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  4. > 2015 Strategies in the European Nucleic Acid Testing Market

2015 Strategies in the European Nucleic Acid Testing Market

  • May 2015
  • -
  • Venture Planning Group
  • -
  • 1273 pages

This comprehensive five-country report is designed to help current suppliers and potential market entrants identify and evaluate major business opportunities emerging in the molecular diagnostics market during the next five years. The report explores business and technological trends in major European countries (France, Germany, Italy, Spain, UK); provides 5-year test volume/sales forecasts; estimates shares of leading competitors; compares features of major analyzers; profiles leading market players; and identifies specific product and business opportunities facing instrument and consumable suppliers during the next five years.

The $4.5 billion molecular diagnostics market is unquestionably the most rapidly growing segment of the in vitro diagnostics industry. The next five years will witness significant developments in reagent systems and automation, as well as introduction of a wide range of new products that will require innovative marketing approaches. The rate of market penetration into routine clinical laboratories, however, will depend on the introduction of cost-effective and automated systems with amplification methods.

In order to successfully capitalize on the opportunities presented by the molecular diagnostics market, many companies are already exploiting new technologies as corporate strategic assets, managed in support of business and marketing strategies. Integrating new technology planning with business and corporate strategies will be one of the most challenging tasks for diagnostics companies during the next five years.  

Contains 1,273 pages and 139 tables         

Table Of Contents

2015 Strategies in the European Nucleic Acid Testing Market
Table of Contents


I. Introduction
II. Major Product Development Opportunities
A. Instrumentation
B. Reagent Kits and Test Systems/panels
C. Computers, Software and Automation
D. Auxiliary Products
III. Design Criteria for Decentralized Testing Products
IV. Alternative Market Penetration Strategies
A. Internal Development
B. Collaborative Arrangements
C. University Contracts
D. Distribution Strategies For Decentralized Testing Markets
V. Potential Market Entry Barriers and Risks
A. Market Maturity
B. Cost Containment
C. Competition
D. Technological Edge And Limitations
E. Patent Protection
F. Regulatory Constraints
G. Decentralized Testing Market Challenges
VI. Worldwide Market and Technology Review
A. DNA Sequencing
1. Introduction
2. Sequencing Methods
3. Autoradiography
4. The Human Genome Project
5. Sequencing Automation
6. Image Scanners
7. Fluorescent Detection
8. Gene Profiling
9. Gene Expression
10. Polymorphism Screening
11. Protein Interaction Networks
B. DNA and RNA Probe Technologies
1. Basic Principles
2. Probe Preparation
3. The DNA Probe Test
4. Test Formats
5. Labeling Techniques
6. Amplification Methods
C. Detection Technologies
1. Radioactive Methods
a. Overview
b. Major Isotopes
O P-32
O S-35
O H-3
O I-125
2. Non-Isotopic Methods
a. Enzymatic Labels
b. Chemical Labeling
O Indirect Chemical Labeling
O Direct Chemical Labeling
c. Fluorescence
d. Chemiluminescence
e. Electrical Conductivity
D. Molecular Diagnostic Instrumentation Review
1. Abbott LCx
2. Beckman Coulter/Biomek FK
3. BD Viper System with XTR Technology
4. BD Innova
5. Becton Dickinson SDA
6. bioMerieux NucliSENS easyMAG
7. bioMerieux NucliSENS easyQ and MiniMAG
8. Bio-Rad GeneScope
9. Cepheid GeneXpert
10. Curetis Unyvero
11. GenMark Dx eSensor XT-8
12. Hologic/Gen-Probe Panther
13. Hologic/Gen-Probe Tigris/DTS
14. HTG Molecular Edge
15. Life Technologies QuantStudio Dx
16. Qiagen QIAsymphony RGQ
17. Roche Cobas Amplicor
18. Roche Cobas TaqMan 48
19. Roche Cobas TaqMan
20. Roche Cobas TaqMan AmpliPrep
21. Roche LighCycler 480
22. Roche Cobas 4800
23. Roche Cobas s 201
24. Siemens Versant
25. Tecan LS Series
E. Biochips: Genosensors, Microarrays, and Labs-on-the-Chip
- Liquid Transportation and Mixing
- Separation
- Reaction
- Detection
F. Pharmacogenomics
G. Major Applications
1. Microbiology/Infectious Diseases
a. Overview
b. Major Infectious Diseases
° AIDS: HIV/HIV-1/2/Combo, HIVAg/HIV NAT,
Western Blot, HTLV-I/II
° Adenovirus
° Aeromonas
° Anthrax/Bacillus Anthracis
° Arboviruses
° Babesiosis
° Bacillary Epithelioid Angiomatosis (BEA)
and Other Bartonella (Rochalimaea)
° Blastocystis Hominis
° Brucella
° Campylobacter
° Candida
° Chagas Disease
° Chancroid
° Chlamydia
° Clostridium Difficile
° Coronaviruses
° Coxsackieviruses
° Creutzfeldt-Jakob's Disease
° Cryptosporidium Parvum
° Cyclospora Cayetanensis
° Cytomegalovirus
° Ebola Virus
° E. Coli
° EchoVirus
° Encephalitis
° Enteroviruses
° Epstein-Barr Virus
° Giardia Lamblia
° Gonorrhea
° Granuloma Inguinale
° Hantavirus
° Helicobacter Pylori
° Hepatitis: HAV NAT, HBV NAT, HBs Ag, HCV, HCV NAT,
Anti-HBc, Anti-HBs, Anti-HAV, Hepatitis Delta, HBc Ag,
HBe Ag, ALT/SGPT
° Herpes Simplex Virus
° Human Herpes Virus-6 (HHV-6)
° Influenza Viruses
° Legionella
° Lyme Disease
° Lymphogranuloma Venereum (LGV)
° Malaria
° Measles (Rubeola)
° Meningitis
° Microsporidium
° Mononucleosis
° Mumps
° Mycoplasma
° Papillomaviruses
° Parvovirus B19
° Pneumonia
° Polyomaviruses
° Pseudomonas Aeruginosa
° Rabies
° Respiratory Syncytial Virus (RSV)
° Rhinoviruses
° Rotavirus
° Rubella
° Salmonellosis
° Septicemia
° Shigellosis
° Staphylococcus Aureus
° Streptococci
° Syphilis
° Toxoplasmosis
° Trichomonas Vaginalis
° Tuberculosis
° Vibrio
° West Nile Virus
° Yersina
2. Cancer Testing
a. Overview
b. Major Cancer Types
* Prostate
* Lung
* Colon and Rectum
* Breast
* Skin
* Uterine
* Leukemia
* Oral
c. Oncogenes
O Abl/abl-bcr
O AIB1
O BCL-2
O BRCA1
O CD44
O C-fos
O C-myb
O C-myc
O CYP17
O Erb-B
O HPC1
O N-myc
O P40
O P51
O P53
O PIK3CA
O PTI-1
O Ras
O Reg
O Sis
O Src
3. Genetic Diseases
a. Overview
b. Nucleic Acid Amplification
c. Chromosome Imaging
d. Genomics Technologies
e. Proteomics Technologies
f. Current Pharmacogenomic Tests
g. Future Pharmacogenomic Testing
h. Major Diseases
* Achondroplasia
* Autosomal Dominant Polycystic Kidney
Disease
* Cancer
* Cosmetogenomics
* Cystic Fibrosis
* Down's Syndrome
* Duchenne and Becker Muscular Dystrophy
* Factor V (Leiden)
* Factor IX Deficiency
* Fragile X Syndrome
* Heart Disease
* Hemochomatosis
* Hemophilia
* Huntington's Disease
* Maternal-Fetal Incompatibility
* Multiple Endocrine Neoplasia
* Phenylketonuria (PKU)
* Polycystic Kidney Disease (PKD)
* Prenatal Screening
* Retinitis Pigmentosa
* Retinoblastoma
* Sickle Cell Anemia
* Spinal Muscular Atrophy
* Vitamin B12 Metabolism
i. Social Issues and Concerns
4. Forensic Testing
a. Overview
b. Multilocus and Single Locus Probes
* Multilocus Probes
* Single Locus Probes
* PCR and RFLP
c. The FBI
d. DNA Profile Data Banks
* U.S.A.
* U.K.
e. Judicial Implementation
f. Major Crime Categories
g. Factors Contributing to the DNA Probe
Market Expansion
* Technology Availability
* Use of Hair as Evidence
h. Wildlife Forensics
5. Paternity Testing/HLA Typing
6. Other Applications
a. Disease Susceptibility Testing
b. Cardiovascular Diseases
c. Diabetes
d. Alzheimer's Disease
e. Periodontal Disease
f. Plasma Purification
g. Organ Transplantation
h. Water Contamination
i. Other
H. Competing/complementing
1. Monoclonal Antibodies/Immunoassays
2. RNA Probes
3. Two-Dimensional Electrophoresis
4. Flow Cytometry
VII. France Molecular Diagnostics Market
A. Executive Summary
B. Business Environment
C. Market Structure
D. Market Size, Test Volume and Sales Forecasts,
Major Supplier Sales and Market Shares
VIII. Germany Molecular Diagnostics Market
A. Executive Summary
B. Business Environment
C. Market Structure
D. Market Size, Test Volume and Sales Forecasts,
Major Supplier Sales and Market Shares
IX. Italy Molecular Diagnostics Market
A. Executive Summary
B. Business Environment
C. Market Structure
D. Market Size, Test Volume and Sales Forecasts,
Major Supplier Sales and Market Shares
X. Spain Molecular Diagnostics Market
A. Executive Summary
B. Business Environment
C. Market Structure
D. Market Size, Test Volume and Sales Forecasts,
Major Supplier Sales and Market Shares
XI. U.K. Molecular Diagnostics Market
A. Executive Summary
B. Business Environment
C. Market Structure
D. Market Size, Test Volume and Sales Forecasts,
Major Supplier Sales and Market Shares
XII. Competitive Assessments
- Abbott
- Affymetrix
- Agilent Technologies
- Applied Gene Technologies
- Arca Biopharma
- Beckman Coulter/Danaher
- Becton Dickinson
- Biokit
- bioMerieux
- Bio-Rad
- Biotest
- Cepheid
- CellMark Forenciscs/LabCorp
- Decode Genetics
- Diadexus
- Eiken
- Elitech Group
- Enzo
- Exact Sciences
- Fujirebio
- Grifols
- Hologic/Gen-Probe
- Illumina
- Kreatech
- Li-Cor Biosciences
- Monogram Biosciences/LabCorp
- Myriad Genetics
- Ortho-Clinical Diagnostics
- Perkin Elmer/Caliper
- Proteome Sciences
- Qiagen
- Roche
- Scienion
- Sequenom
- Shimadzu
- Siemens
- Sierra Molecular
- Takara Bio
- Tecan Group
- Thermo Fisher
XIII. Appendix: Major Universities and Research Centers
Developing Molecular Diagnostic Technologies



List of Tables


Major Companies Developing or Marketing AIDS Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Adenovirus Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Bartonella Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Campylobacter Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Candida Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Chlamydia Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Clostridium Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Coronavirus Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Cryptosporidium Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing CMV Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Echovirus Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Enterovirus Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing EBV Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Giardia Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Gonorrhea Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Hantavirus Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Helicobacter Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Hepatitis Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Herpes Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Influenza Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Legionella Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Lyme Disease Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Measles Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Meningitis Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Mononucleosis Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Mumps Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Mycoplasma Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Pneumonia Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing RSV Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Rotavirus Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Rubella Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Salmonella Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Septicemia Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Shigella Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Streptococci Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Syphilis Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Toxoplasmosis Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Trichomonas Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Tuberculosis Molecular Diagnostic and Other Direct Identification Tests
Oncogenes Potential Application in Cancer Diagnosis
Major Companies Developing or Marketing Cancer Molecular Diagnostic Tests
Major Companies Developing or Marketing Molecular Diagnostic Tests For Genetic Diseases
France Molecular Diagnostics Test Volume And Sales By Major Application 2014-2019
France Laboratories Performing DNA Sequencing By Market Segment 2014
France Molecular Diagnostics MarketPotential Laboratory Universe by Market Segment 2014
France Molecular Diagnostics Test Volume By Major Application 2014-2019
France Major Infectious Disease Test Volume by Assay 2014-2019
France Major Infectious Disease Test Volume by Method 2014
France Molecular Diagnostics Market By Major Application 2014-2019
France Molecular Diagnostics MarketEstimated Sales And Market Shares of Major Suppliers 2014
France Major Infectious Disease Diagnostics Market by Assay 2014-2019
France AIDS Testing MarketEstimated Sales by Major Supplier 2014
France Adenovirus Testing MarketEstimated Sales by Major Supplier 2014
France Chlamydia Testing MarketEstimated Sales by Major Supplier 2014
France CMV Testing MarketEstimated Sales by Major Supplier 2014
France Gonorrhea Testing MarketEstimated Sales by Major Supplier 2014
France Hepatitis Testing MarketEstimated Sales by Major Supplier 2014
France Hepatitis C Testing MarketEstimated Sales by Major Supplier 2014
France HIV/Hepatitis Blood Screening NAT MarketReagent Sales by Major Supplier 2014
France Herpes Testing MarketEstimated Sales by Major Supplier 2014
France Influenza Testing MarketEstimated Sales by Major Supplier 2014
France Meningitis Testing MarketEstimated Sales by Major Supplier 2014
France Mycoplasma Testing MarketEstimated Sales by Major Supplier 2014
France RSV Testing MarketEstimated Sales by Major Supplier 2014
France Shigella Testing MarketEstimated Sales by Major Supplier 2014
Germany Molecular Diagnostics Test Volume And Sales By Major Application 2014-2019
Germany Laboratories Performing DNA Sequencing By Market Segment 2014
Germany Molecular Diagnostics MarketPotential Laboratory Universe by Market Segment 2014
Germany Molecular Diagnostics Test Volume By Major Application 2014-2019
Germany Major Infectious Disease Test Volume by Assay 2014-2019
Germany Major Infectious Disease Test Volume by Method 2014
Germany Molecular Diagnostics Market By Major Application 2014-2019
Germany Molecular Diagnostics MarketEstimated Sales And Market Shares of Major Suppliers 2014
Germany Major Infectious Disease Diagnostics Market by Assay 2014-2019
Germany AIDS Testing MarketEstimated Sales by Major Supplier 2014
Germany CMV Testing MarketEstimated Sales by Major Supplier 2014
Germany EBV Testing MarketEstimated Sales by Major Supplier 2014
Germany Gonorrhea Testing MarketEstimated Sales by Major Supplier 2014
Germany Hepatitis Testing MarketEstimated Sales by Major Supplier 2014
Germany Hepatitis C Testing MarketEstimated Sales by Major Supplier 2014
Germany HIV/Hepatitis Blood Screening NAT MarketReagent Sales by Major Supplier 2014
Germany Herpes Testing MarketEstimated Sales by Major Supplier 2014
Germany Influenza Testing MarketEstimated Sales by Major Supplier 2014
Germany Meningitis Testing MarketEstimated Sales by Major Supplier 2014
Germany Mycoplasma Testing MarketEstimated Sales by Major Supplier 2014
Germany Pneumonia Testing MarketEstimated Sales by Major Supplier 2014
Germany RSV Testing MarketEstimated Sales by Major Supplier 2014
Germany Rotavirus Testing MarketEstimated Sales by Major Supplier 2014
Italy Molecular Diagnostics Test Volume And Sales By Major Application 2014-2019
Italy Laboratories Performing DNA Sequencing By Market Segment 2014
Italy Molecular Diagnostics MarketPotential Laboratory Universe by Market Segment 2014
Italy Molecular Diagnostics Test Volume By Major Application 2014-2019
Italy Major Infectious Disease Test Volume by Assay 2014-2019
Italy Major Infectious Disease Test Volume by Method 2014
Italy Molecular Diagnostics Market By Major Application 2014-2019
Italy Molecular Diagnostics MarketEstimated Sales And Market Shares of Major Suppliers 2014
Italy Major Infectious Disease Diagnostics Market by Assay 2014-2019
Italy AIDS Testing MarketEstimated Sales by Major Supplier 2014
Italy CMV Testing MarketEstimated Sales by Major Supplier 2014
Italy Gonorrhea Testing MarketEstimated Sales by Major Supplier 2014
Italy Hepatitis Testing MarketEstimated Sales by Major Supplier 2014
Italy Hepatitis C Testing MarketEstimated Sales by Major Supplier 2014
Italy HIV/Hepatitis Blood Screening NAT MarketReagent Sales by Major Supplier 2014
Italy Herpes Testing MarketEstimated Sales by Major Supplier 2014
Italy Influenza Testing MarketEstimated Sales by Major Supplier 2014
Italy Meningitis Testing MarketEstimated Sales by Major Supplier 2014
Italy Mycoplasma Testing MarketEstimated Sales by Major Supplier 2014
Italy RSV Testing MarketEstimated Sales by Major Supplier 2014
Spain Molecular Diagnostics Test Volume And Sales By Major Application 2014-2019
Spain Laboratories Performing DNA Sequencing By Market Segment 2014
Spain Molecular Diagnostics MarketPotential Laboratory Universe by Market Segment 2014
Spain Molecular Diagnostics Test Volume By Major Application 2014-2019
Spain Major Infectious Disease Test Volume by Assay 2014-2019
Spain Major Infectious Disease Test Volume by Method 2014
Spain Molecular Diagnostics Market By Major Application 2014-2019
Spain Molecular Diagnostics MarketEstimated Sales And Market Shares of Major Suppliers 2014
Spain Major Infectious Disease Diagnostics Market by Assay 2014-2019
Spain AIDS Testing MarketEstimated Sales by Major Supplier 2014
Spain Chlamydia Testing MarketEstimated Sales by Major Supplier 2014
Spain CMV Testing MarketEstimated Sales by Major Supplier 2014
Spain Gonorrhea Testing MarketEstimated Sales by Major Supplier 2014
Spain Hepatitis Testing MarketEstimated Sales by Major Supplier 2014
Spain Hepatitis C Testing MarketEstimated Sales by Major Supplier 2014
Spain HIV/Hepatitis Blood Screening NAT MarketReagent Sales by Major Supplier 2014
Spain Herpes Testing MarketEstimated Sales by Major Supplier 2014
Spain Influenza Testing MarketEstimated Sales by Major Supplier 2014
Spain Meningitis Testing MarketEstimated Sales by Major Supplier 2014
Spain Mycoplasma Testing MarketEstimated Sales by Major Supplier 2014
U.K. Molecular Diagnostics Test Volume And Sales By Major Application 2014-2019
U.K. Laboratories Performing DNA Sequencing By Market Segment 2014
U.K. Molecular Diagnostics MarketPotential Laboratory Universe by Market Segment 2014
U.K. Molecular Diagnostics Test Volume By Major Application 2014-2019
U.K. Major Infectious Disease Test Volume by Assay 2014-2019
U.K. Major Infectious Disease Test Volume by Method 2014
U.K. Molecular Diagnostics Market By Major Application 2014-2019
U.K. Molecular Diagnostics MarketEstimated Sales And Market Shares of Major Suppliers 2014
U.K. Major Infectious Disease Diagnostics Market by Assay 2014-2019
U.K. AIDS Testing MarketEstimated Sales by Major Supplier 2014
U.K. Gonorrhea Testing MarketEstimated Sales by Major Supplier 2014
U.K. Hepatitis Testing MarketEstimated Sales by Major Supplier 2014
U.K. Hepatitis C Testing MarketEstimated Sales by Major Supplier 2014
U.K. HIV/Hepatitis Blood Screening NAT MarketReagent Sales by Major Supplier 2014
U.K. Influenza Testing MarketEstimated Sales by Major Supplier 2014
U.K. Mycoplasma Testing MarketEstimated Sales by Major Supplier 2014
U.K. Pneumonia Testing MarketEstimated Sales by Major Supplier 2014
U.K. Shigella Testing MarketEstimated Sales by Major Supplier 2014

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