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MediPoint: Spinal Fusion - APAC Analysis and Market Forecasts

Summary

Spinal fusion surgery is a well-established procedure that has been performed since the early 1900s. The procedure has benefited immensely from its long history of use, investments in advancing technologies, and its clinical success in a growing variety of spinal conditions. These traits have led spinal fusion surgery to become one of the most frequently performed surgeries in the US, which is undoubtedly, the largest geographic market for this procedure. Given the global phenomenon of an aging society and the associated increasing incidences of degenerative spinal conditions, the spinal fusion market is expected to remain strong over the forecast period.

This market encompasses a variety of implantable medical technologies, where multiple devices can be utilized in a single procedure. For this research report, the three leading device categories are covered: spinal plating systems, interbody cages, and pedicle screw systems. Additionally, the specific anatomical regions being operated on are covered, including cervical and thoracolumbar. Furthermore, this report analyzes the adoption of these implantables in single-, double-, and triple-level surgeries, creating the most comprehensive and accurate market valuations and coverage. The report analyzes how these surgical trends vary in the major APAC markets, including, Japan, China, and India.

Scope

- An overview of Spinal Fusion, which includes epidemiology, etiology, symptoms, diagnosis, pathology and treatment guidelines.
- Annualized APAC Spinal Fusion market revenue and future forecasts from 2011 to 2013, forecast for 7 years to 2020.
- Investigation of current and future market competition for Spinal Fusion.
- Insightful review of the key industry drivers, restraints and challenges as well as predicted impact of key events.
- Competitor assessment including device approval analysis and device sales forecasts.
- Marketed and pipeline product profiles covering efficiency, safety, clinical study details, device approvals, product positioning and device sales forecast.
- Analysis of unmet needs within the market and opportunities for future players.
- Technology trends evaluation to assess strength of pipeline.
- An overview of all devices in development including clinical study details, design and material selection considerations, efficacy reports, and device approval timelines.
- Company profiles including business description, financial overview and SWOT analysis.
- Coverage of key market players.
- Strategic assessment of the Spinal Fusion sector through market impact analysis, future market scenario and company analysis.
- Direct quotes from Key Opinion Leaders (KOL) as well as doctors

Reasons to buy

- Understand the trends shaping and driving APAC Spinal Fusion market.
- Realize device preferences of physicians who have performed the tests already.
- Access market sizing, forecasts and quantified growth opportunities in APAC Spinal Fusion market through 2018.
- Quantify candidate patient populations to better design product pricing & launch plans.
- Drive revenues, formulate effective sales and marketing strategies and gain in-depth understanding of the competitive landscape.
- Perform benchmarking analysis of growth opportunities against currently marketed products.
- Assess competitiveness of products in market by understanding the strengths and weaknesses of current competition.
- Take a comprehensive look at the market’s device pipeline and identify promising, paradigm-shifting products.
- Create an effective counter-strategy to gain a competitive advantage against those currently in the market.
- Organize your sales and marketing efforts by identifying the market categories and segments that present the best opportunities for growth.
- What’s the next big thing in APAC Spinal Fusion market landscape? Identify, understand and capitalize.

Table Of Contents

MediPoint: Spinal Fusion - APAC Analysis and Market Forecasts
1 Table of Contents

2 Introduction 13
2.1 Overview 13
2.2 Catalyst 13
3 Industry Overview 15
3.1 Indications 15
3.2 Types of Devices 17
3.2.1 Spinal Plating Systems 17
3.2.2 Interbody Cages 18
3.2.3 Pedicle Screw Systems 19
3.3 Procedure Trends 20
3.4 Market Access 25
3.4.1 Regulation 25
3.4.2 Adoption 28
3.4.3 Reimbursement Trends 29
4 Market Dynamics: Mergers, Acquisitions and Key Partnerships 33
4.1 Overview 33
4.1.1 Amedica Corporation Acquires US Spine 34
4.1.2 Alphatec Spine Acquires Scient'x Group 34
4.1.3 Biomet Acquires Lanx, Inc. 34
4.1.4 Globus Medical Acquires Facet Solutions 34
4.1.5 Integra LifeSciences Holdings Corporation Acquires SeaSpine, Inc. 35
4.1.6 Medtronic Acquires Advanced Medical Technologies and China's Kanghui 35
4.1.7 Nuvasive Acquires ANC 35
4.1.8 TranS1 Inc. Acquires Baxano Inc. 35
4.2 Economic Impact 36
5 Unmet Needs 39
5.1 Improved Reimbursement Coverage for Minimally Invasive Surgical Procedures 39
5.2 Lack of Definitive Methods to Determine Fusion Performance 40
5.3 Technological Developments in the Use of Long Fusions 40
5.4 Research and Development into Fusion Enhancers 42
5.5 Improve Osseointegration of Bone and Screw Interface 43
6 Market Opportunity Analysis 45
6.1 Develop Signature Minimally Invasive Technique 45
6.2 Market Minimally Invasive Training Opportunities to Fellowship Programs 46
6.3 Increased Collaboration of Medical Device Implants and Biologics 47
6.4 Develop a Device that Provides Real-Time Fusion Updates 48
6.5 Increased Customization of Spinal Implants to Patient Anatomy 48
7 Market Drivers 50
7.1 Aging Patient Populations 50
7.2 Growth in the Spinal Stenosis Indication 52
7.3 Gold Standard for Treating Spinal Instability and Degenerative Conditions 54
7.4 Treatment for a Variety of Indications 54
7.5 Preference for Minimally Invasive Techniques 55
7.6 Advances in Navigation Technology 57
8 Market Barriers 58
8.1 Incidence of Adjacent Segment Disease 58
8.2 Performance of Non-Fusion Technologies 58
8.3 Increased Scrutiny over Spinal Fusion's Necessity in the US 60
8.4 Restricted Reimbursement from Private Payers 61
8.5 Performance in Treating Axial Back Pain 62
9 Pipeline Assessment 63
10 Clinical Trial Analysis 66
11 Current and Future Players 68
11.1 Overview 68
11.2 Trends in Corporate Strategy 68
11.3 Company Profiles 68
11.3.1 Aesculap 68
11.3.2 Alphatec Spine 71
11.3.3 Amedica Corporation 74
11.3.4 Medtronic Spinal and Biologics 76
11.3.5 DePuy Spine 79
11.3.6 Globus Medical 81
11.3.7 K2M 84
11.3.8 Biomet 86
11.3.9 Stryker 89
11.3.10 Zimmer 92
11.3.11 Nuvasive 96
11.3.12 Orthofix 99
11.3.13 Integra LifeSciences 102
12 Market Outlook 106
12.1 By Geography 107
12.1.1 Japan 107
12.1.2 China 108
12.1.3 India 110
13 Appendix 112
13.1 Bibliography 112
13.2 Abbreviations 122
13.3 Report Methodology 123
13.3.1 Overview 123
13.3.2 Coverage 123
13.3.3 Primary Research 123
13.3.4 Secondary Research 124
13.3.5 Forecasting Methodology 125
13.4 Key Opinion Leaders Included in this Study 126
13.5 About the Authors 127
13.5.1 Joseph A. Gregory, Analyst, Surgical Devices 127
13.5.2 Derek Archila, MBA, Director of Research and Analysis, Medical Devices 127
13.6 Global Head of Healthcare 128
13.6.1 Bonnie Bain, Ph.D., Global Head of Healthcare 128
13.7 About MediPoint 129
13.8 About GlobalData 129
13.9 Disclaimer 129

1.1 List of Tables

Table 1: Indications for Lumbar Spinal Fusion 16
Table 2: Adoption of Spinal Fusion and Spinal Non-Fusion, APAC, 2013 and 2020 20
Table 3: Spinal Plating Systems CAGR, APAC, Based on 2013 and 2020 Procedure Volumes 21
Table 4: Interbody Cages CAGR, APAC, Based on 2013 and 2020 Procedure Volumes 23
Table 5: Pedicle Screw Systems CAGR, APAC, Based on 2013 and 2020 Procedure Volumes 24
Table 6: Adoption of Spinal Implants for Cervical Fusion Procedures, APAC, 2013 28
Table 7: Adoption of Spinal Implants for Thoracolumbar Fusion Procedures, APAC, 2013 29
Table 8: Mergers and Acquisitions, 2010-2014 33
Table 9: Population Aged 60 Years Old or Over, 1950-2050 (in millions) (percentage in older ages) 50
Table 10: Overall Perceived Advantages of Minimally Invasive Surgery Techniques, 2007 56
Table 11: Overall Perceived Limitations of Minimally Invasive Surgery Techniques, 2007 56
Table 12: Company Portfolio - Aesculap 69
Table 13: Product Portfolio - Aesculap 70
Table 14: Company Portfolio - Alphatec Spine 72
Table 15: Product Portfolio - Alphatec Spine 73
Table 16: Company Portfolio - Amedica 75
Table 17: Product Portfolio - Amedica 76
Table 18: Company Portfolio - Medtronic Spinal and Biologics 77
Table 19: Product Portfolio - Medtronic Spinal and Biologics 78
Table 20: Company Portfolio - DePuy Spine 80
Table 21: Product Portfolio - DePuy Spine 80
Table 22: Company Portfolio - Globus Medical 82
Table 23: Product Portfolio - Globus Medical 83
Table 24: Company Portfolio - K2M 85
Table 25: Product Portfolio - K2M 85
Table 26: Company Portfolio - Biomet 87
Table 27: Product Portfolio - Biomet 88
Table 28: Company Portfolio - Stryker 90
Table 29: Product Portfolio - Stryker 91
Table 30: Company Portfolio - Zimmer 94
Table 31: Product Portfolio - Zimmer 95
Table 32: Company Portfolio - Nuvasive 97
Table 33: Product Portfolio - Nuvasive 98
Table 34: Company Portfolio - Orthofix 100
Table 35: Product Portfolio - Orthofix 101
Table 36: Company Portfolio - Integra LifeSciences 103
Table 37: Product Portfolio - Integra LifeSciences 104
Table 38: Spinal Surgery, APAC Company Market Share, 2012 106
Table 39: Japan Spinal Fusion Sales ($m) Forecast, 2011-2020 107
Table 40: China Spinal Fusion Sales ($m) Forecast, 2011-2020 109
Table 41: India Spinal Fusion Sales ($m) Forecast, 2011-2020 110

1.2 List of Figures

Figure 1: Spinal Plating Procedure Volumes, APAC, 2011-2020 22
Figure 2: Interbody Cages Procedure Volumes, APAC, 2011-2020 23
Figure 3: Pedicle Screw Systems Procedure Volumes, APAC, 2011-2020 25
Figure 4: Spinal Fusion Procedure Volumes, US, 2002-2011 37
Figure 5: Spinal Surgery, APAC Company Market Share, 2012 106
Figure 6: Japan Spinal Fusion Sales ($m) Forecast, 2011-2020 108
Figure 7: China Spinal Fusion Sales ($m) Forecast, 2011-2020 109
Figure 8: India Spinal Fusion Sales ($m) Forecast, 2011-2020 111

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