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Proteomics Research Markets

  • May 2015
  • -
  • Kalorama Information
  • -
  • 165 pages

Proteomics Research Markets examines proteomics research processes in detail and in terms of their instrument and technological requirements relating to mass spectrometry, liquid chromatography and electrophoresis. The instruments and technologies of this report are profiled in terms of their application in proteomics research workflows; analytical strengths and weaknesses; diverse features; major suppliers and their market shares; and market trends. As part of its coverage, the report includes market size estimates (2014) and market projections (2019) for several instrument groups

Table Of Contents

Proteomics Research Markets
ONE: EXECUTIVE SUMMARY
Background
Proteomics in Translational Research
Proteomics in Biomarker Research
Proteomics in Drug Target Research
Proteomics Research Instruments
Mass Spectrometry
Liquid Chromatography
Electrophoresis
Industry Landscape €“ Major Competitors
AB Sciex
Agilent Technologies
Bruker Corporation
Thermo Fisher Scientific
Waters Corporation
Major Conclusions
TWO: INTRODUCTION TO PROTEOMICS RESEARCH
Background
Translational Research
Proteomics and the €˜Omics Landscape
The Role of Proteins in Biological Functioning and Disease
Proteins as Biomarkers
Proteomics Research Samples
Conclusion
THREE: PROTEOMICS RESEARCH TECHNOLOGIES
Background
Mass Spectrometry
Triple Quadrupole
Time-of-Flight
Ion Trap / Orbitrap
Ion Sources
Ion Activation
Reagents
Electrophoresis
Gel Electrophoresis
Off-Gel Electrophoresis
GelFree / Continuous Flow Electrophoresis / Free Flow Electrophoresis
Capillary Electrophoresis
Liquid Chromatography
Conclusion
FOUR: PROTEOMICS RESEARCH PROCESSES €“ BIOMARKER AND DRUG TARGET DEVELOPMENT
Background
Proteomics in Biomarker Research
Biomarker Discovery
Biomarker Verification
Biomarker Validation
Proteomics in Drug Target Research (Chemical Proteomics)
Target Deconvolution
Conclusion
FIVE: PROTEOMICS RESEARCH INSTRUMENT MARKETS
Background
Mass Spectrometry Market in Proteomics Research
Liquid Chromatography Market in Proteomics Research
Electrophoresis Market in Proteomics Research
Proteomics Research Market Overview €“ Technologies, Geographies and Disease
Conclusion
SIX: COMPANY PROFILES
AB Sciex (Danaher)
Background
Products
Revenues
Agilent Technologies
Background
Products
Revenues
Bruker Corporation
Background
Products
Revenues
Thermo Fisher Scientific
Background
Products
Revenues
Waters Corporation
Background
Products
Revenue
Second-Tier Market Players
Bio-Rad Laboratories
Background
Products
GE Healthcare Life Sciences
Background
Products
JEOL Ltd.
Background
Products
Shimadzu Corporation
Background
Products


LIST OF EXHIBITS
ONE: EXECUTIVE SUMMARY
Figure 1-1: Translational Research Workflow Schematic
Table 1-1: Mass Spectrometer Instrument Type Comparison (QqQ, TOF, QIT/LIT,
Orbitrap, FT-ICR) €“ Resolution, Mass Accuracy, Sensitivity, Dynamic Range,Cost
Table 1-2: Proteomics Research Mass Spectrometry Market (Orbitraps, Ion Traps,TOF, Q-TOF, Triple Quadrupole, FT-MS) (2015/2020)
Table 1-3: Proteomics Research Market (Mass Spectrometry, Liquid Chromatography, Electrophoresis) (2015/2020)
Figure 1-2: Proteomics Research Market by Company Share (AB Sciex, Agilent, Bio-Rad Laboratories, Bruker, GE Healthcare Life Sciences, Thermo Fisher Scientific, Waters, Other) (2015)
TWO: INTRODUCTION TO PROTEOMICS RESEARCH
Figure 2-1: Translational Research Workflow Schematic
Figure 2-2: Systems Biology Schematic (Genome, Transcriptome, Proteome,Metabolome)
Table 2-1: Proteomics Research Sample Comparison by Advantages/Disadvantages €“Cell Culture, Dried Blood Spot, Plasma, Serum, Tissue, Whole Blood
THREE: PROTEOMICS RESEARCH TECHNOLOGIES
Table 3-1: Mass Spectrometer Instrument Type Comparison (QqQ, TOF, QIT/LIT,Orbitrap, FT-ICR) €“ Resolution, Mass Accuracy, Sensitivity, Dynamic Range,Cost
Table 3-2: Triple Quadrupole Parameters and Summary (Resolution, Mass Accuracy, Sensitivity, Mass Range, Dynamic Range, Cost, Speed, Advantages/Disadvantages)
Table 3-3: Time-of-Flight / TOF Hybrid Parameters and Summary (Resolution,Mass Accuracy, Sensitivity, Mass Range, Dynamic Range, Cost, Speed,
Advantages/Disadvantages)
Table 3-4: Fourier Transform Ion Cyclotron Resonance Parameters and Summary(Resolution, Mass Accuracy, Sensitivity, Mass Range, Dynamic Range, Cost,Speed, Advantages/Disadvantages)
Table 3-5: Quadrupolar, Linear and Hybrid Ion Trap Parameters and Summary(Resolution, Mass Accuracy, Sensitivity, Mass Range, Dynamic Range, Cost,Speed, Advantages/Disadvantages)
Table 3-6: Orbitrap Parameters and Summary (Resolution, Mass Accuracy,Sensitivity, Mass Range, Dynamic Range, Cost, Speed,Advantages/Disadvantages)
Table 3-7: Major Vendor Electrospray Ionization Innovations Summary
Table 3-8: Surface Analysis Ionization Technique Advantages/Disadvantages(MALDI, SELDI, DESI, LAESI)
Table 3-9: Ion Activation Method Advantages/Disadvantages (Low-Energy CID,High-Energy CID, SID, PSD, ISD, UVPD, IRMPD, ECD, ETD)
Table 3-10: Electrophoresis Method Advantages/Disadvantages (SDS-PAGE, 2DGE,DIGE, OFFGEL, GELFREE, Continuous and Free Flow, Capillary)
FOUR: PROTEOMICS RESEARCH PROCESSES €“ BIOMARKER AND DRUG TARGET DEVELOPMENT
Table 4-1: Shotgun Proteomics Summary (MS Types, Separation/Fractionation Methods, Advantages, Disadvantages)
Table 4-2: Gel-Based Discovery Proteomics Summary (MS Types,Separation/Fractionation Methods, Advantages, Disadvantages)
Table 4-3: Capillary Electrophoresis-Based Discovery Proteomics Summary(MS Types, Separation/Fractionation Methods, Advantages, Disadvantages)
Table 4-4: Data-Independent Acquisition Discovery Proteomics Summary(MS Types, Separation/Fractionation Methods, Advantages, Disadvantages)
Table 4-5: Major Vendor DIA Product Comparison (Waters MSE, Thermo Fisher AIF,AB Sciex SWATH, Thermo Fisher MSX, Thermo Fisher PRM)
Table 4-6: Selected and Multiple Reaction Monitoring (SRM/MRM) Summary(MS Types, Separation/Fractionation Methods, Advantages, Disadvantages)
Table 4-7: Chemical Proteomics/Drug Target Proteomics Summary (MS Types,Separation/Fractionation Methods, Advantages, Disadvantages)
FIVE: ROTEOMICS RESEARCH INSTRUMENT MARKETS
Table 5-1: Proteomics Research Mass Spectrometry Market (Orbitraps, Ion Traps,TOF, Q-TOF, Triple Quadrupole, FT-MS) (2015/2020)
Table 5-2: Proteomics Research Mass Spectrometry Market by Company Share(2015)
Table 5-3: Proteomics Research Liquid Chromatography Market (2015/2020)
Table 5-4: Proteomics Research Liquid Chromatography Market by Company Share(2015)
Table 5-5: Proteomics Research Electrophoresis Market (2015/2020)
Table 5-6: Proteomics Research Market (Mass Spectrometry, Liquid Chromatography, Electrophoresis) (2015/2020)
Table 5-7: Proteomics Research Market by Geography (North America, Europe, Asia-Pacific, ROW) (2015/2020)
Table 5-8: Proteomics Research Market by Disease Area (Cardiovascular, Neurology, Oncology, Other) (2015)
SIX: COMPANY PROFILES
Table 6-1: AB Sciex Proteomics Products
Table 6-2: AB Sciex Revenue (2009-2014)
Table 6-3: Agilent Technologies Proteomics Products
Table 6-4: Agilent Technologies Revenue (FY 2009-2014)
Table 6-5: Bruker Corporation Proteomics Products
Table 6-6: Bruker Corporation Revenue (2009-2014)
Table 6-7: Thermo Fisher Scientific Proteomics Products
Table 6-8: Thermo Fisher Scientific Revenue (2009-2014)
Table 6-9: Waters Corporation Proteomics Products
Table 6-10: Waters Corporation Revenue (2009-2014)
Table 6-11: Bio-Rad Laboratories Proteomics Products
Table 6-12: GE Healthcare Life Sciences Proteomics Products
Table 6-13: JEOL Ltd. Proteomics Products
Table 6-14: Shimadzu Corporation Proteomics Products

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