1 Table of contents
I Table of contents 3
I. 1 List of Data tables 6
I. 2 List of Charts 7
II Introduction and Overview 8
II. 1 GlobalData Report Guidance 8
3 Disease Data 9
III. 1 Disease Data : Parkinson’s Disease 9
III. 1.1 Introduction 9
III. 1.2 Etiology 9
III. 1.3 Signs and Symptoms 10
III. 1.4 Pathophysiology 10
III. 1.5 Treatment 11
III. 1.6 Epidemiology 11
III. 2 Disease Data : Chronic Pain 11
III. 2.1 Introduction 11
III. 2.2 Etiology 12
III. 2.3 Signs and Symptoms 12
III. 2.4 Pathophysiology 12
III. 2.5 Treatment 12
III. 2.6 Epidemiology 13
III. 3 Disease Data : Epilepsy 13
III. 3.1 Introduction 13
III. 3.2 Etiology 14
III. 3.3 Signs and Symptoms 14
III. 3.4 Pathophysiology 14
III. 3.5 Treatment 15
III. 3.6 Epidemiology 15
IV Neurostimulation Device Based Treatment Overview 16
IV. 1 Neurostimulation Devices: Technology Overview 16
IV. 1.1 Introduction 16
IV. 1.2 Advantages and Disadvantages of Neurostimulation Therapy 17
IV. 1.3 Types of Neurostimulators 17
5 World Neurostimulation Devices March ket: World March ket Characterization 19
V. 1 World Neurostimulation Devices March ket, Sales s($m), 2002 ? 2009 19
V. 2 World Neurostimulation Devices March ket, Sales s($m), 2009 ? 2016 20
V. 3 Neurostimulation Devices: Key March ket Trends 21
V. 4 Neurostimulation Devices: March ket Dynamics 21
V. 4.1 March ket Drivers 21
V. 4.2 March ket Restraints 23
V. 5 Neurostimulation Devices: Key Opportunities and Unmet Needs 23
V. 5.1 Opportunities 23
V. 5.2 Unmet Need 24
6 World Neurostimulation Devices March ket: Segment Wise Analysis 25
VI. 1 Deep Brain Stimulation Devices March ket: March ket Characterization 25
VI. 1.1 Deep Brain Stimulation Devices March ket, Sales s (USD Million), 2002 ? 2009 25
VI. 1.2 Deep Brain Stimulation Devices March ket, Sales s (USD Million), 2009 ? 2016 26
VI. 2 Spinal Cord Stimulation Devices March ket: March ket Characterization 27
VI. 2.1 Spinal Cord Stimulation Devices March ket, Sales s (USD Million), 2002 ? 2009 27
VI. 2.2 Spinal Cord Stimulation Devices March ket, Sales s (USD Million), 2009 ? 2016 28
VI. 3 Vagus Nerve Stimulation Devices March ket: March ket Characterization 29
VI. 3.1 Vagus Nerve Stimulation Devices March ket, Sales s (USD Million), 2002 ? 2009 29
VI. 3.2 Vagus Nerve Stimulation Devices March ket, Sales s (USD Million), 2009 ? 2016 30
7 World Neurostimulation Devices March ket: Country Wise March ket Analysis and Forecasted data s 31
VII. 1 World Neurostimulation Devices March ket: Cross-Country March ket Analysis and Forecasted data s 31
VII. 1.1 Cross-Country Analysis of Neurostimulation Devices industry, 2009 31
VII. 2 Sales s and Forecasted data s, By Country 32
VII. 2.1 US Neurostimulation Devices March ket, Sales s (USD Million), By Segment, 2002 – 2009 32
VII. 2.2 US Neurostimulation Devices March ket, Sales s (USD Million), By Segment, 2009 – 2016 33
VII. 2.3 Canada Neurostimulation Devices March ket, Sales s (USD Million), By Segment, 2002 – 2009 34
VII. 2.4 Canada Neurostimulation Devices March ket, Sales s (USD Million), By Segment, 2009 – 2016 35
VII. 2.5 UK Neurostimulation Devices March ket, Sales s (USD Million), By Segment, 2002 – 2009 36
VII. 2.6 UK Neurostimulation Devices March ket, Sales s (USD Million), By Segment, 2009 – 2016 37
VII. 2.7 Germany Neurostimulation Devices March ket, Sales s (USD Million), By Segment, 2002 – 2009 38
VII. 2.8 Germany Neurostimulation Devices March ket, Sales s (USD Million), By Segment, 2009 – 2016 39
VII. 2.9 France Neurostimulation Devices March ket, Sales s (USD Million), By Segment, 2002 – 2009 40
VII. 2.10 France Neurostimulation Devices March ket, Sales s (USD Million), By Segment, 2009 – 2016 41
VII. 2.11 Italy Neurostimulation Devices March ket, Sales s (USD Million), By Segment, 2002 – 2009 42
VII. 2.12 Italy Neurostimulation Devices March ket, Sales s (USD Million), By Segment, 2009 – 2016 43
VII. 2.13 Spain Neurostimulation Devices March ket, Sales s (USD Million), By Segment, 2002 – 2009 44
VII. 2.14 Spain Neurostimulation Devices March ket, Sales s (USD Million), By Segment, 2009 – 2016 45
VII. 2.15 Japan Neurostimulation Devices March ket, Sales s (USD Million), By Segment, 2002 – 2009 46
VII. 2.16 Japan Neurostimulation Devices March ket, Sales s (USD Million), By Segment, 2009 – 2016 47
VII. 2.17 China Neurostimulation Devices March ket, Sales s (USD Million), By Segment, 2002 – 2009 48
VII. 2.18 China Neurostimulation Devices March ket, Sales s (USD Million), By Segment, 2009 – 2016 49
VII. 2.19 India Neurostimulation Devices March ket, Sales s (USD Million), By Segment, 2002 – 2009 50
VII. 2.20 India Neurostimulation Devices March ket, Sales s (USD Million), By Segment, 2009 – 2016 51
VII. 2.21 Australia Neurostimulation Devices March ket, Sales s (USD Million), By Segment, 2002 ? 2009 52
VII. 2.22 Australia Neurostimulation Devices March ket, Sales s (USD Million), By Segment, 2009 – 2016 53
VII. 2.23 Brazil Neurostimulation Devices March ket, Sales s (USD Million), By Segment, 2002 – 2009 54
VII. 2.24 Brazil Neurostimulation Devices March ket, Sales s (USD Million), By Segment, 2009 – 2016 55
8 World Neurostimulation Devices March ket: Competitive Assessment 56
VIII. 1 World Neurostimulation Devices March ket, Key Market Shares s (%), 2009 56
VIII. 2 Medtronic, Inc 57
VIII. 2.1 Overview 57
VIII. 2.2 Neurostimulation Devices Portfolio 57
VIII. 3 St. Jude Medical, Inc 57
VIII. 3.1 Overview 57
VIII. 3.2 Neurostimulation Devices Portfolio 57
VIII. 4 Boston Scientific Corporation 58
VIII. 4.1 Overview 58
VIII. 4.2 Neurostimulation Devices Portfolio 58
VIII. 5 Cyberonics, Inc 58
VIII. 5.1 Overview 58
VIII. 5.2 Neurostimulation Devices Portfolio 58
9 World Neurostimulation Devices March ket: Key March keted Products 59
IX. 1 Medtronic, Inc: Activa RC 59
IX. 1.1 Product Description 59
IX. 1.2 Features and Benefits 59
IX. 2 Medtronic, Inc: RestoreUltra 59
IX. 2.1 Product Description 59
IX. 2.2 Features and Benefits 59
IX. 3 St. Jude’s Medical, Inc: Eon Mini 59
IX. 3.1 Product Description 59
IX. 3.2 Features and Benefits 59
IX. 4 Boston Scientific Corporation: Precision Plus 60
IX. 4.1 Product Description 60
IX. 4.2 Features and Benefits 60
IX. 5 Cyberonics, Inc: VNS Therapy 60
IX. 5.1 Product Description 60
IX. 5.2 Features and Benefits 60
X Global Neurostimulation Devices March ket: Strategic Pipeline Assessment 61
X. 1 Neurostimulation Devices: List of Pipeline Products 61
X. 2 Pipeline Products Assessment for Neurostimulation Devices by Sector, Global, 2010 64
X. 3 Neurostimulation Devices: Profiles of Pipeline Products Under Clinical Development 65
X. 3.1 Cyberonics, Inc: 3T MRI Safe Lead 65
X. 3.2 Boston Scientific Corporation: Bion Microstimulator System for chronic headache 65
X. 3.3 Brainsway, Inc: Deep TMS H System 65
X. 3.4 Intelect Medical, Inc: Enspire DBS Therapy System for Stroke 65
X. 3.5 Magstim Firms Limited: Magstim eldith DC Stimulator plus 65
X. 3.6 DynaMed Systems, LLC: Traxon 66
XI Global Neurostimulation Devices March ket: Merger and Acquisition Landscape 67
XI. 1 World Neurostimulation Devices March ket: Deals Overview 67
XI. 2 World Neurostimulation Devices March ket: Key Acquisitions 68
XI. 2.1 St. Jude Medical Takes Over Northstar Neuroscience 69
XI. 2.2 Greatbatch Takes Over Quan Emerteq 69
XI. 2.3 Greatbatch Takes Over Enpath Medical 70
XII Appendix 71
XII. 1 Definitions 71
XII. 2 Acronyms 71
XII. 3 Information Sources 73
XII. 4 Research Methodology 73
XII. 5 Secondary Research 74
XII. 6 Primary Research 75
XII. 7 Models 75
XII. 8 Forecasted data s 75
XII. 9 Expert Panels 75
XII. 10 GlobalData Consulting 76
XII. 11 Contact Us 76
XII. 12 Disclaimer 76
1.1 List of Data tables
Data table 1: Neurostimulation Devices March ket, Global, Sales s (USD Million), 2002 ? 2009 19
Data table 2: Neurostimulation Devices March ket, Global, Sales s (USD Million), 2009 ? 2016 20
Data table 3: Deep Brain Stimulation Devices March ket, Global, Sales s (USD Million), 2002 ? 2009 25
Data table 4: Deep Brain Stimulation Devices March ket, Global, Sales s (USD Million), 2009 ? 2016 26
Data table 5: Spinal Cord Stimulation Devices March ket, Global, Sales s (USD Million), 2002 ? 2009 27
Data table 6: Spinal Cord Stimulation Devices March ket, Global, Sales s (USD Million), 2009 ? 2016 28
Data table 7: Vagus Nerve Stimulation Devices March ket, Global, Sales s (USD Million), 2002 ? 2009 29
Data table 8: Vagus Nerve Stimulation Devices March ket, Global, Sales s (USD Million), 2009 ? 2016 30
Data table 9: Neurostimulation Devices March ket, Global, March ket Analysis by Countries, 2002 ? 2016 31
Data table 10: Neurostimulation Devices March ket, US, Sales s (USD Million), By Segment, 2002 – 2009 32
Data table 11: Neurostimulation Devices March ket, US, Sales s (USD Million), By Segment, 2009 – 2016 33
Data table 12: Neurostimulation Devices March ket, Canada, Sales s (USD Million), By Segment, 2002 – 2009 34
Data table 13: Neurostimulation Devices March ket, Canada, Sales s (USD Million), By Segment, 2009 – 2016 35
Data table 14: Neurostimulation Devices March ket, UK, Sales s (USD Million), By Segment, 2002 – 2009 36
Data table 15: Neurostimulation Devices March ket, UK, Sales s (USD Million), By Segment, 2009 – 2016 37
Data table 16: Neurostimulation Devices March ket, Germany, Sales s (USD Million), By Segment, 2002 – 2009 38
Data table 17: Neurostimulation Devices March ket, Germany, Sales s (USD Million), By Segment, 2009 – 2016 39
Data table 18: Neurostimulation Devices March ket, France, Sales s (USD Million), By Segment, 2002 – 2009 40
Data table 19: Neurostimulation Devices March ket, France, Sales s (USD Million), By Segment, 2009 – 2016 41
Data table 20: Neurostimulation Devices March ket, Italy, Sales s (USD Million), By Segment, 2002 – 2009 42
Data table 21: Neurostimulation Devices March ket, Italy, Sales s (USD Million), By Segment, 2009 – 2016 43
Data table 22: Neurostimulation Devices March ket, Spain, Sales s (USD Million), By Segment, 2002 – 2009 44
Data table 23: Neurostimulation Devices March ket, Spain, Sales s (USD Million), By Segment, 2009 – 2016 45
Data table 24: Neurostimulation Devices March ket, Japan, Sales s (USD Million), By Segment, 2002 – 2009 46
Data table 25: Neurostimulation Devices March ket, Japan, Sales s (USD Million), By Segment, 2009 – 2016 47
Data table 26: Neurostimulation Devices March ket, China, Sales s (USD Million), By Segment, 2002 – 2009 48
Data table 27: Neurostimulation Devices March ket, China, Sales s (USD Million), By Segment, 2009 – 2016 49
Data table 28: Neurostimulation Devices March ket, India, Sales s (USD Million), By Segment, 2002 – 2009 50
Data table 29: Neurostimulation Devices March ket, India, Sales s (USD Million), By Segment, 2009 – 2016 51
Data table 30: Neurostimulation Devices March ket, Australia, Sales s (USD Million), By Segment, 2002 ? 2009 52
Data table 31: Neurostimulation Devices March ket, Australia, Sales s (USD Million), By Segment, 2009 – 2016 53
Data table 32: Neurostimulation Devices March ket, Brazil, Sales s (USD Million), By Segment, 2002 – 2009 54
Data table 33: Neurostimulation Devices March ket, Brazil, Sales s (USD Million), By Segment, 2009 – 2016 55
Data table 34: Neurostimulation Devices March ket, Global, Key Market Shares s (USD Million), 2009 56
Data table 35: Medtronic, Inc., Key March keted Products, Neurostimulation Devices Category 57
Data table 36: St. Jude Medical, Inc. Key March keted Products, Neurostimulation Devices Category 57
Data table 37: Boston Scientific Corp., Key March keted Products, Neurostimulation Devices Category 58
Data table 38: Cyberonics, Inc, Key March keted Products, Neurostimulation Devices Category 58
Data table 39: Activa RC Deep Brain Neurostimulator, Features and Benefits 59
Data table 40: RestoreUltra Spinal Cord Neurostimulator, Features and Benefits 59
Data table 41: Eon Mini Spinal Cord Stimulator, Features and Benefits 59
Data table 42: Precision Plus Spinal Cord Stimulator, Features and Benefits 60
Data table 43: VNS Therapy Features and Benefits 60
Data table 44: Neurostimulation Devices, Pipeline Products, 2010, Table 1 61
Data table 45: Neurostimulation Devices, Pipeline Products, 2010, Table 2 62
Data table 46: Neurostimulation Devices, Pipeline Products, 2010, Table 3 63
Data table 47: Neurostimulation Devices March ket, Global, Deals Overview, 2005 ? 2009 67
Data table 48: Neurostimulation Devices March ket, Global, Merger and Acquisition Deal Value (USD Million), 2005 ? 2009 68
Data table 49: Neurostimulation Devices Market, Global, List of Merger and Acquisition Deals, 2004 ? 2010 69
1.2 List of Charts
Chart 1: Neurostimulation Therapy, FDA Year of Approval 17
Chart 2: Neurostimulation Devices March ket, Global, Sales s (USD Million), 2002 ? 2009 19
Chart 3: Neurostimulation Devices March ket, Global, Sales s (USD Million), 2009 ? 2016 20
Chart 4: Potential of Neurostimulation Devices for the Treatment of Various Indications, 2010 21
Chart 5: Deep Brain Stimulation Devices March ket, Global, Sales s (USD Million), 2002 ? 2009 25
Chart 6: Deep Brain Stimulation Devices March ket, Global, Sales s (USD Million), 2009 ? 2016 26
Chart 7: Spinal Cord Stimulation Devices March ket, Global, Sales s (USD Million), 2002 ? 2009 27
Chart 8: Spinal Cord Stimulation Devices March ket, Global, Sales s (USD Million), 2009 ? 2016 28
Chart 9: Vagus Nerve Stimulation Devices March ket, Global, Sales s (USD Million), 2002 ? 2009 29
Chart 10: Vagus Nerve Stimulation Devices March ket, Global, Sales s (USD Million), 20016 30
Chart 11: Neurostimulation Devices March ket, Global, March ket Analysis by Countries, 2002 ? 2016 31
Chart 12: Neurostimulation Devices March ket, US, Sales s (USD Million), By Segment, 2002 – 2009 32
Chart 13: Neurostimulation Devices March ket, US, Sales s (USD Million), By Segment, 2009 – 2016 33
Chart 14: Neurostimulation Devices March ket, Canada, Sales s (USD Million), By Segment, 2002 – 2009 34
Chart 15: Neurostimulation Devices March ket, Canada, Sales s (USD Million), By Segment, 2009 – 2016 35
Chart 16: Neurostimulation Devices March ket, UK Sales s (USD Million), By Segment, 2002 – 2009 36
Chart 17: Neurostimulation Devices March ket, UK, Sales s (USD Million), By Segment, 2009 – 2016 37
Chart 18: Neurostimulation Devices March ket, Germany, Sales s (USD Million), By Segment, 2002 – 2009 38
Chart 19: Neurostimulation Devices March ket, Germany, Sales s (USD Million), By Segment, 2009 – 2016 39
Chart 20: Neurostimulation Devices March ket, France, Sales s (USD Million), By Segment, 2002 – 2009 40
Chart 21: Neurostimulation Devices March ket, France, Sales s (USD Million), By Segment, 2009 – 2016 41
Chart 22 Neurostimulation Devices March ket, Italy, Sales s (USD Million), By Segment, 2002 – 2009 42
Chart 23: Neurostimulation Devices March ket, Italy, Sales s (USD Million), By Segment, 2009 – 2016 43
Chart 24: Neurostimulation Devices March ket, Spain, Sales s (USD Million), By Segment, 2002 – 2009 44
Chart 25: Neurostimulation Devices March ket, Spain, Sales s (USD Million), By Segment, 2009 – 2016 45
Chart 26: Neurostimulation Devices March ket, Japan, Sales s (USD Million), By Segment, 2002 – 2009 46
Chart 27: Neurostimulation Devices March ket, Japan, Sales s (USD Million), By Segment, 2009 – 2016 47
Chart 28: Neurostimulation Devices March ket, China, Sales s (USD Million), By Segment, 2002 – 2009 48
Chart 29: Neurostimulation Devices March ket, China, Sales s (USD Million), By Segment, 2009 – 2016 49
Chart 30: Neurostimulation Devices March ket, India, Sales s (USD Million), By Segment, 2002 – 2009 50
Chart 31: Neurostimulation Devices March ket, India, Sales s (USD Million), By Segment, 2009 – 2016 51
Chart 32: Neurostimulation Devices March ket, Australia, Sales s (USD Million), By Segment, 2002 ? 2009 52
Chart 33: Neurostimulation Devices March ket, Australia. Sales s (USD Million), By Segment, 2009 – 2016 53
Chart 34: Neurostimulation Devices March ket, Brazil, Sales s (USD Million), By Segment, 2002 ? 2016 54
Chart 35: Neurostimulation Devices March ket, Brazil, Sales s (USD Million), By Segment, 2009 – 2016 55
Chart 36: : Neurostimulation Devices March ket, Global, Key Market Shares s (%), 2009 56
Chart 37: Pipeline Product Assessment for Neurostimulation Devices by Sector, World 64
Chart 38: Neurostimulation Devices March ket, Global, Deals Overview, 2005 ? 2009 67
Chart 39: Neurostimulation Devices March ket, Global, Merger and Acquisition Deal Value (USD Million), 2005 ? 2009 68
Chart 40: GlobalData Methodology 74
Companies mentioned
Medtronic, Inc
St. Jude Medical, Inc
Boston Scientific Corporation
Cyberonics, Inc