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DE-102 (Macular Edema and Macular Degeneration) - Forecast and Market Analysis to 2023

  • October 2014
  • -
  • GlobalData
  • -
  • 108 pages

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DE-102 (Macular Edema and Macular Degeneration) - Forecast and Market Analysis to 2023

Summary

Macular Edema is a condition where fluid accumulates on the macula, leading to vision impairment or in severe cases even vision loss. The three main types of ME are diabetic macular edema (DME), and macular edema following either a central or branch retinal vein occlusion (ME-CRVO and ME-BRVO). Age-related macular degeneration (AMD) is a painless eye condition which leads to gradual, irreversible, loss of central vision, and is one of the leading causes of blindness among people aged 50 and over in the developed world. Currently the ME and AMD markets are dominated by the use of anti-VEGF monotherapy, however, in recent years, corticosteroid implants have been reaching the ME market which could challenge the stronghold these drugs have in this sector. The AMD market will see the arrival of the first therapies to treat dry AMD, fulfilling a huge unmet need in the management of this retinal disease, and these first-in-class therapies will strongly drive the market growth over the next ten years. The launch of wet AMD adjunctive therapies will also see a significant change in the treatment of AMD patients and have a positive impact on the market growth.

Santen Pharmaceutical’s pipeline candidate, DE-102 (betamethasone), is a steroid microsphere drug undergoing Phase II/III studies in Japan for the treatment of DME and ME-BRVO. Betamethasone is a potent steroid of the glucocorticoid class, with both anti-inflammatory and immunosuppressive properties. In preclinical studies, DE-102 demonstrated sustained efficacy when injected around the affected area, prompting Santen to develop the drug using a new delivery technology.

Scope

- Overview of Macular Edema and Macular Degeneration, including epidemiology, etiology, symptoms, diagnosis, pathology and treatment guidelines as well as an overview on the competitive landscape.
- Detailed information on DE-102 including product description, safety and efficacy profiles as well as a SWOT analysis.
- Sales forecast for DE-102 for the top country from 2013 to 2023.
- Sales information covered for Japan

Reasons to buy

- Understand and capitalize by identifying products that are most likely to ensure a robust return.
- Stay ahead of the competition by understanding the changing competitive landscape for Macular Edema and Macular Degeneration.
- Effectively plan your M&A and partnership strategies by identifying drugs with the most promising sales potential.
- Make more informed business decisions from insightful and in-depth analysis of DE-102 performance.
- Obtain sales forecast for DE-102 from 2013-2023 in top country (Japan).

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