Global Pharmaceutical Contract Manufacturing Market 

  • August 2013
  • -
  • Frost & Sullivan
  • -
  • 300 pages

Injectable Dose Formulations will Likely Spur the Growth of CMOs

Big pharma companies increasingly consider outsourcing manufacturing to CMOs as a strategic move because of the uncomplicated, timely, and cost-effective services CMOs provide as well as the fact that companes can then focus on their core competencies. This study provides market overview, market engineering measurements, revenue forecasts, competitive analysis, and key trends for the pharmaceutical contract manufacturing market and its segments. Regional analysis includes The United States, European countries such as the United Kingdom, Germany, France, Italy, Spain, Benelux, Scandinavia, and Rest of World are covered. The period covered in the study is from 2009 to 2017, with the base year of 2012.

Methodology

-Primary interviews were conducted with industry stakeholders such as Tier I and Tier II contract manufacturing organisations (CMOs), pharmaceutical and biotech companies, industry experts, and regulatory authorities. Designation of interviewed participants include chief executive officers, marketing managers, directors, and vice presidents.
-Secondary research sources such as in-house Frost & Sullivan database, Frost & Sullivan’s Decision Support Database, company annual reports, scientific journals, and industry-related articles have been utilised.
-For the purpose of this research, pharmaceutical contract manufacturing refers to secondary manufacturing of finished dose formulations for small molecules. Manufacturing of active pharmaceutical ingredients (APIs) and intermediates are excluded.
-Revenues are from contract manufacturing and development services such as formulation, pre-formulation, packaging, testing, validation, regulatory, optimisation, and fill and finish services.
-Over-the-counter (OTC) products have not been included in the scope of this study.

Market Segmentation

The pharmaceutical contract manufacturing market can be broadly divided into 3 main segments: Solid dose formulations, liquid and semi-solid dose formulations, and injectable dose formulations.
-Solid dose formulations comprise basic (tablets and capsules) and advanced (controlled-release), fast-dissolving, and soft-gel, which are multi-active pharmaceutical ingredient (API) oral finished dose formulations.
-Liquid and semi-solid dose formulations include nasal, nebulized, ophthalmic, otic, and topical formulations, including sterile and non-sterile preparations.
-Injectable dose formulations are sterile preparations, including small- and large-volume parenterals. Small-volume parenterals are of 2 types: cytotoxic and non-cytotoxic.

CEO’s Perspective

- Lyophilisation and manufacturing of sterile products such as cytotoxics will likely be areas of growth potential, given the demand for oncology and high-potency drugs.
- The pharmaceutical contract manufacturing market is highly fragmented, and consolidation is required to improve profitability.
- Thirty percent of existing participants could exit the market due to pricing pressure and low profit margins, mainly in the liquid and semi-solid dose formulations segment.
- Capturing projects at the early life-cycle stage of products and a risk-sharing business model can help build long-term strategic relationships.

Key Findings
-In 2012, the global pharmaceutical contract manufacturing market generated $xx billion in revenue. The forecast shows a compound annual growth rate (CAGR) of xx% from 2012 to 2017.
oThe injectable dose formulations segment will likely be the primary growth driver for outsourcing throughout the forecast period.
-In 2012, solid dose formulations was the largest segment, constituting xx% of the total pharmaceutical contract manufacturing market, and is projected to grow at a CAGR of xx% from 2012 to 2017.
oGenerics will likely be a key growth driver for the solid dose formulations segment; however, this segment will likely lose shares to the injectable dose formulations segment because of big pharma’s shift in focus from small molecules to large molecules.
-Injectable dose formulations is the fastest growing segment and is projected to register a robust CAGR ofxx% from 2012 to 2017.
oKey growth drivers include increased pharmaceutical and biotechnological focus on complex disease areas, trends in disease control, growth in emerging markets, the pharmaceutical patent cliff (several blockbuster drugs losing patent protection), and reformulation of existing products.
oThe major growth contributor is expected to be cytotoxics as both cancer research and the development of new cancer therapies are driving growth in this area.
-The liquid and semi-solid dose formulations segment is quite mature and expected to experience a relatively lower CAGR of xx% from 2012 to 2017.
oDecreasing demand for liquid dose formulations is primarily attributed to transportation, storage, and packaging issues associated with these formulations as well as lower returns compared to injectable dose formulations manufacturing.
oThe sterile liquid and semi-solid dose preparations, particularly nasal ophthalmic dose formulations, are expected to experience strong growth; however, these preparations currently constitute a very small segment of the market.
-Because of big pharma’s increased outsourcing, the pharmaceutical contract manufacturing market is expected to show consistent growth. CMOs are striving to provide greater value proposition for clients by engaging in the early life-cycle stage projects and establishing long-term relationships.
oTo improve their value proposition to manufacturers, many CMOs are focusing on pre-clinical development services and can transition from offering clinical services to offering commercial manufacturing to integrate throughout the value chain of clients.
-Industry consolidation is on an increasing curve. The fragmented market nature will likely intensify pricing pressure and drive down CMO revenues.
-Catalent Inc., Patheon Inc., and Aenova (with the acquisition of the Temmler group) are the top xxmarket participants, constituting a combined share ofxx% in the global pharmaceutical contract manufacturing market.

Key Questions This Study Will Answer

- Is the pharmaceutical contract manufacturing market growing, how long will it continue to grow and at what rate?
- What are the fastest growing segments of the pharmaceutical contract manufacturing market?
- What opportunities exist in the pharmaceutical contract manufacturing industry?
- What are the key drivers and restraints affecting the growth of the CMOs?
- What are the key challenges the CMOs will likely face in the near and long-term future?
- In what ways is the pharmaceutical contract manufacturing industry likely to change to meet industry challenges?

Table Of Contents

Executive Summary
Scope and Segmentation
Market Segmentation
Key Questions This Study Will Answer
Market Engineering Measurements
CEO’s Perspective
Key Findings
Key Companies to Watch
Executive Summary—3 Big Predictions
The Last Word—Discussion
Market Overview
Market Segmentation
Segmentation by Manufacturing Process
Segmentation by Patent Exclusivity Status
Global Market Perspective
Defining CMO Trends in the Future
Competitive Playbook
New Market Opportunities
Key Merger, Acquisition and Partnership Assessment
Drivers, Restraints, and Trends—Total Pharmaceutical Contract Manufacturing Market
Market Drivers
Market Restraints
Market Impact of Key Drivers and Restraints
Forecasts and Trends—Total Pharmaceutical Contract Manufacturing Market
Market Engineering Measurements
Forecast Assumptions
Revenue Forecast
Revenue Forecast Discussion
Percent Revenue Forecast by Region
Revenue Forecast by Region
Key Market Trends
Key Technology Trends
Market Impact of Key Trends
Venture Capital Trends in CMO
Segment Lifecycle Analysis
End-User Analysis/Demand Analysis—Total Pharmaceutical Contract Manufacturing Market
End-user Survey Objectives
End-user Survey Methodology
Outsourcing Trend Analysis by Company Type
Number of CMOs Companies Work With and by Company Type
End-user Classification Based on CMO Use
End-user Breakdown by Company Type
Criteria for CMO Selection
Top 5 Factors for CMO Selection
Top 5 Factors for CMO Selection Discussion
Stated Versus Unstated Importance of Selection Factors
Stated Versus Unstated Importance of Selection Factors Discussion
Extent of Outsourcing to CMOs by Service Areas
Analysis of Outsourcing Budget Based on Product Revenue
Outsourcing of Pharmaceutical Manufacturing Demand Forecast
Industry Capacity Utilisation Forecast
Industry Capacity Utilisation Forecast Discussion
Market Share and Competitive Analysis—Total Pharmaceutical Contract Manufacturing Market
Market Share
Market Share Analysis
CMO Breakdown by Finished Dose Segments
Solid Dose Formulations Segment Breakdown
Solid Dose Formulations Segment Key Findings
Market Engineering Measurements
Revenue Forecast
Revenue Forecast Discussion
Liquid and Semi-solid Dose Formulations Segment Breakdown
Liquid and Semi-solid Dose Formulations Segment Key Findings
Market Engineering Measurements
Revenue Forecast
Revenue Forecast Discussion
Injectable Dose Formulations Segment Breakdown
Injectable Dose Formulations Segment Key Findings
Market Engineering Measurements
Revenue Forecast
Revenue Forecast Discussion
United States Breakdown
US Pharmaceutical Contract Manufacturing Market—Market Engineering Measurements
US Pharmaceutical Contract Manufacturing Market Revenue Forecast
US Pharmaceutical Contract Manufacturing Market Revenue Forecast Discussion
Solid Dose Formulations Segment Revenue Forecast
Solid Dose Formulations Segment Revenue Forecast Discussion
Liquid and Semi-solid Dose Formulations Segment Revenue Forecast
Liquid and Semi-solid Dose Formulations Segment Revenue Forecast Discussion
Injectable Dose Formulations Segment Revenue Forecast
Injectable Dose Formulations Segment Revenue Forecast Discussion
Pricing Analysis
Market Analysis
PESTLE Analysis
Europe Breakdown
European Pharmaceutical Contract Manufacturing Market—Market Engineering Measurements
European Pharmaceutical Contract Manufacturing Market Revenue Forecast
European Pharmaceutical Contract Manufacturing Market Revenue Forecast Discussion
Solid Dose Formulations Segment Revenue Forecast
Solid Dose Formulations Segment Revenue Forecast Discussion
Liquid and Semi-solid Dose Formulations Segment Revenue Forecast
Liquid and Semi-solid Dose Formulations Segment Revenue Forecast Discussion
Injectable Dose Formulations Segment Revenue Forecast
Injectable Dose Formulations Segment Revenue Forecast Discussion
Pricing Analysis
Market Analysis
PESTLE Analysis
United Kingdom Breakdown
Solid Dose Formulations Segment Revenue Forecast
Solid Dose Formulations Segment Revenue Forecast Discussion
Liquid and Semi-solid Dose Formulations Segment Revenue Forecast
Liquid and Semi-solid Dose Formulations Segment Revenue Forecast Discussion
Injectable Dose Formulations Segment Revenue Forecast
Injectable Dose Formulations Segment Revenue Forecast Discussion
Germany Breakdown
Solid Dose Formulations Segment Revenue Forecast
Solid Dose Formulations Segment Revenue Forecast Discussion
Liquid and Semi-solid Dose Formulations Segment Revenue Forecast
Liquid and Semi-solid Dose Formulations Segment Revenue Forecast Discussion
Injectable Dose Formulations Segment Revenue Forecast
Injectable Dose Formulations Segment Revenue Forecast Discussion
France Breakdown
Solid Dose Formulations Segment Revenue Forecast
Solid Dose Formulations Segment Revenue Forecast Discussion
Liquid and Semi-solid Dose Formulations Segment Revenue Forecast
Liquid and Semi-solid Dose Formulations Segment Revenue Forecast Discussion
Injectable Dose Formulations Segment Revenue Forecast
Injectable Dose Formulations Segment Revenue Forecast Discussion
Italy Breakdown
Solid Dose Formulations Segment Revenue Forecast
Solid Dose Formulations Segment Revenue Forecast Discussion
Liquid and Semi-solid Dose Formulations Segment Revenue Forecast
Liquid and Semi-solid Dose Formulations Segment Revenue Forecast Discussion
Injectable Dose Formulations Segment Revenue Forecast
Injectable Dose Formulations Segment Revenue Forecast Discussion
Spain Breakdown
Solid Dose Formulations Segment Revenue Forecast
Solid Dose Formulations Segment Revenue Forecast Discussion
Liquid and Semi-solid Dose Formulations Segment Revenue Forecast
Liquid and Semi-solid Dose Formulations Segment Revenue Forecast Discussion
Injectable Dose Formulations Segment Revenue Forecast
Injectable Dose Formulations Segment Revenue Forecast Discussion
Scandinavia Breakdown
Solid Dose Formulations Segment Revenue Forecast
Solid Dose Formulations Segment Revenue Forecast Discussion
Liquid and Semi-solid Dose Formulations Segment Revenue Forecast
Liquid and Semi-solid Dose Formulations Segment Revenue Forecast Discussion
Injectable Dose Formulations Segment Revenue Forecast
Injectable Dose Formulations Segment Revenue Forecast Discussion
Benelux Breakdown
Solid Dose Formulations Segment Revenue Forecast
Solid Dose Formulations Segment Revenue Forecast Discussion
Liquid and Semi-solid Dose Formulations Segment Revenue Forecast
Liquid and Semi-solid Dose Formulations Segment Revenue Forecast Discussion
Injectable Dose Formulations Segment Revenue Forecast
Injectable Dose Formulations Segment Revenue Forecast Discussion
Key Companies to Watch
Key Companies to Watch
Catalent
Patheon
Aenova
Famar
Fareva
Haupt Pharma AG
Recipharm AB
DPT Laboratories
Aesica
Baxter BioPharma Solutions
Vetter Pharma
Hospira One 2 One
NextPharma Technologies
The Last Word
The Last Word—Three Big Predictions
The Last Word—Discussion
Legal Disclaimer
Appendix
Market Background
Important Market Metrics
Market Landscape and Pricing
Drivers Explained
Restraints Explained
US Patent Expiration Timetable
Europe Patent Expiration Timetable
Decision Support Database—Total Healthcare Expenditure
Decision Support Database—Public Healthcare Expenditure
Decision Support Database—Private Healthcare Expenditure
Additional Sources of Information on Contract Outsourcing Services
List of Other Key Companies Included in this Research Service
Market Engineering Methodology
Learn More—Next Steps

List of Figures

Total Pharmaceutical Contract Manufacturing Market: Market Segmentation, Global, 2012
Total Pharmaceutical Contract Manufacturing Market: Market Engineering Measurements, Global, 2012
Total Pharmaceutical Contract Manufacturing Market: Percent Sales Breakdown by Segments, Global, 2012
Total Pharmaceutical Contract Manufacturing Market: Percent Sales Breakdown by Manufacturing Process, Global, 2012
Total Pharmaceutical Contract Manufacturing Market: Percent Sales Breakdown by Patent Exclusivity Status, Global, 2012
Total Pharmaceutical Contract Manufacturing Market: Percent Revenue Breakdown by Geographic Region, Global, 2012
Total Pharmaceutical Contract Manufacturing Market: Market Outlook, Global, 2012 and 2022
Total Pharmaceutical Contract Manufacturing Market: Game-changing Strategies, Global, 2012
Total Pharmaceutical Contract Manufacturing Market: Market Outlook, Global, 2010-2012
Total Pharmaceutical Contract Manufacturing Market: Key Market Drivers, Global, 2013-2017
Total Pharmaceutical Contract Manufacturing Market: Key Market Restraints, Global, 2013-2017
Total Pharmaceutical Contract Manufacturing Market: Impact of Key Drivers and Restraints, Global, 2012
Total Pharmaceutical Contract Manufacturing Market: Market Engineering Measurements, Global, 2012
Total Pharmaceutical Contract Manufacturing Market: Revenue Forecast, Global, 2009-2017
Total Pharmaceutical Contract Manufacturing Market: Percent Points Comparison with the US, Global, 2012
Total Pharmaceutical Contract Manufacturing Market: Percent Points Manufacturing Cost Comparison with the US, Global, 2012
Total Pharmaceutical Contract Manufacturing Market: Percent Points Labour Cost Comparison with the US, Global, 2012
Total Pharmaceutical Contract Manufacturing Market: Percent Revenue Forecast by Region, Global, 2009-2017
Total Pharmaceutical Contract Manufacturing Market: Revenue Forecast by Region, Global, 2009-2017
Total Pharmaceutical Market: Combined Prescription Sales for the Top 50 Pharmaceutical Companies by Molecule Type, Global, 2012-2017
Total Pharmaceutical Market: Combined Prescription Sales for the Top 50 Pharmaceutical Companies by Therapeutic Area, Global, 2012-2017
Pharmaceutical Contract Manufacturing Market: Percent of Combined Prescription Sales for Big Pharmaceutical Companies by Molecule Type, Global, 2012-2017
Pharmaceutical Contract Manufacturing Market: Percent of Combined Prescription Sales for Mid-sized Pharmaceutical Companies by Molecule Type, Global,
2012-2017
Total Pharmaceutical Contract Manufacturing Market: Percent Breakdown of Activities Outsourced, Global, 2012
Total Pharmaceutical Contract Manufacturing Market: CAGRs of Segments Likely to Have Higher Levels of Outsourcing, Global, 2012-2019
Total Pharmaceutical Contract Manufacturing Market: Market Impact of Key Trends, Global, 2012
Total Pharmaceutical Contract Manufacturing Market: Segment Lifecycle Analysis, Global, 2012
Total Pharmaceutical Contract Manufacturing Market: Percent Finished Dose Manufacturing Outsourced by Company Type, Global, 2012
Total Pharmaceutical Contract Manufacturing Market: Percent Breakdown of Number of CMOs Companies Work With, Global, 2012
Total Pharmaceutical Contract Manufacturing Market: Percent Breakdown of Number of CMOs Companies Work With by Company Type, Global, 2012
Total Pharmaceutical Contract Manufacturing Market: End-user Percent Breakdown by CMO Budget, Global, 2012
Total Pharmaceutical Contract Manufacturing Market: End-user Percent Breakdown by Company Type, Global, 2012
Total Pharmaceutical Contract Manufacturing Market: Customer Utility Value of Various Factors Involved in the Selection of a CMO, Global, 2012
Total Pharmaceutical Contract Manufacturing Market: Percent Breakdown of Top 5 Factors for CMO Selection, Global, 2012
Total Pharmaceutical Contract Manufacturing Market: Percent Breakdown of Top 5 Factors for CMO Selection by Company Type, Global, 2012
Total Pharmaceutical Contract Manufacturing Market: Extent of Outsourcing to CMOs by Service Areas, Global, 2012
Total Pharmaceutical Contract Manufacturing Market: Extent of Outsourcing to CMOs by Service Areas, Global, 2017
Total Pharmaceutical Contract Manufacturing Market: Percent Outsourcing Budget Allocation Based on Product Revenue, Global, 2012
Total Pharmaceutical Contract Manufacturing Market: Outsourcing of Pharmaceutical Manufacturing Demand Forecast, Global, 2012-2017
Total Pharmaceutical Contract Manufacturing Market: Industry Capacity Utilization Forecast, Global, 2012-2017
Total Pharmaceutical Contract Manufacturing Market: CMO Market Share, Global, 2012
Total Pharmaceutical Contract Manufacturing Market: CMO Market Share Analysis, Global, 2012
Total Pharmaceutical Contract Manufacturing Market: CMO Breakdown by Finished Dose Segments, Global, 2012
Solid Dose Formulations Segment: Percent Sales Breakdown by Sub-segments, Global, 2012
Solid Dose Formulations Segment: Market Engineering Measurements, Global, 2012
Solid Dose Formulations Segment: Revenue Forecast, Global, 2009-2017
Liquid and Semi-solid Dose Formulations Segment: Percent Sales Breakdown by Sub-segments, Global, 2012
Liquid and Semi-solid Dose Formulations Segment: Market Engineering Measurements, Global, 2012
Liquid and Semi-solid Dose Formulations Segment: Revenue Forecast, Global, 2009-2017
Injectable Dose Formulations Segment: Percent Sales Breakdown by Sub-segments, Global, 2012
Injectable Dose Formulations Segment: Market Engineering Measurements, Global, 2012
Injectable Dose Formulations Segment: Revenue Forecast, Global, 2009-2017
Pharmaceutical Contract Manufacturing Market: Market Engineering Measurements, US, 2012
Pharmaceutical Contract Manufacturing Market: Revenue Forecast, US, 2009-2017
Solid Dose Formulations Segment: Revenue Forecast, US, 2009-2017
Liquid and Semi-solid Dose Formulations Segment: Revenue Forecast, US,
2009-2017
Injectable Dose Formulations Segment: Revenue Forecast, US, 2009-2017
Pharmaceutical Contract Manufacturing Market: Pricing Analysis, US, 2012
Pharmaceutical Contract Manufacturing Market: PESTLE Analysis, US, 2012
Pharmaceutical Contract Manufacturing Market: Market Engineering Measurements, Europe, 2012
Pharmaceutical Contract Manufacturing Market: Revenue Forecast, Europe,
2009-2017
Solid Dose Formulations Segment: Revenue Forecast, Europe, 2009-2017
Liquid and Semi-solid Dose Formulations Segment: Revenue Forecast, Europe, 2009-2017
Injectable Dose Formulations Segment: Revenue Forecast, Europe, 2009-2017
Pharmaceutical Contract Manufacturing Market: Pricing Analysis, Europe, 2012
Pharmaceutical Contract Manufacturing Market: PESTLE Analysis, Europe, 2012
Solid Dose Formulations Segment: Revenue Forecast, United Kingdom, 2009-2017
Liquid and Semi-solid Dose Formulations Segment: Revenue Forecast,
United Kingdom, 2009-2017
Injectable Dose Formulations Segment: Revenue Forecast, United Kingdom,
2009-2017
Solid Dose Formulations Segment: Revenue Forecast, Germany, 2009-2017
Liquid and Semi-solid Dose Formulations Segment: Revenue Forecast, Germany, 2009-2017
Injectable Dose Formulations Segment: Revenue Forecast, Germany, 2009-2017
Solid Dose Formulations Segment: Revenue Forecast, France, 2009-2017
Liquid and Semi-solid Dose Formulations Segment: Revenue Forecast, France, 2009-2017
Injectable Dose Formulations Segment: Revenue Forecast, France, 2009-2017
Solid Dose Formulations Segment: Revenue Forecast, Italy, 2009-2017
Liquid and Semi-solid Dose Formulations Segment: Revenue Forecast, Italy,
2009-2017
Injectable Dose Formulations Segment: Revenue Forecast, Italy, 2009-2017
Solid Dose Formulations Segment: Revenue Forecast, Spain, 2009-2017
Liquid and Semi-solid Dose Formulations Segment: Revenue Forecast, Spain,
2009-2017
Injectable Dose Formulations Segment: Revenue Forecast, Spain, 2009-2017
Solid Dose Formulations Segment: Revenue Forecast, Scandinavia, 2009-2017
Liquid and Semi-solid Dose Formulations Segment: Revenue Forecast, Scandinavia, 2009-2017
Injectable Dose Formulations Segment: Revenue Forecast, Scandinavia, 2009-2017
Solid Dose Formulations Segment: Revenue Forecast, Benelux, 2009-2017
Liquid and Semi-solid Dose Formulations Segment: Revenue Forecast, Benelux, 2009-2017
Injectable Dose Formulations Segment: Revenue Forecast, Benelux, 2009-2017
Total Pharmaceutical Contract Manufacturing Market: Important Market Growth Metrics, Global, 2012
Total Pharmaceutical Contract Manufacturing Market: Client-wise Revenue Contribution to CMOs, Global, 2012
Total Pharmaceutical Contract Manufacturing Market: VC Investment in Pharmaceutical/Biotech Companies and CMOs, Global, 2000-2011
Total Pharmaceutical Contract Manufacturing Market: Key Blockbuster Drugs Losing Patent Protection, US, 2012-2017
Total Pharmaceutical Contract Manufacturing Market: Key Blockbuster Drugs Losing Patent Protection, Europe, 2010-2017
Decision Support Database: Total Healthcare Expenditure, Global, 2008-2018
Decision Support Database: Public Healthcare Expenditure, Global, 2008-2018
Decision Support Database: Private Healthcare Expenditure, Global, 2008-2018

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