Global Next Generation Sequencing Informatics Market

  • October 2013
  • -
  • Frost & Sullivan
  • -
  • 68 pages

Informatics Vendors Flock to Growth in Sequencing Adoption

More than 100 companies participate in the global next generation sequencing (NGS) informatics market. This research service evaluates the market from 2012 to 2018. The research covers key market drivers and restraints, analysis of the changing competitive landscape, revenue forecasts, and the important trends that affect market growth. Also included are profiles for many of the leading NGS informatics services providers, commercial primary and secondary data analysis tools vendors, commercial biological interpretation and clinical reporting tools vendors, and NGS LIMS vendors. Lastly, this analysis discusses 3 major market predictions and implications for market competitors.

Executive Summary

Total Market Overview
• Global sales of next generation sequencing (NGS) informatics products and services generated approximately $X million in 2012 and will reach $X million in 2018 with a compound annual growth rate (CAGR) of X% from 2012 to 2018. Revenue growth is primarily driven by sales of tertiary data analysis tools employed for biological interpretation and clinical reporting.
• More than X% of NGS informatics revenues come from customers in translational biomedical research organizations including academic institutions, government agencies, and biopharmaceutical companies.
• More than X companies participate in the NGS informatics market. These companies fall into X of X categories:
- Traditional information technology vendors and companies provide big data solutions. These companies entered the NGS informatics market with computing or storage products (e.g., EMC Isilon, IBM, Dell).
- Sequencing technology vendors offer their own informatics solutions that are developed specifically for their platforms (e.g., Illumina, Life Technologies).
- Sequencing services providers offer bioinformatics as a component to their overall service offering (e.g., BGI, Beckman Coulter Genomics).
- Informatics tool vendors, many that entered the market in the late 1990s, provide solutions for analyzing microarray data, (e.g., Ingenuity Systems, Partek, DNASTAR).
- Also included are laboratory information management systems (LIMS) vendors (e.g., GenoLogics, Sapio Sciences).
- NGS informatics consulting services providers (e.g., BioTeam, Eagle Genomics) are included.
- Recent market entrants offer bioinformatic solutions (software, cloud-based platforms, and pre-loaded appliances) developed specifically for NGS applications (e.g., DNAnexus, Knome, Real Time Genomics).

Summary of Competitor Types

Competitor Profile: Traditional Information Technology Vendors
• Recognized brand name
• Big data expertise
• Large sales force
• Multinational presence
Examples:
• Amazon Web Services
• Dell
• EMC
• IBM
• Microsoft
• Oracle
Products:
• Cloud services
• High performance scientific computing cores
• High capacity scalable storage systems
• Database management systems
• Other computer hardware systems and software products

Competitor Profile: Sequencing Technology Vendors
• Well-established NGS market presence
• Extensive partnerships with other NGS informatics vendor types
Examples:
• Illumina
• Life Technologies
Products:
• NGS instruments and consumables
• Informatics solutions that are developed specifically for their platforms
• Cloud-based platforms

Competitor Profile: Sequencing Services Providers
• Extensive sequencing and bioinformatics expertise and resources
• Experience with diverse range of project types and applications
Examples:
• Beckman Coulter Genomics
• BGI
• Edge Bio
• PerkinElmer
Products:
• Multiple sequencing applications: whole genome, exome, targeted, microbial, RNA-seq
• Bioinformatics services ranging from providing raw reads to full analysis

Competitor Profile: Informatics Tool Vendors
• Established genomics customer base
• Recognized brand for genomics informatics
• Broad portfolio of informatics solutions
• Well-developed and curated databases
Examples:
• BIOBASE
• DNASTAR
• Genomatix
• Ingenuity Systems
• Partek
Products:
• Genomics, microarray, and NGS data analysis software and databases
• Cloud-based NGS informatics platforms
• Pre-loaded appliances for NGS informatics

Competitor Profile: NGS Informatics Solution Vendors
• Exclusive focus on NGS
• NGS informatics expertise
• Innovative solutions and pricing models
• Significant venture capital backing
Examples:
• Bina Technologies
• CLC Bio
• DNAnexus
• Knome
• Real Time Genomics
Products:
• NGS data analysis software
• Cloud-based NGS informatics platforms
• Pre-loaded appliances for NGS informatics

Competitor Profile: LIMS Vendors
• LIMS expertise
Examples:
• GenoLogics
• Sapio Sciences
Products:
• LIMS for sample data management
• Electronic laboratory notebook (ELN)

Competitor Profile: NGS Informatics Consulting Services Providers
• NGS informatics expertise
• Strong customer relationships
Examples:
• BioTeam
• Eagle Genomics
Products:
• NGS informatics solutions that are tailored to individual customers’ needs

CEO’s Perspective

1. Market growth is primarily driven by sales of tertiary data analysis tools for biological interpretation and clinical reporting.
2. Customers remain incredibly fragmented in terms of their applications, pipelines, and NGS informatics needs.
3. The competitor base is expected to shrink as vendors with “me too” solutions begin exiting the market.
4. Vendors must overcome the challenge associated with customers’ reliance on their internal bioinformatics resources.

Key Questions This Study Will Answer

• Given the great diversity of customer needs, which NGS informatics solutions will ultimately provide the most value?
• To what extent are customers likely to migrate away from open-source tools in favor of commercial NGS informatics solutions?
• What role is the cloud likely to play in the NGS market over the next 3 to 5 years?
• How will the increasing utilization of clinical sequencing influence the NGS informatics market?
• How will the competitive landscape settle-out as the NGS informatics market matures?
• What are the competitor profiles in this market and how do market participants compete for market share?

Table Of Contents

Table of Contents

1. Executive Summary
• Executive Summary
• Market Engineering Measurements
• Summary of Competitor Types
• CEO’s Perspective
2. Market Overview
• Definitions
• Key Questions This Study Will Answer
3. External Challenges: Drivers and Restraints—Total NGS Informatics Market
• Drivers and Restraints
• Drivers Explained
• Restraints Explained
4. Forecast and Trends-Total NGS Informatics Market
• Market Engineering Measurements
• Forecast Assumptions
• Revenue Forecast
• Revenue Forecast Discussion
• Percent Revenue by Region
• Breakdown by Product Segment
• Percent Revenue by Product Segment
• Revenue by Product Segment Discussion
5. Competitive Analysis
• Competitive Environment
• Key Vendor Metrics
6. The Last Word—3 Big Predictions
7. Appendix

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