1. Market Research
  2. > Healthcare
  3. > Pathology
  4. > Cancer Market Trends
  5. > Colorectal Cancer Therapeutics in Asia-Pacific Markets to 2020 - Improved Regional Healthcare Access to Drive Uptake of High-Cost Targeted Therapies

Colorectal Cancer Therapeutics in Asia-Pacific Markets to 2020 - Improved Regional Healthcare Access to Drive Uptake of High-Cost Targeted Therapies

Summary

GBI Research, the leading business intelligence provider, has released its latest research, ‘Colorectal Cancer Therapeutics in Asia-Pacific Markets to 2020 - Improved Regional Healthcare Access to Drive Uptake of High-Cost Targeted Therapies’, which provides in-depth insights into the indication. It gives an estimation of market size for 2013 along with forecasts until 2020 for the Asia-Pacific (APAC) region, which comprises Australia, China, India and Japan. It also covers disease epidemiology, treatment algorithms, treatment patterns, in-depth analysis of clinical trials including failure rates and pipeline analysis, and analysis of deals relevant to Colorectal Cancer (CRC). The market in the APAC region was worth an estimated $1.9 billion in 2013 and is expected to grow at a Compound Annual Growth Rate (CAGR) of 6.5% to $2.9 billion in 2020. The use of targeted therapies is expected to increase in the Asia-Pacific (APAC) markets (for the purposes of this report, APAC refers to Australia, China, India and Japan only), as patient access to these more expensive agents improves. The moderate uptake of late-stage pipeline products panitumumab and Xilonix, following their expected approval, is expected to drive additional growth within this market. Others such as ramucirumab, TAS-102, TS-1, MelCancerVac will also contribute. An increasingly aging population and a year-on-year increase in the number of incident cases will provide an additional boost. However, the recent implementation of a price ceiling on essential drugs in India; anticipated pricing restrictions in China; and low access, penetration and price erosion due to generic dominance, especially in India, stand to curtail the APAC CRC market.

Scope

The report analyzes treatment usage patterns, market characterization, the pipeline, and key licensing and co-development deals in the four APAC markets of Australia, China, India and Japan. It includes -
- A brief introduction to CRC, including the disease’s pathogenesis, etiology, diagnosis and treatment algorithms
- In-depth analysis of currently marketed drugs for CRC, examining their safety, efficacy, treatment patterns and strengths/weaknesses and including a heat map that compares the drugs in terms of safety and efficacy
- A comprehensive review of the pipeline for CRC, including individual analysis of a number of late-stage pipeline drugs that are likely to enter the market during the forecast period; the pipeline is analyzed on the basis of Phase distribution, molecule type, program type, mechanism of action and molecular target
- Additional in-depth analysis of pipeline drug clinical trials by Phase, trial size, trial duration and program failure rate for each molecule type
- Multi-scenario forecast data of the market to 2020, taking into account how the market may be affected by the introduction of new drugs, the expiry of key patents on current drugs and the changes in disease epidemiology across the key developed markets
- Discussion of the drivers of and barriers to market growth
- In-depth analysis of all licensing and co-development deals that have occurred in the CRC market since 2006

Reasons to buy

The report will enhance your decision-making capability by allowing you to -
- Understand the CRC pipeline and the factors that indicate that it is becoming more innovative
- Examine detailed profiles of promising pipeline products and gain an insight into how they are likely to compete in the market and who their main competitors will be
- Follow the trends in CRC clinical trial size and duration in relation to industry averages and assess the potential risk of future developmental programs according to mechanism of action by considering the recorded clinical trial failure rates
- Observe the potential growth patterns expected for the CRC market over the forecast period, identify which countries are expected to make the biggest contribution to this growth, and devise a more effective country strategy through an understanding of key drivers and barriers in the CRC market
- Accelerate and strengthen your market position by identifying key companies for strategic partnerships

Table Of Contents

Colorectal Cancer Therapeutics in Asia-Pacific Markets to 2020 - Improved Regional Healthcare Access to Drive Uptake of High-Cost Targeted Therapies
1 Table of Contents
1 Table of Contents 5
1.1 List of Tables 7
1.2 List of Figures 7
2 Introduction 8
2.1 Colorectal Cancer 8
2.2 Symptoms 8
2.3 Epidemiology 8
2.4 Pathophysiology 9
2.4.1 Histology 9
2.4.2 Genetic Basis 9
2.4.3 Etiology 9
2.5 Diagnosis 10
2.5.1 Digital Rectal Examination 11
2.5.2 Fecal Occult Blood Test 11
2.5.3 Flexible Sigmoidoscopy 11
2.5.4 Colonoscopy 11
2.5.5 Virtual Colonoscopy 12
2.5.6 Double Contrast Barium Enema 12
2.6 Prognosis and Disease Staging 12
2.7 Treatment Options 14
2.7.1 Surgery and Radiation Therapy 14
2.7.2 Chemotherapy 15
2.7.3 Targeted Therapies 15
2.7.4 Resistance to Pharmacological Therapies 16
2.7.5 Treatment Guidelines 17
3 Marketed Products 20
3.1 Key Marketed Products 20
3.1.1 Immunotherapies 20
3.1.2 Targeted Therapies 23
3.2 Hyperthermic Intraperitoneal Chemotherapy 28
3.3 Heat Map for Marketed Products 29
4 Pipeline Analysis 31
4.1 Overall Pipeline 31
4.1.1 Pipeline Analysis by Molecule Type 32
4.1.2 Pipeline Analysis by Mechanism of Action 33
4.2 Clinical Trials 35
4.2.1 Failure Rate 35
4.2.2 Clinical Trial Size 37
4.2.3 Duration 39
4.3 Promising Drug Candidates in Pipeline 41
4.3.1 Lonsurf (TAS-102 (tipiracil + trifluridine)) - Taiho Pharmaceutical 41
4.3.2 Cyramza - ramucirumab - Eli Lilly and Company 42
4.3.3 TS-1/Teysuno (tegafur + gimeracil + oteracil) - Taiho Pharmaceutical 42
4.3.4 CPP-1X (eflornithine hydrochloride) + sulindac - Cancer Prevention Pharmaceuticals 43
4.3.5 MelCancerVac - DanDrit Biotech 44
4.3.6 Xilonix - XBiotech 45
4.3.7 Nintedanib - Boehringer Ingelheim 45
5 Market Forecast to 2020 47
5.1 Asia-Pacific Market 47
5.1.1 Treatment Use Patterns 47
5.1.2 Market Size 47
5.2 Australia 48
5.2.1 Treatment Use Patterns 48
5.2.2 Annual Cost of Therapy 49
5.2.3 Market Size 50
5.3 India 51
5.3.1 Treatment Use Patterns 51
5.3.2 Annual Cost of Therapy 52
5.3.3 Market Size 53
5.4 China 54
5.4.1 Treatment Use Patterns 54
5.4.2 Annual Cost of Therapy 55
5.4.3 Market Size 56
5.5 Japan 57
5.5.1 Treatment Use Patterns 57
5.5.2 Annual Cost of Therapy 58
5.5.3 Market Size 59
5.6 Drivers and Barriers 61
5.6.1 Drivers 61
5.6.2 Barriers 62
6 Deals and Strategic Consolidations 63
6.1 Licensing Agreements 63
6.1.1 Major Licensing Deals 64
6.2 Co-development Agreements 65
6.2.1 Major Co-development Agreements 67
7 Appendix 68
7.1 All Pipeline Drugs by Phase 68
7.1.1 Discovery 68
7.1.2 Preclinical 70
7.1.3 IND/CTA-Filed 75
7.1.4 Phase I 76
7.1.5 Phase II 80
7.1.6 Phase III 85
7.2 Market Forecasts to 2020 86
7.2.1 Asia-Pacific 86
7.2.2 Australia 86
7.2.3 India 86
7.2.4 China 87
7.2.5 Japan 87
7.3 Market Definitions 87
7.4 Abbreviations 87
7.5 References 91
7.6 References for Heat Map 95
7.7 Research Methodology 96
7.7.1 Coverage 96
7.7.2 Secondary Research 96
7.7.3 Primary Research 96
7.7.4 Therapeutic Landscape 97
7.7.5 Geographical Landscape 100
7.7.6 Pipeline Analysis 100
7.8 Expert Panel Validation 100
7.9 Contact Us 100
7.10 Disclaimer 100

1.1 List of Tables

Table 1 Colorectal Cancer Therapeutics, Global, TNM Staging, 2013 14
Table 2 Surgical Options for Colorectal Cancer 15
Table 3 Colorectal Cancer Therapeutics, Global, All Pipeline Products (Discovery), 2014 68
Table 4 Colorectal Cancer Therapeutics, Global, All Pipeline Products (Preclinical), 2014 70
Table 5 Colorectal Cancer Therapeutics, Global, All Pipeline Products (IND/CTA-Filed), 2013 75
Table 6 Colorectal Cancer Therapeutics, Global, All Pipeline Products (Phase I), 2014 76
Table 7 Colorectal Cancer Therapeutics, Global, All Pipeline Products (Phase II), 2014 80
Table 8 Colorectal Cancer Therapeutics, Global, All Pipeline Products (Phase III), 2014 85
Table 9 Colorectal Cancer Therapeutics, Asia-Pacific, Forecast Data, 2013-2020 86
Table 10 Colorectal Cancer Therapeutics, Australia, Forecast Data, 2013-2020 86
Table 11 Colorectal Cancer Therapeutics, India, Forecast Data, 2013-2020 86
Table 12 Colorectal Cancer Therapeutics, China, Forecast Data, 2013-2020 87
Table 13 Colorectal Cancer Therapeutics, Japan, Forecast Data, 2013-2020 87
Table 14: Colorectal Cancer Market, References for Heat Map 95

1.2 List of Figures

Figure 1: Colorectal Cancer Therapeutics, Global, European Society for Medical Oncology Treatment Guidelines (Colorectal Cancer at Stage I to III) 17
Figure 2: Colorectal Cancer Therapeutics, Global, European Society for Medical Oncology Treatment Guidelines (Colorectal Cancer at Stage IV) 18
Figure 3: Colorectal Cancer Therapeutics, Global, Heat Map (Marketed Products) 30
Figure 4: Colorectal Cancer Therapeutics, Global, Pipeline by Stage of Development and Program Type, 2013 31
Figure 5: Colorectal Cancer Therapeutics, Global, Pipeline by Molecule Type and Stage of Development, 2013 32
Figure 6: Colorectal Cancer Therapeutics, Global, Pipeline by Mechanism of Action and Stage of Development, 2013 34
Figure 7: Colorectal Cancer Therapeutics, Global, Clinical Trial Failure Rate (%), 2013 36
Figure 8: Colorectal Cancer Therapeutics, Global, Clinical Trial Size, 2013 38
Figure 9: Colorectal Cancer Therapeutics, Global, Clinical Trial Duration (months), 2013 40
Figure 10: Colorectal Cancer Therapeutics, Asia-Pacific, Treatment Use Patterns (‘000) ,2013-2020 47
Figure 11: Colorectal Cancer Therapeutics, Asia-Pacific, Market Size ($bn), 2013-2020 48
Figure 12: Colorectal Cancer Therapeutics, Australia, Treatment Use Patterns (‘000), 2013-2020 49
Figure 13: Colorectal Cancer Therapeutics, Australia, Annual Cost of Therapy ($), 2013-2020 50
Figure 14: Colorectal Cancer Therapeutics, Australia, Market Size ($m), 2013-2020 51
Figure 15: Colorectal Cancer Therapeutics, India, Treatment Use Patterns (‘000), 2013-2020 52
Figure 16: Colorectal Cancer Therapeutics, India, Annual Cost of Therapy ($), 2013-2020 53
Figure 17: Colorectal Cancer Therapeutics, India, Market Size ($m), 2013-2020 54
Figure 18: Colorectal Cancer Therapeutics, China, Treatment Use Patterns (‘000), 2013-2020 55
Figure 19: Colorectal Cancer Therapeutics, China, Annual Cost of Therapy ($), 2013-2020 56
Figure 20: Colorectal Cancer Therapeutics, China, Market Size ($m), 2013-2020 57
Figure 21: Colorectal Cancer Therapeutics, Japan, Treatment Use Patterns (‘000), 2013-2020 58
Figure 22: Colorectal Cancer Therapeutics, Japan, Annual Cost of Therapy ($), 2013-2020 59
Figure 23: Colorectal Cancer Therapeutics, Japan, Market Size, 2013-2020 60
Figure 24: Colorectal Cancer Therapeutics, Global, Licensing Deals by Geography, 2006-2014 63
Figure 25: Colorectal Cancer Therapeutics, Global, Licensing Deals by Phase, Value, Mechanism of Action, 2006-2014 64
Figure 26: Colorectal Cancer Market, Global, Co-development Deals by Geography and by Value, 2006-2014 66
Figure 27: GBI Research Market Forecasting Model 99

View This Report »

Get Industry Insights. Simply.

  • Latest reports & slideshows with insights from top research analysts
  • 24 Million searchable statistics with tables, figures & datasets
  • More than 10,000 trusted sources
24/7 Customer Support

Talk to Veronica

+1 718 514 2762

Purchase Reports From Reputable Market Research Publishers
Colorectal Cancer: Analytical Tool

Colorectal Cancer: Analytical Tool

  • $ 8096
  • Industry report
  • August 2016
  • by Bioseeker

Analytical Tools are cancer area specific intelligence and surveillance toolkits within a select number of hot, emerging cancer therapy areas. They are designed to empower biotech/pharma professionals ...

Colorectal cancer (mCRC)- Market Insights, Epidemiology and Market Forecast-2023

Colorectal cancer (mCRC)- Market Insights, Epidemiology and Market Forecast-2023

  • $ 4950
  • Industry report
  • November 2016
  • by Delve Insight

Note*: This report requires 5 business days to complete. DelveInsight’s Colorectal cancer (mCRC - Market Insights, Epidemiology and Market Forecast-2023” Reports provides an overview of the disease ...

Global Colorectal Cancer Diagnostics and Therapeutics Market - Growth, Trends & Forecast (2016 - 2021)

Global Colorectal Cancer Diagnostics and Therapeutics Market - Growth, Trends & Forecast (2016 - 2021)

  • $ 4250
  • Industry report
  • November 2016
  • by Mordor Intelligence LLP

The global colorectal cancer diagnostics and therapeutics market is expected to grow at a CAGR of around 6% during the forecast period 2016-2021. The market is estimated to be valued at USD 8000 million ...


Download Unlimited Documents from Trusted Public Sources

Pathology Statistics in the US and the UK

  • December 2016
    12 pages
  • Pathology  

    Digestive Syste...  

    Cancer  

  • United States  

    United Kingdom  

View report >

Pathology Statistics in the US and the UK

  • December 2016
    13 pages
  • Pathology  

    Digestive Syste...  

  • United States  

    United Kingdom  

View report >

Cancer Statistics in the UK

  • December 2016
    20 pages
  • Cancer  

  • United Kingdom  

    Europe  

View report >

ref:plp2014

Reportlinker.com © Copyright 2016. All rights reserved.

ReportLinker simplifies how Analysts and Decision Makers get industry data for their business.