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Drug Discovery Technologies - A Global Market Overview

  • August 2014
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  • Industry Experts
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  • 248 pages

The development of new drugs for treating difficult diseases, such as cancer requires extensive expenditure, in addition to consuming a lot of time. The first step in designing a new drug involves the utilizing high-throughput screening of large chemical libraries for identifying compounds that can provide the requisite therapeutic effect. The capability of visualizing biological activity at the cellular level has constituted a strategic component in drug discovery, and adding automation and high-volume screening methods has enabled in testing compounds in large numbers. The field of pharmaceutical research is being provided considerable impetus through the combination of imaging and screening.

Worldwide market for drug discovery technologies explored in this study includes Bioanalytical Assays, Bioinformatics, Cell Based Assays, Genomic Technologies, High Throughput Screening, Proteomic Technologies and Others comprising Epigenetics, Metabolomics, Combinatorial Chemistry, Synthetic Biology, Systems Biology and Nanotechnology.

The global market value for the above mentioned technologies is analyzed in USD. High Throughput Screening accounts for a lion’s share in global drug discovery technologies market with an expected share of about 30% in 2015 valued at $18 billion followed by Bioanalytical Assays or instruments by about $14 billion.

This 248 pages global market report includes 28 charts (includes a data table and graphical representation for each chart), supported with meaningful and easy to understand graphical presentation, of market numbers. This report profiles 56 key global players and 67 major players across the United States – 41; Europe – 16; Asia-Pacific – 7; and Rest of World - 3. The research also provides the listing of the companies that are engaged in technology, contract research services and providers of discovery technologies. The global list of companies covers addresses, contact numbers and the website addresses of 186 companies.

Table Of Contents

Drug Discovery Technologies - A Global Market Overview
TABLE OF CONTENTS:

PART A: GLOBAL MARKET PERSPECTIVE

1. INTRODUCTION
1.1 Product Outline
1.1.1 Backdrop
1.1.2 What Is Drug Discovery?
1.1.2.1 Screening and Design
1.1.3 Omics in Drug Discovery and Development
1.1.4 Process of Discovering Improved Drugs Provided by a Technological Revolution
1.1.5 Drug Discovery Technologies
1.1.5.1 Bioanalytical Assays
1.1.5.1.1 Bio-Analytical Techniques
1.1.5.1.2 Sample Extraction
1.1.5.2 Bioinformatics
1.1.5.2.1 Computer-Aided Drug Design
1.1.5.3 Cell Based Assays
1.1.5.3.1 Cell-Based Assays in High-Throughput Screening for Drug Discovery
1.1.5.4 Genomic Technologies
1.1.5.4.1 Drug Discovery
1.1.5.4.2 Clinical Medicine
1.1.5.4.3 New Antibiotics
1.1.5.5 High Throughput Screening
1.1.5.5.1 High Throughput Screening in Drug Discovery
1.1.5.6 Proteomic Technologies
1.1.5.6.1 A Proteomics Approach to Biomarker Discovery and Drug Development
1.1.5.7 Other Technologies
1.1.5.7.1 Epigenetics
1.1.5.7.1.1 Epigenetics and Cancer Treatment
1.1.5.7.2 Metabolomics
1.1.5.7.2.1 Target Identification
1.1.5.7.2.2 Target Validation
1.1.5.7.2.3 Lead Optimization
1.1.5.7.2.4 Mode of Action
1.1.5.7.2.5 Preclinical Studies
1.1.5.7.2.6 Clinical Studies
1.1.5.7.2.7 Post-Approval Studies
1.1.5.7.2.8 Diagnostics
1.1.5.7.3 Combinatorial Chemistry
1.1.5.7.3.1 Chemical Encoding
1.1.5.7.3.2 Positional Encoding
1.1.5.7.3.3 Electronic Encoding
1.1.5.7.4 Synthetic Biology
1.1.5.7.5 Systems Biology
1.1.5.7.5.1 Computer Modelling
1.1.5.7.6 Nanotechnology

2. KEY MARKET TRENDS
2.1 Drug Discovery Gets Faster, Smarter and Cheaper
2.2 Drug Discovery Being Enabled through Halogen Bonds
2.3 Drug Discovery Bolstered by New Use for Stem Cells in Targeting ALS
2.4 Personalized Medicine: Advantage Patients, Disadvantage Drug Companies
2.5 Identification of Diagnostic and Therapeutic Targets Better Enabled by Combining Plasma Screening and Genetic Screening
2.6 Source of New Drug Category from Trapping Malaria Parasites inside Host Blood Cell
2.7 Fighting Malaria Drug Resistance through an Innovative Method
2.8 Drug Screening in 3D Using High-Throughput Chip
2.9 Drug Discovery Expedited through 3D Protein Mapping
2.10 Drug Discovery and Automated Cell Staining
2.11 Drug Discovery and Development for Complex Disease Targets to be Alleviated through a Computer Program

3. RECENT PATENTS IN DRUG DISCOVERY LANDSCAPE
USPTO Issues '979 Patent for Biohaven's Glutamate Modulating Agents to Treat GAD
Patents Issued for Suven's New Chemical Entities to treat Neurodegenerative Disorders
Japan Patent Office Approves Patent for C4XD's Technology
Additional Patents Issued on MorphoSys' Ylanthia in the US and in China
Sareum Receives a Patent for its Kinase Inhibitors in Japan
USPTO Grants Patent for Prima BioMed's CVac
Japan Patent Office Decides to Issue Patent for Marina's SMARTICLES® Nucleic Acid Delivery Technology
USPTO Grants a Patent in Regulus' Sarnow Patent Estate on microRNA Therapies to Treat HCV
USPTO Grants Patent for Kadimastem's Cell Technology
USPTO Grants a Novel Patent in Alnylam's McSwiggen Patent Estate
Suven Receives Patent Approval in the US for its Major Depressive Disorder Drug
Notice of Allowance for Canadian Patent Granted to VistaGen
Issue of Patent on Broad Institute's New Gene-Editing Method
US Patent Office Grants Patent for HUB's Method of Growing Organoids
Dyadic Granted US Patent for High Throughput Screening
US Patent Granted to Theranostics Health
Reveleris Flash Chromatography System Receives Patent from the Australian Patent Office
Sareum Receives Patent for one of its CHK1 Cancer Programme-related Inventions in the US
Lpath's iSONEP Receives Patent from USPTO
KeyGene Obtains Patent for High Throughput Screening in the US
BioInvent's F.I.R.S.T. Drug Discovery Technology Gets Patent in the US
Plasticell Receives Additional Patents for its CombiCult® Cell Culture Technology in the US, Europe, Australia and Singapore
EntomoPharm Receives Patent for its BBB Insect Model in Europe
Summit Gets Patent for Utrophin Modulator SMT C1100 in the US
USPTO Grants Patent to OncoMed for Methods of Treating Cancer with its Antibody Vantictumab
Novel Component of Phylomer® Peptide Platform Patented by Phylogica for Advanced Cell-Penetrating Drug Discovery
COTI Receives Two Newly Granted Patents for its Lead Oncology Asset in the US

4. KEY GLOBAL PLAYERS
4-Antibody AG
Abbott Laboratories
Accelrys, Inc.
Affymetrix Inc.
Agilent Technologies Inc.
Asahi Kasei Pharma Corporation
Astrazeneca Plc
Aviva Biosciences Corp.
Bayer Healthcare AG
BD Biosciences
Beckman Coulter Inc.
Biacore International AB
Bioanalytical Systems, Inc.
Bio-Rad Laboratories, Inc.
Boehringer Ingelheim GmbH
Bristol-Myers Squibb Company
Caliper Life Sciences, Inc.
Caprion Proteomics, Inc.
Celera Corporation
Celgene Corporation
Charles River Laboratories International, Inc.
Compugen Ltd.
Decode Genetics, Inc.
EMD Millipore Corporation
Evotec AG
GE Healthcare Ltd.
Genedata AG
Hitgen Ltd
Hudson Robotics, Inc.
Illumina Inc.
Incyte Corporation
Isis Pharmaceuticals, Inc.
Kyowa Hakko Kirin Co., Ltd.
Luminex Corporation
Maxcyte, Inc
Merck and Co., Inc.
Millennium Pharmaceuticals, Inc.
Molecular Devices, LLC
Molecular Discovery Ltd.
Molecular Discovery Systems Pty., Ltd.
New England Biolabs, Inc.
Novartis AG
Osiris Therapeutics Inc.
Perkinelmer, Inc.
Promega Corporation
Qiagen N.V.
Quantum Pharmaceuticals
Roche Holding AG
Shimadzu Corporation
Sigma-Aldrich Corporation
Sri Biosciences
Tecan Group Ltd.
The National Center for Drug Screening
Thermo Fisher Scientific Inc.
Viva Biotech Ltd
Waters Corp.

5. KEY BUSINESS TRENDS
Evotec Established Alliance with Eternygen on New Small Molecule Inhibitors Development
MRC Technology Partnered With Daiichi Sankyo to Discover New Drug Targets
Evotec, Debiopharm Groupâ„¢ to Discover New Drugs to treat Cancer
Daiichi Sankyo Forms Alliance with UCSF on New Cures Development to Treat Neurodegenerative Diseases
Debut of a Synergetic Drug Discovery Project for 2014 by Daiichi Sankyo
Analgesic Drug Discovery and Development Collaboration Formed by Convergence and Evotec
MIT SBC, Pfizer Enter into a Three-Year Drug Discovery Research Alliance
Abide, Celgene Partners to Discover and Develop Novel Drugs to Treat Inflammation and Immunological Disorders
Novel Genetic Platform Having the Ability to Yield Natural Microbial Genomes
Johnson and Johnson Innovation Signs Novel Agreements with NEOMED and MaRS Innovation
Boehringer Ingelheim and Circuit Therapeutics Form Drug Discovery Research Pact for Three Years
Life Technologies and NCATS form RNAi Research Alliance to Enhance Novel Therapeutics Discovery
Novel Core Unit of USTAR and U of U Eases Pharmacological Therapeutic Development
JHL Biotech Inks Strategic Collaboration with Selexis to Develop Biologic Drugs
Bayer Offer Funding to the SGC for Expediting Drug Research
HitGen, the University of Manchester's Cancer Research UK Manchester Institute Drug Discovery Group and Cancer Research Technology Form Drug Discovery Pact
BioFocus, Boehringer Ingelheim Enter Into Drug Discovery Pact
Evotec Establishes Drug Discovery Alliance with Johnson and Johnson Innovation on AD Targets
Release of GE Healthcare Life Sciences' Novel Xuriâ„¢ Technology Family
4SC Discovery, CRELUX and AiCuris Form Drug Discovery Pact
Novel SLAP Technology for Drug Discovery Advancements
Inauguration of GE Healthcare Life Sciences Technology Laboratory at the UK's First Open Innovation Bioscience Campus
Debut of an "Open Innovation" Research Alliance by AstraZeneca and Taiwan's NRPB to Accelerate Drug Discovery
Asahi Kasei Pharma and Vernalis plc Collaborate to Discover Drugs for Autoimmune Diseases
Launch of Thermo Fisher Scientific's Novel Innovations at BioProcess International Conference and Exhibition
Adimab Establishes Alliance with Celgene on Multi-target Discovery
Eurofins Scientific, GE Healthcare Enter Pact on Drug Discovery Services
Debut of Boehringer Ingelheim and Polyphor into the Next Research Stage of their Alliance
Commercial Release of Agilent's RapidFire 365 High-Throughput Mass Spectrometry System
Zalicus Plans to Advance Clinical Development of Z944
Debut of Kinexus' DrugKiNET KnowledgeBase
Evotec Establishes Alliance with Harvard University to Develop Novel Antibacterial Agents
UCSF Turns to be the First Partner of Pfizer's CTI in Both Small-Molecule and Biologics Discovery
In-House Development of Various Novel Antiviral Drugs from Achillion
Launch of Thermo Fisher Scientific's Drug Discovery and Biopharma Production Innovations
Sareum Partners with SRI International for Advancing the Clinical Development of Tyrosine Kinase 2 Small Molecule Drug Discovery Program
Launch of Hudson Robotics' High Efficiency Screening, an Advanced Drug Discovery Technology
Accelrys Insight and Accelrys Insight for Excel Drug Discovery Softwares from Accelrys, Inc
Renewal of Evotec and Genentech's Drug Discovery Collaboration
Alchemia, AstraZeneca Form Multi-Target Drug Discovery Pact
RaQualia Establishes Research Alliance with Interprotein to Discover PPI Inhibitor
Collaborative Effort of Evotec and Ono Yields Novel Compounds for Preclinical Development
Galapagos Takeover Cangenix Assets
EMD Millipore's Novel Genomic Biomarker Services
Marketing of an Advanced Metabolite-Identification Platform by Agilent and Molecular Discovery
QuantiGene® ViewRNA Assay Platform-based Novel Cancer Biomarker Tests Co-developed by Affymetrix and MGH
Numerate and Merck Partnered to Discover Drug Leads for Cardiovascular Disease Target
Evotec Partners with IR Pharma to Offer Drug Discovery Solutions in the Area of Respiratory Diseases

6. GLOBAL MARKET OVERVIEW
6.1. Global Market Overview by Technology
6.1.1 Drug Discovery Technology Overview by Global Region
6.1.1.1 Bioanalytical Assays
6.1.1.2 Bioinformatics
6.1.1.3 Cell Based Assays
6.1.1.4 Genomic Technologies
6.1.1.5 High Throughput Screening
6.1.1.6 Proteomic Technologies
6.1.1.7 Other Drug Discovery Technologies

PART B: REGIONAL MARKET PERSPECTIVE

REGIONAL MARKET OVERVIEW

1. THE UNITED STATES
1.1 United States Market Overview by Technology
1.2 Major Market Players
Abbott Laboratories
Accelrys, Inc.
Affymetrix Inc.
Agenus Inc.
Agilent Technologies Inc.
Albany Molecular Research, Inc.
Arqule Inc.
Aviva Biosciences Corp.
BD Biosciences
Beckman Coulter Inc.
Bioanalytical Systems, Inc.
Bio-Rad Laboratories, Inc.
Biovision, Inc.
Bristol-Myers Squibb Company
Bruker Corporation
Caliper Life Sciences, Inc.
Capital Genomix, Inc.
Celera Corporation
Celgene Corporation
Charles River Laboratories International, Inc.
Discoverx Corporation
Discovery Genomics, Inc.
EMD Millipore Corporation
Hudson Robotics, Inc.
Illumina Inc.
Incyte Corporation
Isis Pharmaceuticals, Inc.
Life Technologies Corporation
Luminex Corporation
Maxcyte, Inc
Merck and Co., Inc.
Millennium Pharmaceuticals, Inc.
Molecular Devices, LLC
New England Biolabs, Inc.
Osiris Therapeutics Inc.
Perkinelmer, Inc.
Promega Corporation
Sigma-Aldrich Corporation
SRI Biosciences
Thermo Fisher Scientific Inc.
Waters Corp.

2. EUROPE
2.1 European Market Overview by Technology
2.2 Major Market Players
4-Antibody AG (Switzerland)
Astrazeneca Plc (United Kingdom)
Bayer Healthcare AG (Germany)
Biacore International AB (Sweden)
Biofocus Dpi, Ltd (United Kingdom)
Boehringer Ingelheim GmbH (Germany)
Decode Genetics, Inc. (Iceland)
Evotec AG (Germany)
GE Healthcare Ltd. (United Kingdom)
Genedata AG (Switzerland)
Molecular Discovery Ltd. (Italy)
Novartis AG (Switzerland)
Qiagen N.V. (The Netherlands)
Quantum Pharmaceuticals (Russia)
Roche Holding AG (Switzerland)
Tecan Group Ltd. (Switzerland)

3. ASIA-PACIFIC
3.1 Asia-Pacific Market Overview by Technology
3.2 Major Market Players
Asahi Kasei Pharma Corporation (Japan)
Hitgen Ltd (China)
Kyowa Hakko Kirin Co., Ltd. (Japan)
Molecular Discovery Systems Pty., Ltd. (Australia)
Shimadzu Corporation (Japan)
The National Center for Drug Screening (China)
Viva Biotech Ltd (China)

4. REST OF WORLD
4.1 Rest of World Market Overview by Technology
4.2 Major Market Players
Caprion Proteomics, Inc. (Canada)
Compugen Ltd. (Israel)
Pluristem Therapeutics Inc. (Israel)

PART C: GUIDE TO THE INDUSTRY
1. NORTH AMERICA
1.1 Canada
1.2 United States
2. EUROPE
2.1 Belgium
2.2 Denmark
2.3 France
2.4 Germany
2.5 Iceland
2.6 Ireland
2.7 Italy
2.8 Russia
2.9 Sweden
2.10 Switzerland
2.11 The Netherlands
2.12 The United Kingdom
3. ASIA-PACIFIC
3.1 Australia
3.2 China
3.3 India
3.4 Japan
3.5 Singapore
3.6 Taiwan
4. REST OF WORLD
4.1 Israel

PART D: ANNEXURE
1. RESEARCH METHOLOGY
2. FEEDBACK

Charts and Graphs

PART A: GLOBAL MARKET PERSPECTIVE
Chart 1: Global Drug Discovery Technologies Market Analysis (2010-2020) in USD Million
Chart 2: Global Drug Discovery Technologies Market Analysis (2010-2020) by Discovery Technology - Bioanalytical Assays, Bioinformatics, Cell Based Assays, Genomic Technologies, High Throughput Screening, Proteomic Technologies and Other Technologies in USD Million
Chart 3: Glance at 2010, 2015 and 2020 Global Drug Discovery Technologies Market Share (%) by Discovery Technology - Bioanalytical Assays, Bioinformatics, Cell Based Assays, Genomic Technologies, High Throughput Screening, Proteomic Technologies and Other Technologies
Chart 4: Global Market for Bioanalytical Assays in Drug Discovery (2010-2020) by Geographic Region - United States, Europe, Asia-Pacific and Rest of World in USD Million
Chart 5: Glance at 2010, 2015 and 2020 Global Market Share of Bioanalytical Assays in Drug Discovery (%) by Geographic Region - United States, Europe, Asia-Pacific and Rest of World
Chart 6: Global Market for Bioinformatics in Drug Discovery (2010-2020) by Geographic Region - United States, Europe, Asia-Pacific and Rest of World in USD Million
Chart 7: Glance at 2010, 2015 and 2020 Global Market Share of Bioinformatics in Drug Discovery (%) by Geographic Region - United States, Europe, Asia-Pacific and Rest of World
Chart 8: Global Market for Cell Based Assays in Drug Discovery (2010-2020) by Geographic Region - United States, Europe, Asia-Pacific and Rest of World in USD Million
Chart 9: Glance at 2010, 2015 and 2020 Global Market Share of Cell Based Assays in Drug Discovery (%) by Geographic Region - United States, Europe, Asia-Pacific and Rest of World
Chart 10: Global Market for Genomic Technologies in Drug Discovery (2010-2020) by Geographic Region - United States, Europe, Asia-Pacific and Rest of World in USD Million
Chart 11: Glance at 2010, 2015 and 2020 Global Market Share of Genomic Technologies in Drug Discovery (%) by Geographic Region - United States, Europe, Asia-Pacific and Rest of World
Chart 12: Global Market for High Throughput Screening in Drug Discovery (2010-2020) by Geographic Region - United States, Europe, Asia-Pacific and Rest of World in USD Million
Chart 13: Glance at 2010, 2015 and 2020 Global Market Share of High Throughput Screening in Drug Discovery (%) by Geographic Region - United States, Europe, Asia-Pacific and Rest of World
Chart 14: Global Market for Proteomic Technologies in Drug Discovery (2010-2020) by Geographic Region - United States, Europe, Asia-Pacific and Rest of World in USD Million
Chart 15: Glance at 2010, 2015 and 2020 Global Market Share of Proteomic Technologies in Drug Discovery (%) by Geographic Region - United States, Europe, Asia-Pacific and Rest of World
Chart 16: Global Market for Other Drug Discovery Technologies in Drug Discovery (2010-2020) by Geographic Region - United States, Europe, Asia-Pacific and Rest of World in USD Million
Chart 17: Glance at 2010, 2015 and 2020 Global Market Share of Other Drug Discovery Technologies in Drug Discovery (%) by Geographic Region - United States, Europe, Asia-Pacific and Rest of World

PART B: REGIONAL MARKET PERSPECTIVE
Chart 18: The Projection of Largest Regions in terms of Market Growth for Drug Discovery Technologies by Geography - Asia-Pacific, Europe and United States
Chart 19: Global Drug Discovery Technologies Market Analysis (2010-2020) by Geographic Region - United States, Europe, Asia-Pacific and Rest of World in USD Million
Chart 20: Glance at 2010, 2015 and 2020 Global Drug Discovery Technologies Market Share (%) by Geographic Region - United States, Europe, Asia-Pacific and Rest of World

THE UNITED STATES
Chart 21: United States Drug Discovery Technologies Market Analysis (2010-2020) by Discovery Technology - Bioanalytical Assays, Bioinformatics, Cell Based Assays, Genomic Technologies, High Throughput Screening, Proteomic Technologies and Other Technologies in USD Million
Chart 22: Glance at 2010, 2015 and 2020 United States Drug Discovery Technologies Market Share (%) by Discovery Technology - Bioanalytical Assays, Bioinformatics, Cell Based Assays, Genomic Technologies, High Throughput Screening, Proteomic Technologies and Other Technologies

EUROPE
Chart 23: European Drug Discovery Technologies Market Analysis (2010-2020) by Discovery Technology - Bioanalytical Assays, Bioinformatics, Cell Based Assays, Genomic Technologies, High Throughput Screening, Proteomic Technologies and Other Technologies in USD Million
Chart 24: Glance at 2010, 2015 and 2020 European Drug Discovery Technologies Market Share (%) by Discovery Technology - Bioanalytical Assays, Bioinformatics, Cell Based Assays, Genomic Technologies, High Throughput Screening, Proteomic Technologies and Other Technologies

ASIA-PACIFIC
Chart 25: Asia-Pacific Drug Discovery Technologies Market Analysis (2010-2020) by Discovery Technology - Bioanalytical Assays, Bioinformatics, Cell Based Assays, Genomic Technologies, High Throughput Screening, Proteomic Technologies and Other Technologies in USD Million
Chart 26: Glance at 2010, 2015 and 2020 Asia-Pacific Drug Discovery Technologies Market Share (%) by Discovery Technology - Bioanalytical Assays, Bioinformatics, Cell Based Assays, Genomic Technologies, High Throughput Screening, Proteomic Technologies and Other Technologies

REST OF WORLD
Chart 27: Rest of World Drug Discovery Technologies Market Analysis (2010-2020) by Discovery Technology - Bioanalytical Assays, Bioinformatics, Cell Based Assays, Genomic Technologies, High Throughput Screening, Proteomic Technologies and Other Technologies in USD Million
Chart 28: Glance at 2010, 2015 and 2020 Rest of World Drug Discovery Technologies Market Share (%) by Discovery Technology - Bioanalytical Assays, Bioinformatics, Cell Based Assays, Genomic Technologies, High Throughput Screening, Proteomic Technologies and Other Technologies

Table 1: Prominent Technologies used for Bioanalytical Research
Table 2: Prominent Types of Cell Based Assays used in High Throughput Screening

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