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World Intracranial Stents Industry

  • January 2015
  • -
  • Global Industry Analysts
  • -
  • 94 pages

This report analyzes the worldwide markets for Intracranial Stents in US$ Thousands. The report provides separate comprehensive analytics for the US, Europe, and Rest of World. Annual estimates and forecasts are provided for the period 2013 through 2020. Also, a seven-year historic analysis is provided for these markets. Market data and analytics are derived from primary and secondary research. Company profiles are primarily based on public domain information including company URLs. The report profiles 14 companies including many key and niche players such as -

Admedes Schuessler GmbH
BALT Extrusion
Cardiatis SA
Codman & Shurtleff, Inc.
Covidien PLC

Table Of Contents

World Intracranial Stents Industry



I. INTRODUCTION, METHODOLOGY and PRODUCT DEFINITIONS

Study Reliability and Reporting Limitations I-1
Disclaimers I-2
Data Interpretation and Reporting Level I-2
Quantitative Techniques and Analytics I-3
Product Definitions and Scope of Study I-3


II. EXECUTIVE SUMMARY

1. INDUSTRY OVERVIEW II-1
Growing Importance of Intracranial Stents in Neurovascular
Disease II-1
Table 1: Global Neurovascular Intervention Market by
Technique (2014): Percentage Share Breakdown for
Embolization, Revascularization, Support Devices, and
Mechanical Thrombectomy (includes corresponding Graph/Chart) II-1
The Global Intracranial Stents Market - Adversely Impacted by
the SAMMPRIS Study II-2
SAMMPRIS Study: An Insight II-3
Rising Geriatric Population - A Major Growth Driver for the
ICS Market II-4
Table 2: Elderly Population (65+ Years) as a Percentage of
the Total Population: 2000 and 2025 (includes corresponding
Graph/Chart) II-5

Table 3: Global Population Statistics for the 65+ Age Group:
2012 (includes corresponding Graph/Chart) II-6

Table 4: Life Expectancy at Age 60 and 80 Years- (2010-2015),
(2020-2025) and (2045-2050) (includes corresponding
Graph/Chart) II-7
Market Challenges II-7
Technological Challenges II-7
Safety and Efficacy II-7
Regulatory Challenges II-8
Price Factor II-8

2. INTRACRANIAL STENTS AVAILABLE IN THE MARKET II-9
APOLLO Stent System II-9
WILLIS® Intracranial Stent Graft System II-9
Neuroform EZ® Stent System II-9
Wingspan® Stent System II-9
Self-Expandable LEO II-10
Micrus® Pharos™ Vitesse™ Intracranial Stent II-10
Solitaire AB Neurovascular Remodeling Device II-10

3. MARKET DRIVERS and TRENDS II-11
Changing Lifestyle Conditions Stoking Risk of Cerebrovascular
Diseases II-11
Rising Stroke Statistics - An Opportunity Indicator II-11
Rising Number of Restenosis Cases Boosts Demand for Stenting II-12
Asians at Highest Risk of Intracranial Atherosclerosis Disease II-12
Cardiovascular Stent Manufacturers Diversify Into the
Neurovascular Market II-12
QMRA Facilitates Detection of In-stent Stenosis II-13
MNCs Weave Strategies to Tap Growth Centers in Emerging Markets II-13
Medical Tourism Buoys Demand for Stenting Procedures in
Emerging Nations II-14
Rising Road Accidents Lead to Increasing Number of Stenting
Procedures II-14
Table 5: Global Rate of Road Fatalities by Economic Status of
Countries (2014): Percentage Rate of Road Fatalities per
100,000 Residents for Low, Mid and High Per Capita Income
Regions (includes corresponding Graph/Chart) II-15

4. PRODUCT OVERVIEW II-16
Intracranial Stenting II-16
Stents II-16
Evolution II-16
Types of Stents II-17
Bare Metal Stents (BMS) II-17
Drug Eluting Stents II-17
Self-Expanding Stents II-18
Post-Treatment Management II-18
Anti-Platelet Therapy II-18
Surveillance Imaging II-19

5. NEUROVASCULAR DISEASES - AN OVERVIEW II-20
Introduction II-20
Diagnosis of Intracranial Stenosis II-20
Differential Diagnosis II-20
Neuroimaging Screening II-21
Anatomic Diagnosis II-21
Digital Subtraction Angiography II-21
Transcranial Doppler II-21
Magnetic Resonance Angiography (MRA) II-21
Positron Emission Tomography (PET) II-22
Computerized Tomography (CT) Perfusion II-22
Treatment Procedures for Intracranial Stenosis II-22
Medication II-22
Anticoagulants or Blood Thinners II-22
Cholesterol Lowering Drugs II-22
Blood Pressure Medications II-23
Surgical Procedures II-23
Stenting/Balloon Angioplasty II-23
Cerebral Artery Bypass II-23

6. MAJOR NEUROVASCULAR INDICATIONS REQUIRING STENTING PROCEDURES II-24
Ischemic Stroke II-24
Symptoms, Indications, and Complications Associated with Stroke II-24
Posterior Circulation Stroke II-24
Anterior Circulation Stroke II-24
Non-Specific Signs II-24
Some Major Risk Factors for Stroke II-24
Intracranial Atherosclerotic Disease (ICAD) II-25
Risk Factors II-25
Treatment Options for ICAD II-25
Brain Aneurysms/Cerebral Aneurysm/ Intracranial Aneurysm II-26
Aneurysm - Quick Facts II-26
Symptoms of Unruptured Aneurysm II-26
Risk Factors for Aneurysm II-26
Detection Methods II-27
Table 6: Comparison of Sensitivity and Specificity of
Computed Tomography Angiography (CTA), Transcranial Doppler
Sonography (TCD) and Magnetic Resonance Angiography (MRA) in
the Diagnosis of Intracranial Aneurysms (includes
corresponding Graph/Chart) II-27

Table 7: Percentage Mortality, Morbidity, and Re-bleeding
Rate of Intervention Associated with Intracranial Aneurysms II-28
Arterial Dissection II-28
Diagnosis II-28
Treatment II-28
Restenosis II-28

7. PRODUCT INTRODUCTIONS and APPROVALS II-29
CFDA Approves New Specifications of MicroPort's Apollo Stent
System (China) II-29
MicroPort's WILLIS® Intracranial Stent Graft System Receives
China SFDA Approval II-29
Phenox's pCONus Bifurcation Aneurysm Implant Obtains CE-Mark
Approval II-29
Acandis' Acclino 1.9-F Stent System Receives CE Mark Approval II-29
ITGI Medical Obtains CE Mark Approval for AneuGraft Nx II-29

8. RECENT INDUSTRY ACTIVITY II-30
MicroVention Enrolls in Clinical Trial for Its FREDâ„¢ System (US) II-30
Admedes Schuessler to Expand Nitinol Manufacturing Capacity II-30
STAR Study Results Establish Safety and Efficacy of Solitaireâ„¢
FR Device in Acute Ischemic Stroke Treatment II-30
MicroPort Scientific Announces Inauguration of MicroPort
NeuroTech II-30
Purdue University Scientists Study Stents Coated with
Nanotechnology-Enhanced Drug for Treatment of Aneurysms II-30

9. FOCUS ON SELECT PLAYERS II-31
Admedes Schuessler GmbH (Germany) II-31
BALT Extrusion (France) II-31
Cardiatis SA (Belgium) II-31
Codman and Shurtleff, Inc. (US) II-32
Covidien PLC (Ireland) II-32
ITGI Medical Ltd. (Israel) II-33
MicroPort Scientific Corporation (China) II-33
OBEX Medical (New Zealand) II-34
Stryker Corp. (US) II-34

10. GLOBAL MARKET PERSPECTIVE II-35
Table 8: World Recent Past, Current and Future Analysis for
Intracranial Stents by Geographic Region - US, Europe and Rest
of World Markets Independently Analyzed with Annual Sales
Figures in US$ Thousand for the Years 2013 through 2020
(includes corresponding Graph/Chart) II-35

Table 9: World Historic Review for Intracranial Stents by
Geographic Region - US, Europe and Rest of World Markets
Independently Analyzed with Annual Sales Figures in US$
Thousand for the Years 2006 through 2012 (includes
corresponding Graph/Chart) II-36

Table 10: World 14-Year Perspective for Intracranial Stents by
Geographic Region - Percentage Breakdown of Dollar Sales for
US, Europe and Rest of World Markets for the Years 2006, 2014 and
2020 (includes corresponding Graph/Chart) II-37


III. MARKET

1. THE UNITED STATES III-1
A.Market Analysis III-1
The Largest Market for Intracranial Stents Globally III-1
SAMMPRIS Study Results - A Major Blow to the US ICS Market III-1
Ageing Demographics: A Key Market Driver III-3
Table 11: North American Elderly Population by Age Group:
1975-2050 (includes corresponding Graph/Chart) III-3
Regulatory Status of Intracranial Stents in the United States III-4
Intracranial Stenting among Medicare Beneficiaries during
the Years 2006-2010 III-4
Strategic Corporate Developments III-4
Select Key Players III-5
B.Market Analytics III-7
Table 12: The US Recent Past, Current and Future Analysis for
Intracranial Stents Market Analyzed with Annual Sales
Figures in US$ Thousand for the Years 2013 through 2020
(includes corresponding Graph/Chart) III-7

Table 13: The US Historic Review for Intracranial Stents
Market Analyzed with Annual Sales Figures in US$ Thousand
for the Years 2006 through 2012 (includes corresponding
Graph/Chart) III-8

2. EUROPE III-9
A.Market Analysis III-9
Negative Effects of SAMMPRIS Study Expand to European Market III-9
Increasing Geriatric Population Segment: A Business Case for
ICS III-9
Table 14: Population Breakup by Age Group for Select
European Countries: 2012 (As a % of Total Population)
(includes corresponding Graph/Chart) III-10
Focus on Select Regional Markets III-11
France III-11
French Government Imposes Regulations on Advertisement of
High-risk Medical Devices III-11
The United Kingdom III-11
Stroke Statistics in the UK III-11
Table 15: Breakdown of Total Number of Deaths Due to
Strokes by Age and Sex in the UK: 2010 (includes
corresponding Graph/Chart) III-11
Product Approvals III-12
Strategic Corporate Development III-12
Select Key Players III-12
B.Market Analytics III-14
Table 16: European Recent Past, Current and Future Analysis
for Intracranial Stents Market Analyzed with Annual Sales
Figures in US$ Thousand for the Years 2013 through 2020
(includes corresponding Graph/Chart) III-14

Table 17: European Historic Review for Intracranial Stents
Market Analyzed with Annual Sales Figures in US$ Thousand
for the Years 2006 through 2012 (includes corresponding
Graph/Chart) III-15

3. REST OF WORLD III-16
A.Market Analysis III-16
Developing Regions Poised to Witness Faster Growth III-16
Price Sensitivity of Asian Consumers - A Crucial Factor III-16
India and China Offer Significant Growth Opportunities III-16
Table 18: China and India Leads Global Population (July
2013): Table Depicting China and India's Huge Population
Vis-a-vis Other Countries' Population (in Million) by Age
Group (includes corresponding Graph/Chart) III-17

Table 19: Age-wise Breakup of China and India's Population
Vis-a-vis Other Populous Countries Globally: As of July
2013 (includes corresponding Graph/Chart) III-18
Select Regional Markets III-18
Australia III-18
Stroke Statistics in Australia III-18
Table 20: Stroke Prevalence in Australia Age and Gender:
2012 (includes corresponding Graph/Chart) III-19
Leading Risk Factors for Stroke-Related Fatalities:
Ranking Based on Number of Deaths (2012) III-19
China III-19
Healthcare Reforms and New Product Approval to Propel
Market Growth III-19
Table 21: Chinese Neurovascular Stents Market by Leading
Brand (2013): Percentage Market Share Breakdown of Units
Sold for Apollo, Wingspan, and Others (includes
corresponding Graph/Chart) III-20
APOLLO - Tried and tested Stent System III-20
WILLIS® to Target Bright Market Prospects in China III-20
India III-21
Changes in Lifestyle Demographic and Socioeconomic Factors
Increase Stroke Prevalence III-21
Stroke Statistics III-21
Management and Treatment of Stroke Presents a Daunting Task III-21
Kerala - Gaining Prominence for Neurovascular Therapy III-21
Japan III-22
Japanese Intracranial Stents Market III-22
Table 22: Japanese Elderly (65+ Years) Population:
2000-2020 (includes corresponding Graph/Chart) III-22
Studies Validate Effectiveness of Endovascular Therapy for
Treatment of Intracranial Aneurysm III-23
Product Approvals III-23
Strategic Corporate Development III-24
Select Key Players III-24
B.Market Analytics III-26
Table 23: Rest of World Recent Past, Current and Future
Analysis for Intracranial Stents Market Analyzed with Annual
Sales Figures in US$ Thousand for the Years 2013 through
2020 (includes corresponding Graph/Chart) III-26

Table 24: Rest of World Historic Review for Intracranial
Stents Market Analyzed with Annual Sales Figures in US$
Thousand for the Years 2006 through 2012 (includes
corresponding Graph/Chart) III-27


IV. COMPETITIVE LANDSCAPE

Total Companies Profiled: 14 (including Divisions/Subsidiaries - 17)

The United States (6)
Europe (6)
- France (1)
- Germany (3)
- Rest of Europe (2)
Asia-Pacific (Excluding Japan) (4)
Middle East (1)

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