World Apheresis Equipment Industry

  • February 2015
  • -
  • Global Industry Analysts
  • -
  • 214 pages

This report analyzes the worldwide markets for Apheresis Equipment in US$ Thousands by the following Types: Equipment for Therapeutic Apheresis, and Equipment for Donor Apheresis. Global market is analyzed by the following Applications: Erythrocytapheresis, Plasmapheresis, Plateletpheresis, and Others. The report provides separate comprehensive analytics for the US, Canada, Japan, Europe, Asia-Pacific, and Rest of World. Annual estimates and forecasts are provided for the period 2014 through 2020. Also, a seven-year historic analysis is provided for these markets. Market data and analytics are derived from primary and secondary research. Company profiles are primarily based on public domain information including company URLs. The report profiles 14 companies including many key and niche players such as -

Asahi Kasei Medical Co., Ltd.
B Braun Melsungen AG
Cerus Corporation
Fresenius Kabi
Haemonetics Corporation

Table Of Contents

World Apheresis Equipment Industry



I. INTRODUCTION, METHODOLOGY and PRODUCT DEFINITIONS

Study Reliability and Reporting Limitations I-1
Disclaimers I-2
Data Interpretation and Reporting Level I-2
Quantitative Techniques and Analytics I-3
Product Definitions and Scope of Study I-3


II. EXECUTIVE SUMMARY

1. INDUSTRY OVERVIEW II-1
Prelude II-1
Donor Apheresis: Dominating Equipment Sales II-3
Table 1: Active Donors of Whole Blood and Apheresis per 1,000
Population by Country/Agency (2012) (includes corresponding
Graph/Chart) II-3

Table 2: Percentage Breakdown of Apheresis and Whole Blood
Donations by Country (2012) (includes corresponding
Graph/Chart) II-4
Therapeutic Apheresis to Witness Strong Growth II-4
Developed Markets Lead, Developing Nations to Lead the Charge
in Future II-5
Rising Demand for Plasma from Biopharmaceutical Companies -
Opportunity to Tap II-5
Sustained Growth in Blood Collections Favors Apheresis
Equipment Market II-6
Table 3: Total Blood Collections (2014): Percentage Share
Breakdown of Collections (Units) by Segment - Whole Blood and
Apheresis (includes corresponding Graph/Chart) II-7

Table 4: Total Blood Collections (2014): Percentage Share
Breakdown of Collections (Units) for Leukoreduced and
Non-Leukoreduced Blood (includes corresponding Graph/Chart) II-7
Competitive Landscape II-7
Table 5: Leading Players in the Global Apheresis Systems
Market (2013): Percentage Breakdown of Value Sales for
Fresenius/Fenwal, Haemonetics, Terumo BCT, and Others
(includes corresponding Graph/Chart) II-8

Table 6: Leading Players in the Global Blood Component
Collection Market (2013E): Percentage Breakdown of Value
Sales for Fresenius/Fenwal, Haemonetics, Terumo Corp and
Others (includes corresponding Graph/Chart) II-8
Terumo Banks on Growing Apheresis Market II-8
Consolidation of Blood Collectors and Healthcare Providers Puts
Pricing Pressure on Suppliers II-9

2. KEY MARKET TRENDS and DRIVERS II-10
Rising Cancer Incidence to Drive Volume of Apheresis Procedures II-10
Table 7: Worldwide Incidence of Cancer (2013, 2020 and 2030):
Number of New Cases Diagnosed (includes corresponding
Graph/Chart) II-10

Table 8: World Cancer Incidence (2012): Number of New Cancer
Cases Reported (in Thousands) by Geographic Region and Gender
(includes corresponding Graph/Chart) II-11

Table 9: World Cancer Mortality (2012): Number of
Cancer-Related Deaths (in Thousands) by Geographic Region and
Gender (includes corresponding Graph/Chart) II-12

Table 10: New Cancer Cases in the World by Affected Site
(2012) (In Thousands) (includes corresponding Graph/Chart) II-13
Technological Advancements and Novel Indications Augur Well
for Apheresis Market II-13
Blood Supply Shortage and Safety Concerns Bode Well for
Apheresis Market II-14
Photopheresis: A Popular Therapeutic Apheresis Procedure II-14
Plasmapheresis Continues to Lead the Apheresis Market II-15
Table 11: Plasma Collection Methods: Percentage Share
Breakdown by Fractionation and Extraction from Whole Blood
(2013 Vs. 2010) (includes corresponding Graph/Chart) II-15
Plateletpheresis Emerges as the ‘Treatment of Choice' II-16
Increase in Number of Platelet Donors Drives Apheresis Procedures II-16
Pediatrics: An Unexplored Domain in Therapeutic Apheresis II-16
Automated Blood Processing Systems in Open Heart Surgeries II-17
CFA - An Effective Way to Pull Up Cold Hemagglutinin Disease II-17
Improving Healthcare Expenditure to Drive Demand II-17
Table 12: Per-Capita Healthcare Expenditure in Select Regions
(2013) (includes corresponding Graph/Chart) II-18

Table 13: Healthcare Spending as a Percentage of GDP (2012)
(includes corresponding Graph/Chart) II-19
Aging Population: A Strong Growth Driver II-19
Table 14: Global Population Statistics for the 65+ Age Group
(2013) (includes corresponding Graph/Chart) II-20

Table 15: Elderly Population (60+ Years) as a Percentage of
the Total Population (2012 and 2050) (includes corresponding
Graph/Chart) II-21

Table 16: Life Expectancy at Age 60 and 80 Years -
(2010-2015), (2020-2025) and (2045-2050) (includes
corresponding Graph/Chart) II-21
Key Challenges and Issues II-22
Lack of Awareness among Patients Restrains Market Growth II-22
Vendors' Attitude Hampers Growth Prospects of Therapeutic
Apheresis II-22
Development of Inexpensive Apheresis Therapies II-22
Scarcity of Qualified Donors II-22
Challenges for Therapeutic Apheresis in the Unexplored
Pediatrics Segment II-23

3. TECHNOLOGY OVERVIEW II-24
Apheresis - The Definition II-24
Apheresis Vs Whole Blood Collection II-24
Comparison of Apheresis and Whole Blood Collection II-25
The Process of Apheresis - An Overview II-25
Blood Components II-25
Apheresis Procedure II-26
Duration, Frequency, and Efficiency of Apheresis II-26
Segregation of Blood Components II-26
Centrifugation II-26
Centrifugal Cell Separators II-27
Filtration II-27
Side Effects II-27
Types of Apheresis Procedures II-27
Plasmapheresis II-27
Plasma Exchange and Plasmapheresis: The Difference II-28
Therapeutic Plasma Exchange (TPE) or Plasma Exchange II-28
TPE: Abnormal Components Removed from Blood II-28
Plasmapheresis: Potential Uses Discovered in the Early Years II-29
Potential Use of Plasmapheresis in Select Diseases
Discovered in the Early Years II-29
Erythrocytapheresis II-29
Plateletpheresis II-29
Leukapheresis II-30
Photopheresis II-30
Functioning of THERAKOSâ„¢ - A Typical Photopheresis System II-30
Lipidpheresis II-30
Cytapheresis II-31
Stem Cell Collection II-31
Apheresis - A Review of Segmentation II-31
Donor Apheresis II-31
Process of Donor Apheresis II-31
Automated Blood Donation Procedures II-32
Safety of the Donor II-32
Blood Components Required by Different Patients II-33
Automated Apheresis II-33
Therapeutic Apheresis: An Introduction II-34
Therapeutic Apheresis Techniques II-34
Applications of Therapeutic Apheresis II-35
Categories of Indications for Therapeutic Apheresis II-37
Therapeutic Apheresis is Remedial for Various Diseases II-38
Indications for Therapeutic Apheresis II-38
Type of Therapeutic Apheresis Procedure Used in Different
Medication Conditions II-39
Emerging Applications of Therapeutic Apheresis II-39
Cost of Select Therapeutic Apheresis Procedures: An Overview II-40
1. Photopheresis in GVHD (Graft-Versus-Host Disease) II-40
2. Lipid Apheresis (LDL Apheresis) II-40
3. Plasmapheresis and Other Procedures II-40
Therapeutic Apheresis: What is the Risk Involved? II-40
Replacement Fluid in Therapeutic Apheresis II-41
Replacement Fluids Used in Therapeutic Apheresis II-41
Various Replacement Fluids in Use II-42
Select Replacement Fluids and their Limitations II-42
Table 17: Fluid Balance in Fluid Replacement II-42
Table 18: Volume Exchange of Plasma Constituents (includes
corresponding Graph/Chart) II-42
Table 19: Removal of IgM and IgG by Plasma Exchange Volume
(includes corresponding Graph/Chart) II-43
Table 20: Therapeutic Apheresis: Percentage Decrease and
Restoration of Blood Components II-43
Complications Involved and Suggested Treatment in the
Therapeutic Apheresis Procedure II-44
Therapeutic Plasmapheresis with Fresh Frozen Plasma (FFP)
Replacement II-45

4. BLOOD COMPONENTS and DERIVATIVES II-46
Red Blood Cells (RBCs) II-46
White Blood Cells (WBCs) II-46
Platelets II-46
Sources of Blood Plasma II-47
Facts About Plasma and its Donation II-47
Pre-requisites for Plasma Donors II-48
The Complex Process of Becoming a Donor II-48
Medical Screening II-49
The Process of Plasma Donation II-49
Select IQPP-authorized Plasma Collection Centers (US) II-49
Ionic Composition of Blood II-50
Types of Blood II-50
General Facts about Blood II-51
General Uses of Blood II-51
Blood - Global Facts II-51

5. PRODUCT DEVELOPMENTS/APPROVALS II-52
FDA Approves IDE Supplement for Cerus' INTERCEPT Blood System II-52
Health Canada Approves WBCD and PMN Cell Collection Protocols
for Spectra Optia II-52
USFDA Clears PMN Protocol for Terumo's Spectra Optia II-52
Fenwal's Aurora Plasmapheresis System Receives 60601-1 3rd
Edition Certification II-52
Terumo BCT Receives 510(k) FDA Clearance for RBCX On Spectra
Optia II-52
Health Canada Clears BMP Protocol on Terumo's Spectra Optia II-52
Terumo BCT Receives FDA Approval for Enhancement to MNC
Collection Protocol for Spectra Optia System II-53
Fenwal Unveils Auroraâ„¢ Plasmapheresis System II-53
Terumo BCT Introduces MNC Collection Protocol for Spectra
Optia System II-53
Terumo BCT Unveils New Therapeutic Apheresis Capabilities and
Procedures II-53
Terumo BCT Obtains FDA Approval for PF24 and PF24RT24 on
TrimaAccel System II-53
Fenwal Secures US FDA Approval for Therapeutic Plasma Exchange
Protocol on Amicus® Separator II-53

6. RECENT INDUSTRY ACTIVITY II-54
Terumo BCT Files FDA Submission to Improve Blood Supply Safety II-54
Fenwal Autopheresis-C Instruments Donated for Ebola Virus Study II-54
Terumo opens Production Facility in Vietnam II-54
Terumo Collaborates with Kaneka II-54
Terumo to Distribute Therakos Products in Latin America II-54
Terumo Enters Distribution Agreement with Therakos II-54
The Gores Group Acquires Therakos from Ortho-Clinical Diagnostics II-55
Terumo BCT to Acquire Medservice II-55
Fresenius Kabi Acquires Fenwal Holdings II-55
CaridianBCT Collaborates with Terumo Transfusion to Form
Terumo BCT II-55
Cerus to Enter into Partnership with BSI and American Red
Cross to Commercialize INTERCEPT Plasma II-55

7. FOCUS ON SELECT GLOBAL PLAYERS II-56
Asahi Kasei Medical Co., Ltd. (Japan) II-56
B Braun Melsungen AG (Germany) II-56
Cerus Corporation (US) II-56
Fresenius Kabi (Germany) II-57
Fenwal, Inc. (US) II-57
Haemonetics Corporation (US) II-58
HemaCare Corp. (US) II-58
Kaneka Corporation (Japan) II-59
Kawasumi Laboratories, Inc. (Japan) II-60
Medica SpA (Italy) II-60
NIKKISO Europe GmbH (Germany) II-60
Terumo BCT, Inc. (US) II-60
Therakos, Inc. (US) II-61

8. GLOBAL MARKET PERSPECTIVE II-62
Table 21: World Recent Past, Current and Future Analysis for
Apheresis Equipment Market by Geographic Region - US, Canada,
Japan, Europe, Asia-Pacific (excluding Japan), and Rest of
World Markets Independently Analyzed with Annual Sales Figures
in US$ Thousand for Years 2014 through 2020 (includes
corresponding Graph/Chart) II-62

Table 22: World Historic Review for Apheresis Equipment Market
by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific
(excluding Japan), and Rest of World Markets Independently
Analyzed with Annual Sales Figures in US$ Thousand for Years
2007 through 2013 (includes corresponding Graph/Chart) II-63

Table 23: World 14-Year Perspective for Apheresis Equipment
Market by Geographic Region - Percentage Breakdown of Dollar
Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding
Japan), and Rest of World Markets for Years 2007, 2015 and 2020
(includes corresponding Graph/Chart) II-64

Table 24: World Recent Past, Current and Future Analysis for
Equipment for Therapeutic Apheresis by Geographic Region - US,
Canada, Japan, Europe, Asia-Pacific (excluding Japan), and
Rest of World Markets Independently Analyzed with Annual Sales
Figures in US$ Thousand for Years 2014 through 2020 (includes
corresponding Graph/Chart) II-65

Table 25: World Historic Review for Equipment for Therapeutic
Apheresis by Geographic Region - US, Canada, Japan, Europe,
Asia-Pacific (excluding Japan), and Rest of World Markets
Independently Analyzed with Annual Sales Figures in US$
Thousand for Years 2007 through 2013 (includes corresponding
Graph/Chart) II-66

Table 26: World 14-Year Perspective for Equipment for
Therapeutic Apheresis by Geographic Region - Percentage
Breakdown of Dollar Sales for US, Canada, Japan, Europe,
Asia-Pacific (excluding Japan), and Rest of World Markets for
Years 2007, 2015 and 2020 (includes corresponding Graph/Chart) II-67

Table 27: World Recent Past, Current and Future Analysis for
Equipment for Donor Apheresis by Geographic Region - US,
Canada, Japan, Europe, Asia-Pacific (excluding Japan), and
Rest of World Markets Independently Analyzed with Annual Sales
Figures in US$ Thousand for Years 2014 through 2020 (includes
corresponding Graph/Chart) II-68

Table 28: World Historic Review for Equipment for Donor
Apheresis by Geographic Region - US, Canada, Japan, Europe,
Asia-Pacific (excluding Japan), and Rest of World Markets
Independently Analyzed with Annual Sales Figures in US$
Thousand for Years 2007 through 2013 (includes corresponding
Graph/Chart) II-69

Table 29: World 14-Year Perspective for Equipment for Donor
Apheresis by Geographic Region - Percentage Breakdown of
Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific
(excluding Japan), and Rest of World Markets for Years 2007,
2015 and 2020 (includes corresponding Graph/Chart) II-70

Table 30: World Recent Past, Current and Future Analysis for
Apheresis Equipment by Procedure Type - Erythrocytapheresis,
Plasmapheresis, Plateletpheresis, and Others Markets
Independently Analyzed with Annual Sales Figures in US$
Thousand for Years 2014 through 2020 (includes corresponding
Graph/Chart) II-71

Table 31: World Historic Review for Apheresis Equipment by
Procedure Type - Erythrocytapheresis, Plasmapheresis,
Plateletpheresis, and Others Markets Independently Analyzed
with Annual Sales Figures in US$ Thousand for Years 2007
through 2013 (includes corresponding Graph/Chart) II-72

Table 32: World 14-Year Perspective for Apheresis Equipment by
Procedure Type - Percentage Breakdown of Dollar Sales for
Erythrocytapheresis, Plasmapheresis, Plateletpheresis, and
Others Markets for Years 2007, 2015 and 2020 (includes
corresponding Graph/Chart) II-73


III. MARKET

1. THE UNITED STATES III-1
A.Market Analysis III-1
Current and Future Analysis III-1
Apheresis Market - An Overview III-1
Opportunity Indicator: III-2
Table 33: US Market for Blood Collection by Type (2015E):
Percentage Breakdown of Apheresis and Whole Blood
Collection Procedures for Platelets and RBC (includes
corresponding Graph/Chart) III-2
Blood Donations III-2
Table 34: Blood Transfusions per 1000 population in the US
(2012-2017) (includes corresponding Graph/Chart) III-3
Blood Supply and Demand in the US - A Fact Sheet III-3
Criteria for Platelet Donation III-3
Criteria for Double Red Cell Donation III-4
Plasma Donations III-4
Table 35: Number of Plasma Donations Required Annually by
Disease Type in the US (2012) (includes corresponding
Graph/Chart) III-5
Therapeutic Apheresis Registers Strong Growth III-5
Table 36: US Market for Apheresis Equipment (2015E):
Percentage Share Breakdown of Revenues Generated Through
Procedures by Therapeutic Area (includes corresponding
Graph/Chart) III-5
Competitive Scenario III-6
Table 37: Leading Players in the US Automated Blood
Collection Market (2013E): Percentage Share Breakdown of
Volume Sales for Fresenius, Haemonetics, and Terumo
(includes corresponding Graph/Chart) III-6

Table 38: Leading Players in the US Whole Blood Collection
Market (2013E): Percentage Share Breakdown of Volume Sales
for Fresenius, Haemonetics, Terumo and Others (includes
corresponding Graph/Chart) III-7

Table 39: Leading Players in the US Market for Therapeutic
Apheresis in Neurological Disorders (2013): Percentage
Share Breakdown of Revenues for Fresenius Kabi,
Haemonetics, Terumo BCT, and Others (includes corresponding
Graph/Chart) III-7

Table 40: Leading Players in the US Market for Therapeutic
Apheresis in Neurological Disorders (2013): Percentage
Share Breakdown of Number of Procedures for Fresenius Kabi,
Haemonetics, Terumo BCT, and Others (includes corresponding
Graph/Chart) III-7

Table 41: Leading Players in the US Market for Therapeutic
Apheresis in Hematology and Oncology Disorders (2013):
Percentage Share Breakdown of Revenues for Fresenius Kabi,
Terumo BCT, Therakos, and Others (includes corresponding
Graph/Chart) III-8

Table 42: Leading Players in the US Market for Therapeutic
Apheresis in Hematology and Oncology Disorders (2013):
Percentage Share Breakdown of Number of Procedures for
Fresenius Kabi, Terumo BCT, and Others (includes
corresponding Graph/Chart) III-8
Trima Accel, the Most Widely Used Platelet Collection
Equipment in the US III-8
Consolidation of Blood Collectors and Healthcare Providers
Puts Pricing Pressure on Suppliers III-9
Implications of Healthcare Reforms III-9
An Overview of Regulatory Environment and Reimbursement
Scenario III-10
Reimbursement Policies to Create Growth Opportunities for
Therapeutic Apheresis III-10
Medicaid Coverage for Therapeutic Apheresis by Various
Conditions III-11
Medicaid Coverage for Therapeutic Plasma Exchange III-11
Medicaid covers therapeutic Cytapheresis for the following
conditions: III-12
Medicaid covers Extracorporeal Photopheresis (ECP) for the
following conditions III-12
Table 43: Payment Rates for Apheresis Procedures in 2013 and
2014 (In US$) (includes corresponding Graph/Chart) III-13
Product Launches III-13
Strategic Corporate Developments III-15
Select Players III-16
B.Market Analytics III-20
Table 44: US Recent Past, Current and Future Analysis for
Apheresis Equipment by Segment - Equipment for Therapeutic
Apheresis and Equipment for Donor Apheresis Markets
Independently Analyzed with Annual Sales Figures in US$
Thousand for Years 2014 through 2020 (includes corresponding
Graph/Chart) III-20

Table 45: US Historic Review for Apheresis Equipment by
Segment - Equipment for Therapeutic Apheresis and Equipment
for Donor Apheresis Markets Independently Analyzed with
Annual Sales Figures in US$ Thousand for Years 2007 through
2013 (includes corresponding Graph/Chart) III-21

Table 46: US 14-Year Perspective for Apheresis Equipment by
Segment - Percentage Breakdown of Dollar Sales for Equipment
for Therapeutic Apheresis and Equipment for Donor Apheresis
Markets for Years 2007, 2015 and 2020 (includes corresponding
Graph/Chart) III-22

2. CANADA III-23
A.Market Analysis III-23
Current and Future Analysis III-23
Product Approval III-23
B.Market Analytics III-24
Table 47: Canadian Recent Past, Current and Future Analysis
for Apheresis Equipment by Segment - Equipment for
Therapeutic Apheresis and Equipment for Donor Apheresis
Markets Independently Analyzed with Annual Sales Figures in
US$ Thousand for Years 2014 through 2020 (includes
corresponding Graph/Chart) III-24

Table 48: Canadian Historic Review for Apheresis Equipment
by Segment - Equipment for Therapeutic Apheresis and
Equipment for Donor Apheresis Markets Independently Analyzed
with Annual Sales Figures in US$ Thousand for Years 2007
through 2013 (includes corresponding Graph/Chart) III-25

Table 49: Canadian 14-Year Perspective for Apheresis
Equipment by Segment - Percentage Breakdown of Dollar Sales
for Equipment for Therapeutic Apheresis and Equipment for
Donor Apheresis Markets for Years 2007, 2015 and 2020
(includes corresponding Graph/Chart) III-26

3. JAPAN III-27
A.Market Analysis III-27
Current and Future Analysis III-27
Therapeutic Apheresis Market - An Overview III-27
Growing Demand for Cancer Treatments Drives Plateletpheresis
Market III-27
Key Statistics III-28
Table 50: Leading Companies in the Japanese Whole Blood
Collection Market (2013E): Percentage Share Breakdown of
Volume Sales for Kawasumi and Terumo (includes
corresponding Graph/Chart) III-28

Table 51: Leading Companies in the Japanese Automated Blood
Collection Market (2013E): Percentage Share Breakdown of
Volume Sales for Terumo and Haemonetics (includes
corresponding Graph/Chart) III-28
Select Players III-28
B.Market Analytics III-30
Table 52: Japanese Recent Past, Current and Future Analysis
for Apheresis Equipment by Segment - Equipment for
Therapeutic Apheresis and Equipment for Donor Apheresis
Markets Independently Analyzed with Annual Sales Figures in
US$ Thousand for Years 2014 through 2020 (includes
corresponding Graph/Chart) III-30

Table 53: Japanese Historic Review for Apheresis Equipment
by Segment - Equipment for Therapeutic Apheresis and
Equipment for Donor Apheresis Markets Independently Analyzed
with Annual Sales Figures in US$ Thousand for Years 2007
through 2013 (includes corresponding Graph/Chart) III-31

Table 54: Japanese 14-Year Perspective for Apheresis
Equipment by Segment - Percentage Breakdown of Dollar Sales
for Equipment for Therapeutic Apheresis and Equipment for
Donor Apheresis Markets for Years 2007, 2015 and 2020
(includes corresponding Graph/Chart) III-32

4. EUROPE III-33
A.Market Analysis III-33
Current and Future Analysis III-33
Blood Banking in Europe III-33
Table 55: Leading Players in the European Whole Blood
Collection Market (2013): Percentage Share Breakdown of
Volume Sales for Fresenius, MacoPharma, Terumo and Others
(includes corresponding Graph/Chart) III-34

Table 56: Leading Players in the European Automated Blood
Collection Market (2013E): Percentage Share Breakdown of
Volume Sales for Fresenius, Haemonetics, Terumo and Others
(includes corresponding Graph/Chart) III-34
B.Market Analytics III-35
Table 57: European Recent Past, Current and Future Analysis
for Apheresis Equipment by Geographic Region - France,
Germany, Italy, UK, Spain, and Rest of Europe Markets
Independently Analyzed with Annual Sales Figures in US$
Thousand for Years 2014 through 2020 (includes corresponding
Graph/Chart) III-35

Table 58: European Historic Review for Apheresis Equipment
by Geographic Region - France, Germany, Italy, UK, Spain,
and Rest of Europe Markets Independently Analyzed with
Annual Sales Figures in US$ Thousand for Years 2007 through
2013 (includes corresponding Graph/Chart) III-36

Table 59: European 14-Year Perspective for Apheresis
Equipment by Geographic Region - Percentage Breakdown of
Dollar Sales for France, Germany, Italy, UK, Spain, and Rest
of Europe Markets for Years 2007, 2015 and 2020 (includes
corresponding Graph/Chart) III-37

Table 60: European Recent Past, Current and Future Analysis
for Apheresis Equipment by Segment - Equipment for
Therapeutic Apheresis and Equipment for Donor Apheresis
Markets Independently Analyzed with Annual Sales Figures in
US$ Thousand for Years 2014 through 2020 (includes
corresponding Graph/Chart) III-38

Table 61: European Historic Review for Apheresis Equipment
by Segment - Equipment for Therapeutic Apheresis and
Equipment for Donor Apheresis Markets Independently Analyzed
with Annual Sales Figures in US$ Thousand for Years 2007
through 2013 (includes corresponding Graph/Chart) III-39

Table 62: European 14-Year Perspective for Apheresis
Equipment by Segment - Percentage Breakdown of Dollar Sales
for Equipment for Therapeutic Apheresis and Equipment for
Donor Apheresis Markets for Years 2007, 2015 and 2020
(includes corresponding Graph/Chart) III-40

4a. FRANCE III-41
Market Analysis III-41
Table 63: French Recent Past, Current and Future Analysis for
Apheresis Equipment by Segment - Equipment for Therapeutic
Apheresis and Equipment for Donor Apheresis Markets
Independently Analyzed with Annual Sales Figures in US$
Thousand for Years 2014 through 2020 (includes corresponding
Graph/Chart) III-41

Table 64: French Historic Review for Apheresis Equipment by
Segment - Equipment for Therapeutic Apheresis and Equipment
for Donor Apheresis Markets Independently Analyzed with
Annual Sales Figures in US$ Thousand for Years 2007 through
2013 (includes corresponding Graph/Chart) III-42

Table 65: French 14-Year Perspective for Apheresis Equipment
by Segment - Percentage Breakdown of Dollar Sales for
Equipment for Therapeutic Apheresis and Equipment for Donor
Apheresis Markets for Years 2007, 2015 and 2020 (includes
corresponding Graph/Chart) III-43

4b. GERMANY III-44
A.Market Analysis III-44
Current and Future Analysis III-44
Select Players III-44
B.Market Analytics III-45
Table 66: German Recent Past, Current and Future Analysis for
Apheresis Equipment by Segment - Equipment for Therapeutic
Apheresis and Equipment for Donor Apheresis Markets
Independently Analyzed with Annual Sales Figures in US$
Thousand for Years 2014 through 2020 (includes corresponding
Graph/Chart) III-45

Table 67: German Historic Review for Apheresis Equipment by
Segment - Equipment for Therapeutic Apheresis and Equipment
for Donor Apheresis Markets Independently Analyzed with
Annual Sales Figures in US$ Thousand for Years 2007 through
2013 (includes corresponding Graph/Chart) III-46

Table 68: German 14-Year Perspective for Apheresis Equipment
by Segment - Percentage Breakdown of Dollar Sales for
Equipment for Therapeutic Apheresis and Equipment for Donor
Apheresis Markets for Years 2007, 2015 and 2020 (includes
corresponding Graph/Chart) III-47

4c. ITALY III-48
A.Market Analysis III-48
Current and Future Analysis III-48
Medica Spa - A Select Player III-48
B.Market Analytics III-49
Table 69: Italian Recent Past, Current and Future Analysis for
Apheresis Equipment by Segment - Equipment for Therapeutic
Apheresis and Equipment for Donor Apheresis Markets
Independently Analyzed with Annual Sales Figures in US$
Thousand for Years 2014 through 2020 (includes corresponding
Graph/Chart) III-49

Table 70: Italian Historic Review for Apheresis Equipment by
Segment - Equipment for Therapeutic Apheresis and Equipment
for Donor Apheresis Markets Independently Analyzed with
Annual Sales Figures in US$ Thousand for Years 2007 through
2013 (includes corresponding Graph/Chart) III-50

Table 71: Italian 14-Year Perspective for Apheresis
Equipment by Segment - Percentage Breakdown of Dollar Sales
for Equipment for Therapeutic Apheresis and Equipment for
Donor Apheresis Markets for Years 2007, 2015 and 2020
(includes corresponding Graph/Chart) III-51

4d. THE UNITED KINGDOM III-52
Market Analysis III-52
Table 72: UK Recent Past, Current and Future Analysis for
Apheresis Equipment by Segment - Equipment for Therapeutic
Apheresis and Equipment for Donor Apheresis Markets
Independently Analyzed with Annual Sales Figures in US$
Thousand for Years 2014 through 2020 (includes corresponding
Graph/Chart) III-52

Table 73: UK Historic Review for Apheresis Equipment by
Segment - Equipment for Therapeutic Apheresis and Equipment
for Donor Apheresis Markets Independently Analyzed with
Annual Sales Figures in US$ Thousand for Years 2007 through
2013 (includes corresponding Graph/Chart) III-53

Table 74: UK 14-Year Perspective for Apheresis Equipment by
Segment - Percentage Breakdown of Dollar Sales for Equipment
for Therapeutic Apheresis and Equipment for Donor Apheresis
Markets for Years 2007, 2015 and 2020 (includes corresponding
Graph/Chart) III-54

4e. SPAIN III-55
Market Analysis III-55
Table 75: Spanish Recent Past, Current and Future Analysis for
Apheresis Equipment by Segment - Equipment for Therapeutic
Apheresis and Equipment for Donor Apheresis Markets
Independently Analyzed with Annual Sales Figures in US$
Thousand for Years 2014 through 2020 (includes corresponding
Graph/Chart) III-55

Table 76: Spanish Historic Review for Apheresis Equipment by
Segment - Equipment for Therapeutic Apheresis and Equipment
for Donor Apheresis Markets Independently Analyzed with
Annual Sales Figures in US$ Thousand for Years 2007 through
2013 (includes corresponding Graph/Chart) III-56

Table 77: Spanish 14-Year Perspective for Apheresis
Equipment by Segment - Percentage Breakdown of Dollar Sales
for Equipment for Therapeutic Apheresis and Equipment for
Donor Apheresis Markets for Years 2007, 2015 and 2020
(includes corresponding Graph/Chart) III-57

4f. REST OF EUROPE III-58
Market Analysis III-58
Table 78: Rest of Europe Recent Past, Current and Future
Analysis for Apheresis Equipment by Segment - Equipment for
Therapeutic Apheresis and Equipment for Donor Apheresis
Markets Independently Analyzed with Annual Sales Figures in
US$ Thousand for Years 2014 through 2020 (includes
corresponding Graph/Chart) III-58

Table 79: Rest of Europe Historic Review for Apheresis
Equipment by Segment - Equipment for Therapeutic Apheresis
and Equipment for Donor Apheresis Markets Independently
Analyzed with Annual Sales Figures in US$ Thousand for Years
2007 through 2013 (includes corresponding Graph/Chart) III-59

Table 80: Rest of Europe 14-Year Perspective for Apheresis
Equipment by Segment - Percentage Breakdown of Dollar Sales
for Equipment for Therapeutic Apheresis and Equipment for
Donor Apheresis Markets for Years 2007, 2015 and 2020
(includes corresponding Graph/Chart) III-60

5. ASIA-PACIFIC III-61
Market Analysis III-61
Table 81: Asia-Pacific Recent Past, Current and Future
Analysis for Apheresis Equipment by Geographic Region -
Australia, China and Rest of Asia-Pacific Markets
Independently Analyzed with Annual Sales Figures in US$
Thousand for Years 2014 through 2020 (includes corresponding
Graph/Chart) III-61

Table 82: Asia-Pacific Historic Review for Apheresis
Equipment by Geographic Region - Australia, China and Rest
of Asia-Pacific Markets Independently Analyzed with Annual
Sales Figures in US$ Thousand for Years 2007 through 2013
(includes corresponding Graph/Chart) III-62

Table 83: Asia-Pacific 14-Year Perspective for Apheresis
Equipment by Geographic Region - Percentage Breakdown of
Dollar Sales for Australia, China and Rest of Asia-Pacific
Markets for Years 2007, 2015 and 2020 (includes corresponding
Graph/Chart) III-63

Table 84: Asia-Pacific Recent Past, Current and Future
Analysis for Apheresis Equipment by Segment - Equipment for
Therapeutic Apheresis and Equipment for Donor Apheresis
Markets Independently Analyzed with Annual Sales Figures in
US$ Thousand for Years 2014 through 2020 (includes
corresponding Graph/Chart) III-64

Table 85: Asia-Pacific Historic Review for Apheresis
Equipment by Segment - Equipment for Therapeutic Apheresis
and Equipment for Donor Apheresis Markets Independently
Analyzed with Annual Sales Figures in US$ Thousand for Years
2007 through 2013 (includes corresponding Graph/Chart) III-65

Table 86: Asia-Pacific 14-Year Perspective for Apheresis
Equipment by Segment - Percentage Breakdown of Dollar Sales
for Equipment for Therapeutic Apheresis and Equipment for
Donor Apheresis Markets for Years 2007, 2015 and 2020
(includes corresponding Graph/Chart) III-66

5a. AUSTRALIA III-67
A.Market Analysis III-67
Strategic Corporate Development III-67
B.Market Analytics III-68
Table 87: Australian Recent Past, Current and Future Analysis
for Apheresis Equipment by Segment - Equipment for
Therapeutic Apheresis and Equipment for Donor Apheresis
Markets Independently Analyzed with Annual Sales Figures in
US$ Thousand for Years 2014 through 2020 (includes
corresponding Graph/Chart) III-68

Table 88: Australian Historic Review for Apheresis Equipment
by Segment - Equipment for Therapeutic Apheresis and
Equipment for Donor Apheresis Markets Independently Analyzed
with Annual Sales Figures in US$ Thousand for Years 2007
through 2013 (includes corresponding Graph/Chart) III-69

Table 89: Australian 14-Year Perspective for Apheresis
Equipment by Segment - Percentage Breakdown of Dollar Sales
for Equipment for Therapeutic Apheresis and Equipment for
Donor Apheresis Markets for Years 2007, 2015 and 2020
(includes corresponding Graph/Chart) III-70

5b. CHINA III-71
Market Analysis III-71
Table 90: Chinese Recent Past, Current and Future Analysis for
Apheresis Equipment by Segment - Equipment for Therapeutic
Apheresis and Equipment for Donor Apheresis Markets
Independently Analyzed with Annual Sales Figures in US$
Thousand for Years 2014 through 2020 (includes corresponding
Graph/Chart) III-71

Table 91: Chinese Historic Review for Apheresis Equipment by
Segment -Equipment for Therapeutic Apheresis and Equipment
for Donor Apheresis Markets Independently Analyzed with
Annual Sales Figures in US$ Thousand for Years 2007 through
2013 (includes corresponding Graph/Chart) III-72

Table 92: Chinese 14-Year Perspective for Apheresis
Equipment by Segment - Percentage Breakdown of Dollar Sales
for Equipment for Therapeutic Apheresis and Equipment for
Donor Apheresis Markets for Years 2007, 2015 and 2020
(includes corresponding Graph/Chart) III-73

5c. REST OF ASIA-PACIFIC III-74
A.Market Analysis III-74
Strategic Corporate Development III-74
B.Market Analytics III-75
Table 93: Rest of Asia-Pacific Recent Past, Current and Future
Analysis for Apheresis Equipment by Segment - Equipment for
Therapeutic Apheresis and Equipment for Donor Apheresis
Markets Independently Analyzed with Annual Sales Figures in
US$ Thousand for Years 2014 through 2020 (includes
corresponding Graph/Chart) III-75

Table 94: Rest of Asia-Pacific Historic Review for Apheresis
Equipment by Segment - Equipment for Therapeutic Apheresis
and Equipment for Donor Apheresis Markets Independently
Analyzed with Annual Sales Figures in US$ Thousand for Years
2007 through 2013 (includes corresponding Graph/Chart) III-76

Table 95: Rest of Asia-Pacific 14-Year Perspective for
Apheresis Equipment by Segment - Percentage Breakdown of
Dollar Sales for Equipment for Therapeutic Apheresis and
Equipment for Donor Apheresis Markets for Years 2007, 2015 and
2020 (includes corresponding Graph/Chart) III-77

6. REST OF WORLD III-78
A.Market Analysis III-78
Current and Future Analysis III-78
Strategic Corporate Development III-78
B.Market Analytics III-79
Table 96: Rest of World Recent Past, Current and Future
Analysis for Apheresis Equipment by Segment - Equipment for
Therapeutic Apheresis and Equipment for Donor Apheresis
Markets Independently Analyzed with Annual Sales Figures in
US$ Thousand for Years 2014 through 2020 (includes
corresponding Graph/Chart) III-79

Table 97: Rest of World Historic Review for Apheresis
Equipment by Segment - Equipment for Therapeutic Apheresis
and Equipment for Donor Apheresis Markets Independently
Analyzed with Annual Sales Figures in US$ Thousand for Years
2007 through 2013 (includes corresponding Graph/Chart) III-80

Table 98: Rest of World 14-Year Perspective for Apheresis
Equipment by Segment - Percentage Breakdown of Dollar Sales
for Equipment for Therapeutic Apheresis and Equipment for
Donor Apheresis Markets for Years 2007, 2015 and 2020
(includes corresponding Graph/Chart) III-81


IV. COMPETITIVE LANDSCAPE

Total Companies Profiled: 14 (including Divisions/Subsidiaries - 21)

The United States (9)
Japan (3)
Europe (9)
- Germany (6)
- Italy (3)

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