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Key Material Technologies for Next Generation Implants : Material Innovations Driving the Adoption of Medical Implants

  • March 2015
  • 45 pages
  • Frost & Sullivan
Report ID: 2838382

Summary

Table of Contents

Research Scope

With the rise of lifestyle diseases and aging population, there has been an increasing occurrence of lifestyle diseases. Also, increasing awareness of health related issues and improved access to healthcare, the medical devices industry is in an expanding curve. The medical implants market is driven by an increase in health needs of ageing population, sedentary lifestyle, improving trauma care, and advancement in medical technologies.
According to a WHO (World Health Organization) statistics, there are more than million people in the world above the age of , out of which million are from developing countries. This can increase the demand for orthopedic, cardiovascular, ophthalmic and orthodontic implants. However, high cost of treatment and proportional increase in failure of implants and increasing rejection rates are major challenges faced by the industry. This scenario signifies the importance of materials that are used for manufacturing the implants.
Hence, this research service’s prime focus would be on various types of materials that are used for implants

This research service will cover the following key points related to materials for implants:

•Technology overview, technology capability, and value chain analysis of materials used for implants.
•Industry trends and assessment of emerging innovations and their market significance to stakeholders.
•Key market drivers and challenges that will impact large-scale adoption of materials for implants.
•Demand side analysis of implant materials focusing on end consumer needs.
•Emerging opportunities in the field of implant materials and their evaluation.
•Key patents–both granted and in the application status–related to materials for implants.
•Contacts of key stakeholders in the industry.

Key Findings

Despite the implant market being considered as stable, increasing patient needs, end-user demands and stringent regulatory approvals are pushing for continuous research and development of materials for better biocompatibility and enhanced healing and clinical outcomes.
Implant materials innovations is more prominent in the North American region. Diverse developments will also be seen in Europe after North America. The Asia Pacific countries may not see much significant growth in terms of technology development as US or European countries; but developments in Japan and China will contribute significantly to the rise of the technology. Nevertheless, in the future, there is huge market potential for these technologies developed in North America and Europe in the APAC region.
Stakeholder initiatives, especially collaborations will take a major step in the advancement of material technologies. Across globe, technology advancements from research institutes, academia and medical device manufacturers help in increasing the adoption of innovative materials.
Advances in engineering of the material, chemistry, composition, and micro structure are expected to maintain the demand for ceramics and bioceramics in implants with superior wear characteristics and long-term utility of implants.
Acceptance and use of bioresorbable materials for implants will increase as further research and clinical studies establish their safety, efficacy, and proper usage. Bioresorbable technology is expected to be game changer for implants that require high load bearing properties. Bioresorbable polymers are also being looked into as carriers for osteoconductive compounds.

Importance of Materials Technology for Implants

Biomaterials within the implant market are considered as key enabling technologies that used for corrective procedures, treat deformities. The biomaterials used for implants augment the treatment and promote fusion for enabling/accelerating/substituting the human body's natural healing process.
There is vigorous research and development on biomaterials for implants conducted by diverse companies within engineering, chemicals, material sciences, polymers, tissue engineering, biologics, and even medicine. The industry uses varied materials such as polymers, metals, alloys, ceramics, composites, scaffolds, and biological materials with specific properties and biological interactions.
The major requirements that developers requires when it comes to biomaterials is clinical, manufacturing, and economical. Clinical means appropriate mechanical strength and biocompatibility, manufacturing refers to fabrication of the biomaterials for optimum implant design while economic refers to the cost requirements.
A key deterrent is the regulatory policies as quite a number of post implantation issues, recalls have resulted in regulatory warnings. Implant manufacturers need to be clearly aware of the scientific intricacies involved with introducing new materials in the human body.
Lack of data for long-term performance of clinical studies and dicey reimbursement policies are other challenges that are present in the implants market.

Key Requirements of an Implant Material

Biocompatibility : The implant material needs to have long-term compatibility or zero interference with body fluids and tissues. The coating should further not produce byproducts that are toxic to the human system or that could possibly interfere with the implant itself.

Inertness : The material used is required to be inert to prevent the contamination of the implant through gassing and other reactions.

Paintability : The material should offer good coverage for protective coatings without bridging or pooling, especially while coating implants with complex geometries and sizes.

Sterilization / Resistance : The sterilization process of implants involves exposure to high temperatures, chemicals, and radiations. The coatings therefore require significant resistance to sterilization conditions.

Resistance to Flaking : The material is required to show strong adherence to the substrate and prevent flaking of the protective coating or the substrate itself.

Thickness : Implants require varying levels of thickness; for instance, some applications require thin material thickness without compromising the required physical, chemical, electrical, and biological properties.

Curing : The cure forces of a material must not degrade or distort the implant even when coated and maintain its structural integrity.

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