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  5. > Reperfusion Injury - Pipeline Review, H2 2014

Reperfusion Injury - Pipeline Review, H2 2014

  • November 2014
  • -
  • Global Markets Direct
  • -
  • 52 pages

Reperfusion Injury - Pipeline Review, H2 2014

Summary

Global Markets Direct’s, ‘Reperfusion Injury - Pipeline Review, H2 2014’, provides an overview of the Reperfusion Injury’s therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Reperfusion Injury, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Reperfusion Injury and special features on late-stage and discontinued projects.

Global Markets Direct’s report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct’s proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct’s team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope

- The report provides a snapshot of the global therapeutic landscape of Reperfusion Injury
- The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities
- The report reviews key players involved in the therapeutics development for Reperfusion Injury and enlists all their major and minor projects
- The report summarizes all the dormant and discontinued pipeline projects
- A review of the Reperfusion Injury products under development by companies and universities/research institutes based on information derived from company and industry-specific sources
- Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages
- A detailed assessment of monotherapy and combination therapy pipeline projects
- Coverage of the Reperfusion Injury pipeline on the basis of target, MoA, route of administration and molecule type
- Latest news and deals relating related to pipeline products

Reasons to buy

- Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies
- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
- Develop strategic initiatives by understanding the focus areas of leading companies
- Identify and understand important and diverse types of therapeutics under development for Reperfusion Injury
- Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline
- Devise corrective measures for pipeline projects by understanding Reperfusion Injury pipeline depth and focus of Indication therapeutics
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
- Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline

Table Of Contents

Reperfusion Injury - Pipeline Review, H2 2014
Table of Contents

Introduction 5
Global Markets Direct Report Coverage 5
Reperfusion Injury Overview 6
Therapeutics Development 7
Pipeline Products for Reperfusion Injury - Overview 7
Pipeline Products for Reperfusion Injury - Comparative Analysis 8
Reperfusion Injury - Therapeutics under Development by Companies 9
Reperfusion Injury - Therapeutics under Investigation by Universities/Institutes 10
Reperfusion Injury - Pipeline Products Glance 11
Late Stage Products 11
Clinical Stage Products 12
Early Stage Products 13
Reperfusion Injury - Products under Development by Companies 14
Reperfusion Injury - Products under Investigation by Universities/Institutes 15
Reperfusion Injury - Companies Involved in Therapeutics Development 16
Apeptico Forschung und Entwicklung GmbH 16
NeuroVive Pharmaceutical AB 17
Nyken BV 18
Vasade Biosciences, Inc. 19
Reperfusion Injury - Therapeutics Assessment 20
Assessment by Monotherapy Products 20
Assessment by Target 21
Assessment by Mechanism of Action 23
Assessment by Route of Administration 25
Assessment by Molecule Type 27
Drug Profiles 29
AP-301 - Drug Profile 29
Product Description 29
Mechanism of Action 29
RandD Progress 29
bucillamine - Drug Profile 32
Product Description 32
Mechanism of Action 32
RandD Progress 32
cyclosporine - Drug Profile 33
Product Description 33
Mechanism of Action 33
RandD Progress 33
GNX-5086 - Drug Profile 36
Product Description 36
Mechanism of Action 36
RandD Progress 36
MitoSNO - Drug Profile 37
Product Description 37
Mechanism of Action 37
RandD Progress 37
NYK-1112 - Drug Profile 38
Product Description 38
Mechanism of Action 38
RandD Progress 38
PMC-6 - Drug Profile 39
Product Description 39
Mechanism of Action 39
RandD Progress 39
Recombinant Protein to Inhibit CXCL for Cardiovascular and Immunology - Drug Profile 40
Product Description 40
Mechanism of Action 40
RandD Progress 40
Small Molecule to Agonize Opioid Delta for Reperfusion Injury - Drug Profile 41
Product Description 41
Mechanism of Action 41
RandD Progress 41
Reperfusion Injury - Recent Pipeline Updates 42
Reperfusion Injury - Dormant Projects 44
Reperfusion Injury - Discontinued Products 45
Reperfusion Injury - Product Development Milestones 46
Featured News and Press Releases 46
Feb 17, 2014: NeuroVive Treats Final Patient in European Phase III Trial on CicloMulsion 46
Aug 27, 2013: Congenia Announces Enrollment of First Healthy Volunteer in Phase 1 46
Jun 12, 2013: NeuroVive's Asian Subsidiary Receives First Milestone Payment From Sihuan Pharma 47
May 29, 2013: NeuroVive Provides Update On Ongoing Phase III Study Of CicloMulsion For Treatment Of Reperfusion Injury 47
May 27, 2013: New Chemical Compound Could Protect From Post-Heart Attack Tissue Damage, Researchers Report 48
Dec 03, 2012: NeuroVive Pharma Announces Publication Of Phase I Clinical Trial Of CicloMulsion In Clinical Drug Investigation 49
Appendix 51
Methodology 51
Coverage 51
Secondary Research 51
Primary Research 51
Expert Panel Validation 51
Contact Us 52
Disclaimer 52

List of Tables

Number of Products under Development for Reperfusion Injury, H2 2014 7
Number of Products under Development for Reperfusion Injury - Comparative Analysis, H2 2014 8
Number of Products under Development by Companies, H2 2014 9
Number of Products under Investigation by Universities/Institutes, H2 2014 10
Comparative Analysis by Late Stage Development, H2 2014 11
Comparative Analysis by Clinical Stage Development, H2 2014 12
Comparative Analysis by Early Stage Development, H2 2014 13
Products under Development by Companies, H2 2014 14
Products under Investigation by Universities/Institutes, H2 2014 15
Reperfusion Injury - Pipeline by Apeptico Forschung und Entwicklung GmbH, H2 2014 16
Reperfusion Injury - Pipeline by NeuroVive Pharmaceutical AB, H2 2014 17
Reperfusion Injury - Pipeline by Nyken BV, H2 2014 18
Reperfusion Injury - Pipeline by Vasade Biosciences, Inc., H2 2014 19
Assessment by Monotherapy Products, H2 2014 20
Number of Products by Stage and Target, H2 2014 22
Number of Products by Stage and Mechanism of Action, H2 2014 24
Number of Products by Stage and Route of Administration, H2 2014 26
Number of Products by Stage and Molecule Type, H2 2014 28
Reperfusion Injury Therapeutics - Recent Pipeline Updates, H2 2014 42
Reperfusion Injury - Dormant Projects, H2 2014 44
Reperfusion Injury - Discontinued Products, H2 2014 45

List of Figures

Number of Products under Development for Reperfusion Injury, H2 2014 7
Number of Products under Development for Reperfusion Injury - Comparative Analysis, H2 2014 8
Number of Products under Development by Companies, H2 2014 9
Number of Products under Investigation by Universities/Institutes, H2 2014 10
Comparative Analysis by Clinical Stage Development, H2 2014 12
Comparative Analysis by Early Stage Products, H2 2014 13
Assessment by Monotherapy Products, H2 2014 20
Number of Products by Top 10 Targets, H2 2014 21
Number of Products by Stage and Top 10 Targets, H2 2014 22
Number of Products by Top 10 Mechanism of Actions, H2 2014 23
Number of Products by Stage and Top 10 Mechanism of Actions, H2 2014 24
Number of Products by Top 10 Routes of Administration, H2 2014 25
Number of Products by Stage and Top 10 Routes of Administration, H2 2014 26
Number of Products by Top 10 Molecule Types, H2 2014 27
Number of Products by Stage and Top 10 Molecule Types, H2 2014 28

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