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Complete 2013-14 Induced Pluripotent Stem Cell Industry Report

  • February 2014
  • -
  • BioInformant Worldwide, L.L.C.
  • -
  • 127 pages

EXECUTIVE SUMMARY
Stem cell research and experimentation has been in process for well over five decades, as stem cells have the unique ability to divide and replicate repeatedly. In addition, their “unspecialized” nature allows them to differentiate into a wide variety of specialized cell types. The possibilities arising from these characteristics have caused great commercial interest, with potential applications ranging from the use of stem cells in reversal or treatment of disease, to targeted cell therapy, tissue regeneration, pharmacological testing on cell-specific tissues, and more. Diseases such as Huntington’s Chorea, Parkinson’s Disease, and spinal cord injuries are examples of clinical applications in which stem cells could offer benefits in halting or even reversing damage.

Traditionally, scientists have worked with both embryonic and adult stem cells as research tools. While the appeal of embryonic cells has been their ability to differentiate into any type of cell, there has been significant ethical, moral and spiritual controversy surrounding their use for research purposes. Although some adult stem cells do have differentiation capacity, it is often limited in nature, which creates narrow options for use. Thus, induced pluripotent stem cells represent a promising combination of adult and embryonic stem cell characteristics.

Table Of Contents

Complete 2013-14 Induced Pluripotent Stem Cell Industry Report
TABLE OF CONTENTS

I. ABSTRACT

II. BACKGROUND
A. Definition
B. Discovery
C. Advantages and Disadvantages

III. TIMELINE
A. Production of iPSCs (Key Events)
B. Full Timeline of Events

IV. RESEARCH APPLICATIONS
A. Pharmaco-Toxicological Screening
B. Disease Modeling
C. Autologous Cell Transplantation
D. Breakdown of iPSC Research, By Applied Research Application

V. CHARACTERIZATION OF iPSC RESEARCH ADVANCES
A. Methods of Making iPSCs - Comparison of Methods by Downstream Application
B. Summary of iPSC Derivation Methods, by Cell Type
C. Diseases in Which iSPCs Have Been Derived from Patients

VI. COMPANIES SELLING iPSC RESEARCH PRODUCTS
A. Complete List of Companies
B. Rate of Entrants by Year

VII. TYPES OF iPSC RESEARCH PRODUCTS
A. Stem Cell Product Categories
B. iPSC Market Share Breakdown, By Product Area

VIII. COMPANIES DEVELOPING iPSC THERAPIES
A. Commerical Entities
1. Cellular Dynamics International (CDI)
2. Fate Therapeutic
3. iPerian
4. ViaCyte
5. Advanced Cell Technology (ACT)
B. Non-Commercial Organizations Developing iPSC Therapies

IX. STRATEGIC COLLABORATIONS FOR DEVELOPMENT OF iPSC PRODUCTS
A. Life Technologies (Recently Acquired by Thermo Fisher Scientific)
B. Lonza Group AG
C. EMD Millipore
D. Sigma Aldrich
E. Roslin Cells, Ltd.
F. ArunA Biomedical
G. CeeTox and Cellular Dynamics

X. MARKET TREND ANALYSIS
A. Clinical Trials
B. Grant Analysis
1. Historical Analysis
2. Future 5-Year Projection
C. Patent Analysis
D. Scientific Publication Analysis
1. Historical Data
2. Future 5-Year Projections
3. Comparison of iPSC Research Frequency, Relative to Other Cell Types
E. Search Phrase Analysis
1. Google News Search Results for iPSC Terms
2. iPSC Product Launches, by Year
F. Geographical Analysis: Domestic vs. International Status
1. Number of iPSC Labs, by Region of World
2. Percent of Total iPSC-Specific Research Funding, by Region of World
G. Additional Sources of iPSC Research Funding

XI. MARKET SIZE
A. Definition: iPSC Research Products
B. Experimental Approach
C. iPSC Research Products, Market Size
D. iPSC Research Products, 5-Year Market Projections

XII. SCIENTIST PANEL: DETAILED END-USER SURVEY
A. Survey Overview
B. Characterization of Market Survey Respondents
1. Geographic Distribution of Respondents
2. Respondent Breakdown by Industry Affiliation
3. Breakdown of Respondents by Duration of iPSC Research Activity
C. Survey Findings
1. General Scope
2. Comparison of Providers / Brand Preferences
3. Marketing Assessment
D. Terms Used in Online Product Search

XIII. STRATEGIES FOR ACCESSING THE MARKETPLACE
A. Top Research Institutions Performing Stem Cell Research
1. University of Wisconsin, including WARF, WiCell, and the WISC Bank
2. US National Institutes of Health (NIH)
3. Johns Hopkins University
4. California Institute for Regenerative Medicine
5. University of Connecticut Induced Pluripotent Stem Cell Core (iPSCC)
B. Events of Interest (2013-14)

XIV. CONCLUSIONS

APPENDIX

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