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  5. > Surgical Sealants and Adhesives Market by Product & Application - Global Forecast to 2020

Surgical sealants and adhesives are a promising alternative to traditional closure techniques—such as sutures, wires, and staples—which have several limitations. For example, they are time-consuming, may cause further tissue trauma, increase the risk of infection, and are difficult to use in some surgical locations. Moreover, none of these techniques create immediate and proper sealing. Surgical sealants and adhesives will potentially replace sutures and staples because of their better closure capabilities, minimized blood loss, faster implementation, and as they facilitate an easy and less painful operation, without the need for removal. They are also used as adjuncts to sutures to prevent air and liquid leakages. The major application areas of surgical sealants and adhesives include the central nervous system, cardiovascular, general surgery, orthopedic, pulmonary, urology ophthalmology, and others (ENT, dental, and trauma).

The global surgical sealants and adhesives market is expected to grow at a steady CAGR of 9.2% during the forecast period (2015 to 2020). The market is mainly driven by the increasing applications of surgical sealants and adhesives, growing need to manage blood loss, greater uptake of technologically advanced products, and increasing regulatory approvals.

In this report, the market is segmented by product, application, and region. The surgical sealants and adhesives market is broadly split into two product segments—natural or biological and synthetic & semisynthetic sealants and adhesives. The natural or biological sealants and adhesives market accounted for the largest share of approximately 60% of the surgical sealants and adhesives product market in 2014, and is expected to grow at a CAGR of 8.1% during the forecast period of 2015 to 2020. The large share of this segment is mainly due to the wide use and application of fibrin sealants owing to their better biocompatibility, natural clotting mechanism, and wide application range. The natural or biological sealants and adhesives segment is further segmented on the basis of type and origin. On the basis of type, natural or biological sealants and adhesives are categorized into fibrin sealants, collagen-based, and gelatin-based adhesives. Based on origin, they are categorized into human blood and animal-based sealants and adhesives.

The synthetic and semisynthetic surgical sealants and adhesives is segmented into cyanoacrylates, polymeric hydrogels, urethane-based adhesives. Polymeric hydrogel-based sealants and adhesives accounted for the largest share of the global synthetic and semisynthetic sealants/adhesives owing to their improved mechanical properties, such as high elasticity.

Based on application, the surgical sealants and adhesives market is segmented into the central nervous system, cardiovascular, general surgery, orthopedic, pulmonary, urology, cosmetic, ophthalmology, and others. The central nervous system segment accounted for ~20% of the surgical sealants and adhesives market in 2014. This is mainly due to the extensive use of surgical sealants and adhesives in nerve and spine surgeries.

In 2014, North America commanded the largest share of the global surgical sealants and adhesives market, followed by Europe, Asia-Pacific, and the RoW. During the forecast period, developed geographic markets such as North America and Europe are likely to grow at a lower CAGR than the Asia-Pacific market. Growth in the Asia-Pacific market is largely driven by the rise in health awareness, growth of aging population, increase in number of surgical procedures, and growth in per capita income.

The major players in the surgical sealants and adhesives market are Baxter International, Inc. (U.S.), CryoLife, Inc. (U.S.), C.R. Bard, Inc. (U.S.), Johnson and Johnson (Ethicon, Inc.) (U.S.), Medtronic plc (U.S.), Sanofi Group (France), B. Braun Melsungen AG (Germany), Cohera Medical, Inc. (U.S.), Sealantis (Israel), and Vivostat A/S (Denmark).

Reasons to Buy the Report
The report will enrich established firms as well as new entrants/smaller firms to gauge the pulse of the market, which in turn would help them garner a greater market share. Firms purchasing the report could use one or any combination of the below-mentioned five strategies (market penetration, product development/innovation, market development, market diversification, and competitive assessment) for reaping greater market shares.

This report provides insights on the following pointers:
- Market Penetration: Comprehensive information on product portfolios offered by top players in the surgical sealants and adhesives market. The report analyzes the surgical sealants and adhesives market by product and by application across all regions
- Product Development/Innovation: Detailed insights on upcoming trends, R&D activities, and new product launches in the surgical sealants and adhesives market
- Market Development: Comprehensive information on the lucrative emerging markets by product, application, and region
- Market Diversification: Exhaustive information about new products, growing regions, recent developments, and investments in the surgical sealants and adhesives market
- Competitive Assessment: In-depth assessment of market shares, growth strategies, products, distribution networks, manufacturing capabilities, and SWOT analyses of leading players in the surgical sealants and adhesives market

Table Of Contents

Surgical Sealants and Adhesives Market by Product and Application - Global Forecast to 2020
TABLE OF CONTENTS

1 INTRODUCTION 18
1.1 OBJECTIVES OF THE STUDY 18
1.2 MARKET DEFINITION 18
1.3 MARKET SCOPE 19
1.3.1 MARKETS COVERED 20
1.3.2 YEARS CONSIDERED FOR THE STUDY 21
1.4 CURRENCY 22
1.5 STAKEHOLDERS 22
2 RESEARCH METHODOLOGY 23
2.1 RESEARCH APPROACH 23
2.1.1 SECONDARY DATA 24
2.1.1.1 Key data from secondary sources 24
2.1.2 PRIMARY DATA 25
2.1.2.1 Key data from primary sources 25
2.1.2.2 Key industry insights 26
2.2 MARKET SIZE ESTIMATION 27
2.3 MARKET BREAKDOWN AND DATA TRIANGULATION 29
2.4 MARKET SHARE ESTIMATION 30
2.5 RESEARCH ASSUMPTIONS 30
2.5.1 ASSUMPTIONS FOR THE STUDY 30
3 EXECUTIVE SUMMARY 31
4 PREMIUM INSIGHTS 36
4.1 SURGICAL SEALANTS AND ADHESIVES MARKET OVERVIEW 36
4.2 ASIA-PACIFIC SURGICAL SEALANTS AND ADHESIVES MARKET: BY PRODUCT 36
4.3 SURGICAL SEALANTS AND ADHESIVES MARKET: GEOGRAPHIC SNAPSHOT 37
4.4 SURGICAL SEALANTS AND ADHESIVES MARKET: BY REGION 38
4.5 SURGICAL SEALANTS AND ADHESIVES MARKET SHARE: BY PRODUCT 38
5 MARKET OVERVIEW 39
5.1 INTRODUCTION 40
5.2 MARKET DYNAMICS 41
5.3 KEY MARKET DRIVERS 42
5.3.1 GROWING NEED TO MANAGE BLOOD LOSS IN PATIENTS 42
5.3.2 RISING NUMBER OF SURGICAL PROCEDURES ACROSS THE GLOBE 42
5.3.3 GREATER UPTAKE OF TECHNOLOGICALLY ADVANCED PRODUCTS 43
5.3.4 FDA AND CE MARK APPROVALS DRIVING ADOPTION OF SURGICAL SEALANTS AND ADHESIVES 43
5.4 KEY MARKET RESTRAINTS 45
5.4.1 LACK OF REIMBURSEMENTS FOR SURGICAL SEALANTS AND ADHESIVES 45
5.4.2 HIGH COSTS AND CLINICAL DATA REQUIREMENTS FOR LAUNCHING NEW PRODUCTS 45
5.5 KEY MARKET OPPORTUNITIES 46
5.5.1 EMERGING MARKETS 46
5.6 KEY CHALLENGES 47
5.6.1 DEVELOPMENT OF NOVEL BIOMATERIALS WITH HIGH MECHANICAL PROPERTIES AND HIGH ADHESION STRENGTH 47
5.6.2 NEED OF SKILLED PERSONNEL FOR THE EFFECTIVE USE OF SURGICAL SEALANTS AND ADHESIVES 47
6 INDUSTRY INSIGHTS 49
6.1 INTRODUCTION 49
6.2 INDUSTRY TRENDS 49
6.2.1 GROWING PREFERENCE FOR GELATIN-BASED ADHESIVES AND POLYMERIC HYDROGELS IN SURGICAL PROCEDURES 49
6.2.2 INCREASING NUMBER OF ACQUISITIONS DRIVING CONSOLIDATION IN THE MARKET 50
6.3 PORTER'S FIVE FORCES ANALYSIS 50
6.3.1 THREAT OF NEW ENTRANTS 51
6.3.2 THREAT OF SUBSTITUTES 51
6.3.3 BARGAINING POWER OF SUPPLIERS 52
6.3.4 BARGAINING POWER OF BUYERS 52
6.3.5 INTENSITY OF COMPETITIVE RIVALRY 53
6.4 STRATEGIC BENCHMARKING 53
6.4.1 PRODUCT PORTFOLIO ANALYSIS: SURGICAL SEALANTS AND ADHESIVES MARKET 54
7 SURGICAL SEALANTS AND ADHESIVES MARKET, BY PRODUCT 56
7.1 INTRODUCTION 57
7.2 NATURAL/BIOLOGICAL SEALANTS AND ADHESIVES 58
7.2.1 NATURAL/BIOLOGICAL SEALANTS AND ADHESIVES, BY TYPE 59
7.2.1.1 Fibrin sealants 60
7.2.1.2 Collagen-based Adhesives 61
7.2.1.3 Gelatin-based Adhesives 62
7.2.2 NATURAL/BIOLOGICAL SEALANTS AND ADHESIVES, BY ORIGIN 64
7.2.2.1 Human Blood-based 65
7.2.2.2 Animal-based adhesives and sealants 66

7.3 SYNTHETIC AND SEMISYNTHETIC ADHESIVES AND SEALANTS 67
7.3.1 CYANOACRYLATES 69
7.3.2 POLYMERIC HYDROGELS 70
7.3.3 URETHANE-BASED ADHESIVES 72
8 SURGICAL SEALANTS AND ADHESIVES MARKET, BY APPLICATION 73
8.1 INTRODUCTION 74
8.2 CENTRAL NERVOUS SYSTEM (CNS) SURGERIES 75
8.3 GENERAL SURGERIES (LIVER, GASTROINTESTINAL, PANCREATIC, SPLEEN SURGERIES, HERNIA REPAIR) 77
8.4 CARDIOVASCULAR SURGERIES 78
8.5 ORTHOPEDIC SURGERIES 80
8.6 COSMETIC SURGERIES 82
8.7 UROLOGICAL SURGERIES 83
8.8 OPHTHALMIC SURGERIES 84
8.9 PULMONARY SURGERIES 86
8.10 OTHER APPLICATIONS 87
9 GEOGRAPHIC ANALYSIS 89
9.1 INTRODUCTION 90
9.2 NORTH AMERICA 91
9.2.1 U.S. 95
9.2.2 CANADA 98
9.3 EUROPE 101
9.3.1 GERMANY 105
9.3.2 FRANCE 108
9.3.3 U.K. 111
9.3.4 ITALY 113
9.3.5 SPAIN 116
9.3.6 REST OF EUROPE 118
9.4 ASIA-PACIFIC 121
9.4.1 JAPAN 125
9.4.2 CHINA 128
9.4.3 INDIA 131
9.4.4 REST OF ASIA-PACIFIC 133
9.5 REST OF THE WORLD (ROW) 136
9.5.1 LATIN AMERICA 138
9.5.2 MIDDLE EAST AND AFRICA 141

10 COMPETITIVE LANDSCAPE 144
10.1 OVERVIEW 144
10.2 MARKET SHARE ANALYSIS 145
10.3 COMPETITIVE SITUATION AND TRENDS 147
10.3.1 REGULATORY APPROVALS 148
10.3.2 MERGERS AND ACQUISITIONS 149
10.3.3 AGREEMENTS AND COLLABORATIONS 150
10.3.4 EXPANSIONS 151
10.3.5 NEW PRODUCT LAUNCHES 152
10.3.6 OTHERS 152
11 COMPANY PROFILES 153
11.1 INTRODUCTION 153
11.2 BAXTER INTERNATIONAL, INC. 154
11.2.1 BUSINESS OVERVIEW 154
11.2.2 PRODUCT OFFERINGS 155
11.2.3 RECENT DEVELOPMENTS 155
11.2.4 MNM VIEW 155
11.3 JOHNSON and JOHNSON (ETHICON, INC.) 156
11.3.1 BUSINESS OVERVIEW 156
11.3.2 PRODUCT OFFERINGS 157
11.3.3 RECENT DEVELOPMENTS 157
11.3.4 MNM VIEW 157
11.4 MEDTRONIC PLC 158
11.4.1 BUSINESS OVERVIEW 158
11.4.2 PRODUCT OFFERINGS 159
11.4.3 RECENT DEVELOPMENTS 159
11.4.4 MNM VIEW 160
11.5 CRYOLIFE, INC. 161
11.5.1 BUSINESS OVERVIEW 161
11.5.2 PRODUCT OFFERINGS 162
11.5.3 RECENT DEVELOPMENTS 162
11.5.4 MNM VIEW 162
11.6 C.R. BARD, INC. 163
11.6.1 BUSINESS OVERVIEW 163
11.6.2 PRODUCT OFFERINGS 164
11.6.3 RECENT DEVELOPMENTS 164
11.6.4 MNM VIEW 164
11.7 SANOFI GROUP 165
11.7.1 BUSINESS OVERVIEW 165
11.7.2 PRODUCT OFFERINGS 166
11.7.3 RECENT DEVELOPMENTS 166
11.8 B. BRAUN MELSUNGEN AG 167
11.8.1 BUSINESS OVERVIEW 167
11.8.2 PRODUCT OFFERINGS 168
11.8.3 RECENT DEVELOPMENTS 168
11.9 COHERA MEDICAL INC. 169
11.9.1 BUSINESS OVERVIEW 169
11.9.2 FINANCIALS 169
11.9.3 PRODUCT OFFERINGS 169
11.9.4 RECENT DEVELOPMENTS 169
11.10 OCULAR THERAPEUTIX, INC. 170
11.10.1 BUSINESS OVERVIEW 170
11.10.2 FINANCIALS 170
11.10.3 PRODUCT OFFERINGS 170
11.10.4 RECENT DEVELOPMENTS 170
11.11 VIVOSTAT A/S 171
11.11.1 BUSINESS OVERVIEW 171
11.11.2 FINANCIALS 171
11.11.3 PRODUCT OFFERINGS 171
11.11.4 RECENT DEVELOPMENTS 171
12 APPENDIX 172
12.1 INSIGHTS OF INDUSTRY EXPERTS 172
12.2 DISCUSSION GUIDE 173
12.3 OTHER DEVELOPMENTS 177
12.4 AVAILABLE CUSTOMIZATIONS 177
12.5 INTRODUCING RT: REAL-TIME MARKET INTELLIGENCE 178
12.6 RELATED REPORTS 180


LIST OF TABLES

TABLE 1 GROWING NEED TO MANAGE BLOOD LOSS IN PATIENTS WITH EFFECTIVE SEALANTS AND ADHESIVES TO DRIVE MARKET GROWTH 44
TABLE 2 HIGH COSTS ASSOCIATED WITH SURGICAL SEALANTS AND ADHESIVES RESTRAINING MARKET GROWTH 46
TABLE 3 EMERGING MARKETS TO PROVIDE SIGNIFICANT GROWTH OPPORTUNITIES FOR PLAYERS 47
TABLE 4 DEVELOPMENT OF ADVANCED ADHESIVES AND SURGICAL SEALANTS WITH A HIGH ADHESION STRENGTH IS A MAJOR CHALLENGE 48
TABLE 5 GLOBAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY TYPE,
2013-2020 ($MILLION) 57
TABLE 6 GLOBAL NATURAL/BIOLOGICAL SEALANTS AND ADHESIVES MARKET SIZE,
BY COUNTRY/REGION, 2013-2020 ($MILLION) 59
TABLE 7 GLOBAL NATURAL/BIOLOGICAL SEALANTS AND ADHESIVES MARKET SIZE,
BY TYPE, 2013-2020 ($MILLION) 59
TABLE 8 GLOBAL FIBRIN SEALANTS MARKET SIZE, BY COUNTRY/REGION,
2013-2020 ($MILLION) 61
TABLE 9 GLOBAL COLLAGEN-BASED ADHESIVES MARKET SIZE, BY COUNTRY/REGION, 2013-2020 ($MILLION) 62
TABLE 10 GLOBAL GELATIN-BASED ADHESIVES MARKET SIZE, BY COUNTRY/REGION,
2013-2020 ($MILLION) 63
TABLE 11 GLOBAL NATURAL/BIOLOGICAL SEALANTS MARKET SIZE, BY ORIGIN,
2013-2020 ($MILLION) 64
TABLE 12 GLOBAL HUMAN BLOOD-BASED SEALANTS/ADHESIVES MARKET SIZE,
BY COUNTRY/REGION, 2013-2020 ($MILLION) 65
TABLE 13 GLOBAL ANIMAL-BASED SEALANTS AND ADHESIVES MARKET SIZE,
BY COUNTRY/REGION, 2013-2020 ($MILLION) 66
TABLE 14 GLOBAL SYNTHETIC AND SEMISYNTHETIC SEALANTS AND ADHESIVES MARKET SIZE, BY TYPE, 2013-2020 ($MILLION) 68
TABLE 15 GLOBAL SYNTHETIC AND SEMISYNTHETIC SEALANTS AND ADHESIVES MARKET SIZE, BY COUNTRY/REGION, 2013-2020 ($MILLION) 68
TABLE 16 GLOBAL CYANOACRYLATES MARKET SIZE, BY COUNTRY/REGION,
2013-2020 ($MILLION) 70
TABLE 17 GLOBAL POLYMERIC HYDROGELS MARKET SIZE, BY COUNTRY/REGION,
2013-2020 ($MILLION) 71
TABLE 18 GLOBAL URETHANE-BASED ADHESIVES MARKET SIZE, BY COUNTRY/REGION, 2013-2020 ($MILLION) 72
TABLE 19 GLOBAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY APPLICATION, 2013-2020 ($MILLION) 74
TABLE 20 GLOBAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE FOR CNS SURGERIES, BY COUNTRY/REGION, 2013-2020 ($MILLION) 76
TABLE 21 GLOBAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE FOR GENERAL SURGERIES, BY COUNTRY/REGION, 2013-2020 ($MILLION) 78

TABLE 22 GLOBAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE FOR CARDIOVASCULAR SURGERIES, BY COUNTRY/REGION, 2013-2020 ($MILLION) 80
TABLE 23 GLOBAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE FOR ORTHOPEDIC SURGERIES, BY COUNTRY/REGION, 2013-2020 ($MILLION) 81
TABLE 24 GLOBAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE FOR COSMETIC SURGERIES, BY COUNTRY/REGION, 2013-2020 ($MILLION) 82
TABLE 25 GLOBAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE FOR UROLOGICAL SURGERIES, BY COUNTRY/REGION, 2013-2020 ($MILLION) 84
TABLE 26 GLOBAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE FOR OPHTHALMIC SURGERIES, BY COUNTRY/REGION, 2013-2020 ($MILLION) 85
TABLE 27 GLOBAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE FOR PULMONARY SURGERIES, BY COUNTRY/REGION, 2013-2020 ($MILLION) 87
TABLE 28 GLOBAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE FOR OTHER APPLICATIONS, BY COUNTRY/REGION, 2013-2020 ($MILLION) 88
TABLE 29 GLOBAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY REGION,
2013-2020 ($MILLION) 91
TABLE 30 NORTH AMERICA: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE,
BY COUNTRY, 2013-2020 ($MILLION) 93
TABLE 31 NORTH AMERICA: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE,
BY PRODUCT, 2013- 2020 ($MILLION) 93
TABLE 32 NORTH AMERICA: NATURAL/BIOLOGICAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY TYPE, 2013-2020 ($MILLION) 93
TABLE 33 NORTH AMERICA: NATURAL/BIOLOGICAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY ORIGIN, 2013-2020 ($MILLION) 94
TABLE 34 NORTH AMERICA: SYNTHETIC AND SEMISYNTHETIC SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY TYPE, 2013-2020 ($MILLION) 94
TABLE 35 NORTH AMERICA: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY APPLICATION, 2013- 2020 ($MILLION) 95
TABLE 36 U.S.: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY PRODUCT,
2013- 2020 ($MILLION) 96
TABLE 37 U.S.: NATURAL AND BIOLOGICAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY TYPE, 2013-2020 ($MILLION) 96
TABLE 38 U.S.: NATURAL/BIOLOGICAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY ORIGIN, 2013-2020 ($MILLION) 97
TABLE 39 U.S.: SYNTHETIC AND SEMISYNTHETIC SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY TYPE, 2013-2020 ($MILLION) 97
TABLE 40 U.S.: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY APPLICATION, 2013-2020 ($MILLION) 98
TABLE 41 CANADA: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY PRODUCT, 2013- 2020 ($MILLION) 99
TABLE 42 CANADA: NATURAL/BIOLOGICAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY TYPE, 2013-2020 ($MILLION) 99
TABLE 43 CANADA: NATURAL/BIOLOGICAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY ORIGIN, 2013-2020 ($MILLION) 100
TABLE 44 CANADA: SYNTHETIC AND SEMISYNTHETIC SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY TYPE, 2013-2020 ($MILLION) 100
TABLE 45 CANADA: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY APPLICATION, 2013- 2020 ($MILLION) 101

TABLE 46 EUROPE: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY COUNTRY, 2013-2020 ($MILLION) 103
TABLE 47 EUROPE: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY PRODUCT, 2013-2020 ($MILLION) 103
TABLE 48 EUROPE: NATURAL/BIOLOGICAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY TYPE, 2013-2020 ($MILLION) 104
TABLE 49 EUROPE: NATURAL/BIOLOGICAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY ORIGIN, 2013-2020 ($MILLION) 104
TABLE 50 EUROPE: SYNTHETIC AND SEMISYNTHETIC SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY TYPE, 2013-2020 ($MILLION) 104
TABLE 51 EUROPE: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY APPLICATION, 2013-2020 ($MILLION) 105
TABLE 52 GERMANY: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY PRODUCT, 2013-2020 ($MILLION) 106
TABLE 53 GERMANY: NATURAL/BIOLOGICAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY TYPE, 2013-2020 ($MILLION) 106
TABLE 54 GERMANY: NATURAL/BIOLOGICAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY ORIGIN, 2013-2020 ($MILLION) 107
TABLE 55 GERMANY: SYNTHETIC AND SEMISYNTHETIC SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY TYPE, 2013-2020 ($MILLION) 107
TABLE 56 GERMANY: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY APPLICATION, 2013- 2020 ($MILLION) 108
TABLE 57 FRANCE: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY PRODUCT, 2013-2020 ($MILLION) 109
TABLE 58 FRANCE: NATURAL/BIOLOGICAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY TYPE, 2013-2020 ($MILLION) 109
TABLE 59 FRANCE: NATURAL/BIOLOGICAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY ORIGIN, 2013-2020 ($MILLION) 109
TABLE 60 FRANCE: SYNTHETIC AND SEMISYNTHETIC SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY TYPE, 2013-2020 ($MILLION) 110
TABLE 61 FRANCE: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY APPLICATION, 2013-2020 ($MILLION) 110
TABLE 62 U.K.: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY PRODUCT, 2013- 2020 ($MILLION) 111
TABLE 63 U.K.: NATURAL/BIOLOGICAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY TYPE, 2013-2020 ($MILLION) 112
TABLE 64 U.K.: NATURAL/BIOLOGICAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY ORIGIN, 2013-2020 ($MILLION) 112
TABLE 65 U.K.: SYNTHETIC AND SEMISYNTHETIC SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY TYPE, 2013-2020 ($MILLION) 112
TABLE 66 U.K.: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY APPLICATION, 2013-2020 ($MILLION) 113
TABLE 67 ITALY: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY PRODUCT, 2013-2020 ($MILLION) 114
TABLE 68 ITALY: NATURAL/BIOLOGICAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY TYPE, 2013-2020 ($MILLION) 114
TABLE 69 ITALY: NATURAL/BIOLOGICAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY ORIGIN, 2013-2020 ($MILLION) 114

TABLE 70 ITALY: SYNTHETIC AND SEMISYNTHETIC SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY TYPE, 2013-2020 ($MILLION) 115
TABLE 71 ITALY: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY APPLICATION, 2013-2020 ($MILLION) 115
TABLE 72 SPAIN: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY PRODUCT,
2013-2020 ($MILLION) 116
TABLE 73 SPAIN: NATURAL/BIOLOGICAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY TYPE, 2013-2020 ($MILLION) 117
TABLE 74 SPAIN: NATURAL/BIOLOGICAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY ORIGIN, 2013-2020 ($MILLION) 117
TABLE 75 SPAIN: SYNTHETIC AND SEMISYNTHETIC SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY TYPE, 2013-2020 ($MILLION) 117
TABLE 76 SPAIN: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY APPLICATION, 2013- 2020 ($MILLION) 118
TABLE 77 ROE: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY PRODUCT,
2013-2020 ($MILLION) 119
TABLE 78 ROE: NATURAL/BIOLOGICAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY TYPE, 2013-2020 ($MILLION) 119
TABLE 79 ROE: NATURAL/BIOLOGICAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY ORIGIN, 2013-2020 ($MILLION) 120
TABLE 80 ROE: SYNTHETIC AND SEMISYNTHETIC SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY TYPE, 2013-2020 ($MILLION) 120
TABLE 81 ROE: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY APPLICATION, 2013- 2020 ($MILLION) 121
TABLE 82 ASIA-PACIFIC: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY COUNTRY/REGION, 2013-2020 ($MILLION) 123
TABLE 83 ASIA-PACIFIC: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY PRODUCT, 2013- 2020 ($MILLION) 123
TABLE 84 ASIA-PACIFIC: NATURAL/BIOLOGICAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY TYPE, 2013-2020 ($MILLION) 123
TABLE 85 ASIA-PACIFIC: NATURAL/BIOLOGICAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY ORIGIN, 2013-2020 ($MILLION) 124
TABLE 86 ASIA-PACIFIC: SYNTHETIC AND SEMISYNTHETIC SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY ORIGIN, 2013-2020 ($MILLION) 124
TABLE 87 ASIA-PACIFIC: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY APPLICATION, 2013- 2020 ($MILLION) 125
TABLE 88 JAPAN: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY PRODUCT,
2013-2020 ($MILLION) 126
TABLE 89 JAPAN: NATURAL/BIOLOGICAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY TYPE, 2013-2020 ($MILLION) 126
TABLE 90 JAPAN: NATURAL/BIOLOGICAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY ORIGIN, 2013-2020 ($MILLION) 127
TABLE 91 JAPAN: SYNTHETIC AND SEMISYNTHETIC SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY TYPE, 2013-2020 ($MILLION) 127
TABLE 92 JAPAN: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY APPLICATION, 2013-2020 ($MILLION) 128
TABLE 93 CHINA: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY PRODUCT,
2013-2020 ($MILLION) 129

TABLE 94 CHINA : NATURAL/BIOLOGICAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY TYPE, 2013-2020 ($MILLION) 129
TABLE 95 CHINA: NATURAL/BIOLOGICAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY ORIGIN, 2013-2020 ($MILLION) 129
TABLE 96 CHINA: SYNTHETIC AND SEMISYNTHETIC SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY TYPE, 2013-2020 ($MILLION) 130
TABLE 97 CHINA: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY APPLICATION, 2013-2020 ($MILLION) 130
TABLE 98 INDIA: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY PRODUCT,
2013-2020 ($MILLION) 131
TABLE 99 INDIA: NATURAL/BIOLOGICAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY TYPE, 2013-2020 ($MILLION) 132
TABLE 100 INDIA: NATURAL/BIOLOGICAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY ORIGIN, 2013-2020 ($MILLION) 132
TABLE 101 INDIA: SYNTHETIC AND SEMISYNTHETIC SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY TYPE, 2013-2020 ($MILLION) 132
TABLE 102 INDIA: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY APPLICATION, 2013-2020 ($MILLION) 133
TABLE 103 ROAPAC: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY PRODUCT, 2013-2020 ($MILLION) 134
TABLE 104 ROAPAC: NATURAL/BIOLOGICAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY TYPE, 2013-2020 ($MILLION) 134
TABLE 105 ROAPAC: NATURAL/BIOLOGICAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY ORIGIN, 2013-2020 ($MILLION) 134
TABLE 106 ROAPAC: SYNTHETIC AND SEMISYNTHETIC SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY TYPE, 2013-2020 ($MILLION) 135
TABLE 107 ROAPAC: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY APPLICATION, 2013-2020 ($MILLION) 135
TABLE 108 ROW: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY REGION,
2013-2020 ($MILLION) 136
TABLE 109 ROW: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY PRODUCT,
2013-2020 ($MILLION) 136
TABLE 110 ROW: NATURAL/BIOLOGICAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY TYPE, 2013-2020 ($MILLION) 137
TABLE 111 ROW: NATURAL/BIOLOGICAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY ORIGIN, 2013-2020 ($MILLION) 137
TABLE 112 ROW: SYNTHETIC AND SEMISYNTHETIC SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY TYPE, 2013-2020 ($MILLION) 137
TABLE 113 ROW: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY APPLICATION, 2013-2020 ($MILLION) 138
TABLE 114 LATIN AMERICA: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY PRODUCT, 2013-2020 ($MILLION) 139
TABLE 115 LATIN AMERICA: NATURAL/BIOLOGICAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY TYPE, 2013-2020 ($MILLION) 139
TABLE 116 LATIN AMERICA: NATURAL/BIOLOGICAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY ORIGIN, 2013-2020 ($MILLION) 139
TABLE 117 LATIN AMERICA: SYNTHETIC AND SEMISYNTHETIC SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY TYPE, 2013-2020 ($MILLION) 140

TABLE 118 LATIN AMERICA: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY APPLICATION, 2013-2020 ($MILLION) 140
TABLE 119 MIDDLE EAST AND AFRICA: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY PRODUCT, 2013-2020 ($MILLION) 141
TABLE 120 MIDDLE EAST AND AFRICA: NATURAL/BIOLOGICAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY TYPE, 2013-2020 ($MILLION) 142
TABLE 121 MIDDLE EAST AND AFRICA: NATURAL/BIOLOGICAL SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY ORIGIN, 2013-2020 ($MILLION) 142
TABLE 122 MIDDLE EAST AND AFRICA: SYNTHETIC AND SEMISYNTHETIC SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY TYPE, 2013-2020 ($MILLION) 143
TABLE 123 MIDDLE EAST AND AFRICA: SURGICAL SEALANTS AND ADHESIVES MARKET SIZE, BY APPLICATION, 2013-2020 ($MILLION) 143
TABLE 124 GROWTH STRATEGY MATRIX, 2011-2015 145
TABLE 125 REGULATORY APPROVALS::RECENT DEVELOPMENTS, 2012-2015 148
TABLE 126 MERGERS AND ACQUISITIONS::RECENT DEVELOPMENTS, 2012-2015 149
TABLE 127 AGREEMENTS AND COLLABORATIONS::RECENT DEVELOPMENTS, 2012-2015 150
TABLE 128 EXPANSION::RECENT DEVELOPMENTS, 2012-2015 151
TABLE 129 NEW PRODUCT LAUNCHES::RECENT DEVELOPMENTS, 2012-2015 152
TABLE 130 OTHERS::RECENT DEVELOPMENTS, 2012-2015 152



LIST OF FIGURES

FIGURE 1 SURGICAL SEALANTS AND ADHESIVES MARKET 20
FIGURE 2 RESEARCH DESIGN 23
FIGURE 3 BREAKDOWN OF PRIMARY INTERVIEWS: BY COMPANY TYPE, DESIGNATION, AND REGION 26
FIGURE 4 BOTTOM-UP APPROACH 27
FIGURE 5 TOP-DOWN APPROACH 28
FIGURE 6 DATA TRIANGULATION METHODOLOGY 29
FIGURE 7 SYNTHETIC AND SEMISYNTHETIC SEALANTS AND ADHESIVES TO REGISTER MAXIMUM GROWTH DURING THE FORECAST PERIOD 32
FIGURE 8 GELATIN-BASED ADHESIVES SEGMENT EXPECTED TO GROW AT THE HIGHEST CAGR AMONG NATURAL/BIOLOGICAL SEALANTS AND ADHESIVES 33
FIGURE 9 COSMETIC SURGERY APPLICATION SEGMENT TO REGISTER THE HIGHEST GROWTH DURING THE FORECAST PERIOD 34
FIGURE 10 GEOGRAPHIC ANALYSIS: GLOBAL SURGICAL SEALANTS AND ADHESIVES MARKET (2014) 35
FIGURE 11 RISING NUMBER OF SURGICAL PROCEDURES DRIVING MARKET GROWTH 36
FIGURE 12 FIBRIN SEALANTS ACCOUNTED FOR A MAJOR SHARE IN ASIA-PACIFIC SURGICAL SEALANTS AND ADHESIVES MARKET 36
FIGURE 13 THE U.S. ACCOUNTED FOR THE LARGEST SHARE OF THE GLOBAL SURGICAL SEALANTS AND ADHESIVES MARKET 37
FIGURE 14 NORTH AMERICA TO DOMINATE THE SURGICAL SEALANTS AND ADHESIVES MARKET IN THE FORECAST PERIOD 38
FIGURE 15 GELATIN BASED-ADHESIVES TO COMMAND THE LARGEST MARKET SHARE
BY 2020 38
FIGURE 16 SURGICAL SEALANTS and ADHESIVES MARKET, BY PRODUCT 40
FIGURE 17 SURGICAL SEALANTS and ADHESIVES MARKET, BY APPLICATION 40
FIGURE 18 SURGICAL SEALANTS and ADHESIVES MARKET: DRIVERS, RESTRAINTS, OPPORTUNITIES, AND CHALLENGES 41
FIGURE 19 GELATIN-BASED ADHESIVES TO REGISTER THE HIGHEST GROWTH DURING THE FORECAST PERIOD 58
FIGURE 20 ANIMAL-BASED SURGICAL SEALANTS AND ADHESIVES TO GROW AT A
HIGHER CAGR 64
FIGURE 21 ASIA-PACIFIC MARKET FOR SYNTHETIC and SEMISYNTHETIC SEALANTS AND ADHESIVES TO SHOW HIGHEST GROWTH 67
FIGURE 22 CARDIOVASCULAR SURGERIES SEGMENT HOLDS MAJOR SHARE OF THE SURGICAL SEALANTS AND ADHESIVES MARKET 75
FIGURE 23 GLOBAL SURGICAL SEALANTS AND ADHESIVES MARKET: REGIONAL SNAPSHOT 90
FIGURE 24 NORTH AMERICAN MARKET SNAPSHOT: SURGICAL SEALANTS AND ADHESIVES MARKET 92
FIGURE 25 EUROPEAN SURGICAL SEALANTS AND ADHESIVES MARKET SNAPSHOT 102
FIGURE 26 ASIA-PACIFIC SURGICAL SEALANTS AND ADHESIVES MARKET SNAPSHOT: CHINA AND INDIA ARE THE MOST LUCRATIVE MARKETS 122
FIGURE 27 MARKET PLAYERS MAJORLY ADOPTED REGULATORY APPROVAL AS KEY GROWTH STRATEGY BETWEEN 2012 AND 2015 144
FIGURE 28 SURGICAL SEALANTS AND ADHESIVES MARKET SHARE ANALYSIS, BY KEY
PLAYER, 2014 146
FIGURE 29 BATTLE FOR MARKET SHARE: REGULATORY APPROVALS WAS THE KEY STRATEGY 147
FIGURE 30 GEOGRAPHY REVENUE MIX OF TOP MARKET PLAYERS 153
FIGURE 31 COMPANY SNAPSHOT: BAXTER INTERNATIONAL, INC. 154
FIGURE 32 COMPANY SNAPSHOT: JOHNSON and JOHNSON 156
FIGURE 33 COMPANY SNAPSHOT: MEDTRONIC PLC 158
FIGURE 34 COMPANY SNAPSHOT: CRYOLIFE, INC. 161
FIGURE 35 COMPANY SNAPSHOT: C.R. BARD, INC. 163
FIGURE 36 COMPANY SNAPSHOT: SANOFI GROUP 165
FIGURE 37 COMPANY SNAPSHOT: B. BRAUN MELSUNGEN AG 167

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