Highlights

The global intravascular ultrasound technology (IVUS) products market reached $483.7 million in 2012. The market is expected to reach $702 million in 2017 for a compound annual growth rate (CAGR) of 7.7%. The Japanese IVUS products market as a segment was valued at $176.1 million in 2012. It is expected to reach $257.4 million in 2017, a CAGR of 7.9%. The U.S. IVUS products market as a segment was valued at $168.7 million in 2012. It is expected to reach $238 million in 2017, a CAGR of 7.1%.

Introduction & Scope

This study measures, forecasts and segments the intravascular ultrasound technology (IVUS) market on the basis of products, applications and end users. Geographic analyses of all these markets are also provided in the study. The key products captured in the study include: IVUS consoles (including integrated and cart version consoles). IVUS catheters (including mechanical/rotatory and static electric/phased array catheters). Accessories (pullback devices, guidewires and introducer sheaths, and other accessories). Software. Services. The key applications covered in the study include the following. Coronary applications Diagnostic applications (including lesion characterization/decision on PCI sizing and strategy; assessment of angiographically indeterminate lesions or lesion significance; and other coronary IVUS diagnostic applications). Interventional applications (including guidance for angioplasty; guidance for plaque modification; stent thrombosis and restenosis; and other interventional clinical coronary applications). Research (including drug discovery and development; angioplasty/stents evaluation; atherosclerosis process and others). Noncoronary/peripheral applications (including diagnostic, interventional and research applications). The key end users captured in the study include the following. Hospitals. Stand-alone labs. Research centers and organizations (research work conducted by academic or medical schools is covered in this section). Commercial organizations. The key geographic regions according to which the markets are segmented include: Japan. U.S. Europe. Asia and ROW.

STUDY GOALS AND OBJECTIVES

The goal of this study is to provide industry participants insights on the IVUS market scenario, both in terms of quantitative as well as qualitative data, which could help them to gain market insights in order to develop business/growth strategies, analyze their position in the current market scenario and make key business decisions in the IVUS market. In particular, the objectives of the study are the following. To provide comprehensive analysis of IVUS products, applications and end-user segments. To identify the market dynamics of each key market and the relevant business impact thereof. To provide market forecasting of products, applications and end users by their respective segments and by the geographic regions mentioned above. To report and analyze key market developments. To highlight and analyze market trends, drivers, restraints and opportunities. To provide key recommendations. To analyze each key geographic region listed above and understand its drivers and restraints. To provide the market shares of key market players, and analyze the competitive scenario of the market.

REASONS FOR DOING THE STUDY

Intravascular ultrasound (IVUS) is a rapidly growing medical imaging technology, which holds immense potential pertaining to its ability to address unmet requirements in the earlier detection and intervention of coronary artery diseases. Moreover, the popularity of this technology has surged due to its proven advantages (as indicated by some international clinical studies) over traditional angiography. In addition to this, an aging population and rising chronic disease (such as cardiac disease) population is also fueling the market’s growth. However, the high cost of IVUS devices/products coupled with the growing need of cost-effective treatment worldwide is restricting the potential market growth. On the other side, different reimbursement scenarios for such devices depict varying degrees of penetration of this technology worldwide. This report presents such issues that are driving and constraining the market growth and probable solutions that can address such concerns. This report also highlights key market strategies, trends and recommendations in addition to providing the quantitative assessment of the market that can help manufacturers and suppliers understand the growth potential of different market segments.

SCOPE OF REPORT

This report includes only those products, applications and end users that are listed above, and segments the global market by four regions as listed above. The scope of the report includes the following. Key market analysis. Strategic recommendations. Market dynamics (drivers, restraints and opportunities). Forecasted market estimation for 2012 through 2017. Competitive developments and landscape. Geographical analysis. Market share of leading market players. Profiles of key market players. Patents.

INTENDED AUDIENCE

The key audience for this study includes: IVUS product developers and manufacturers. IVUS market start-ups. Academic and commercial research organizations. Consulting firms. Medical imaging market information database developers. This report will enable the audience to understand and gain insights of the current and changing market scenario. The data provided can help users understand which market segments (products, applications and end users) are expected to growth at higher rates, factors driving growth, factors limiting the growth, key opportunity areas and so on.

INFORMATION SOURCES AND METHODOLOGY

Because of the nature of the markets involved in this report, the markets were assessed in the top-down method. The content provided in this report including market numbers and forecasts was prepared based on both primary and secondary research methodologies. Market dynamics, qualitative information and views of industry participants were also taken into consideration while forecasting and measuring the market values. Historic and base numbers were derived from primary and secondary methodology. Macro markets were further divided into micro markets in consultation with views of different industry participants. The average of the range of the estimates gathered from primary research was taken, and later validated from, secondary and primary sources. Similarly, data on PCI numbers, IVUS procedures and IVUS penetration rates were gathered both from primary and secondary research. The primary research included interviews and discussions with key industry participants, key opinion leaders and some subject matter experts including healthcare professionals or technicians (such as nurses, doctors, lab technicians). Secondary data were collected from free sources such as Google search, company websites, industry reports and paid sources such as Key notes, Factiva, LexisNexis, etc. In this market study, IVUS use is segmented into three sections at the micro level: research, diagnostics and intervention. Some of the applications categorized under the intervention section may seem to be part of diagnostics; thus, such categories named in this market study are subject to the definitions of each market segment of diagnostics and intervention categories.

Table Of Contents

CHAPTER 1 INTRODUCTION 2
INTRODUCTION 2
STUDY GOALS AND OBJECTIVES 3
REASONS FOR DOING THE STUDY 3
SCOPE OF REPORT 3
INTENDED AUDIENCE 4
INFORMATION SOURCES AND METHODOLOGY 4
ANALYST CREDENTIALS 5
RELATED BCC REPORTS 5
BCC ONLINE SERVICES 5
DISCLAIMER 5
CHAPTER 2 SUMMARY 7
SUMMARY TABLE GLOBAL IVUS PRODUCTS MARKET BY REGION, THROUGH 2017 ($
MILLIONS) 7
SUMMARY FIGURE GLOBAL IVUS PRODUCTS MARKET BY REGION, 2010-2017 ($
MILLIONS) 7
CHAPTER 3 OVERVIEW 10
IVUS TECHNOLOGY EVOLUTION AND INDUSTRY LIFE CYCLE STAGE 10
IVUS INDUSTRY IN JAPAN - RELATIVELY MATURE MARKET 10
IVUS INDUSTRY WORLDWIDE (EXCEPT JAPAN) - GROWING PHASE 11
IVUS PRODUCT MARKET ANALYSIS 11
FIGURE 1 MARKET SHARE OF KEY PRODUCTS IN IVUS MARKET, 2012 (%) 11
PRODUCT DIFFERENTIATION - IVUS IMAGING SYSTEMS 12
IVUS KEY APPLICATIONS MARKET ANALYSIS 13
FIGURE 2 KEY APPLICATIONS AREAS OF IVUS VERSUS TOTAL APPLICATION,
2010-2017 ($ MILLIONS) 13
IVUS END-USER MARKET ANALYSIS 14
FIGURE 3 MARKET SHARE OF KEY END USERS IN IVUS MARKET, 2012 (%) 14
REGULATORY ENVIRONMENT 15
MARKET DYNAMICS 16
DRIVERS 16
Emergence of Favorable and Positive IVUS Clinical Data 16
Competitive Edge of IVUS over Angiography 17
Technology Advancements, Product Developments and Innovations 17
Collaborations of Some Market Players with Leading Laboratory
Suppliers 19
Growing and Expanding Applications Coupled with a Rise in Stent
Deployments 19
Growing Patient Population, Increasing Burden of Diseases and Rise
in Global Aging Population 20
Lower Penetration of IVUS Worldwide and Declining PCI Rate 20
TABLE 1 APPROXIMATE GLOBAL IVUS PENETRATION IN PCI 2012, BY REGION
(THOUSANDS/%) 21
RESTRAINTS AND CHALLENGES 21
Reimbursement Issues 21
High Cost of Products and Low Average Selling Prices 22
Two-Way Growing Competition 22
Stringent Regulatory Environment 23
Other Restraints 23
OPPORTUNITIES 24
Products 24
Applications and Geographic Expansion 24
IVUS VERSUS OTHER COMPETITIVE TECHNOLOGIES 25
IVUS VS OPTICAL COHERENCE TOMOGRAPHY (OCT) 25
IVUS VS FRACTIONAL FLOW RESERVE (FFR) 26
COST BENEFIT ANALYSIS 26
MARKET TRENDS 27
COMPETITIVE SCENARIO AND MARKET SHARE ANALYSIS 28
FIGURE 4 GLOBAL IVUS MARKET SHARE BY KEY MARKET PLAYERS, 2012 (%) 29
FIGURE 5 JAPANESE IVUS MARKET SHARE BY KEY MARKET PLAYERS, 2012 (%) 29
FIGURE 6 U.S. IVUS MARKET SHARE BY KEY MARKET PLAYERS, 2012 (%) 30
IVUS MARKET: THE ROAD AHEAD 30
RECOMMENDATIONS/STRATEGIES 31
CONSIDER MAKING EFFORTS TOWARD BETTER IMAGE INTERPRETATION 32
EXPLORE WAYS TO DEVELOP COMPETITIVE EDGE OVER COMPETING
TECHNOLOGIES IN THEIR OBSTACLE AREAS 32
INVESTIGATE THE TRAINING REQUIREMENTS OF DIFFERENT REGIONS
REGULARLY AND CONSIDER DEVELOPING TRAINING SERVICES
ACCORDINGLY
32
CONSIDER INVESTMENTS IN EMERGING ECONOMIES 32
FOCUS ON DEVELOPING MULTIMODALITY SYSTEMS 33
EXPLORE MARKETING AND PRODUCT DEVELOPMENT COLLABORATIONS 33
EVALUATE THE OPTIMAL SALES MODEL FOR RELATIVELY MORE POTENTIAL
REGIONS 33
FOCUS MORE ON DISSEMINATING IVUS BENEFITS THROUGH MULTIPLE
CHANNELS 34
CONSIDER INPUT OF KEY STAKEHOLDERS WHILE DEVELOPING PRODUCTS 34
PATENT ANALYSIS 34
FIGURE 7 PATENT ANALYSIS BY REGION, 2010-FEBRUARY 2013 (%) 34
CHAPTER 4 PRODUCTS MARKET 37
INTRODUCTION 37
DRIVERS 37
MARKET SCENARIO/INSIGHTS 37
TABLE 2 GLOBAL IVUS MARKET BY PRODUCTS, THROUGH 2017 ($ MILLIONS) 38
TABLE 3 GLOBAL IVUS PRODUCTS MARKET BY REGION, THROUGH 2017 ($
MILLIONS) 39
IVUS CONSOLES 39
KEY COMPETITIVE FACTORS 39
TABLE 4 GLOBAL IVUS CONSOLES MARKET BY TYPE OF CONSOLE, THROUGH 2017
($ MILLIONS) 40
TABLE 5 GLOBAL IVUS CONSOLES MARKET BY REGION, THROUGH 2017 ($
MILLIONS) 40
DRIVERS, RESTRAINTS AND CHALLENGES 40
INTEGRATED VERSION - IVUS CONSOLES 41
TABLE 6 GLOBAL IVUS INTEGRATED CONSOLES MARKET BY REGION, THROUGH
2017 ($ MILLIONS) 42
CART IVUS CONSOLES 42
TABLE 7 GLOBAL CART IVUS CONSOLES MARKET BY REGION, THROUGH 2017 ($
MILLIONS) 43
IVUS CATHETERS MARKET 43
DRIVERS AND RESTRAINTS 45
KEY COMPETITIVE FACTORS 45
TABLE 8 GLOBAL IVUS CATHETERS MARKET BY TYPE OF CATHETER, THROUGH
2017 ($ MILLIONS) 46
TABLE 9 GLOBAL IVUS CATHETERS MARKET BY REGION, THROUGH 2017 ($
MILLIONS) 46
MECHANICAL (ROTATORY) CATHETERS 46
TABLE 10 GLOBAL IVUS MECHANICAL ROTATORY CATHETERS MARKET BY REGION,
THROUGH 2017 ($ MILLIONS) 47
STATIC ELECTRONIC (PHASED ARRAY) CATHETERS 47
TABLE 11 GLOBAL IVUS STATIC ELECTRONIC (PHASED ARRAY) CATHETERS
MARKET BY REGION, THROUGH 2017 ($ MILLIONS) 48
ACCESSORIES MARKET 48
TABLE 12 GLOBAL IVUS ACCESSORIES MARKET BY TYPE OF ACCESSORY,
THROUGH 2017 ($ MILLIONS) 48
TABLE 13 GLOBAL IVUS ACCESSORIES MARKET BY REGION THROUGH 2017 ($
MILLIONS) 49
PULLBACK DEVICES 49
GUIDEWIRES AND INTRODUCER SHEATH 50
OTHER DEVICES 50
SOFTWARE 50
DRIVERS 51
TABLE 14 GLOBAL IVUS SOFTWARE MARKET BY REGION, THROUGH 2017 ($
MILLIONS) 52
SERVICES 52
TABLE 15 GLOBAL IVUS SERVICES MARKET BY REGION, THROUGH 2017 ($
MILLIONS) 53
CHAPTER 5 END-USER MARKET 55
INTRODUCTION 55
DRIVERS AND RESTRAINTS 55
TABLE 16 GLOBAL IVUS MARKET BY END USERS, THROUGH 2017 ($ MILLIONS) 56
TABLE 17 GLOBAL IVUS END-USER MARKET BY REGION, THROUGH 2017 ($
MILLIONS) 56
HOSPITALS 56
DRIVERS AND RESTRAINTS 57
TABLE 18 IVUS HOSPITAL END-USER MARKET BY REGION, THROUGH 2017 ($
MILLIONS) 58
STAND-ALONE LABS 58
TABLE 19 GLOBAL IVUS STAND-ALONE LABS END-USER MARKET BY REGION,
THROUGH 2017 ($ MILLIONS) 58
RESEARCH CENTERS/ORGANIZATIONS 59
TABLE 20 IVUS RESEARCH CENTERS AND ORGANIZATIONS END-USER MARKET BY
REGION, THROUGH 2017 ($ MILLIONS) 60
COMMERCIAL ORGANIZATIONS 60
TABLE 21 IVUS COMMERCIAL ORGANIZATIONS END-USER MARKET BY REGION,
THROUGH 2017 ($ MILLIONS) 61
CHAPTER 6 APPLICATION MARKET 63
INTRODUCTION 63
TABLE 22 GLOBAL IVUS APPLICATION MARKET BY TYPES OF APPLICATIONS,
THROUGH 2017 ($ MILLIONS) 63
TABLE 23 GLOBAL IVUS APPLICATIONS MARKET BY REGION, THROUGH 2017 ($
MILLIONS) 63
DRIVERS AND RESTRAINTS 64
CORONARY APPLICATIONS MARKET 64
TABLE 24 GLOBAL IVUS CORONARY APPLICATION MARKET BY TYPE OF
APPLICATION, THROUGH 2017 ($ MILLIONS) 65
TABLE 25 GLOBAL IVUS CORONARY APPLICATIONS MARKET BY REGION, THROUGH
2017 ($ MILLIONS) 65
IVUS CORONARY DIAGNOSTIC MARKET 65
TABLE 26 GLOBAL IVUS CORONARY DIAGNOSTIC APPLICATIONS MARKET BY TYPE
OF APPLICATION, THROUGH 2017 ($ MILLIONS) 66
TABLE 27 GLOBAL IVUS CORONARY DIAGNOSTIC APPLICATIONS MARKET BY
REGION, THROUGH 2017 ($ MILLIONS) 66
Lesion Characterization/Decision on PCI Sizing and Strategy 67
TABLE 28 GLOBAL LESION CHARACTERIZATION/DECISION ON PCI SIZING AND
STRATEGY IVUS CORONARY INTERVENTION APPLICATIONS MARKET BY REGION,
THROUGH 2017 ($ MILLIONS)
67
Assessment of Angiographically Indeterminate Lesions or Lesion
Significance 68
TABLE 29 GLOBAL ANGIOGRAPHICALLY INTERMEDIATE LESIONS/LESION
SIGNIFICANCE IVUS CORONARY DIAGNOSTIC APPLICATIONS MARKET BY REGION,
THROUGH 2017 ($ MILLIONS)
69
Other Coronary IVUS Diagnostic Applications 69
TABLE 30 GLOBAL OTHER IVUS CORONARY DIAGNOSTIC APPLICATIONS MARKET
BY REGION, THROUGH 2017 ($ MILLIONS) 70
IVUS CORONARY INTERVENTION MARKET 70
TABLE 31 GLOBAL IVUS CORONARY INTERVENTIONS APPLICATIONS MARKET BY
TYPE OF APPLICATION, THROUGH 2017 ($ MILLIONS) 71
TABLE 32 GLOBAL IVUS CORONARY INTERVENTIONS APPLICATIONS MARKET BY
REGION, THROUGH 2017 ($ MILLIONS) 71
Guidance for Angioplasty 71
TABLE 33 GLOBAL GUIDANCE FOR ANGIOPLASTY IVUS CORONARY INTERVENTION
APPLICATIONS MARKET BY REGION, THROUGH 2017 ($ MILLIONS) 72
Guidance for Plaque Modification 72
TABLE 34 GLOBAL GUIDANCE FOR PLAQUE MODIFICATION IVUS CORONARY
INTERVENTION APPLICATIONS MARKET BY REGION, THROUGH 2017 ($ MILLIONS) 73
Stent Thrombosis and Restenosis 73
TABLE 35 GLOBAL STENT THROMBOSIS AND RESTENOSIS IVUS CORONARY
INTERVENTION APPLICATIONS MARKET BY REGION, THROUGH 2017 ($ MILLIONS) 74
Other Coronary Interventional Applications 75
TABLE 36 GLOBAL OTHER IVUS CORONARY INTERVENTION APPLICATIONS MARKET
BY REGION, THROUGH 2017 ($ MILLIONS) 75
IVUS CORONARY RESEARCH MARKET 75
TABLE 37 GLOBAL IVUS CORONARY RESEARCH APPLICATIONS MARKET BY TYPE OF
AREA OF RESEARCH, THROUGH 2017 ($ MILLIONS) 76
TABLE 38 GLOBAL IVUS CORONARY RESEARCH APPLICATIONS MARKET BY REGION,
THROUGH 2017 ($ MILLIONS) 76
Drug Discovery and Development 76
TABLE 39 GLOBAL DRUG DISCOVERY AND DEVELOPMENT IVUS CORONARY
RESEARCH APPLICATIONS MARKET BY REGION, THROUGH 2017 ($ MILLIONS) 77
Angioplasty/Stent Evaluation 77
TABLE 40 GLOBAL ANGIOPLASTY/STENT EVALUATION IVUS CORONARY RESEARCH
APPLICATIONS MARKET BY REGION, THROUGH 2017 ($ MILLIONS) 78
Atherosclerosis Process and Others 78
TABLE 41 GLOBAL ATHEROSCLEROSIS AND OTHER IVUS CORONARY
INTERVENTION APPLICATIONS MARKET BY REGION, THROUGH 2017 ($ MILLIONS) 79
IVUS NONCORONARY/PERIPHERAL APPLICATIONS MARKET 80
DRIVERS 80
TABLE 42 GLOBAL IVUS NONCORONARY/PERIPHERAL APPLICATION MARKET BY
TYPE OF APPLICATION, THROUGH 2017 ($ MILLIONS) 81
TABLE 43 GLOBAL IVUS NONCORONARY/PERIPHERAL APPLICATIONS MARKET BY
REGION, THROUGH 2017 ($ MILLIONS) 81
IVUS Peripheral Diagnostics Applications 81
IVUS Peripheral Intervention Applications 82
IVUS Peripheral Research Applications 82
CHAPTER 7 COMPETITIVE DEVELOPMENTS 84
INTRODUCTION 84
FIGURE 8 DEVELOPMENTS IN GLOBAL INTRAVASCULAR ULTRASOUND MARKET,
2010-APRIL 15, 2013 (%) 84
TABLE 44 DEVELOPMENTS-PRODUCT LAUNCHES/INTRODUCTIONS, 2010-APRIL
2013 86
TABLE 45 DEVELOPMENTS - PARTNERSHIP, AGREEMENTS AND COLLABORATIONS,
2010-APRIL 2013 88
TABLE 46 DEVELOPMENTS - GEOGRAPHIC, SALES OR MANUFACTURING
EXPANSION, 2010-APRIL 2013 90
TABLE 47 DEVELOPMENTS - ACQUISITIONS, 2010-APRIL 2013 91
CHAPTER 8 GEOGRAPHICAL ANALYSIS 93
INTRODUCTION 93
JAPAN 93
DRIVERS AND RESTRAINTS 93
FIGURE 9 IVUS MARKET, JAPAN VERSUS GLOBAL, 2010-2017 ($ MILLIONS) 95
TABLE 48 JAPANESE IVUS MARKET BY PRODUCTS, THROUGH 2017 ($ MILLIONS) 96
TABLE 49 JAPANESE IVUS MARKET BY APPLICATIONS, THROUGH 2017 ($ MILLIONS) 96
TABLE 50 JAPANESE IVUS MARKET BY END USERS, THROUGH 2017 ($ MILLIONS) 97
UNITED STATES (U.S.) 97
DRIVERS AND RESTRAINTS 97
FIGURE 10 U.S. IVUS MARKET, U.S. VERSUS GLOBAL, 2010-2017 ($ MILLIONS) 98
TABLE 51 U.S. IVUS MARKET BY PRODUCTS, THROUGH 2017 ($ MILLIONS) 99
TABLE 52 U.S. IVUS MARKET BY APPLICATION, THROUGH 2017 ($ MILLIONS) 100
TABLE 53 U.S. IVUS MARKET BY END USER, THROUGH 2017 ($ MILLIONS) 100
EUROPE 100
DRIVERS AND RESTRAINTS 101
FIGURE 11 IVUS MARKET, EUROPE VERSUS GLOBAL, 2010-2017 ($ MILLIONS) 101
TABLE 54 EUROPEAN IVUS MARKET BY PRODUCT, THROUGH 2017 ($ MILLIONS) 103
TABLE 55 EUROPEAN IVUS MARKET BY APPLICATION, THROUGH 2017 ($ MILLIONS) 103
TABLE 56 EUROPEAN IVUS MARKET BY END USER, THROUGH 2017 ($ MILLIONS) 104
ASIA AND REST OF THE WORLD (ROW) 104
DRIVERS AND RESTRAINTS 104
FIGURE 12 IVUS MARKET, ASIA AND ROW VERSUS GLOBAL, 2010-2017 ($
MILLIONS) 105
TABLE 57 ASIAN AND ROW IVUS MARKET BY PRODUCT, THROUGH 2017 ($
MILLIONS) 106
TABLE 58 ASIAN AND ROW IVUS MARKET BY APPLICATION, THROUGH 2017 ($
MILLIONS) 107
TABLE 59 ASIAN AND ROW IVUS MARKET BY END USER, THROUGH 2017 ($
MILLIONS) 108
CHAPTER 9 PATENTS 110
TABLE 60 LIST OF U.S. PATENTS, 2010-2013 110
TABLE 61 LIST OF EUROPE PATENTS, 2010-2013 114
TABLE 62 LIST OF JAPAN PATENTS, 2010-2011 115
CHAPTER 10 COMPANY PROFILES 117
AVINGER, INC. 117
COMPANY OVERVIEW 117
BUSINESS AND PRODUCTS OVERVIEW 117
BUSINESS STRATEGY 117
BOSTON SCIENTIFIC CORPORATION 118
COMPANY OVERVIEW 118
BUSINESS OVERVIEW 118
PRODUCTS OVERVIEW 118
TABLE 63 BOSTON SCIENTIFIC CORPORATION IVUS AND RELATED PRODUCT
PORTFOLIO 119
FINANCIAL OVERVIEW 119
TABLE 64 BOSTON SCIENTIFIC CORPORATION NET SALES AND RandD EXPENDITURE,
2010-2012 ($ MILLIONS) 120
TABLE 65 BOSTON SCIENTIFIC CORPORATION NET SALES BY REGION, 2010-2012
($ MILLIONS) 120
TABLE 66 BOSTON SCIENTIFIC CORPORATION NET SALES BY BUSINESS SEGMENTS,
2010-2012 ($ MILLIONS) 120
BUSINESS STRATEGY 121
EV3 (COVIDIEN) 121
COMPANY OVERVIEW 121
BUSINESS AND PRODUCTS OVERVIEW 121
BUSINESS STRATEGY 122
GE HEALTHCARE 122
COMPANY AND FINANCIAL OVERVIEW 122
BUSINESS AND PRODUCTS OVERVIEW 122
BUSINESS STRATEGY 123
INFRAREDX, INC. 123
COMPANY OVERVIEW 123
BUSINESS AND PRODUCTS OVERVIEW 123
TABLE 67 INFRAREDX IVUS AND RELATED PRODUCT PORTFOLIO 124
BUSINESS STRATEGY 124
MEDTRONIC 125
COMPANY OVERVIEW 125
BUSINESS AND PRODUCTS OVERVIEW 125
BUSINESS STRATEGY 125
PHILIPS HEALTHCARE 126
COMPANY AND FINANCIAL OVERVIEW 126
BUSINESS AND PRODUCTS OVERVIEW 126
BUSINESS STRATEGY 126
PIE MEDICAL IMAGING BV 127
COMPANY OVERVIEW 127
BUSINESS AND PRODUCTS OVERVIEW 127
BUSINESS STRATEGY 128
SIEMENS HEALTHCARE DIAGNOSTICS, INC. (U.S.) 128
COMPANY AND FINANCIAL OVERVIEW 128
BUSINESS AND PRODUCTS OVERVIEW 128
BUSINESS STRATEGY 129
SILICON VALLEY MEDICAL INSTRUMENTS, INC. (SVMI) 129
COMPANY AND BUSINESS OVERVIEW 129
BUSINESS AND PRODUCTS OVERVIEW 129
BUSINESS STRATEGY 130
ST. JUDE MEDICAL 130
COMPANY OVERVIEW 130
BUSINESS OVERVIEW 131
PRODUCTS OVERVIEW 131
FINANCIAL OVERVIEW 131
BUSINESS STRATEGY 132
TERUMO CORPORATION 132
COMPANY OVERVIEW 132
BUSINESS OVERVIEW 132
PRODUCTS OVERVIEW 133
TABLE 68 TERUMO CORPORATION IVUS AND RELATED PRODUCT PORTFOLIO 133
TABLE 69 TERUMO CORPORATION NET SALES AND RandD EXPENDITURE, 2010-2012
(YEN MILLION) 134
TABLE 70 TERUMO CORPORATION NET SALES BY REGION, 2010-2012 (YEN BILLION) 134
TABLE 71 TERUMO CORPORATION NET SALES BY BUSINESS SEGMENTS, 2010-2012
(YEN BILLION) 134
BUSINESS STRATEGY 134
VOLCANO CORPORATION 135
COMPANY OVERVIEW 135
BUSINESS OVERVIEW 135
PRODUCTS OVERVIEW 135
TABLE 72 VOLCANO CORPORATION IVUS AND RELATED PRODUCT PORTFOLIO 136
FINANCIAL OVERVIEW 136
TABLE 73 VOLCANO CORPORATION REVENUES AND RandD EXPENDITURE,
2010-2012, AS OF DECEMBER 2012 ($ MILLIONS) 137
TABLE 74 VOLCANO CORPORATION REVENUES BY BUSINESS SEGMENTS,
2010-2012 ($ MILLIONS) 137
TABLE 75 VOLCANO CORPORATION REVENUES BY REGION, 2010-2012 ($
MILLIONS) 138
BUSINESS STRATEGY 138

LIST OF TABLES

SUMMARY TABLE GLOBAL IVUS PRODUCTS MARKET BY REGION, THROUGH 2017 ($
MILLIONS) 7
TABLE 1 APPROXIMATE GLOBAL IVUS PENETRATION IN PCI 2012, BY REGION
(THOUSANDS/%) 21
TABLE 2 GLOBAL IVUS MARKET BY PRODUCTS, THROUGH 2017 ($ MILLIONS) 38
TABLE 3 GLOBAL IVUS PRODUCTS MARKET BY REGION, THROUGH 2017 ($ MILLIONS) 39
TABLE 4 GLOBAL IVUS CONSOLES MARKET BY TYPE OF CONSOLE, THROUGH 2017
($ MILLIONS) 40
TABLE 5 GLOBAL IVUS CONSOLES MARKET BY REGION, THROUGH 2017 ($ MILLIONS) 40
TABLE 6 GLOBAL IVUS INTEGRATED CONSOLES MARKET BY REGION, THROUGH
2017 ($ MILLIONS) 42
TABLE 7 GLOBAL CART IVUS CONSOLES MARKET BY REGION, THROUGH 2017 ($
MILLIONS) 43
TABLE 8 GLOBAL IVUS CATHETERS MARKET BY TYPE OF CATHETER, THROUGH 2017
($ MILLIONS) 46
TABLE 9 GLOBAL IVUS CATHETERS MARKET BY REGION, THROUGH 2017 ($
MILLIONS) 46
TABLE 10 GLOBAL IVUS MECHANICAL ROTATORY CATHETERS MARKET BY REGION,
THROUGH 2017 ($ MILLIONS) 47
TABLE 11 GLOBAL IVUS STATIC ELECTRONIC (PHASED ARRAY) CATHETERS MARKET
BY REGION, THROUGH 2017 ($ MILLIONS) 48
TABLE 12 GLOBAL IVUS ACCESSORIES MARKET BY TYPE OF ACCESSORY, THROUGH
2017 ($ MILLIONS) 48
TABLE 13 GLOBAL IVUS ACCESSORIES MARKET BY REGION THROUGH 2017 ($
MILLIONS) 49
TABLE 14 GLOBAL IVUS SOFTWARE MARKET BY REGION, THROUGH 2017 ($
MILLIONS) 52
TABLE 15 GLOBAL IVUS SERVICES MARKET BY REGION, THROUGH 2017 ($ MILLIONS) 53
TABLE 16 GLOBAL IVUS MARKET BY END USERS, THROUGH 2017 ($ MILLIONS) 56
TABLE 17 GLOBAL IVUS END-USER MARKET BY REGION, THROUGH 2017 ($
MILLIONS) 56
TABLE 18 IVUS HOSPITAL END-USER MARKET BY REGION, THROUGH 2017 ($
MILLIONS) 58
TABLE 19 GLOBAL IVUS STAND-ALONE LABS END-USER MARKET BY REGION,
THROUGH 2017 ($ MILLIONS) 58
TABLE 20 IVUS RESEARCH CENTERS AND ORGANIZATIONS END-USER MARKET BY
REGION, THROUGH 2017 ($ MILLIONS) 60
TABLE 21 IVUS COMMERCIAL ORGANIZATIONS END-USER MARKET BY REGION,
THROUGH 2017 ($ MILLIONS) 61
TABLE 22 GLOBAL IVUS APPLICATION MARKET BY TYPES OF APPLICATIONS,
THROUGH 2017 ($ MILLIONS) 63
TABLE 23 GLOBAL IVUS APPLICATIONS MARKET BY REGION, THROUGH 2017 ($
MILLIONS) 63
TABLE 24 GLOBAL IVUS CORONARY APPLICATION MARKET BY TYPE OF APPLICATION,
THROUGH 2017 ($ MILLIONS) 65
TABLE 25 GLOBAL IVUS CORONARY APPLICATIONS MARKET BY REGION, THROUGH
2017 ($ MILLIONS) 65
TABLE 26 GLOBAL IVUS CORONARY DIAGNOSTIC APPLICATIONS MARKET BY TYPE OF
APPLICATION, THROUGH 2017 ($ MILLIONS) 66
TABLE 27 GLOBAL IVUS CORONARY DIAGNOSTIC APPLICATIONS MARKET BY REGION,
THROUGH 2017 ($ MILLIONS) 66
TABLE 28 GLOBAL LESION CHARACTERIZATION/DECISION ON PCI SIZING AND
STRATEGY IVUS CORONARY INTERVENTION APPLICATIONS MARKET BY REGION,
THROUGH 2017 ($ MILLIONS)
67
TABLE 29 GLOBAL ANGIOGRAPHICALLY INTERMEDIATE LESIONS/LESION
SIGNIFICANCE IVUS CORONARY DIAGNOSTIC APPLICATIONS MARKET BY REGION,
THROUGH 2017 ($ MILLIONS)
69
TABLE 30 GLOBAL OTHER IVUS CORONARY DIAGNOSTIC APPLICATIONS MARKET BY
REGION, THROUGH 2017 ($ MILLIONS) 70
TABLE 31 GLOBAL IVUS CORONARY INTERVENTIONS APPLICATIONS MARKET BY
TYPE OF APPLICATION, THROUGH 2017 ($ MILLIONS) 71
TABLE 32 GLOBAL IVUS CORONARY INTERVENTIONS APPLICATIONS MARKET BY
REGION, THROUGH 2017 ($ MILLIONS) 71
TABLE 33 GLOBAL GUIDANCE FOR ANGIOPLASTY IVUS CORONARY INTERVENTION
APPLICATIONS MARKET BY REGION, THROUGH 2017 ($ MILLIONS) 72
TABLE 34 GLOBAL GUIDANCE FOR PLAQUE MODIFICATION IVUS CORONARY
INTERVENTION APPLICATIONS MARKET BY REGION, THROUGH 2017 ($ MILLIONS) 73
TABLE 35 GLOBAL STENT THROMBOSIS AND RESTENOSIS IVUS CORONARY
INTERVENTION APPLICATIONS MARKET BY REGION, THROUGH 2017 ($ MILLIONS) 74
TABLE 36 GLOBAL OTHER IVUS CORONARY INTERVENTION APPLICATIONS MARKET
BY REGION, THROUGH 2017 ($ MILLIONS) 75
TABLE 37 GLOBAL IVUS CORONARY RESEARCH APPLICATIONS MARKET BY TYPE OF
AREA OF RESEARCH, THROUGH 2017 ($ MILLIONS) 76
TABLE 38 GLOBAL IVUS CORONARY RESEARCH APPLICATIONS MARKET BY REGION,
THROUGH 2017 ($ MILLIONS) 76
TABLE 39 GLOBAL DRUG DISCOVERY AND DEVELOPMENT IVUS CORONARY
RESEARCH APPLICATIONS MARKET BY REGION, THROUGH 2017 ($ MILLIONS) 77
TABLE 40 GLOBAL ANGIOPLASTY/STENT EVALUATION IVUS CORONARY RESEARCH
APPLICATIONS MARKET BY REGION, THROUGH 2017 ($ MILLIONS) 78
TABLE 41 GLOBAL ATHEROSCLEROSIS AND OTHER IVUS CORONARY INTERVENTION
APPLICATIONS MARKET BY REGION, THROUGH 2017 ($ MILLIONS) 79
TABLE 42 GLOBAL IVUS NONCORONARY/PERIPHERAL APPLICATION MARKET BY TYPE
OF APPLICATION, THROUGH 2017 ($ MILLIONS) 81
TABLE 43 GLOBAL IVUS NONCORONARY/PERIPHERAL APPLICATIONS MARKET BY
REGION, THROUGH 2017 ($ MILLIONS) 81
TABLE 44 DEVELOPMENTS-PRODUCT LAUNCHES/INTRODUCTIONS, 2010-APRIL 2013 86
TABLE 45 DEVELOPMENTS - PARTNERSHIP, AGREEMENTS AND COLLABORATIONS,
2010-APRIL 2013 88
TABLE 46 DEVELOPMENTS - GEOGRAPHIC, SALES OR MANUFACTURING EXPANSION,
2010-APRIL 2013 90
TABLE 47 DEVELOPMENTS - ACQUISITIONS, 2010-APRIL 2013 91
TABLE 48 JAPANESE IVUS MARKET BY PRODUCTS, THROUGH 2017 ($ MILLIONS) 96
TABLE 49 JAPANESE IVUS MARKET BY APPLICATIONS, THROUGH 2017 ($ MILLIONS) 96
TABLE 50 JAPANESE IVUS MARKET BY END USERS, THROUGH 2017 ($ MILLIONS) 97
TABLE 51 U.S. IVUS MARKET BY PRODUCTS, THROUGH 2017 ($ MILLIONS) 99
TABLE 52 U.S. IVUS MARKET BY APPLICATION, THROUGH 2017 ($ MILLIONS) 100
TABLE 53 U.S. IVUS MARKET BY END USER, THROUGH 2017 ($ MILLIONS) 100
TABLE 54 EUROPEAN IVUS MARKET BY PRODUCT, THROUGH 2017 ($ MILLIONS) 103
TABLE 55 EUROPEAN IVUS MARKET BY APPLICATION, THROUGH 2017 ($ MILLIONS) 103
TABLE 56 EUROPEAN IVUS MARKET BY END USER, THROUGH 2017 ($ MILLIONS) 104
TABLE 57 ASIAN AND ROW IVUS MARKET BY PRODUCT, THROUGH 2017 ($ MILLIONS) 106
TABLE 58 ASIAN AND ROW IVUS MARKET BY APPLICATION, THROUGH 2017 ($
MILLIONS) 107
TABLE 59 ASIAN AND ROW IVUS MARKET BY END USER, THROUGH 2017 ($
MILLIONS) 108
TABLE 60 LIST OF U.S. PATENTS, 2010-2013 110
TABLE 61 LIST OF EUROPE PATENTS, 2010-2013 114
TABLE 62 LIST OF JAPAN PATENTS, 2010-2011 115
TABLE 63 BOSTON SCIENTIFIC CORPORATION IVUS AND RELATED PRODUCT
PORTFOLIO 119
TABLE 64 BOSTON SCIENTIFIC CORPORATION NET SALES AND RandD EXPENDITURE,
2010-2012 ($ MILLIONS) 120
TABLE 65 BOSTON SCIENTIFIC CORPORATION NET SALES BY REGION, 2010-2012 ($
MILLIONS) 120
TABLE 66 BOSTON SCIENTIFIC CORPORATION NET SALES BY BUSINESS SEGMENTS,
2010-2012 ($ MILLIONS) 120
TABLE 67 INFRAREDX IVUS AND RELATED PRODUCT PORTFOLIO 124
TABLE 68 TERUMO CORPORATION IVUS AND RELATED PRODUCT PORTFOLIO 133
TABLE 69 TERUMO CORPORATION NET SALES AND RandD EXPENDITURE, 2010-2012
(YEN MILLION) 134
TABLE 70 TERUMO CORPORATION NET SALES BY REGION, 2010-2012 (YEN BILLION) 134
TABLE 71 TERUMO CORPORATION NET SALES BY BUSINESS SEGMENTS, 2010-2012
(YEN BILLION) 134
TABLE 72 VOLCANO CORPORATION IVUS AND RELATED PRODUCT PORTFOLIO 136
TABLE 73 VOLCANO CORPORATION REVENUES AND RandD EXPENDITURE, 2010-2012,
AS OF DECEMBER 2012 ($ MILLIONS) 137
TABLE 74 VOLCANO CORPORATION REVENUES BY BUSINESS SEGMENTS, 2010-2012
($ MILLIONS) 137
TABLE 75 VOLCANO CORPORATION REVENUES BY REGION, 2010-2012 ($ MILLIONS) 138

LIST OF FIGURES

SUMMARY FIGURE GLOBAL IVUS PRODUCTS MARKET BY REGION, 2010-2017 ($
MILLIONS) 7
FIGURE 1 MARKET SHARE OF KEY PRODUCTS IN IVUS MARKET, 2012 (%) 11
FIGURE 2 KEY APPLICATIONS AREAS OF IVUS VERSUS TOTAL APPLICATION,
2010-2017 ($ MILLIONS) 13
FIGURE 3 MARKET SHARE OF KEY END USERS IN IVUS MARKET, 2012 (%) 14
FIGURE 4 GLOBAL IVUS MARKET SHARE BY KEY MARKET PLAYERS, 2012 (%) 29
FIGURE 5 JAPANESE IVUS MARKET SHARE BY KEY MARKET PLAYERS, 2012 (%) 29
FIGURE 6 U.S. IVUS MARKET SHARE BY KEY MARKET PLAYERS, 2012 (%) 30
FIGURE 7 PATENT ANALYSIS BY REGION, 2010-FEBRUARY 2013 (%) 34
FIGURE 8 DEVELOPMENTS IN GLOBAL INTRAVASCULAR ULTRASOUND MARKET,
2010-APRIL 15, 2013 (%) 84
FIGURE 9 IVUS MARKET, JAPAN VERSUS GLOBAL, 2010-2017 ($ MILLIONS) 95
FIGURE 10 U.S. IVUS MARKET, U.S. VERSUS GLOBAL, 2010-2017 ($ MILLIONS) 98
FIGURE 11 IVUS MARKET, EUROPE VERSUS GLOBAL, 2010-2017 ($ MILLIONS) 101
FIGURE 12 IVUS MARKET, ASIA AND ROW VERSUS GLOBAL, 2010-2017 ($ MILLIONS) 10

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