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Vaccine Partnering Terms and Agreements

  • February 2015
  • -
  • Currentpartnering
  • -
  • 1394 pages

The Vaccine Partnering Terms and Agreements report provides comprehensive understanding and unprecedented access to the vaccine partnering deals and agreements entered into by the worlds leading healthcare companies.

Trends in vaccine and adjuvant partnering deals
Deal terms analysis
Partnering agreement structure
Partnering contract documents
Top deals by value
Most active dealmakers
Average deal terms for vaccines

The report provides a detailed understanding and analysis of how and why companies enter vaccine partnering deals. The majority of deals are discovery or development stage whereby the licensee obtains a right or an option right to license the licensors vaccine technology. These deals tend to be multicomponent, starting with collaborative R&D, and commercialization of outcomes. The report also includes adjuvant deals and alliances.

Understanding the flexibility of a prospective partner’s negotiated deals terms provides critical insight into the negotiation process in terms of what you can expect to achieve during the negotiation of terms. Whilst many smaller companies will be seeking details of the payments clauses, the devil is in the detail in terms of how payments are triggered – contract documents provide this insight where press releases do not.

This report contains over 1,000 links to online copies of actual vaccine deals along with contract documents where available as submitted to the Securities Exchange Commission by companies and their partners. Contract documents provide the answers to numerous questions about a prospective partner’s flexibility on a wide range of important issues, many of which will have a significant impact on each party’s ability to derive value from the deal.

The initial chapters of this report provide an orientation of vaccine dealmaking and business activities. Chapter 1 provides an introduction to the report, whilst chapter 2 provides an overview of the trends in vaccine dealmaking since 2009, including details of average headline, upfront, milestone and royalty terms.

Chapter 3 provides a review of the leading vaccine deals since 2009. Deals are listed by headline value, signed by big pharma, big biotech, and most active of all biopharma companies. Where the deal has an agreement contract published at the SEC a link provides online access to the contract.

Chapter 4 provides a comprehensive listing of the top 50 bigpharma companies with a brief summary followed by a comprehensive listing of vaccine deals, as well as contract documents available in the public domain. Where available, each deal title links via Weblink to an online version of the actual contract document, providing easy access to each contract document on demand.

Chapter 5 provides a comprehensive listing of the top big biotech companies with a brief summary followed by a comprehensive listing of vaccine deals, as well as contract documents available in the public domain. Where available, each deal title links via Weblink to an online version of the actual contract document, providing easy access to each contract document on demand.

Chapter 6 provides a comprehensive and detailed review of vaccine partnering deals signed and announced since January 2009, where a contract document is available in the public domain. The chapter is organized by company A-Z, stage of development at signing, deal type (collaborative R&D, co-promotion, licensing etc) and specific therapy focus. Each deal title links via Weblink to an online version of the deal record and where available, the contract document, providing easy access to each contract document on demand.

Chapter 7 provides a comprehensive and detailed review of vaccine partnering deals signed and announced since January 2009. The chapter is organized by specific vaccine and adjuvant technology type. Where contract available, the deal links via Weblink to an online version of the deal record providing easy access to each contract document on demand.

The report also includes numerous tables and figures that illustrate the trends and activities in vaccine partnering and dealmaking since 2009.

In conclusion, this report provides everything a prospective dealmaker needs to know about partnering in the research, development and commercialization of vaccine technologies and products.

In addition, a comprehensive appendix is provided organized by vaccine partnering company A-Z, stage of development, theray area and deal type definitions. Each deal title links via Weblink to an online version of the deal record and where available, the contract document, providing easy access to each contract document on demand.

In conclusion, this report provides everything a prospective dealmaker needs to know about partnering in the research, development and commercialization of vaccine technologies and products.
Vaccine Partnering Terms and Agreements is intended to provide the reader with an in-depth understanding and access to vaccine trends and structure of deals entered into by leading companies worldwide.

Vaccine Partnering Terms and Agreements includes:

Trends in vaccine dealmaking in the biopharma industry since 2009
Analysis of vaccine deal structure
Access to headline, upfront, milestone and royalty data
Case studies of real-life vaccine deals
Access to over 1,000 vaccine deal documents
The leading vaccine deals by value since 2009
Most active vaccine dealmakers since 2009
The leading vaccine partnering resources

In Vaccine Partnering Terms and Agreements, the available contracts are listed by:

Company A-Z
Headline value
Stage of development at signing
Deal component type
Therapy target
Specific technology type

Each deal title links via weblink to an online version of the deal record and where available, the contract document, providing easy access to each contract document on demand.

The Vaccine Partnering Terms and Agreements report provides comprehensive access to available deals and contract documents for over 880 vaccine deals. Analyzing actual contract agreements allows assessment of the following:

What are the precise vaccine rights granted or optioned?
What is actually granted by the agreement to the partner company?
What exclusivity is granted?
What is the payment structure for the deal?
How are sales and payments audited?
What is the deal term?
How are the key terms of the agreement defined?
How are IPRs handled and owned?
Who is responsible for commercialization?
Who is responsible for development, supply, and manufacture?
How is confidentiality and publication managed?
How are disputes to be resolved?
Under what conditions can the deal be terminated?
What happens when there is a change of ownership?
What sublicensing and subcontracting provisions have been agreed?
Which boilerplate clauses does the company insist upon?
Which boilerplate clauses appear to differ from partner to partner or deal type to deal type?
Which jurisdiction does the company insist upon for agreement law?

Table Of Contents

Vaccine Partnering Terms and Agreements
Executive Summary

Chapter 1 - Introduction

Chapter 2 - Trends in vaccine dealmaking

2.1. Introduction
2.2. Vaccine partnering over the years
2.3. Big pharma vaccine dealmaking activity
2.4. Big biotech vaccine dealmaking activity
2.5. Most active in vaccine partnering
2.6. Vaccine partnering by deal type
2.7. Vaccine partnering by disease type
2.8. Average deal terms for vaccine partnering
2.8.1 Vaccine deals with headline values
2.8.2 Vaccine deals with upfront payments
2.8.3 Vaccine deals with milestone payments
2.8.4 Vaccine deals with royalty rates
2.9. The anatomy of vaccine partnering
2.9. The anatomy of a vaccine deal
2.9. a. Case study 1: Stemline Therapeutics- University of Pittsburgh: March 2012
2.9.b. Case study 2: Agenus Bio- NewVac: December 2011

Chapter 3 - Leading vaccine deals

3.1. Introduction
3.2. Top vaccine deals by value
3.3. Top vaccine deals involving big pharma
3.4. Top vaccine deals involving big biotech

Chapter 4 - Big pharma vaccine deals

4.1. Introduction
4.2. How to use big pharma vaccine partnering deals
4.3. Big pharma vaccine partnering company profiles
4.3. Big pharma vaccine partnering company profiles

Chapter 5 - Big biotech vaccine deals

5.1. Introduction
5.2. How to use big biotech partnering deals
5.3. Big biotech vaccine partnering company profiles

Chapter 6 - Vaccine contracts dealmaking directory

6.1. Introduction
6.2. Company A-Z
6.3. By stage of development
6.4. By deal type
6.5. By therapy area

Chapter 7 - Vaccine dealmaking directory by technology type

7.2. Deals by technology type
Vaccines
Adjuvant

Chapter 8 - Vaccine partnering resource center

8.1. Online vaccine partnering
8.2. Vaccine partnering events
8.3. Further reading on vaccine dealmaking

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Table of figures

Figure 1: Vaccine partnering since 2009
Figure 1: Vaccine partnering since 2009
Figure 2: Big pharma - top 50 - vaccine deals 2009 to 2014
Figure 3: Big pharma vaccine deal frequency - 2009 to 2014
Figure 4: Big biotech - vaccine deals 2009 to 2014
Figure 5: Big biotech vaccine deal frequency - 2009 to 2014
Figure 6: Active vaccine dealmaking activity- 2009 to 2014
Figure 7: Vaccine partnering by deal type since 2009
Figure 8: Vaccine partnering by disease type since 2009
Figure 9: Vaccine partnering by infectives target since 2009
Figure 10: Vaccine partnering by oncology target since 2009
Figure 11: Vaccine deals with a headline value by year- 2014
Figure 12: Vaccine deals with a headline value by year- 2013
Figure 13: Vaccine deals with a headline value by year- 2012
Figure 14: Vaccine deals with a headline value by year- 2011
Figure 15: Vaccine deals with a headline value by year- 2010
Figure 161: Vaccine deals with a headline value by year- 2009
Figure 17: Summary median headline value by year, 2009-2014
Figure 18: Vaccine deals with an upfront value by year- 2013
Figure 19: Vaccine deals with an upfront value by year- 2012
Figure 20: Vaccine deals with an upfront value by year- 2011
Figure 21: Vaccine deals with an upfront value by year- 2010
Figure 22: Vaccine deals with an upfront value by year- 2009
Figure 23: Summary median upfront value by year, 2009-2014
Figure 24: Vaccine deals with a milestone value by year- 2013
Figure 25: Vaccine deals with a milestone value by year- 2012
Figure 26: Vaccine deals with a milestone value by year- 2011
Figure 27: Vaccine deals with a milestone value by year- 2010
Figure 28: Vaccine deals with a milestone value by year- 2009
Figure 29: Vaccine deals with a royalty rate value by year- 2014
Figure 30: Vaccine deals with a royalty rate value by year- 2013
Figure 31: Vaccine deals with a royalty rate value by year- 2012
Figure 32: Vaccine deals with a royalty rate value by year- 2011
Figure 33: Vaccine deals with a royalty rate value by year- 2010
Figure 34: Vaccine deals with a royalty rate value by year- 2009
Figure 35: Summary median royalty rate by year, 2009-2014
Figure 36: Components of the typical vaccine deal structure
Figure 37: Top vaccine deals by value since 2009
Figure 38: Top vaccine deals signed by big pharma value since 2009
Figure 39: Top vaccine deals signed by big biotech value since 2009
Figure 40: Online partnering resources
Figure 41: Forthcoming partnering events

See accompanying volume for appendices

Appendix

Appendix 1- Vaccine dealmaking- by company A-Z
Appendix 2- Vaccine dealmaking- by deal type
Appendix 3- Vaccine dealmaking- by stage of development
Appendix 4- Vaccine dealmaking- by therapy area

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