MediPoint: Electrophysiology - EU Analysis and Market Forecasts

Summary

Still in its infancy, the electrophysiology (EP) device market has seen significant adoption; as more physicians become experienced in diagnostic and ablation techniques, increasing numbers of hospitals purchase supportive equipment, device price-points fall, and efficacy improves. This continued growth is also driven by technological advancements including the emergence of next-generation ablation technologies, improvements in catheter diagnostics, and advancements in lab systems. Further, as imaging modalities improve, patients are exposed to less radiation than ever before, which will only further drive diagnostics.

The EP market is dominated by several key players, with the biggest markets being in the US and European Union (EU). With improvements in reimbursement worldwide, as well as advancements of global distribution channels, devices are being sold in more hospitals and ever, and this is only expected to increase. With only a few key players currently in the market, competition remains high as industry leaders fight for valuable market share.

Scope

- An overview of electrophysiology, which includes epidemiology, etiology, symptoms, diagnosis, pathology and treatment guidelines.
- Annualized EU electrophysiology market revenue from 2005 to 2013, forecast for 7 years to 2020.
- Investigation of current and future market competition for electrophysiology
- Insightful review of the key industry drivers, restraints and challenges as well as predicted impact of key events.
- Competitor assessment including device approval analysis and device sales forecasts.
- Marketed and pipeline product profiles covering efficiency, safety, clinical study details, device approvals, product positioning and device sales forecast.
- Analysis of unmet needs within the market and opportunities for future players.
- Technology trends evaluation to assess strength of pipeline.
- An overview of all devices in development including clinical study details, design and material selection considerations, efficacy reports, and device approval timelines.
- Company profiles including business description, financial overview and SWOT analysis.
- Coverage of key market players.
- Strategic assessment of the electrophysiology sector through market impact analysis, future market scenario and company analysis.
- Direct quotes from Key Opinion Leaders (KOL)

Reasons to buy

- Understand the trends shaping and driving EU electrophysiology market.
- Realize device preferences of physicians who have performed the tests already.
- Access market sizing, forecasts and quantified growth opportunities in the EU electrophysiology market through 2020.
- Quantify candidate patient populations to better design product pricing & launch plans.
- Drive revenues, formulate effective sales and marketing strategies and gain in-depth understanding of the competitive landscape.
- Perform benchmarking analysis of growth opportunities against currently marketed products.
- Assess competitiveness of products in market by understanding the strengths and weaknesses of current competition.
- Take a comprehensive look at the market’s device pipeline and identify promising, paradigm-shifting products.
- Create an effective counter-strategy to gain a competitive advantage against those currently in the market.
- Organize your sales and marketing efforts by identifying the market categories and segments that present the best opportunities for growth.
- What’s the next big thing in the EU electrophysiology market landscape? Identify, understand and capitalize.

Table Of Contents

1 Table of Contents

2 Introduction 23
2.1 Catalyst 23
2.2 Related Reports 23
3 Industry Overview 24
3.1 Introduction 24
3.2 Anatomy and Physiology 24
3.2.1 Etiology 25
3.2.2 Risk Factors 26
3.2.3 Types of Arrhythmia 27
3.3 Clinical Presentation 30
3.3.1 Symptoms 30
3.4 Diagnosis 30
3.4.1 Blood and Urine Diagnostic Procedures 31
3.4.2 Electrocardiography-Based Diagnostic Procedures 31
3.4.3 Computerized Tomographic Angiography 32
3.4.4 Electrophysiological Testing 32
3.4.5 Electromechanical Wave Imaging 33
3.4.6 Echocardiography 33
3.4.7 Tilt-Taable Testing 33
3.4.8 Diagnostic and Electrophysiological Studies 34
3.4.9 New York Heart Association Scale 34
3.4.10 American College of Cardiology Scale 34
3.5 Epidemiology 35
3.5.1 Prevalence 35
3.6 Market Segmentation 38
3.6.1 Electrophysiology Diagnostic Catheter 38
3.6.2 Electrophysiology Ablation Catheter 39
3.6.3 Electrophysiology Lab Systems 53
3.7 Treatment Costs, Pricing, and Reimbursement 53
3.7.1 Direct Costs 56
3.7.2 Indirect Costs 58
3.7.3 US Costs 60
3.7.4 Pricing of Electrophysiology Devices and Equipment 62
3.7.5 Reimbursement 63
3.8 Market Characterization 68
3.8.1 Growing Patient Population Suitable for Treatment 68
3.8.2 Increasing Prevalence of Arrhythmia with Age 69
3.8.3 Emergence of Remote Catheter Navigation and Ablation Technology 71
3.8.4 Focus on the Development of “Single Shot” Devices 74
3.8.5 Catheter Localization Aided by Novel Mapping and Visualization Techniques 75
3.8.6 Electrophysiology Market Trends in Inorganic Growth through Consolidation 76
3.8.7 Lack of Skilled and Experienced Electrophysiologists to Negatively Impact Procedure Volumes and Hinder Market Growth 76
3.8.8 Awareness and Education to Drive Earlier Intervention 77
3.9 Regulatory Issues and Recalls 78
4 Segment Analysis 79
4.1 Ablation Catheters Market Dynamics 79
4.1.1 Ablation Catheters Market Drivers 79
4.1.2 Ablation Catheters Market Barriers 96
4.2 Diagnostic Catheters Market Dynamics 107
4.2.1 Diagnostic Catheters Market Drivers 107
4.2.2 Diagnostic Catheters Market Barriers 108
4.3 Lab Systems Market Dynamics 111
4.3.1 Lab Systems Market Drivers 111
4.3.2 Lab Systems Market Barriers 113
5 Market Outlooks by Geography 115
5.1 France 115
5.1.1 Overview 115
5.1.2 Market Analysis 118
5.2 Germany 126
5.2.1 Overview 126
5.2.2 Market Analysis 127
5.3 Italy 135
5.3.1 Overview 135
5.3.2 Market Analysis 136
5.4 Spain 144
5.4.1 Overview 144
5.4.2 Market Analysis 146
5.5 UK 156
5.5.1 Overview 156
5.5.2 Market Analysis 157
6 Strategic Competitive Assessment 166
6.1 Key Company Share 166
6.1.1 Overview 166
6.1.2 France 167
6.1.3 Germany 168
6.1.4 Italy 169
6.1.5 Spain 170
6.1.6 UK 171
7 Current and Future Players 173
7.1 Biosense Webster 173
7.1.1 Overview 173
7.1.2 Portfolio Evaluation 173
7.1.3 Biosense Webster SWOT Analysis 174
7.2 Biotronik 178
7.2.1 Overview 178
7.2.2 Portfolio Evaluation 178
7.2.3 Biotronik SWOT Analysis 179
7.3 Boston Scientific 183
7.3.1 Overview 183
7.3.2 Boston Scientific Acquires Bard EP and Rhythmia Medical 184
7.3.3 Portfolio Evaluation 184
7.3.4 Boston Scientific SWOT Analysis 188
7.4 CardioFocus 194
7.4.1 Overview 194
7.4.2 Portfolio Evaluation 195
7.4.3 Company SWOT Analysis 196
7.5 CardioInsight 199
7.5.1 Overview 199
7.5.2 Portfolio Evaluation 199
7.5.3 CardioInsight SWOT Analysis 200
7.6 Hansen Medical 202
7.6.1 Overview 202
7.6.2 Portfolio Evaluation 203
7.6.3 Company SWOT Analysis 203
7.7 Imricor 206
7.7.1 Overview 206
7.7.2 Portfolio Evaluation 207
7.7.3 Company SWOT Analysis 207
7.8 Japan Lifeline 210
7.8.1 Overview 210
7.8.2 Portfolio Evaluation 211
7.8.3 Company SWOT Analysis 211
7.9 Magnetecs Corporation 214
7.9.1 Overview 214
7.9.2 Portfolio Evaluation 214
7.9.3 Company SWOT Analysis 215
7.10 Medtronic 217
7.10.1 Overview 217
7.10.2 Portfolio Evaluation 218
7.10.3 Company SWOT Analysis 222
7.11 MicroPort Scientific Company 226
7.11.1 Overview 226
7.11.2 Portfolio Evaluation 226
7.11.3 MicroPort Scientific SWOT Analysis 227
7.12 St. Jude Medical 230
7.12.1 Overview 230
7.12.2 Portfolio Evaluation 230
7.12.3 Company SWOT Analysis 233
7.13 Stereotaxis 236
7.13.1 Overview 236
7.13.2 Portfolio Evaluation 236
7.13.3 Commercial Positioning 237
7.13.4 Company SWOT Analysis 238
7.14 Stryker Sustainability Solutions 244
7.14.1 Overview 244
7.14.2 Portfolio Evaluation 245
7.14.3 Company SWOT Analysis 246
7.15 Topera Medical 248
7.15.1 Overview 248
7.15.2 Portfolio Evaluation 249
7.15.3 Company SWOT Analysis 250
8 Pipeline Product Assessment 253
8.1 Pipeline Assessment by Development Stage 253
8.2 Segment Analysis of Pipeline Products 254
8.2.1 Ablation Catheter Pipeline Products 254
8.2.2 Diagnostic Catheter Pipeline Products 260
8.3 Lab Systems 261
8.3.1 Integrated X-Ray and Robotic Catheter System (Hansen Medical, Philips Healthcare) 261
8.3.2 ClearTrace System (MRI Interventions) 262
8.3.3 Robotic Catheter Guidance Lab System (North Carolina State University) 262
8.3.4 Catheter Guidance Lab System (SCR) 263
9 Strategic Deals Analysis 264
9.1 Key Acquisitions 264
9.1.1 Boston Scientific Acquires C.R. Bard’s Electrophysiology Business for $275m 264
9.1.2 St. Jude Medical Acquires Endosense for $161m 264
9.1.3 Boston Scientific Acquires Rhythmia Medical for $265m 265
9.2 Key Partnerships 265
9.2.1 Philips and Biosense Webster Technology Integration Agreement 265
9.2.2 Biosense Webster Technology Integration Agreement with GE Healthcare Systems and Siemens Healthcare 265
9.2.3 Abbott and St. Jude Medical Broaden Alliance in US Cardiovascular Device Market 266
10 Appendix 267
10.1 Bibliography 267
10.2 Abbreviations 278
10.3 Report Methodology 283
10.3.1 Overview 283
10.3.2 Coverage 283
10.3.3 Secondary Research 283
10.3.4 Forecasting Methodology 284
10.3.5 Primary Research - Key Opinion Leader Interviews 285
10.3.6 Expert Panel Validation 285
10.4 Physicians Included in this Study 286
10.5 About the Authors 288
10.5.1 Analysts 288
10.5.2 Global Head of Healthcare 289
10.6 About MediPoint 290
10.7 About GlobalData 290
10.8 Disclaimer 290

1.1 List of Tables

Table 1: New York Heart Association Scale 34
Table 2: American College of Cardiology Scale 35
Table 3: Prevalent Cases of Congestive Heart Failure, EU, Ages ?45 Years, Men and Women (N), 2012-2019 38
Table 4: Atrial Fibrillation Treatment Goals 40
Table 5: Reasons for Lack of Consensus on Site for Ablation 45
Table 6: Techniques for Treatment of Persistent and Permanent Atrial Fibrillation 47
Table 7: Types of Atrial Fibrillation based of Triggers 49
Table 8: Characteristics of Catheter Ablation by Arrhythmia Type (%) 50
Table 9: Rates of Occurrence of Major Complications with Catheter Ablation (%), 2003-2006 51
Table 10: Catheter Ablation Success for the Treatment of Atrial Fibrillation (%), Global, 1995-2002 and 2003-2006 52
Table 11: Catheter Ablation Success by Arrhythmia Type (%), 2009 53
Table 12: Classes of Recommendations 54
Table 13: Level of Evidence 54
Table 14: Estimation of Total Incremental Health Care Costs in Patients with Atrial Fibrillation ($), US, 2008 60
Table 15: Complications Associated with Atrial Fibrillation and Their Incremental Medicare Costs, US, 2008 62
Table 16: Average Selling Price of Electrophysiology Products by Type, Global, 2013 63
Table 17: Percentage of Population Age 65 and Older, by Country, 2005-2015 69
Table 18: Overview of the Applications, Benefits, Limitations, and Future Directions of Remote Navigation Systems in Electrophysiology 73
Table 19: Key Acquisitions in the Electrophysiology Devices Market 76
Table 20: Advantages and Disadvantages of Various Energy Sources Used for Catheter Ablation 87
Table 21: Experimental Theories of How Atrial Fibrillation Perpetuates 94
Table 22: Antiarrhythmic Drug Classification by Mode of Action 98
Table 23: Major Complications Associated with Catheter Ablation 101
Table 24: Complications Associated with Catheter Ablation 101
Table 25: Recently Approved and Investigational Antiarrhythmic Drugs Under Development 102
Table 26: Diagnosed Patient Volume by Disease Type, Diagnosed Patients (N), France, 2013 119
Table 27: Ablation Catheters Market, France, Historic Revenue ($m), 2005-2013 120
Table 28: Ablation Catheters Market, France, Forecast Revenue ($m), 2013-2020 121
Table 29: Diagnostic Catheters Market, France, Historic Revenue ($m), 2005-2013 122
Table 30: Diagnostic Catheters Market, France, Forecast Revenue ($m), 2013-2020 123
Table 31: Lab Systems Market, France, Historic Revenue ($m), 2005-2013 124
Table 32: Lab Systems Market, France, Forecast Revenue ($m), 2013-2020 125
Table 33: Diagnosed Patient Volume by Disease Type, Diagnosed Patients (N), Germany, 2013 128
Table 34: Ablation Catheters Market, Germany, Historic Revenue ($m), 2005-2013 129
Table 35: Ablation Catheters Market, Germany, Forecast Revenue ($m), 2013-2020 130
Table 36: Diagnostic Catheters Market, Germany, Historic Revenue ($m), 2005-2013 131
Table 37: Diagnostic Catheters Market, Germany, Forecast Revenue ($m), 2013-2020 132
Table 38: Lab Systems Market, Germany, Historic Revenue ($m), 2005-2013 133
Table 39: Lab Systems Market, Germany, Forecast Revenue ($m), 2013-2020 134
Table 40: Diagnosed Patient Volume by Disease Type, Diagnosed Patients (N), Italy, 2013 137
Table 41: Ablation Catheters Market, Italy, Historic Revenue ($m), 2005-2013 138
Table 42: Ablation Catheters Market, Italy, Forecast Revenue ($m), 2013-2020 139
Table 43: Diagnostic Catheters Market, Italy, Historic Revenue ($m), 2005-2013 140
Table 44: Diagnostic Catheters Market, Italy, Forecast Revenue ($m), 2013-2020 141
Table 45: Lab Systems Market, Italy, Historic Revenue ($m), 2005-2013 142
Table 46: Lab Systems Market, Italy, Forecast Revenue ($m), 2013-2020 143
Table 47: Diagnosed Patient Volume by Disease Type, Diagnosed Patients (N), Spain, 2013 150
Table 48: Ablation Catheters Market, Spain, Historic Revenue ($m), 2005-2013 151
Table 49: Ablation Catheters Market, Spain, Forecast Revenue ($m), 2013-2020 151
Table 50: Diagnostic Catheters Market, Spain, Historic Revenue ($m), 2005-2013 152
Table 51: Diagnostic Catheters Market, Spain, Forecast Revenue ($m), 2013-2020 153
Table 52: Lab Systems Market, Spain, Historic Revenue ($m), 2005-2013 154
Table 53: Lab Systems Market, Spain, Forecast Revenue ($m), 2013-2020 155
Table 54: Diagnosed Patient Volume by Disease Type, Diagnosed Patients (N), UK, 2013 158
Table 55: Ablation Catheters Market, UK, Historic Revenue ($m), 2005-2013 159
Table 56: Ablation Catheters Market, UK, Forecast Revenue ($m), 2013-2020 160
Table 57: Diagnostic Catheters Market, UK, Historic Revenue ($m), 2005-2013 161
Table 58: Diagnostic Catheters Market, UK, Forecast Revenue ($m), 2013-2020 162
Table 59: Lab Systems Market, UK, Historic Revenue ($m), 2005-2013 163
Table 60: Lab Systems Market, UK, Forecast Revenue ($m), 2013-2020 164
Table 61: Company Share, France, Total Electrophysiology Market Revenue (%), 2012 168
Table 62: Company Share, Germany, Total Electrophysiology Market Revenue (%), 2012 169
Table 63: Company Share, Italy, Total Electrophysiology Market Revenue (%), 2012 170
Table 64: Company Share, Spain, Total Electrophysiology Market Revenue (%), 2012 171
Table 65: Company Share, UK, Total Electrophysiology Market Revenue (%), 2012 172
Table 66: Company Profile - Biosense Webster 173
Table 67: Biosense Webster, Electrophysiology Devices Portfolio 174
Table 68: SWOT Analysis - Biosense Webster 174
Table 69: Company Profile - Biotronik 178
Table 70: Biotronik, Electrophysiology Devices Portfolio 179
Table 71: SWOT Analysis - Biotronik 179
Table 72: Company Profile - Boston Scientific 184
Table 73: Boston Scientific, Electrophysiology Devices Portfolio 187
Table 74: SWOT Analysis - Boston Scientific 188
Table 75: Company Profile - CardioFocus 195
Table 76: CardioFocus, Electrophysiology Devices Portfolio 196
Table 77: SWOT Analysis - CardioFocus 196
Table 78: Company Profile - CardioInsight 199
Table 79: CardioInsight, Electrophysiology Devices Portfolio 199
Table 80: SWOT Analysis - CardioInsight 200
Table 81: Company Profile - Hansen Medical 202
Table 82: Hansen Medical, Electrophysiology Devices Portfolio 203
Table 83: SWOT Analysis - Hansen Medical 203
Table 84: Company Profile - Imricor 206
Table 85: SWOT Analysis - Imricor 207
Table 86: Company Profile - Japan Lifeline 210
Table 87: Japan Lifeline, Electrophysiology Devices Portfolio 211
Table 88: SWOT Analysis - Japan Lifeline 211
Table 89: Company Profile - Magnetecs Corporation 214
Table 90: Magnetecs Corporation, Electrophysiology Devices Portfolio 215
Table 91: SWOT Analysis - Magnetecs Corporation 215
Table 92: Company Profile - Medtronic 218
Table 93: Medtronic, Electrophysiology Devices Portfolio, 2013 221
Table 94: SWOT Analysis - Medtronic 222
Table 95: Company Profile - MicroPort Scientific Company 226
Table 96: MicroPort Scientific, Electrophysiology Devices Portfolio 227
Table 97: SWOT Analysis - MicroPort Scientific 227
Table 98: Company Profile - St. Jude Medical 230
Table 99: St. Jude Medical, Electrophysiology Devices Portfolio 232
Table 100: SWOT Analysis - St. Jude Medical 233
Table 101: Company Profile - Stereotaxis 236
Table 102: Stereotaxis, Electrophysiology Devices Portfolio 238
Table 103: SWOT Analysis - Stereotaxis 239
Table 104: Company Profile - Stryker Sustainability Solutions 245
Table 105: Stryker Sustainability Solutions, Electrophysiology Devices Portfolio 245
Table 106: SWOT Analysis - Stryker Sustainability Solutions 246
Table 107: Company Profile - Topera Medical 249
Table 108: Topera Medical, Electrophysiology Devices Portfolio, 2013 249
Table 109: SWOT Analysis - Topera Medical 250
Table 110: Ablation Catheter Pipeline Products 253
Table 111: Diagnostic Catheter Pipeline Products 253
Table 112: Lab Systems Pipeline Products 253
Table 113: Catheter Ablation Device, Product Status 254
Table 114: Ablation Catheter Device - Transcutaneous Monitoring to Avoid Hypercapnea during Complex Catheter Ablations 255
Table 115: Apama Medical Ablation Catheter, Product Status 256
Table 116: Cooled Tip Catheter, Product Status 256
Table 117: MaPP-CS, Product Status 257
Table 118: ROF-AC, Product Status 257
Table 119: ROF-AS, Product Status 258
Table 120: Vision MR Ablation Catheter, Product Status 258
Table 121: Voyager Irrigated RFA Catheter, Product Status 259
Table 122: Navigation and Ablation Catheter, Product Status 259
Table 123: Hot Balloon Catheter, Product Status 260
Table 124: Lesion Assessment Device, Product Status 261
Table 125: Horizon MR Recording System, Product Status 261
Table 126: Integrated X-Ray and Robotic Catheter System, Product Status 262
Table 127: ClearTrace System, Product Status 262
Table 128: Robotic Catheter Guidance Lab System, Product Status 263
Table 129: Catheter Guidance Lab System, Product Status 263
Table 130: Key Acquisitions in the Electrophysiology Market 264

1.2 List of Figures
Figure 1: Types of Arrhythmia 27
Figure 2: Pulmonary Vein Ablation Procedure 42
Figure 3: Antiarrhythmic Drugs and/or Ablation for Rhythm Control in Atrial Fibrillation 55
Figure 4: Cost Comparison of Ablation versus Antiarrhythmic Drug Therapy, 2009 57
Figure 5: Breakdown of National Incremental Costs in patients with Atrial Fibrillation 61
Figure 6: Diagnosed Patient Volume by Disease Type, Diagnosed Patients (%), France, 2013 120
Figure 7: Ablation Catheters Market, France, Historic Revenue ($m), 2005-2013 121
Figure 8: Ablation Catheters Market, France, Forecast Revenue ($m), 2013-2020 122
Figure 9: Diagnostic Catheters Market, France, Historic Revenue ($m), 2005-2013 123
Figure 10: Diagnostic Catheters Market, France, Forecast Revenue ($m), 2013-2020 124
Figure 11: Lab Systems Market, France, Historic Revenue ($m), 2005-2013 125
Figure 12: Lab Systems Market, France, Forecast Revenue ($m), 2013-2020 126
Figure 13: Diagnosed Patient Volume by Disease Type, Diagnosed Patients (%), Germany, 2013 129
Figure 14: Ablation Catheters Market, Germany, Historic Revenue ($m), 2005-2013 130
Figure 15: Ablation Catheters Market, Germany, Forecast Revenue ($m), 2013-2020 131
Figure 16: Diagnostic Catheters Market, Germany, Historic Revenue ($m), 2005-2013 132
Figure 17: Diagnostic Catheters Market, Germany, Forecast Revenue ($m), 2013-2020 133
Figure 18: Lab Systems Market, Germany, Historic Revenue ($m), 2005-2013 134
Figure 19: Lab Systems Market, Germany, Forecast Revenue ($m), 2013-2020 135
Figure 20: Diagnosed Patient Volume by Disease Type, Diagnosed Patients (%), Italy, 2013 138
Figure 21: Ablation Catheters Market, Italy, Historic Revenue ($m), 2005-2013 139
Figure 22: Ablation Catheters Market, Italy, Forecast Revenue ($m), 2013-2020 140
Figure 23: Diagnostic Catheters Market, Italy, Historic Revenue ($m), 2005-2013 141
Figure 24: Diagnostic Catheters Market, Italy, Forecast Revenue ($m), 2013-2020 142
Figure 25: Lab Systems Market, Italy, Historic Revenue ($m), 2005-2013 143
Figure 26: Lab Systems Market, Italy, Forecast Revenue ($m), 2013-2020 144
Figure 27: Ablating Centers in Spain, 2001-2011 145
Figure 28: Ablation Procedures by Hospital Size and Type, 2012 145
Figure 29: Ablation Procedures by Target Substrate 146
Figure 30: Diagnosed Patient Volume by Disease Type, Diagnosed Patients (%), Spain, 2013 150
Figure 31: Ablation Catheters Market, Spain, Historic Revenue ($m), 2005-2013 151
Figure 32: Ablation Catheters Market, Spain, Forecast Revenue ($m), 2013-2020 152
Figure 33: Diagnostic Catheters Market, Spain, Historic Revenue ($m), 2005-2013 153
Figure 34: Diagnostic Catheters Market, Spain, Forecast Revenue ($m), 2013-2020 154
Figure 35: Lab Systems Market, Spain, Historic Revenue ($m), 2005-2013 155
Figure 36: Lab Systems Market, Spain, Forecast Revenue ($m), 2013-2020 156
Figure 37: Diagnosed Patient Volume by Disease Type, Diagnosed Patients (%), UK, 2013 159
Figure 38: Ablation Catheters Market, UK, Historic Revenue ($m), 2005-2013 160
Figure 39: Ablation Catheters Market, UK, Forecast Revenue ($m), 2013-2020 161
Figure 40: Diagnostic Catheters Market, UK, Historic Revenue ($m), 2005-2013 162
Figure 41: Diagnostic Catheters Market, UK, Forecast Revenue ($m), 2013-2020 163
Figure 42: Lab Systems Market, UK, Historic Revenue ($m), 2005-2013 164
Figure 43: Lab Systems Market, UK, Forecast Revenue ($m), 2013-2020 165
Figure 44: Company Share, France, Total Electrophysiology Market Revenue (%), 2012 168
Figure 45: Company Share, Germany, Total Electrophysiology Market Revenue (%), 2012 169
Figure 46: Company Share, Italy, Total Electrophysiology Market Revenue (%), 2012 170
Figure 47: Company Share, Spain, Total Electrophysiology Market Revenue (%), 2012 171
Figure 48: Company Share, UK, Total Electrophysiology Market Revenue (%), 2012 172

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