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Therapeutic Biological Drugs to 2020

  • October 2014
  • -
  • Greystone Research Associates

In recent years, the number of biological drugs in development and reaching the marketplace has increased significantly. The clinical application of these drugs is sometimes limited by a lack of desirable attributes for adequate absorption or distribution. So it’s critical to formulate these drugs into safe, stable and efficacious delivery systems. Because these drugs face formidable enzymatic and penetration barriers when administered orally, peptide and protein drugs continue to be developed almost exclusively for parenteral administration. The growth of biological drug products is having a significant effect on the way drugs and devices are developed. Cooperation between device designers and drug developers is occurring much earlier in the drug development cycle, allowing device designs in many cases to be tailored to the bioavailability targets and pharmacokinetic profiles of specific drug therapies.

What you Will Learn
- What biological drugs are currently marketed, how are they positioned in the market, what are the device specifics, and who markets them?
- Who are the important biological drug suppliers, their manufacturing infrastructure and locations, their capabilities?
- What are the major factors driving biological drug demand?
- How important are drug developer-ecosystem partner relationships and what are the key alliances in the industry?
- What are the essential design factors, material selection issues, technologies and market development issues for biological drug products?
- How are biological drugs aligned with various drug classes and therapeutic markets?
- What are the significant economic, technology, and regulatory factors affecting biological drugs?

Table Of Contents

Therapeutic Biological Drugs to 2020
Summary of Contents
Executive Summary

Biological Therapeutics Market Dynamics

The Biological Therapeutics Market Space
Clinical Trials and Drug Approvals
The Competitive Landscape
Demographics, Managed Care and Growth
Risks and Opportunities

Formulating Biological Drugs

Formulation Strategies
Stability
Half?Life and Therapeutic Protocols
Immunogenicity
Biological Formulation Technologies
Post?translational Modification
Encapsulation Technologies
Sustained Release Formulations
Conjugation
Lyophilization
Dosing Frequency
Treatment Compliance

Protein Drugs: Drug Analysis and Competitive Positioning

Antibodies
Enzymes
Growth Factors
Hematopoietics
Hormones
Immune Modulators
Other Protein Therapy Classes

Biological Drug Therapeutic Markets - Market Data and Forecasts

Antivirals
Asthma
Autoimmunity
Cardiology
Hematopoietics
Hepatitis
Immunotherapeutics
Metabolic Diseases
Multiple Sclerosis
Osteoporosis
Oncology
Ophthalmology
Orphan Diseases

Company Profiles

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