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qPCR and dPCR Markets

  • October 2014
  • -
  • Kalorama Information
  • -
  • 141 pages

Real time qPCR is considered the gold standard for accurate, sensitive, and fast quantification of nucleic acid sequences. PCR technologies, specifically qPCR (quantitative PCR) and digital PCR (dPCR) show significant promise for growth. qPCR is mainly a workhorse in the research laboratory, while dPCR is helping to push the potential for diagnostic applications due to its sensitivity, precision, robustness and reproducibility. qPCR has been established for a broad range of applications including gene expression, genotyping, pathogen detection, DNA methylation analysis.

qPCR is increasingly being used in the medical diagnostic arena for diagnosis of bacterial disease, detection of antibiotic resistance, diagnosis of infectious disease and quantification of bacterial load. It is also used to detect genetic abnormalities and cancer mutations. qPCR-based diagnostic tests are expected to expand in the coming years. dPCR provides absolute measurement of copies and would seem to be the next logical step in PCR evolution. dPCR partitions the sample and reaction components into hundreds or thousands of reaction chambers to count the presence or absence of molecules. It provides greatly improved sensitivity in the detection of rare mutations and sequences. This technology will become increasingly important in the clinical application of PCR.

qPCR and dPCR Markets covers the qPCR and dPCR portion of the global IVD market. Forecast data is provided for 2014 through 2018. Compound annual growth rates (CAGRs) are provided for the 2011-2013 and 2013-2018 periods for each segment covered, with basic competitor summaries included in each segment. The forecasted market analysis for 2013-2018 is largely based on demographic trends, new developments, company performance trends, merger and acquisitions, and global expansion.

Segments Include:

Clinical Market for qPCR
Research Market for qPCR
Clinical Market for dPCR
Research Market for dPCR
qPCR Instruments
qPCR Reagents
qPCR Software and Services
dPCR Instruments
dPCR Reagents
dPCR Software and Services
The qPCR market has significant opportunities and drivers for those in the market, as well as challenges.

Kalorama outlines some of the market drivers influencing participation:

A global aging population
An increase in the number of population affected by chronic medical conditions
Advancements in gene detection and technologies
The increasing role of diagnostics in home health and remote patient care
Personalized medicine
Advancements next generation sequencing and multi-gene approaches
Kalorama also notes the challenges facing those in the market, including:
Development financial, time investment risk
Uncertain regulatory environment
Cost to patient may limit accessibility in many regions
Economic uncertainty: patients are likely to decline advanced testing in times of hardship
New technologies more difficult to develop
There are a number of issues and trends affecting the total qPCR industry. While some of these affect the entire medical industry " such as an aging population and healthcare reform" others are unique to the qPCR and dPCR. Some of the issues and trends affecting this market are:
BRIC Involvement
qPCR and Robotics
Lab-on-a-Chip Devices
Molecular Testing Reimbursement

This report focuses on qPCR, including dPCR, in medicine. The report provides product analysis for reagents, instruments, and software/services. The several different uses for qPCR technologies explored in the report are research, medical applications, and other utilizations.

Companies profiles in this report include:

Abbott Laboratories
Affymetrix
Aglient Technologies
Analytik Jena AG
Becton Dickinson
BioFire Diagnostics
bioMerieux
Bio-Rad Laboratories
Cephid
Denville Scientific
Eppendorf AG
Exiqon A/S
Fluidigm
Illumina
Kyratec
Life Techologies
Promega
Qiagen
RainDance Technologies
Roche
Sacace Biotechnologies
Takaro Bio
Thermo Fisher Scientific
WaferGen Biosystems

The analysis presented in this report is based on data from a combination of company, government, industry, institutional and private sources. It includes information from extensive literature reviews and discussions with experts in the field, including microbiologists, pathologists, hospital authorities, reimbursement specialists, research scientists, business development managers and marketing managers. This analysis is directed towards qPCR business unit managers, government procurement managers, university research directors, hospital medical research directors, and company managers looking to explore this area for performance possibilities.

Table Of Contents

qPCR and dPCR Markets
CHAPTER ONE: EXECUTIVE SUMMARY
Overview
Scope and Methodology
Total Size and Growth of the Market
Issues and Trends Affecting Market
Leading Competitors
CHAPTER TWO: INTRODUCTION TO THE qPCR AND dPCR INDUSTRY
Overview
Definitions
Polymerase Chain Reaction
PCR Applications
Medical Applications
Infectious Disease Applications
Forensic Applications
Research Applications
qPCR
Digital PCR
Droplet Digital PCR
Personalized Medicine
Potential Benefits
Privacy and Public Perception
CHAPTER THREE: INDUSTRY TRENDS
The Health Industry
Population Demographics
Life Expectancy
Chronic Disease Impact
Disease and an Aging Population
Healthcare Reform in the United States
BRIC Involvement
Regulatory Structure
qPCR and Robotics
Lab-on-a Chip (LOC) Devices
Molecular Test Reimbursement
CHAPTER FOUR: REAL TIME qPCR AND dPCR PRODUCTS
Select Reagents
Select Thermocycler Instruments
Selected Reagent and Thermocycler Suppliers
Roche
Life Technologies and Thermo Fisher Scientific
Bio-Rad
Agilent Technologies
Analytik Jena
Eppendorf
Biometra (part of Analytik Jena)
Qiagen
Cephid
Sacace
Takara Bio
Fluidigm
WaferGen Biosystems
Denville Scientific
RainDance Technologies
Bibby Scientific
Abbott Molecular
Kyratec
Select Software and Services
CHAPTER FIVE: MARKET SIZE AND GROWTH
Market Considerations
Market Overview
qPCR Market by Technology
qPCR Market by Use
qPCR
dPCR
qPCR Market by Product Type
dPCR Market by Product Type
qPCR and dPCR Market by Geographical Region
Competitive Landscape
CHAPTER SIX: COMPANY PROFILES
Introduction
Abbott Laboratories
Company Overview
Affymetrix
Company Overview
Agilent Technologies
Company Overview
Analytik Jena AG
Company Overview
Becton Dickinson and Co
Company Overview
BioFire Diagnostics, Inc
Company Overview
bioMerieux SA
Company Overview
Bio-Rad Laboratories, Inc
Company Overview
Cephid
Company Overview
Denville Scientific, Inc
Company Overview
Eppendorf AG
Company Overview
Exiqon A/S
Company Overview
Fluidigm Corporation
Company Overview
Illumina, Inc.
Company Overview
Kyratec
Company Overview
Life Technologies Corporation (part of Thermo Fisher)
Company Overview
Promega Corporation
Company Overview
Qiagen N.V.
Company Overview
RainDance Technology
Company Overview
Roche
Company Overview
Sacace Biotechnologies S. R. L.
Company Overview
Takaro Bio, Inc
Company Overview
Thermo Fisher Scientific
Company Overview
WaferGen Biosystems, Inc
Company Overview
APPENDIX: LIST OF COMPETITORS

LIST OF EXHIBITS

CHAPTER ONE: EXECUTIVE SUMMARY
Table 1-1
The qPCR Market 2011-2018
Figure 1-1
The qPCR Market 2011-2018
CHAPTER TWO: INTRODUCTION TO THE qPCR AND dPCR INDUSTRY
Table 2-1
PCR Technologies Comparison (Traditional, qPCR, Digital)
CHAPTER THREE: INDUSTRY TRENDS
Table 3-1
Total Healthcare Expenditures as a Percent of GDP by Country 1990, 2000 and 2011 (Australia, Austria, Canada, Czech Republic, Finland, France, Germany, Greece, Italy, Japan, Mexico, Switzerland, United Kingdom, United States)
Figure 3-1
Total Healthcare Expenditures as a Percent of GDP by Country 1990, 2000, and 2011 (United States, United Kingdom, Switzerland, Mexico, Japan,
Italy, Greece, Germany, France, Finland, Czech Republic, Canada, Austria, Australia)
Table 3-2
Estimated World Population by Age and Geographical Region, 2012
Figure 3-2
Estimated World Population by Age and Geographical Region, 2012
Table 3-3
Average Life Expectancy in Years by Country 1980 and 2012
Figure 3-3
Average Life Expectancy in Years by Country 1980 and 2012
Table 3-4
Selected Disease Statistics, Worldwide, as of July 2012
Figure 3-4
Elderly Support Ratio in Selected Countries (2050)
Table 3-5
BRIC and Emerging Nations Potential Market, mid-2014 (China, India, United States, Brazil, Russia, Mexico, Nigeria, Turkey, S. Korea, S. Africa, Vietnam, Poland)
Table 3-6
BRIC and Emerging Nations Healthcare Infrastructure Capacity (Russia, Poland, United States, Brazil, S. Korea, China, Mexico, Turkey, S. Africa, India, Vietnam, Nigeria)
CHAPTER FIVE: MARKET SIZE AND GROWTH
Table 5-1
The qPCR Market 2011-2018
Figure 5-1
The qPCR Market 2011-2018
Table 5-2
The Total qPCR and dPCR Market 2011-2018
Figure 5-2
The qPCR and dPCR Market Revenues 2011-2018
Table 5-3
The Total qPCR and dPCR Market by Product Type 2011-2018 (Reagents, Instruments, Software Services, Total, Percent Change)
Figure 5-3
The qPCR and dPCR Market Revenues 2011-2018
Figure 5-4
The qPCR Market Share by Use, 2013 (Clinical, Research, Other)
Figure 5-5
The dPCR Market Share by Use, 2013 (Clinical, Research, Other)
Table 5-4
The qPCR Market by Product Type 2011-2018 (Reagents, Instruments, Software and Services, Total, Percent Change)
Figure 5-6
The qPCR Market by Product Type 2011-2018 by Percent (Software/services, Instruments, Reagents)
Table 5-5
The dPCR Market by Product Type 2011-2018 (Reagents, Instruments, Software and Services, Total, Percent Change)
Figure 5-7
The Total Market by Product Type 2011-2018 by Percent (Software/services, Instruments, Reagents)
Figure 5-8
The Total qPCR Market Including the dPCR Market: Estimated Market Share by Geographic Region, 2013 (U.S., Europe, Japan, ROW)

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