1. Market Research
  2. > Healthcare
  3. > Pathology Market Trends
  4. > Lotronex (Irritable Bowel Syndrome) - Forecast and Market Analysis to 2023

Lotronex (Irritable Bowel Syndrome) - Forecast and Market Analysis to 2023

Summary

Irritable Bowel Syndrome (IBS) is a common disorder characterized by abdominal discomfort associated with altered bowel function. Although IBS is not a life-threatening disorder, it has a considerable effect on patients’ quality of life (QOL). In terms of volume, the IBS market is a large, albeit naïve, one, with only a small number of pharmacotherapies indicated for the treatment of the disorder, and it is also characterized by significant unmet needs.

Lotronex (alosetron) is indicated for women with severe IBS-D who have chronic IBS, have had anatomic or biochemical abnormalities of the GI tract excluded, and have not responded adequately to conventional therapy. GlaxoSmithKline (GSK) initially introduced this product into the US market in February 2000. However, a few months later, in November 2000, the company decided to withdraw the drug due to it being linked with undesirable adverse effects, such as ischemic colitis (restricted blood flow to the colon), severe constipation, and three fatalities.

Scope

- Overview of IBS, including epidemiology, etiology, symptoms, diagnosis, pathology and treatment guidelines as well as an overview on the competitive landscape.
- Detailed information on Lotronex including product description, safety and efficacy profiles as well as a SWOT analysis.
- Sales forecast for Lotronex for the top country from 2013 to 2023.
- Sales information covered for the US.

Reasons to buy

- Understand and capitalize by identifying products that are most likely to ensure a robust return.
- Stay ahead of the competition by understanding the changing competitive landscape for IBS.
- Effectively plan your M&A and partnership strategies by identifying drugs with the most promising sales potential.
- Make more informed business decisions from insightful and in-depth analysis of Lotronex performance.
- Obtain sales forecast for Lotronex from 2013-2023 in top country (the US).

Table Of Contents

Lotronex (Irritable Bowel Syndrome) - Forecast and Market Analysis to 2023
1 Table of Contents
2 Introduction 8
2.1 Catalyst 8
2.2 Related Reports 8
3 Disease Overview 10
3.1 Etiology and Pathophysiology 10
3.1.1 Etiology 10
3.1.2 Pathophysiology 11
3.2 Classification 11
3.3 Symptoms 12
3.4 Prognosis 13
3.5 Quality of Life 13
4 Disease Management 14
4.1 Diagnosis and Treatment Overview 14
4.1.1 Diagnosis 14
4.1.2 Treatment Guidelines and Leading Prescribed Drugs 16
4.1.3 Clinical Practice 19
5 Competitive Assessment 21
5.1 Overview 21
6 Lotronex (alosetron) 23
6.1 Overview 23
6.2 Efficacy 24
6.3 Safety 25
6.4 SWOT Analysis 27
6.5 Forecast 27
7 Appendix 29
7.1 Bibliography 29
7.2 Abbreviations 31
7.3 Methodology 33
7.4 Forecasting Methodology 33
7.4.1 Diagnosed IBS Patients 33
7.4.2 General Pricing Assumptions 34
7.4.3 Individual Drug Assumptions 35
7.4.4 Generic Erosion 35
7.5 Primary Research - KOLs Interviewed for This Report 36
7.6 Primary Research - Prescriber Survey 38
7.7 About the Authors 39
7.7.1 Analyst 39
7.7.2 Therapy Area Director 39
7.7.3 Global Head of Healthcare 40
7.8 About GlobalData 41
7.9 Disclaimer 41

1.1 List of Tables

Table 1: Common Symptoms of IBS 12
Table 2: Summary of the Various Diagnostic Criteria Used for the Diagnosis of IBS 15
Table 3: Treatment Guidelines for IBS 17
Table 4: Leading Prescribed Drugs for IBS by Predominant Symptoms in the 7MM, 2014† 18
Table 5: Leading Branded Treatments for IBS, 2014 22
Table 6: Product Profile - Lotronex 24
Table 7: Safety of Lotronex - Most Frequently Reported Adverse Events 26
Table 8: Lotronex SWOT Analysis, 2014 27
Table 9: Global IBS Sales Forecasts ($m) for Lotronex, 2013-2023 28
Table 10: High-Prescribing Physicians (Non-KOLs) Surveyed, by Country 38

1.2 List of Figures

Figure 1: Summary of Pharmacotherapies Used to Treat IBS 20

View This Report »

Get Industry Insights. Simply.

  • Latest reports & slideshows with insights from top research analysts
  • 24 Million searchable statistics with tables, figures & datasets
  • More than 10,000 trusted sources
24/7 Customer Support

Talk to Veronica

+1 718 514 2762

Purchase Reports From Reputable Market Research Publishers
Liver Cirrhosis- Market Insights, Epidemiology and Market Forecast-2023

Liver Cirrhosis- Market Insights, Epidemiology and Market Forecast-2023

  • $ 4950
  • Industry report
  • November 2016
  • by Delve Insight

Note*: This report requires 5 business days to complete. DelveInsight’s Liver Cirrhosis - Market Insights, Epidemiology and Market Forecast-2023” Reports provides an overview of the disease and global ...

Peptic Ulcer  - Market Insights, Epidemiology and Market Forecast-2023

Peptic Ulcer  - Market Insights, Epidemiology and Market Forecast-2023

  • $ 4950
  • Industry report
  • November 2016
  • by Delve Insight

Note*: This report requires 5 business days to complete. DelveInsight’s Peptic Ulcer - Market Insights, Epidemiology and Market Forecast-2023” Reports provides an overview of the disease and global ...

Crohn’s disease (CD)- Market Insights, Epidemiology and Market Forecast-2023

Crohn’s disease (CD)- Market Insights, Epidemiology and Market Forecast-2023

  • $ 4950
  • Industry report
  • November 2016
  • by Delve Insight

Note*: This report requires 5 business days to complete. DelveInsight’s Crohn’s disease (CD) - Market Insights, Epidemiology and Market Forecast-2023” Reports provides an overview of the disease ...


ref:plp2014

Reportlinker.com © Copyright 2016. All rights reserved.

ReportLinker simplifies how Analysts and Decision Makers get industry data for their business.