1. Market Research
  2. > Biotechnology
  3. > Genomics Market Trends
  4. > US Next-generation Sequencing Market

US Next-generation Sequencing Market

  • June 2014
  • -
  • Frost & Sullivan
  • -
  • 111 pages

Marketplace Evolves in Preparation for Clinical Sequencing Windfall

The total market, as defined by this study, includes next-generation sequencing instruments and reagents in the United States. Instruments include those that use newer technology than traditional capillary electrophoresis (CE) sequencing, such as sequencing-by-synthesis, sequencing-by-ligation, single-molecule sequencing, and semiconductor sequencing. This research service offers a discussion of the key market drivers and restraints, revenue forecasts, and product types, as well as important trends affecting growth. This analysis also presents key companies to watch, major market dynamics, and strategic recommendations for competitors.


The majority of the quantitative and qualitative information contained in this research service was acquired through primary research conducted with next-generation sequencing instruments and reagents providers. Most consultations were conducted with vice presidents (VPs) of business units, VPs of marketing, product managers, marketing managers, marketing directors, and business development directors from various competitors in the next-generation sequencing market. Industry-specific information obtained include:
-Next-generation sequencing revenue breakdowns by technology segments and regions
-Company revenues, market share estimates, and projected growth rates of various competitors
-Top-level customer, regional, and technology market trend information
-Market drivers, restraints, and challenges Supplementary research was conducted utilizing secondary sources including scientific journals, online media, Frost & Sullivan databases and research services, and publicly available corporate filings. Forecasts are based on the data and analyses regarding industry challenges, market drivers and restraints, and market trends. If specific revenues or market sizes were unavailable, estimates were derived through the consultations with industry experts, augmented by secondary research. Growth trends specific to certain market participants are based on consultations, past growth rates, and technology reviews.

Key Findings

-The total US market for next-generation sequencing (NGS) instruments and reagents generated revenue of $ million in 2013, it is expected to reach $ million in 2018. The market is expected to grow at a CAGR of % from 2013 to 2018.
-The US market accounted for% of global combined NGS instruments and reagents revenue in 2013, while Europe accounted for % and APAC/ROW generated % of market revenue.
-The US NGS instruments market generated $ million in 2013, with a CAGR of % expected to result in a market size of $ million in 2018. The US NGS reagents market totaled $ million in 2013 and is expected to grow at a CAGR of % to $ million in 2018.
-The United States holds the largest NGS instruments installed base of all countries globally, which continues to drive a large reagent pull-through. Adoption of NGS instruments in clinically applied settings, such as reference laboratories, hospitals, and translational research laboratories, will account for more growth over the next 5 years than in traditional labs.
-The United States leads the world in the use of NGS in clinical diagnostics, with NGS-based laboratory developed tests (LDT) already in use, and an expanding pipeline of NGS-based in vitro diagnostic (IVD) tests in the US Food and Drug Administration (FDA) approval process. Between % and % of clinical sequencing is panel-based, while exome sequencing accounts for % to % and whole genomes roughly % to %.
-Market revenues are restrained by the declining instrument costs and reagent costs per genome, yet this trend is also spurring wider accessibility and larger throughput projects. Increasing competition over the next 3 years will further drive down pricing.
-Key vendors in the NGS instrumentation space are Illumina, Life Technologies, Pacific Biosciences and Roche (until the company exits the market in 2015). Emerging competitors expected to enter the NGS instruments market in 2014 or beyond include Oxford Nanopore, Qiagen (Intelligent BioSystems), GnuBIO (acquired by Bio-Rad in 2014), GenapSys, DNA Electronics, NabSys, Genia Technologies, and Noblegen Biosciences.
-Key vendors in the NGS reagents market include Illumina, Life Technologies, Roche, Agilent, Qiagen, and New England Biolabs. This competitor base includes a number of smaller participants, and is expected to expand as companies develop NGS products to take advantage of strong market growth.

The key factors affecting the US NGS market forecast follows:

Application Drivers
oThe price of sequencing falling near the $ genome mark, making large, whole-human genome sequencing projects and population studies feasible
oExpanding use for clinical diagnostics in the form of LDTs, IVD test panels, exome sequencing, and to a lesser extent, whole genome sequencing
oIncreasing use in pharmaceutical applications (i.e., clinical trials, patient stratification, and toxicogenomics)
Technology Trends
oFast pace of technological advancements drives new product launches, making older platforms obsolete and spurring upgrades
oLaunch of clinically focused instruments
oAdvancements in commercially available reagents that increase speed of sample preparation, lower sample volume requirement, and improve project accuracy
oImproved and simplified bioinformatics that enable better data analysis and clinical interpretation
oCreation of very large databases of sequencing and clinical data to improve the clinical utility of genomic information
Macroeconomic Trends
oUS sequestration measures in 2013 negatively affected the academic and government sectors overall, yet the percent of federal funding going to NGS-based projects continues to grow at a much faster pace than funding itself
oGiven the growth potential of NGS and clinical sequencing in particular, this industry is highly advantageous for venture capital funding
Regulatory Trends
oFurther definition of clinical standards and guidelines is needed
oFDA approval of NGS-based IVD tests needs more efficient process

Table Of Contents

US Next-generation Sequencing Market

Key Findings
Scope and Segmentation
Key Questions This Study Will Answer
Market Engineering Measurements
CEO's Perspective
Key Companies to Watch
Executive Summary—3 Big Predictions


Market Background
Market Segmentation
Global Market Perspective
Defining Healthcare Trends in the Future


New Market Opportunities
Merger, Acquisition, and Partnership Assessment


Market Drivers
Market Restraints
Market Impact of Top 10 Trends


Market Engineering Measurements
Forecast Assumptions and Methodology
Total Next-generation Sequencing Market—Revenue Forecast
Total Next-generation Sequencing Market—Revenue Forecast by Product Type
Revenue Forecast by Product Type
Total Next-generation Sequencing Market—Percent Revenue Forecast by Product Type
Revenue Forecast Discussion
Procurement Process


Competitive Environment—Instruments
Instruments Product Analysis—Illumina
Instruments Product Analysis—Life Technologies
Instruments Product Analysis—Roche
Instruments Product Analysis—Pacific Biosciences
NGS Platform Trending—Instruments
Future Competitors—Instruments
NHGRI-funded Sequencing Technology Development
SWOT Analysis—Instruments
Competitive Environment—Reagents
Reagents Product Analysis
Reagents Product Trends


Next-generation Sequencing Instruments Market—Market Engineering Measurements
Next-generation Sequencing Instruments Market—Revenue Forecast
Revenue Forecast Discussion
Next-generation Sequencing Instruments Market—Market Share Analysis


Next-generation Sequencing Reagents Market—Market Engineering Measurements
Next-generation Sequencing Reagents Market—Revenue Forecast
Revenue Forecast Discussion
Next-generation Sequencing Reagents Market—Percent Revenue Forecast by Usage
Next-generation Sequencing Reagents Market—Market Share Analysis


The Last Word—3 Big Predictions
The Last Word—Competitor Base
The Last Word—Creation of Databases to Increase the Clinical Utility of the Genome
The Last Word—Payor and Physician Buy-in
Legal Disclaimer


Drivers Explained
Restraints Explained
Additional Sources of Information
Market Engineering Methodology
Learn More—Next Steps

View This Report »

Get Industry Insights. Simply.

  • Latest reports & slideshows with insights from top research analysts
  • 24 Million searchable statistics with tables, figures & datasets
  • More than 10,000 trusted sources
24/7 Customer Support

Talk to Ahmad

+1 718 618 4302

Purchase Reports From Reputable Market Research Publishers
The Chinese Market for DNA Sequencing

The Chinese Market for DNA Sequencing

  • $ 6650
  • Industry report
  • September 2016
  • by BCC Research

Use this report to: - Learn about recent advances and trends in the Chinese sequencing industry and market. - Analyze the Chinese sequencing market by workflow, including sample preparation products, ...

Next Generation Sequencing (NGS) Global market - Forecast to 2022

Next Generation Sequencing (NGS) Global market - Forecast to 2022

  • $ 4950
  • Industry report
  • November 2016
  • by IQ4I Research & Consultancy Pvt. Ltd

A decade has gone, since the first human genome has been sequenced and sequencing technology has come a long way from the time of introduction as Next generation Sequencing (NGS) has revolutionized the ...

Global Precision Medicine Market

Global Precision Medicine Market

  • $ 4250
  • Industry report
  • December 2016
  • by Mordor Intelligence LLP

The global precision medicine market is expected to reach close to USD 40 billion by the end of 2016, gradually growing at an estimated CAGR of 10.3% by 2021. Precision medicine is an emerging approach ...

Download Unlimited Documents from Trusted Public Sources

The future of the Genome Sequencing Industry

  • January 2017
    2 pages
  • Genome Sequenci...  


View report >

Genome Sequencing Forecast

  • January 2017
    2 pages
  • Genome Sequenci...  

View report >

Genomics Industry in the US

  • January 2017
    4 pages
  • Genomics  

  • United States  

View report >

Genomics Industry

20 days ago

Genomics Industry

21 days ago

Related Market Segments :

Genome Sequencing
Molecular Diagnostic


Reportlinker.com © Copyright 2017. All rights reserved.

ReportLinker simplifies how Analysts and Decision Makers get industry data for their business.