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  5. > EpiCast Report: Atrial Fibrillation - Epidemiology Forecast to 2025

EpiCast Report: Atrial Fibrillation - Epidemiology Forecast to 2025

Summary

Atrial fibrillation (AF) is a disorder of the heart’s conduction system. The condition is characterized by an irregular heart rhythm that is either too fast or too slow. During AF, the two upper chambers of the heart (atria) beat out of coordination with the two lower chambers (ventricles) due to disorganized electrical signals. Consequently, the blood doesn’t flow as well as it should from the atria to the ventricles, resulting in poor blood supply to the rest of the body. AF symptoms typically include heart palpitations, chest discomfort, shortness of breath, dizziness, and weakness (CDC, 2015; Mayo Clinic, 2016; NHLBI, 2014). However, individuals with AF may be asymptomatic and not even know that they have the condition until it is identified through an electrocardiogram (ECG) test.

In the 8MM, GlobalData epidemiologists forecast that the diagnosed prevalent cases of AF will increase from 9,487,217 cases in 2015 to 11,536,773 cases in 2025, at an Annual Growth Rate (AGR) of 2.16%. The US will have the highest number of diagnosed prevalent cases of AF among the 8MM throughout the forecast period, while Canada will have the lowest. In the 8MM, permanent AF is forecast to be the predominant subtype of AF. In the US, Germany, Spain, the UK, Japan, and Canada, paroxysmal AF is forecast to be the second most predominant subtype, while persistent AF is the second most common subtype in France and Italy.

Scope

- The Atrial fibrillation (AF) EpiCast Report is an overview of the risk factors, comorbidities, and the global and historical trends for AF in the eight major markets (8MM) (US, France, Germany, Italy, Spain, UK, Japan, and Canada). It includes a 10-year epidemiological forecast for the diagnosed prevalent cases of AF based on country-specific studies published in peer-reviewed journals. The diagnosed prevalent cases of AF are segmented by age (at 5-year intervals, starting at age 40 years), sex, and clinical subtypes (paroxysmal, persistent, and permanent AF) in the 8MM.
- The AF epidemiology report is written and developed by Masters- and PhD-level epidemiologists.
- The EpiCast Report is in-depth, high quality, transparent and market-driven, providing expert analysis of disease trends in the 8MM.

Reasons to Buy

The AF EpiCast report will allow you to -
- Develop business strategies by understanding the trends shaping and driving the global AF market.
- Quantify patient populations in the global AF market to improve product design, pricing, and launch plans.
- Organize sales and marketing efforts by identifying the age groups and sex that present the best opportunities for AF therapeutics in each of the markets covered.

Table Of Contents

EpiCast Report: Atrial Fibrillation - Epidemiology Forecast to 2025
1 Table of Contents
1 Table of Contents 4


2 Epidemiology 6
2.1 Risk Factors and Comorbidities 7
2.2 Global Trends 9
2.3 Forecast Methodology 11
2.3.1 Sources Used 11
2.3.2 Forecast Assumptions and Methods 14
2.3.3 Sources Not Used 21
2.4 Epidemiological Forecast for AF (2015-2025) 22
2.4.1 Diagnosed Prevalent Cases 22
2.5 Discussion 30
2.5.1 Epidemiological Forecast Insight 30
2.5.2 Limitations of the Analysis 31
2.5.3 Strengths of the Analysis 32
3 Appendix 33
3.1 Bibliography 33
3.2 About the Authors 37
3.2.1 Epidemiologist 37
3.2.2 Reviewers 37
3.2.3 Global Director of Therapy Analysis and Epidemiology 38
3.2.4 Global Head of Healthcare 39
3.3 About GlobalData 40
3.4 About EpiCast 40
3.5 Disclaimer 41

1.1 List of Tables
Table 1: Clinical Subtypes of AF 6
Table 2: Risk Factors and Comorbidities for AF 8
Table 3: Prevalence (%) of AF as Reported in Epidemiological Studies 10
Table 4: 8MM, Sources Used to Forecast the Diagnosed Prevalent Cases of AF 12
Table 5: 8MM, Sources Used to Forecast Clinical Subtypes of Diagnosed Prevalent Cases of AF 13
Table 6: 8MM, Sources Not Used in the Epidemiological Analysis of AF 22
Table 7: 8MM, Diagnosed Prevalent Cases of AF, Ages ?40 Years, Both Sexes, N, Selected Years 2015-2025 23
Table 8: 8MM, Age-Specific Diagnosed Prevalent Cases of AF, Both Sexes, N (Row %), 2015 25
Table 9: 8MM, Sex-Specific Diagnosed Prevalent Cases of AF, Ages ?40 Years, N (Row %), 2015 27

1.2 List of Figures
Figure 1: 8MM, Diagnosed Prevalent Cases of AF, Ages ?40 Years, Both Sexes, N, 2015-2025 24
Figure 2: 8MM, Age-Specific Diagnosed Prevalent Cases of AF, Both Sexes, N, 2015 26
Figure 3: 8MM, Sex-Specific Diagnosed Prevalent Cases of AF, Ages ?40 Years, 2015 28
Figure 4: 8MM, Age-Standardized Diagnosed Prevalence of AF, Ages ?40 Years, N, 2015 29
Figure 5: 8MM, Diagnosed Prevalent Cases of AF by Clinical Subtypes, Both Sexes, Ages ?40 Years, 2015 30

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