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The Market for Personalized Gene Therapy Treatments for Cancer

  • December 2014
  • -
  • Kalorama Information
  • -
  • 150 pages

This report, The Market for Personalized Gene Therapy Treatments For Cancer provides an exhaustive review of the market potential for relatively new approach in cancer research. It involves modification of genes instead of using a surgical method or chemical drug product. Essentially, gene therapies replace an abnormal gene with a normal gene, or changes the response of a gene (turn on or off). Not all of the approaches to gene therapy are the same, and different cancers appear to respond better to different therapies.

Several gene therapy technologies have the ability to work in combination with other treatment options to enhance the effectiveness of a therapeutic regimen. Gene therapy is also designed to target specific cells making treatment much less damaging to healthy cells.

This report discusses those treatments and estimates market size and market potential for personalized medicine using gene therapy. As part of its data offering, the report provides disease incidence, gene therapy product developments and market forecasts for the following types of cancer:

Bladder Cancer
Brain Cancer
Breast Cancer
Head & Neck
Colorectal Cancer
Leukemia Cancer
Liver Cancer
Lung Cancer
Lymphoma
Melanoma
Leukemia
Pancreatic Cancer
Prostate Cancer
Ovarian Cancer
Other Cancer

In addition the report provides:
Overview of Gene Therapy
Overall Market Size and Forecast
Cancer Therapeutic Market Totals
Discussion of Somati vs. Germ Line Gene Therapy
R&D Activities
Company Profiles

Historically, cancer treatments have been very invasive and detrimental process to the body. However, there are numerous new techniques available for those with cancer that are not as invasive and detrimental to the body as a whole. These treatments range from the severely alternative to the more traditional. Newer alternative treatments are more precise and much less invasive as some of the traditional methods. Gene therapy is the most prominent new form of these alternative treatments. It is being studied as a way to change how a cell functions, for example, by stimulating the cells of the immune system to attack cancer cells.

Companies discussed in this report include those which have registered trials in Phase I through Phase III development and have promising development activities. These include:
Adaptimmune Ltd.
Advantagene, Inc.
Amgen, Inc.
Bellicum Pharmaceuticals, Inc.
BioCancell Ltd.
Blubird Bio
Celgene
Celsion Corporation
Chengdu Shi Endor Biological Engineering Technology Co., Ltd.
Cold Genesys, Inc.
Genprex, Inc.
MaxiVax SA
Momotaro-Gene, Inc.
MultiVir, Inc.
OncoSec Medical, Inc.
Sevion Therapeutics, Inc.
SynerGene Therapeutics, Inc.
Takara Bio, Inc.
Tocagen, Inc.
VBL Therapeutics Ltd.
Ziopharm Oncology, Inc.

Table Of Contents

The Market for Personalized Gene Therapy Treatments for Cancer
EXECUTIVE SUMMARY
Overview and Scope of Study
Methodology
How Personalized Medicine is Changing the Cancer Market
Market Potential for Gene Therapy in Cancer
GENE THERAPY OVERVIEW
Genetics
Reducing Costs
What is Gene Therapy?
Types of Gene Therapy
Somatic Gene Therapy
Germ Line Gene Therapy
Gene Therapy Applications
Regulation Overview
Orphan Drug Designation Incentives
Fast Track, Breakthrough Therapy, Accelerated Approval and Priority Review
Fast Track
Breakthrough Therapy
Accelerated Approval
Priority Review
State 'Right to Try' Laws
CANCER AND GENE THERAPY
How has the Cancer Treatment Market Evolved?
Pharmacogenomics
Using Gene Therapy to Treat Cancer
Viral Vectors and DNA Therapies
Curing CancerThe Ultimate Goal
Global Cancer Impact
Gene Therapy and Cancer Development Overview
Development Risk
A Recent Disappointment in Novel Cancer Therapy Development Allovectin-7
Development Programs
Insurance and Reimbursement Issues
GENE THERAPY OUTLOOK IN BLADDER CANCER
Bladder Cancer Overview
Trends in Incidence and Mortality
Current Approaches to Treatment
Gene Therapy Research Activities
BioCancell Ltd.
Research Activities
Company Background
Cold Genesys, Inc.
Research Activities
Company Background
Market Opportunity
Current Market for Treating Bladder Cancer
Potential Market for Gene Therapy in Bladder Cancer
GENE THERAPY OUTLOOK IN BRAIN CANCER
Brain Cancer Overview
Glioblastoma
Neuroblastoma
Trends in Incidence and Mortality
Current Approaches to Treatment
Gene Therapy Research Activities
Advantagene, Inc.
Research Activities
Company Background
BioCancell Ltd.
Research Activities
Company Background
Celsion Corporation
Research Activities
Company Background
Tocagen, Inc.
Research Activities
Company Background
VBL Therapeutics Ltd.
Research Activities
Company Background
Market Opportunity
Current Market for Treating Brain Cancer
Potential Market for Gene Therapy in Brain Cancer
GENE THERAPY OUTLOOK IN BREAST CANCER
Breast Cancer Overview
Trends in Incidence and Mortality
Current Approaches to Treatment
Gene Therapy Research Activities
ZIOPHARM Oncology, Inc.
Research Activities
Company Background
Market Opportunity
Current Market for Treating Breast Cancer
Potential Market for Gene Therapy in Breast Cancer
GENE THERAPY OUTLOOK IN COLORECTAL CANCER
Colorectal Cancer Overview
Trends in Incidence and Mortality
Current Approaches to Treatment
Gene Therapy Research Activities
MultiVir, Inc.
Research Activities
Company Background
Market Opportunity
Current Market for Treating Colorectal Cancer
Potential Market for Gene Therapy in Colorectal Cancer
GENE THERAPY OUTLOOK IN HEAD and NECK CANCER
Head and Neck Cancer Overview
Trends in Incidence and Mortality
Current Approaches to Treatment
Gene Therapy Research Activities
Chengdu Shi Endor Biological Engineering Technology Co., Ltd
Research Activities
Market Opportunity
Current Market for Treating Head and Neck Cancer
Potential Market for Gene Therapy in Head and Neck Cancer
GENE THERAPY OUTLOOK IN LEUKEMIA
Leukemia Overview
Trends in Incidence and Mortality
Current Approaches to Treatment
Gene Therapy Research Activities
Bellicum Pharmaceuticals, Inc.
Research Activities
Company Background
Market Opportunity
Current Market for Treating Leukemia
Potential Market for Gene Therapy in Leukemia
GENE THERAPY OUTLOOK IN LIVER CANCER
Liver Cancer Overview
Trends in Incidence and Mortality
Current Approaches to Treatment
Gene Therapy Research Activities
MultiVir, Inc.
Research Activities
Company Background
Market Opportunity
Current Market for Treating Liver Cancer
Potential Market for Gene Therapy in Liver Cancer
GENE THERAPY OUTLOOK IN LUNG CANCER
Lung Cancer Overview
Trends in Incidence and Mortality
Current Approaches to Treatment
Gene Therapy Research Activities
Genprex, Inc.
Research Activities
Company Background
Market Opportunity
Current Market for Treating Lung Cancer
Potential Market for Gene Therapy in Lung Cancer
GENE THERAPY OUTLOOK IN LYMPHOMA
Lymphoma Overview
Non-Hodgkin's Lymphoma
Hodgkin's Lymphoma
Trends in Incidence and Mortality
Current Approaches to Treatment
Gene Therapy Research Activities
Bellicum Pharmaceuticals, Inc.
Research Activities
Company Background
Sevion Therapeutics, Inc.
Research Activities
Company Background
OncoSec Medical, Inc.
Research Activities
Company Background
Takara Bio, Inc.
Research Activities
Company Background
Market Opportunity
Current Market for Treating Lymphoma
Potential Market for Gene Therapy in Lymphoma
GENE THERAPY OUTLOOK IN MELANOMA
Melanoma Overview
Trends in Incidence and Mortality
Current Approaches to Treatment
Gene Therapy Research Activities
Adaptimmune Limited
Research Activities
Company Background
Amgen, Inc.
Research Activities
Company Background
OncoSec Medical, Inc.
Research Activities
Company Background
ZIOPHARM Oncology, Inc.
Research Activities
Company Background
Market Opportunity
Current Market for Treating Melanoma
Potential Market for Gene Therapy in Melanoma
GENE THERAPY OUTLOOK IN OVARIAN CANCER
Ovarian Cancer Overview
Trends in Incidence and Mortality
Current Approaches to Treatment
Gene Therapy Research Activities
Adaptimmune Limited
Research Activities
Company Background
BioCancell Ltd.
Research Activities
Company Background
Celsion Corporation
Research Activities
Company Background
VBL Therapeutics Ltd.
Research Activities
Company Background
Market Opportunity
Current Market for Treating Ovarian Cancer
Potential Market for Gene Therapy in Ovarian Cancer
GENE THERAPY OUTLOOK IN PANCREATIC CANCER
Pancreatic Cancer Overview
Trends in Incidence and Mortality
Current Approaches to Treatment
Gene Therapy Research Activities
Advantagene, Inc.
Research Activities
Company Background
BioCancell Ltd.
Research Activities
Company Background
Market Opportunity
Current Market for Treating Pancreatic Cancer
Potential Market for Gene Therapy in Pancreatic Cancer
GENE THERAPY OUTLOOK IN PROSTATE CANCER
Prostate Cancer Overview
Trends in Incidence and Mortality
Current Approaches to Treatment
Gene Therapy Research Activities
Advantagene, Inc.
Research Activities
Company Background
Momotaro-Gene, Inc.
Research Activities
Company Background
Market Opportunity
Current Market for Treating Prostate Cancer
Potential Market for Gene Therapy in Prostate Cancer
GENE THERAPY AND OTHER CANCERS
Other Cancer Overview
Esophagus Cancer
Multiple Myeloma
Renal Cancer
Thyroid Cancer
Trends in Incidence and Mortality
Esophageal Cancer
Multiple Myeloma
Renal Cancer
Thyroid Cancer
Gene Therapy Research Activities for Other or Unspecific Cancer
Advantagene, Inc.
Research Activities
Company Background
Bluebird Bio
Research Activities
Company Background
MaxiVAX
Research Activities
Company Background
OncoSec Medical, Inc.
Research Activities
Company Background
Sevion Therapeutics, Inc.
Research Activities
Company Background
Takara Bio, Inc.
Research Activities
Company Background
VBL Therapeutics Ltd.
Research Activities
Company Background
Other Companies
GENE THERAPY IN CANCER MARKET SUMMARY AND OUTLOOK
Overview
Cancer Focus Summary
Cancer Gene Therapy Forecast Analysis
Impact of Gene Therapy on Specific Cancer Markets
INDUSTRY PARTICIPANTS AND CONTRIBUTORS

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