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MediPoint: Nuclear Imaging - PET and SPECT Equipment - Global Analysis and Market Forecasts

Summary

This report examines how new technologies can emerge in the face of economic pressures that may affect the demand for nuclear imaging, and how healthcare reforms are impacting nuclear medicine.

The advent of hybrid imaging has enabled PET/CT imaging to undergo explosive growth. However, this has been at the cost of an increased demand on struggling healthcare budgets

PET and SPECT imaging are well established techniques within nuclear imaging, and are the main focus of this report

PET imaging uses Positron Emitting radioactive tracers with a short half life, to image metabolically active organs

PET combined with CT allows precise anatomical imaging of the body, identifying diseased areas depending upon the tracer used

PET/CT is most often used for cancer diagnosis

PET/MRI is a new technique that was introduced to reduce patient exposure to radiation

PET only systems are now generally considered obsolete, due to the superior imaging quality of PET/CT

SPECT imaging uses Gamma Emitting radioactive tracers with a longer half life, to image molecular processes in the body

SPECT and SPECT/CT are most often used in cardiology studies

The SPECT and SPECT/CT market is a bigger market than the PET, PET/CT and PET/MRI, because the instruments have been in longer use, are cheaper, and have become the common technique for a wide range of indications

Physicians believe more and more SPECT procedures will be replaced by PET procedures

New developments in hybrid nuclear imaging promise to further increase the utility of hybrid nuclear imaging, while significantly improving patient cost-savings and safety, through reduced need for repeat examinations.

This report focuses on the current and future industry trends within the nuclear medicine market, as well as discussing the promising pipeline products, and assessing the competitive landscape.

Key Questions Answered

- What is the current and future nuclear imaging market outlook in the developed and emerging markets? What trends are affecting the global market for both SPECT and PET imaging systems?
- Which are the key, high growth markets that manufacturers should seek to expand into? What are the types of products that are most likely to succeed?
- How many Nuclear Imaging Procedures are carried out in each of the 10 Major Markets? What does this imply for instrument adoption rates?
- What are the major unmet needs in nuclear imaging? In which areas can manufacturers help meet that need?
- What factors most influence a physician or hospital in the purchase of new nuclear imaging equipment? How much can a physician influence purchasing decisions?
- How will reimbursement changes will affect nuclear imaging. How has the Affordable Care Act affected nuclear imaging? How will it affect it in the future?
- How well are new paradigms in nuclear imaging perceived? What motivates companies to develop a new nuclear imaging modality; physician demand or legislative requirement?

Key Findings

- Nuclear Imaging is a moderately growing market, with a CAGR of 3.3% for the period to 2020
- PET/CT, SPECT, SPECT/CT and Scinitgraphy are the major techniques in nuclear imaging
- US dominates the world market for nuclear imaging equipment
- US will see lowest growth in nuclear imaging equipment thanks to reimbursement pressures
- Japan and China will present the greatest opportunities for growth, with respective market shares increasing by 75% and almost 100% during the forecasted period
- BIC nations will experience the highest growth rates in nuclear imaging equipment during the forecast period
- Non-PET nuclear imaging procedures in the developed markets (US, 5EU, Japan) likely overall to fall during forecast period, as a result of increasing reimbursement pressures and new technologies
- PET imaging procedures in all markets likely to increase during the forecast period, despite reimbursement pressures, due to increased number of indications

Scope

- Overview of Nuclear Imaging, including core technologies, estimated procedure trends and disease overview.
- Current and Future Players Companies involved in the space with portfolio assessment and SWOT analysis.
- Pipeline analysis: Comprehensive data split across different stages of development, emerging trends and nuclear imaging devices in development
- Annualized total nuclear imaging equipment market revenue for SPECT, SPECT/CT, PET, PET/CT and PET/MRI, and procedure data for 2012-2013, and forecast for seven years to 2020
- Other Key topics covered include identification of unmet needs, implications for the nuclear imaging market and how they may be overcome in the near future, reimbursement and regulatory considerations, evaluating market access for each region covered in the report
- Analysis of the market opportunities in the Nuclear Imaging market, in addition to Insightful review of the key industry drivers, restraints and challenges. Each trend is independently researched to provide qualitative analysis of its implications

Reasons to buy

- Develop and design your in-licensing and out-licensing strategies through a review of pipeline products and technologies, and by identifying the companies with the most robust pipeline in the fields of PET/CT, PET/MRI and SPECT/CT.
- Develop business strategies by understanding the trends shaping and driving the nuclear imaging market
- Drive revenues by understanding the key trends, innovative products and technologies, and companies likely to impact the nuclear imaging market in the future
- Formulate effective sales and marketing strategies by understanding the competitive landscape and by analysing the performance of various competitors
- Identify emerging players with potentially strong product portfolios and create effective counter-strategies to gain a competitive advantage
- Track device sales in the global and country-specific nuclear imaging markets from 2012-2020
- Organize your sales and marketing efforts by identifying the market categories and segments that present maximum opportunities for consolidations, investments and strategic partnerships

Table Of Contents

MediPoint: Nuclear Imaging - PET and SPECT Equipment - Global Analysis and Market Forecasts
1 Table of Contents
2 Introduction 21
2.1 Catalyst 21
2.2 Related Reports 22
3 Industry Overview 23
3.1 Nuclear Imaging Techniques 23
3.1.1 Positron Emission Tomography 23
3.1.2 Single-Photon Emission Computed Tomography 25
3.1.3 Planar Scintigraphy 25
3.1.4 Hybrid Imaging 26
3.2 Clinical Applications of Nuclear Imaging Technology 31
3.2.1 Cancer 31
3.2.2 Cardiology 33
3.2.3 Neurology 35
3.2.4 Infection and Inflammation 37
3.3 Advantages and Disadvantages of Nuclear Imaging Technologies 40
3.4 Market Access 41
3.4.1 Product Life Cycle 41
3.4.2 Purchasing Decisions 43
3.4.3 Equipment Leasing 49
3.4.4 Replacement of PET/CT by PET/MRI 49
3.5 Reimbursement 54
3.5.1 Overview 54
3.5.2 US 55
3.5.3 France 55
3.5.4 Germany 57
3.5.5 Italy 58
3.5.6 Spain 59
3.5.7 UK 60
3.5.8 Japan 61
3.5.9 Brazil 61
3.5.10 China 62
3.5.11 India 63
3.6 Procedure Trends 64
3.6.1 US 64
3.6.2 France 67
3.6.3 Germany 69
3.6.4 Italy 72
3.6.5 Spain 74
3.6.6 UK 76
3.6.7 Japan 79
3.6.8 Brazil 81
3.6.9 China 84
3.6.10 India 86
3.7 Regulatory Issues/Recalls 89
3.8 MandAs and Key Partnerships 90
3.9 Economic Impact 92
3.9.1 US 92
3.9.2 Europe 95
4 Unmet Needs 96
4.1 Overview 96
4.2 Improved Reimbursement for New Techniques 96
4.3 Lack of Binding Clinical Guidelines 100
4.4 Patient Comfort and Convenience 100
4.5 Reducing Radiation Exposure 101
4.6 Improved Scanner Performance 103
4.7 Image Processing Software Improvements 104
4.8 Increased Risk of Artifacts in Hybrid Images 106
4.9 Demand for New Radiotracers 107
4.10 Improved Clinical Input into the Design Process 109
5 Market Opportunity Analysis 110
5.1 Cheaper, Simpler Nuclear Imaging Devices 110
5.2 SPECT/CT in Developing Countries 110
5.3 Increased Demand for Teleradiology Services 113
6 Market Drivers and Barriers 115
6.1 Driver: Aging Population and Increasing Disease Prevalence 115
6.2 Driver: Referring Physician Awareness 116
6.3 Driver: Defensive medicine 117
6.4 Driver: Patient Awareness 119
6.5 Driver: Self-Referral 119
6.6 Driver: New Imaging Agents 120
6.7 Driver: Increasing Demand for Cancer Diagnostic Tests 120
6.8 Driver: Companion Diagnostic Testing 121
6.9 Barrier: Comparative Effectiveness Research 122
6.10 Barrier: Reimbursement Legislation 124
6.11 Barrier: Increasing Demand for Nuclear Imaging in Developing Markets 124
6.12 Barrier: Insurance Company Lobbying to Reduce Unnecessary Imaging 126
6.13 Barrier: Greater Payer Scrutiny of EMRs 126
6.14 Barrier: Increased Use of Appropriateness Criteria 127
6.15 Barrier: Practice Guidelines to Reduce Unnecessary Procedures 129
6.16 Barrier: Imaging Facility Accreditation 129
6.17 Barrier: Loss of Nuclear Medicine Skills 130
6.18 Barrier: High Cost of Instruments and Reagents 131
6.19 Barrier: Radiopharmaceutical Cost and Supply Difficulties 132
6.20 Barrier: Medical Device Excise Tax 135
6.21 Barrier: Hospital Consolidation 135
7 Competitive Assessment 137
7.1 Overview 137
7.2 Dedicated PET Systems 137
7.2.1 Overview 137
7.2.2 Product Profile 138
7.2.3 SWOT Analysis 139
7.3 PET/CT Systems 139
7.3.1 Overview 139
7.3.2 Product Profiles 140
7.3.3 SWOT Analysis 142
7.4 PET/MRI Systems 142
7.4.1 Overview 142
7.4.2 Product Profile 144
7.4.3 SWOT Analysis 145
7.5 Dedicated SPECT Systems 145
7.5.1 Overview 145
7.5.2 Product Profile 147
7.5.3 SWOT Analysis 148
7.6 SPECT/CT Systems 149
7.6.1 Overview 149
7.6.2 Product Profile 151
7.6.3 SWOT Analysis 152
7.7 PET/Ultrasound and SPECT/Ultrasound Systems 153
7.7.1 Overview 153
7.7.2 Product Profile 153
7.7.3 SWOT Analysis 154
8 Pipeline Assessment 155
8.1 Overview 155
8.2 Pipeline by Phases in Development 156
8.3 Product Profiles 156
8.3.1 Brain Biosciences CerePET 156
8.3.2 ECORAD Dual Modality Imager 158
8.3.3 FMI Technologies ScintiStar PET/CT 159
8.3.4 IntraMedical Imaging Marginator Beta Camera 161
8.3.5 INSERT SPECT/MRI 162
8.3.6 Nucare/Zecotek Photonics New Generation PET Scanning Device 165
8.3.7 Philips Healthcare PET Alpha Ring Detector 166
8.3.8 Photo Diagnostic Systems NeuroPET/CT 167
8.3.9 SynchroPET Breast PET/MRI 168
8.3.10 SynchroPET Wrist Scanner 169
8.3.11 SurgicEye SPECT Hybrid 170
9 Clinical Trials to Watch 172
9.1 Overview 172
9.2 Clinical Trial Profiles 172
10 Current and Future Players 175
10.1 Overview 175
10.2 Trends in Corporate Strategy 175
10.3 Company Profiles 176
10.3.1 DDD-Diagnostic 176
10.3.2 Digirad 178
10.3.3 GE Healthcare 182
10.3.4 GVI Medical Devices 187
10.3.5 Mediso Medical Imaging Systems 189
10.3.6 NeuroLogica 191
10.3.7 Neusoft Medical Systems 194
10.3.8 NuCare Medical Systems 197
10.3.9 Oncovision 199
10.3.10 Philips Healthcare 201
10.3.11 Shimadzu 208
10.3.12 Siemens Healthcare 213
10.3.13 SurgicEye 219
10.3.14 Toshiba Medical 222
10.3.15 Other Companies 227
11 Market Outlooks 230
11.1 Company Market Share Analysis 230
11.1.1 Global Overview 230
11.1.2 US 231
11.1.3 France 231
11.1.4 Germany 232
11.1.5 Italy 233
11.1.6 Spain 234
11.1.7 UK 235
11.1.8 Japan 236
11.1.9 Brazil 237
11.1.10 China 238
11.1.11 India 239
11.2 Market Segment Share 240
11.2.1 SPECT and SPECT/CT 240
11.2.2 PET, PET/CT and PET/MRI 241
11.3 By Geography 243
11.3.1 Global Overview 243
11.3.2 US 246
11.3.3 France 248
11.3.4 Germany 250
11.3.5 Italy 252
11.3.6 Spain 255
11.3.7 UK 257
11.3.8 Japan 259
11.3.9 Brazil 262
11.3.10 China 265
11.3.11 India 268
12 Appendix 271
12.1 Abbreviations 271
12.2 Bibliography 276
12.3 Methodology 307
12.3.1 Overview 307
12.3.2 Coverage 307
12.3.3 Secondary Research 307
12.4 Physicians and Specialists Included in This Study 309
12.5 Primary Research 311
12.5.1 Primary Research - Key Opinion Leader Interviews 311
12.5.2 Expert Panel Validation 311
12.5.3 Stakeholder Survey 312
12.6 Forecasting Methodology 314
12.7 About the Authors 315
12.7.1 Andrew Thompson, PhD, Senior Analyst 315
12.7.2 Priya Radhakrishnan, MBA, Director, Medical Devices 315
12.7.3 Bonnie Bain, PhD, Global Head of Healthcare 316
12.8 About GlobalData 317
12.9 Disclaimer 317

1.1 List of Tables

Table 1: Applications of Nuclear Imaging 31
Table 2: FDG-PET Diagnostic Accuracy for Specific Cancers 32
Table 3: Potential Clinical Benefits of Hybrid Nuclear Imaging in Cardiology 35
Table 4: Applications of PET Imaging in Non-Cancer Neurology 36
Table 5: Applications of SPECT Imaging in Non-Cancer Neurology 36
Table 6: Characteristics of SPECT, PET, Ultrasound, CT, and MRI 41
Table 7: The Age of Canada's Hospital-Based Medical Technology Inventories, Relative to ECCREI Rules, 2009 42
Table 8: Nuclear Imaging Trends in US, 2012-2020 67
Table 9: Nuclear Imaging Trends in France, 2012-2020 69
Table 10: Nuclear Imaging Trends in Germany, 2012-2020 71
Table 11: Nuclear Imaging Trends in Italy, 2012-2020 73
Table 12: Nuclear Imaging Trends in Spain, 2012-2020 75
Table 13: Nuclear Imaging Trends in UK, 2012-2020 78
Table 14: Nuclear Imaging Trends in Japan, 2012-2020 80
Table 15: Nuclear Imaging Trends in Brazil, 2012-2020 83
Table 16: Nuclear Imaging Trends in China 2012-2020 85
Table 17: Nuclear Imaging Trends in India, 2012-2020 88
Table 18: Recent Device Recalls in the Nuclear Imaging Market 89
Table 19: Recent Key Events in the Nuclear Imaging Market 91
Table 20: Nuclear Imaging Market Drivers and Barriers 115
Table 21: Duplicate Diagnostic Test Incidence in France, Germany, UK, and US 127
Table 22: Dedicated PET Scanners 138
Table 23: Dedicated PET SWOT Analysis 139
Table 24: PET/CT Scanners 140
Table 25: PET/CT SWOT Analysis 142
Table 26: PET/MRI Systems 144
Table 27: PET/MRI SWOT Analysis 145
Table 28: Dedicated SPECT Systems 147
Table 29: Dedicated SPECT SWOT Analysis 148
Table 30: SPECT/CT Systems 151
Table 31: SPECT/CT SWOT Analysis 152
Table 32: SPECT-Ultrasound Systems 153
Table 33: SPECT/Ultrasound SWOT Analysis 154
Table 34: Nuclear Imaging Pipeline, 2014 156
Table 35: CerePET SWOT Analysis 158
Table 36: ECORAD Dual Modality Imager SWOT Analysis 159
Table 37: ScintiStar PET/CT SWOT Analysis 161
Table 38: Marginator SWOT Analysis 162
Table 39: INSERT SPECT-MRI SWOT Analysis 165
Table 40: Nucare/Zecotek Photonics New Generation PET Scanning Device SWOT Analysis 166
Table 41: PET Alpha Ring Detector 167
Table 42: NeuroPET/CT Scanner SWOT Analysis 168
Table 43: SynchroPET Breast PET/MRI SWOT Analysis 169
Table 44: SynchroPET Wrist Scanner 170
Table 45: SurgicEye SPECT/Ultrasound device SWOT Analysis 171
Table 46: Key Clinical Trials 173
Table 47: Company Profile - DDD-Diagnostic 176
Table 48: DDD-Diagnostic SWOT Analysis 178
Table 49: Company Profile - Digirad 179
Table 50: Digirad SWOT Analysis 182
Table 51: Company Profile - GE Healthcare 183
Table 52: GE Healthcare Product Portfolio 184
Table 53: GE Healthcare SWOT Analysis 187
Table 54: Company Profile - GVI Medical Devices 188
Table 55: GVI Medical Devices SWOT Analysis 189
Table 56: Company Profile - Mediso Medical Imaging Systems 190
Table 57: Mediso Medical Imaging Systems SWOT Analysis 191
Table 58: Company Profile - Neurologica 192
Table 59: Neurologica SWOT Analysis 194
Table 60: Company Profile - Neusoft Medical Systems 195
Table 61: Neusoft Medical Systems SWOT Analysis 197
Table 62: Company Profile - NuCare Medical Systems 198
Table 63: Nucare Medical Systems SWOT Analysis 199
Table 64: Company Profile - Oncovision 200
Table 65: Oncovision SWOT Analysis 201
Table 66: Company Profile - Philips Healthcare 202
Table 67: Philips Healthcare SWOT Analysis 208
Table 68: Company Profile - Shimadzu 209
Table 69: Shimadzu SWOT Analysis 213
Table 70: Company Profile - Siemens Healthcare 214
Table 71: Siemens Healthcare SWOT Analysis 219
Table 72: Company Profile - SurgicEye 220
Table 73: SurgicEye SWOT Analysis 222
Table 74: Company Profile - Toshiba Medical 223
Table 75: Toshiba Medical SWOT Analysis 226
Table 76: Other Companies in the Nuclear Imaging Market, 2014 227
Table 77: Global Market Value Forecast by Market Segment for SPECT and SPECT/CT (2012-2020) 241
Table 78: Global Market Value Forecast by Market Segment for PET, PET/CT and PET/MRI (2012-2020) 242
Table 79: Global Sales of PET and SPECT Imaging Systems, 2012-2020 244
Table 80: United States Market Value Forecast by Market Sub-segment (2012-2020) 246
Table 81: France Market Value Forecast by Market Sub segment (2012-2020) 248
Table 82: Germany Market Value Forecast by Market Sub segment (2012-2020) 250
Table 83: Italy Market Value Forecast by Market Sub-segment (2012-2020) 253
Table 84: Spain Market Value Forecast by Market Sub-segment (2012-2020) 255
Table 85: UK Market Value Forecast by Market Sub-segment (2012-2020) 257
Table 86: Japan Market Value Forecast by Market Sub-segment (2012-2020) 260
Table 87: Brazil Market Value Forecast by Market Sub-segment (2012-2020) 262
Table 88: China Market Value Forecast by Market Sub-segment (2012-2020) 265
Table 89: India Market Value Forecast by Market Sub-segment (2012-2020) 268
Table 90: Primary Research Summary 312
Table 91: Primary Research Participants Affiliation 313

1.2 List of Figures

Figure 1: Cyclotron Distribution in 10 Countries 24
Figure 2: Localization of Tumor in Chest Cavity by PET, CT, and PET/CT 28
Figure 3: Mutually Beneficial Effects of PET/MRI Imaging 30
Figure 4: Nuclear Imaging Trends in US, 2012-2020 66
Figure 5: Nuclear Imaging Trends in France, 2012-2020 68
Figure 6: Nuclear Imaging Trends in Germany, 2012-2020 71
Figure 7: Nuclear Imaging Trends in Italy, 2012-2020 73
Figure 8: Nuclear Imaging Trends in Spain, 2012-2020 75
Figure 9: Nuclear Imaging Trends in UK, 2012-2020 78
Figure 10: Nuclear Imaging Trends in Japan, 2012-2020 80
Figure 11: Nuclear Imaging Trends in Brazil, 2012-2020 83
Figure 12: Nuclear Imaging Trends in China, 2012-2020 85
Figure 13: SPECT and PET Imaging Trends in India, 2012-2020 87
Figure 14: Total Medicare Expenditures for Imaging Services Paid Under the Physician Fee Schedule, 2000-2006 93
Figure 15: Imaging Utilization Rates (Number of Outpatient Visits with MRI/CT per 1,000 Persons), by Year in the US 116
Figure 16: Global Company Market Shares for Nuclear Imaging Equipment (2012) 230
Figure 17: US Company Market Shares for Nuclear Imaging Equipment (2012) 231
Figure 18: France Company Market Shares for Nuclear Imaging Equipment (2012) 232
Figure 19: Germany Company Market Shares for Nuclear Imaging Equipment (2012) 233
Figure 20: Italy Company Market Shares for Nuclear Imaging Equipment (2012) 234
Figure 21: Spain Company Market Shares for Nuclear Imaging Equipment (2012) 235
Figure 22: UK Company Market Shares for Nuclear Imaging Equipment (2012) 236
Figure 23: Japan Company Market Shares for Nuclear Imaging Equipment (2012) 237
Figure 24: Brazil Company Market Shares for Nuclear Imaging Equipment (2012) 238
Figure 25: China Company Market Shares for Nuclear Imaging Equipment (2012) 239
Figure 26: India Company Market Shares for Nuclear Imaging Equipment (2012) 240
Figure 27: Global Market Value Forecast by Market Segment for SPECT and SPECT/CT (2012-2020) 241
Figure 28: Global Market Value Forecast by Market Segment for PET, PET/CT, and PET/MRI (2012-2020) 243
Figure 29: Global Sales of PET and SPECT Imaging Systems, 2012-2020 244
Figure 30: Global Market Share of Nuclear Imaging, 2012 and 2020 245
Figure 31: United States Market Value Forecast by Market Sub-segment (2012-2020) 247
Figure 32: France Market Value Forecast by Market Subsegment (2012-2020) 249
Figure 33: Germany Market Value Forecast by Market Sub segment (2012-2020) 251
Figure 34: Italy Market Value Forecast by Market Sub segment (2012-2020) 253
Figure 35: Spain Market Value Forecast by Market Sub-segment (2012-2020) 256
Figure 36: UK Market Value Forecast by Market Sub-segment (2012-2020) 258
Figure 37: Japan Market Value Forecast by Market Sub segment (2012-2020) 260
Figure 38: Brazil Market Value Forecast by Market Sub segment (2012-2020) 263
Figure 39: China Market Value Forecast by Market Sub-segment (2012-2020) 266
Figure 40: India Market Value Forecast by Market Sub segment (2012-2020) 269
Figure 41: Primary Research Summary 312
Figure 42: Primary Research Participants Affiliation 313

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