1. Market Research
  2. > Pharmaceutical
  3. > Therapy Market Trends
  4. > Ambirix (Prophylactic Hepatitis B Virus Vaccines) - Forecast and Market Analysis to 2022

Ambirix (Prophylactic Hepatitis B Virus Vaccines) - Forecast and Market Analysis to 2022

Summary

Hepatitis B, which is caused by the hepatitis B virus (HBV), is characterized by acute or chronic inflammation of the liver. Researchers and healthcare experts have estimated that roughly two billion people are infected with HBV worldwide, with roughly 600,000 people dying each year from HBV-related liver diseases. While the arrival of recombinant HBsAg vaccines has greatly reduced disease burden over the past two decades, questions surrounding vaccine uptake and effectiveness in adults, particularly in niche patient populations, still remain. GlobalData expects that the growing popularity of pediatric combination vaccines, along with the arrival of vaccines that achieve higher seroconversion rates in high-risk adults, will serve to stimulate growth in the marketplace over the forecast period. Country-specific immunization recommendations and policy implementation will be an essential metric for determining future vaccine uptake in the 7MM (US, France, Germany, Italy, Spain, UK, and Japan) and Canada.

Ambirix [Hepatitis A (Inactivated) & Hepatitis B (rDNA) Vaccine] is GSK’s bivalent combination vaccine that protects children and adolescents against disease caused by HAV and acute and chronic infections caused by all known strains of HBV. Ambirix contains the antigenic components used in GSK’s Havrix (formalin-inactivated HAV) and GSK’s Engerix-B (yeast-derived recombinant HBsAg). In 2002, Ambirix was approved in the 5EU for active immunization of children and adolescents 1–15 years of age utilizing a two-dose regimen for primary vaccination.

Scope

- Overview of Hepatitis B disease, including epidemiology, etiology, symptoms, diagnosis, pathology and treatment guidelines as well as an overview on the competitive landscape.
- Detailed information on Ambirix including product description, safety and efficacy profiles as well as a SWOT analysis.
- Sales forecast for Ambirix for the UK from 2012 to 2022.
- Sales information covered for the UK.

Reasons to buy

- Understand and capitalize by identifying products that are most likely to ensure a robust return
- Stay ahead of the competition by understanding the changing competitive landscape for Hepatitis B
- Effectively plan your M&A and partnership strategies by identifying drugs with the most promising sales potential
- Make more informed business decisions from insightful and in-depth analysis of Ambirix performance
- Obtain sales forecast for Ambirix from 2012-2022 in the UK.

Table Of Contents

Ambirix (Prophylactic Hepatitis B Virus Vaccines) - Forecast and Market Analysis to 2022
1 Table of Contents

2 Introduction 8
2.1 Catalyst 8
2.2 Related Reports 9
2.3 Upcoming Related Reports 11
3 Disease Overview 12
3.1 Overview 12
3.2 Etiology and Pathophysiology 13
3.2.1 Etiology 13
3.2.2 Pathophysiology 16
3.3 Symptoms 18
3.4 Prognosis 20
4 Vaccination Recommendations and Coverage Rates 21
4.1 Overview 21
5 Competitive Assessment 25
5.1 Overview 25
5.2 Strategic Competitor Assessment 25
6 Ambirix 28
6.1 Overview 28
6.2 Immunogenicity 29
6.3 Safety 30
6.4 SWOT Analysis 31
6.5 Forecast 32
7 Appendix 33
7.1 Bibliography 33
7.2 Abbreviations 47
7.3 Methodology 50
7.4 Forecasting Methodology 50
7.4.1 Patient Populations Targeted for Vaccination 51
7.4.2 Vaccination Coverage Rates 54
7.4.3 Vaccinated Patients 55
7.4.4 Regulatory Approval vs. Advisory Committee Recommendation 55
7.4.5 General Pricing Assumptions 56
7.4.6 Individual Vaccine Assumptions 57
7.5 Physicians and Specialists Included in this Study 58
7.5.1 Interviews of Key Opinion Leaders (KOLs) 58
7.5.2 Online Survey of High-Prescribing Physicians (non-KOLs) 60
7.6 About the Authors 61
7.6.1 Analyst 61
7.6.2 Therapy Area Director 61
7.6.3 Global Head of Healthcare 62
7.7 About GlobalData 63
7.8 Disclaimer 63

1.1 List of Tables

Table 1: Modes of HBV Transmission 17
Table 2: HBV Serological Markers and Test Interpretations 18
Table 3: Symptoms of HBV Infection 19
Table 4: HBV Vaccination Advisory Committees by Country 22
Table 5: HBV Immunization Recommendations by Country 23
Table 6: Targeted Age Group(s) for Routine Immunization and Most Administered HBV Vaccines by Country in the Global Markets, 2014 24
Table 7: Leading Vaccines for HBV, 2014 27
Table 8: Product Profile - Ambirix 29
Table 9: Immunogenicity Profile - Ambirix 30
Table 10: Safety Profile - Ambirix 31
Table 11: Ambirix SWOT Analysis, 2014 31
Table 12: Global Sales Forecasts ($m) for Ambirix, 2012-2022 32
Table 13: Patient Population(s) Targeted for HBV Vaccination in the Pediatric Market, by Country 52
Table 14: Patient Population(s) Targeted for HBV Vaccination in the Adult Market, by Country 53
Table 15: High-Prescribing Physicians (non-KOLs) Surveyed, by Country 60

1.2 List of Figures

Figure 1: HBV Structure and the Recombinant Vaccine Development Process 14

View This Report »

Get Industry Insights. Simply.

  • Latest reports & slideshows with insights from top research analysts
  • 24 Million searchable statistics with tables, figures & datasets
  • More than 10,000 trusted sources
24/7 Customer Support

Talk to Ahmad

+1 718 618 4302

Purchase Reports From Reputable Market Research Publishers
Cancer Vaccines: Technologies and Global Markets

Cancer Vaccines: Technologies and Global Markets

  • $ 6650
  • Industry report
  • November 2016
  • by BCC Research

This cancer vaccines report by BCC Research explores present and future strategies within the market which includes prophylactic vaccines and therapeutic vaccines. Use this report to: - Analyze the global ...

Veterinary Vaccines Market - Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2016 - 2024

Veterinary Vaccines Market - Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2016 - 2024

  • $ 5795
  • Industry report
  • August 2016
  • by Transparency Market Research

Veterinary vaccines are extensively used in the prevention of life-threatening animal diseases. This report on the global veterinary vaccines market analyzes the current and future prospects of the market. ...

Human Vaccines Market - Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2016 - 2024

Human Vaccines Market - Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2016 - 2024

  • $ 5795
  • Industry report
  • October 2016
  • by Transparency Market Research

Human Vaccines Market: Scope and Methodology This report provides in-depth region wise and country wise analysis of the human vaccines market. Stakeholders of this report include manufacturers of human ...


ref:plp2014

Reportlinker.com © Copyright 2016. All rights reserved.

ReportLinker simplifies how Analysts and Decision Makers get industry data for their business.