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Macrocycles: Discovery and Development, Company Profiles, and Technologies

  • September 2013
  • Insight Pharma Reports
Report ID: 1608259

Summary

Table of Contents

New to Insight Pharma Reports is a report on Macrocycles: Discovery and Development, Company Profiles, and Technologies.

This report covers several areas of macrocycles, specifically in technology and current research in development. With background the first four chapters including background material, this report covers what macrocycles are and the pharmacokinetic properties (absorption, distribution, metabolism, and excretion) they experience. Challenges with these molecules (including plasma concentrations, drug-drug interactions, and drug dose administrations) are also covered. Chapter 3 expands upon other properties that are considered with drug development, specifically cell permeability oral bioavailability, and drug absorption design. Chapter 4 ties all the ends with why macrocycles are being studied and what makes them stand out compared to other drug classes. Additionally, Chapter 4 also includes a survey conducted by Insight Pharma Reports. WIth over 90 participants, questions included familiarity with macrocycles, use in research, and challenges encountered.

Chapters 5-13 detail various companies and their strategies for studying macrocycles as drug candidates. Starting out with background material, Insight Pharma Reports has received the participation of:
• Bicycle Therapeutics
• Encycle Therapeutics
• Ensemble Therapeutics
• Lanthio Pharma
• Oncodesign
• Pepscan
• PeptiDream
• RA Pharmaceuticals
• Tranzyme Pharmaceuticals

Included with each section are detailed descriptions of company overviews, technology platforms, benefits, challenges, competitive advantage, partnerships and future aspirations. Also provided are exclusive interviews at the end of each section.

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