European Markets for Dental Dental Growth Factors 2009

European Markets for Dental Dental Growth Factors 2009

The European markets for dental growth factors include the markets for emdogain, in addition to the markets for potential dental growth factors such as GEM-21S and INFUSE and Platelet Rich Plasma (PRP)

TABLE OF CONTENTS

EUROPEAN MARKETS FOR DENTAL GROWTH FACTORS 2009...........................I

IDATA_EUGF09_RPT ...............................................I

TABLE OF CONTENTS .......................................... II

LIST OF FIGURES ....................................................V

LIST OF CHARTS ...................................................VI

RESEARCH METHODOLOGY .............................. 8

1.1 RESEARCH SCOPE .............................................. 8
1.2 IDATA’S 9-STEP METHODOLOGY ...................... 8
Step 1: Project Initiation & Team Selection ...... 9
Step 2: Prepare Data Systems and Perform Secondary Research.............................. 10
Step 3: Preparation for Interviews & Questionnaire Design ..................................... 11
Step 4: Performing Primary Research ............. 12
Step 5: Research Analysis: Establishing Baseline Estimates ..................................... 14
Step 6: Market Forecast and Analysis ............. 14
Step 7: Identify Strategic Opportunities .......... 16
Step 8: Final Review and Market Release ....... 17
Step 9: Customer Feedback and Market Monitoring.................................................. 18

EUROPEAN DENTAL BONE GRAFT SUBSTITUTES AND OTHER
BIOMATERIALS MARKET .................................. 19

2.1 APPLICATIONS OF DENTAL BONE GRAFT SUBSTITUTES ............................................ 19
2.1.1 Dental Implant Procedures ........................ 20
2.1.2 Periodontal Procedures ............................. 20
2.2 TYPES OF DENTAL BONE GRAFT SUBSTITUTES.......................................................... 21
2.2.1 Autografts ................................................... 21
2.2.2 Allografts ................................................... 21
2.2.3 De-Mineralized Bone Matrix (DBM) Allografts................................................... 22
2.2.4 Xenografts .................................................. 23
2.2.5 Synthetics ................................................... 23
2.3 TISSUE ENGINEERING PRODUCTS .................... 24
2.4 DENTAL MEMBRANES ..................................... 25
2.5MARKET PENETRATION AND END USERS ........ 26
2.6 CURRENCY EXCHANGE RATES ........................ 26

COUNTRY PROFILES ........................................... 29

3.1 INTRODUCTION ................................................ 29
3.1.1 Population .................................................. 29
3.1.2 GDP per Capita ......................................... 31
3.1.3 Bone Graft Volume Used (cc) Per 10,000 Inhabitants ......................................... 33
3.1.4 Price Index ................................................. 35
3.2 GERMANY ........................................................ 37
3.3 FRANCE . 38
3.4 U.K. ...... 39
3.5 ITALY .... 40
3.6 SPAIN .... 41
3.7 BENELUX ......................................................... 42
3.8 SCANDINAVIA .................................................. 43
3.9 SWITZERLAND .................................................. 44
3.10 PORTUGAL ..................................................... 45
3.11 AUSTRIA ........................................................ 46
3.12 POLAND ......................................................... 47
3.13 ISRAEL 48
3.14 EUROPEAN TOOTH LOSS STATISTICS ............ 49
3.15 POPULATION PER DENTIST BY COUNTRY ...... 51

EUROPEAN MARKET FOR EMDOGAIN .......... 54

4.1 INTRODUCTION ................................................ 54
4.2 DENTAL MARKET ANALYSIS AND FORECAST . 55
4.2.1 Total Market for Emdogain by Country ..... 56

POTENTIAL MARKET FOR DENTAL GROWTH FACTORS.................................. 59

5.1 INTRODUCTION ................................................ 59
5.1.1 GEM-21S ................................................... 60
5.1.2 INFUSE ...................................................... 60
5.1.3 Platelet Rich Plasma (PRP) ....................... 60
5.2 DENTAL MARKET ANALYSIS AND FORECAST . 62
5.2.1 Market for GEM-21S ................................. 65
5.2.2 Market for INFUSE ................................... 66
5.3MARKET COMPETITORS ................................... 68

ABBREVIATIONS ................................................... 69

LIST OF FIGURES

RESEARCH METHODOLOGY ................. 8
EUROPEAN DENTAL BONE GRAFT SUBSTITUTES AND OTHER
BIOMATERIALS MARKET ............... 19
Figure 2-1: Exchange Rates for the Euro (€), 2008.............................................. 27
Figure 2-2: Exchange Rates Between European Currencies, 2008 ....................... 28
COUNTRY PROFILES ........................... 29
Figure 3-1: European Country Populations, 2008 ............................................... 29
Figure 3-2: European GDP per Capita, 2008 (US$) ............................................ 31
Figure 3-3: Dental BGS Used (cc) Per 10,000 Inhabitants, Europe, 2008 ............ 33
Figure 3-4: Price Indices for Dental Bone Graft Substitutes, 2008 ...................... 35
Figure 3-5: Population per Dentist by Country, 2008........................................... 52
Figure 3-6: Legend for Chart 3-18: Population per Dentist by Country .............. 52
EUROPEAN MARKET FOR EMDOGAIN ......................................................... 54
Figure 4-1: Total Market for Emdogain, Europe, 2005 – 2015 (€)........................ 55
Figure 4-2: Total Market for Emdogain, Europe, 2005 – 2015 (US$) ................... 56
Figure 4-3: Total Market for Emdogain by Country, Europe, 2005 – 2015 (€) ...... 57
POTENTIAL MARKET FOR DENTAL GROWTH FACTORS............................ 59
Figure 5-1: Total Market for Dental Applications of Growth Factors, Europe,
2010 – 2015 (€) .................................. 63
Figure 5-2: Total Market for Dental Applications of Growth Factors, Europe,
2010 – 2015 (US$) .............................. 63
Figure 5-3: Total European Potential Market for GEM-21S, Europe, 2010 – 2015
(€) ...................................................... 65
Figure 5-4: Total European Potential Market for INFUSE, Europe, 2010 – 2015
(€) ...................................................... 67
ABBREVIATIONS ................................. 69

LIST OF CHART S

RESEARCH METHODOLOGY ................. 8
EUROPEAN DENTAL BONE GRAFT SUBSTITUTES AND OTHER
BIOMATERIALS MARKET ............... 19
COUNTRY PROFILES ........................... 29
Chart 3-1: European Country Populations, 2008................................................. 30
Chart 3-2: European GDP per Capita, 2008 (US$).............................................. 32
Chart 3-3: Dental BGS Used (cc) Per 10,000 Inhabitants, Europe, 2008.............. 34
Chart 3-4: Price Indices for Dental Bone Graft Substitutes, 2008 ....................... 36
Chart 3-5: German Price Index, BGS Used per Capita, GDP per Capita, and
Population, 2008 (US$) ....................... 37
Chart 3-6: French Price Index, BGS Used per Capita, GDP per Capita, and
Population, 2008 (US$) ....................... 38
Chart 3-7: U.K. Price Index, BGS Used per Capita, GDP per Capita, and
Population, 2008 (US$) ....................... 39
Chart 3-8: Italian Price Index, BGS Used per Capita, GDP per Capita, and
Population, 2008 (US$) ....................... 40
Chart 3-9: Spanish Price Index, BGS Used per Capita, GDP per Capita, and
Population, 2008 (US$) ....................... 41
Chart 3-10: Beneluxian Price Index, BGS Used per Capita, GDP per Capita, and
Population, 2008 (US$) ....................... 42
Chart 3-11: Scandinavian Price Index, BGS Used per Capita, GDP per Capita,
and Population, 2008 (US$) ................ 43
Chart 3-12: Swiss Price Index, BGS Used per Capita, GDP per Capita, and
Population, 2008 (US$) ....................... 44
Chart 3-13: Portuguese Price Index, BGS Used per Capita, GDP per Capita, and
Population, 2008 (US$) ....................... 45
Chart 3-14: Austrian Price Index, BGS Used per Capita, GDP per Capita, and
Population, 2008 (US$) ....................... 46