISIONS180
DRIVING FORCES180
MARKET SHARES181
FIGURE 9 SIMPLIFIED INDUSTRY STRUCTURE181
RAW MATERIAL SUPPLIERS181
Organic Chemical Suppliers182
Carbohydrate Suppliers182
Cellulose Suppliers182
FIGURE 10 MARKET SHARE OF MAJOR CELLULOSE SUPPLIERS, 2009 (%)182
FIGURE 10 (CONTINUED)183
Sugar Suppliers183
Actual Sugar Suppliers183
FIGURE 11 MARKET SHARE OF ACTUAL SUGAR EXCIPIENT SUPPLIERS, 2009 (%)183
FIGURE 11 (CONTINUED)184
Sugar Alcohols (Polyols)184
FIGURE 12 MARKET SHARE OF MAJOR SUGAR ALCOHOL (POLYOL) EXCIPIENT SUPPLIERS, 2009 (%)185
Artificial Sweeteners185
Starch Suppliers186
FIGURE 13 MARKET SHARE OF MAJOR STARCH EXCIPIENT SUPPLIERS, 2009 (%)186
FIGURE 13 (CONTINUED)187
Protein Suppliers187
FIGURE 14 MARKET SHARE OF MAJOR PROTEIN (GELATIN) EXCIPIENT SUPPLIERS, 2009 (%)188
Petrochemical Suppliers188
Glycol Suppliers189
FIGURE 15 MARKET SHARE OF MAJOR GLYCOL EXCIPIENT SUPPLIERS, 2009 (%)189
PVP Suppliers190
Mineral Hydrocarbon Suppliers190
Acrylic Suppliers190
Oleochemical Suppliers190
FIGURE 16 MARKET SHARE OF MAJOR OLEOCHEMICAL EXCIPIENT SUPPLIERS, 2009 (%)191
Inorganic Chemical Suppliers192
Calcium Salts Suppliers192
FIGURE 17 MARKET SHARE OF MAJOR CALCIUM-BASED EXCIPIENT SUPPLIERS, 2009 (%)192
Halite Suppliers193
FIGURE 18 MARKET SHARE OF MAJOR HALITE EXCIPIENT SUPPLIERS, 2009 (%)193
FIGURE 18 (CONTINUED)194
Metal Oxide Suppliers194
FIGURE 19 MARKET SHARE OF MAJOR METAL OXIDE EXCIPIENT SUPPLIERS, 2009 (%)194
FIGURE 19 (CONTINUED)195
Silicate Suppliers195
USP Water Suppliers195
FIGURE 20 MARKET SHARE OF MAJOR USP WATER SUPPLIERS, 2009 (%)196
DISTRIBUTORS/MODIFIERS197
Distributors197
TABLE 138 DISTRIBUTOR CATEGORIES197
Brokers198
Import/Export Traders198
Chemical Stocking/Repacking198
Modifiers198
TABLE 139 CATEGORIES OF MODIFIERS199
Contract Development Organizations199
Contract Coaters199
END USERS199
TABLE 140 CATEGORIES OF MODIFIERS200
Drug Companies200
Contract Formulators200
Retail and Hospital Pharmacies201
Pharmacy Colleges and Other Academic Institutions201
Other End Users201
INTERNATIONAL ASPECTS202
Americas202
Europe202
Asia/Pacific Rim203
Others204
Chapter-6: COMPANY PROFILES
COMPANY PROFILES205
COMPANY PROFILES (CONTINUED)206
ABBOTT LABORATORIES207
ADAMAS PHARMACEUTICALS, INC.208
ADM (ARCHER DANIELS MIDLAND CO.)208
AKZO NOBEL N.V. (ALSO ICI AND NATIONAL STARCH)209
AMERICHEM PHARMACEUTICAL CORP.210
AMTEX (QUIMICA AMTEX MEXICO)210
ARLA FOODS A.M.B.A.211
ASAHI KASEI CORP. (ASAHI KASEI PHARMA)211
ASHLAND AQUALON FUNCTIONAL INGREDIENTS (AAFI)212
ASSOCIATED BRITISH FOODS (ABF)213
BANNER PHARMACAPS, INC.214
BASF A.G.215
BAXTER INTERNATIONAL, INC.216
BLANVER FARMOQUIMICA, LTDA.217
BLUE REFERENCE217
BRENNTAG GROUP218
BUDENHEIM218
CABOT CORP.219
CALUMET SPECIALTY PRODUCTS PARTNERS, LP (PENRECO)219
CARGILL, INC.220
CHARLES TENNANT & CO., LTD.221
CHR. HANSEN A/S221
COGNIS DEUTSCHLAND GMBH & CO. K.G.222
COLORCON, INC.223
CORN PRODUCTS INTERNATIONAL, INC.224
COSMETIC SPECIALTIES, INC.225
CRISTAL GLOBAL (NATIONAL TITANIUM DIOXIDE CO., LTD.)225
CRODA INTERNATIONAL, PLC225
CRODA INTERNATIONAL, PLC (CONTINUED)226
CSL BEHRING, LLC227
CSM N.V.227
CTD, INC.228
CYDEX PHARMACEUTICALS, INC.228
DANISCO A/S229
DOW CHEMICAL CO.230
DOW CHEMICAL CO. (CONTINUED)231
DUPONT (E.I. DU PONT DE NEMOURS & CO.)232
EASTMAN CHEMICAL CO.233
EM2 SOLUTIONS, INC.234
EURAND234
EVONIK DEGUSSA GMBH (EVONIK INDUSTRIES AG)234
FERRO CORP.235
FIBROGEN, INC.236
FINNBRIT CONSULTING236
FLAVORX INC.236
FMC CORP.237
FMC CORP. (CONTINUED)238
FONTERRA CO-OPERATIVE GROUP, LTD.239
FOREMOST FARMS USA240
FUJI HEALTH SCIENCE, INC. (FUJI CHEMICAL INDUSTRY CO., LTD.)241
GATTEFOSSE GROUP241
GE HEALTHCARE242
GELITA AG242
GENERAL CHEMICAL (GENCHEM)243
GLATT GMBH (GLATT AIR TECHNIQUES, INC.)243
GRAIN PROCESSING CORP.243
GRIFOLS S.A. (LABORATORIOS GRIFOLS S.A.)244
GTC BIOTHERAPEUTICS, INC.245
HILMAR CHEESE CO. (HILMAR INGREDIENTS)245
HOLLANDSE MELKSUIKERFABRIEK245
IMERYS246
INTERNATIONAL SPECIALTY PRODUCTS (ISP)246
J.M. HUBER CORP. (CP KELCO AND HUBER ENGINEERED MATERIALS)247
CP KELCO247
HUBER ENGINEERED MATERIALS247
JOHNSON & JOHNSON PHARMACEUTICAL R&D248
JOST CHEMICAL CO.249
JRS PHARMA (AND J. RETTENMAIER)249
KEMIRA OYJ250
KOSTER KEUNEN HOLLAND B.V.251
KRAFT FOODS ATLANTIC GELATIN251
KRONOS WORLDWIDE, INC.251
LANXESS A.G.252
LUBRIZOL CORP.252
LYONDELLBASELL INDUSTRIES252
MALLINCKRODT BAKER, INC. (COVIDIEN)253
MEGGLE GMBH254
MERCK KGAA (AND EMD)255
MICRO-MACINAZIONE S.A.256
MINERALS TECHNOLOGIES, INC. (SPECIALTY MINERALS, INC.)256
MINGTAI CHEMICAL CO., LTD.257
MITSUBISHI CHEMICAL PERFORMANCE POLYMERS, INC.257
MUTCHLER, INC. PHARMACEUTICAL INGREDIENTS258
NITTA GELATIN, INC.258
NORDZUCKER AG259
NOVOZYMES A/S259
NUSIL TECHNOLOGY260
NUTRASWEET CO.260
OMYA A.G.261
PARAYTEC, LTD.262
PERRIGO CO.262
PFIZER, INC.262
P&G CHEMICALS263
PHARMACEUTICAL-TECHNOLOGY.COM263
PMC GLOBAL, INC.263
PURDUE PHARMA, LP264
QUALITY SYSTEMS DESIGN, INC.264
RHODIA S.A.265
RIO TINTO, PLC265
ROQUETTE FRERES266
ROUSSELOT S.A.S.267
ROYAL FRIESLANDCAMPINA N.V.268
R.T. VANDERBILT COMPANY, INC.269
RUGER CHEMICAL CO., INC.269
SASOL, LTD. ADR270
SCHERING-PLOUGH CORP.270
SENSIENT TECHNOLOGIES CORP.271
SEPPIC S.A.271
SHEFFIELD PHARMA INGREDIENTS272
SHELL CHEMICALS (ROYAL DUTCH SHELL)273
SHIN-ETSU CHEMICAL CO., LTD.273
SOLVAY S.A.274
SPI PHARMA, INC.275
STEPAN CO.275
STERLING BIOTECH, LTD.276
TABLETS & CAPSULES276
TAKEHARA CHEMICAL INDUSTRIAL CO., LTD.277
TALECRIS BIOTHERAPEUTICS, INC.277
TATE & LYLE, PLC277
TATE & LYLE, PLC (CONTINUED)278
TESSENDERLO GROUP (PB GELATINS)279
TOMITA PHARMACEUTICAL CO., LTD.279
UNIVAR N.V. (AND UNIVAR USA)280
USG CORP.280
VALIDATION & ENGINEERING GROUP (VEG)280
VERTELLUS PERFORMANCE MATERIALS, INC. (VPMI)281
WACKER FINE CHEMICALS (WACKER CHEMIE)281
WEI MING PHARMACEUTICAL MFG. CO., LTD.282
WEISHARDT GROUP282
W.R. GRACE & CO.283
