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Transitional Cell Carcinoma (Urothelial Cell Carcinoma) - Pipeline Review, H2 2014

Summary

Global Markets Direct’s, ‘Transitional Cell Carcinoma (Urothelial Cell Carcinoma) - Pipeline Review, H2 2014’, provides an overview of the Transitional Cell Carcinoma (Urothelial Cell Carcinoma)’s therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Transitional Cell Carcinoma (Urothelial Cell Carcinoma), complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Transitional Cell Carcinoma (Urothelial Cell Carcinoma) and special features on late-stage and discontinued projects.

Global Markets Direct’s report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct’s proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct’s team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope

- The report provides a snapshot of the global therapeutic landscape of Transitional Cell Carcinoma (Urothelial Cell Carcinoma)
- The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities
- The report reviews key players involved in the therapeutics development for Transitional Cell Carcinoma (Urothelial Cell Carcinoma) and enlists all their major and minor projects
- The report summarizes all the dormant and discontinued pipeline projects
- A review of the Transitional Cell Carcinoma (Urothelial Cell Carcinoma) products under development by companies and universities/research institutes based on information derived from company and industry-specific sources
- Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages
- A detailed assessment of monotherapy and combination therapy pipeline projects
- Coverage of the Transitional Cell Carcinoma (Urothelial Cell Carcinoma) pipeline on the basis of target, MoA, route of administration and molecule type
- Latest news and deals relating related to pipeline products

Reasons to buy

- Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies
- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
- Develop strategic initiatives by understanding the focus areas of leading companies
- Identify and understand important and diverse types of therapeutics under development for Transitional Cell Carcinoma (Urothelial Cell Carcinoma)
- Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline
- Devise corrective measures for pipeline projects by understanding Transitional Cell Carcinoma (Urothelial Cell Carcinoma) pipeline depth and focus of Indication therapeutics
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
- Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline

Table Of Contents

Transitional Cell Carcinoma (Urothelial Cell Carcinoma) - Pipeline Review, H2 2014
Table of Contents
Introduction 5
Global Markets Direct Report Coverage 5
Transitional Cell Carcinoma (Urothelial Cell Carcinoma) Overview 6
Therapeutics Development 7
Pipeline Products for Transitional Cell Carcinoma (Urothelial Cell Carcinoma) - Overview 7
Pipeline Products for Transitional Cell Carcinoma (Urothelial Cell Carcinoma) - Comparative Analysis 8
Transitional Cell Carcinoma (Urothelial Cell Carcinoma) - Therapeutics under Development by Companies 9
Transitional Cell Carcinoma (Urothelial Cell Carcinoma) - Pipeline Products Glance 10
Clinical Stage Products 10
Early Stage Products 11
Transitional Cell Carcinoma (Urothelial Cell Carcinoma) - Products under Development by Companies 12
Transitional Cell Carcinoma (Urothelial Cell Carcinoma) - Companies Involved in Therapeutics Development 13
Altor BioScience Corporation 13
AstraZeneca PLC 14
Boston Biomedical, Inc. 15
Daiichi Sankyo Company, Limited 16
Dendreon Corporation 17
Mirati Therapeutics Inc. 18
Novartis AG 19
Sanofi 20
Teva Pharmaceutical Industries Limited 21
Transitional Cell Carcinoma (Urothelial Cell Carcinoma) - Therapeutics Assessment 22
Assessment by Monotherapy Products 22
Assessment by Target 23
Assessment by Mechanism of Action 25
Assessment by Route of Administration 27
Assessment by Molecule Type 29
Drug Profiles 31
ALT-801 - Drug Profile 31
Product Description 31
Mechanism of Action 31
RandD Progress 31
AZD-4547 - Drug Profile 33
Product Description 33
Mechanism of Action 33
RandD Progress 33
BBI-503 - Drug Profile 35
Product Description 35
Mechanism of Action 35
RandD Progress 35
cabazitaxel - Drug Profile 37
Product Description 37
Mechanism of Action 37
RandD Progress 37
CEP-11981 - Drug Profile 39
Product Description 39
Mechanism of Action 39
RandD Progress 39
dovitinib lactate - Drug Profile 40
Product Description 40
Mechanism of Action 40
RandD Progress 40
lapuleucel-t - Drug Profile 43
Product Description 43
Mechanism of Action 43
RandD Progress 43
mocetinostat - Drug Profile 44
Product Description 44
Mechanism of Action 44
RandD Progress 44
tigatuzumab - Drug Profile 47
Product Description 47
Mechanism of Action 47
RandD Progress 47
Transitional Cell Carcinoma (Urothelial Cell Carcinoma) - Recent Pipeline Updates 49
Transitional Cell Carcinoma (Urothelial Cell Carcinoma) - Dormant Projects 54
Transitional Cell Carcinoma (Urothelial Cell Carcinoma) - Discontinued Products 55
Appendix 56
Methodology 56
Coverage 56
Secondary Research 56
Primary Research 56
Expert Panel Validation 56
Contact Us 57
Disclaimer 57

List of Tables

Number of Products under Development for Transitional Cell Carcinoma (Urothelial Cell Carcinoma), H2 2014 7
Number of Products under Development for Transitional Cell Carcinoma (Urothelial Cell Carcinoma) - Comparative Analysis, H2 2014 8
Number of Products under Development by Companies, H2 2014 9
Comparative Analysis by Clinical Stage Development, H2 2014 10
Comparative Analysis by Early Stage Development, H2 2014 11
Products under Development by Companies, H2 2014 12
Transitional Cell Carcinoma (Urothelial Cell Carcinoma) - Pipeline by Altor BioScience Corporation, H2 2014 13
Transitional Cell Carcinoma (Urothelial Cell Carcinoma) - Pipeline by AstraZeneca PLC, H2 2014 14
Transitional Cell Carcinoma (Urothelial Cell Carcinoma) - Pipeline by Boston Biomedical, Inc., H2 2014 15
Transitional Cell Carcinoma (Urothelial Cell Carcinoma) - Pipeline by Daiichi Sankyo Company, Limited, H2 2014 16
Transitional Cell Carcinoma (Urothelial Cell Carcinoma) - Pipeline by Dendreon Corporation, H2 2014 17
Transitional Cell Carcinoma (Urothelial Cell Carcinoma) - Pipeline by Mirati Therapeutics Inc., H2 2014 18
Transitional Cell Carcinoma (Urothelial Cell Carcinoma) - Pipeline by Novartis AG, H2 2014 19
Transitional Cell Carcinoma (Urothelial Cell Carcinoma) - Pipeline by Sanofi, H2 2014 20
Transitional Cell Carcinoma (Urothelial Cell Carcinoma) - Pipeline by Teva Pharmaceutical Industries Limited, H2 2014 21
Assessment by Monotherapy Products, H2 2014 22
Number of Products by Stage and Target, H2 2014 24
Number of Products by Stage and Mechanism of Action, H2 2014 26
Number of Products by Stage and Route of Administration, H2 2014 28
Number of Products by Stage and Molecule Type, H2 2014 30
Transitional Cell Carcinoma (Urothelial Cell Carcinoma) Therapeutics - Recent Pipeline Updates, H2 2014 49
Transitional Cell Carcinoma (Urothelial Cell Carcinoma) - Dormant Projects, H2 2014 54
Transitional Cell Carcinoma (Urothelial Cell Carcinoma) - Discontinued Products, H2 2014 55

List of Figures

Number of Products under Development for Transitional Cell Carcinoma (Urothelial Cell Carcinoma), H2 2014 7
Number of Products under Development for Transitional Cell Carcinoma (Urothelial Cell Carcinoma) - Comparative Analysis, H2 2014 8
Number of Products under Development by Companies, H2 2014 9
Comparative Analysis by Clinical Stage Development, H2 2014 10
Assessment by Monotherapy Products, H2 2014 22
Number of Products by Top 10 Targets, H2 2014 23
Number of Products by Stage and Top 10 Targets, H2 2014 23
Number of Products by Top 10 Mechanism of Actions, H2 2014 25
Number of Products by Stage and Top 10 Mechanism of Actions, H2 2014 25
Number of Products by Top 10 Routes of Administration, H2 2014 27
Number of Products by Stage and Top 10 Routes of Administration, H2 2014 28
Number of Products by Top 10 Molecule Types, H2 2014 29
Number of Products by Stage and Top 10 Molecule Types, H2 2014 30

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