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qPCR and dPCR Markets

  • October 2014
  • -
  • Kalorama Information
  • -
  • 141 pages

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Real time qPCR is considered the gold standard for accurate, sensitive, and fast quantification of nucleic acid sequences. PCR technologies, specifically qPCR (quantitative PCR) and digital PCR (dPCR) show significant promise for growth. qPCR is mainly a workhorse in the research laboratory, while dPCR is helping to push the potential for diagnostic applications due to its sensitivity, precision, robustness and reproducibility. qPCR has been established for a broad range of applications including gene expression, genotyping, pathogen detection, DNA methylation analysis.

qPCR is increasingly being used in the medical diagnostic arena for diagnosis of bacterial disease, detection of antibiotic resistance, diagnosis of infectious disease and quantification of bacterial load. It is also used to detect genetic abnormalities and cancer mutations. qPCR-based diagnostic tests are expected to expand in the coming years. dPCR provides absolute measurement of copies and would seem to be the next logical step in PCR evolution. dPCR partitions the sample and reaction components into hundreds or thousands of reaction chambers to count the presence or absence of molecules. It provides greatly improved sensitivity in the detection of rare mutations and sequences. This technology will become increasingly important in the clinical application of PCR.

qPCR and dPCR Markets covers the qPCR and dPCR portion of the global IVD market. Forecast data is provided for 2014 through 2018. Compound annual growth rates (CAGRs) are provided for the 2011-2013 and 2013-2018 periods for each segment covered, with basic competitor summaries included in each segment. The forecasted market analysis for 2013-2018 is largely based on demographic trends, new developments, company performance trends, merger and acquisitions, and global expansion.

Segments Include:

Clinical Market for qPCR
Research Market for qPCR
Clinical Market for dPCR
Research Market for dPCR
qPCR Instruments
qPCR Reagents
qPCR Software and Services
dPCR Instruments
dPCR Reagents
dPCR Software and Services
The qPCR market has significant opportunities and drivers for those in the market, as well as challenges.

Kalorama outlines some of the market drivers influencing participation:

A global aging population
An increase in the number of population affected by chronic medical conditions
Advancements in gene detection and technologies
The increasing role of diagnostics in home health and remote patient care
Personalized medicine
Advancements next generation sequencing and multi-gene approaches
Kalorama also notes the challenges facing those in the market, including:
Development financial, time investment risk
Uncertain regulatory environment
Cost to patient may limit accessibility in many regions
Economic uncertainty: patients are likely to decline advanced testing in times of hardship
New technologies more difficult to develop
There are a number of issues and trends affecting the total qPCR industry. While some of these affect the entire medical industry " such as an aging population and healthcare reform" others are unique to the qPCR and dPCR. Some of the issues and trends affecting this market are:
BRIC Involvement
qPCR and Robotics
Lab-on-a-Chip Devices
Molecular Testing Reimbursement

This report focuses on qPCR, including dPCR, in medicine. The report provides product analysis for reagents, instruments, and software/services. The several different uses for qPCR technologies explored in the report are research, medical applications, and other utilizations.

Companies profiles in this report include:

Abbott Laboratories
Affymetrix
Aglient Technologies
Analytik Jena AG
Becton Dickinson
BioFire Diagnostics
bioMerieux
Bio-Rad Laboratories
Cephid
Denville Scientific
Eppendorf AG
Exiqon A/S
Fluidigm
Illumina
Kyratec
Life Techologies
Promega
Qiagen
RainDance Technologies
Roche
Sacace Biotechnologies
Takaro Bio
Thermo Fisher Scientific
WaferGen Biosystems

The analysis presented in this report is based on data from a combination of company, government, industry, institutional and private sources. It includes information from extensive literature reviews and discussions with experts in the field, including microbiologists, pathologists, hospital authorities, reimbursement specialists, research scientists, business development managers and marketing managers. This analysis is directed towards qPCR business unit managers, government procurement managers, university research directors, hospital medical research directors, and company managers looking to explore this area for performance possibilities.

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