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US Biocompatible Materials Market

  • December 2014
  • -
  • Freedonia
  • -
  • 333 pages

US demand to grow 5.4% annually through 2018

US demand for biocompatible materials is forecast to grow 5.4 percent annually to $5.5 billion in 2018, representing 2.0 billion pounds. Reflecting quality, performance, and cost advantages in a broad range of applications, synthetic polymers will remain the top-selling product group by far, accounting for 56 percent of 2018 revenues. Ceramic materials will generate the fastest growth in demand among all biocompatible materials as advances in nanotechnology lead to the introduction of new and improved compounds for orthopedic implants, spinal fixation devices, and dental repair and restoration products. Spurred by increasing applications in cosmetic surgery, wound management, and arthritis therapy, hyaluronic acid will post the fastest revenue gains among natural biocompatible polymers. Titanium and titanium alloys will fare the best in the marketplace among biocompatible metals as high strength, light weight, and shape memory advantages promote their expanding use in cardiac, orthopedic, and dental implants. Competition from alternative polymer materials will hold down demand for other biocompatible metals, including precious metals and stainless steel.

Engineered resins to pace synthetic polymers segment

Demand for synthetic biocompatible polymers will reach $3 billion in 2018, up 4.9 percent annually from 2013. Engineered resins -- especially silicone, sulfone, and polyketone materials -- will command the fastest revenue growth based on quality and safety advantages in high value-added catheters and implants. By contrast, demand for polyvinyl chloride, the most widely used biocompatible resin, will expand slowly due to recurring safety concerns and competition from improved grades of polypropylene and thermoplastic polyesters.

Natural biopolymer demand to exceed $1 billion in 2018

Widening use in drug delivery systems, cosmetic implants, tissue engineering products, wound management supplies, and orthopedic pain therapies will boost US demand for natural biocompatible polymers 5.5 percent per year to $1.1 billion in 2018. Cellulose polymers and starch derivatives will remain the topselling product groups based on well established performance results in drug formulations and delivery systems. Hyaluronic acid will generate the fastest revenue gains spurred by expanding applications in injectable arthritis treatments. Lastly, collagen will continue to fare well in the marketplace following upward trends in the volume of cosmetic surgical procedures.

Nanocomposites to see wider use in ceramics

Advances in alumina-zirconia nanocomposites will broaden the use of biocompatible ceramics in dental and orthopedic implants. Due to their high density structure, these nanocomposites incorporate greater resistance to cracking, a widespread problem usually seen in joint replacements composed of conventional ceramics. Biocompatible metals will retain applications in a number of dental and medical implants. Within this product group, titanium and titanium alloys will realize the fastest revenue growth based on high strength, low modulus, and strong body fluid resistance advantages in such products as joint replacement systems, dental implants, fusion cages, trauma fixation devices, and stents.

Study coverage

This upcoming industry study, Biocompatible Materials, presents historical demand data (2003, 2008 and 2013) plus forecasts for 2018 and 2023 by material and application. The study also assesses key market environment factors, examines industry structure, evaluates company market share and profiles 32 competitors in the US industry.

Table Of Contents

US Biocompatible Materials Market
TABLE OF CONTENTS
INTRODUCTION x
I. EXECUTIVE SUMMARY 1
II. MARKET ENVIRONMENT 4
General 4
Macroeconomic Environment 5
Population Trends 7
Healthcare Trends 9
Health Insurance and Healthcare Reform 10
Acute Conditions 13
Chronic Conditions 14
National Health Expenditures 17
Spending Categories 18
Funding Sources 22
Medical Providers 25
Hospitals 26
Physicians 27
Dentists 28
Outpatient Facilities 29
Skilled Nursing Homes 32
Other Medical Providers 33
Patient Activity 34
Hospital Activity 35
Surgical Procedures 36
Outpatient Episodes 37
Diagnostic Tests 38
Medical Product Shipments 40
Pharmaceuticals 41
Medical Supplies and Devices 42
Plastics Industry Overview 45
Biocompatible Materials Historical Demand Patterns 49
US Trade 51
International Markets 53
Regulatory Considerations 54
Medical Devices 55
Drug Delivery Systems 56
III. PRODUCTS 58
General 58
Synthetic Polymers 60
Synthetic Biocompatible Engineered Polymers 62
Silicones 64
Thermoplastic Elastomers 73
Polycarbonate 81
Fluoropolymers 84
Acrylonitrile-Butadiene-Styrene 90
Thermoplastic Polyesters 93
Sulfone Resins 96
Nylon 100
Other Biocompatible Engineered Polymers 103
Synthetic Biocompatible Commodity Polymers 114
Polyvinyl Chloride 115
Polypropylene 120
Acrylic Resins 123
Thermoset Polyurethane 129
Low Density Polyethylenes 131
High Density Polyethylene 135
Polystyrene 137
Natural Biocompatible Polymers 138
Cellulose Polymers 140
Microcrystalline Cellulose 141
Hydroxypropyl Methylcellulose 143
Ethyl Cellulose 145
Methyl Cellulose 145
Carboxymethylcellulose 146
Croscarmellose Sodium 147
Other Cellulose Polymers 148
Starch Compounds 151
Pregelatinized Starch 153
Sodium Starch Glycolate 154
Native Starch 155
Cyclodextrins 156
Maltodextrin 156
Dextrin 157
Collagen 157
Applications 158
Producers 161
Other Natural Biocompatible Polymers 161
Hyaluronic Acid 162
Alginates 164
Carrageenan 167
All Other Natural Biocompatible Polymers 168
Biocompatible Ceramics 172
Alumina 175
Porcelain 177
Hydroxyapatite 179
Zirconia 180
Other Ceramic Materials 182
Bioactive Glass 183
Glass Ionomer 184
Pyrolytic Carbon 185
Tricalcium Phosphate 185
Biocompatible Metals 186
Precious Metals 188
Gold 189
Silver 190
Other Precious Metals 192
Stainless Steel 193
Titanium 195
Other Biocompatible Metals 198
IV. APPLICATIONS 201
General 201
Surgical and Medical Instruments 205
Surgical Appliances and Supplies 207
Dental Products and Materials 215
Drug Delivery Products 218
Electromedical Equipment 221
Diagnostic Products 223
Ophthalmic Goods 225
V. INDUSTRY STRUCTURE 227
General 227
Market Share 230
Competitive Strategies 238
Mergers and Acquisitions 239
Cooperative Agreements 240
Research and Development 244
Marketing and Distribution 245
Manufacturing 247
Company Profiles 248
AdvanSource Biomaterials Corporation 249
Allegheny Technologies Incorporated 251
AlphaGary, see MexichemB
Archer-Daniels-Midland Company 254
Ashland Incorporated 255
Axiall Corporation 257
BASF SE 259
Baxter International Incorporated 265
Bayer AG 268
Cargill Incorporated 271
Celanese Corporation 273
Chevron Phillips Chemical Company LLC 276
CP Kelco US, see Huber (JM)
Croda International plc 277
Dow Chemical Company 278
Dow Corning Corporation 282
DuPont (EI) de Nemours 284
Eastman Chemical Company 287
Evonik Industries AG 289
Exxon Mobil Corporation 293
FMC Corporation 295
Fortron Industries, see Celanese
Genzyme, see Sanofi
Georgia Gulf, see Axiall
Glasforms, see PolyOne
GLS Thermoplastic Elastomers, see PolyOne
Huber (JM) Corporation 298
Mexichem SAB de CV 299
Momentive Performance Materials Holdings LLC 301
NatureWorks, see Cargill
NovaMatrix, see FMC
Occidental Petroleum Corporation 303
Oxy Vinyls, see Occidental Petroleum
Pluromed, see Sanofi
PolyOne Corporation 305
Royal DSM NV 309
Sanofi 313
Solvay SA 315
SolVin, see BASF and Solvay
Stryker Corporation 318
Styrolution Group, see BASF
Teknor Apex Company 323
Teleflex Incorporated 325
Zeus Industrial Products Incorporated 327
Other Companies in the Biocompatible Materials Industry 329

LIST OF TABLES
SECTION I -- EXECUTIVE SUMMARY
Summary Table 3
SECTION II -- MARKET ENVIRONMENT
1 Macroeconomic Indicators 6
2 Resident Population by Age Group 9
3 Health Insurance Coverage of the US Population 12
4 Acute Conditions by Type 14
5 Chronic Conditions by Type 17
6 National Health Expenditures by Spending Categories 22
7 National Health Expenditures by Payment Source 25
8 Hospitals 27
9 Physicians 28
10 Dentists 29
11 Outpatient Facilities 32
12 Skilled Nursing Homes 33
13 Other Medical Providers 34
14 Hospital Activity 36
15 Surgical Procedures 37
16 Outpatient Episodes 38
17 Diagnostic Tests 40
18 Medical Product Shipments by Type 41
19 Plastic Resin Supply and Demand 49
20 Biocompatible Materials: Historical Demand Patterns,
2003-2013 51
21 US Trade in Biocompatible Materials 52
22 World Biocompatible Materials Demand by Region 54
SECTION III -- PRODUCTS
1 Biocompatible Materials Demand by Product Group 59
2 Synthetic Biocompatible Polymer Demand by Resin Group 62
3 Synthetic Biocompatible Engineered Polymers Demand
by Resin Group 63
4 Biocompatible Silicone Demand by Application 66
5 Biocompatible Thermoplastic Elastomer (TPE) Demand
by Application 75
6 Biocompatible Polycarbonate Demand by Application 82
7 Biocompatible Fluoropolymers Demand by Application 86
8 Biocompatible Acrylonitrile-Butadiene-Styrene Demand
by Application 91
9 Biocompatible Thermoplastic Polyesters Demand
by Application 94
10 Biocompatible Sulfone Resins Demand by Application 97
11 Biocompatible Nylon Demand by Application 101
12 Other Biocompatible Engineered Polymers Demand
by Application 104
13 Synthetic Biocompatible Commodity Polymer Demand
by Resin Group 114
14 Biocompatible Polyvinyl Chloride (PVC) Demand
by Application 116
15 Biocompatible Polypropylene Demand by Application 121
16 Biocompatible Acrylic Resins Demand by Application 125
17 Biocompatible Thermoset Polyurethane (PUR) Demand
by Application 130
18 Biocompatible Low Density Polyethylenes (LDPEs) Demand
by Application 132
19 Biocompatible High Density Polyethylene (HDPE) Demand
by Application 136
20 Biocompatible Polystyrene Demand by Application 137
21 Natural Biocompatible Polymer Demand by Type 139
22 Biocompatible Cellulose Polymer Demand by Type
and Application 141
23 Biocompatible Starch Compounds Demand by Application 153
24 Biocompatible Collagen Demand by Application 158
25 Other Natural Biocompatible Polymer Demand by Type
and Application 162
26 Biocompatible Ceramics Demand by Type 174
27 Biocompatible Alumina Demand by Application 177
28 Biocompatible Porcelain Demand by Application 178
29 Biocompatible Hydroxyapatite Demand by Application 180
30 Biocompatible Zirconia Demand by Application 182
31 Other Biocompatible Ceramics Demand by Application 183
32 Biocompatible Metals Demand by Type 187
33 Biocompatible Precious Metals Demand by Application 189
34 Biocompatible Stainless Steel Demand by Application 195
35 Biocompatible Titanium Demand by Application 198
36 Other Biocompatible Metals Demand by Application 200
SECTION IV -- APPLICATIONS
1 Biocompatible Materials Demand by Application 204
2 Surgical and Medical Instruments: Biocompatible Materials
Demand 207
3 Surgical Appliances and Supplies: Biocompatible Materials
Demand 209
4 Dental Products and Materials: Biocompatible Materials
Demand 215
5 Drug Delivery Products: Biocompatible Materials Demand 219
6 Electromedical Equipment: Biocompatible Materials
Demand 223
7 Diagnostic Products: Biocompatible Material Demand 224
8 Ophthalmic Goods: Biocompatible Materials Demand 226
SECTION V -- INDUSTRY STRUCTURE
1 US Biocompatible Materials Sales by Company, 2013 228
2 Selected Acquisitions and Divestitures 240
3 Selected Cooperative Agreements 242

LIST OF CHARTS
SECTION III -- PRODUCTS
1 Biocompatible Materials Demand by Product Group, 2013 60
2 Synthetic Biocompatible Engineered Polymers Demand
by Resin Group, 2013 64
3 Synthetic Biocompatible Commodity Polymer Demand
by Resin Group, 2013 115
4 Natural Biocompatible Polymer Demand by Type, 2013 140
5 Biocompatible Ceramics Demand by Type, 2013 175
6 Biocompatible Metals Demand by Type, 2013 188
SECTION IV -- APPLICATIONS
1 Biocompatible Materials Demand by Application, 2013 205
SECTION V -- INDUSTRY STRUCTURE
1 US Biocompatible Materials Industry Market Share, 2013 231

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