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Community-Acquired Bacterial Pneumonia - Pipeline Review, H1 2014

  • May 2014
  • -
  • Global Markets Direct
  • -
  • 69 pages

Community-Acquired Bacterial Pneumonia - Pipeline Review, H1 2014

Summary

Global Markets Direct’s, ‘Community-Acquired Bacterial Pneumonia - Pipeline Review, H1 2014’, provides an overview of the Community-Acquired Bacterial Pneumonia’s therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Community-Acquired Bacterial Pneumonia, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Community-Acquired Bacterial Pneumonia and special features on late-stage and discontinued projects.

Global Markets Direct’s report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct’s proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct’s team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope

- The report provides a snapshot of the global therapeutic landscape of Community-Acquired Bacterial Pneumonia
- The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities
- The report reviews key players involved in the therapeutics development for Community-Acquired Bacterial Pneumonia and enlists all their major and minor projects
- The report summarizes all the dormant and discontinued pipeline projects
- A review of the Community-Acquired Bacterial Pneumonia products under development by companies and universities/research institutes based on information derived from company and industry-specific sources
- Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages
- A detailed assessment of monotherapy and combination therapy pipeline projects
- Coverage of the Community-Acquired Bacterial Pneumonia pipeline on the basis of target, MoA, route of administration and molecule type
- Latest news and deals relating related to pipeline products

Reasons to buy

- Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies
- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
- Develop strategic initiatives by understanding the focus areas of leading companies
- Identify and understand important and diverse types of therapeutics under development for Community-Acquired Bacterial Pneumonia
- Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline
- Devise corrective measures for pipeline projects by understanding Community-Acquired Bacterial Pneumonia pipeline depth and focus of Indication therapeutics
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
- Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline

Table Of Contents

Community-Acquired Bacterial Pneumonia - Pipeline Review, H1 2014
Table of Contents
Table of Contents 2
List of Tables 4
List of Figures 5
Introduction 6
Global Markets Direct Report Coverage 6
Community-Acquired Bacterial Pneumonia Overview 7
Therapeutics Development 8
Pipeline Products for Community-Acquired Bacterial Pneumonia - Overview 8
Pipeline Products for Community-Acquired Bacterial Pneumonia - Comparative Analysis 9
Community-Acquired Bacterial Pneumonia - Therapeutics under Development by Companies 10
Community-Acquired Bacterial Pneumonia - Pipeline Products Glance 12
Late Stage Products 12
Clinical Stage Products 13
Early Stage Products 14
Community-Acquired Bacterial Pneumonia - Products under Development by Companies 15
Community-Acquired Bacterial Pneumonia - Companies Involved in Therapeutics Development 16
Melinta Therapeutics, Inc 16
Cubist Pharmaceuticals, Inc. 17
Nabriva Therapeutics AG 18
Tetraphase Pharmaceuticals Inc. 19
Jiangsu Chia-tai Tianqing Pharmaceutical Co., Ltd. 20
Furiex Pharmaceuticals, Inc. 21
Biota Pharmaceuticals, Inc. 22
Community-Acquired Bacterial Pneumonia - Therapeutics Assessment 23
Assessment by Monotherapy Products 23
Assessment by Target 24
Assessment by Mechanism of Action 26
Assessment by Route of Administration 28
Assessment by Molecule Type 30
Drug Profiles 31
solithromycin - Drug Profile 31
Product Description 31
Mechanism of Action 31
RandD Progress 31
faropenem - Drug Profile 33
Product Description 33
Mechanism of Action 33
RandD Progress 33
BC-3781 - Drug Profile 34
Product Description 34
Mechanism of Action 34
RandD Progress 34
radezolid - Drug Profile 35
Product Description 35
Mechanism of Action 35
RandD Progress 35
avarofloxacin hydrochloride - Drug Profile 37
Product Description 37
Mechanism of Action 37
RandD Progress 37
solithromycin - Drug Profile 40
Product Description 40
Mechanism of Action 40
RandD Progress 40
TP-834 - Drug Profile 42
Product Description 42
Mechanism of Action 42
RandD Progress 42
TP-271 - Drug Profile 43
Product Description 43
Mechanism of Action 43
RandD Progress 43
GyrB/ParE Antibiotic - Drug Profile 44
Product Description 44
Mechanism of Action 44
RandD Progress 44
Small Molecules to Inhibit 50S RNA for Infections - Drug Profile 45
Product Description 45
Mechanism of Action 45
RandD Progress 45
Community-Acquired Bacterial Pneumonia - Recent Pipeline Updates 46
Community-Acquired Bacterial Pneumonia - Dormant Projects 58
Community-Acquired Bacterial Pneumonia - Discontinued Products 59
Community-Acquired Bacterial Pneumonia - Product Development Milestones 60
Featured News and Press Releases 60
Mar 13, 2014: TaiGen Biotechnology Receives Marketing Approval from the Taiwan Food and Drug Administration for Taigexyn in Taiwan 60
Feb 20, 2014: Cempra Initiates Solithromycin Pediatric Program 60
Dec 23, 2013: TaiGen Biotechnology Receives Qualified Infectious Disease Product and Fast Track Designations from the U.S. Food and Drug Administration for Nemonoxacin 61
Dec 16, 2013: Cempra Provides Update on Clinical Development of Solithromycin 62
Sep 10, 2013: Cempra to Present Data at ICAAC on Solithromycin's Activity Against a Broad Range of Pathogens Including Four Proposed or Designated by the Food and Drug Administration as Qualified Infectious Disease Pathogens Under the Generating Antibiotic Incentives Now Act 62
Sep 06, 2013: Cempra's Solithromycin Receives Qualified Infectious Disease Product Designation From the U.S. Food and Drug Administration 64
Aug 14, 2013: Theravance Announces Reintroduction of VIBATIV to the U.S. Market 65
Jun 13, 2013: Cempra Provides Guidance On Phase III Clinical Program Required For Regulatory Approval Of Solithromycin For Community-Acquired Bacterial Pneumonia 65
May 28, 2013: Cempra Receives $58m Contract To Develop Antibiotic For Pediatric Use And Biodefense From BARDA 66
May 20, 2013: Cempra Presents Post-Phase II Analysis Of Solithromycin's Efficacy And Safety Results From Patients With Community Acquired Bacterial Pneumonia 67
Appendix 68
Methodology 68
Coverage 68
Secondary Research 68
Primary Research 68
Expert Panel Validation 68
Contact Us 69
Disclaimer 69

List of Tables

Number of Products under Development for Community-Acquired Bacterial Pneumonia, H1 2014 8
Number of Products under Development for Community-Acquired Bacterial Pneumonia - Comparative Analysis, H1 2014 9
Number of Products under Development by Companies, H1 2014 11
Comparative Analysis by Late Stage Development, H1 2014 12
Comparative Analysis by Clinical Stage Development, H1 2014 13
Comparative Analysis by Early Stage Development, H1 2014 14
Products under Development by Companies, H1 2014 15
Community-Acquired Bacterial Pneumonia - Pipeline by Melinta Therapeutics, Inc, H1 2014 16
Community-Acquired Bacterial Pneumonia - Pipeline by Cubist Pharmaceuticals, Inc., H1 2014 17
Community-Acquired Bacterial Pneumonia - Pipeline by Nabriva Therapeutics AG, H1 2014 18
Community-Acquired Bacterial Pneumonia - Pipeline by Tetraphase Pharmaceuticals Inc., H1 2014 19
Community-Acquired Bacterial Pneumonia - Pipeline by Jiangsu Chia-tai Tianqing Pharmaceutical Co., Ltd., H1 2014 20
Community-Acquired Bacterial Pneumonia - Pipeline by Furiex Pharmaceuticals, Inc., H1 2014 21
Community-Acquired Bacterial Pneumonia - Pipeline by Biota Pharmaceuticals, Inc., H1 2014 22
Assessment by Monotherapy Products, H1 2014 23
Number of Products by Stage and Target, H1 2014 25
Number of Products by Stage and Mechanism of Action, H1 2014 27
Number of Products by Stage and Route of Administration, H1 2014 29
Number of Products by Stage and Molecule Type, H1 2014 30
Community-Acquired Bacterial Pneumonia Therapeutics - Recent Pipeline Updates, H1 2014 46
Community-Acquired Bacterial Pneumonia - Dormant Projects, H1 2014 58
Community-Acquired Bacterial Pneumonia - Discontinued Products, H1 2014 59

List of Figures

Number of Products under Development for Community-Acquired Bacterial Pneumonia, H1 2014 8
Number of Products under Development for Community-Acquired Bacterial Pneumonia - Comparative Analysis, H1 2014 9
Number of Products under Development by Companies, H1 2014 10
Comparative Analysis by Clinical Stage Development, H1 2014 13
Assessment by Monotherapy Products, H1 2014 23
Number of Products by Top 10 Target, H1 2014 24
Number of Products by Stage and Top 10 Target, H1 2014 25
Number of Products by Top 10 Mechanism of Action, H1 2014 26
Number of Products by Stage and Top 10 Mechanism of Action, H1 2014 27
Number of Products by Top 10 Route of Administration, H1 2014 28
Number of Products by Stage and Top 10 Route of Administration, H1 2014 29
Number of Products by Stage and Top 10 Molecule Type, H1 2014 30

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