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  4. > SLIT Tablets, Self-Administration, and Allergy Immunotherapy to 2022 : Products, Players, Markets, and Forecasts

Immunotherapy involves the administration of gradually increasing doses of the allergen over a period of time to desensitize the patient. It is the only known treatment that modifies the immune response and treats the cause rather than the symptoms. In the United States, the only licensed route of administration is subcutaneous injection (SCIT). An alternative to SCIT is sublingual immunotherapy (SLIT). The medication is kept beneath the tongue where it is absorbed into the mucosa. Though complex and not fully characterized mechanisms, administration of allergens through the oral, gingival, or sublingual mucosa can decrease the allergic response thus desensitizing the patient by modifying disease at least temporarily if not permanently (i.e. inducing tolerance). The incidence of severe or serious AE associated with SLIT is significantly lower than with SCIT such that SLIT which may be self-administered at home, while safe use of SCIT requires administration in a clinic that is capable of responding to systemic allergic reactions.

What You Will Learn

- What approved allergy immunotherapeutics (AIT) are currently marketed, how are they administered, what are the device specifics, and who markets them?
• Who are the important AIT suppliers, their manufacturing infrastructure and locations, their capabilities?
• What are the major factors driving demand for self-administered AIT products including SLIT tablets?
• How important are manufacturer relationships and what are the key alliances in the industry?
• What are the essential factors, issues, technologies and market development issues for self-administered AIT products?
• What are the significant economic, technology, and regulatory factors affecting AIT products?

Table Of Contents

SLIT Tablets, Self-Administration, and Allergy Immunotherapy to 2022 : Products, Players, Markets, and Forecasts
Executive Summary

Allergy Immunotherapy Market Dynamics
Competitive Landscape
The Market for Allergy Immunotherapy
Allergen Market Segments
Pollen-based Allergies
Possible Effects of Air Pollution in Allergic Diseases
Dust Mites
Pet Allergies
Food Allergies
Therapeutic Market Segments
Named Patient Products
Prescription Products
Emerging Therapeutic Segments
Synthetic Peptide Epitopes
Intralymphatic (ILIT) Administration
Epicutaneous Administration
Next Generation AIT
Recombinant Allergens
Allergy Therapeutics Technology Platforms
Contiguous Overlapping Peptides (Anergis)
Sublingual Tablet Immunotherapy
SLIT Tablet Formulations
The Potential Role of Adjuvants
Approved SLIT Tablet Products
U.S.
Europe
Development-stage Sublingual Allergen Tablets
Birch
Dust Mite
Grass
Ragweed
Market Data and Forecasts
Market Factors
Regulatory Factors and Issues
United States
Europe
Japan
The Shift from Named Patient to Prescription-based Marketing
The Market Impact on OTC Rhinitis Treatment Products
Clinical Trials and Product Development
Managed Care and Healthcare Economics
Company Profiles

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